Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme.

Biochemistry2001Okada K, Hirotsu K, Hayashi H, et al.

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MeSH

BacillusBinding SitesComputer SimulationConserved SequenceCrystallography, X-RayD-Alanine TransaminaseEscherichia coliIminesKeto AcidsLeucineLigandsModels, MolecularProtein ConformationProtein Structure, TertiaryStructure-Activity RelationshipSubstrate SpecificityTransaminases

DOI 10.1021/bi010384l

PMID 11412098

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