Multi-omic profiling of sarcopenia identifies disrupted branched-chain amino acid catabolism as a causal mechanism and therapeutic target.

Nature aging2025Zuo X, Zhao R, Wu M, et al.

Study designOther primary literature

SubjectHuman & animal

Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

AgedAgingAmino Acids, Branched-ChainAnimalsDisease Models, AnimalFemaleHumansMaleMiceMice, Inbred C57BLMultiomicsMuscle StrengthMuscle, SkeletalSarcopeniaSignal TransductionTOR Serine-Threonine Kinases

DOI 10.1038/s43587-024-00797-8

PMID 39910243

View source →