Pharmacokinetic Properties of Ibuprofen (IBU) From the Fixed-Dose Combination IBU/Caffeine (400/100 mg; FDC) in Comparison With 400 mg IBU as Acid or Lysinate Under Fasted and Fed Conditions-Data From 2 Single-Center, Single-Dose, Randomized Crossover Studies in Healthy Volunteers.

Clinical pharmacology in drug development2019Weiser T, Schepers C, Mück T, et al.

研究デザインランダム化比較試験

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MeSH

AdultArea Under CurveCaffeineCross-Over StudiesFastingFemaleFoodFood-Drug InteractionsHealthy VolunteersHumansIbuprofenLysineMaleMiddle AgedPostprandial PeriodYoung Adult

DOI 10.1002/cpdd.672

PMID 30897305

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