Application of a Physiologically Based Pharmacokinetic Model to Study Theophylline Metabolism and Its Interactions With Ciprofloxacin and Caffeine.

CPT: pharmacometrics & systems pharmacology2016Navid A, Ng DM, Wong SE, et al.

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MeSH

AdultAge FactorsAgedAged, 80 and overBronchodilator AgentsCaffeineCiprofloxacinComputer SimulationDose-Response Relationship, DrugDrug Dosage CalculationsDrug InteractionsFemaleHumansMaleMiddle AgedModels, BiologicalPrecision MedicineSex FactorsTheophylline

DOI 10.1002/psp4.12061

PMID 26933518

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