BCKDK modification enhances the anticancer efficacy of CAR-T cells by reprogramming branched chain amino acid metabolism.

Molecular therapy : the journal of the American Society of Gene Therapy2024Yang Q, Yang Q, Zhu X, et al.

Study designOther primary literature

SubjectHuman & animal

Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

Amino Acids, Branched-ChainAnimalsCell Line, TumorDisease Models, AnimalHumansImmunotherapy, AdoptiveMiceNeoplasmsReceptors, Chimeric AntigenT-LymphocytesTumor MicroenvironmentXenograft Model Antitumor Assays

DOI 10.1016/j.ymthe.2024.05.017

PMID 38734897

View source →