Chronic Co-Administration of Sepiapterin and L-Citrulline Ameliorates Diabetic Cardiomyopathy and Myocardial Ischemia/Reperfusion Injury in Obese Type 2 Diabetic Mice.
Circulation. Heart failure2016Baumgardt SL, Paterson M, Leucker TM, et al.
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MeSH
Age FactorsAnimalsBiopterinsCardiotonic AgentsCells, CulturedCitrullineCoronary CirculationCoronary VesselsDiabetes Mellitus, Type 2Diabetic CardiomyopathiesDisease Models, AnimalDrug Administration ScheduleDrug Therapy, CombinationEndothelial CellsIsolated Heart PreparationMice, Inbred C57BLMice, ObeseMyocardial InfarctionMyocardial Reperfusion InjuryMyocardiumNitric OxideNitric Oxide Synthase Type IIIObesityPhosphorylationProtein MultimerizationPterinsTime FactorsVasodilationVentricular Function, Left
DOI 10.1161/circheartfailure.115.002424
PMID 26763290
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