Cytotoxicity of activated rat macrophages against syngeneic islet cells is arginine-dependent, correlates with citrulline and nitrite concentrations and is identical to lysis by the nitric oxide donor nitroprusside.

Diabetologia1993Kröncke KD, Rodriguez ML, Kolb H, et al.

Study designOther primary literature

SubjectAnimal

Abstract

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MeSH

1-Methyl-3-isobutylxanthineAnimalsArginineCells, CulturedCitrullineCyclic GMPFemaleIslets of LangerhansKineticsMacrophage ActivationMacrophagesMaleNitric OxideNitritesNitroprussideRatsRats, WistarThionucleotidesomega-N-Methylarginine

DOI 10.1007/bf00399088

PMID 7679656

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