Anti-Inflammatory Modified Fuzi Decoction Antagonizes Synovial TNF-α/TRAF2/NF-κB Signaling to Remedy Osteoarthritis.
Drug design, development and therapy2025Wang Y, Ren J, Chen H, et al.
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MeSH
AnimalsAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalArthritis, ExperimentalCells, CulturedDisease Models, AnimalDose-Response Relationship, DrugDrugs, Chinese HerbalIodoacetic AcidMaleNF-kappa BOsteoarthritisRatsRats, Sprague-DawleySignal TransductionStructure-Activity RelationshipSynovial MembraneTNF Receptor-Associated Factor 2Tandem Mass SpectrometryTumor Necrosis Factor-alpha