N-hydroxylation of the antiprotozoal drug pentamidine catalyzed by rabbit liver cytochrome P-450 2C3 or human liver microsomes, microsomal retroreduction, and further oxidative transformation of the formed amidoximes. Possible relationship to the biological oxidation of arginine to NG-hydroxyarginine, citrulline, and nitric oxide.
Study designOther primary literature
SubjectHuman & animal
Record checks
- Study design
- Other primary literature
- Subject
- Human & animal
- Publication year
- 1994
- Source
- doi.org
- Abstract display
- Not reproduced here
- Publication status
- Active
- Status checked
- 17 Aug 2026
- Collected
- 3 Aug 2026
- Freshness
- Current
- Review stage
- Automated
- Record status
- Published
Abstract
cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。
MeSH
DOI 10.1016/s0090-9556(25)08402-8
PMID 8070328
View source →