Increased susceptibility to metabolic dysregulation in a mouse model of Alzheimer's disease is associated with impaired hypothalamic insulin signaling and elevated BCAA levels.
Alzheimer's & dementia : the journal of the Alzheimer's Association2016Ruiz HH, Chi T, Shin AC, et al.
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MeSH
Alzheimer DiseaseAmino Acids, Branched-ChainAmyloid beta-Protein PrecursorAnimalsBody WeightDiet, High-FatDisease Models, AnimalEatingGene Expression RegulationHumansHypothalamusInsulinInsulin ResistanceMaleMetabolic DiseasesMiceMice, TransgenicMutationPresenilin-1Signal TransductionTriglycerides
DOI 10.1016/j.jalz.2016.01.008
PMID 26928090
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