Glucose-dependent insulinotropic polypeptide/glucagon-like peptide 1 receptor agonist tirzepatide promotes branched chain amino acid catabolism to prevent myocardial infarction in non-diabetic mice.
Cardiovascular research2025Chen M, Zhao N, Shi W, et al.
Study designOther primary literature
SubjectAnimal
Abstract
cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。
MeSH
3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)Amino Acids, Branched-ChainAnimalsDisease Models, AnimalEnergy MetabolismFibrosisGastric Inhibitory PolypeptideGlucagon-Like Peptide-1 ReceptorGlucagon-Like Peptide-1 Receptor AgonistsIncretinsMaleMice, Inbred C57BLMolecular Docking SimulationMyocardial InfarctionMyocytes, CardiacSignal TransductionTOR Serine-Threonine KinasesTirzepatideVentricular Function, Left