Oncogenic KRAS Induces Arginine Auxotrophy and Confers a Therapeutic Vulnerability to SLC7A1 Inhibition in Non-Small Cell Lung Cancer.

Cancer research2024Gai X, Liu Y, Lan X, et al.

Study designOther primary literature

SubjectHuman & animal

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Study design: Other primary literature
Subject: Human & animal
Publication year: 2024
Source: doi.org
Abstract display: Not reproduced here
Publication status: Active
Status checked: 17 Aug 2026
Collected: 13 Aug 2026
Freshness: Current
Review stage: Automated
Record status: Published

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Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

AnimalsArginineArgininosuccinate SynthaseCarcinoma, Non-Small-Cell LungCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansLarge Neutral Amino Acid-Transporter 1Lung NeoplasmsMiceProto-Oncogene Proteins p21(ras)Xenograft Model Antitumor Assays

DOI 10.1158/0008-5472.can-23-2095

PMID 38502865

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