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Prolonged high-dose prenatal caffeine exposure induces organ-specific developmental toxicity: renal p53 downregulation and hepatic caspase-3 upregulation in neonatal mice, supported with in silico studies.

Naunyn-Schmiedeberg's archives of pharmacology2026Said A, Diab AA, Safwat G, et al.
Study designOther primary literature
SubjectAnimal

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Study design
Other primary literature
Subject
Animal
Publication year
2026
Source
doi.org
Abstract display
Not reproduced here
Publication status
Active
Status checked
17 Aug 2026
Collected
3 Aug 2026
Freshness
Current
Review stage
Automated
Record status
Published

Abstract

cc by 以外(cc by-nc / cc by-nc-nd / NONE 等)は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

AnimalsAnimals, NewbornApoptosisCaffeineCaspase 3Computer SimulationDown-RegulationFemaleKidneyLiverMaleMicePregnancyPrenatal Exposure Delayed EffectsTumor Suppressor Protein p53Up-Regulation

DOI 10.1007/s00210-026-05406-6

PMID 42115392

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