Branched-chain amino acid transaminase 1 (BCAT1) promotes the growth of breast cancer cells through improving mTOR-mediated mitochondrial biogenesis and function.

Biochemical and biophysical research communications2017Zhang L, Han J

Study designOther primary literature

SubjectHuman

Abstract

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MeSH

AMP-Activated Protein KinasesAdenosine TriphosphateAmino Acids, Branched-ChainBreast NeoplasmsCarcinomaCell Line, TumorCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansMCF-7 CellsMitochondriaOrganelle BiogenesisRNA, Small InterferingReactive Oxygen SpeciesSignal TransductionSirtuin 1TOR Serine-Threonine KinasesTransaminases

DOI 10.1016/j.bbrc.2017.02.101

PMID 28235484

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