Gut microbiota-driven BCAA biosynthesis via Staphylococcus aureus -expressed acetolactate synthase impairs glycemic control in type 2 diabetes in South China.

Microbiological research2025Liang T, Jiang T, Liang Z, et al.

Study designOther primary literature

SubjectHuman & animal

Abstract

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MeSH

Acetolactate SynthaseAmino Acids, Branched-ChainAnimalsBlood GlucoseChinaDiabetes Mellitus, Type 2FecesFemaleGastrointestinal MicrobiomeGlycemic ControlHumansInsulinInsulin ResistanceMaleMetabolomicsMetagenomicsMiceMiddle AgedPrediabetic StateStaphylococcal InfectionsStaphylococcus aureus

DOI 10.1016/j.micres.2025.128145

PMID 40138872

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