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Arginine Deprivation Therapy in Cancer

Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy.

Proceedings of the National Academy of Sciences of the United States of America2014Changou CA, Chen YR, Xing L, et al.

Scholarly article — Journal Article / Research Support, N.I.H., Extramural / Research Support, Non-U.S. Gov't / Research Support, U.S. Gov't, Non-P.H.S. / research-article

Study designOther literature / records
SubjectHuman

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Study design
Other literature / records
Subject
Human
Publication year
2014
Source
doi.org
Abstract display
Not reproduced here
Publication status
Active
Status checked
17 Aug 2026
Collected
13 Aug 2026
Freshness
Current
Review stage
Automated
Record status
Published

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Abstract

The abstract is not reproduced here. Please consult the original source.

MeSH

Antineoplastic AgentsArginineArgininosuccinate SynthaseAutophagyCell DeathCell Line, TumorChromatinDNA, NeoplasmHumansHydrolasesMaleMembrane Potential, MitochondrialMicroscopy, Electron, TransmissionMitochondriaNuclear EnvelopePolyethylene GlycolsProstatic NeoplasmsReactive Oxygen Species

DOI 10.1073/pnas.1404171111

PMID 25122679

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