Oncogenic KRAS Induces Arginine Auxotrophy and Confers a Therapeutic Vulnerability to SLC7A1 Inhibition in Non-Small Cell Lung Cancer.

Cancer research2024Gai X, Liu Y, Lan X, et al.

Scholarly article — Journal Article / Research Support, Non-U.S. Gov't

Study designOther literature / records

SubjectHuman & animal

Record checks

Study design: Other literature / records
Subject: Human & animal
Publication year: 2024
Source: doi.org
Abstract display: Not reproduced here
Publication status: Active
Status checked: 17 Aug 2026
Collected: 13 Aug 2026
Freshness: Current
Review stage: Automated
Record status: Published

How to read this record →

Abstract

The abstract is not reproduced here. Please consult the original source.

MeSH

AnimalsArginineArgininosuccinate SynthaseCarcinoma, Non-Small-Cell LungCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansLarge Neutral Amino Acid-Transporter 1Lung NeoplasmsMiceProto-Oncogene Proteins p21(ras)Xenograft Model Antitumor Assays

DOI 10.1158/0008-5472.can-23-2095

PMID 38502865

View source →