Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.
Science (New York, N.Y.)2016Mayers JR, Torrence ME, Danai LV, et al.
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MeSH
Amino Acids, Branched-ChainAnimalsCarcinoma, Non-Small-Cell LungCarcinoma, Pancreatic DuctalGene Expression Regulation, NeoplasticHumansLung NeoplasmsMaleMetabolic Networks and PathwaysMiceMice, Inbred C57BLMinor Histocompatibility AntigensMutationNitrogenOrgan SpecificityPancreatic NeoplasmsPregnancy ProteinsProto-Oncogene Proteins p21(ras)Transaminases
DOI 10.1126/science.aaf5171
PMID 27609895
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