Menopause-induced 17β-estradiol and progesterone loss increases senescence markers, matrix disassembly and degeneration in mouse cartilage.

Nature aging2025Gilmer G, Iijima H, Hettinger ZR, et al.

Study designOther primary literature

SubjectHuman & animal

Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

AnimalsBiomarkersCartilageCartilage, ArticularCellular SenescenceChondrocytesDisease Models, AnimalEstradiolExtracellular MatrixFemaleHumansMaleMenopauseMiceMice, Inbred C57BLOsteoarthritis, KneeProgesterone

DOI 10.1038/s43587-024-00773-2

PMID 39820791

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