Nitric oxide synthase inhibitors that interact with both heme propionate and tetrahydrobiopterin show high isoform selectivity.

Journal of medicinal chemistry2014Kang S, Tang W, Li H, et al.

Study designOther primary literature

SubjectHuman

Abstract

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MeSH

BiopterinsEnzyme InhibitorsHemeHumansNitric Oxide SynthaseNitric Oxide Synthase Type INitric Oxide Synthase Type IINitric Oxide Synthase Type IIIStructure-Activity Relationship

DOI 10.1021/jm5004182

PMID 24758147

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