Cardiovascular safety of anagrelide in healthy subjects: effects of caffeine and food intake on pharmacokinetics and adverse reactions.
Clinical drug investigation2013Martínez-Sellés M, Datino T, Figueiras-Graillet L, et al.
Study designRandomized controlled trial
SubjectHuman
Abstract
cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。
MeSH
AdolescentAdultAnalysis of VarianceArea Under CurveArrhythmias, CardiacBiotransformationCaffeineChi-Square DistributionCross-Over StudiesCytochrome P-450 CYP1A2Drug InteractionsElectrocardiographyFastingFemaleFood-Drug InteractionsHalf-LifeHeadacheHeart RateHematologic AgentsHumansHydroxylationIntestinal AbsorptionLondonMaleMetabolic Clearance RatePostprandial PeriodQuinazolinesYoung Adult