Epigenetic silencing of argininosuccinate synthetase confers resistance to platinum-induced cell death but collateral sensitivity to arginine auxotrophy in ovarian cancer.

International journal of cancer2009Nicholson LJ, Smith PR, Hiller L, et al.

Study designOther primary literature

SubjectHuman

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Study design: Other primary literature
Subject: Human
Publication year: 2009
Source: doi.org
Abstract display: Not reproduced here
Publication status: Active
Status checked: 17 Aug 2026
Collected: 13 Aug 2026
Freshness: Current
Review stage: Automated
Record status: Published

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Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

Antineoplastic Combined Chemotherapy ProtocolsArginineArgininosuccinate SynthaseCarboplatinCell DeathCisplatinCystadenocarcinoma, SerousDNA MethylationDrug Resistance, NeoplasmFemaleGene Expression Regulation, NeoplasticGene SilencingHumansImmunoblottingMiddle AgedOvarian NeoplasmsPaclitaxelPromoter Regions, GeneticSurvival RateTumor Cells, Cultured

DOI 10.1002/ijc.24546

PMID 19533750

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