Decreased non-neurogenic acetylcholine in bone marrow triggers age-related defective stem/progenitor cell homing.

Nature communications2025Morikawa T, Fujita S, Sugiura Y, et al.

Study designOther primary literature

SubjectHuman & animal

Abstract

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MeSH

AcetylcholineAgingAnimalsBone MarrowBone Marrow CellsCell MovementFemaleHematopoietic Stem Cell TransplantationHematopoietic Stem CellsHumansIon ChannelsMaleMiceMice, Inbred C57BLNitric OxideNitric Oxide Synthase Type IIIReceptors, NicotinicSignal Transduction

DOI 10.1038/s41467-025-60515-9

PMID 40593589

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