Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression.

Cell metabolism2019Ericksen RE, Lim SL, McDonnell E, et al.

Study designOther primary literature

SubjectHuman & animal

Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

AgedAged, 80 and overAmino Acids, Branched-ChainAnimalsCarcinogenesisCarcinoma, HepatocellularCell ProliferationCohort StudiesDisease Models, AnimalDisease ProgressionDown-RegulationFemaleHep G2 CellsHumansLiver NeoplasmsMaleMechanistic Target of Rapamycin Complex 1MiceMice, Inbred C57BLMiddle AgedRatsRats, Inbred ACI

DOI 10.1016/j.cmet.2018.12.020

PMID 30661928

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