Static Stretching Acutely Reduces the Ergogenic Effects of Caffeine on Sprint Performance but Not Maximal Ball Velocity in Football Players.Randomized controlled trialHumanActiveEuropean journal of sport science2026
Çabuk R, İslamoğlu İ, Demirarar O, et al.
The Effect of CYP1A2 Gene Polymorphisms on Caffeine Pharmacokinetics and Exercise Performance in Male Recreational Athletes.Randomized controlled trialHumanActiveEuropean journal of sport science2026
Masters C, Ali A, Badenhorst C, et al.
Caffeine Consumption Pattern and Associated Side Effects and Withdrawal Syndromes Among University Students of Bangladesh.Other primary literatureUnknownActiveHealth science reports2026
Rimu IJ, Islam MT, Mim HA, et al.
Physiologically Based Pharmacokinetic Modeling of Caffeine in Preterm Neonates: Influence of Renal Function and Impairment on Dosing.Other primary literatureHumanActiveJournal of clinical pharmacology2026
Thomas N, Harer MW, Lim SY
Caffeine Supplementation Enhances Aged Human Oocyte Quality and Embryo Development in In Vitro Fertilization: A Retrospective Paired Study.Other primary literatureUnknownActiveReproductive medicine and biology2026
Ha J, Kim S, Jang H, et al.
Prolonged high-dose prenatal caffeine exposure induces organ-specific developmental toxicity: renal p53 downregulation and hepatic caspase-3 upregulation in neonatal mice, supported with in silico studies.Other primary literatureAnimalActiveNaunyn-Schmiedeberg's archives of pharmacology2026
Said A, Diab AA, Safwat G, et al.
Effects of caffeine and acute exercise on the validity of a submaximal cycle ergometer test: a randomised, placebo-controlled crossover study.Randomized controlled trialHumanActiveEuropean journal of applied physiology2026
Björkman F, Engström J, Helge T, et al.
High versus standard dose caffeine in prevention of apnea of prematurity: an assessor-blinded randomized controlled trial (HI-CAF trial).Randomized controlled trialHumanActiveEuropean journal of pediatrics2026
M N A, Nanda D, Das RK, et al.
Caffeine Sodium Benzoate-Induced Macrophage M1 Polarization Promotes Endothelial Progenitor Cell Dysfunction by Inducing Mitochondrial Dysfunction Via Targeting let-7a-5p/OPA1 Axis.Other primary literatureHuman & animalActiveApplied biochemistry and biotechnology2026
Yu T, Yuan Y, Suo F, et al.
Serial determination of caffeine and active metabolites in a case of severe caffeine poisoning causing recurrent cardiac arrest after hemodialysis: a case report.Other primary literatureUnknownActiveForensic science, medicine, and pathology2026
Kohara S, Kamijo Y, Kyan R, et al.
Evaluation of continuous renal replacement therapy efficacy in severe caffeine intoxication: concentration-dependent variation in caffeine clearance.Other primary literatureHumanActiveCEN case reports2026
Takeda S, Chiba H, Yamazaki T, et al.
Ups and downs in the experimental treatment of murine typhoid fever using gentamicin combined with caffeine.Other primary literatureAnimalActiveBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2026
de Souza Silva E, Dos Santos Rocha RT, da Silva JNG, et al.
Effect of high caffeine exposure on longitudinal bone growth during puberty in immature female rats.Other primary literatureUnknownActiveToxicological research2026
Keum J, Choi Y, Ryu KY, et al.
Association between academic stress and caffeine expectancy among medical students in Jeddah Saudi Arabia.Other primary literatureUnknownActiveDiscover mental health2026
El-Zayat A, Sultan S, Sarhan R, et al.
Chronic environmental caffeine exposure induces gut transcriptomic reprogramming in zebrafish.Other primary literatureAnimalActiveAquatic toxicology (Amsterdam, Netherlands)2026
Wong J, Chan N, Sun F, et al.
Biosensor for caffeine detection using Drosophila gustatory receptor-derived peptide.Other primary literatureHuman & animalActiveBiosensors & bioelectronics2026
Wang Z, Liu W, Yu Q, et al.
PDE4B-associated regulation of placental HSD11B2 in fetal growth restriction in a prenatal caffeine exposure model.Other primary literatureUnknownActiveChemico-biological interactions2026
Cao X, Jiang P, Yu L, et al.
Advancing precision treatment in preterm infants: Population pharmacokinetics of caffeine for apnea of prematurity.Observational studyHumanActiveDrug metabolism and disposition: the biological fate of chemicals2026
He Y, Shen X, Wong S, et al.
Randomized controlled trial of a remote-guided caffeine reduction intervention.Randomized controlled trialHumanActiveDrug and alcohol dependence2026
Knerr AW, Strickland JC, Labos BH, et al.
Caffeine-mediated cytotoxicity of snortable energy powders in human nasal epithelial cells under air-liquid interface conditions.Other primary literatureHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2026
Mercier C, Rouabah L, Pourchez J
Ecological risk assessment of caffeine in global aquatic ecosystems: From land to sea.Other primary literatureUnknownActiveJournal of hazardous materials2026
Fan B, Guo X, Zhao B, et al.
Impact of caffeine dose on bone healing with tricalcium silicate in a rat tibial defect model.Other primary literatureAnimalActiveJournal of stomatology, oral and maxillofacial surgery2026
Kaya B, Ocak MS, Dündar S, et al.
Prenatal caffeine exposure impairs neurodevelopment via glucocorticoid-driven epigenetic cascade suppressing astrocytic ABCG1 and cholesterol transport.Other primary literatureAnimalActiveMetabolism: clinical and experimental2026
Dai G, Luo M, Dai S, et al.
Efficacy of caffeine supplementation on fatigue in patients with multiple sclerosis: A randomized double-blind placebo-controlled trial.Randomized controlled trialHumanActiveMultiple sclerosis and related disorders2026
Baghbanian SM, Gharanjik A, Ghazaeian M, et al.
Caffeine Citrate does not reduce brain injury following inflammation-amplified hypoxia ischaemia or hypoxia ischaemia in the Newborn Piglet Model.Other primary literatureAnimalActiveNeuropharmacology2026
Maple G, Meehan C, d'Angelo I, et al.
Caffeine attenuates anxiety- and depressive-like behavior following cyclosporine administration in mice, possibly via an NO pathway.Other primary literatureAnimalActivePhysiology & behavior2026
Ebrahimi-Ghiri M, Khakpai F, Alijanpour S, et al.
A Green Approach to the Simultaneous Detection of Vitamin C, Paracetamol, and Caffeine Using an Aspartic Acid-Modified Waste Battery Electrode.Other primary literatureUnknownActiveACS omega2026
Motin MA, Hasanuzzaman M, Mia MAH, et al.
Theoretical Investigation of the Adsorption Behavior of Caffeine, Nicotine, and Dopamine Molecules Using 2D Monolayers.Other primary literatureUnknownActiveACS omega2026
Feng CL, Luo X
Layered ZnO/MgO Nanohybrids for Photocatalytic Caffeine Degradation.Other primary literatureUnknownActiveACS omega2026
Brazuna LP, Rubim BSG, Bacani R, et al.
AI-Guided <i>De Novo</i> Design of a Caffeine-Induced Protein Dissociation System.Other primary literatureHumanActiveJournal of the American Chemical Society2026
Nonomura T, McKee B, Price A, et al.
Caffeine for the prevention of acute kidney injury in neonates: a systematic review and meta-analysis.ReviewUnknownActiveJournal of perinatology : official journal of the California Perinatal Association2026
Kobayashi R, Nagao E, Hirano D, et al.
Dietary caffeine to assess CYP1A2 activity, tailor clozapine doses, and predict treatment response: genetic, epigenetic and clinical analyses.Other primary literatureHumanActiveMolecular psychiatry2026
Laaboub N, Vandenberghe F, Ansermot N, et al.
Caffeine and preterm infants: multiorgan effects and therapeutic creep: scope to optimise dose and timing.ReviewHumanActivePediatric research2026
O'Shea M, Butler L, Holohan S, et al.
Caffeine prevents airway hyperreactivity in a neonatal mouse model of continuous positive airway pressure.Other primary literatureUnknownActivePediatric research2026
Rungsiyaphornratana P, Mayer CA, McAllister S, et al.
Development of engineered magnetic liposome/exosome hybrid as a novel caffeine nanocarrier for restraining liver fibrosis induced in rats.Other primary literatureAnimalActiveScientific reports2026
Elakkad YE, Refai H, Ahmed HH, et al.
Occurrence and concentration of caffeine and cadmium as micropollutants in the Red Sea coast, Egypt.Other primary literatureUnknownActiveScientific reports2026
El-Sokkary SG, Abd El-Wakeil KF, Obuid-Allah AH
A green fabrication of pharmacologically relevant fused pyrimidines using recyclable caffeine-H<sub>3</sub>PO<sub>4</sub> catalyst: insight into antibacterial and cytotoxic efficacy.Other primary literatureUnknownActiveRSC advances2026
Bhatnagar A, Rai N, Singh NA, et al.
Paper-based electrochemical sensor for direct detection of caffeine in commercial beverage samples.Other primary literatureUnknownActiveRSC advances2026
Syahputra MY, Shinchi E, Shida K, et al.
Comparative effects of caffeine and paraxanthine on rowing performance and sleep quality: a randomized crossover study.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2026
Bingol Diedhiou A, Yildirim UC, Ozdenk S, et al.
Soccer pass performance following caffeine intake with deliberate or maintenance practice.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2026
Yaşlı BÇ, Esen Ö, Önlü AŞ, et al.
Effects of different caffeine doses on fat oxidation and cardiovascular response during exercise at FATmax in overweight/obese female college students.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2026
Gong Z, Yu S, Lyu Z, et al.
Effects of acute caffeine ingestion combined with post-activation potentiation enhancement on the anaerobic capacity of male collegiate basketball players.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2026
Ma Y, He T, Li H, et al.
Effects of caffeine gum on same-day and subsequent neuromuscular performance under a standardized resistance-priming condition in male basketball players.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2026
Wang J, Li B, Huang Y, et al.
Caffeine makes a splash: a systematic review and multilevel meta-analysis exploring the effects of caffeine intake on swimming performance.Meta-analysisHumanActiveJournal of the International Society of Sports Nutrition2026
Wang Z, Qiu B, Bao J, et al.
Caffeine clearance in severe intoxication: a comparative case series of hemodialysis, hemoadsorption, and continuous kidney replacement therapy.Other primary literatureHumanActiveClinical toxicology (Philadelphia, Pa.)2026
Izutani Y, Nakamura A, Yamasaki S, et al.
Caffeine levels and voluntary labelling accuracy of guarana-containing solid foods in Korea: A pre-implementation market baseline (2020-2021).Other primary literatureUnknownActiveFood additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment2026
Lee I, Jung S, Chang M, et al.
Evaluating the effectiveness of caffeine-based baits against two pest ant species.Other primary literatureAnimalActiveJournal of economic entomology2026
Lee CC, Lin PC, Lin CC
Acute Myocardial Ischemia Secondary to Coronary Vasospasm From Long-Term High-Dose Caffeine Consumption.Other primary literatureHumanActiveMilitary medicine2026
Corcillo J, Murray BP, DeFlorio P
Exploiting conformational changes in a caffeine aptamer to engineer synthetic RNA devices.Other primary literatureAnimalActiveNucleic acids research2026
Kraus L, Gunawan VJ, Johannson R, et al.
Association between caffeine intake and constipation in a U.S. population aged 20 to 65 years: Results from NHANES 2007 to 2010.Other primary literatureHumanActiveMedicine2026
Li H, Wang H
Periconceptual Caffeine Intake and Adverse Pregnancy Outcomes: Results From the nuMoM2b Cohort.Other primary literatureHumanActiveBJOG : an international journal of obstetrics and gynaecology2026
Ruderman RS, Freedman AA, Suresh SC
Caffeine Was Associated With Shorter Continuous Positive Airway Pressure Treatment for Infants up to Eight Weeks Old Hospitalised for Bronchiolitis.Observational studyHumanActiveActa paediatrica (Oslo, Norway : 1992)2026
Casabianca M, Akouka D, Maman L, et al.
Feasibility of dried blood spot collection for caffeine pharmacokinetic studies in microgravity: Insights from parabolic flight campaigns.Other primary literatureHumanActiveBritish journal of clinical pharmacology2026
Derobertmasure A, Toh LS, Verstuyft C, et al.
Integrative Computational and Experimental Approaches Reveal the Protective Role of Moderate Caffeine Intake Against Apical Periodontitis Induced Bone Loss.Other primary literatureAnimalActiveInternational endodontic journal2026
Rodrigues MFL, Frazão DR, Souza-Monteiro D, et al.
Exploring the Relationship Between Caffeine Consumption, Caffeine Metabolism, and Sleep Behaviours: A Mendelian Randomisation Study.Other primary literatureHumanActiveJournal of sleep research2026
Das NR, Woolf B, Page S, et al.
CYP1A2 Genotype and the Ergogenic Effect of Acute Caffeine Intake on Muscular Strength and Endurance Performance in Trained Individuals.Randomized controlled trialHumanActiveScandinavian journal of medicine & science in sports2026
Montalvo-Alonso JJ, Del Val-Manzano M, Martín-Rivas I, et al.
Intermittent hypoxia and caffeine in infants born preterm: the ICAF Randomized Clinical Trial.Randomized controlled trialHumanActiveArchives of disease in childhood. Fetal and neonatal edition2026
Eichenwald E, Corwin M, McEntire B, et al.
Dosing practices of caffeine therapy for apnoea of prematurity: a retrospective single-centre observational study.Observational studyHumanActiveBMJ paediatrics open2026
Fatunla OAT, Zandvoort CS, Robinson S, et al.
Characterization of cardiac disease-associated mutations in RyR2 Ca<sup>2+</sup>- and caffeine-binding sites.Other primary literatureHuman & animalActiveAmerican journal of physiology. Cell physiology2026
Chirasani VR, Patwardhan A, Yamaguchi N
Mixed Movement Disorder Caused by <i>ADCY5</i> Pathogenic Variant Successfully Treated With Caffeine: A Case From Ukraine.Other primary literatureUnknownActiveCase reports in neurological medicine2026
Tsoma E, Studeniak T, Jech R, et al.
Caffeine as a Treatment for Perinatal Hypoxic-Ischemic Brain Injury: The Potential Risks and Benefits.ReviewHuman & animalCorrectedDevelopmental neuroscience2026
Zhou KQ, Lam F, Bennet L, et al.
Caffeine Addiction: Patterns and Prevenance Among Undergraduate Medical and Engineering Students in Southern India.Other primary literatureUnknownActivePsychological reports2026
Muppa J, Kavi A, Oruganti A, et al.
Roland R. Griffiths, psychopharmacology pioneer: Abuse liability, alcohol, nicotine, caffeine, benzodiazepines, and psychedelics.ReviewHuman & animalActiveJournal of psychopharmacology (Oxford, England)2026
Henningfield JE, Barrett FS, Evans SM, et al.
The impact of caffeine consumption on migraine: a systematic review.Systematic reviewHumanActiveBMC neurology2026
Makhlouf HA, Khelifa H, Batarseh SF, et al.
Effects of a caffeine-based diet on insecticide resistance and longevity in infected Anopheles coluzzii.Other primary literatureAnimalActiveParasites & vectors2026
Cissé-Niambélé K, Koella JC, Hien DFS, et al.
Caffeine treatment for apnea in infants and children: protocol for a systematic review and meta-analysis.Other primary literatureUnknownActiveSystematic reviews2026
Yu M, Sharifi H, Quon S, et al.
Caffeine intake from different dietary sources and its association with sleep quality in employed adults.Other primary literatureUnknownActiveBMC nutrition2026
Toprak K, Yildirim Z, Ayyildiz F
Unraveling the complexities of caffeine: metabolism, genetics, evolution, and health.ReviewHuman & animalActiveHereditas2026
Liu X, Xu S
Caffeine before cesarean delivery: a novel preventive strategy against spinal hypotension, a double blind placebo-controlled trial.Other primary literatureUnknownActiveJournal of anesthesia, analgesia and critical care2026
Helmy MA, Helmy KA, Zaki RM, et al.
Caffeine Overdose-Induced Diabetic Ketoacidosis With Gastrointestinal Injury in Undiagnosed Type 2 Diabetes.Other primary literatureUnknownActiveJCEM case reports2026
Kohmoto H, Uotsu S, Masaoka T, et al.
Caffeine ingestion improves morning neuromuscular performance to evening levels in healthy females.Other primary literatureHumanActivePloS one2026
Singh A, Hesketh SJ
Caffeine potentiates the dependence induced by central nervous system depressants contained in over-the-counter medications in mice.Other primary literatureAnimalActiveThe Journal of toxicological sciences2026
Yonemura-Hirata A, Kaizaki-Mitsumoto A, Numazawa S
Characterization and Cytotoxicity of West Java Coffee Extracts, Chlorogenic Acid, Caffeine on MDA-MB-231, MCF-7 Cell Lines, and Their Impact on <i>MYC</i> and <i>AXIN2</i> Wnt Pathway Gene Expression.Other primary literatureUnknownActiveBreast cancer (Dove Medical Press)2026
Aborziza M, Zuhrotun A, Novianto A, et al.
Calcium Carbonate-Stabilized Nano-Caffeine Emulsion Attenuates Diabetic Cardiomyopathy via Antioxidant, Anti-Inflammatory, and Anti-Fibrotic Pathways in Type 2 Diabetic Rats with HPLC-Quantified Cardiac Caffeine Levels.Other primary literatureAnimalActiveInternational journal of nanomedicine2026
Mansouri RA, Aboubakr EM, Alshaibi HF, et al.
Caffeine impairs red blood cell storage quality by dual inhibition of ADORA2b signaling and G6PD activity.Other primary literatureHuman & animalActiveHaematologica2026
Dzieciatkowska M, Hay A, Issaian A, et al.
Both acute and chronic caffeine consumption affect cardiovascular responses to total sleep deprivation.Other primary literatureUnknownActiveFrontiers in cardiovascular medicine2026
Mateo L, Tardo-Dino PE, Gomez-Merino D, et al.
Caffeine-mediated CD39<sup>+</sup> Treg activation via the CD39-adenosine receptor pathway is a novel risk factor for pulmonary tuberculosis.Other primary literatureHuman & animalActiveFrontiers in immunology2026
Zhu L, Zheng Z, Huang X, et al.
Clinical and biological impact of caffeine therapy in premature infants with apnea of prematurity: a prospective observational study.Other primary literatureUnknownActiveFrontiers in medicine2026
Neamțu AV, Zlatian OM, Bălășoiu AT, et al.
Caffeine attenuates cisplatin induced microglial reactivity and cognitive dysfunction.Other primary literatureUnknownActiveFrontiers in molecular neuroscience2026
Oliveros A, Loncar I, Mostafa M, et al.
A systematic review and meta-analysis of the evidence on the acute effects of caffeine on sport-specific skills, physical performance, and physiological function in female basketball players.Systematic reviewUnknownActiveFrontiers in nutrition2026
Zhang Z, Yin M, Qiu B, et al.
Examining the relationship between problematic social media use and caffeine use disorder in the context of physical activity: a cross-sectional moderation study among university students.Other primary literatureUnknownActiveFrontiers in nutrition2026
Orhan BE, Karadağ B, Alkasasbeh WJ, et al.
Effects of acute caffeine supplementation on physical, physiological, and sport-specific performance in female volleyball players: a systematic review and three-level meta-analysis.Systematic reviewUnknownActiveFrontiers in nutrition2026
Zhang Z, Wang Y, Lu Z, et al.
Brain activity as a candidate biomarker for personalised caffeine treatment in premature neonates.Other primary literatureUnknownActiveFrontiers in pediatrics2026
Usman F, Zandvoort CS, Robinson S, et al.
Developmental age and clinical illness drive <i>in vivo</i> variability of CYP1A2 ontogeny and caffeine metabolism in preterm neonates.Other primary literatureUnknownActiveFrontiers in pharmacology2026
Wang MC, Sealey VA, Rahman M, et al.
Does acute caffeine ingestion improve high-intensity interval exercise performance? A systematic review and meta-analysis.Systematic reviewUnknownActiveFrontiers in physiology2026
Peng Y, He L, Du W, et al.
Caffeine and human performance: from molecular mechanisms to exercise and recovery.ReviewUnknownActiveFrontiers in physiology2026
Leng J, Yu J, Li Z, et al.
Complete chloroplast genome characterization and phylogenetic analysis of two natural caffeine-free <i>Camellia yungkiangensis</i> H. T. Chang accessions.Other primary literatureUnknownActiveFrontiers in plant science2026
Liang S, Yang C, Mi X, et al.
Design and Synthesis of Caffeine-Based Derivatives with Antioxidant and Neuroprotective Activity: In Vitro Evaluation and SwissADME Profiling.Other primary literatureUnknownActiveAntioxidants (Basel, Switzerland)2026
Stefanova D, Garip A, Tzankova V, et al.
Caffeine Mitigates Adenosine-Mediated Angiogenic Properties of Choroidal Endothelial Cells Through Antagonism of A<sub>1</sub> Adenosine Receptor and PI3K-AKT Axis.Other primary literatureHuman & animalActiveCells2026
Park S, Song YS, Feng X, et al.
Association Between Serum Caffeine Concentrations, Intermittent Hypoxia and Apnea in Preterm Infants: A Prospective Observational Study.Other primary literatureUnknownActiveChildren (Basel, Switzerland)2026
Vardar G, Oguz D, Uslu I, et al.
Modulators of Airway Remodeling: The Role of Caffeine and Calcitriol.Other primary literatureHumanActiveInternational journal of molecular sciences2026
Sobczak M, Wieczfińska J, Pawliczak R
Acute Intoxication with Caffeine-Containing Tablets: A Case Report with a Fatal Outcome.Other primary literatureUnknownActiveJournal of xenobiotics2026
Radeva-Ilieva M, Stoeva-Grigorova S, Yarabanova I, et al.
Caffeine Biotransformation in Zebrafish Larvae: Integrated LC-MS/MS Quantification and FTIR Spatial Mapping.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2026
Bartoszek A, Kozub-Pędrak A, Wielgosz A, et al.
Molecular Insights into the Interaction Between Metformin and Caffeine: The Time-Dependent Antagonism and Modulation of p53 Signaling in Cancer Cells.Other primary literatureHumanActiveMolecules (Basel, Switzerland)2026
Zeljković V, Bogavac M, Dekić M, et al.
From Conventional Methods to Innovation: Caffeine and Chlorogenic Acid Extraction and Quantification in the Rise of Smart and Green Techniques-A Systematic Review.Systematic reviewHumanActiveMolecules (Basel, Switzerland)2026
Awwad SH, Nasereddin LM, Al-Tamimi O, et al.
Glyceryl Trinitrate Enhances Caffeine Cytotoxicity Under Metabolic Stress in Cancer Cells.Other primary literatureHumanActiveMolecules (Basel, Switzerland)2026
Zeljković V, Bogavac M, Soldatović TV, et al.
Effects of Acute and Moderate Caffeine Doses on Sport Climbing Performance: A Randomized Controlled Trial.Randomized controlled trialHumanActiveNutrients2026
Ruiz-López A, Montalvo-Alonso JJ, Martín-Rivas I, et al.
Deceptive Caffeine Shows Limited Impact on Short-Term Neuromuscular Performance.Randomized controlled trialHumanActiveNutrients2026
Valero F, Viudez CJ, Calle S, et al.
Coffee Versus Caffeine as Ergogenic Aids: Biological and Methodological Distinctions with Implications for Exercise Performance and Recovery.ReviewHumanActiveNutrients2026
Domaszewski P
Coffee and Caffeine in Depression: Symptom-Level Modulation and Challenges in Nutripsychiatric Interpretation.ReviewHumanActiveNutrients2026
Turkowska I, Rogowska AM, Konieczny M, et al.
The Caffeinated Brain Part 2: The Effect of Caffeine on Sleep-Related Electroencephalography (EEG)-A Systematic and Mechanistic Review.Systematic reviewHumanActiveNutrients2026
Chmiel J, Kurpas D
Effects of Combined Caffeine and <i>Rhodiola rosea</i> Supplementation on Repeated Aerial Duel Performance and Neck Neuromuscular Function in Soccer Players.Randomized controlled trialHumanActiveNutrients2026
Dou Y, Feng Z, Xu H, et al.
Melatonin, Caffeine, or Their Combination: Effects on Sleep, Performance, Perceived Exertion in a Placebo-Controlled Crossover Study.Randomized controlled trialHumanActiveNutrients2026
Mahdi N, Delleli S, Maaoui KB, et al.
Effects of Dietary Nitrate and Caffeine on End Power and Work Above End Power During a 3 min All-Out Test in Trained Male Cyclists.Randomized controlled trialHumanActiveNutrients2026
Hagele AM, Sunderland KL, Mumford PW, et al.
The Caffeinated Brain Part 1: The Effects of Caffeine on Event-Related Potentials (ERPs)-A Systematic and Mechanistic Review.Systematic reviewHumanActiveNutrients2026
Chmiel J, Malinowska A, Kurpas D
Differential Time-of-Day Effects of Caffeine Capsule and Mouth Rinse on Physical Performance and Volleyball-Specific Skills in Adolescent Male Volleyball Players.Randomized controlled trialHumanActiveNutrients2026
Amor SB, Dhahbi W, Souaifi M, et al.
Dose-Response Effect of Oral Caffeine Use on Aerobic Exercise Performance: A Systematic Review and Meta-Analysis.Meta-analysisHumanActiveNutrients2026
Martins GL, Aparecido JM, Marquezi ML, et al.
Morphological and Chemical Characterization of a Novel Wild Tea Plant Resource with Naturally Low Caffeine and High Theobromine from Guangxi Province, China.Other primary literatureUnknownActivePlants (Basel, Switzerland)2026
Ma Q, Yan Z, Yang X, et al.
Effects of Caffeine on Voluntary Force Estimation During Isometric Exercises.Other primary literatureUnknownActiveSports (Basel, Switzerland)2026
Jiménez-Ormeño E, Giráldez-Costas V, Lara-López B, et al.
Effect of Acute Caffeine Intake on Maximal Aerobic Speed in University Soccer Players Assessed by the 30-15 Intermittent Fitness Test.Other primary literatureUnknownActiveSports (Basel, Switzerland)2026
García-Chaves DC, Fernandez Zapata JP, Oyaga Álvarez T, et al.
Caffeine Exposure Modulates Trophoblast Differentiation and Estradiol Synthesis.Other primary literatureUnknownActiveToxics2026
Keum J, Lee J, Ryu KY, et al.
Caffeine Exposure Alters Neurotransmission and Stress Physiology in a Freshwater Gastropod.Other primary literatureUnknownActiveToxics2026
Mohamed-Benhamu A
Exploring the potential synergistic pharmacological and psychological effects of caffeine on exercise performance: a placebo-balanced study.Other primary literatureUnknownActiveBiology of sport2026
Del Coso J, Lara B, Gallo-Salazar C, et al.
Counteracting Static Stretching-Induced Anaerobic Performance Impairment: The Role of Caffeine.Other primary literatureUnknownActiveJournal of human kinetics2026
Çabuk R, Demirarar O, Arslan H, et al.
External Pharmacokinetic Model Evaluation of Caffeine in Critically Ill Neonates With Heart Disease Using Data Collected From a Pragmatic Platform Trial.Other primary literatureUnknownActiveThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG2026
Hallock C, Hawk A, Castro C, et al.
Effects of Caffeine on NFL Combine-Like Tests in Undergraduate Students.Other primary literatureUnknownActiveInternational journal of exercise science2026
Catalfu KM, Huckabee LA, Simmons BT, et al.
Impact of Energy Drinks and Caffeine on Cognition, Stress, and Sleep During Examination: A Mixed-Methods Cross-Sectional Study From a Medical School in Mauritius.Other primary literatureUnknownActiveCureus2026
Dodia K, Jatain N, Sharma R, et al.
Prediction of severe caffeine intoxication: a bedside clinical model with implications for extracorporeal therapy.Other primary literatureUnknownActiveClinical toxicology (Philadelphia, Pa.)2026
Nakajima Y, Sugita H, Yamaga H, et al.
Extended Caffeine for Apnea in Moderately Preterm Infants: The MoCHA Randomized Clinical Trial.Randomized controlled trialHumanActiveJAMA2025
Carlo WA, Eichenwald EC, Carper BA, et al.
Indications and timings for caffeine initiation in preterm infants.Meta-analysisHumanActiveThe Cochrane database of systematic reviews2025
Borys F, Wróblewska-Seniuk K, Fiander M, et al.
Sex differences in the acute effect of caffeine on repeated sprint performance: A randomized controlled trial.Randomized controlled trialHumanActiveEuropean journal of sport science2025
Pérez-López A, Garriga-Alonso L, Montalvo-Alonso JJ, et al.
The Use of Caffeine Citrate in the Management of Neonatal Apnea in Low- and Middle-Income Countries: A Rapid Systematic Review.ReviewUnknownActiveHealth science reports2025
Amponsah SK, Nartey CM, Ofori EK
Prevalence of a delayed diagnosis of caffeine poisoning in the emergency department of a Japanese hospital.Other primary literatureUnknownActiveJournal of general and family medicine2025
Komagamine J, Kurihara T
Caffeine for Persistent Intermittent Hypoxia in Newborns With and Without Chronic Lung Disease.Other primary literatureHumanActivePediatric pulmonology2025
Côté A, Savanh P, Shalish W, et al.
Caffeine Protects Newborn Rat Lungs Against the Effects of Hyperoxia and Intra-Amniotic Enterotoxin.Other primary literatureAnimalActivePediatric pulmonology2025
Mielgo V, Catozzi C, Ricci F, et al.
Validation of a quantitative liquid chromatography/hybrid quadrupole-linear ion trap MS/MS method for carfentanil and caffeine in a live human epidermis model.Other primary literatureHumanActiveRapid communications in mass spectrometry : RCM2025
Oyler JM, Maistros KJ, Kilgour D
Device for Electrochemical Caffeine Analysis in Fluids (DECAF): A Stir-Bar-Embedded Sensor for Real-Time Caffeine Analysis in Commercial and Homemade Beverages.Other primary literatureUnknownActiveSmall (Weinheim an der Bergstrasse, Germany)2025
Vargas Ramos D, Ma H, Khazaee Nejad S, et al.
[Caffeine intoxication with suicidal intent].Other primary literatureHumanActiveInnere Medizin (Heidelberg, Germany)2025
Uehlein S, Schneider R, Stahl K, et al.
Efficacy of caffeine as an ergogenic aid in multiple cycling time trials.Randomized controlled trialHumanActiveEuropean journal of applied physiology2025
Vinícius Í, Brietzke C, Franco-Alvarenga P, et al.
Acute caffeine intake improves muscular strength, power, and endurance performance, reversing the time-of-day effect regardless of muscle activation level in resistance-trained males: a randomized controlled trial.Randomized controlled trialHumanActiveEuropean journal of applied physiology2025
Montalvo-Alonso JJ, Del Val-Manzano M, Cerezo-Telléz E, et al.
Comprehensive machine learning assessment of zebrafish behaviour and biochemical markers in response to caffeine exposure.Other primary literatureAnimalActiveEcotoxicology (London, England)2025
Teixeira C, Rodrigues S, Amorim J, et al.
Ecotoxicological impacts of caffeine on Daphnia magna: insights from acute to chronic exposures.Other primary literatureAnimalActiveEcotoxicology (London, England)2025
Rodrigues S, Gonçalves C, Golovko O, et al.
Neuroprotective efficacy of berberine and caffeine against rotenone-induced neuroinflammatory and oxidative disturbances associated with Parkinson's disease via inhibiting α-synuclein aggregation and boosting dopamine release.Other primary literatureAnimalActiveInflammopharmacology2025
Waheeb TS, Abdulkader MA, Ghareeb DA, et al.
Caffeine: a potential mechanism for anti-obesity.ReviewHuman & animalActivePurinergic signalling2025
Wang M, Guo W, Chen JF
Development of a simple estimation method of serum caffeine concentration using a point-of-care test kit for urinary caffeine.Other primary literatureHumanActiveForensic toxicology2025
Tsujikawa K, Okada Y, Segawa H, et al.
Pediatric Exposures Associated with Caffeine Energy Products Reported to United States Poison Centers, 2011-2023.Other primary literatureHumanActiveJournal of medical toxicology : official journal of the American College of Medical Toxicology2025
Thompson TR, Hays HL, Kistamgari S, et al.
An Exploration of the Interplay Between Caffeine and Antidepressants Through the Lens of Pharmacokinetics and Pharmacodynamics.ReviewHuman & animalActiveEuropean journal of drug metabolism and pharmacokinetics2025
Truong J, Abu-Suriya N, Tory D, et al.
Longitudinal Effects of Lifetime Caffeine Consumption on Levels of Depression, Anxiety, and Stress: A Comprehensive Review.ReviewHumanActiveCurrent nutrition reports2025
Unsal S, Sanlier N
Caffeine and Sports Performance: The Conflict between Caffeine Intake to Enhance Performance and Avoiding Caffeine to Ensure Sleep Quality.ReviewHumanActiveSports medicine (Auckland, N.Z.)2025
Silva H, Del Coso J, Pickering C
What is the Role of Caffeine in the Management of Preterm Infants?ReviewUnknownActiveCurrent treatment options in pediatrics2025
Rub DM, Eichenwald EC
Changes in the swimming behavior of Temora turbinata (Copepoda, Calanoida) in response to sub-lethal concentrations of caffeine and triclosan.Other primary literatureAnimalActiveAquatic toxicology (Amsterdam, Netherlands)2025
Moreno-Vega G, Frazão LR, De-La-Cruz LT, et al.
Caffeine improves diethylnitrosamine-induced hepatocellular carcinoma by inhibiting cAMP/PKA/CREB signaling in rats.Other primary literatureUnknownActiveBiochemistry and biophysics reports2025
Shan L, Wang C, Fang X, et al.
Sublethal effects of L-tryptophan and caffeine on planarian physiology: Insights into serotonergic and purinergic disruption in freshwater ecosystems.Other primary literatureAnimalActiveChemico-biological interactions2025
Martins Castro E, Luciano Braguini W
Low-Dose Caffeine Supplementation Is a Valuable Strategy for Increasing Time to Exhaustion, Explosive Power, and Reducing Muscle Soreness in Professional Male Kickboxers.Other primary literatureUnknownActiveCurrent developments in nutrition2025
Saremi M, Shahriari F, Hemmatinafar M, et al.
Combined Effects of Postactivation Performance Enhancement and Caffeine Intake on Explosive and Anaerobic Power in Recreationally Active Males.Other primary literatureUnknownActiveCurrent developments in nutrition2025
Heydari N, Shojaee M, Nemati J, et al.
Caffeine, riboflavin and curcumin amended clays for PFAS binding.Other primary literatureUnknownActiveComputers & chemical engineering2025
Xenophontos X, Oladele JO, Wang M, et al.
The association between per- and polyfluoroalkyl substances and biological aging among middle and older age adults: The moderating effect of caffeine.Other primary literatureHumanActiveEcotoxicology and environmental safety2025
Yan S, Liu Y, Wang H, et al.
Controlled release of caffeine from oat globulin nanocomplexes: Biocompatibility and gastrointestinal dynamics.Other primary literatureHuman & animalActiveFood chemistry2025
Lin J, Liu H, Yang J, et al.
Caffeine supplement, inflammation, and hepatic function in cirrhotic patients: A randomized, placebo- controlled, clinical trial.Other primary literatureUnknownActiveHeliyon2025
Abbas-Hashemi SA, Yari Z, Hatami B, et al.
A comparison of theacrine and methylliberine with caffeine as salivary markers for determining gastric emptying.Other primary literatureUnknownActiveInternational journal of pharmaceutics: X2025
Wildgrube T, Senekowitsch S, Krüger R, et al.
Nighttime caffeine intake increases motor impulsivity.Other primary literatureUnknownActiveiScience2025
Saldes EB, Sabandal PR, Han KA
Caffeine, Daytime Sleepiness, and Conduct Problems Among Early Adolescents: A Longitudinal Analysis.Other primary literatureHumanActiveThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2025
Kogan SM, Lilly CL, James JE, et al.
Caffeine intake associated with a lower risk of liver fibrosis in different glucose status.Other primary literatureHumanActiveJournal of advanced research2025
Han J, Liu C, Yang H, et al.
Caffeine Overdose Resulting in Seizure-like Activity and Rhabdomyolysis in a Child: A Case Report.Other primary literatureHumanActiveThe Journal of emergency medicine2025
Stephanos K, Hayes BD
Management of caffeine in wastewater using nanolayered material: An integrated study of process kinetics, modeling, and toxicity assessment.Other primary literatureHumanActiveJournal of environmental management2025
Shehata N, Abo El-Ela FI, Singh S, et al.
Effects of emerging pollutant mixtures: Assessing the impact of caffeine and ionic liquid on cyanobacteria and diatom species.Other primary literatureUnknownActiveJournal of hazardous materials2025
Sharma L, Kudłak B, Stoń-Egiert J, et al.
Too much or too little caffeine? Determination of content in thermogenic capsules by quantitative <sup>1</sup>H nuclear magnetic resonance (qNMR).Other primary literatureUnknownActiveJournal of pharmaceutical and biomedical analysis2025
Longhi GS, Crocoli LC, Armando YP, et al.
Suicidal intoxication by the ingestion of over-the-counter caffeine pills.Other primary literatureHumanActiveLegal medicine (Tokyo, Japan)2025
Yamamoto H, Ishida Y, Ishigami A, et al.
Pharmaceutical residues and caffeine in Arctic fjord waters (west Spitsbergen).Other primary literatureUnknownActiveMarine pollution bulletin2025
Pouch A, Pazdro K
Multi-ingredient energy dietary supplement with a small amount of caffeine modulates central and autonomic nervous system after a single use.Randomized controlled trialHumanActiveNeuroscience2025
Maciejewska K, Duch K, Giza M, et al.
Efficacy and safety of intravenously applied caffeine augmentation in electroconvulsive therapy.Other primary literatureUnknownActiveNeuroscience applied2025
Ridder MD, Ulrich S, Vettermann R, et al.
Associations between prenatal caffeine exposure and child development: Longitudinal results from the Adolescent Brain Cognitive Development (ABCD) Study.Other primary literatureHumanActiveNeurotoxicology and teratology2025
Modi H, Baranger DAA, Paul SE, et al.
Obesity as an influencing factor for the occurrence of caffeine-induced effects in women.Randomized controlled trialHumanActiveNutrition, metabolism, and cardiovascular diseases : NMCD2025
Domaszewski P, Konieczny M, Pakosz P, et al.
US parent perspectives on teen caffeine intake: An opportunity for health care provider guidance.Other primary literatureUnknownActivePreventive medicine reports2025
Clark SJ, Gebremariam A, Schultz S, et al.
Caffeine ameliorates metabolic-associated steatohepatitis by rescuing hepatic Dusp9.Other primary literatureHuman & animalActiveRedox biology2025
Xin X, Chen C, Xu X, et al.
Massive caffeine overdose with extremely high blood caffeine concentration and prolonged toxidrome.Other primary literatureUnknownActiveToxicology reports2025
Okazaki Y, Hitomi S, Taguchi S, et al.
Can oral caffeine decrease postoperative opioid consumption following posterior spinal fusion in adolescent idiopathic scoliosis? A randomized placebo-controlled trial.Other primary literatureUnknownActiveNorth American Spine Society journal2025
Stuedemann A, Schwend RM, Shaw KA, et al.
High-dose L-theanine-caffeine combination improves neurobehavioural and neurophysiological measures of selective attention in acutely sleep-deprived young adults: a double-blind, placebo-controlled crossover study.Randomized controlled trialHumanActiveThe British journal of nutrition2025
Nawarathna GS, Ariyasinghe DI, Dassanayake TL
Greener and Whiter Analytical Procedure for Theobromine and Caffeine Determination in Tea Using Dimethyl Carbonate as an Extraction Solvent and Mobile Phase Constituent in Reversed-Phase Liquid Chromatography.Other primary literatureUnknownActiveACS omega2025
Kalisz O, Catani M, Bocian S
Crystal Structure of Melphalan Hydrochloride and Its Association with Caffeine Improves Its Antineoplastic Action.Other primary literatureUnknownActiveACS omega2025
da Silva JP, Cristina da Silva Batista C, Schumacher ML, et al.
A Niobium Coordination Polymer as an Efficient Sorbent for Caffeine Detection in Surface Water.Other primary literatureUnknownActiveACS omega2025
Squizatto EP, Ribeiro IS, Pereira MVS, et al.
Exploring Caffeine Extraction Using Hydrophobic Deep Eutectic Solvents: Experimental and Theoretical Approaches.Other primary literatureUnknownActiveACS omega2025
Pishro KA, Silva LS, Lamarca RS, et al.
Interfacial Characterization of the Electrochemical Adsorption of Caffeine on Poly(pyrrole) Nanotubes/Silica.Other primary literatureUnknownActiveACS omega2025
Valerio TL, Boaron CK, Marchesi LF, et al.
Reducing the risk of sudden unexpected infant death: the caffeine hypothesis.ReviewHumanActiveJournal of perinatology : official journal of the California Perinatal Association2025
Hegyi T, Ostfeld BM
Associations of caffeine and caffeine metabolites with sex hormones among 6-19-year-old children and adolescents.Other primary literatureHumanActiveScientific reports2025
Li S, Yuan Z, Zhao Y, et al.
Caffeine-augmented exercise as a pretreatment for locomotor and balance impairments induced by REM sleep deprivation in rats.Other primary literatureAnimalActiveScientific reports2025
Karami E, Sarkaki A, Farbood Y, et al.
A randomized controlled trial on the effectiveness of low-level laser therapy versus paracetamol-caffeine for pain control during overall orthodontic treatment.Randomized controlled trialHumanActiveScientific reports2025
Owayda AM, Hajeer MY, Al-Sabbagh R, et al.
Iron oxide nanoparticles from clove and green coffee for antioxidant and antimicrobial activities and analytical application in caffeine removal.Other primary literatureHumanActiveScientific reports2025
Atta RR, Eweis AA, Mohammed DA, et al.
Elucidation of the effects of caffeine consumption on estrous cycle, hematology, and lipid profile of female Wistar rats.Other primary literatureAnimalActiveScientific reports2025
Ogunwole E, Ogunmiluyi OE, Adesida AO, et al.
The effect of alpha lipoic acid and caffeine loaded into chitosan nanoparticles on the hypothalamic amino acid neurotransmitters in a rat model of obesity.Other primary literatureAnimalActiveScientific reports2025
Khadrawy YA, Khoder NM, El-Gizawy MM, et al.
Therapeutic effects and potential mechanisms of caffeine on obese polycystic ovary syndrome: bioinformatic analysis and experimental validation.Other primary literatureHuman & animalActiveScientific reports2025
Bai T, Hu Y, Zhou J, et al.
An electrochemical bio-electronic tongue based on borophene/PPy@ITO hybrid for selective caffeine identification.Other primary literatureHumanActiveThe Analyst2025
Ahmed S, Ansari A, De B, et al.
The relationship between work addiction and addictions to social media, shopping, food, caffeine, and nicotine.Other primary literatureUnknownActiveAustralian journal of psychology2025
Özsoy E, Griffiths MD, Tınmaz Karaçay G, et al.
The role of caffeine and probiotics in modulating biochemical alterations induced by constant light-mediated circadian rhythm disruption in a rat model.Other primary literatureAnimalActiveChronobiology international2025
Shamandy AM, Abdel-Rahman M, El-Hennamy RE, et al.
Association between caffeine intake and fat free mass index: a retrospective cohort study.Other primary literatureHumanActiveJournal of the International Society of Sports Nutrition2025
Tian YL, Liu X, Yang MY, et al.
Predictors of caffeine consumption patterns in high school athletes.Other primary literatureHumanActiveJournal of the International Society of Sports Nutrition2025
O'Connell EM, Hatfield DL, Stors A, et al.
Low-dose caffeine enhances cognitive processing but not physical performance in fatigued taekwondo athletes: a randomized crossover trial.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2025
Nana A, Ramyarangsi P, Jamwai L, et al.
No effects of caffeine on cycling to exhaustion and perceptual responses in non-caffeine-restricted subjects.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2025
Weippert M, Behrens M, Schlegel M, et al.
The effects of mental fatigue and caffeine on basketball performance: insights from a crossover study.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2025
Hemmat M, Nazemzadegan G, Niknam A, et al.
Transcranial direct current stimulation combined with caffeine promotes executive function in healthy females.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2025
Yuan W, Nitsche MA, Yue T, et al.
Neuromuscular adaptations to caffeine supplementation in low-load resistance training with blood flow restriction.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2025
Lin YT, Wu CL, Wu CC, et al.
Performance-enhancing effects of caffeine and L-Theanine among Iranian elite wrestlers: a focus on cognitive and specific physical performance.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2025
Razazan R, Hemmatinafar M, Imanian B, et al.
Caffeine and taurine: a systematic review and network meta-analysis of their individual and combined effects on physical capacity, cognitive function, and physiological markers.Systematic reviewHumanActiveJournal of the International Society of Sports Nutrition2025
Deng H, Wang L, Liu P, et al.
Caffeine consumption patterns, motivations, and adverse effects among Brazilian esports players: a cross-sectional study.Other primary literatureHumanActiveJournal of the International Society of Sports Nutrition2025
Abhulime EWM, André HCS, André HCS, et al.
Caffeine removal in wastewater: a comprehensive review of current treatment plants and small-scale innovations.Other primary literatureUnknownActiveEnvironmental technology reviews2025
Yang Y, Wan Y, Chen H, et al.
Respiratory Responses to a Single Oral Dose of Caffeine in Male Sprague-Dawley Rats.Other primary literatureAnimalActiveJournal of medicinal food2025
Cho SH, Kim M, Doo M, et al.
When coronary spasm strikes: a case report on the dreadful association between cannabinoids and caffeine.Other primary literatureUnknownActiveEuropean heart journal. Case reports2025
Colombo G, Selimi A, Cesari A, et al.
Effects of Tea (Camellia sinensis) or its Bioactive Compounds l-Theanine or l-Theanine plus Caffeine on Cognition, Sleep, and Mood in Healthy Participants: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Meta-analysisHumanActiveNutrition reviews2025
Payne ER, Aceves-Martins M, Dubost J, et al.
Dose and timing effects of caffeine on subsequent sleep: a randomized clinical crossover trial.Randomized controlled trialHumanActiveSleep2025
Gardiner CL, Weakley J, Burke LM, et al.
Preliminary findings on caffeine intake, screen time, social factors, and psychological well-being: their impact on chronotype and sleep health in Hispanic adolescents.Other primary literatureUnknownActiveSleep advances : a journal of the Sleep Research Society2025
Wallace AL, Aguinaldo L, Thomas ML, et al.
Abnormal chenodexycholic acid metabolism programming promotes cartilage matrix degradation in male adult offspring rats induced by prenatal caffeine exposure.Other primary literatureUnknownActiveToxicology research2025
Li B, Gao H, Xiao H, et al.
Coriobacteriia may affect the occurrence of hepatocellular carcinoma through the pyrimidine, caffeine, urea cycle and glutamate metabolic pathways.Other primary literatureHumanActiveMedicine2025
Dai J, Li Q, Chen J, et al.
Total caffeine intake is associated with lower serum α-Klotho and may impact its detection accuracy: Evidence from NHANES 2007 to 2016 and molecular docking.Other primary literatureHumanActiveMedicine2025
Shi FE, Yu Z, Huang Z, et al.
Cardiovascular and locomotor effects of binary mixtures of common 'bath salts' constituents: Studies with methylone, methylenedioxypyrovalerone and caffeine in rats.Other primary literatureAnimalActiveBritish journal of pharmacology2025
Seaman RW Jr, Galindo DG, Stinson BT, et al.
The effects of caffeine and adenosine on the microbiome and lipidome of the scalp.Randomized controlled trialHumanActiveInternational journal of cosmetic science2025
Li F, Liu S, Han Z, et al.
A Novel Approach Against Male Pattern Hair Loss With Topical Dimethylglycine Sodium Salt (DMG-Na) and Caffeine: Efficacy of a 24-Week, Double-Blind, Randomized, Placebo-Controlled Trial.Randomized controlled trialHumanActiveJournal of cosmetic dermatology2025
Celleno L, Bussoletti C, Tolaini MV, et al.
Short-Term Dietary Caffeine Intake for Alleviating Symptoms of Burning Mouth Syndrome: A Randomised Controlled Comparison With Alpha-Lipoic Acid.Randomized controlled trialHumanActiveJournal of oral rehabilitation2025
Wu C, Yuan P, Qiu X, et al.
Can Intravenous Caffeine Citrate Be Used for Severe Asthma Exacerbation in Children? A Retrospective Comparative Study.Other primary literatureHumanActiveJournal of paediatrics and child health2025
Brooks R, Babushkin V, Rekhtman D, et al.
Maternal caffeine intake during pregnancy and the risk of childhood asthma by 10 years of age-Evidence from The Generation XXI birth cohort study.Other primary literatureHumanActivePediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2025
de Castro Mendes F, Severo M, Paciência I, et al.
JA Regulates Caffeine Biosynthesis in Tea Leaf for Resistance Against Fungal Infection and Antagonises With GA to Balance the Defence-Growth Trade-Off via CsDELLA-JAZ-MYC2-MYB184-TCS1 Module.Other primary literatureUnknownActivePlant biotechnology journal2025
Ye Z, Zheng Z, Wang J, et al.
Impact of acute caffeine intake on local tolerance to cold before and after total sleep deprivation.Randomized controlled trialHumanActiveExperimental physiology2025
de Lorgeril B, Tardo-Dino PE, Bourrilhon C, et al.
Prophylactic caffeine mitigates systemic hypercapnia and headache during graded carbon dioxide exposure in healthy males and females: a randomized crossover trial.Randomized controlled trialHumanActiveJournal of applied physiology (Bethesda, Md. : 1985)2025
Ryan BJ, Mayer TA, Alba BK, et al.
Potential Synergistic Effects of Caffeine and Naringin on Mitochondrial Biogenesis and Hepatic Steatosis in Adult Male Rats With NAFLD Induced by a High-Fat Diet.Other primary literatureAnimalActiveBioMed research international2025
Azizollahi M, Nasehi Z, Derakhshan M, et al.
Caffeine Treatment for Prostaglandin E1-Induced Apnea Prevention in Congenital Heart Disease Neonates: A Randomized Clinical Trial.Other primary literatureUnknownActiveCritical care research and practice2025
Salamati L, Dehghan B, Sabri MR, et al.
Caffeine Acts as an Agonist of Siglec-6, Inhibits MRGPRX2-Triggered Mast Cell Degranulation and Anaphylactoid Reactions.Other primary literatureAnimalActiveMediators of inflammation2025
Ding Y, Wang N, Zhao C, et al.
Caffeine, MitoQ, and GABA Prophylaxis of Mitochondrial Dysfunction Induced in Human Pulmonary Cells by Normobaric-Hyperoxia and Hyperbaric-Hyperoxia.Other primary literatureHumanActiveOxidative medicine and cellular longevity2025
Hossain T, Secor JT, Eckmann DM
Paracetamol and Caffeine Combination in Pain Management: A Narrative Review.ReviewHuman & animalActivePain research & management2025
Lanteri-Minet M, Pegahi R
Caffeine Consumption, Psychological Distress, and Insomnia in a Cohort of Individuals with Depression.Other primary literatureUnknownActiveComplex psychiatry2025
McIntosh HA, Borgas AJ, Aouira N, et al.
Habitual Caffeine Consumption and Training Status Affect the Ergogenicity of Acute Caffeine Intake on Exercise Performance.Randomized controlled trialHumanActiveSports health2025
Khodadadi D, Azimi F, Eghbal Moghanlou A, et al.
Comparison between paracetamol, paracetamol-codeine and paracetamol-caffeine in the treatment of acute post-traumatic pain: A randomized controlled trial.Other primary literatureUnknownActiveBritish journal of pain2025
Achek S, Toumia M, Dhaoui R, et al.
Impact of caffeine consumption on headache severity, sleep quality, and psychiatric symptoms in patients with idiopathic intracranial hypertension: a cross-sectional study.Other primary literatureHumanActiveThe journal of headache and pain2025
Abdelghaffar M, Hussein M, Magdy R, et al.
Short- and long-term neurobehavioural impairments in mice offspring following chronic perinatal caffeine exposure and withdrawal.Other primary literatureAnimalActiveBMC neuroscience2025
Olopade FE, Folarin OR, Gilbert TT, et al.
Network analysis of caffeine use disorder, withdrawal symptoms, and psychiatric symptoms.Other primary literatureHumanActiveBMC psychiatry2025
Davoudi M, Abdoli F, Momeni F, et al.
Caffeine mitigates ROS accumulation and attenuates motor neuron degeneration in the wobbler mouse model of amyotrophic lateral sclerosis.Other primary literatureHuman & animalActiveCell communication and signaling : CCS2025
Epplen ASC, Rothöft M, Stahlke S, et al.
Caffeine to improve neurodevelopmental outcomes in infants born late preterm (The Latte Trial): study protocol for a randomised controlled trial.Other primary literatureHumanActiveTrials2025
Canning JM, McKinlay CJD, McNamara DG, et al.
Thermo-acoustic investigation on mixtures of Tetramethyl ammonium hydroxide and caffeine in aqueous medium with the goal to understand their mutual interactions.Other primary literatureUnknownActiveBMC chemistry2025
Baral AK, Talukdar M, Singh S
A new chromatographic approach for the simultaneous determination of tramadol, ibuprofen, and caffeine in a novel fixed-dose combination tablet: an integrated framework to analytical sustainability and multimodal analgesia.Other primary literatureUnknownActiveBMC chemistry2025
Wahba IA, Hassan SA, Fayed AS, et al.
Effect of caffeine on attack decision-making in trained beach volleyball players following prolonged cognitive effort induced by social media use: a randomized, single-blind, crossover pilot study.Other primary literatureUnknownActiveBMC sports science, medicine & rehabilitation2025
Costa YP, Lopes-da-Silva BS, Fonseca FS, et al.
The effect of low dose caffeine powder supplementation on serve speed, spike speed, and speed-endurance in elite sitting volleyball players: a randomized double-blind crossover study.Other primary literatureUnknownActiveBMC sports science, medicine & rehabilitation2025
Diedhiou AB, Erkan D, Guler M, et al.
Effects of caffeine supplementation on lipid profile and handgrip strength in cirrhotic patients: a randomized, placebo- controlled, clinical trial.Other primary literatureUnknownActiveBMC nutrition2025
Abbas-Hashemi SA, Yari Z, Hatami B, et al.
Factors associated with caffeine intake among undergraduates: a cross-sectional study from Palestine.Other primary literatureHumanActiveJournal of health, population, and nutrition2025
Hamdan M, Zidan S, Al-Amouri F, et al.
Clinical efficacy of different maintenance doses of caffeine citrate in the treatment of apnea of prematurity.Other primary literatureUnknownActivePakistan journal of medical sciences2025
Ji P, Wan Y, Yin J, et al.
Caffeine consumption as a potential risk factor of osteoporosis development among night shift workers: epidemiological evidences and hypothesis.ReviewHumanActiveInternational journal of occupational medicine and environmental health2025
Bukowska-Damska A, Jurewicz J, Jabłońska E
The effect of an additional pre-extubational loading dose of caffeine citrate on mechanically ventilated preterm infants (NEOKOFF trial): Study protocol for a multicenter randomized clinical trial.Other primary literatureHumanActivePloS one2025
Kovács K, Nagy R, Andréka L, et al.
Evaluation of caffeine modulation of topiramate effect on locomotor activity of zebrafish larvae in pentylenetetrazol-induced seizure model.Other primary literatureAnimalActivePloS one2025
Bartoszek A, Fornal E
Caffeine intake and awareness of its adverse effects: Insights from the medical students at the University of Tabuk.Other primary literatureHumanActivePloS one2025
El Seifi OS, Younis FE, Alsaiari NA, et al.
The effect of caffeine use in the relationship between gaming and sleep in adolescents: A mediation analysis.Other primary literatureHumanActiveJournal of behavioral addictions2025
Park JJ, Han X, Potenza MN, et al.
Caffeine toxicity in zebrafish - Neurobehavioral changes, developmental defects, and oxidative stress: A review.ReviewUnknownActiveBiomolecules & biomedicine2025
Ionescu C, Lungu PF, Rarinca V, et al.
Neuroprotective effects of caffeine, erythropoietin, magnesium sulfate, and thyroxine in preterm infants: a network meta-analysis.Other primary literatureUnknownActiveTranslational pediatrics2025
Wang Y, Wang S, Dou H, et al.
Association Between Caffeine Intake and Bowel Habits and Inflammatory Bowel Disease: A Population-Based Study.Other primary literatureUnknownActiveJournal of multidisciplinary healthcare2025
Yang X, Yan H, Chen Y, et al.
Cardiovascular Findings and Effects of Caffeine on Experimental Hypothyroidism.Other primary literatureAnimalActiveEndocrine, metabolic & immune disorders drug targets2025
Yuksel D, Ozmen O
Caffeine Modulates Cell Death and Telomerase Activity in Triple-negative Breast Cancer Cells.Other primary literatureUnknownActiveInternational journal of molecular and cellular medicine2025
Amira QH, Irdianto SA, Fadilah F, et al.
Caffeine and cardiovascular aging: exploring sex-specific impacts on risk and arrhythmias.Other primary literatureUnknownActiveJournal of geriatric cardiology : JGC2025
Farinetti A, Manenti A, Cocchi C, et al.
Caffeine Intoxication: An Analysis of Published Case Reports, 1883–2023.ReviewHumanActiveDeutsches Arzteblatt international2025
Uehlein S, Dechant K, Stahl K, et al.
Unveiling the influence of caffeine on topiramate: metabolomic marker analysis using liquid chromatography-mass spectrometry.Other primary literatureUnknownActiveFrontiers in molecular biosciences2025
Bartoszek A, Paszkowska E, Kozub-Pędrak A, et al.
The S-shaped association between dietary caffeine intake and severe headache or migraine: a cross-sectional study based on NHANES.Other primary literatureUnknownActiveFrontiers in neurology2025
Liao Z, Lin A, Zeng J, et al.
Caffeine consumption and exposure in Saudi Arabia: a cross-sectional analysis.Other primary literatureUnknownActiveFrontiers in nutrition2025
Fallata G, Alhumaidan O, Alkhunein S, et al.
The mediating role of caffeine and biological age in the association between dietary index for gut microbiota and osteoporosis.Other primary literatureUnknownActiveFrontiers in nutrition2025
Li Y, Cao H, Zhang J
Use of caffeine in 19,660 randomly selected U.S. adults: the role of overweight and obesity.Other primary literatureUnknownActiveFrontiers in nutrition2025
Tucker LA, Beltran F
Effects of progressive <i>versus</i> consistent dose of caffeine ingestion on volleyball players' exercise performance adaptations following plyometric jump training.Other primary literatureUnknownActiveFrontiers in nutrition2025
Zhu G, Fu K, Xie Y
Varying doses of evening caffeine ingestion have different effects on rowing ergometer performance, sleep quality, and wakefulness scores.Other primary literatureUnknownActiveFrontiers in nutrition2025
Karakulak I, Yildirim UC, Erkan D, et al.
Effects of acute caffeine intake on muscular power during resistance exercise: a systematic review and meta-analysis.Systematic reviewUnknownActiveFrontiers in nutrition2025
Xiao Y, Ding L, Xu Z, et al.
Effect of caffeine ingestion on cycling performance: a systematic review and meta-analysis.Systematic reviewUnknownActiveFrontiers in nutrition2025
Wu J, Xu K, Yin M, et al.
Impact of cessation of caffeine citrate therapy on intermittent hypoxemia patterns among preterm infants born before 34 weeks.Other primary literatureUnknownActiveFrontiers in pediatrics2025
Mashep PK, Ochieng R, Coleman J, et al.
Caffeine use in preterm neonates: national insights into Turkish NICU practices.Other primary literatureUnknownActiveFrontiers in pediatrics2025
Unal S, Beken S, Anuk Ince D, et al.
Early caffeine therapy decreases bronchopulmonary dysplasia but might increase mortality in preterm infants? a systematic review and meta-analysis.Systematic reviewUnknownActiveFrontiers in pediatrics2025
Ma J, Chen L, Mu K, et al.
Effect of caffeine supplementation on anaerobic and aerobic performance in sleep-restricted male college soccer players.Other primary literatureUnknownActiveFrontiers in physiology2025
Cheng R, Wang N, He W, et al.
Gaming disorder and problematic caffeine consumption in adolescents: a narrative review and public health framework.ReviewUnknownActiveFrontiers in psychology2025
Park JJ, Zhao Y, Potenza MN
Caffeine Protects Against Hyperoxia-Induced Structural Lung Injury and Restores Alveolar Development in Neonatal Rats.Other primary literatureUnknownActiveAntioxidants (Basel, Switzerland)2025
Endesfelder S, Bührer C
Varietal Differences in the Environmental Behavior of 14C-Caffeine in Tea Plants: Accumulation, Subcellular Distribution, and Metabolism.Other primary literatureUnknownActiveBiology2025
Chen Y, Song K, Hu H, et al.
Caffeine May Delay the Radiation-Induced Nucleoshuttling of the ATM Kinase and Reduce the Recognition of the DNA Double-Strand Breaks in Human Cells.Other primary literatureHumanActiveBiomolecules2025
Moliard L, Restier-Verlet J, Al-Choboq J, et al.
The Fetal Effect of Maternal Caffeine Consumption During Pregnancy-A Review.ReviewUnknownActiveBiomedicines2025
Dube R, Kar SS, Bahutair SNM, et al.
Development of an Electrochemical Sensor Based on Molecularly Imprinted Polymer Using Functionalized Gold Nanoparticles for Caffeine Quantification.Other primary literatureUnknownActiveBiosensors2025
Espinoza-Torres S, Choquehuanca-Azaña A, Rufino M, et al.
Psychophysiological Effects of a Single Dose vs. Partial Dose of Caffeine Gum Supplementation on the Cognitive Performance of Healthy University Students: A Placebo Controlled Study.Other primary literatureUnknownActiveBrain sciences2025
Saavedra Velasquez N, Francino Barrera G, Cuadrado Peñafiel V, et al.
Effects of Caffeine on THP-1 Myelogenous Cell Inflammatory Gene Expression.Other primary literatureUnknownActiveCurrent issues in molecular biology2025
Htun ZT, Raffay TM, Martin RJ, et al.
Numerical Investigation of Conventional and Ultrasound-Assisted Aqueous Extraction of Caffeine from Whole Green Robusta Coffee Beans: Extraction Enhancement via Changing of Extraction Water.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2025
Bawornruttanaboonya K, Chindapan N, Devahastin S
Formulation of Caffeine-Hydroxypropyl-β-Cyclodextrin Complex in Hydrogel for Skin Treatment.Other primary literatureUnknownActiveGels (Basel, Switzerland)2025
Radeva L, Kalampalika E, Yordanov Y, et al.
Caffeine as an Active Ingredient in Cosmetic Preparations Against Hair Loss: A Systematic Review of Available Clinical Evidence.ReviewUnknownActiveHealthcare (Basel, Switzerland)2025
Szendzielorz E, Spiewak R
Caffeine in Aging Brains: Cognitive Enhancement, Neurodegeneration, and Emerging Concerns About Addiction.ReviewHumanActiveInternational journal of environmental research and public health2025
Carbone MG, Pagni G, Tagliarini C, et al.
Modulation of the Antitumor Response to Metformin, Caffeine, and Sodium Dichloroacetate by the Hypoxic Microenvironment in Lung Cancer Cells.Other primary literatureHumanActiveInternational journal of molecular sciences2025
Garcia-Martin MO, Castillejos-Lopez M, Prado-Garcia H, et al.
Caffeine as a Modulator in Oncology: Mechanisms of Action and Potential for Adjuvant Therapy.ReviewHuman & animalActiveInternational journal of molecular sciences2025
Rembiałkowska N, Demiy A, Dąbrowska A, et al.
Methylxanthines: The Major Impact of Caffeine in Clinical Practice in Patients Diagnosed with Apnea of Prematurity.ReviewUnknownActiveJournal of clinical medicine2025
Neamțu AV, Zlatian OM, Manda CV, et al.
Effects of Caffeine on Dental Mesenchymal Stem Cells: Implications for Regenerative Applications.Other primary literatureUnknownActiveJournal of functional biomaterials2025
Lugo-Sanchez AA, Chavez-Granados PA, Jurado CA, et al.
The Role of Xenobiotic Caffeine on Cardiovascular Health: Promises and Challenges.ReviewUnknownActiveJournal of xenobiotics2025
Campagna R, Vignini A
Impact of Caffeine on Aquatic Ecosystems: Assessing Trophic-Level Biological Responses.Other primary literatureUnknownActiveJournal of xenobiotics2025
Rodrigues S, Alves RS, Antunes SC
Effects of Different Doses of Caffeine on Endurance Exercise Performance in the Heat.Other primary literatureUnknownActiveLife (Basel, Switzerland)2025
Wu W, Tao X, Dong H, et al.
Modulatory Effects of Caffeine on Imatinib Binding: A Molecular Docking Study Targeting CYP3A4.Other primary literatureUnknownActiveLife (Basel, Switzerland)2025
Amzoiu MO, Popescu GS, Amzoiu E, et al.
Differential Time-of-Day Effects of Caffeine Capsule and Mouth Rinse on Cognitive Performance in Adolescent Male Volleyball Athletes: A Randomized Crossover Investigation.Other primary literatureUnknownActiveLife (Basel, Switzerland)2025
Amor SB, Dhahbi W, Bougrine H, et al.
Interaction Between CYP1A2-Related Caffeine Metabolism and Vitamin B12/Folate Status in Patients with Metabolic Syndrome: A Novel Biomarker Axis.Other primary literatureUnknownActiveMetabolites2025
Popa LC, Abu-Awwad A, Farcas SS, et al.
Caffeine as an Active Molecule in Cosmetic Products for Hair Loss: Its Mechanisms of Action in the Context of Hair Physiology and Pathology.ReviewHuman & animalActiveMolecules (Basel, Switzerland)2025
Szendzielorz E, Spiewak R
Experimental and Theoretical Study of the Synthesis of a Deep Eutectic Solvent Based on Protonated Caffeine, Ethylene Glycol, and ZnCl<sub>2</sub>.Other primary literatureUnknownActiveMolecules (Basel, Switzerland)2025
Benavides-Maya LS, Torres-Perdomo MF, Ocampo-Carmona LM, et al.
Determination of Caffeine in Energy Drinks Using a Composite Modified Sensor Based on Magnetic Nanoparticles.Other primary literatureUnknownActiveMolecules (Basel, Switzerland)2025
Tyszczuk-Rotko K, Liwak A, Keller A
Hybrid Uracil Derivatives with Caffeine and Gramine Obtained via Click Chemistry as Potential Antioxidants and Inhibitors of Plant Pathogens.Other primary literatureUnknownActiveMolecules (Basel, Switzerland)2025
Szlaużys M, Ostrowski K, Nowak D, et al.
Development of a Validated High-Performance Thin-Layer Chromatography (HPTLC) Analysis Protocol for Salivary Caffeine Used as a Probe Drug.Other primary literatureHumanActiveMolecules (Basel, Switzerland)2025
Sikdar KMYK, Shalan A, Castejon V, et al.
Effects of Caffeine Intake Combined with Self-Selected Music During Warm-Up on Anaerobic Performance: A Randomized, Double-Blind, Crossover Study.Randomized controlled trialHumanActiveNutrients2025
Qiu B, Wang Z, Zhang Y, et al.
Caffeine Combined with Excitatory Neuromodulation Based on Transcranial Direct Current Stimulation (tDCS) Enhances Performance in a Time-Trial CrossFit<sup>®</sup> Workout: A Randomized, Placebo-Controlled, Double-Blind Study.Randomized controlled trialHumanActiveNutrients2025
Sá Filho AS, Albernaz-Silva T, Inacio PA, et al.
Effects of Caffeine Intake on Self-Administered Sleeping Quality and Wearable Monitoring of Sleep in a Cohort of Young Healthy Adults.Observational studyHumanActiveNutrients2025
Schlichtiger J, Brunner S, Strüven A, et al.
Urinary Caffeine Levels in Chinese Children: Insights from Diet, Gender, and Regional Variations.Other primary literatureHumanActiveNutrients2025
Deng WJ, Lee JC
Ergogenic Effects of Combined Caffeine Supplementation and Motivational Music on Anaerobic Performance in Female Handball Players: A Randomized Double-Blind Controlled Trial.Randomized controlled trialHumanActiveNutrients2025
Bougrine H, Paillard T, Jebabli N, et al.
Caffeine: A Neuroprotectant and Neurotoxin in Traumatic Brain Injury (TBI).ReviewHuman & animalActiveNutrients2025
Sharma B, Agriantonis G, Dawson-Moroz S, et al.
The Acute Effects of Caffeine Supplementation on Anaerobic Performance and Functional Strength in Female Soccer Players.Randomized controlled trialHumanActiveNutrients2025
Mor H, Mor A, Abdioğlu M, et al.
Genotype-Drug-Diet Interactions in Metabolic Regulation: CYP1A2 rs762551 Modulates the Effect of Caffeine on Lipid and Glucose Profiles in the Context of Pharmacotherapy.Other primary literatureHumanActiveNutrients2025
Popa LC, Abu-Awwad A, Farcas SS, et al.
Association Between the Consumption of Sugar-Sweetened Beverages and High-Caffeine Drinks and Self-Reported Mental Health Conditions Among Korean Adolescents.Other primary literatureHumanActiveNutrients2025
Lee SJ, Na Y, Lee KW
Caffeine Intake Mediates the Relationship Between Problematic Overstudying and Psychological Distress.Other primary literatureHumanActiveNutrients2025
Kosecka O, Charzyńska E, Czerwiński SK, et al.
Caffeinated Energy Drink Formulations Differentially Impact Hydration Versus Water: Does Habitual Caffeine Intake or Biological Sex Matter?Other primary literatureHumanActiveNutrients2025
Millard-Stafford M, Hack B, Harp A, et al.
Pregnancy and Caffeine Metabolism: Updated Insights and Implications for Maternal-Fetal Health.ReviewHumanActiveNutrients2025
Struniewicz KM, Ptaszek MM, Ziółkowska AM, et al.
Disclosure of Genotype Information to Reduce Caffeine Intake in Slow Metabolizers: Findings from a Randomized Controlled Trial on Personalized Dietary Interventions.Randomized controlled trialHumanActiveNutrients2025
Bulczak E, Chmurzynska A
Effects of Acute Caffeine Ingestion on Repeated Sprint Ability: A Systematic Review and Meta-Analysis.Meta-analysisHumanActiveNutrients2025
Wang Y, Su W, Zhang S, et al.
Effects of Caffeine Dose and Administration Method on Time-Trial Performance: A Systematic Review and Network Meta-Analysis.Systematic reviewHumanActiveNutrients2025
Xue R, Huang J, Chen B, et al.
A Randomized Study to Examine the Ability of a Caffeine-Based Energy Drink to Impact Energy Expenditure, Fat Oxidation, and Cognitive Performance.Randomized controlled trialHumanActiveNutrients2025
Krieger J, Schrautemeier A, Hagele A, et al.
Multi-Omics and Molecular Docking Studies on Caffeine for Its Skin Rejuvenating Potentials.Other primary literatureUnknownActivePharmaceuticals (Basel, Switzerland)2025
Shu P, Zhao N, Zhou Q, et al.
Low Caffeine Concentrations Induce Callus and Direct Organogenesis in Tissue Cultures of <i>Ornithogalum dubium</i>.Other primary literatureUnknownActivePlants (Basel, Switzerland)2025
Petti C
The Application of an Ultra-Thin, High-Density μECoG Array in Dissecting Caffeine-Induced Cortical Dynamics in Mice.Other primary literatureAnimalActiveSensors (Basel, Switzerland)2025
Hu Y, Zhang B, Hu Z, et al.
Caffeine Effects on Physical Performance and Sport-Specific Skills in Elite Youth Soccer Players: A Randomised Trial Using the Balanced Placebo Design.Other primary literatureUnknownActiveSports (Basel, Switzerland)2025
Bezuglov E, Vakhidov T, Morgans R, et al.
Does Personality Modulate the Sensitivity to Contaminants? A Case Study with Cadmium and Caffeine.Other primary literatureUnknownActiveToxics2025
Santos N, Reis S, Domingues I, et al.
Effects of Caffeine Exposure on Behaviour, Development and Physiology of the Freshwater Snail Physella acuta (Draparnaud, 1805).Other primary literatureUnknownActiveToxics2025
Mohamed-Benhamu A
Study on Urinary Caffeine and Caffeine Metabolite Levels in American Adults with Coronary Heart Disease: A Cross-Sectional NHANES Study (2009-2014).Other primary literatureHumanActiveArquivos brasileiros de cardiologia2025
Li Q, Ke G, Liu M, et al.
Caffeine Supplementation and Hair: A Systematic Review.Systematic reviewHumanActiveJournal of drugs in dermatology : JDD2025
Ly N, Paiewonsky B, Fruechte S, et al.
Effects of <i>Eisenia bicyclis</i> Extract on Sleep Promotion in a Caffeine-Induced Insomnia Models.Other primary literatureAnimalActiveJournal of microbiology and biotechnology2025
Ha YJ, Lee S, Suh HJ, et al.
Excessive day time sleepiness, poor sleep quality, and their association to caffeine consumption among young Informational Technology professionals.Other primary literatureUnknownActiveIndustrial psychiatry journal2025
Raju A, Chandran M, Fredrick J
Caffeine Exerts Neither Ergogenic nor Hypoalgesic Effects on Sprint Interval Exercise with Intensive Exercise-Induced Muscle Pain.Randomized controlled trialHumanActiveJournal of sports science & medicine2025
Matsumura T, Sakai Y, Fukuzawa K, et al.
Mitigating Cadmium Toxicity: Role of Caffeine in the Reduction of Oxidative Stress.Other primary literatureAnimalActiveOpen veterinary journal2025
Aljazzar A
Caffeine-clarithromycin coadministration and hyperlactatemia in a young infant: a case report.Other primary literatureHumanActiveCritical care science2025
Volpon LC, Costa FM, Carlotti APCP
The Neuroprotective Effects of Caffeine in a Neonatal Hypoxia-Ischemia Model are Regulated through the AMPK/mTOR Pathway.Other primary literatureAnimalActiveInternational journal of biological sciences2025
Bernis ME, Burkard H, Bremer AS, et al.
Body fat percentage is a key factor in elevated plasma levels of caffeine and its metabolite in women.Other primary literatureHumanActivePeerJ2025
Domaszewski P, Konieczny M, Pakosz P, et al.
Association Between Caffeine Intake and Alzheimer's Disease Progression: A Systematic Review.ReviewUnknownActiveCureus2025
Ashfaq Z, Younas Z, Nathaniel E, et al.
Exploring the Link Between Caffeine Intake, Sleep Quality, and Restless Legs Syndrome Among Medical Students.Other primary literatureUnknownActiveCureus2025
Singla B, Abbas SF, Nadeem Khan M, et al.
Prolonged Respiratory Alkalosis Induced by Caffeine at Subtoxic Serum Concentrations.Other primary literatureUnknownActiveCureus2025
Inoue F, Okazaki Y, Ichiba T, et al.
Caffeine Consumption Patterns, Health Impacts, and Media Influence: A Narrative Review.ReviewUnknownActiveCureus2025
Rauf MQ, Sharma L, Essiet E, et al.
Neurocognitive and Neurological Effects of Coffee and Caffeine: A Narrative Review.ReviewUnknownActiveCureus2025
Pergolizzi JV Jr, Tenenbaum JT, Pergolizzi C, et al.
Controlled release of caffeine from oat globulin nanocomplexes: Biocompatibility and gastrointestinal dynamicsOther primary literatureUnknownUnknownFood Chemistry2025
Lin J, Liu H, Yang J, et al.
Management of caffeine in wastewater using nanolayered material: An integrated study of process kinetics, modeling, and toxicity assessmentOther primary literatureUnknownUnknownJournal of Environmental Management2025
Shehata N, Abo El-Ela FI, Singh S, et al.
Synergistic Neuroprotection by Caffeine and Astaxanthin Against CNS-OT.Other primary literatureAnimalActiveUndersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc2025
Rosenberg M, Ezra R, Arieli R, et al.
Strategies for cessation of caffeine administration in preterm infants.Meta-analysisHumanActiveThe Cochrane database of systematic reviews2024
Urru SA, Geist M, Carlinger R, et al.
Sperm miR-142-3p Reprogramming Mediates Paternal Pre-Pregnancy Caffeine Exposure-Induced Non-Alcoholic Steatohepatitis in Male Offspring Rats.Other primary literatureAnimalActiveAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024
Zhang C, Guo Y, Liu Y, et al.
Interaction of a caffeine overdose with clinical doses of contraceptive ethinyl estradiol in a young woman.Other primary literatureUnknownActiveAcute medicine & surgery2024
Adachi K, Murata M, Inada A, et al.
The risk of premature cardiac contractions (PAC/PVC) related to caffeine consumption among healthcare workers: A comprehensive review.Other primary literatureUnknownActiveHealth science reports2024
Abdolmaleki M, Ohadi L, Changizi F, et al.
Adolescent caffeine use and problematic school behavior: A longitudinal analysis of student survey data and teacher observations.Other primary literatureHumanActiveJournal of adolescence2024
Kristjansson AL, Lilly CL, Mann MJ, et al.
Expectancy for Adderall influences subjective mood and drug effects regardless of concurrent caffeine ingestion: A randomized controlled trial.Randomized controlled trialHumanActivePsychopharmacology2024
Looby A, Piccorelli AV, Zimmerman L, et al.
Chronic Caffeine Consumption, Alone or Combined with Agomelatine or Quetiapine, Reduces the Maximum EEG Peak, As Linked to Cortical Neurodegeneration, Ovarian Estrogen Receptor Alpha, and Melatonin Receptor 2.Other primary literatureAnimalActivePsychopharmacology2024
Abdelmissih S, Hosny SA, Elwi HM, et al.
Paraxanthine enhances memory and neuroplasticity more than caffeine in rats.Other primary literatureAnimalCorrectedExperimental brain research2024
Jäger R, Abou Sawan S, Orrú M, et al.
Caffeine gum improves 5 km running performance in recreational runners completing parkrun events.Randomized controlled trialHumanActiveEuropean journal of nutrition2024
Lynn A, Shaw C, Sorsby AC, et al.
Self-reported caffeine consumption miss-matched consumption measured by plasma levels of caffeine and its metabolites: results from two population-based studies.Other primary literatureHumanActiveEuropean journal of nutrition2024
Laaboub N, Ranjbar S, Strippoli MF, et al.
Exploring the relationship between caffeine metabolism-related CYP1A2 rs762551 polymorphism and team sport athlete status and training adaptations.Other primary literatureHumanActiveMolecular biology reports2024
Kazan HH, Bulgay C, Zorba E, et al.
Determination of caffeine in treated wastewater discharged in the Nile River with emphasis on the effect of zinc and physicochemical factors.Other primary literatureUnknownActiveEnvironmental science and pollution research international2024
Tawfik NAI, El-Bakary ZA, Abd El-Wakeil KF
Biological properties of caffeine, (+)-catechin, and theobromine: an in silico study.Other primary literatureUnknownActive3 Biotech2024
Dutra NS, da Silva D'Ávila CM, da Silva TC, et al.
The Role of the Combination Paracetamol/Caffeine in Treatment of Acute Migraine Pain: A Narrative Review.ReviewUnknownCorrectedPain and therapy2024
Barbanti P, Allais G, Cevoli S, et al.
Coffee and mental disorders: How caffeine affects anxiety and depression.ReviewHuman & animalActiveProgress in brain research2024
Meamar M, Raise-Abdullahi P, Rashidy-Pour A, et al.
JM-20 potently prevents the onset of caffeine-induced anxiogenic phenotypes in zebrafish (Danio rerio).Other primary literatureHuman & animalActiveComparative biochemistry and physiology. Toxicology & pharmacology : CBP2024
Dos Santos MM, Ferreira SA, de Macedo GT, et al.
Enhanced degradation of aqueous caffeine via cylindrical dielectric barrier discharge plasma: Efficacy and toxicity insights.Other primary literatureUnknownActiveChemosphere2024
Dahal R, Dhakal OB, Acharya TR, et al.
Effects of moderate caffeine intake in athletes.Other primary literatureHumanActiveEuropean journal of internal medicine2024
Mone P, Guerra G, Verderosa S, et al.
Coffee Intake, Plasma Caffeine Levels, and Kidney Function: Two-Sample Mendelian Randomization Among East Asian and European Ancestries.Other primary literatureUnknownActiveKidney international reports2024
Fujii R, Nakatochi M, Del Greco M F
Antagonistic interaction between caffeine and ketamine in zebrafish: Implications for aquatic toxicity.Other primary literatureUnknownActiveEnvironmental science and ecotechnology2024
Wang Z, Xu J, Du W
Engineering of zeolitic imidazolate frameworks based on magnetic three-dimensional graphene as effective and reusable adsorbent to enhance the adsorption and removal of caffeine from tea samples.Other primary literatureUnknownActiveFood chemistry2024
Hua Y, Liu G, Lin Z, et al.
Boosting physical performance in SD rats through brain-targeted delivery of caffeine-loaded transferrin liposomes.Other primary literatureUnknownActiveHeliyon2024
Yun H, Su W, You T, et al.
Acute exposure to caffeine improves foraging in an invasive ant.Other primary literatureUnknownActiveiScience2024
Galante H, De Agrò M, Koch A, et al.
Solar-driven persulfate degradation of caffeine and cephradine in synthetic human urine.Other primary literatureHumanActiveJournal of hazardous materials2024
Kung WM, Lin HH, Wang YH, et al.
Does ergogenic effect of caffeine supplementation depend on CYP1A2 genotypes? A systematic review with meta-analysis.Meta-analysisHumanActiveJournal of sport and health science2024
Wang J, Dewi L, Peng Y, et al.
Risperidone suppresses caffeine-induced hyperthermia and hyperactivity in rats.Other primary literatureAnimalActiveNeuroscience letters2024
Takano M, Okada T, Shioda K, et al.
Therapeutic effects of alpha lipoic acid and/or caffeine-loaded chitosan nanoparticles on memory impairment and neurochemical changes in high-fat diet-induced obese rats.Other primary literatureAnimalActivePhysiology & behavior2024
Hosny EN, Sawie HG, El-Gizawy MM, et al.
Caffeine intake during pregnancy and adverse outcomes: An integrative review.ReviewHumanActiveReproductive toxicology (Elmsford, N.Y.)2024
Rohweder R, de Oliveira Schmalfuss T, Dos Santos Borniger D, et al.
Prenatal caffeine consumption and neurobehavioral disorders - A systematic review.Systematic reviewHumanActiveReproductive toxicology (Elmsford, N.Y.)2024
Santana AB, Spelta LEW, Martinez-Sobalvarro JV, et al.
Exploring toxicological interactions in a changing sea: The case of the alkaloids caffeine and caulerpin.Other primary literatureHuman & animalActiveThe Science of the total environment2024
Russo T, Coppola F, Paris D, et al.
The influence of temperature on the impacts of caffeine in mussels: Evaluating subcellular impacts and model predictions.Other primary literatureAnimalActiveThe Science of the total environment2024
Cunha M, Petrillo V, Madeira M, et al.
Autophagy activated by GR/miR-421-3p/mTOR pathway as a compensatory mechanism participates in chondrodysplasia induced by prenatal caffeine exposure in male fetal rats.Other primary literatureAnimalActiveToxicology letters2024
Han H, Shi H, Jiang L, et al.
The caffeine dilemma: unraveling the intricate relationship between caffeine use disorder, caffeine withdrawal symptoms and mental well-being in adults.Other primary literatureHumanActivePublic health nutrition2024
Bodur M, Kaya S, Ilhan-Esgin M, et al.
How Does the Powder Mixture of Ibuprofen and Caffeine Attenuate the Solubility of Ibuprofen? Comparative Study for the Xanthine Derivatives to Recognize Their Intermolecular Interactions Using Fourier-Transform Infrared (FTIR) Spectra, Differential Scanning Calorimetry (DSC), and X-ray Powder Diffractometry (XRPD).Other primary literatureUnknownActiveMolecular pharmaceutics2024
Suenaga S, Kataoka H, Hasegawa K, et al.
A phase I trial of caffeine to evaluate safety in infants with hypoxic-ischemic encephalopathy.Other primary literatureHumanActiveJournal of perinatology : official journal of the California Perinatal Association2024
Jackson W, Gonzalez D, Greenberg RG, et al.
Caffeine pharmacokinetics following umbilical vein injection during delayed cord clamping in preterm lambs.Other primary literatureAnimalActivePediatric research2024
Zeinali L, Giusto E, Knych H, et al.
Caffeine supplementation improves the cognitive abilities and shooting performance of elite e-sports players: a crossover trial.Randomized controlled trialHumanActiveScientific reports2024
Wu SH, Chen YC, Chen CH, et al.
Estimate the prevalence of daily caffeine consumption, caffeine use disorder, caffeine withdrawal and perceived harm in Iran: a cross-sectional study.Other primary literatureHumanActiveScientific reports2024
Abdoli F, Davoudi M, Momeni F, et al.
Newly synthesized chitosan nanoparticles loaded with caffeine/moringa leaf extracts Halt Her2, BRCA1, and BRCA2 expressions.Other primary literatureHuman & animalActiveScientific reports2024
Mohammed H, Karhib MM, Al-Fahad KSJ, et al.
Association between coffee and caffeine intake and functional dyspepsia.Other primary literatureHumanActiveScientific reports2024
Koochakpoor G, Salari-Moghaddam A, Keshteli AH, et al.
Cost-effective eggshell-modified LDH composite for caffeine adsorption, cytotoxicity and antimicrobial activity: exploring the synergy and economic viability in search processes.Other primary literatureUnknownActiveRSC advances2024
Elrafey A, Farghali AA, Kamal W, et al.
Augmentation of Electroconvulsive Therapy with Oral Caffeine: A Retrospective Analysis of 40 Patients with Major Depression.Other primary literatureHumanActivePharmacopsychiatry2024
Nyhuis P, Mücke D, Specka M, et al.
Alcohol and Caffeine Co-Administration Increased Acetylcholinesterase Activity and Inflammatory Cytokines in Sleep-Deprived Rats: Implications for Cognitive Decline and Depressive-Like Manifestations.Other primary literatureUnknownActiveSleep science (Sao Paulo, Brazil)2024
Daubry TME, Nwogueze BC, Toloyai PY, et al.
Caffeine-loaded nano/micro-carriers: Techniques, bioavailability, and applications.ReviewHumanActiveCritical reviews in food science and nutrition2024
Shaddel R, Akbari-Alavijeh S, Cacciotti I, et al.
Marketable 1,3-dimethylamylamine and caffeine-based thermogenic supplements: Regulatory genotoxicity assessment through in vitro and in silico approaches.Other primary literatureHuman & animalActiveJournal of toxicology and environmental health. Part A2024
Carrão Dantas EK, Ferreira CLS, da Cunha Goldstein A, et al.
A novel multi-omics data analysis of dose-dependent and temporal changes in regulatory pathways due to chemical perturbation: a case study on caffeine.Other primary literatureUnknownActiveToxicology mechanisms and methods2024
Liu Y, Lian G, Chen T
Common questions and misconceptions about caffeine supplementation: what does the scientific evidence really show?ReviewHumanActiveJournal of the International Society of Sports Nutrition2024
Antonio J, Newmire DE, Stout JR, et al.
Comparative Bioavailability and Benefits on Mental Functions of Novel Extended-Release Caffeine Capsules against Immediate-Release Caffeine Capsules: An Open-Label, Randomized, Cross-over, Single-Dose Two-Way Crossover Study.Randomized controlled trialHumanActiveJournal of dietary supplements2024
Thanawala S, Shah R, Abiraamasundari R, et al.
A cost-effectiveness analysis for high versus standard (low) dose caffeine for the treatment of apnea in neonatal intensive care unit.Other primary literatureUnknownActiveJournal of pharmaceutical policy and practice2024
Al-Hersh E, Abushanab D, AbouNahia F, et al.
Ventricular fibrillation during football training as a consequence of kratom and caffeine use in an adolescent: case report.Other primary literatureUnknownActiveEuropean heart journal. Case reports2024
Dodulík J, Plášek J, Handlos P, et al.
Beyond the buzz: the fatal consequences of caffeine overconsumption.Other primary literatureHumanActiveJournal of analytical toxicology2024
Brower JO, Swatek JL
The role of caffeine in headache disorders.ReviewHumanActiveCurrent opinion in neurology2024
Charles A
Randomized comparison between a forced air system and warm water bath for resuscitation of neonatal hypothermic calves with or without oral administration of caffeine.Other primary literatureAnimalActiveJournal of veterinary internal medicine2024
Copeland AT, Kreuder AJ, Dewell G, et al.
Gastrointestinal effects of caffeine in preterm infants: a systematic review and Bayesian meta-analysis.Meta-analysisHumanActiveArchives of disease in childhood. Fetal and neonatal edition2024
Gama B, von Hafe M, Vieira R, et al.
Impact of early caffeine administration on respiratory outcomes in very preterm infants initially receiving invasive mechanical ventilation.Observational studyHumanActiveBMJ open respiratory research2024
Zhao Y, Zhang L, Zhang M, et al.
Optical Coherence Tomography Angiography: Investigating Vessel Density Changes Induced by Caffeine in Healthy Subjects.Other primary literatureUnknownActiveJournal of ophthalmology2024
Jacobs M, Demas N, Hemesath A, et al.
High Doses of Caffeine-Induced Cerebral Infarction Leading to Partial Locked-In Syndrome in a Young Adult: A Novel Association?Other primary literatureUnknownActiveCase reports in neurology2024
Sinha V, Lam L, Nguyen MV
Perinatal Caffeine Administration Improves Outcomes in an Ovine Model of Neonatal Hypoxia-Ischemia.Other primary literatureAnimalActiveStroke2024
Mike JK, White Y, Ha J, et al.
Acute Effects of Oral Caffeine Intake on Human Global-Flash mfERG Responses: A Placebo-Controlled, Double-Masked, Balanced Crossover Study.Randomized controlled trialHumanActiveInvestigative ophthalmology & visual science2024
Vera J, Redondo B, Vera-Diaz FA, et al.
Association of Caffeine Daily Dose With Respiratory Outcomes in Preterm Neonates: A Retrospective Cohort Study.Other primary literatureHumanActiveInquiry : a journal of medical care organization, provision and financing2024
Rauf S, Shah S, Bibi Z, et al.
Relationship Between Caffeine Consumption and Young Athletes' Comorbidities, Exercise-Related Symptoms, and Baseline Electrocardiogram.Other primary literatureHumanActiveSports health2024
Farber J, Dikdan S, Ruge M, et al.
Non-oliguric acute renal failure secondary to a potentially lethal dose of caffeine with acute intoxication: a case report.Other primary literatureHumanActiveBMC nephrology2024
Mitomo A, Ishioka K, Yanai M, et al.
Predictors for poor daily weight gain in preterm neonates exposed to different dose regimens of caffeine in ICU- a retrospective cohort study.Other primary literatureHumanActiveBMC pediatrics2024
Ahmed S, Rehman AU, Bibi Z, et al.
Effects of caffeine on accelerometer measured sleep and physical activity among older adults under free-living conditions.Other primary literatureHumanActiveBMC public health2024
Sakal C, Zhao W, Xu W, et al.
Caffeine intake is nonlinearly associated with muscle mass in young and middle-aged US adults.Other primary literatureHumanActiveBMC musculoskeletal disorders2024
Zhou L, Qu H, Wang J, et al.
Genetic susceptibility to caffeine intake and metabolism: a systematic review.Systematic reviewHumanActiveJournal of translational medicine2024
Low JJ, Tan BJ, Yi LX, et al.
Simultaneously quantifying a novel five-component anti- migraine formulation containing ergotamine, propyphenazone, caffeine, camylofin, and mecloxamine using UV spectrophotometry and chemometric models.Other primary literatureUnknownActiveBMC chemistry2024
Abbas AEF, Abdelshafi NA, Gamal M, et al.
Association of caffeine intake with all-cause and cardiovascular mortality in diabetes and prediabetes.Other primary literatureUnknownActiveDiabetology & metabolic syndrome2024
Yao H, Li L, Wang X, et al.
Translation and validation of the caffeine use disorder questionnaire in Arabic.Other primary literatureUnknownActiveArchives of public health = Archives belges de sante publique2024
Fekih-Romdhane F, Hallit R, Malaeb D, et al.
Association between caffeine intake and erectile dysfunction: a meta-analysis of cohort studies.Meta-analysisHumanActiveJournal of health, population, and nutrition2024
Karimi M, Asbaghi O, Kazemi K, et al.
Motives for Caffeine Consumption Questionnaire (MCCQ): validity and reliability of Turkish version.Other primary literatureUnknownActivePsicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS2024
Küçükkasap T, Uslu B
A landscape evaluation of caffeine citrate availability and use in newborn care across five low- and middle-income countries.Other primary literatureUnknownActivePLOS global public health2024
Ekhaguere OA, Bolaji O, Nabwera HM, et al.
Potential efficacy of caffeine ingestion on balance and mobility in patients with multiple sclerosis: Preliminary evidence from a single-arm pilot clinical trial.Other primary literatureHumanActivePloS one2024
Dadvar A, Jameie M, Azizmohammad Looha M, et al.
Caffeine mitigates tamoxifen-induced fatty liver in Wistar rats.Other primary literatureAnimalActiveActa cirurgica brasileira2024
Sezgin Y, Bora ES, Arda DB, et al.
Simultaneous analysis of caffeine and paraxanthine provides potentially useful indexes in the treatment of acute caffeine intoxication.Other primary literatureHumanActiveThe Journal of toxicological sciences2024
Yamazaki Y, Kaizaki-Mitsumoto A, Sato M, et al.
Caffeine in Hepatocellular Carcinoma: Cellular Assays, Animal Experiments, and Epidemiological Investigation.ReviewUnknownActiveJournal of inflammation research2024
Shan L, Zhao N, Wang F, et al.
Caffeine Intoxication, in Which the Theophylline Level Served as an Indicator of the Treatment Course and the Caffeine Level Could Be Measured.Other primary literatureHumanActiveInternal medicine (Tokyo, Japan)2024
Yoshimine N, Oba N, Hasegawa C, et al.
Impact of Caffeine Intake Strategies on Heart Rate Variability during Post-Exercise Recovery: A Systematic Review and Meta-Analysis.Meta-analysisHumanActiveCurrent cardiology reviews2024
Almeida BA, Morales AP, Ribeiro JRC, et al.
Preparation and evaluation of hair growth promoting effect of transferosomes containing red clover extract and caffeine alone or in combination.Other primary literatureUnknownActiveAvicenna journal of phytomedicine2024
Hajhashemi V, Taheri A, Karimian F, et al.
Effects of dose-dependent chronic caffeine consumption in a rat burn wound model: Histopathological and immunohistochemical evaluation.Other primary literatureUnknownActiveIranian journal of basic medical sciences2024
Yilmaz F, Aydemi R S, Yilmaz B, et al.
What is more common in fatal caffeine intoxication - suicide or unintentional overdose?ReviewHumanActiveArhiv za higijenu rada i toksikologiju2024
Lušić D, Bezak S, Karačonji IB
Effect of Acute Administration of Caffeine on Neuropathic Pain and the Role of Nitric Oxide Pathway in an Animal Model of Chronic Constriction Injury.Other primary literatureUnknownActiveBasic and clinical neuroscience2024
Naderi Tehrani M, Hamidi GA, Heydari A, et al.
Ad libitum caffeine consumption, cognitive performance, and sleep in special forces soldiers during a 96-h combat exercise.Other primary literatureUnknownActiveFrontiers in neuroscience2024
Erez D, Lieberman HR, Baum I, et al.
Caffeine improves mitochondrial dysfunction in the white matter of neonatal rats with hypoxia-ischemia through deacetylation: a proteomic analysis of lysine acetylation.Other primary literatureUnknownActiveFrontiers in molecular neuroscience2024
Zhang Y, Wang Y, Dou H, et al.
Combined effects of Rhodiola rosea and caffeine supplementation on aerobic endurance and muscle explosiveness: a synergistic approach.Other primary literatureUnknownActiveFrontiers in nutrition2024
Yun H, Lu B, Su W, et al.
Effect of caffeine intake on self-reported and genetic prediction of osteoarthritis: an epidemiological study and Mendelian randomization analysis.Other primary literatureUnknownActiveFrontiers in nutrition2024
Ji Z, Shen Y, Chen D, et al.
Comparative study of Saudi and Turkish coffee consumption in Saudi Arabia: insights into sociodemographic factors and caffeine intake.Other primary literatureUnknownActiveFrontiers in nutrition2024
Bawazeer NM, Binsunaid F, Alraqea A, et al.
Dietary caffeine and its negative link to serum Klotho concentrations: evidence from the National Health and Nutrition Examination Survey.Other primary literatureUnknownActiveFrontiers in nutrition2024
Wu H, Lu P
Exploring the association between caffeine intake and benign prostatic hyperplasia: results from the NHANES 2005-2008.Other primary literatureUnknownActiveFrontiers in nutrition2024
Zhang F, Zhang A, Tao J, et al.
Association between PER and CRY gene polymorphisms and the response to caffeine citrate treatment in infants with apnea of prematurity.Other primary literatureUnknownActiveFrontiers in pediatrics2024
Xie JB, Zhuang W, Zhu Y, et al.
The effects of aerobic exercise and heat stress on the unbound fraction of caffeine.Other primary literatureUnknownActiveFrontiers in physiology2024
McLaughlin M, Dizon K, Jacobs I
Enhancing water stress tolerance of bread wheat during seed germination and seedling emergence: caffeine-induced modulation of antioxidative defense mechanisms.Other primary literatureUnknownActiveFrontiers in plant science2024
Ali Q, Perveen R, Saeed F, et al.
Caffeine improves the shooting performance and reaction time of first-person shooter esports players: a dose-response study.Other primary literatureUnknownActiveFrontiers in sports and active living2024
Rogers EJ, Trotter MG, Johnson D, et al.
Transfer of Caffeine and Its Major Metabolites to Chicken Eggs.Other primary literatureUnknownActiveAnimals : an open access journal from MDPI2024
Teixeira MDS, Saraiva CJC, Dos Santos BP, et al.
Caffeine: The Story beyond Oxygen-Induced Lung and Brain Injury in Neonatal Animal Models-A Narrative Review.ReviewUnknownActiveAntioxidants (Basel, Switzerland)2024
Endesfelder S
Effects of Caffeine, Zinc, and Their Combined Treatments on the Growth, Yield, Mineral Elements, and Polyphenols of Solanum lycopersicum L.Other primary literatureUnknownActiveAntioxidants (Basel, Switzerland)2024
Vichi E, Francini A, Raffaelli A, et al.
Impacts of Self-Administered 3,4-Methylenedioxypyrovalerone (MDPV) Alone, and in Combination with Caffeine, on Recognition Memory and Striatal Monoamine Neurochemistry in Male Sprague Dawley Rats: Comparisons with Methamphetamine and Cocaine.Other primary literatureUnknownActiveBrain sciences2024
Seaman RW Jr, Lamon K, Whitton N, et al.
Effects of Various Caffeine Doses on Cognitive Abilities in Female Athletes with Low Caffeine Consumption.Other primary literatureUnknownActiveBrain sciences2024
Bougrine H, Ammar A, Salem A, et al.
Acute Effects of Caffeine Ingestion on Postural Balance, Functional Capacity and Cognitive Function in Patients with End Stage Renal Disease.Other primary literatureUnknownActiveBrain sciences2024
Hassen HBH, Ammar A, Machfer A, et al.
The Effect of Caffeine Exposure on Sleep Patterns in Zebrafish Larvae and Its Underlying Mechanism.Other primary literatureUnknownActiveClocks & sleep2024
Wei Y, Miao Z, Ye H, et al.
Matcha Green Tea: Chemical Composition, Phenolic Acids, Caffeine and Fatty Acid Profile.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2024
Kika J, Jakubczyk K, Ligenza A, et al.
Elimination of Toxic Solvents from Analytical Methods in Food Analysis: Caffeine Determination in Tea as an Example.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2024
Kalisz O, Jaworska A, Studzińska S, et al.
Optimization of the Microwave-Assisted Extraction of Caffeine from Roasted Coffee Beans.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2024
Savić IM, Savić Gajić IM, Gajić DG
The Babyccino: The Role of Caffeine in the Prevention of Acute Kidney Injury in Neonates-A Literature Review.ReviewUnknownActiveHealthcare (Basel, Switzerland)2024
Aithal N, Kandasamy Y
Silver and Gold Complexes with NHC-Ligands Derived from Caffeine: Catalytic and Pharmacological Activity.Other primary literatureHumanActiveInternational journal of molecular sciences2024
Mariconda A, Iacopetta D, Sirignano M, et al.
Effect of Caffeine on the Inflammatory-Dependent Changes in the GnRH/LH Secretion in a Female Sheep Model.Other primary literatureAnimalActiveInternational journal of molecular sciences2024
Herman AP, Tomczyk M, Wójcik M, et al.
TRPA1, TRPV1, and Caffeine: Pain and Analgesia.ReviewHuman & animalActiveInternational journal of molecular sciences2024
Puthumana EA, Muhamad L, Young LA, et al.
Caffeine Protects Keratinocytes from Trichophyton mentagrophytes Infection and Behaves as an Antidermatophytic Agent.Other primary literatureHumanActiveInternational journal of molecular sciences2024
da Fonseca DM, Rodrigues L, Sousa-Baptista J, et al.
The Effects of Caffeine on Blood Platelets and the Cardiovascular System through Adenosine Receptors.ReviewHuman & animalActiveInternational journal of molecular sciences2024
Marcinek K, Luzak B, Rozalski M
The Bifunctional Dimer Caffeine-Indan Attenuates α-Synuclein Misfolding, Neurodegeneration and Behavioral Deficits after Chronic Stimulation of Adenosine A1 Receptors.Other primary literatureAnimalActiveInternational journal of molecular sciences2024
Jakova E, Aigbogun OP, Moutaoufik MT, et al.
Colchicine, Caffeine, Gramine, and Their Derivatives as Potential Herbicides, Fungicides, and Insecticides.Other primary literatureAnimalActiveInternational journal of molecular sciences2024
Kurek J, Sierakowska A, Berdzik N, et al.
Caffeine: A Multifunctional Efficacious Molecule with Diverse Health Implications and Emerging Delivery Systems.ReviewHuman & animalActiveInternational journal of molecular sciences2024
Song X, Singh M, Lee KE, et al.
Nanotechnology-Driven Delivery of Caffeine Using Ultradeformable Liposomes-Coated Hollow Mesoporous Silica Nanoparticles for Enhanced Follicular Delivery and Treatment of Androgenetic Alopecia.Other primary literatureHuman & animalActiveInternational journal of molecular sciences2024
Thepphankulngarm N, Manmuan S, Hirun N, et al.
Self-Reported Gastrointestinal Symptoms Associated with NSAIDs and Caffeine Consumption in a Jordanian Subpopulation.Other primary literatureHumanActiveMedicina (Kaunas, Lithuania)2024
Al Shboul S, Maloul O, Al-Trad H, et al.
Silver and Copper Complexes with Ibuprofen and Caffeine-Preparation and Evaluation of Their Selected Biological Effects.Other primary literatureHumanActiveMolecules (Basel, Switzerland)2024
Borówka A, Sierosławska A, Baier A, et al.
Green Processing of Ilex guayusa: Antioxidant Concentration and Caffeine Reduction Using Encapsulation by Supercritical Antisolvent Process.Other primary literatureUnknownActiveMolecules (Basel, Switzerland)2024
Meneses MÁ, Guzmán J, Cabrera J, et al.
Diagnostic Ultrasound-Based Investigation of Central vs. Peripheral Arterial Changes Consequent to Low-Dose Caffeine Ingestion.Other primary literatureHumanActiveNutrients2024
Jin YB, Kim JH, Song CH, et al.
The Effect of Post-Activation Potentiation Enhancement Alone or in Combination with Caffeine on Anaerobic Performance in Boxers: A Double-Blind, Randomized Crossover Study.Randomized controlled trialHumanActiveNutrients2024
Zhang Y, Zhang Y, Diao P, et al.
Belief That Caffeine Ingestion Improves Performance in a 6-Minute Time Trial Test without Affecting Pacing Strategy.Other primary literatureHumanActiveNutrients2024
Valero F, González-Mohíno F, Salinero JJ
Optimizing Short-Term Maximal Exercise Performance: The Superior Efficacy of a 6 mg/kg Caffeine Dose over 3 or 9 mg/kg in Young Female Team-Sports Athletes.Randomized controlled trialHumanActiveNutrients2024
Bougrine H, Ammar A, Salem A, et al.
The Effect of Creatine Nitrate and Caffeine Individually or Combined on Exercise Performance and Cognitive Function: A Randomized, Crossover, Double-Blind, Placebo-Controlled Trial.Randomized controlled trialHumanActiveNutrients2024
Mabrey G, Koozehchian MS, Newton AT, et al.
Daily Caffeine Consumption May Increase the Risk of Acute Kidney Injury Related to Platinum-Salt Chemotherapy in Thoracic Cancer Patients: A Translational Study.Other primary literatureHuman & animalActiveNutrients2024
Hamroun A, Decaestecker A, Larrue R, et al.
Methionine Supplementation Alleviates the Germ Cell Apoptosis Increased by Maternal Caffeine Intake in a C. elegans Model.Other primary literatureAnimalActiveNutrients2024
Min H, Kim J, Lee M, et al.
Change in Caffeine Consumption after Pandemic (CCAP-Study) among University Students: A Cross-Sectional Study from Italy.Other primary literatureHumanActiveNutrients2024
Di Martino G, Di Giovanni P, Vaccaro F, et al.
Effects of Acute Ingestion of Caffeine Capsules on Muscle Strength and Muscle Endurance: A Systematic Review and Meta-Analysis.Meta-analysisHumanActiveNutrients2024
Wu W, Chen Z, Zhou H, et al.
Placebo Effect of Caffeine on Physiological Parameters and Physical Performance.Randomized controlled trialHumanActiveNutrients2024
Ortiz-Sánchez D, Bravo-Sánchez A, Ramírez-delaCruz M, et al.
Timing Matters: Time of Day Impacts the Ergogenic Effects of Caffeine-A Narrative Review.ReviewHumanActiveNutrients2024
Zhang Y, Yang W, Xue Y, et al.
Effects of Different Caffeine Dosages on Maximal Physical Performance and Potential Side Effects in Low-Consumer Female Athletes: Morning vs. Evening Administration.Randomized controlled trialHumanActiveNutrients2024
Bougrine H, Ammar A, Salem A, et al.
Combined Impact of Creatine, Caffeine, and Variable Resistance on Repeated Sprint Ability in Young Soccer Players.Randomized controlled trialHumanActiveNutrients2024
Huerta Ojeda Á, Jorquera-Aguilera C
Impact of CYP1A2 Genotypes on the Ergogenic Effects and Subjective Mood States of Caffeine Ingestion in Resistance-Trained Women.Randomized controlled trialHumanActiveNutrients2024
Prather JM, Florez CM, Vargas A, et al.
The Effect of a Caffeine and Nicotine Combination on Nicotine Withdrawal Syndrome in Mice.Other primary literatureAnimalActiveNutrients2024
Chen Z, Lu N, Li X, et al.
Caffeine Intake Alters Recovery Sleep after Sleep Deprivation.Randomized controlled trialHumanActiveNutrients2024
Pauchon B, Beauchamps V, Gomez-Mérino D, et al.
The Effects of Caffeine on Exercise in Hot Environments: A Bibliometric Study.ReviewHumanActiveNutrients2024
Li H, Yang Y, Liu Q, et al.
Caffeine Enhances Some Aspects of Physical Performance in Well-Trained Hammer and Discus Throwers.Randomized controlled trialHumanActiveNutrients2024
Gallo-Salazar C, Del Coso J, Lara B, et al.
Mid-Infrared Photothermal Spectroscopy for the Detection of Caffeine in Beverages.Other primary literatureHumanActiveSensors (Basel, Switzerland)2024
Ricchiuti G, Riedlsperger L, Dabrowska A, et al.
Pre-Exercise Caffeine and Sodium Bicarbonate: Their Effects on Isometric Mid-Thigh Pull Performance in a Crossover, Double-Blind, Placebo-Controlled Study.Other primary literatureUnknownActiveSports (Basel, Switzerland)2024
Kaçoğlu C, Kirkaya İ, Ceylan Hİ, et al.
Caffeine and Arrhythmias: A Critical Analysis of Cardiovascular Responses and Arrhythmia Susceptibility.ReviewUnknownActiveJournal of the Saudi Heart Association2024
Hamad AKS
Caffeine consumption of medical students in Korea: amount and symptoms based on a 2023 survey.Other primary literatureHumanActiveKorean journal of medical education2024
Choi SW, Kim YW, Lee CY, et al.
Patterns of caffeine consumption among medical undergraduates in Secunderabad, Telangana, India.Other primary literatureUnknownActiveJournal of education and health promotion2024
Pulla A, Syed A, Bolisetti V
Caffeine and Vision: Effects on the Eye.ReviewHumanActiveTurkish journal of ophthalmology2024
Yan A, La Rosa A, Chhablani PP, et al.
Anti-aging and immunomodulatory role of caffeine in Drosophila larvae.Other primary literatureAnimalActiveNarra J2024
Nainu F, Sartini S, Bahar MA, et al.
Motor improvement in Parkinson's disease patients receiving caffeine adjuvants: A double-blind randomized controlled trial in Indonesia.Randomized controlled trialHumanActiveNarra J2024
Hamdan M, Suharto AP, Nugraha P, et al.
Caffeine attenuates spermatogenic disorders in mice with induced chronic scrotal hyperthermia.Other primary literatureUnknownActiveClinical and experimental reproductive medicine2024
Raoofi A, Gholami O, Mokhtari H, et al.
Sleep, Caffeine, BMI, and Pressure Pain Threshold in Temporomandibular Disorder Patients: An Observational Study.Other primary literatureUnknownActiveCureus2024
Al-Khudhairy MW, Alkhamsi Alqahtani GB, Altwijri AMA, et al.
Frequency and Amount of Caffeine Consumption and Its Effects on Sleep Quality Among the General Population in Makkah City, Saudi Arabia, in 2024.Other primary literatureUnknownActiveCureus2024
Khan RM, Alqurashi J
Caffeine-Induced Psychosis: A Case Report and Review of Literature.Other primary literatureUnknownActiveCureus2024
Mannix D, Mulholland K, Byrne F
Death Due to Caffeine and Methamphetamine Toxicity: A Case Report.Other primary literatureUnknownActiveCureus2024
Kim DG, Powers S, Gitto L
[CAFFEINE POISONING AND FATAL ARRHYTHMIAS: A CASE REPORT].Other primary literatureHumanActiveHarefuah2024
Ganayem M, Kostantin N, Daskal Y, et al.
Compatibility of Caffeine Clobetasol Propionate Dutasteride Nicotinamide and Progesterone in TrichoFoam™, a Natural Vehicle for Hair Foams.Other primary literatureHumanActiveInternational journal of pharmaceutical compounding2024
Polonini HC, de Sousa PL, Silva CC, et al.
Caffeine dosing regimens in preterm infants with or at risk for apnea of prematurity.ReviewHumanActiveThe Cochrane database of systematic reviews2023
Bruschettini M, Brattström P, Russo C, et al.
Caffeine versus other methylxanthines for the prevention and treatment of apnea in preterm infants.ReviewHumanActiveThe Cochrane database of systematic reviews2023
Moresco L, Sjögren A, Marques KA, et al.
A case of caffeine intoxication resulting in hypothermia.Other primary literatureUnknownActiveClinical case reports2023
Ohno T, Katsuki S, Miyamoto K, et al.
Use of haemodiafiltration in the treatment of massive caffeine intoxication in a dog.Other primary literatureAnimalActiveVeterinary medicine and science2023
Gordon DS, Langston CE
A Tiered Ecological Risk Assessment of Caffeine by Using Species Sensitivity Distribution Method in the Nansi Lake Basin.Other primary literatureUnknownActiveBulletin of environmental contamination and toxicology2023
Zheng L, Zhang J, Wu Y, et al.
Effect of alpha-lipoic acid and caffeine-loaded chitosan nanoparticles on obesity and its complications in liver and kidney in rats.Other primary literatureAnimalActiveNaunyn-Schmiedeberg's archives of pharmacology2023
Sawie HG, Khadrawy YA, El-Gizawy MM, et al.
Effect of caffeine intake on fat oxidation rate during exercise: is there a dose-response effect?Randomized controlled trialHumanActiveEuropean journal of nutrition2023
Gutiérrez-Hellín J, Aguilar-Navarro M, Ruiz-Moreno C, et al.
Effect of isolated and combined ingestion of caffeine and citrulline malate on resistance exercise and jumping performance: a randomized double-blind placebo-controlled crossover study.Randomized controlled trialHumanActiveEuropean journal of nutrition2023
Haugen ME, Vårvik FT, Grgic J, et al.
Effects of resistance exercise alone or with caffeine on hemodynamics, autonomic modulation and arterial stiffness in resistance-trained women.Randomized controlled trialHumanActiveEuropean journal of applied physiology2023
Parks JC, Joplin MCP, Marshall EM, et al.
The striatum drives the ergogenic effects of caffeine.Other primary literatureHuman & animalActivePurinergic signalling2023
de Bem Alves AC, Speck AE, Farias HR, et al.
Nicotine, alcohol, and caffeine use among individuals with untreated obstructive sleep apnea.Other primary literatureHumanActiveSleep & breathing = Schlaf & Atmung2023
Baldassarri SR, Chu JH, Deng A, et al.
Effects of environmental concentrations of caffeine on adult zebrafish behaviour: a short-term exposure scenario.Other primary literatureAnimalActiveEnvironmental science and pollution research international2023
Santos N, Picolo V, Domingues I, et al.
Influence of exposure scenario on the sensitivity to caffeine.Other primary literatureAnimalActiveEnvironmental science and pollution research international2023
Santos N, Oliveira M, Domingues I
Buccal caffeine strips for reversal of adverse symptoms of vasodilator stress.Other primary literatureHumanActiveJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2023
Elsadany M, Stringer B, Bote J, et al.
Enteral and Parenteral Treatment with Caffeine for Preterm Infants in the Delivery Room: A Randomised Trial.Randomized controlled trialHumanCorrectedPaediatric drugs2023
Dani C, Cecchi A, Ciarcià M, et al.
Protective effects of caffeine against palmitate-induced lipid toxicity in primary rat hepatocytes is associated with modulation of adenosine receptor A1 signaling.Other primary literatureAnimalActiveBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2023
Arroyave-Ospina JC, Buist-Homan M, Schmidt M, et al.
Fiberglass cloth coated by coffee ground waste-derived carbon quantum dots/titanium dioxide composite for removal of caffeine and other pharmaceuticals from water.Other primary literatureUnknownActiveHeliyon2023
Muangmora R, Kemacheevakul P, Chuangchote S
Insights into environmental caffeine contamination in ecotoxicological biomarkers and potential health effects of Danio rerio.Other primary literatureUnknownActiveHeliyon2023
Diogo BS, Antunes SC, Pinto I, et al.
Alcohol and caffeine synergistically induce spontaneous ventricular tachyarrhythmias: ameliorated with dantrolene treatment.Other primary literatureUnknownActiveHeart rhythm O22023
Zhang Y, Kim C, Wasif N, et al.
3D printing tablets for high-precision dose titration of caffeine.Other primary literatureHumanActiveInternational journal of pharmaceutics2023
Krueger L, Cao Y, Zheng Z, et al.
Interaction of CYP3A4 with caffeine: First insights into multiple substrate binding.Other primary literatureHumanActiveThe Journal of biological chemistry2023
Sevrioukova IF
Prediction of herb-drug interactions involving consumption of furanocoumarin-mixtures and cytochrome P450 1A2-mediated caffeine metabolism inhibition in humans.Other primary literatureUnknownActiveSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2023
Alehaideb Z
Acute toxicity of triclosan, caffeine, nanoplastics, microplastics, and their mixtures on Daphnia magna.Other primary literatureAnimalActiveMarine pollution bulletin2023
Pashaei R, Dzingelevičienė R, Putna-Nimane I, et al.
Development of a trace quantitative method to investigate caffeine distribution in the Yellow and Bohai Seas, China, and assessment of its potential neurotoxic effect on fish larvae.Other primary literatureAnimalActiveMarine pollution bulletin2023
Yan Z, Li Y, Lin A, et al.
OpiCa1-PEG-PLGA nanomicelles antagonize acute heart failure induced by the cocktail of epinephrine and caffeine.Other primary literatureUnknownActiveMaterials today. Bio2023
Li J, Wang F, Liu X, et al.
Theophylline reverses oxycodone's but not fentanyl's respiratory depression in mice while caffeine is ineffective against both opioids.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior2023
Elder HJ, Walentiny DM, Beardsley PM
Caffeine levels and dietary intake in smokers with schizophrenia and bipolar disorder.Other primary literatureHumanActivePsychiatry research2023
Rosen RL, Ramasubramani RS, Benowitz NL, et al.
Integrative approach to elucidate the embryological effects of caffeine in Cyprinus carpio: Bioconcentration and alteration of oxidative stress-related gene expression patterns.Other primary literatureAnimalActiveThe Science of the total environment2023
Casas-Hinojosa I, Gómez-Oliván LM, Gutierrez-Noya VM, et al.
Preclinical Pharmacokinetic Study on Caffeine as an Excipient for Monoclonal Antibody Formulations.Other primary literatureAnimalActiveJournal of pharmaceutical sciences2023
Zeng Y, Naik S, Tran T, et al.
The relationship between caffeine and its metabolites and bone mineral density in postmenopausal women: a cross-sectional analysis from the NHANES database.Other primary literatureHumanActiveJournal of nutritional science2023
Liao S, Zhou J, Chen H, et al.
Effects of front-of-package caffeine and sweetener disclaimers in Mexico: cross-sectional results from the 2020 International Food Policy Study.Other primary literatureHumanActivePublic health nutrition2023
Arellano-Gómez LP, Jáuregui A, Nieto C, et al.
Caffeine and Cationic Copolymers with Antimicrobial Properties.Other primary literatureUnknownActiveACS bio & med chem Au2023
Salas-Ambrosio P, Vexler S, P S R, et al.
Mono- and Multicomponent Biosorption of Caffeine and Salicylic Acid onto Processed Cape Gooseberry Husk Agri-Food Waste.Other primary literatureUnknownActiveACS omega2023
Abdel Salam J, Saleh AA, El Nenaiey TT, et al.
Synthesis and Evaluation of Alginate-Based Nanogels as Sustained Drug Carriers for Caffeine.Other primary literatureUnknownActiveACS omega2023
Suhail M, Fang CW, Chiu IH, et al.
Mechanochemical Degradation of Caffeine and Diclofenac Using Biochar of Fique Bagasse in the Presence of Al: Monitoring by Mass Spectrometry.Other primary literatureUnknownActiveACS omega2023
Correa-Navarro YM, López GD, Carazzone C, et al.
Twin study of caffeine use, ADHD, and disrupted sleep in ABCD youth.Other primary literatureHumanActiveHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2023
Dash GF, Carter E, Karalunas SL, et al.
Weight-adjusted caffeine and β-blocker use in novice versus senior retina surgeons: a self-controlled study of simulated performance.Randomized controlled trialHumanActiveEye (London, England)2023
Roizenblatt M, Gehlbach PL, da Silveira Saraiva V, et al.
Effects of caffeine and blue-enriched light on spare visual attention during simulated space teleoperation.Other primary literatureUnknownActiveNPJ microgravity2023
Liu AM, Galvan-Garza RC, Flynn-Evans EE, et al.
Brain activity during a working memory task after daily caffeine intake and caffeine withdrawal: a randomized double-blind placebo-controlled trial.Randomized controlled trialHumanActiveScientific reports2023
Lin YS, Weibel J, Landolt HP, et al.
New C8-substituted caffeine derivatives as promising antioxidants and cytoprotective agents in human erythrocytes.Other primary literatureHumanActiveScientific reports2023
Sierakowska A, Jasiewicz B, Piosik Ł, et al.
Serum caffeine concentrations in preterm infants: a retrospective study.Observational studyHumanActiveScientific reports2023
Sugino M, Kuboi T, Noguchi Y, et al.
Association between urinary caffeine and caffeine metabolites and stroke in American adults: a cross-sectional study from the NHANES, 2009-2014.Other primary literatureHumanActiveScientific reports2023
Fan J, Yuan Y, Zhang X, et al.
Effect of caffeine and other xanthines on liver sinusoidal endothelial cell ultrastructure.Other primary literatureAnimalActiveScientific reports2023
Mao H, Szafranska K, Kruse L, et al.
Caffeine exacerbates seizure-induced death via postictal hypoxia.Other primary literatureHuman & animalActiveScientific reports2023
George AG, Federico A, Gom RC, et al.
Caffeine and Less Invasive Surfactant Administration for Respiratory Distress Syndrome of the Newborn.Other primary literatureHumanActiveNEJM evidence2023
Katheria A, Ines F, Banerji A, et al.
Evaluation of subchronic toxicity of the compound of diphenhydramine hydrochloride and caffeine after 28 days of repeated oral administration in Sprague-Dawley rats and beagle dogs.Other primary literatureAnimalActiveDrug and chemical toxicology2023
Ren L, Yan L, Shi W, et al.
Dietary sources, health benefits, and risks of caffeine.ReviewHumanActiveCritical reviews in food science and nutrition2023
Saimaiti A, Zhou DD, Li J, et al.
Genotoxic effects of caffeine in female mice exposed during pregnancy and lactation period and their offspring.Other primary literatureAnimalActiveJournal of environmental science and health. Part C, Toxicology and carcinogenesis2023
Lummertz Magenis M, Souza de Marcos P, Paganini Damiani A, et al.
Deeply functional identification of TCS1 alleles provides efficient technical paths for low-caffeine breeding of tea plants.Other primary literatureUnknownActiveHorticulture research2023
Wang Y, Liu YF, Wei MY, et al.
Objective measures of smoking and caffeine intake and the risk of adverse pregnancy outcomes.Other primary literatureHumanActiveInternational journal of epidemiology2023
Selvaratnam RJ, Sovio U, Cook E, et al.
Utilizing a cell-free protein synthesis platform for the biosynthesis of a natural product, caffeine.Other primary literatureUnknownActiveSynthetic biology (Oxford, England)2023
Ditzel A, Zhao F, Gao X, et al.
Occipital Nerve Block Compared With Acetaminophen and Caffeine for Headache Treatment in Pregnancy: A Randomized Controlled Trial.Randomized controlled trialHumanActiveObstetrics and gynecology2023
Bushman ET, Blanchard CT, Cozzi GD, et al.
Nutrients mediate caffeine inhibition of Escherichia coli.Other primary literatureHumanActiveEnvironmental microbiology reports2023
McConnell MN, Bakermans C
Effect of capmatinib on the pharmacokinetics of substrates of CYP3A (midazolam) and CYP1A2 (caffeine) in patients with MET-dysregulated solid tumours.Other primary literatureHumanActiveBritish journal of clinical pharmacology2023
Chen X, Isambert N, López-López R, et al.
Caffeine intoxication treated with hemodialysis.Other primary literatureHumanActiveSeminars in dialysis2023
Khan S, Babu K, Sidhu R, et al.
Caffeine to prevent intermittent hypoxaemia in late preterm infants: randomised controlled dosage trial.Randomized controlled trialHumanActiveArchives of disease in childhood. Fetal and neonatal edition2023
Oliphant EA, McKinlay CJ, McNamara D, et al.
Oral administration of caffeine metabolite 7-methylxanthine is associated with slowed myopia progression in Danish children.Other primary literatureHumanActiveThe British journal of ophthalmology2023
Trier K, Cui D, Ribel-Madsen S, et al.
Caffeine, Postoperative Delirium And Change In Outcomes after Surgery (CAPACHINOS)-2: protocol for a randomised controlled trial.Other primary literatureHumanActiveBMJ open2023
Vlisides PE, Ragheb J, McKinney A, et al.
Limited caffeine consumption as first-line treatment in managing primary monosymptomatic enuresis in children: how effective is it? A randomised clinical trial.Randomized controlled trialHumanActiveBMJ paediatrics open2023
Rezakhaniha S, Rezakhaniha B, Siroosbakht S
Determination of Caffeine, Theobromine, and Theophylline by HPLC-DAD in Beverages Commonly Consumed in Lima, Peru.Other primary literatureUnknownActiveInternational journal of food science2023
Gonzales-Yépez KA, Vilela JL, Reátegui O
Nephroprotective Effects of Caffeine, Vanillin, and Their Combination against Experimental AlCl3-Induced Renal Toxicity in Adult Male Wistar Rats.Other primary literatureUnknownActiveBiochemistry research international2023
Afolabi OB, Olasehinde OR, Olaoye OA, et al.
Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma.Other primary literatureHuman & animalActiveCancer research2023
Tran GB, Ding J, Ye B, et al.
Effects of modafinil and caffeine on night-time vigilance of air force crewmembers: A randomized controlled trial.Randomized controlled trialHumanActiveJournal of psychopharmacology (Oxford, England)2023
Wingelaar-Jagt YQ, Bottenheft C, Riedel WJ, et al.
Reduction in caffeine withdrawal after open-label decaffeinated coffee.Randomized controlled trialHumanActiveJournal of psychopharmacology (Oxford, England)2023
Mills L, Lee JC, Boakes R, et al.
Rapid emergence from dexmedetomidine sedation in Sprague Dawley rats by repurposing an α2-adrenergic receptor competitive antagonist in combination with caffeine.Other primary literatureAnimalActiveBMC anesthesiology2023
Xie Z, Fox AP
Caffeine-folic acid-loaded-chitosan nanoparticles combined with methotrexate as a novel HepG2 immunotherapy targeting adenosine A2A receptor downstream cascade.Other primary literatureHumanActiveBMC complementary medicine and therapies2023
Hamed A, Ghareeb D, Mohamed TM, et al.
Smart chemometrics-assisted spectrophotometric methods for efficient resolution and simultaneous determination of paracetamol, caffeine, drotaverine HCl along with three of their corresponding related impurities.Other primary literatureUnknownActiveBMC chemistry2023
Tawfik SA, Hegazy MA, El-Ragehy NA, et al.
Caffeine ameliorates the metabolic syndrome in diet-induced obese mice through regulating the gut microbiota and serum metabolism.Other primary literatureUnknownActiveDiabetology & metabolic syndrome2023
Chen L, Wang XJ, Chen JX, et al.
Caffeine activates HOG-signalling and inhibits pseudohyphal growth in Saccharomyces cerevisiae.Other primary literatureHumanActiveBMC research notes2023
Elhasi T, Blomberg A
Developing and testing a clinical care bundle incorporating caffeine citrate to manage apnoea of prematurity in a resource-constrained setting: a mixed methods clinical feasibility study protocol.Other primary literatureUnknownActiveImplementation science communications2023
Irimu G, Okwaro F, Coleman J, et al.
Sleep, alcohol, and caffeine in financial traders.Other primary literatureHumanActivePloS one2023
Song F, Walker MP
Effects of caffeine consumption combined with listening to music during warm-up on taekwondo physical performance, perceived exertion and psychological aspects.Randomized controlled trialHumanActivePloS one2023
Delleli S, Ouergui I, Messaoudi H, et al.
Maternal tobacco, alcohol and caffeine consumption during the perinatal period: A prospective cohort study in Greece during the COVID-19 pandemic.Other primary literatureUnknownActiveTobacco induced diseases2023
Tigka M, Metallinou D, Tzeli M, et al.
Lack of Evidence for Blood Pressure Effects of Caffeine Added to Ibuprofen.Other primary literatureHumanActiveCurrent drug safety2023
Lampert A, Lange R, Weiser T
Caffeine intoxication as a result of excessive consumption of bottled coffee products: a case report.Other primary literatureUnknownActiveJournal of rural medicine : JRM2023
Ito M, Ando T, Yamamoto K, et al.
Maternal caffeine consumption during pregnancy and offspring cord blood DNA methylation: an epigenome-wide association study meta-analysis.Meta-analysisHumanActiveEpigenomics2023
Schellhas L, Monasso GS, Felix JF, et al.
The Use of Caffeine Citrate for Respiratory Stimulation in Acquired Central Hypoventilation Syndrome: A Case Series.Other primary literatureUnknownActiveJournal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)2023
Ling Tan P, Poh Lim C, Ong S, et al.
Caffeine addiction and determinants of caffeine consumption among health care providers: a descriptive national study.Other primary literatureHumanActiveEuropean review for medical and pharmacological sciences2023
Amer SA, AlAmri FA, AlRadini FA, et al.
P53 Gene Expression and Nitric Oxide Levels after Artemisinin-Caffeine Treatment in Breast, Lungs and Liver of DMBA-Induced Tumorigenesis.Other primary literatureAnimalActiveAsian Pacific journal of cancer prevention : APJCP2023
Dokunmu TM, Opara SC, Imaga NA, et al.
Correlation of effectiveness and tolerability assessments from a pharmacy-based observational study investigating the fixed-dose combination of 400 mg ibuprofen plus 100 mg caffeine for the treatment of acute headache.Other primary literatureUnknownActiveFrontiers in neurology2023
Gaul C, Förderreuther S, Lehmacher W, et al.
Comparison of effects of modafinil and caffeine on fatigue-vulnerable and fatigue-resistant aircrew after a limited period of sleep deprivation.Other primary literatureUnknownActiveFrontiers in physiology2023
Wingelaar-Jagt YQ, Wingelaar TT, Riedel WJ, et al.
The biosynthesis of EGCG, theanine and caffeine in response to temperature is mediated by hormone signal transduction factors in tea plant (Camellia sinensis L.).Other primary literatureUnknownActiveFrontiers in plant science2023
Zhu Q, Liu L, Lu X, et al.
Paraxanthine safety and comparison to caffeine.Other primary literatureUnknownActiveFrontiers in toxicology2023
Szlapinski SK, Charrette A, Guthrie N, et al.
Cardiorespiratory and Neuroprotective Effects of Caffeine in Neonate Animal Models.ReviewUnknownActiveAnimals : an open access journal from MDPI2023
Mota-Rojas D, Villanueva-García D, Hernández-Ávalos I, et al.
Caffeine Administration in Piglets with Low Birthweight and Low Vitality Scores, and Its Effect on Physiological Blood Profile, Acid-Base Balance, Gas Exchange, and Infrared Thermal Response.Other primary literatureUnknownActiveAnimals : an open access journal from MDPI2023
Villanueva-García D, Ghezzi M, Mora-Medina P, et al.
Protective Effects of Early Caffeine Administration in Hyperoxia-Induced Neurotoxicity in the Juvenile Rat.Other primary literatureUnknownActiveAntioxidants (Basel, Switzerland)2023
Heise J, Schmitz T, Bührer C, et al.
Vitamin B12 Supplementation Improves Oocyte Development by Modulating Mitochondria and Yolk Protein in a Caffeine-Ingested Caenorhabditis elegans Model.Other primary literatureUnknownActiveAntioxidants (Basel, Switzerland)2023
Min H, Lee M, Kang S, et al.
Single Mutations in Cytochrome P450 Oxidoreductase Can Alter the Specificity of Human Cytochrome P450 1A2-Mediated Caffeine Metabolism.Other primary literatureHumanActiveBiomolecules2023
Esteves F, Almeida CMM, Silva S, et al.
Effects of Caffeine on Main Symptoms in Children with ADHD: A Systematic Review and Meta-Analysis of Randomized Trials.ReviewUnknownActiveBrain sciences2023
Perrotte G, Moreira MMG, de Vargas Junior A, et al.
Caffeine Administration Mitigates Chronic Stress-Induced Behavioral Deficits, Neurochemical Alterations, and Glial Disruptions in Rats.Other primary literatureUnknownActiveBrain sciences2023
Okeowo OM, Oke OO, David GO, et al.
A Combination of Taurine and Caffeine in Stallion Semen Extender Positively Affects the Spermatozoa Parameters.Other primary literatureAnimalActiveCells2023
Halo M Jr, Tirpák F, Slanina T, et al.
Environmental and Yield Comparison of Quick Extraction Methods for Caffeine and Chlorogenic Acid from Spent Coffee Grounds.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2023
Bouhzam I, Cantero R, Balcells M, et al.
Caffeine Synthesis and Its Mechanism and Application by Microbial Degradation, A Review.ReviewUnknownActiveFoods (Basel, Switzerland)2023
Lin Z, Wei J, Hu Y, et al.
Antifibrotic Effects of Caffeine, Curcumin and Pirfenidone in Primary Human Keratocytes.Other primary literatureHumanActiveInternational journal of molecular sciences2023
Talpan D, Salla S, Seidelmann N, et al.
Optimization of the Zebrafish Larvae Pentylenetetrazol-Induced Seizure Model for the Study of Caffeine and Topiramate Interactions.Other primary literatureAnimalActiveInternational journal of molecular sciences2023
Bartoszek A, Trzpil A, Kozub A, et al.
Synergistic Effect of Saccharin and Caffeine on Antiproliferative Activity in Human Ovarian Carcinoma Ovcar-3 Cells.Other primary literatureHumanActiveInternational journal of molecular sciences2023
Lee SJ, Park SY, Bak S, et al.
Paclitaxel and Caffeine-Taurine, New Colchicine Alternatives for Chromosomes Doubling in Maize Haploid Breeding.Other primary literatureHumanActiveInternational journal of molecular sciences2023
Arshad S, Wei M, Ali Q, et al.
Characteristics of Chitosan Films with the Bioactive Substances-Caffeine and Propolis.Other primary literatureUnknownActiveJournal of functional biomaterials2023
Stefanowska K, Woźniak M, Sip A, et al.
Natural Rubber/Hexagonal Mesoporous Silica Nanocomposites as Efficient Adsorbents for the Selective Adsorption of (-)-Epigallocatechin Gallate and Caffeine from Green Tea.Other primary literatureUnknownActiveMolecules (Basel, Switzerland)2023
Jermjun K, Khumho R, Thongoiam M, et al.
Secondary School Students and Caffeine: Consumption Habits, Motivations, and Experiences.Other primary literatureHumanActiveNutrients2023
Turner S, Ali A, Wham C, et al.
Effects of Chronic Administration of Green Tea Ethanol Extract on Sleep Architecture in Mice: A Comparative Study with a Representative Stimulant Caffeine.Other primary literatureAnimalActiveNutrients2023
Kim D, Kim S, Yoon M, et al.
Use of Caffeine-Containing Energy Drinks by Japanese Middle School Students: A Cross-Sectional Study of Related Factors.Other primary literatureHumanActiveNutrients2023
Yamasaki S, Kawasaki H, Cui Z
Gender Differences in the Frequency of Positive and Negative Effects after Acute Caffeine Consumption.Other primary literatureHumanActiveNutrients2023
Domaszewski P
The Association between Caffeine Intake and the Colonic Mucosa-Associated Gut Microbiota in Humans-A Preliminary Investigation.Other primary literatureHumanActiveNutrients2023
Dai A, Hoffman K, Xu AA, et al.
Tea Consumption and New-Onset Acute Kidney Injury: The Effects of Milk or Sweeteners Addition and Caffeine/Coffee.Other primary literatureHuman & animalActiveNutrients2023
Liu M, Yang S, Ye Z, et al.
Caffeine for Headaches: Helpful or Harmful? A Brief Review of the Literature.ReviewHumanActiveNutrients2023
Zduńska A, Cegielska J, Zduński S, et al.
Sex Related Differences in the Complex Relationship between Coffee, Caffeine and Atrial Fibrillation.ReviewHumanActiveNutrients2023
Coppi F, Bucciarelli V, Sinigaglia G, et al.
Caffeine Intake, Plasma Caffeine Level, and Kidney Function: A Mendelian Randomization Study.Other primary literatureHumanActiveNutrients2023
Giontella A, de La Harpe R, Cronje HT, et al.
Extrapolating the Coffee and Caffeine (1,3,7-Trimethylxanthine) Effects on Exercise and Metabolism-A Concise Review.ReviewHumanActiveNutrients2023
Starling-Soares B, Pereira M, Renke G
The Association between Caffeine Consumption from Coffee and Tea and Sleep Health in Male and Female Older Adults: A Cross-Sectional Study.Other primary literatureHumanActiveNutrients2023
van der Linden M, Olthof MR, Wijnhoven HAH
Synergistic Effects of Caffeine in Combination with Conventional Drugs: Perspectives of a Drug That Never Ages.ReviewUnknownActivePharmaceuticals (Basel, Switzerland)2023
Ialongo D, Tudino V, Arpacioglu M, et al.
Overview of Caffeine Effects on Human Health and Emerging Delivery Strategies.ReviewUnknownActivePharmaceuticals (Basel, Switzerland)2023
Saraiva SM, Jacinto TA, Jacinto TA, et al.
In Silico, In Vitro, and In Vivo Evaluation of Caffeine-Coated Nanoparticles as a Promising Therapeutic Avenue for AML through NF-Kappa B and TRAIL Pathways Modulation.Other primary literatureUnknownActivePharmaceuticals (Basel, Switzerland)2023
Siddique MH, Bukhari S, Khan IU, et al.
Comparing Salivary Caffeine Kinetics of 13C and 12C Caffeine for Gastric Emptying of 50 mL Water.Other primary literatureUnknownActivePharmaceutics2023
Grimm M, Rump A, Meilicke L, et al.
Caffeine Release from Magneto-Responsive Hydrogels Controlled by External Magnetic Field and Calcium Ions and Its Effect on the Viability of Neuronal Cells.Other primary literatureUnknownActivePolymers2023
Frachini ECG, Selva JSG, Falcoswki PC, et al.
Ecotoxicity of Caffeine as a Bio-Protective Component of Flax-Fiber-Reinforced Epoxy-Composite Building Material.Other primary literatureUnknownActivePolymers2023
Kobetičová K, Nábělková J, Brejcha V, et al.
Electrochemical Sensing Platform Based on Carbon Dots for the Simultaneous Determination of Theophylline and Caffeine in Tea.Other primary literatureUnknownActiveSensors (Basel, Switzerland)2023
Di Matteo P, Trani A, Bortolami M, et al.
Successful Use of Continuous Veno-Venous Haemodialysis in a Case of Potential Lethal Caffeine Intoxication.Other primary literatureUnknownActiveToxics2023
Reimerink EJ, Huntjens DW, Pelkmans LG, et al.
The Impacts of the Multispecies Approach to Caffeine on Marine Invertebrates.Other primary literatureUnknownActiveToxics2023
Baracchini C, Messager L, Stocker P, et al.
Psychosis following caffeine consumption in a young adolescent: Review of case and literature.ReviewHumanActiveAnnals of African medicine2023
Adeleye QA, Attama CM, Egbeobauwaye O, et al.
Caffeine in Skincare: Its Role in Skin Cancer, Sun Protection, and Cosmetics.Other primary literatureUnknownActiveIndian journal of dermatology2023
Elias ML, Israeli AF, Madan R
Caffeine - Essentials for anaesthesiologists: A narrative review.ReviewUnknownActiveJournal of anaesthesiology, clinical pharmacology2023
Malviya AK, Saranlal AM, Mulchandani M, et al.
Effect of 3 and 6 mg/kg of caffeine on fat oxidation during exercise in healthy active females.Other primary literatureUnknownActiveBiology of sport2023
Varillas-Delgado D, Aguilar-Navarro M, Muñoz A, et al.
Does caffeine have a double-edged sword role in inflammation and carcinogenesis in the colon?ReviewUnknownActiveIntestinal research2023
Mizoguchi E, Sadanaga T, Okada T, et al.
Caffeine Consumption and Its Potential Health Effects on Saudi Adolescents in Jazan.Other primary literatureUnknownActiveCureus2023
Eltyeb EE, Al-Makramani AA, Mustafa MM, et al.
Caffeine Consumption and Depression, Anxiety, and Stress Levels Among University Students in Medina: A Cross-Sectional Study.Other primary literatureUnknownActiveCureus2023
Makki NM, Alharbi ST, Alharbi AM, et al.
Maternal Caffeine Consumption and Its Impact on the Fetus: A Review.ReviewUnknownActiveCureus2023
Lakin H, Sheehan P, Soti V
Fiberglass cloth coated by coffee ground waste-derived carbon quantum dots/titanium dioxide composite for removal of caffeine and other pharmaceuticals from waterOther primary literatureUnknownUnknownHeliyon2023
Muangmora R, Kemacheevakul P, Chuangchote S
Caffeine Consumption and Dementia: Are Lewy Bodies the Link?Other primary literatureHumanActiveAnnals of neurology2022
Cornelis MC, Bennett DA, Weintraub S, et al.
Therapeutic drug monitoring of caffeine and its primary metabolites in plasma using LC-ESI-MS/MS for apnea of prematurity treatment: Evaluation of ultrapure water as a surrogate matrix.Other primary literatureHuman & animalActiveBiomedical chromatography : BMC2022
Long JY, Hu YH, Xia Y, et al.
Caffeine content of energy drinks marketed in Brazil.Other primary literatureHumanActiveDrug testing and analysis2022
da Costa BRB, El Haddad LP, De Martinis BS
Caffeine-induced neurotoxicity mediated by Nrf2 pathway in PC12 cells and zebrafish larvae.Other primary literatureAnimalActiveJournal of applied toxicology : JAT2022
Chian S, Jiang ZC, Jiang LX, et al.
The upregulation of glutamate decarboxylase 67 against hippocampal excitability damage in male fetal rats by prenatal caffeine exposure.Other primary literatureAnimalActiveEnvironmental toxicology2022
Lu M, He X, Jiao Z, et al.
The effects of caffeine on bone mineral density and fracture risk.Other primary literatureHumanActiveOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2022
Berman NK, Honig S, Cronstein BN, et al.
Evaluation of a six-probe cocktail (caffeine, tolbutamide, omeprazole, dextromethorphan, midazolam, and digoxin) approach to estimate hepatic drug detoxification capability and dosage requirements after a single oral dosing in healthy Chinese volunteers.Other primary literatureHumanActiveNaunyn-Schmiedeberg's archives of pharmacology2022
Koo SH, Soon GH, Pruvost A, et al.
Risk or benefit? Side effects of caffeine supplementation in sport: a systematic review.Systematic reviewHumanActiveEuropean journal of nutrition2022
de Souza JG, Del Coso J, Fonseca FS, et al.
Effect of caffeine on muscle oxygen saturation during short-term all-out exercise: a double-blind randomized crossover study.Randomized controlled trialHumanActiveEuropean journal of nutrition2022
Ruiz-Moreno C, Gutiérrez-Hellín J, Lara B, et al.
Does caffeine consumption affect laparoscopic skills in a motion tracking analysis? A prospective, randomized, blinded crossover trial.Randomized controlled trialHumanActiveSurgical endoscopy2022
von Bechtolsheim F, Oehme F, Maruschke M, et al.
Modeling studies on the role of vitamins B1 (thiamin), B3 (nicotinamide), B6 (pyridoxamine), and caffeine as potential leads for the drug design against COVID-19.Other primary literatureHumanActiveJournal of molecular modeling2022
Aghamohammadi M, Sirouspour M, Goncalves AS, et al.
Caffeine and Its Neuroprotective Role in Ischemic Events: A Mechanism Dependent on Adenosine Receptors.ReviewHumanActiveCellular and molecular neurobiology2022
Pereira-Figueiredo D, Nascimento AA, Cunha-Rodrigues MC, et al.
Effectiveness and safety of early versus late caffeine therapy in managing apnoea of prematurity among preterm infants: a retrospective cohort study.Other primary literatureHumanActiveInternational journal of clinical pharmacy2022
Yun WZ, Kassab YW, Yao LM, et al.
Investigation of potential behavioral and physiological effects of caffeine on D. magna.Other primary literatureAnimalActiveEnvironmental science and pollution research international2022
Nunes B, Santos J, Dionísio R, et al.
Environmentally relevant concentration of caffeine-effect on activity and circadian rhythm in wild perch.Other primary literatureAnimalActiveEnvironmental science and pollution research international2022
Cerveny D, Cisar P, Brodin T, et al.
Association of caffeine and caffeine metabolites with obesity among children and adolescents: National Health and Nutrition Examination Survey (NHANES) 2009-2014.Other primary literatureHumanActiveEnvironmental science and pollution research international2022
Yu L, Mei H, Shi D, et al.
The Inverted U-Shaped Association of Caffeine Intake with Serum Uric Acid in U.S. Adults.Other primary literatureHumanActiveThe journal of nutrition, health & aging2022
Liu A, Jiang C, Liu Q, et al.
Mental Performance and Sport: Caffeine and Co-consumed Bioactive Ingredients.ReviewHumanActiveSports medicine (Auckland, N.Z.)2022
Kennedy DO, Wightman EL
A successful experience using labetalol and hemodialysis to treat near-fatal caffeine poisoning: A case report with toxicodynamics.Other primary literatureHumanActiveThe American journal of emergency medicine2022
Ou HC, Deng JF, Yang CC, et al.
Assessment of caffeine neurotoxicity using novel biomarkers of neural function in SH-SY5Y cells - Is there a need for environmental concern?Other primary literatureHumanActiveChemico-biological interactions2022
Vulin I, Tenji D, Teodorovic I, et al.
Caffeine as a contaminant of concern: A review on concentrations and impacts in marine coastal systems.ReviewHuman & animalActiveChemosphere2022
Vieira LR, Soares AMVM, Freitas R
Will extreme weather events influence the toxic impacts of caffeine in coastal systems? Comparison between two widely used bioindicator species.Other primary literatureHuman & animalActiveChemosphere2022
De Marchi L, Vieira LR, Intorre L, et al.
Mechanistic insights into UV photolysis of carbamazepine and caffeine: Active species, reaction sites, and toxicity evolution.Other primary literatureHumanActiveChemosphere2022
Liu H, Meng Y, Li J, et al.
Ecdysteroid kinase-like (EcKL) paralogs confer developmental tolerance to caffeine in Drosophila melanogaster.Other primary literatureUnknownActiveCurrent research in insect science2022
Scanlan JL, Battlay P, Robin C
Neurotoxic, biotransformation, oxidative stress and genotoxic effects in Astyanax altiparanae (Teleostei, Characiformes) males exposed to environmentally relevant concentrations of diclofenac and/or caffeine.Other primary literatureAnimalActiveEnvironmental toxicology and pharmacology2022
Muñoz-Peñuela M, Moreira RG, Gomes ADO, et al.
Prenatal caffeine exposure induced renal developmental toxicity and transgenerational effect in rat offspring.Other primary literatureHuman & animalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2022
Zhao X, Li B, Xiong Y, et al.
Caffeine intoxication: Behavioral and electrocorticographic patterns in Wistar rats.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2022
Azevedo JEC, da Silva ALM, Vieira LR, et al.
A case of refractory ventricular fibrillation after caffeine poisoning successfully treated by supportive care.Other primary literatureUnknownActiveToxicology reports2022
Han K, You KM, Jung JH
A Sulfonated Tweezer-Shaped Receptor Selectively Recognizes Caffeine in Water.Other primary literatureUnknownActiveThe Journal of organic chemistry2022
Francesconi O, Ienco A, Papi F, et al.
Caffeine Enhances the Toxicity of Platinum-Based Drugs at the Molecular Level Even Outside of the Intracellular Environment: A Single-Molecule Force Spectroscopy Study.Other primary literatureUnknownActiveThe journal of physical chemistry. B2022
de Oliveira RM, Moura TA, Rocha MS
Caffeine Encapsulation in Metal Organic Framework MIL-53(Al) at Pilot Plant Scale for Preparation of Polyamide Textile Fibers with Cosmetic Properties.Other primary literatureUnknownActiveACS applied materials & interfaces2022
Zornoza B, Rubio C, Piera E, et al.
Design of an Efficient Tin Selenide-Based Ternary Nanocomposite Electrode for Simultaneous Determination of Paracetamol, Tryptophan, and Caffeine.Other primary literatureUnknownActiveACS omega2022
Eagambaram M, Kumar K
Five-year outcomes of premature infants randomized to high or standard loading dose caffeine.Randomized controlled trialHumanActiveJournal of perinatology : official journal of the California Perinatal Association2022
McPherson C, Lean RE, Cyr PEP, et al.
Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance.Other primary literatureHuman & animalActiveNature communications2022
Lebeau PF, Byun JH, Platko K, et al.
Anti-biofilm activity of caffeine against uropathogenic E. coli is mediated by curli biogenesis.Other primary literatureUnknownActiveScientific reports2022
Rathi B, Gupta S, Kumar P, et al.
Mechanism and behavior of caffeine sorption: affecting factors.ReviewUnknownActiveRSC advances2022
Fakioğlu M, Kalpaklı Y
Urinary caffeine and caffeine metabolites, asthma, and lung function in a nationwide study of U.S. adults.Other primary literatureHumanActiveThe Journal of asthma : official journal of the Association for the Care of Asthma2022
Han YY ,, Forno E, Celedón JC
Effects of caffeine, methylliberine, and theacrine on vigilance, marksmanship, and hemodynamic responses in tactical personnel: a double-blind, randomized, placebo-controlled trial.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2022
Cintineo HP, Bello ML, Chandler AJ, et al.
Caffeine Enhances Intermittent Hypoxia-Induced Gains in Walking Function for People with Chronic Spinal Cord Injury.Randomized controlled trialHumanActiveJournal of neurotrauma2022
Trumbower RD, Barth S, Tuthill C, et al.
Maternal caffeine intake and DNA methylation in newborn cord blood.Other primary literatureHumanActiveThe American journal of clinical nutrition2022
Polinski KJ, Purdue-Smithe A, Robinson SL, et al.
Is it caffeine? Coffee consumption and future risk of type 2 diabetes among women with a history of gestational diabetes.Other primary literatureHumanActiveThe American journal of clinical nutrition2022
Chen LW
A novel TcS allele conferring the high-theacrine and low-caffeine traits and having potential use in tea plant breeding.Other primary literatureUnknownActiveHorticulture research2022
Zhong H, Wang Y, Qu FR, et al.
Development and Validation of Ultra Performance Liquid Chromatography (UPLC) Method for the Quantitative Estimation of Caffeine in Non-Alcoholic Soft and Energy Drinks.Other primary literatureHumanActiveJournal of AOAC International2022
Ahmad W, Yusuf M, Ahmad A, et al.
Assessment of caffeine consumption behavior among Jazan University students in the south of Saudi Arabia: A cross-sectional study.Other primary literatureHumanActiveMedicine2022
Alfaifi MH, Gosadi IM, Alfaifi SM, et al.
Nicotinamide riboside and caffeine partially restore diminished NAD availability but not altered energy metabolism in Alzheimer's disease.Other primary literatureHumanActiveAging cell2022
Ryu WI, Shen M, Lee Y, et al.
Fluted pumpkin seeds protect the spermatogenesis score index and testicular histology of caffeine treated rats.Other primary literatureAnimalActiveAndrologia2022
Ezim OE, Abarikwu SO
The association between caffeine and alcohol consumption and IVF/ICSI outcomes: A systematic review and dose-response meta-analysis.Meta-analysisHumanActiveActa obstetricia et gynecologica Scandinavica2022
Rao W, Li Y, Li N, et al.
Adenosine A<sub>2A</sub> receptor antagonists: from caffeine to selective non-xanthines.ReviewUnknownActiveBritish journal of pharmacology2022
Jacobson KA, Gao ZG, Matricon P, et al.
Proteomic analysis of the effects of caffeine in a neonatal rat model of hypoxic-ischemic white matter damage.Other primary literatureHuman & animalActiveCNS neuroscience & therapeutics2022
Yang L, Yu X, Zhang Y, et al.
Evaluation of CYP1A2 activity: Relationship between the endogenous urinary 6-hydroxymelatonin to melatonin ratio and paraxanthine to caffeine ratio in dried blood spots.Other primary literatureHumanActiveClinical and translational science2022
Magliocco G, Desmeules J, Samer CF, et al.
Aspirin, paracetamol (acetaminophen) and caffeine for the treatment of acute migraine attacks: A systemic review and meta-analysis of randomized placebo-controlled trials.Meta-analysisHumanActiveEuropean journal of neurology2022
Diener HC, Gaul C, Lehmacher W, et al.
Cardiovascular risk of energy drinks: Caffeine and taurine facilitate ventricular arrhythmias in a sensitive whole-heart model.Other primary literatureHuman & animalActiveJournal of cardiovascular electrophysiology2022
Ellermann C, Hakenes T, Wolfes J, et al.
Prenatal caffeine exposure: association with neurodevelopmental outcomes in 9- to 11-year-old children.Other primary literatureHumanActiveJournal of child psychology and psychiatry, and allied disciplines2022
Zhang R, Manza P, Volkow ND
The association between caffeine exposure during pregnancy and risk of gestational hypertension/preeclampsia: A meta-analysis and systematical review.Meta-analysisHumanActiveThe journal of obstetrics and gynaecology research2022
Chen B, Zhang M, He Y, et al.
Impacts of caffeine on resistant chicken's performance and cardiovascular gene expression.Other primary literatureAnimalActiveJournal of animal physiology and animal nutrition2022
Kamely M, Karimi Torshizi MA, West J, et al.
Adenosine, caffeine, and sleep-wake regulation: state of the science and perspectives.ReviewHumanActiveJournal of sleep research2022
Reichert CF, Deboer T, Landolt HP
Direct Uptake of Nutrition and Caffeine Study (DUNCS): biscuit based comparative study.Other primary literatureAnimalActiveBMJ (Clinical research ed.)2022
Jones C, Francis J
Effects of Caffeine Intake on Cardiopulmonary Variables and QT Interval after a Moderate-Intensity Aerobic Exercise in Healthy Adults: A Randomized Controlled Trial.Randomized controlled trialHumanRetractedBioMed research international2022
Yu J, Lim JH, Seo SW, et al.
Caffeine Consumption among Various University Students in the UAE, Exploring the Frequencies, Different Sources and Reporting Adverse Effects and Withdrawal Symptoms.Other primary literatureUnknownActiveJournal of nutrition and metabolism2022
Kharaba Z, Sammani N, Ashour S, et al.
The Conflicting Role of Caffeine Supplementation on Hyperoxia-Induced Injury on the Cerebellar Granular Cell Neurogenesis of Newborn Rats.Other primary literatureHuman & animalActiveOxidative medicine and cellular longevity2022
Giszas V, Strauß E, Bührer C, et al.
Effect of Caffeine Injection on Orthodontic Tooth Movement in Rats: An Experimental Study on Rats.Other primary literatureUnknownActiveInternational journal of dentistry2022
Golshah A, Omidi K, Nikkerdar N, et al.
Is Early Preventive Caffeine Safe and Effective in Premature Neonates? A Clinical Trial.Other primary literatureUnknownActiveInternational journal of pediatrics2022
Sajjadian N, Taheri PA, Jabbari M
Caffeine: Some of the Evidence behind Its Use and Abuse in the Preterm Infant.ReviewHumanActiveNeonatology2022
Chavez L, Bancalari E
The impacts of caffeine administration, expectancies, and related stimuli on coffee craving, withdrawal, and self-administration.Other primary literatureHumanActiveJournal of psychopharmacology (Oxford, England)2022
Shephard A, Barrett SP
EEG Microstates in Early Phase Psychosis: The Effects of Acute Caffeine Consumption.Randomized controlled trialHumanActiveClinical EEG and neuroscience2022
N Bissonnette J, Anderson TJ, McKearney KJ, et al.
Effects of Caffeine on Intervertebral Disc Cell Viability in a Whole Organ Culture Model.Other primary literatureUnknownActiveGlobal spine journal2022
Raines BT, Stannard JT, Stricklin OE, et al.
Relationship of caffeine regimen with osteopenia of prematurity in preterm neonates: a cohort retrospective study.Other primary literatureHumanActiveBMC pediatrics2022
Kumar M, Ali A, Khan MA, et al.
Mitigative effect of caffeine against diclofenac-induced hepato-renal damage and chromosomal aberrations in male albino rats.Other primary literatureAnimalActiveBMC complementary medicine and therapies2022
Anwar MM, Laila IMI
Prevalence of caffeine consumers, daily caffeine consumption, and factors associated with caffeine use among active duty United States military personnel.Other primary literatureHumanActiveNutrition journal2022
Knapik JJ, Steelman RA, Trone DW, et al.
The association between caffeine intake and testosterone: NHANES 2013-2014.Other primary literatureHumanActiveNutrition journal2022
Glover FE, Caudle WM, Del Giudice F, et al.
Comparative efficacy and safety of caffeine citrate and aminophylline in treating apnea of prematurity: A systematic review and meta-analysis.Meta-analysisHumanActivePloS one2022
Miao Y, Zhou Y, Zhao S, et al.
Evaluation of pharmaceutically compounded oral caffeine on the impact of medication adherence and risk of readmission among preterm neonates: A single-center quasi-experimental study.Other primary literatureHumanActivePloS one2022
Ambreen G, Kumar M, Ali A, et al.
In silico studies of natural product-like caffeine derivatives as potential MAO-B inhibitors/AA2AR antagonists for the treatment of Parkinson's disease.Other primary literatureHumanActiveJournal of integrative bioinformatics2022
Boulaamane Y, Ibrahim MAA, Britel MR, et al.
The effects of caffeine on the motility and viability of stallion spermatozoa at different temperature conditions.Other primary literatureUnknownActiveActa veterinaria Hungarica2022
Halo M Jr, Tirpák F, Massányi M, et al.
Role of Caffeine in the Age-related Neurodegenerative Diseases: A Review.ReviewHumanActiveMini reviews in medicinal chemistry2022
Pohanka M
Nasal Caffeine Thermo-Sensitive In Situ Gel for Enhanced Cognition after Sleep-Deprivation.Other primary literatureAnimalActiveCurrent drug delivery2022
Zhu S, Zhang Y, Li Q, et al.
Neurochemical and Behavioral Consequences of Ethanol and/or Caffeine Exposure: Effects in Zebrafish and Rodents.ReviewAnimalActiveCurrent neuropharmacology2022
Clayman CL, Connaughton VP
Treatment of Lethal Caffeine Overdose with Haemodialysis: A Case Report and Review.Other primary literatureUnknownActiveJournal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures)2022
Gahona CCT, Bharadwaj AK, Shah M, et al.
A study on acute oral caffeine intoxication and its treatment strategies in domestic pigeons (Columba livia domestica).Other primary literatureUnknownActiveVeterinary research forum : an international quarterly journal2022
Sedghi S, Mosleh N, Shomali T, et al.
Effect of Caffeine on the Acceleration of Emergence from General Anesthesia with Inhalation Anesthetics in Children Undergoing Inguinal Herniorrhaphy: A Randomized Clinical Trial.Randomized controlled trialHumanActiveIranian journal of medical sciences2022
Emami S, Panah A, Hakimi SS, et al.
Caffeine Restores Neuronal Damage and Inflammatory Response in a Model of Intraventricular Hemorrhage of the Preterm Newborn.Other primary literatureUnknownActiveFrontiers in cell and developmental biology2022
Alves-Martinez P, Atienza-Navarro I, Vargas-Soria M, et al.
Yap1-mediated Flr1 expression reveals crosstalk between oxidative stress signaling and caffeine resistance in Saccharomyces cerevisiae.Other primary literatureUnknownActiveFrontiers in microbiology2022
Choi JE, Heo SH, Chung WH
Caffeine Attenuates Electroacupuncture Effect on Pressure Pain Threshold and Tolerance in Healthy Individuals: A Randomized Controlled Trial.Other primary literatureUnknownActiveFrontiers in neurology2022
Liu K, Cui X, Zhi M, et al.
Association of caffeine intake with all-cause and cardiovascular mortality in elderly patients with hypertension.Other primary literatureUnknownActiveFrontiers in nutrition2022
Chen S, Li J, Gao M, et al.
Urate oxidase from tea microbe Colletotrichum camelliae is involved in the caffeine metabolism pathway and plays a role in fungal virulence.Other primary literatureUnknownActiveFrontiers in nutrition2022
He S, Qiao X, Zhang S, et al.
Association of Coffee, Tea, and Caffeine Consumption With All-Cause Risk and Specific Mortality for Cardiovascular Disease Patients.Other primary literatureUnknownActiveFrontiers in nutrition2022
Zheng H, Lin F, Xin N, et al.
Relationship between maternal caffeine and coffee intake and pregnancy loss: A grading of recommendations assessment, development, and evaluation-assessed, dose-response meta-analysis of observational studies.Systematic reviewUnknownActiveFrontiers in nutrition2022
Jafari A, Naghshi S, Shahinfar H, et al.
Sucrose dampens caffeine-induced blood pressure elevations - A randomized crossover pilot study in healthy, non-obese men.Other primary literatureUnknownActiveFrontiers in nutrition2022
Ravussin Y, Montani JP, Grasser EK
Caffeine consumption within British fencing athletes.Other primary literatureUnknownActiveFrontiers in nutrition2022
Morris GB, Manders RJF, Hulton AT
Specific Premature Groups Have Better Benefits When Treating Apnea With Caffeine Than Aminophylline/Theophylline.Other primary literatureUnknownActiveFrontiers in pediatrics2022
Lin YC, Tan YL, Yen TA, et al.
Molecular Mechanism of Caffeine in Preventing Bronchopulmonary Dysplasia in Premature Infants.ReviewUnknownActiveFrontiers in pediatrics2022
Tian C, Li D, Fu J
Caffeine in liver diseases: Pharmacology and toxicology.ReviewUnknownActiveFrontiers in pharmacology2022
Shan L, Wang F, Zhai D, et al.
Precision caffeine therapy for apnea of prematurity and circadian rhythms: New possibilities open up.ReviewUnknownActiveFrontiers in pharmacology2022
Dai HR, Guo HL, Hu YH, et al.
Both caffeine and Capsicum annuum fruit powder lower blood glucose levels and increase brown adipose tissue temperature in healthy adult males.Other primary literatureUnknownCorrectedFrontiers in physiology2022
Van Schaik L, Kettle C, Green R, et al.
Functional identification of purine permeases reveals their roles in caffeine transport in tea plants (Camellia sinensis).Other primary literatureUnknownActiveFrontiers in plant science2022
Zhang Y, Wei K, Guo L, et al.
Caffeine Supplementation Strategies Among Endurance Athletes.Other primary literatureUnknownActiveFrontiers in sports and active living2022
Kreutzer A, Graybeal AJ, Moss K, et al.
Cryopreservation of Sperm from an Endangered Snake with Tests of Post-Thaw Incubation in Caffeine.Other primary literatureUnknownActiveAnimals : an open access journal from MDPI2022
Sandfoss MR, Cantrell J, Roberts BM, et al.
Validation of Psychophysiological Measures for Caffeine Oral Films Characterization by Machine Learning Approaches.Other primary literatureUnknownActiveBioengineering (Basel, Switzerland)2022
Batista P, Rodrigues PM, Ferreira M, et al.
Does Caffeine Supplementation Associated with Paralympic Powerlifting Training Interfere with Hemodynamic Indicators?Other primary literatureUnknownActiveBiology2022
Menezes JL, Aidar FJ, Badicu G, et al.
An Exploratory Study about the Characterization of Caffeine Consumption in a Portuguese Sample.Other primary literatureUnknownActiveBehavioral sciences (Basel, Switzerland)2022
Batista P, Peixoto J, Oliveira-Silva P
Risk Assessment of Caffeine and Epigallocatechin Gallate in Coffee Leaf Tea.ReviewUnknownActiveFoods (Basel, Switzerland)2022
Tritsch N, Steger MC, Segatz V, et al.
Intake of Food Supplements, Caffeine, Green Tea and Protein Products among Young Danish Men Training in Commercial Gyms for Increasing Muscle Mass.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2022
Pilegaard K, Uldall ASM, Ravn-Haren G
The Impact of Lockdowns on Caffeine Consumption: A Systematic Review of the Evidence.Systematic reviewHumanActiveInternational journal of environmental research and public health2022
Bakaloudi DR, Evripidou K, Jayawardena R, et al.
In Utero Exposure to Caffeine and Acetaminophen, the Gut Microbiome, and Neurodevelopmental Outcomes: A Prospective Birth Cohort Study.Other primary literatureHumanActiveInternational journal of environmental research and public health2022
Laue HE, Shen Y, Bloomquist TR, et al.
Central Nervous System Stimulants Limit Caffeine Transport at the Blood-Cerebrospinal Fluid Barrier.Other primary literatureHumanActiveInternational journal of molecular sciences2022
Ikeda-Murakami K, Tani N, Ikeda T, et al.
Caffeine and MDMA (Ecstasy) Exacerbate ER Stress Triggered by Hyperthermia.Other primary literatureHuman & animalActiveInternational journal of molecular sciences2022
Trychta KA, Harvey BK
Quantification of Caffeine Interactions in Choline Chloride Natural Deep Eutectic Solvents: Solubility Measurements and COSMO-RS-DARE Interpretation.Other primary literatureUnknownActiveInternational journal of molecular sciences2022
Jeliński T, Cysewski P
Caffeine Inhibits NLRP3 Inflammasome Activation by Downregulating TLR4/MAPK/NF-κB Signaling Pathway in an Experimental NASH Model.Other primary literatureAnimalActiveInternational journal of molecular sciences2022
Vargas-Pozada EE, Ramos-Tovar E, Rodriguez-Callejas JD, et al.
Neurodegenerative Diseases: Can Caffeine Be a Powerful Ally to Weaken Neuroinflammation?ReviewHumanActiveInternational journal of molecular sciences2022
Ruggiero M, Calvello R, Porro C, et al.
Caffeine and Its Antioxidant Properties-It Is All about Dose and Source.ReviewHumanActiveInternational journal of molecular sciences2022
Ősz BE, Jîtcă G, Ștefănescu RE, et al.
Caffeine-Induced Sleep Restriction Alters the Gut Microbiome and Fecal Metabolic Profiles in Mice.Other primary literatureAnimalActiveInternational journal of molecular sciences2022
Song Z, Liu L, Xu Y, et al.
Paternal Nicotine/Ethanol/Caffeine Mixed Exposure Induces Offspring Rat Dysplasia and Its Potential "GC-IGF1" Programming Mechanism.Meta-analysisAnimalActiveInternational journal of molecular sciences2022
Liu Y, Zhang C, Liu Y, et al.
Elevation of Anticancer Drug Toxicity by Caffeine in Spheroid Model of Human Lung Adenocarcinoma A549 Cells Mediated by Reduction in Claudin-2 and Nrf2 Expression.Other primary literatureHumanActiveInternational journal of molecular sciences2022
Eguchi H, Kimura R, Onuma S, et al.
Impact of Caffeine on Alzheimer's Disease Pathogenesis-Protective or Risk Factor?ReviewUnknownActiveLife (Basel, Switzerland)2022
Schreiner TG, Popescu BO
Therapeutic Interventions in Rat Models of Preterm Hypoxic Ischemic Injury: Effects of Hypothermia, Caffeine, and the Influence of Sex.ReviewUnknownActiveLife (Basel, Switzerland)2022
McLeod R, Rosenkrantz T, Fitch RH
Application of the Solute-Solvent Intermolecular Interactions as Indicator of Caffeine Solubility in Aqueous Binary Aprotic and Proton Acceptor Solvents: Measurements and Quantum Chemistry Computations.Other primary literatureUnknownActiveMaterials (Basel, Switzerland)2022
Jeliński T, Kubsik M, Cysewski P
A Green High-Performance Thin-Layer Chromatography Method for the Determination of Caffeine in Commercial Energy Drinks and Formulations.Other primary literatureUnknownActiveMaterials (Basel, Switzerland)2022
Foudah AI, Shakeel F, Salkini MA, et al.
Antioxidant and Sensory Assessment of Innovative Coffee Blends of Reduced Caffeine Content.Other primary literatureHumanActiveMolecules (Basel, Switzerland)2022
Šeremet D, Fabečić P, Vojvodić Cebin A, et al.
Acute Effects of Low Dose of Caffeine Ingestion Combined with Conditioning Activity on Psychological and Physical Performances of Male and Female Taekwondo Athletes.Randomized controlled trialHumanActiveNutrients2022
Ouergui I, Mahdi N, Delleli S, et al.
Caffeine Intake and Its Sex-Specific Association with General Anxiety: A Cross-Sectional Analysis among General Population Adults.Other primary literatureHumanActiveNutrients2022
Paz-Graniel I, Kose J, Babio N, et al.
Dysmetabolism and Sleep Fragmentation in Obstructive Sleep Apnea Patients Run Independently of High Caffeine Consumption.Other primary literatureHumanActiveNutrients2022
Conde SV, Martins FO, Dias SS, et al.
Total 25(OH)D Concentration Moderates the Association between Caffeine Consumption and the Alkaline Phosphatase Level in Pregnant Women.Other primary literatureHumanActiveNutrients2022
Tung KTS, Wong RS, Cheung CKM, et al.
Plasma Caffeine Levels and Risk of Alzheimer's Disease and Parkinson's Disease: Mendelian Randomization Study.Other primary literatureHumanActiveNutrients2022
Larsson SC, Woolf B, Gill D
Effect of Caffeine Ingestion on Indirect Markers of Exercise-Induced Muscle Damage: A Systematic Review of Human Trials.Systematic reviewHumanActiveNutrients2022
Caldas LC, Salgueiro RB, Clarke ND, et al.
Caffeine, Paraxanthine, Theophylline, and Theobromine Content in Human Milk.Other primary literatureHumanActiveNutrients2022
Purkiewicz A, Pietrzak-Fiećko R, Sörgel F, et al.
Effect of Black Pepper (Piper nigrum) Extract on Caffeine-Induced Sleep Disruption and Excitation in Mice.Other primary literatureAnimalActiveNutrients2022
Yoon M, Jung J, Kim M, et al.
The Matrix Matters: Beverage Carbonation Impacts the Timing of Caffeine Effects on Sustained Attention.Randomized controlled trialHumanActiveNutrients2022
De Longis E, Lerond C, Costello SE, et al.
Acute Effects of Caffeine Supplementation on Physical Performance, Physiological Responses, Perceived Exertion, and Technical-Tactical Skills in Combat Sports: A Systematic Review and Meta-Analysis.Meta-analysisUnknownActiveNutrients2022
Delleli S, Ouergui I, Messaoudi H, et al.
Can the Brazilian Caffeine Expectancy Questionnaires Differentiate the <i>CYP1A2</i> and <i>ADORA2A</i> Gene Polymorphisms?-An Exploratory Study with Brazilian Athletes.Other primary literatureHumanActiveNutrients2022
Mendes GF, Reis CEG, Nakano EY, et al.
Cardiometabolic Biomarkers and Habitual Caffeine Consumption Associate with the Adverse Ambulatory Blood Pressure Response to Strenuous Physical Exertion among Firefighters.Other primary literatureHumanActiveNutrients2022
Berkowsky RS, Zaleski AL, Taylor BA, et al.
Development of a Caffeine Content Table for Foods, Drinks, Medications and Supplements Typically Consumed by the Brazilian Population.ReviewUnknownActiveNutrients2022
Rocha PLA, Lima ALC, Saunders B, et al.
Prenatal Caffeine Exposure Is Linked to Elevated Sugar Intake and BMI, Altered Reward Sensitivity, and Aberrant Insular Thickness in Adolescents: An ABCD Investigation.Other primary literatureHumanActiveNutrients2022
Agarwal K, Manza P, Tejeda HA, et al.
Not Another Caffeine Effect on Sports Performance Study-Nothing New or More to Do?ReviewUnknownActiveNutrients2022
Tallis J, Guimaraes-Ferreira L, Clarke ND
Caffeine, D-glucuronolactone and Taurine Content in Energy Drinks: Exposure and Risk Assessment.Other primary literatureHumanActiveNutrients2022
Rubio C, Cámara M, Giner RM, et al.
Caffeine Intake throughout Pregnancy, and Factors Associated with Non-Compliance with Recommendations: A Cohort Study.Other primary literatureHumanActiveNutrients2022
Román-Gálvez MR, Martín-Peláez S, Hernández-Martínez L, et al.
Effects of Caffeine, a DNA Damage Response Inhibitor, on Papillomavirus Genome Replication.Other primary literatureUnknownActivePathogens (Basel, Switzerland)2022
Kanginakudru S, Gilson T, Jose L, et al.
The Role of the Adenosine System on Emotional and Cognitive Disturbances Induced by Ethanol Binge Drinking in the Immature Brain and the Beneficial Effects of Caffeine.ReviewUnknownActivePharmaceuticals (Basel, Switzerland)2022
Pinheiro BG, Luz DA, Cartágenes SC, et al.
Tailoring Chlorthalidone Aqueous Solubility by Cocrystallization: Stability and Dissolution Behavior of a Novel Chlorthalidone-Caffeine Cocrystal.Other primary literatureUnknownActivePharmaceutics2022
Rodríguez-Ruiz C, Montes-Tolentino P, Domínguez-Chávez JG, et al.
Recent Advances in Electrochemical Sensors for Caffeine Determination.ReviewUnknownActiveSensors (Basel, Switzerland)2022
Tasić ŽZ, Petrović Mihajlović MB, Simonović AT, et al.
Effects of Caffeine, Theophylline, and Aminophylline on Electroconvulsive Therapy: A Review of Evidence.ReviewUnknownActiveJournal of microscopy and ultrastructure2022
Althagafi A
The Effect of Sumatriptan, Theophylline, Pregabalin and Caffeine on Prevention of Headache Caused By Spinal Anaesthesia (PDPH): A Systematic Review.ReviewUnknownActiveJournal of the West African College of Surgeons2022
Amini N, Modir H, Omidvar S, et al.
Determination of caffeine, paraxanthine, theophylline and theobromine in premature infants by HILIC-MS/MS.Other primary literatureHumanActiveBioanalysis2022
Wen SY, Ma H, Chen XL, et al.
Caffeine supplementation improves physical performance without affecting fatigue level: a double-blind crossover study.Other primary literatureUnknownActiveBiology of sport2022
Campos Y, Lago-Rodríguez Á, San Juan AF, et al.
Effect of caffeine on genes expressions of developing retinas in the chick model.Other primary literatureUnknownActiveAnatomy & cell biology2022
Lekchaoum T, Buddawong A, Ahi S, et al.
Clinical effect of different maintenance doses of caffeine citrate in the treatment of preterm infants requiring assisted ventilation: a pilot multicenter study.Other primary literatureHumanActiveZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2022
Yang Y, Lu KY, Cheng R, et al.
Severe Rhabdomyolysis Due to Strenuous Exercise With a Potential Role of a High-Caffeine Energy Drink.Other primary literatureUnknownActiveCureus2022
Tinawi M
Caffeine Intoxication: Unregulated, Over-the-Counter Sale of Potentially Deadly Supplements.Other primary literatureUnknownActiveCureus2022
Pina Cabral J, Sousa DL, Carvalho C, et al.
Sugars, Alcohol, and Caffeine Intake From Drinks Among Outpatients With Mental Health Disorders in Greece: A Pilot Study.Other primary literatureUnknownActiveCureus2022
Apostolakopoulou XA, Kontopoulou L, Karpetas GE, et al.
Serotonin Syndrome Triggered by Overuse of Caffeine and Complicated With Neuroleptic Malignant Syndrome: A Case Report.Other primary literatureUnknownActiveCureus2022
Ohta R, Sano C
Caffeine: What Is Its Role in Pain Medicine?ReviewUnknownActiveCureus2022
Boppana SH, Peterson M, Du AL, et al.
Association Between Maternal Caffeine Consumption and Metabolism and Neonatal Anthropometry: A Secondary Analysis of the NICHD Fetal Growth Studies-Singletons.Other primary literatureHumanActiveJAMA network open2021
Gleason JL, Tekola-Ayele F, Sundaram R, et al.
Caffeine-Operated Synthetic Modules for Chemogenetic Control of Protein Activities by Life Style.Other primary literatureUnknownActiveAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021
Wang T, He L, Jing J, et al.
Caffeine poisoning successfully treated by venoarterial extracorporeal membrane oxygenation and emergency hemodialysis.Other primary literatureUnknownActiveAcute medicine & surgery2021
Yasuda S, Hisamura M, Hirano T, et al.
Could aspartame exacerbate caffeine effects on renal maturation in rat's offspring? A biochemical and histological study.Randomized controlled trialHuman & animalActiveBirth defects research2021
Fareed SA, Mostafa HE
A Phase 1 Open-Label, Fixed-Sequence Pharmacokinetic Drug Interaction Trial to Investigate the Effect of Cannabidiol on the CYP1A2 Probe Caffeine in Healthy Subjects.Other primary literatureHumanActiveClinical pharmacology in drug development2021
Thai C, Tayo B, Critchley D
Hydrogen-rich water and caffeine for alertness and brain metabolism in sleep-deprived habitual coffee drinkers.Other primary literatureUnknownActiveFood science & nutrition2021
Todorovic N, Zanini D, Stajer V, et al.
Caffeic acid and caffeine attenuate toxicity associated with malonic or methylmalonic acid exposure in Drosophila melanogaster.Other primary literatureAnimalActiveNaunyn-Schmiedeberg's archives of pharmacology2021
Portela JL, Bianchini MC, Roos DH, et al.
The effects of caffeine on ovarian tissue in rats.Other primary literatureAnimalActiveNaunyn-Schmiedeberg's archives of pharmacology2021
Yadegari Dehnavi M, Mirjalili A, Dortaj H, et al.
Cognitive enhancement effects of stimulants: a randomized controlled trial testing methylphenidate, modafinil, and caffeine.Randomized controlled trialHumanActivePsychopharmacology2021
Repantis D, Bovy L, Ohla K, et al.
Simultaneous administration of cocaine and caffeine dysregulates HCN and T-type channels.Other primary literatureAnimalActivePsychopharmacology2021
Rivero-Echeto MC, Perissinotti PP, González-Inchauspe C, et al.
Caffeine content in newborn hair correlates with maternal dietary intake.Other primary literatureHumanActiveEuropean journal of nutrition2021
Lehtonen A, Uusitalo L, Auriola S, et al.
Maternal caffeine intake during pregnancy and child neurodevelopment up to eight years of age-Results from the Norwegian Mother, Father and Child Cohort Study.Other primary literatureHumanActiveEuropean journal of nutrition2021
Berglundh S, Vollrath M, Brantsæter AL, et al.
Caffeine increases whole-body fat oxidation during 1 h of cycling at Fatmax.Randomized controlled trialHumanActiveEuropean journal of nutrition2021
Ruiz-Moreno C, Gutiérrez-Hellín J, Amaro-Gahete FJ, et al.
Caffeine use during pregnancy: prevalence of use and newborn consequences in a cohort of French pregnant women.Other primary literatureHumanActiveEuropean archives of psychiatry and clinical neuroscience2021
Lamy S, Houivet E, Benichou J, et al.
Does caffeine enhance bowel recovery after elective colorectal resection? A prospective double-blinded randomized clinical trial.Randomized controlled trialHumanActiveTechniques in coloproctology2021
Parnasa SY, Marom G, Bdolah-Abram T, et al.
The effects of caffeine in adults with neurogenic orthostatic hypotension: a systematic review.Systematic reviewHumanActiveClinical autonomic research : official journal of the Clinical Autonomic Research Society2021
Gibbon JR, Frith J
Interaction of pig manure-derived dissolved organic matter with soil affects sorption of sulfadiazine, caffeine and atenolol pharmaceuticals.Other primary literatureAnimalActiveEnvironmental geochemistry and health2021
Zhang W, Tang X, Thiele-Bruhn S
The Relationship Between Energy Drink Consumption, Caffeine Content, and Nutritional Knowledge Among College Students.Other primary literatureHumanActiveThe journal of primary prevention2021
Hardy R, Kliemann N, Dahlberg P, et al.
Validation of the Turkish Version of the Caffeine Use Disorder Questionnaire in an Adult Population.Other primary literatureUnknownActiveInternational journal of mental health and addiction2021
Kaya S, Bodur M, Esgin Mİ, et al.
Massive β1-Adrenergic Receptor Reaction Explains Irreversible Acute Arrhythmia in a Fatal Case of Acute Pure Caffeine Intoxication.Other primary literatureHumanActiveCardiovascular toxicology2021
Maiese A, La Russa R, Del Fante Z, et al.
Caffeine Consumption and Behavioral Symptoms in Nursing Home Residents: A Cross-Sectional Analysis.Other primary literatureHumanActiveThe journal of nutrition, health & aging2021
Kromhout MA, Rius Ottenheim N, Putter H, et al.
Effect of caffeine on alcohol drinking in mice.Other primary literatureAnimalActiveAlcohol (Fayetteville, N.Y.)2021
Haun HL, Olsen ACK, Koch KE, et al.
The importance of early use of beta blockers and gastric decontamination in caffeine overdose: A case report.Other primary literatureHumanActiveAustralian critical care : official journal of the Confederation of Australian Critical Care Nurses2021
Ajjampur K, Subramaniam A
24-Epibrassinolide modulates the neurodevelopmental outcomes of high caffeine exposure in zebrafish (Danio rerio) embryos.Other primary literatureAnimalActiveComparative biochemistry and physiology. Toxicology & pharmacology : CBP2021
Félix L, Lobato-Freitas C, Monteiro SM, et al.
Acute effects of energy drink on hemodynamic and electrophysiologic parameters in habitual and non-habitual caffeine consumers.Other primary literatureHumanActiveClinical nutrition ESPEN2021
Caliskan SG, Kilic MA, Bilgin MD
Biological, histological and immunohistochemical studies on the toxicity of spent coffee grounds and caffeine on the larvae of Aedes aegypti (Diptera: Culicidae).Other primary literatureAnimalActiveEnvironmental pollution (Barking, Essex : 1987)2021
Miranda FR, Fernandes KM, Bernardes RC, et al.
Topically instilled caffeine selectively alters emmetropizing responses in infant rhesus monkeys.Other primary literatureAnimalActiveExperimental eye research2021
Smith EL 3rd, Hung LF, She Z, et al.
Copper nickel co-impregnation of Moroccan yellow clay as promising catalysts for the catalytic wet peroxide oxidation of caffeine.Other primary literatureUnknownActiveHeliyon2021
Assila O, Zouheir M, Tanji K, et al.
Optimization of betaine-sorbitol natural deep eutectic solvent-based ultrasound-assisted extraction and pancreatic lipase inhibitory activity of chlorogenic acid and caffeine content from robusta green coffee beans.Other primary literatureUnknownActiveHeliyon2021
Ahmad I, Syakfanaya AM, Azminah A, et al.
Caffeine, a natural methylxanthine nutraceutical, exerts dopaminergic neuroprotection.Other primary literatureAnimalActiveNeurochemistry international2021
Karuppagounder SS, Uthaythas S, Govindarajulu M, et al.
Caffeine exposure in utero is associated with structural brain alterations and deleterious neurocognitive outcomes in 9-10 year old children.Other primary literatureHumanActiveNeuropharmacology2021
Christensen ZP, Freedman EG, Foxe JJ
Stimulants cocktail: Methylphenidate plus caffeine impairs memory and cognition and alters mitochondrial and oxidative status.Other primary literatureAnimalActiveProgress in neuro-psychopharmacology & biological psychiatry2021
Freddo N, Soares SM, Fortuna M, et al.
The roles of HO•, ClO• and BrO• radicals in caffeine degradation: A theoretical study.Other primary literatureHumanActiveThe Science of the total environment2021
Li M, Mei Q, Han D, et al.
Caffeine adsorptive performance and compatibility characteristics (Eisenia foetida Savigny) of agro-industrial residues potentially suitable for vermifilter beds.Other primary literatureAnimalActiveThe Science of the total environment2021
Almeida-Naranjo CE, Frutos M, Tejedor J, et al.
Caffeine disrupts ataxia telangiectasia mutated gene-related pathways and exacerbates acetaminophen toxicity in human fetal immortalized hepatocytes.Other primary literatureHumanActiveToxicology2021
Viswanathan P, Gupta P, Sharma Y, et al.
Long-term ecotoxicological effects of ciprofloxacin in combination with caffeine on the microalga Raphidocelis subcapitata.Other primary literatureUnknownActiveToxicology reports2021
Diniz V, Rath G, Rath S, et al.
LC-MS/MS method for rapid and accurate detection of caffeine in a suspected overdose case.Other primary literatureUnknownActiveJournal of pharmacological and toxicological methods2021
Usui K, Fujita Y, Kamijo Y, et al.
Severe Caffeine Intoxication Treated With Hemodialysis: A Case Report.Other primary literatureUnknownActiveKidney medicine2021
Elbokl M, Randall I, Lok C
New framework for a non-animal approach adequately assures the safety of cosmetic ingredients - A case study on caffeine.Other primary literatureHuman & animalActiveRegulatory toxicology and pharmacology : RTP2021
Bury D, Alexander-White C, Clewell HJ 3rd, et al.
Recent consumption of a caffeine-containing beverage and serum biomarkers of cardiometabolic function in the UK Biobank.Other primary literatureHumanActiveThe British journal of nutrition2021
Cornelis MC
Does coffee, tea and caffeine consumption reduce the risk of incident breast cancer? A systematic review and network meta-analysis.Systematic reviewHumanActivePublic health nutrition2021
Wang S, Li X, Yang Y, et al.
Enthalpies of Immersion in Caffeine and Glyphosate Aqueous Solutions of SBA-15 and Amino-Functionalized SBA-15.Other primary literatureUnknownActiveACS omega2021
Rodríguez-Estupiñan P, Correa-Navarro YM, Vargas DP, et al.
Caffeine consumption, toxicity, tolerance and withdrawal; shared genetic influences with normative personality and personality disorder traits.Other primary literatureHumanActiveExperimental and clinical psychopharmacology2021
Czajkowski N, Kendler KS, Torvik FA, et al.
Caffeine promotes angiogenesis through modulating endothelial mitochondrial dynamics.Other primary literatureHuman & animalActiveActa pharmacologica Sinica2021
Wang LT, He PC, Li AQ, et al.
Stimulatory, but not anxiogenic, doses of caffeine act centrally to activate interscapular brown adipose tissue thermogenesis in anesthetized male rats.Other primary literatureAnimalActiveScientific reports2021
Van Schaik L, Kettle C, Green R, et al.
Caffeine increases performance and leads to a cardioprotective effect during intense exercise in cyclists.Randomized controlled trialHumanActiveScientific reports2021
Sampaio-Jorge F, Morales AP, Pereira R, et al.
Caffeine may disrupt the impact of real-time drowsiness on cognitive performance: a double-blind, placebo-controlled small-sample study.Other primary literatureHumanActiveScientific reports2021
Aidman E, Balin M, Johnson K, et al.
The impact of daily caffeine intake on nighttime sleep in young adult men.Randomized controlled trialHumanActiveScientific reports2021
Weibel J, Lin YS, Landolt HP, et al.
An electrochemical sensor for nanomolar detection of caffeine based on nicotinic acid hydrazide anchored on graphene oxide (NAHGO).Other primary literatureUnknownActiveScientific reports2021
Jose J, Subramanian V, Shaji S, et al.
Effects of Neonatal Caffeine Administration on Vessel Reactivity in Adult Mice.Other primary literatureAnimalActiveAmerican journal of perinatology2021
Singh AP, Chandrasekharan P, Gugino S, et al.
Removal of 17α-ethinylestradiol and caffeine from wastewater by UASB-Fenton coupled system.Other primary literatureUnknownActiveEnvironmental technology2021
López-Velázquez K, Villanueva-Rodríguez M, Mejía-González G, et al.
Ilex paraguariensis extract provides increased resistance against oxidative stress and protection against Amyloid beta-induced toxicity compared to caffeine in Caenorhabditis elegans.Other primary literatureAnimalActiveNutritional neuroscience2021
Machado ML, Arantes LP, da Silveira TL, et al.
Neuromotor activity inhibition in zebrafish early-life stages after exposure to environmental relevant concentrations of caffeine.Other primary literatureAnimalActiveJournal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering2021
de Farias NO, de Sousa Andrade T, Santos VL, et al.
Students' use of caffeine, alcohol, dietary supplements, and illegal substances for improving academic performance in a New Zealand university.Other primary literatureUnknownActiveHealth psychology and behavioral medicine2021
Narayanan A, Gill M, Leem C, et al.
Caffeine consumption attenuates ethanol-induced inflammation through the regulation of adenosinergic receptors in the UChB rats cerebellum.Other primary literatureUnknownActiveToxicology research2021
Rossetto IMU, Cagnon VHA, Kido LA, et al.
Prenatal caffeine exposure caused H-type blood vessel-related long bone dysplasia via miR375/CTGF signaling.Other primary literatureAnimalCorrectedFASEB journal : official publication of the Federation of American Societies for Experimental Biology2021
He H, Luo H, Liu L, et al.
Maternal caffeine consumption and pregnancy outcomes: a narrative review with implications for advice to mothers and mothers-to-be.ReviewHumanActiveBMJ evidence-based medicine2021
James JE
Caffeine for the care of preterm infants in sub-Saharan Africa: a missed opportunity?Other primary literatureHumanActiveBMJ global health2021
Nabwera HM, Ekhaguere OA, Kirpalani H, et al.
Multicentre, randomised trial of preterm infants receiving caffeine and less invasive surfactant administration compared with caffeine and early continuous positive airway pressure (CaLI trial): study protocol.Other primary literatureHumanActiveBMJ open2021
Ines F, Hutson S, Coughlin K, et al.
Short-Term Influence of Caffeine and Medium-Chain Triglycerides on Ketogenesis: A Controlled Double-Blind Intervention Study.Other primary literatureUnknownActiveJournal of nutrition and metabolism2021
Baumeister A, Gardemann J, Fobker M, et al.
The Effect of Toothpastes Containing Natural Ingredients Such As Theobromine and Caffeine on Enamel Microhardness: An In Vitro Study.Other primary literatureUnknownActiveEvidence-based complementary and alternative medicine : eCAM2021
Golfeshan F, Mosaddad SA, Ghaderi F
The Neuroprotective Effects of Moderate and Regular Caffeine Consumption in Alzheimer's Disease.ReviewHuman & animalActiveOxidative medicine and cellular longevity2021
Zhou X, Zhang L
Effects of Caffeine Supplementation on Physical Performance of Soccer Players: Systematic Review and Meta-Analysis.Meta-analysisHumanActiveSports health2021
Ferreira RES, Pacheco RL, de Oliveira Cruz Latorraca C, et al.
Use of therapeutic caffeine in acute care postoperative and critical care settings: a scoping review.Other primary literatureHumanActiveBMC anesthesiology2021
Bright M, Raman V, Laupland KB
Caffeine-induced hypokalemia: a case report.Other primary literatureHumanActiveBMC nephrology2021
Han MJ, Kim SH, Shin JH, et al.
Caffeine-clozapine interaction associated with severe toxicity and multiorgan system failure: a case report.Other primary literatureHumanActiveBMC psychiatry2021
Yartsev A, Peisah C
Effects of supplementation with main coffee components including caffeine and/or chlorogenic acid on hepatic, metabolic, and inflammatory indices in patients with non-alcoholic fatty liver disease and type 2 diabetes: a randomized, double-blind, placebo-controlled, clinical trial.Randomized controlled trialHumanActiveNutrition journal2021
Mansour A, Mohajeri-Tehrani MR, Samadi M, et al.
International society of sports nutrition position stand: caffeine and exercise performance.ReviewHumanActiveJournal of the International Society of Sports Nutrition2021
Guest NS, VanDusseldorp TA, Nelson MT, et al.
Caffeine improves biochemical and specific performance after judo training: a double-blind crossover study in a real judo training situation.Other primary literatureUnknownActiveNutrition & metabolism2021
Carmo KEO, Pérez DIV, Valido CN, et al.
Suicidal attempt with caffeine overdose treated with dexmedetomidine: a case report.Other primary literatureHumanActiveJournal of medical case reports2021
Kitano T, Okajima M, Sato K, et al.
Pharmacokinetics of caffeine self-administered in overdose in a Japanese patient admitted to hospital.Other primary literatureUnknownActiveJournal of pharmaceutical health care and sciences2021
Adachi K, Beppu S, Terashima M, et al.
The Effects of Intraoperative Caffeine on Postoperative Opioid Consumption and Related Outcomes After Laparoscopic Surgery: A Randomized Controlled Trial.Randomized controlled trialHumanActiveAnesthesia and analgesia2021
Vlisides PE, Li D, McKinney A, et al.
Association between self-reported caffeine intake during pregnancy and social responsiveness scores in childhood: The EARLI and HOME studies.Other primary literatureHumanActivePloS one2021
Patti MA, Li N, Eliot M, et al.
The effect of caffeine on tinnitus: Randomized triple-blind placebo-controlled clinical trial.Randomized controlled trialHumanActivePloS one2021
Ledesma ALL, Leite Rodrigues D, Monteiro de Castro Silva I, et al.
Caffeine: cardiorespiratory effects and tissue protection in animal models.ReviewAnimalActiveExperimental animals2021
Villanueva-García D, Mota-Rojas D, Miranda-Cortés A, et al.
Caffeine modulates pharmacokinetic and pharmacodynamic profiles of pioglitazone in diabetic rats: Impact on therapeutics.Other primary literatureHuman & animalActiveSaudi medical journal2021
Alshabi AM, Alkahtani SA, Shaikh IA, et al.
Caffeine intake reduces sedentary time and increases physical activity predisposition in obese police officers.Other primary literatureHumanActiveBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas2021
Ferreira GA, Wagner L, Maziero R, et al.
A systematic review of caffeine-related suicides and an analysis of the controversial role of caffeine consumption in suicidal risk.Systematic reviewHumanActiveRivista di psichiatria2021
Cappelletti S, Piacentino D, Ciallella C
Caffeine content and antioxidant activity of various brews of specialty grade coffee.Other primary literatureHumanActiveActa scientiarum polonorum. Technologia alimentaria2021
Miłek M, Młodecki Ł, Dżugan M
The comparison of post-dural puncture headache treatment with acetaminophen-caffeine capsule and intravenous mannitol infusion: A randomized single-blind clinical trial.Other primary literatureUnknownActiveCurrent journal of neurology2021
Shahriari A, Nataj-Majd M, Khooshideh M, et al.
Psoralidin prevents caffeine-induced damage and abnormal differentiation of bone marrow mesenchymal stem cells via the classical estrogen receptor pathway.Other primary literatureUnknownActiveAnnals of translational medicine2021
Hua R, Zou J, Ma Y, et al.
Metabolic Syndrome Associated with Tobacco and Caffeine Products Use Among Refugee Adolescents: Risk of Dyslipidemia.Other primary literatureUnknownActiveDiabetes, metabolic syndrome and obesity : targets and therapy2021
Damiri B, Khatib O, Nazzal Z, et al.
A Neurochemical and Electrophysiological Study on the Combined Effects of Caffeine and Nicotine in the Cortex of Rats.Other primary literatureUnknownActiveBasic and clinical neuroscience2021
Mourad IM, Noor NA, Mohammed HS, et al.
Retinoic Acid Signaling Plays a Crucial Role in Excessive Caffeine Intake-Disturbed Apoptosis and Differentiation of Myogenic Progenitors.Other primary literatureUnknownActiveFrontiers in cell and developmental biology2021
Wu N, Li Y, He X, et al.
Caffeine Inhibits Choroidal Neovascularization Through Mitigation of Inflammatory and Angiogenesis Activities.Other primary literatureUnknownActiveFrontiers in cell and developmental biology2021
Sorenson CM, Song YS, Zaitoun IS, et al.
Caffeine Induces Autophagy and Apoptosis in Auditory Hair Cells via the SGK1/HIF-1α Pathway.Other primary literatureUnknownActiveFrontiers in cell and developmental biology2021
Tang X, Sun Y, Xu C, et al.
Cultivation and Genome Sequencing of Bacteria Isolated From the Coffee Berry Borer (Hypothenemus hampei), With Emphasis on the Role of Caffeine Degradation.Other primary literatureUnknownActiveFrontiers in microbiology2021
Vega FE, Emche S, Shao J, et al.
Natural Plant Compounds: Does Caffeine, Dipotassium Glycyrrhizinate, Curcumin, and Euphol Play Roles as Antitumoral Compounds in Glioblastoma Cell Lines?ReviewUnknownActiveFrontiers in neurology2021
Bonafé GA, Boschiero MN, Sodré AR, et al.
Delirium, Caffeine, and Perioperative Cortical Dynamics.Other primary literatureUnknownActiveFrontiers in human neuroscience2021
Kim H, McKinney A, Brooks J, et al.
Effects of Caffeine on Brown Adipose Tissue Thermogenesis and Metabolic Homeostasis: A Review.ReviewUnknownActiveFrontiers in neuroscience2021
Van Schaik L, Kettle C, Green R, et al.
Caffeine and EGCG Alleviate High-Trans Fatty Acid and High-Carbohydrate Diet-Induced NASH in Mice: Commonality and Specificity.Other primary literatureUnknownActiveFrontiers in nutrition2021
Xin X, Cheng C, Bei-Yu C, et al.
Time to Recover From Daily Caffeine Intake.Other primary literatureUnknownActiveFrontiers in nutrition2021
Lin YS, Weibel J, Landolt HP, et al.
Encephalopathy in Preterm Infants: Advances in Neuroprotection With Caffeine.ReviewUnknownActiveFrontiers in pediatrics2021
Yang L, Yu X, Zhang Y, et al.
Inhibition of Caffeine Metabolism by Apiaceous and Rutaceae Families of Plant Products in Humans: In Vivo and In Vitro Studies.Other primary literatureUnknownActiveFrontiers in pharmacology2021
Alehaideb Z, Sheriffdeen M, Law FCP
Caffeine for the Pharmacological Treatment of Apnea of Prematurity in the NICU: Dose Selection Conundrum, Therapeutic Drug Monitoring and Genetic Factors.ReviewUnknownActiveFrontiers in pharmacology2021
Long JY, Guo HL, He X, et al.
Caffeine Therapy for Apnea of Prematurity: Role of the Circadian CLOCK Gene Polymorphism.Other primary literatureUnknownActiveFrontiers in pharmacology2021
Guo HL, Long JY, Hu YH, et al.
Pharmacokinetics of Caffeine: A Systematic Analysis of Reported Data for Application in Metabolic Phenotyping and Liver Function Testing.ReviewUnknownActiveFrontiers in pharmacology2021
Grzegorzewski J, Bartsch F, Köller A, et al.
The Cardiac Effects of Performance-Enhancing Medications: Caffeine vs. Anabolic Androgenic Steroids.ReviewUnknownActiveDiagnostics (Basel, Switzerland)2021
Sivalokanathan S, Małek ŁA, Malhotra A
Role of Coffee Caffeine and Chlorogenic Acids Adsorption to Polysaccharides with Impact on Brew Immunomodulation Effects.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2021
Passos CP, Costa RM, Ferreira SS, et al.
Genetic Determinants of Neurobehavioral Responses to Caffeine Administration during Sleep Deprivation: A Randomized, Cross Over Study (NCT03859882).Randomized controlled trialHumanActiveGenes2021
Erblang M, Sauvet F, Drogou C, et al.
A Randomized Controlled Trial Comparing Two Doses of Caffeine for Apnoea in Prematurity.Randomized controlled trialHumanActiveInternational journal of environmental research and public health2021
Mohd Kori AM, Van Rostenberghe H, Ibrahim NR, et al.
Market Expansion of Caffeine-Containing Products: Italian and Argentinian Yerba Mate Consumer Behavior and Health Perception.Other primary literatureHumanActiveInternational journal of environmental research and public health2021
Samoggia A, Landuzzi P, Vicién CE
Effects of Caffeine and Caffeinated Beverages in Children, Adolescents and Young Adults: Short Review.ReviewHumanActiveInternational journal of environmental research and public health2021
Soós R, Gyebrovszki Á, Tóth Á, et al.
Pharmacodynamic Effects of Standard versus High Caffeine Doses in the Developing Brain of Neonatal Rats Exposed to Intermittent Hypoxia.Other primary literatureAnimalActiveInternational journal of molecular sciences2021
Soontarapornchai K, Cai CL, Ahmad T, et al.
Caffeine-Cyclodextrin Complexes as Solids: Synthesis, Biological and Physicochemical Characterization.Other primary literatureAnimalActiveInternational journal of molecular sciences2021
Szmeja S, Gubica T, Ostrowski A, et al.
Caffeine Inhibits Direct and Indirect Angiogenesis in Zebrafish Embryos.Other primary literatureHuman & animalActiveInternational journal of molecular sciences2021
Basnet RM, Zizioli D, Muscò A, et al.
Possible Beneficial Actions of Caffeine in SARS-CoV-2.ReviewHumanActiveInternational journal of molecular sciences2021
Romero-Martínez BS, Montaño LM, Montaño LM, et al.
Acute Effects of High Doses of Caffeine on Bar Velocity during the Bench Press Throw in Athletes Habituated to Caffeine: A Randomized, Double-Blind and Crossover Study.Other primary literatureUnknownActiveJournal of clinical medicine2021
Filip-Stachnik A, Krzysztofik M, Del Coso J, et al.
Chemical Changes of Wood Treated with Caffeine.Other primary literatureUnknownActiveMaterials (Basel, Switzerland)2021
Kwaśniewska-Sip P, Woźniak M, Jankowski W, et al.
Caffeine Health Claims on Sports Supplement Labeling. Analytical Assessment According to EFSA Scientific Opinion and International Evidence and Criteria.Observational studyHumanActiveMolecules (Basel, Switzerland)2021
Estevan Navarro P, Sospedra I, Perales A, et al.
Targeting Melanoma-Initiating Cells by Caffeine: In Silico and In Vitro Approaches.Other primary literatureHumanActiveMolecules (Basel, Switzerland)2021
Tabolacci C, Cordella M, Rossi S, et al.
Novel Facet of an Old Dietary Molecule? Direct Influence of Caffeine on Glucose and Biogenic Amine Handling by Human Adipocytes.Other primary literatureHuman & animalActiveMolecules (Basel, Switzerland)2021
Ahmed WH, Boulet N, Briot A, et al.
Degradation of Neonicotinoids and Caffeine from Surface Water by Photolysis.Other primary literatureUnknownActiveMolecules (Basel, Switzerland)2021
Raschitor A, Romero A, Sanches S, et al.
Potential of Caffeine in Alzheimer's Disease-A Review of Experimental Studies.ReviewHuman & animalActiveNutrients2021
Londzin P, Zamora M, Kąkol B, et al.
Caffeine Consumption Habits of New Zealand Tertiary Students.Other primary literatureHumanActiveNutrients2021
Stachyshyn S, Ali A, Wham C, et al.
Effects of Daily Matcha and Caffeine Intake on Mild Acute Psychological Stress-Related Cognitive Function in Middle-Aged and Older Adults: A Randomized Placebo-Controlled Study.Randomized controlled trialHumanActiveNutrients2021
Baba Y, Baba Y, Inagaki S, et al.
Caffeine Sources and Consumption among Saudi Adults Living with Diabetes and Its Potential Effect on HbA1c.Other primary literatureHumanActiveNutrients2021
Albar SA, Almaghrabi MA, Bukhari RA, et al.
Caffeine Consumption in a Group of Adolescents from South East Poland-A Cross Sectional Study.Other primary literatureHumanActiveNutrients2021
Błaszczyk-Bębenek E, Jagielski P, Schlegel-Zawadzka M
Long-Term Caffeine Intake Exerts Protective Effects on Intestinal Aging by Regulating Vitellogenesis and Mitochondrial Function in an Aged Caenorhabditis Elegans Model.Other primary literatureAnimalActiveNutrients2021
Min H, Youn E, Shim YH
Coffee and Caffeine Consumption for Human Health.Other primary literatureHumanActiveNutrients2021
Abalo R
Caffeine as a Factor Influencing the Functioning of the Human Body-Friend or Foe?ReviewHuman & animalActiveNutrients2021
Rodak K, Kokot I, Kratz EM
The Dose-Effects of Caffeine on Lower Body Maximal Strength, Muscular Endurance, and Rating of Perceived Exertion in Strength-Trained Females.Other primary literatureHumanActiveNutrients2021
Jones L, Johnstone I, Day C, et al.
Does Acute Caffeine Supplementation Improve Physical Performance in Female Team-Sport Athletes? Evidence from a Systematic Review and Meta-Analysis.Meta-analysisHumanActiveNutrients2021
Gomez-Bruton A, Marin-Puyalto J, Muñiz-Pardos B, et al.
Motivations for Caffeine Consumption in New Zealand Tertiary Students.Other primary literatureHumanActiveNutrients2021
Stachyshyn S, Wham C, Ali A, et al.
Formulation and In Vitro Evaluation of Pellets Containing Sulfasalazine and Caffeine to Verify Ileo-Colonic Drug Delivery.Other primary literatureUnknownActivePharmaceutics2021
Broesder A, Bircan SY, de Waard AB, et al.
Efficacy of Caffeine Treatment for Wood Protection-Influence of Wood and Fungi Species.Other primary literatureUnknownActivePolymers2021
Pánek M, Borůvka V, Nábělková J, et al.
Pleiotropic Effects of Caffeine Leading to Chromosome Instability and Cytotoxicity in Eukaryotic Microorganisms.ReviewUnknownActiveJournal of microbiology and biotechnology2021
Chung WH
Prediction of pharmacokinetic values of two various dosages of caffeine in premature neonates with apnea.Other primary literatureHumanActiveIndian journal of pharmacology2021
Faramarzi F, Shiran M, Rafati M, et al.
Melatonin-Caffeine Combination Modulates Gamma Radiation-induced Sperm Malformations in C57BL/6 Male Mice at Sublethal Dose of Gamma Radiation.Other primary literatureUnknownActiveJournal of pharmacy & bioallied sciences2021
Kushwaha R, Nishad DK, Bhatnagar A, et al.
Linear concentration-response relationship of serum caffeine with adenosine-induced fractional flow reserve overestimation: a comparison with papaverine.Other primary literatureHumanActiveEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2021
Tanaka H, Matsumoto H, Takahashi H, et al.
The prevalence and practices of caffeine use as an ergogenic aid in English professional soccer.Other primary literatureUnknownActiveBiology of sport2021
Tallis J, Clarke N, Morris R, et al.
Acute effects of consumption of low-caffeine energy drinks on endothelial functions in healthy volunteers.Other primary literatureHumanActiveAnatolian journal of cardiology2021
Akhundova J, Kaya CT, Gerede Uludağ DM
Association of long-term inhalation of caffeine-sodium benzoate with coronary heart disease in men.Other primary literatureHumanActiveInternational journal of clinical pharmacology and therapeutics2021
Pan SC, Cui HH, Si GG, et al.
Oral Testofen, L-Citrulline, Resveratrol, and Caffeine Supplement Drink Improves Sexual Function in Men with Phosphodiesterase 5 Inhibitors: Randomized, Double-Blind, Placebo-Controlled Crossover Pilot Study.Other primary literatureUnknownActiveThe world journal of men's health2021
Shirai M, Miyoshi Y, Ogasa T, et al.
An Evaluation of Twice-Daily Dosing of Caffeine for Apnea of Prematurity.Other primary literatureUnknownActiveThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG2021
Rebentisch A, Kovey K, Denslow S
Evaluation of the Use of Caffeine Citrate Maintenance Doses >5 mg/kg/day in Preterm Neonates for Apnea of Prematurity.Other primary literatureUnknownActiveThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG2021
Salemi LA, Sahlstrom AL, Lim SY, et al.
Effects of Caffeine on Exercise Duration, Critical Velocity, and Ratings of Perceived Exertion During Repeated-Sprint Exercise in Physically Active Men.Other primary literatureUnknownActiveInternational journal of exercise science2021
Stein JA, Gasier HG, Goodman BD, et al.
Effect of different maintenance doses of caffeine citrate on ventilator weaning in very preterm infants with respiratory distress syndrome: a prospective randomized controlled trial.Randomized controlled trialHumanActiveZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2021
Li XL, Cai YJ, Zhang Z, et al.
Caffeine-Induced Severe Erosive Esophagitis.Other primary literatureUnknownActiveCureus2021
Arhinful JS, Arhinful B, Akins TA, et al.
The Relationship Between Caffeine and Caffeinated Drinks in Causing Intracranial Hemorrhage in the Elderly Aspirin-Taking Population: A Systematic Review.ReviewUnknownActiveCureus2021
Khan A, Abdalla MA, Zakhary CM, et al.
Caffeine Intoxication Due to Antipyretic Analgesic Overdose in an Adolescent.Other primary literatureUnknownActiveCureus2021
Horikawa Y, Yatsuga S, Okamatsu Y
Presentation of Caffeine Intoxication in an Active Duty Service Member Originally Believed to Have a Psychotic Disorder.Other primary literatureUnknownActiveCureus2021
Duncan A, Dixon D
Assessment of the Relationship of Depression With Tobacco and Caffeine Use Among University Students: A Cross-Sectional Study.Other primary literatureUnknownActiveCureus2021
Safarini OA, Taya H, Abu Elhija Y, et al.
Association of Weight-Adjusted Caffeine and β-Blocker Use With Ophthalmology Fellow Performance During Simulated Vitreoretinal Microsurgery.Other primary literatureHumanActiveJAMA ophthalmology2020
Roizenblatt M, Dias Gomes Barrios Marin V, Grupenmacher AT, et al.
Urinary glucose and ketone bodies as indicators of acute caffeine poisoning.Other primary literatureUnknownActiveAcute medicine & surgery2020
Morita S, Tsuji T, Amino M, et al.
Propofol suppresses ventricular arrhythmias: a case report of acute caffeine intoxication.Other primary literatureUnknownActiveAcute medicine & surgery2020
Terashima S, Muroya T, Ikegawa H, et al.
Serum potassium level as a biomarker for acute caffeine poisoning.Other primary literatureUnknownActiveAcute medicine & surgery2020
Tsuji T, Morita S, Saito T, et al.
Caffeine citrate maintenance doses effect on extubation and apnea postventilation in preterm infants.Randomized controlled trialHumanActivePediatric pulmonology2020
Wan L, Huang L, Chen P
Caffeine intake and cognitive functions in children.Other primary literatureHumanActivePsychopharmacology2020
Zhang H, Lee ZX, Qiu A
Time course of tolerance to adverse effects associated with the ingestion of a moderate dose of caffeine.Other primary literatureHumanActiveEuropean journal of nutrition2020
Ruiz-Moreno C, Lara B, Salinero JJ, et al.
The adulterated XANAX pill: a fatal intoxication with etizolam and caffeine.Other primary literatureHumanActiveInternational journal of legal medicine2020
Kolbe V, Rentsch D, Boy D, et al.
Occurrence, fate, persistence and remediation of caffeine: a review.ReviewHumanActiveEnvironmental science and pollution research international2020
Korekar G, Kumar A, Ugale C
The Impact of Baseline Pain Intensity on the Analgesic Efficacy of Ibuprofen/Caffeine in Patients with Acute Postoperative Dental Pain: Post Hoc Subgroup Analysis of a Randomised Controlled Trial.Randomized controlled trialHumanActiveAdvances in therapy2020
Förderreuther S, Lampert A, Hitier S, et al.
Pill-induced esophagitis caused by ingesting excessive caffeine tablets.Other primary literatureHumanActiveClinical journal of gastroenterology2020
Miyata J, Ito Y, Ito S
Is Impregnation of Xenograft with Caffeine Effective on Bone Healing Rate in Mandibular Defects? A Pilot Histological Animal Study.Other primary literatureUnknownActiveJournal of maxillofacial and oral surgery2020
Samieirad S, Mianbandi V, Salari Sedigh H, et al.
Design & development of nanosponge loaded topical gel of curcumin and caffeine mixture for augmented treatment of psoriasis.Other primary literatureAnimalActiveDaru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences2020
Iriventi P, Gupta NV, Osmani RAM, et al.
Caffeine for the Treatment of Apnea in the Neonatal Intensive Care Unit: A Systematic Overview of Meta-Analyses.Systematic reviewHumanActivePaediatric drugs2020
Alhersh E, Abushanab D, Al-Shaibi S, et al.
Acute intentional caffeine overdose treated preemptively with hemodialysis.Other primary literatureHumanActiveThe American journal of emergency medicine2020
Kohl BA, Kaur K, Dincher N, et al.
Hemodialysis removal of caffeine.Other primary literatureHumanActiveThe American journal of emergency medicine2020
Ghannoum M, Hoffman RS, Roberts DM, et al.
Caffeine treatment for bronchiolitis-related apnea in the pediatric intensive care unit.Other primary literatureHumanActiveArchives de pediatrie : organe officiel de la Societe francaise de pediatrie2020
Heuzé N, Goyer I, Porcheret F, et al.
Risks of caffeine residues in the environment: Necessity for a targeted ecopharmacovigilance program.ReviewAnimalActiveChemosphere2020
Li S, He B, Wang J, et al.
High-Dose Insulin Euglycemic Therapy in the Treatment of a Massive Caffeine Overdose.Other primary literatureHumanActiveChest2020
Hensher C, Vogel J
Data on the relationship between caffeine addiction and stress among Lebanese medical students in Lebanon.Other primary literatureUnknownActiveData in brief2020
Samaha A, Al Tassi A, Yahfoufi N, et al.
GR/HDAC2/TGFβR1 pathway contributes to prenatal caffeine induced-osteoarthritis susceptibility in male adult offspring rats.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2020
Li J, Xiao H, Luo H, et al.
Alcoholic fermentation as a potential tool for coffee pulp detoxification and reuse: Analysis of phenolic composition and caffeine content by HPLC-DAD-MS/MS.Other primary literatureUnknownActiveFood chemistry2020
da Silveira JS, Mertz C, Morel G, et al.
Caffeine and dobutamine challenge induces bidirectional ventricular tachycardia in normal rats.Other primary literatureUnknownActiveHeart rhythm O22020
Zhang C, Zhang Y
Extracorporeal Membrane Oxygenation for Hypokalemia and Refractory Ventricular Fibrillation Associated with Caffeine Intoxication.Other primary literatureUnknownActiveThe Journal of emergency medicine2020
Kato Y, Kuriyama A, Hata R, et al.
Consider Going Decaf: An Intentional Caffeine Overdose in the Emergency Department.Other primary literatureHumanActiveThe Journal of emergency medicine2020
Meester S, Hogrefe C
Caffeine induces neurobehavioral effects through modulating neurotransmitters.ReviewUnknownActiveSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2020
Alasmari F
Adverse Events Reported to the United States Food and Drug Administration Related to Caffeine-Containing Products.Other primary literatureHumanActiveMayo Clinic proceedings2020
Jagim AR, Harty PS, Fischer KM, et al.
Why Are Certain Caffeine-Containing Products Associated With Serious Adverse Effects?Other primary literatureHumanActiveMayo Clinic proceedings2020
Lieberman HR
Multiple caffeine doses maintain vigilance, attention, complex motor sequence expression, and manual dexterity during 77 hours of total sleep deprivation.Other primary literatureUnknownActiveNeurobiology of sleep and circadian rhythms2020
Killgore WDS, Kamimori GH
Do caffeine and more selective adenosine A2A receptor antagonists protect against dopaminergic neurodegeneration in Parkinson's disease?ReviewHuman & animalActiveParkinsonism & related disorders2020
Chen JF, Schwarzschild MA
Chronic voluntary caffeine intake in male Wistar rats reveals individual differences in addiction-like behavior.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior2020
Lee CH, George O, Kimbrough A
Neurodevelopmental outcomes after neonatal caffeine therapy.ReviewHuman & animalActiveSeminars in fetal & neonatal medicine2020
Synnes A, Grunau RE
Caffeine exposure during pregnancy: Is it safe?ReviewHumanActiveSeminars in fetal & neonatal medicine2020
Baptiste-Roberts K, Leviton A
When to start and stop caffeine and why respiratory status matters.Other primary literatureHumanActiveSeminars in fetal & neonatal medicine2020
Davis PG
Caffeine for preterm infants: Fixed standard dose, adjustments for age or high dose?ReviewHumanActiveSeminars in fetal & neonatal medicine2020
Saroha V, Patel RM
Pharmacokinetics, pharmacodynamics and metabolism of caffeine in newborns.Other primary literatureHumanActiveSeminars in fetal & neonatal medicine2020
Aranda JV, Beharry KD
Effective quantification of 11 tyrosine kinase inhibitors and caffeine in human plasma by validated LC-MS/MS method with potent phospholipids clean-up procedure. Application to therapeutic drug monitoring.Other primary literatureHumanActiveTalanta2020
Koller D, Vaitsekhovich V, Mba C, et al.
Impacts of Caffeine during Pregnancy.ReviewHuman & animalActiveTrends in endocrinology and metabolism: TEM2020
Qian J, Chen Q, Ward SM, et al.
Articular damages in multi-generational female offspring due to prenatal caffeine exposure correlates with H3K9 deacetylation of TGFβ signaling pathway.Other primary literatureAnimalActiveToxicology2020
Zhao Z, Qin J, Pei L, et al.
Exquisite Tumor Targeting by Salmonella A1-R in Combination with Caffeine and Valproic Acid Regresses an Adult Pleomorphic Rhabdomyosarcoma Patient-Derived Orthotopic Xenograft Mouse Model.Other primary literatureUnknownActiveTranslational oncology2020
Igarashi K, Kawaguchi K, Zhao M, et al.
Caffeine and Theophylline Inhibit β-Galactosidase Activity and Reduce Expression in Escherichia coli.Other primary literatureUnknownActiveACS omega2020
Horne J, Beddingfield E, Knapp M, et al.
Wide variation in caffeine discontinuation timing in premature infants.Other primary literatureHumanActiveJournal of perinatology : official journal of the California Perinatal Association2020
Ji D, Smith PB, Clark RH, et al.
Identification and characterization of N9-methyltransferase involved in converting caffeine into non-stimulatory theacrine in tea.Other primary literatureUnknownActiveNature communications2020
Zhang YH, Li YF, Wang Y, et al.
Neuronal adenosine A2A receptors signal ergogenic effects of caffeine.Other primary literatureAnimalActiveScientific reports2020
Aguiar AS Jr, Speck AE, Canas PM, et al.
Effects of L-theanine-caffeine combination on sustained attention and inhibitory control among children with ADHD: a proof-of-concept neuroimaging RCT.Randomized controlled trialHumanActiveScientific reports2020
Kahathuduwa CN, Wakefield S, West BD, et al.
Caffeine inhibits Notum activity by binding at the catalytic pocket.Other primary literatureHumanActiveCommunications biology2020
Zhao Y, Ren J, Hillier J, et al.
Caffeine reduces deficits in mechanosensation and locomotion induced by L-DOPA and protects dopaminergic neurons in a transgenic Caenorhabditis elegans model of Parkinson's disease.Other primary literatureAnimalCorrectedPharmaceutical biology2020
Manalo RVM, Medina PMB
Effects of Preinjury and Postinjury Exposure to Caffeine in a Rat Model of Traumatic Brain Injury.Other primary literatureUnknownActiveJournal of caffeine and adenosine research2020
Lusardi TA, Lytle NK, Gebril HM, et al.
Prevalence and Correlates of Caffeine Use Disorder Symptoms Among a United States Sample.Other primary literatureUnknownActiveJournal of caffeine and adenosine research2020
Sweeney MM, Weaver DC, Vincent KB, et al.
A model protocol for the cryopreservation and recovery of motile lizard sperm using the phosphodiesterase inhibitor caffeine.Other primary literatureUnknownActiveConservation physiology2020
Campbell L, Cafe SL, Upton R, et al.
Demographics, sleep, and daily patterns of caffeine intake of shift workers in a nationally representative sample of the US adult population.Other primary literatureHumanActiveSleep2020
Lieberman HR, Agarwal S, Caldwell JA, et al.
Effects of caffeine on brain antioxidant status and mitochondrial respiration in acetaminophen-intoxicated mice.Other primary literatureUnknownActiveToxicology research2020
Gonçalves DF, Tassi CC, Amaral GP, et al.
Caffeine Restrictions in Inpatient Psychiatric Settings: Precipitating Withdrawal?Other primary literatureHumanActiveJournal of addiction medicine2020
Shapiro B
The low-expression programming of 11β-HSD2 mediates osteoporosis susceptibility induced by prenatal caffeine exposure in male offspring rats.Other primary literatureAnimalActiveBritish journal of pharmacology2020
Xiao H, Wu Z, Li B, et al.
Associations of maternal caffeine intake during pregnancy with abdominal and liver fat deposition in childhood.Other primary literatureHumanActivePediatric obesity2020
Voerman E, Jaddoe VW, Hulst ME, et al.
Caffeine increases strength and power performance in resistance-trained females during early follicular phase.Randomized controlled trialHumanActiveScandinavian journal of medicine & science in sports2020
Norum M, Risvang LC, Bjørnsen T, et al.
The Effects of Caffeine Mouth Rinsing on Exercise Performance: A Systematic Review.Systematic reviewHumanActiveInternational journal of sport nutrition and exercise metabolism2020
Ehlert AM, Twiddy HM, Wilson PB
Effects of Caffeine Ingestion on Physical Performance in Elite Women Handball Players: A Randomized, Controlled Study.Randomized controlled trialHumanActiveInternational journal of sports physiology and performance2020
Muñoz A, López-Samanes Á, Pérez-López A, et al.
Dietary Caffeine Synergizes Adverse Peripheral and Central Responses to Anesthesia in Malignant Hyperthermia Susceptible Mice.Other primary literatureHuman & animalActiveMolecular pharmacology2020
Aleman M, Zhang R, Feng W, et al.
Intralipid and haemodialysis in caffeine overdose.Other primary literatureHumanActiveBMJ case reports2020
Harsten R, Tetlow SJ, Chan T, et al.
(Rad 8)Caffeine prophylaxis to improve intermittent hypoxaemia in infants born late preterm: a randomised controlled dosage trial (Latte Dosage Trial).Randomized controlled trialHumanCorrectedBMJ open2020
Oliphant EA, McKinlay CJD, McNamara DG, et al.
Study protocol: treatment with caffeine of the very preterm infant in the delivery room: a feasibility study.Other primary literatureHumanActiveBMJ open2020
Dani C, Cecchi A, Remaschi G, et al.
Caffeine prevents prostaglandin E1-induced disturbances in respiratory control in neonatal rats: implications for infants with critical congenital heart disease.Other primary literatureAnimalActiveAmerican journal of physiology. Regulatory, integrative and comparative physiology2020
Mitchell LJ, Mayer CA, Mayer A, et al.
Prevention of Oxygen-Induced Inflammatory Lung Injury by Caffeine in Neonatal Rats.Other primary literatureHuman & animalActiveOxidative medicine and cellular longevity2020
Endesfelder S, Strauß E, Bendix I, et al.
Extraction-Free, Direct Determination of Caffeine in Microliter Volumes of Beverages by Thermal Desorption-Gas Chromatography Mass Spectrometry.Other primary literatureUnknownActiveInternational journal of analytical chemistry2020
Peng X, Brown M, Bowdler P, et al.
RP-HPLC and UV Spectrophotometric Analysis of Paracetamol, Ibuprofen, and Caffeine in Solid Pharmaceutical Dosage Forms by Derivative, Fourier, and Wavelet Transforms: A Comparison Study.Other primary literatureUnknownActiveJournal of analytical methods in chemistry2020
Vu Dang H, Truong Thi Thu H, Dong Thi Ha L, et al.
Caffeine Restores Background EEG Activity Independent of Infarct Reduction after Neonatal Hypoxic Ischemic Brain Injury.Other primary literatureAnimalActiveDevelopmental neuroscience2020
Sun H, Gonzalez F, McQuillen PS
Caffeine in preterm infants: where are we in 2020?ReviewUnknownActiveERJ open research2020
Moschino L, Zivanovic S, Hartley C, et al.
Neferine and lianzixin extracts have protective effects on undifferentiated caffeine-damaged PC12 cells.Other primary literatureAnimalActiveBMC complementary medicine and therapies2020
Chen J, Tang M, Liu M, et al.
Caffeine prevents hyperoxia-induced lung injury in neonatal mice through NLRP3 inflammasome and NF-κB pathway.Other primary literatureAnimalActiveRespiratory research2020
Chen S, Wu Q, Zhong D, et al.
The acute effects of thermogenic fitness drink formulas containing 140 mg and 100 mg of caffeine on energy expenditure and fat metabolism at rest and during exercise.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2020
Clark NW, Wells AJ, Coker NA, et al.
Modulation of CYP2E1 metabolic activity in a cohort of confirmed caffeine ingesting pregnant women with preterm offspring.Other primary literatureUnknownActiveMolecular and cellular pediatrics2020
Alcorta-García MR, López-Villaseñor CN, Sánchez-Ferrer G, et al.
Caffeine, alcohol, khat, and tobacco use during pregnancy in Butajira, South Central Ethiopia.Other primary literatureHumanActivePloS one2020
Alamneh AA, Endris BS, Gebreyesus SH
Caffeine reverses the unconsciousness produced by light anesthesia in the continued presence of isoflurane in rats.Other primary literatureAnimalActivePloS one2020
Fox AP, Wagner KR, Towle VL, et al.
Caffeine Intake During Pregnancy and Risk of Childhood Obesity: A Systematic Review.Other primary literatureUnknownActiveInternational journal of MCH and AIDS2020
Frayer NC, Kim Y
Caffeine-Induced Psychosis and a Review of Statutory Approaches to Involuntary Intoxication.ReviewHumanActiveThe journal of the American Academy of Psychiatry and the Law2020
Hearn JK, Reiff T, McBride AB, et al.
Associations Between Caffeine Consumption, Cognitive Decline, and Dementia: A Systematic Review.Systematic reviewHumanActiveJournal of Alzheimer's disease : JAD2020
Chen JQA, Scheltens P, Groot C, et al.
Caffeine Targets SIRT3 to Enhance SOD2 Activity in Mitochondria.Other primary literatureUnknownActiveFrontiers in cell and developmental biology2020
Xu H, Gan C, Gao Z, et al.
Sudden Caffeine Withdrawal Triggers Migraine-A Randomized Controlled Trial.Other primary literatureUnknownActiveFrontiers in neurology2020
Alstadhaug KB, Ofte HK, Müller KI, et al.
Caffeine and Parkinson's Disease: Multiple Benefits and Emerging Mechanisms.ReviewUnknownActiveFrontiers in neuroscience2020
Ren X, Chen JF
Caffeine Citrate for Apnea of Prematurity: A Prospective, Open-Label, Single-Arm Study in Chinese Neonates.Other primary literatureUnknownActiveFrontiers in pediatrics2020
Du L, Tong X, Chen C, et al.
Exposure to Morphine and Caffeine Induces Apoptosis and Mitochondrial Dysfunction in a Neonatal Rat Brain.Other primary literatureUnknownActiveFrontiers in pediatrics2020
Kasala S, Briyal S, Prazad P, et al.
The Influence of Placebo Effect on Craving and Cognitive Performance in Alcohol, Caffeine, or Nicotine Consumers: A Systematic Review.Systematic reviewUnknownActiveFrontiers in psychiatry2020
Galindo MN, Navarro JF, Cavas M
Effects of Caffeine on Egg Quality and Performance of Laying Hens.Other primary literatureUnknownActiveFrontiers in veterinary science2020
Teixeira MDS, Triginelli MV, Costa TA, et al.
Antioxidant and Neuroprotective Effects of Caffeine against Alzheimer's and Parkinson's Disease: Insight into the Role of Nrf-2 and A2AR Signaling.ReviewUnknownActiveAntioxidants (Basel, Switzerland)2020
Ikram M, Park TJ, Ali T, et al.
Effects of Various Doses of Caffeine Ingestion on Intermittent Exercise Performance and Cognition.Other primary literatureUnknownActiveBrain sciences2020
Wang C, Zhu Y, Dong C, et al.
The Effect of Low-Doses of Caffeine and Taurine on Convulsive Seizure Parameters in Rats.Other primary literatureUnknownActiveBehavioral sciences (Basel, Switzerland)2020
Jailani M, Mubarak M, Sarkhouh M, et al.
Discharging Preterm Infants Home on Caffeine, a Single Center Experience.Other primary literatureUnknownActiveChildren (Basel, Switzerland)2020
Ma C, Broadbent D, Levin G, et al.
Intake of Caffeine and Its Association with Physical and Mental Health Status among University Students in Bahrain.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2020
Jahrami H, Al-Mutarid M, Penson PE, et al.
FT-NIRS Coupled with PLS Regression as a Complement to HPLC Routine Analysis of Caffeine in Tea Samples.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2020
Ur Rehman N, Al-Harrasi A, Boqué R, et al.
Effects of CYP1A2 and ADORA2A Genotypes on the Ergogenic Response to Caffeine in Professional Handball Players.Other primary literatureHumanActiveGenes2020
Muñoz A, López-Samanes Á, Aguilar-Navarro M, et al.
Caffeine Consumption in Children: Innocuous or Deleterious? A Systematic Review.Systematic reviewHumanActiveInternational journal of environmental research and public health2020
Torres-Ugalde YC, Romero-Palencia A, Román-Gutiérrez AD, et al.
Caffeine: An Overview of Its Beneficial Effects in Experimental Models and Clinical Trials of Parkinson's Disease.ReviewHuman & animalActiveInternational journal of molecular sciences2020
Schepici G, Silvestro S, Bramanti P, et al.
Identification of Immune Regulatory Genes in Apis mellifera through Caffeine Treatment.Other primary literatureUnknownActiveInsects2020
Lu YH, Wu CP, Tang CK, et al.
Caffeine, a Risk Factor for Osteoarthritis and Longitudinal Bone Growth Inhibition.ReviewUnknownActiveJournal of clinical medicine2020
Guillán-Fresco M, Franco-Trepat E, Alonso-Pérez A, et al.
Caffeine and Gastric Emptying Time in Very Preterm Neonates.Other primary literatureUnknownActiveJournal of clinical medicine2020
Gounaris AK, Grivea IN, Baltogianni M, et al.
Exploring the Role of Caffeine Use in Adult-ADHD Symptom Severity of US Army Soldiers.Other primary literatureUnknownActiveJournal of clinical medicine2020
Cipollone G, Gehrman P, Manni C, et al.
Time Course and Magnitude of Tolerance to the Ergogenic Effect of Caffeine on the Second Ventilatory Threshold.Other primary literatureUnknownActiveLife (Basel, Switzerland)2020
Ruiz-Moreno C, Lara B, Gutiérrez-Hellín J, et al.
Comparative Performance of Citrate, Borohydride, Hydroxylamine and β-Cyclodextrin Silver Sols for Detecting Ibuprofen and Caffeine Pollutants by Means of Surface-Enhanced Raman Spectroscopy.Other primary literatureUnknownActiveNanomaterials (Basel, Switzerland)2020
Souza ML, Otero JC, López-Tocón I
ADOR2A C Allele Carriers Exhibit Ergogenic Responses to Caffeine Supplementation.Randomized controlled trialHumanActiveNutrients2020
Grgic J, Pickering C, Bishop DJ, et al.
Association of Coffee, Decaffeinated Coffee and Caffeine Intake from Coffee with Cognitive Performance in Older Adults: National Health and Nutrition Examination Survey (NHANES) 2011-2014.Other primary literatureHumanActiveNutrients2020
Dong X, Li S, Sun J, et al.
Motivations Influencing Caffeine Consumption Behaviors among College Students in Korea: Associations with Sleep Quality.Other primary literatureHumanActiveNutrients2020
Choi J
Maternal Caffeine Intake Disrupts Eggshell Integrity and Retards Larval Development by Reducing Yolk Production in a Caenorhabditis elegans Model.Other primary literatureAnimalActiveNutrients2020
Min H, Youn E, Shim YH
The Effect of Caffeine on the Risk and Progression of Parkinson's Disease: A Meta-Analysis.Meta-analysisHumanCorrectedNutrients2020
Hong CT, Chan L, Bai CH
Caffeine-Containing, Adaptogenic-Rich Drink Modulates the Effects of Caffeine on Mental Performance and Cognitive Parameters: A Double-Blinded, Placebo-Controlled, Randomized Trial.Other primary literatureHumanActiveNutrients2020
Boolani A, Fuller DT, Mondal S, et al.
Caffeine and Doping-What Have We Learned since 2004.Other primary literatureHumanActiveNutrients2020
Diel P
The Ambiguous Role of Caffeine in Migraine Headache: From Trigger to Treatment.ReviewHumanActiveNutrients2020
Nowaczewska M, Wiciński M, Kaźmierczak W
Saccharomyces cerevisiae and Caffeine Implications on the Eukaryotic Cell.ReviewHuman & animalActiveNutrients2020
Ruta LL, Farcasanu IC
Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human.ReviewHumanActiveNutrients2020
Jee HJ, Lee SG, Bormate KJ, et al.
Effects of Phosphoethanolamine Supplementation on Mitochondrial Activity and Lipogenesis in a Caffeine Ingestion Caenorhabditis elegans Model.Other primary literatureAnimalActiveNutrients2020
Min H, Youn E, Kim J, et al.
Caffeine-Containing Energy Shots Cause Acute Impaired Glucoregulation in Adolescents.Randomized controlled trialHumanActiveNutrients2020
Shearer J, Reimer RA, Hittel DS, et al.
Effects of Different Doses of Caffeinated Coffee on Muscular Endurance, Cognitive Performance, and Cardiac Autonomic Modulation in Caffeine Naive Female Athletes.Randomized controlled trialHumanActiveNutrients2020
Karayigit R, Naderi A, Akca F, et al.
The Effect of Caffeine and Trifluralin on Chromosome Doubling in Wheat Anther Culture.Other primary literatureUnknownActivePlants (Basel, Switzerland)2020
Broughton S, Castello M, Liu L, et al.
Caffeine versus aminophylline in combination with oxygen therapy for apnea of prematurity: A retrospective cohort study.Other primary literatureUnknownActiveExperimental and therapeutic medicine2020
Zhang CY, Liu DJ, Hua SD, et al.
Investigation of the Peripheral Analgesic Activity of Oxicams and Their Combinations with Caffeine.Other primary literatureUnknownActiveTurkish journal of pharmaceutical sciences2020
Syrova A, Lukyanova L, Kozub S, et al.
Caffeine Citrate for the Prevention of Apnea Associated With Alprostadil Infusions.Other primary literatureUnknownActiveThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG2020
Higgins KL, Buck ML
[Comparison of the efficacy of domestic and imported caffeine citrate in the treatment of apnea in preterm infants: a prospective randomized double-blind controlled trial].Randomized controlled trialHumanActiveZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2020
He T, Liao ZC, Ding Y, et al.
[Safety and efficacy of caffeine use started at different time in preterm infants: a multicenter study in Jiangsu Province, China].Other primary literatureHumanActiveZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2020
Yang Y, Cheng R, Wu Q, et al.
Flying From Hospital to Hospital: A Case of Caffeine Intoxication.Other primary literatureUnknownActiveCureus2020
Vilela M, Nogueira R, Cunha J, et al.
Caffeine as a Neoadjuvant Therapy in Parathyroid Adenomas: A Narrative Review.ReviewUnknownActiveCureus2020
Reddy MK, Murthy PM, Elsayed SM, et al.
Self-reported Quality of Life at Middle School Age in Survivors of Very Preterm Birth: Results From the Caffeine for Apnea of Prematurity Trial.Other primary literatureHumanActiveJAMA pediatrics2019
Schmidt B, Anderson PJ, Asztalos EV, et al.
Pharmacokinetic Properties of Ibuprofen (IBU) From the Fixed-Dose Combination IBU/Caffeine (400/100 mg; FDC) in Comparison With 400 mg IBU as Acid or Lysinate Under Fasted and Fed Conditions-Data From 2 Single-Center, Single-Dose, Randomized Crossover Studies in Healthy Volunteers.Randomized controlled trialHumanActiveClinical pharmacology in drug development2019
Weiser T, Schepers C, Mück T, et al.
Behavioral economic analysis of the reinforcing effects of "bath salts" mixtures: studies with MDPV, methylone, and caffeine in male Sprague-Dawley rats.Other primary literatureAnimalActivePsychopharmacology2019
Gannon BM, Mesmin MP, Sulima A, et al.
Randomized, double-blind, placebo-controlled, crossover study of the effects of repeated-dose caffeine on neurobehavioral performance during 48 h of total sleep deprivation.Randomized controlled trialHumanActivePsychopharmacology2019
Hansen DA, Ramakrishnan S, Satterfield BC, et al.
Effect of Caffeine on the Bioavailability and Pharmacokinetics of an Acetylsalicylic Acid-Paracetamol Combination: Results of a Phase I Study.Randomized controlled trialHumanActiveAdvances in therapy2019
Weiser T, Weigmann H
Alterations in the Gut Microbiota of Rats Chronically Exposed to Volatilized Cocaine and Its Active Adulterants Caffeine and Phenacetin.Other primary literatureAnimalActiveNeurotoxicity research2019
Scorza C, Piccini C, Martínez Busi M, et al.
Treatment of caffeine toxicity with metoprolol.Other primary literatureHumanActiveThe American journal of emergency medicine2019
Li SF, Edwards L, Nguyen V
Which of hemodialysis and direct hemoperfusion is more recommended for treating severe caffeine poisoning?Other primary literatureHumanActiveThe American journal of emergency medicine2019
Yoshizawa T, Kamijo Y, Hanazawa T, et al.
Caffeine addiction: Need for awareness and research and regulatory measures.Other primary literatureHumanActiveAsian journal of psychiatry2019
Jain S, Srivastava AS, Verma RP, et al.
Chronic caffeine exposure in adolescence promotes diurnal, biphasic mood-cycling and enhanced motivation for reward in adult mice.Other primary literatureAnimalActiveBehavioural brain research2019
Hinton DJ, Andres-Beck LG, Nett KE, et al.
Abnormal calcium signalling and the caffeine-halothane contracture test.Other primary literatureHumanActiveBritish journal of anaesthesia2019
Figueroa L, Kraeva N, Manno C, et al.
The role of freshwater copepods in the environmental risk assessment of caffeine and propranolol mixtures in the surface water bodies of Spain.Other primary literatureAnimalActiveChemosphere2019
Di Lorenzo T, Castaño-Sánchez A, Di Marzio WD, et al.
Caffeine/Angelica dahurica and caffeine/Salvia miltiorrhiza metabolic inhibition in humans: In vitro and in vivo studies.Other primary literatureHumanActiveComplementary therapies in medicine2019
Sheriffdeen MM, Alehaideb ZI, Law FCP
Techno-economic analysis of caffeine and catechins production from black tea wasteOther primary literatureUnknownUnknownFood and Bioproducts Processing.2019
Sayar NA, Durmaz Şam S, Pinar O, et al.
Pro-oxidant and lifespan extension effects of caffeine and related methylxanthines in Caenorhabditis elegans.Other primary literatureUnknownCorrectedFood chemistry: X2019
Li H, Roxo M, Cheng X, et al.
Caffeine boosts Ataluren's readthrough activity.Other primary literatureUnknownActiveHeliyon2019
Lentini L, Melfi R, Cancemi P, et al.
Review: Trends, Safety, and Recommendations for Caffeine Use in Children and Adolescents.ReviewHumanActiveJournal of the American Academy of Child and Adolescent Psychiatry2019
Temple JL
Rewarding and aversive doses of caffeine alter activity but not conditioned place preference induced by ethanol in DBA/2J mice.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior2019
Zuniga A, Cunningham CL
Efficacy and safety of acetaminophen and caffeine for the management of acute dental pain: A systematic review.ReviewUnknownActiveThe Saudi dental journal2019
Abou-Atme YS, Melis M, Zawawi KH
Serum metabolic profile characteristics of offspring rats before and after birth caused by prenatal caffeine exposure.Other primary literatureAnimalActiveToxicology2019
Chen G, Zhang Q, Ai C, et al.
Glucocorticoid-activation system mediated glucocorticoid-insulin-like growth factor 1 (GC-IGF1) axis programming alteration of adrenal dysfunction induced by prenatal caffeine exposure.Other primary literatureAnimalActiveToxicology letters2019
He Z, Zhang J, Huang H, et al.
Decreased H3K9ac level of KLF4 mediates podocyte developmental toxicity induced by prenatal caffeine exposure in male offspring rats.Other primary literatureAnimalActiveToxicology letters2019
Zhu Y, Chen H, Zhao X, et al.
Oral Administration of Caffeine Exacerbates Cisplatin-Induced Hearing Loss.Other primary literatureAnimalActiveScientific reports2019
Sheth S, Sheehan K, Dhukhwa A, et al.
Gestational caffeine exposure acts as a fetal thyroid-cytokine disruptor by activating caspase-3/BAX/Bcl-2/Cox2/NF-κB at ED 20.Other primary literatureUnknownActiveToxicology research2019
R G A
Recyclable iron(ii) caffeine-derived ionic salt catalyst in the Diels-Alder reaction of cyclopentadiene and α,β-unsaturated N-acyl-oxazolidinones in dimethyl carbonate.Other primary literatureUnknownActiveRSC advances2019
Meng D, Li D, Ollevier T
Caffeine and energy drink use by combat arms soldiers in Afghanistan as a countermeasure for sleep loss and high operational demands.Other primary literatureHumanActiveNutritional neuroscience2019
McLellan TM, Riviere LA, Williams KW, et al.
Caffeine inhibits hypoxia-induced renal fibroblast activation by antioxidant mechanism.Other primary literatureHuman & animalActiveCell adhesion & migration2019
Nilnumkhum A, Kanlaya R, Yoodee S, et al.
Gender Differences in Any-Source Caffeine and Energy Drink Use and Associated Adverse Health Behaviors.Other primary literatureUnknownActiveJournal of caffeine and adenosine research2019
Dillon P, Kelpin S, Kendler K, et al.
Maternal, but not paternal or grandparental, caffeine intake is associated with childhood obesity and adiposity: The Lifeways Cross-Generation Cohort Study.Observational studyHumanActiveThe American journal of clinical nutrition2019
Chen LW, Murrin CM, Mehegan J, et al.
Life-course approaches to investigate adverse effects of caffeine.Other primary literatureHumanActiveThe American journal of clinical nutrition2019
Ley SH
Quantitative myocardial perfusion positron emission tomography and caffeine revisited with new insights on major adverse cardiovascular events and coronary flow capacity.Randomized controlled trialHumanActiveEuropean heart journal. Cardiovascular Imaging2019
Kitkungvan D, Bui L, Johnson NP, et al.
Evening intake of alcohol, caffeine, and nicotine: night-to-night associations with sleep duration and continuity among African Americans in the Jackson Heart Sleep Study.Other primary literatureHumanActiveSleep2019
Spadola CE, Guo N, Johnson DA, et al.
How to recognize caffeine overdose.Other primary literatureHumanActiveNursing2019
Carreon CC, Parsh B
Gender differences in the consumption of alcohol mixed with caffeine and risk of injury.Other primary literatureHumanActiveDrug and alcohol review2019
Roemer A, Stockwell T, Zhao J, et al.
Transepidermal UV radiation of scalp skin ex vivo induces hair follicle damage that is alleviated by the topical treatment with caffeine.Other primary literatureHumanActiveInternational journal of cosmetic science2019
Gherardini J, Wegner J, Chéret J, et al.
Effects of a topical lotion containing aminophylline, caffeine, yohimbe, l-carnitine, and gotu kola on thigh circumference, skinfold thickness, and fat mass in sedentary females.Randomized controlled trialHumanActiveJournal of cosmetic dermatology2019
Escalante G, Bryan P, Rodriguez J
Attempted suicide by caffeine tablet overdose in a 14-year-old girl.Other primary literatureHumanActivePediatrics international : official journal of the Japan Pediatric Society2019
Noto T, Hanazawa T, Yoshizawa T, et al.
Bioassay for Determining the Concentrations of Caffeine and Individual Methylxanthines in Complex Samples.Other primary literatureUnknownActiveApplied and environmental microbiology2019
Gutierrez AE, Shah P, Rex AE, et al.
Posterior Reversible Encephalopathy Syndrome Caused by Fioricet (Butalbital-Acetaminophen-Caffeine).Other primary literatureUnknownActiveCase reports in medicine2019
Cret N, Halalau M, Rezvani S, et al.
Melatonin and Caffeine Supplementation Used, Respectively, as Protective and Stimulating Agents in the Cryopreservation of Human Sperm Improves Survival, Viability, and Motility after Thawing compared to Traditional TEST-Yolk Buffer.Other primary literatureHumanActiveOxidative medicine and cellular longevity2019
Pariz JR, Ranéa C, Monteiro RAC, et al.
Effects of chronic caffeine consumption on sleep and the sleep electroencephalogram in mice.Other primary literatureAnimalActiveJournal of psychopharmacology (Oxford, England)2019
Panagiotou M, Meijer M, Meijer JH, et al.
Caffeine does not affect susceptibility to cortical spreading depolarization in mice.Other primary literatureAnimalActiveJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2019
Yalcin N, Chen SP, Yu ES, et al.
Theophylline and Caffeine as Alternatives During an Aminophylline Shortage.Other primary literatureHumanActiveThe Annals of pharmacotherapy2019
Singleton EL, Le N, Ness GL
Caffeine exposure during pregnancy, small for gestational age birth and neonatal outcome - results from the Norwegian Mother and Child Cohort Study.Other primary literatureHumanActiveBMC pregnancy and childbirth2019
Modzelewska D, Bellocco R, Elfvin A, et al.
Caffeine citrate enhanced cisplatin antitumor effects in osteosarcoma and fibrosarcoma in vitro and in vivo.Other primary literatureHuman & animalActiveBMC cancer2019
Abe K, Yamamoto N, Hayashi K, et al.
Caffeine is associated with improved alveolarization and angiogenesis in male mice following hyperoxia induced lung injury.Other primary literatureAnimalActiveBMC pulmonary medicine2019
Dumpa V, Nielsen L, Wang H, et al.
Antioxidative effects of caffeine in a hyperoxia-based rat model of bronchopulmonary dysplasia.Other primary literatureAnimalActiveRespiratory research2019
Endesfelder S, Strauß E, Scheuer T, et al.
Citrus Aurantium and caffeine complex versus placebo on biomarkers of metabolism: a double blind crossover design.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2019
Kliszczewicz B, Bechke E, Williamson C, et al.
The effects of TeaCrine® and caffeine on endurance and cognitive performance during a simulated match in high-level soccer players.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2019
Bello ML, Walker AJ, McFadden BA, et al.
Effects of acute caffeine, theanine and tyrosine supplementation on mental and physical performance in athletes.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2019
Zaragoza J, Tinsley G, Urbina S, et al.
Tea, coffee, caffeine intake and the risk of cardio-metabolic outcomes: findings from a population with low coffee and high tea consumption.Other primary literatureUnknownActiveNutrition & metabolism2019
Gaeini Z, Bahadoran Z, Mirmiran P, et al.
Comparison of Caffeine versus Theophylline for apnea of prematurity.Other primary literatureUnknownActivePakistan journal of medical sciences2019
Zulqarnain A, Hussain M, Suleri KM, et al.
Electronic device use and beverage related sugar and caffeine intake in US adolescents.Other primary literatureHumanActivePloS one2019
Bradbury KM, Turel O, Morrison KM
Objective sleep assessment in >80,000 UK mid-life adults: Associations with sociodemographic characteristics, physical activity and caffeine.Other primary literatureHumanActivePloS one2019
Zhu G, Catt M, Cassidy S, et al.
Effects of p53 Status of Tumor Cells and Combined Treatment With Mild Hyperthermia, Wortmannin or Caffeine on Recovery From Radiation-Induced Damage.Other primary literatureUnknownActiveWorld journal of oncology2019
Masunaga SI, Tano K, Sanada Y, et al.
The GC-IGF1 axis-mediated testicular dysplasia caused by prenatal caffeine exposure.Other primary literatureAnimalActiveThe Journal of endocrinology2019
Pei LG, Zhang Q, Yuan C, et al.
Amplitude Integrated Electroencephalogram Study of the Effect of Caffeine Citrate on Brain Development in Low Weight Infants with Apnea.Other primary literatureUnknownActiveIranian journal of public health2019
Yang D, Zhou B, Jin B, et al.
Caffeine Therapy in Preterm Infants: The Dose (and Timing) Make the Medicine.ReviewHumanActiveNeonatal network : NN2019
Rostas SE, McPherson C
A randomized, placebo- and active-controlled, multi-country, multi-center parallel group trial to evaluate the efficacy and safety of a fixed-dose combination of 400 mg ibuprofen and 100 mg caffeine compared with ibuprofen 400 mg and placebo in patients with acute lower back or neck pain.Other primary literatureUnknownActiveJournal of pain research2019
Predel HG, Ebel-Bitoun C, Lange R, et al.
Panic Disorder and Chronic Caffeine Use: A Case-control Study.Other primary literatureUnknownActiveClinical practice and epidemiology in mental health : CP & EMH2019
Santos VA, Hoirisch-Clapauch S, Nardi AE, et al.
Combination Effect of Caffeine and Caffeic Acid Treatment on the Oxidant Status of Ectopic Endometrial Cells Separated from Patients with Endometriosis.Other primary literatureUnknownActiveIranian journal of medical sciences2019
Jamali N, Mostafavi-Pour Z, Zal F, et al.
Caffeine and Primary (Migraine) Headaches-Friend or Foe?ReviewUnknownActiveFrontiers in neurology2019
Alstadhaug KB, Andreou AP
Caffeine Ingestion With or Without Low-Dose Carbohydrate Improves Exercise Tolerance in Sedentary Adults.Other primary literatureUnknownActiveFrontiers in nutrition2019
Kumar N, Warren GL, Snow TK, et al.
Effect of a New Synergistic Combination of Low Doses of Acetylsalicylic Acid, Caffeine, Acetaminophen, and Chlorpheniramine in Acute Low Back Pain.Other primary literatureUnknownActiveFrontiers in pharmacology2019
Voicu VA, Mircioiu C, Plesa C, et al.
Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant.Other primary literatureUnknownActiveFrontiers in physiology2019
Rosado C, Tokunaga VK, Sauce R, et al.
Impact of High-Dose Caffeine on the Preterm Ovine Cerebrum and Cerebellum.Other primary literatureUnknownActiveFrontiers in physiology2019
Atik A, De Matteo R, Boomgardt M, et al.
Effect of Caffeine and Other Methylxanthines on Aβ-Homeostasis in SH-SY5Y Cells.Other primary literatureHumanActiveBiomolecules2019
Janitschke D, Nelke C, Lauer AA, et al.
Caffeine and Clinical Outcomes in Premature Neonates.ReviewUnknownActiveChildren (Basel, Switzerland)2019
Kumar VHS, Lipshultz SE
Effects of Caffeine Treatment on Hepatopulmonary Syndrome in Biliary Cirrhotic Rats.Other primary literatureAnimalActiveInternational journal of molecular sciences2019
Chang CC, Chuang CL, Tsai MH, et al.
Caffeine Modulates Cadmium-Induced Oxidative Stress, Neuroinflammation, and Cognitive Impairments by Regulating Nrf-2/HO-1 In Vivo and In Vitro.Other primary literatureUnknownCorrectedJournal of clinical medicine2019
Khan A, Ikram M, Muhammad T, et al.
Room Temperature Synthesis of V-Doped TiO₂ and Its Photocatalytic Activity in the Removal of Caffeine under UV Irradiation.Other primary literatureUnknownActiveMaterials (Basel, Switzerland)2019
Sacco O, Sannino D, Matarangolo M, et al.
Validation of an LC-MS/MS Method for the Quantification of Caffeine and Theobromine Using Non-Matched Matrix Calibration Curve.Other primary literatureHumanActiveMolecules (Basel, Switzerland)2019
Mendes VM, Coelho M, Tomé AR, et al.
The Impact of Caffeine and Coffee on Human Health.Other primary literatureHumanActiveNutrients2019
Cornelis MC
Caffeine Intake During Pregnancy and Neonatal Anthropometric Parameters.Other primary literatureHumanActiveNutrients2019
Wierzejska R, Jarosz M, Wojda B
The Effects of High Peripubertal Caffeine Exposure on the Adrenal Gland in Immature Male and Female Rats.Other primary literatureAnimalActiveNutrients2019
Ryu KY, Roh J
The Acute Effect of Various Doses of Caffeine on Power Output and Velocity during the Bench Press Exercise among Athletes Habitually Using Caffeine.Randomized controlled trialHumanActiveNutrients2019
Wilk M, Filip A, Krzysztofik M, et al.
The Effects of High Doses of Caffeine on Maximal Strength and Muscular Endurance in Athletes Habituated to Caffeine.Randomized controlled trialHumanCorrectedNutrients2019
Wilk M, Krzysztofik M, Filip A, et al.
Impact of Caffeine Intake on 800-m Running Performance and Sleep Quality in Trained Runners.Randomized controlled trialHumanActiveNutrients2019
Ramos-Campo DJ, Pérez A, Ávila-Gandía V, et al.
Caffeine Increased Muscle Endurance Performance Despite Reduced Cortical Activation and Unchanged Neuromuscular Efficiency and Corticomuscular Coherence.Other primary literatureHumanActiveNutrients2019
Franco-Alvarenga PE, Brietzke C, Canestri R, et al.
Effects of Omeprazole and Caffeine Alone and in Combination with Gentamicin and Ciprofloxacin Against Antibiotic Resistant Staphylococcus Aureus and Escherichia Coli Strains.Other primary literatureUnknownActiveJournal of pharmacopuncture2019
Bazzaz BSF, Fakori M, Khameneh B, et al.
Using caffeine on the patients as therapeutic option against treatment-resistant obsessive-compulsive disorder.Other primary literatureUnknownActiveJournal of family medicine and primary care2019
Shams J, Soufi ES, Zahiroddin A, et al.
Effect of caffeine on biomarkers of oxidative stress in lenses of rats with streptozotocin-induced diabetes.Other primary literatureUnknownActiveArchives of medical science : AMS2019
Kaczmarczyk-Sedlak I, Folwarczna J, Sedlak L, et al.
[Clinical effect and safety of different maintenance doses of caffeine citrate in treatment of apnea in very low birth weight preterm infants: a prospective randomized controlled trial].Randomized controlled trialHumanActiveZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2019
Zhang X, Zhang HT, Lyu Y, et al.
Suicides by ingestion of pure caffeine powder. New challenge for public health?Other primary literatureUnknownActiveNeuro endocrinology letters2019
Sidlo J, Sikuta J, Sidlova H, et al.
Caffeine Intoxication in Pregnancy; a case Report.Other primary literatureUnknownActiveArchives of academic emergency medicine2019
Nojima T, Naito H, Kosaki Y, et al.
Association Between Early Caffeine Citrate Administration and Risk of Acute Kidney Injury in Preterm Neonates: Results From the AWAKEN Study.Observational studyHumanCorrectedJAMA pediatrics2018
Harer MW, Askenazi DJ, Boohaker LJ, et al.
Restriction of salt, caffeine and alcohol intake for the treatment of Ménière's disease or syndrome.Systematic reviewHumanActiveThe Cochrane database of systematic reviews2018
Hussain K, Murdin L, Schilder AG
Caffeine for apnea of prematurity and brain development at 11 years of age.Other primary literatureUnknownActiveAnnals of clinical and translational neurology2018
Kelly CE, Ooi WL, Yang JY, et al.
A Prospective Randomized, Double-Blind, Two-Period Crossover Pharmacokinetic Trial Comparing Green Coffee Bean Extract-A Botanically Sourced Caffeine-With a Synthetic USP Control.Randomized controlled trialHumanActiveClinical pharmacology in drug development2018
Morton K, Knight K, Kalman D, et al.
Efficacy and safety of a fixed-dose combination of ibuprofen and caffeine in the management of moderate to severe dental pain after third molar extraction.Randomized controlled trialHumanActiveEuropean journal of pain (London, England)2018
Weiser T, Richter E, Hegewisch A, et al.
[Severe caffeine poisoning with rhabdomyolysis].Other primary literatureHumanActiveDer Anaesthesist2018
Wolter J, Grün D, Otto S
Craving espresso: the dialetics in classifying caffeine as an abuse drug.ReviewHuman & animalActiveNaunyn-Schmiedeberg's archives of pharmacology2018
Dos Santos MKF, Gavioli EC, Rosa LS, et al.
Higher habitual dietary caffeine consumption is related to lower experimental pain sensitivity in a community-based sample.Other primary literatureHumanActivePsychopharmacology2018
Overstreet DS, Penn TM, Cable ST, et al.
Pre-pregnancy caffeine and caffeinated beverage intake and risk of spontaneous abortion.Other primary literatureHumanActiveEuropean journal of nutrition2018
Gaskins AJ, Rich-Edwards JW, Williams PL, et al.
Disagreement between splenic switch-off and myocardial T1-mapping after caffeine intake.Other primary literatureHumanActiveThe international journal of cardiovascular imaging2018
Kuijpers D, van Dijk R, van Assen M, et al.
Coffee extract and caffeine enhance the heat shock response and promote proteostasis in an HSF-1-dependent manner in Caenorhabditis elegans.Other primary literatureAnimalActiveCell stress & chaperones2018
Brunquell J, Morris S, Snyder A, et al.
Neurochemical and Neurotoxic Effects of MDMA (Ecstasy) and Caffeine After Chronic Combined Administration in Mice.Other primary literatureAnimalActiveNeurotoxicity research2018
Górska AM, Kamińska K, Wawrzczak-Bargieła A, et al.
Effects of processing parameters on the caffeine extraction yield during decaffeination of black tea using pilot-scale supercritical carbon dioxide extraction technique.Other primary literatureUnknownActiveJournal of food science and technology2018
Ilgaz S, Ilgaz S, Sat IG, et al.
Administration of Caffeine in Alternate Forms.ReviewHumanActiveSports medicine (Auckland, N.Z.)2018
Wickham KA, Spriet LL
Effect of caffeine on sleep and behaviour in nursing home residents with dementia.Other primary literatureUnknownActiveEuropean geriatric medicine2018
de Pooter-Stijnman LMM, Vrijkotte S, Smalbrugge M
Extra-endothelial TRPV1 channels participate in alcohol and caffeine actions on cerebral artery diameter.Other primary literatureAnimalActiveAlcohol (Fayetteville, N.Y.)2018
North KC, Chang J, Bukiya AN, et al.
Oral caffeine administered during late gestation increases gestation length and piglet temperature in naturally farrowing sows.Other primary literatureAnimalActiveAnimal reproduction science2018
Dearlove BA, Kind KL, Gatford KL, et al.
Caffeine-catalyzed gels.Other primary literatureHuman & animalActiveBiomaterials2018
DiCiccio AM, Lee YL, Glettig DL, et al.
Experimental data on the degradation of caffeine by photo-electro-fenton using BDD electrodes at pilot plant.Other primary literatureUnknownActiveData in brief2018
Lopez-Saavedra N, Muñoz-Delgado LF, Lara-Ramos JA, et al.
Evaluation of caffeine effects on biochemical and genotoxic biomarkers in the neotropical freshwater teleost Prochilodus lineatus.Other primary literatureAnimalActiveEnvironmental toxicology and pharmacology2018
Santos-Silva TG, Montagner CC, Martinez CBR
Review of animal studies on the cardiovascular effects of caffeine.ReviewHuman & animalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2018
Beyer LA, Hixon ML
Caffeine, alcohol, smoking, and reproductive outcomes among couples undergoing assisted reproductive technology treatments.ReviewHumanActiveFertility and sterility2018
Mínguez-Alarcón L, Chavarro JE, Gaskins AJ
Caffeine and oocyte vitrification: Sheep as an animal model.Other primary literatureUnknownActiveInternational journal of veterinary science and medicine2018
Moawad AR, Choi I, Zhu J, et al.
Caffeine Transiently Affects Food Intake at Breakfast.Randomized controlled trialHumanActiveJournal of the Academy of Nutrition and Dietetics2018
Panek-Shirley LM, DeNysschen C, O'Brien E, et al.
Evaluation of a 24-Hour Caffeine Intake Assessment Compared with Urinary Biomarkers of Caffeine Intake among Young Adults in Canada.Other primary literatureHumanActiveJournal of the Academy of Nutrition and Dietetics2018
Vanderlee L, Reid JL, White CM, et al.
Refractory ventricular fibrillation caused by caffeine intoxication.Other primary literatureUnknownActiveJournal of cardiology cases2018
Riku S, Yamamoto T, Kubota Y, et al.
Relationship between aluminum stress and caffeine biosynthesis in suspension cells of Coffea arabica L.Other primary literatureUnknownActiveJournal of inorganic biochemistry2018
Pech-Kú R, Muñoz-Sánchez JA, Monforte-González M, et al.
Detection and determination of undeclared synthetic caffeine in weight loss formulations using HPLC-DAD and UHPLC-MS/MS.Other primary literatureUnknownActiveJournal of pharmaceutical analysis2018
Viana C, Zemolin GM, Dal Molin TR, et al.
Different effects of caffeine on behavioral neurophenotypes of two zebrafish populations.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior2018
Rosa LV, Ardais AP, Costa FV, et al.
Does the presence of caffeine in the marine environment represent an environmental risk? A regional and global study.Other primary literatureUnknownActiveThe Science of the total environment2018
Dafouz R, Cáceres N, Rodríguez-Gil JL, et al.
Cigarette smoke condensate alters Saccharomyces cerevisiae efflux transporter mRNA and activity and increases caffeine toxicity.Other primary literatureUnknownActiveToxicology2018
Sayyed K, Le Vée M, Chamieh H, et al.
The clinical toxicology of caffeine: A review and case study.ReviewUnknownActiveToxicology reports2018
Willson C
Development and initial psychometric validation of the Brief-Caffeine Expectancy Questionnaire (B-CaffEQ).Other primary literatureHumanActivePsychological assessment2018
Kearns NT, Blumenthal H, Natesan P, et al.
Reinforcing Effects of Binary Mixtures of Common Bath Salt Constituents: Studies with 3,4-Methylenedioxypyrovalerone (MDPV), 3,4-Methylenedioxymethcathinone (methylone), and Caffeine in Rats.Other primary literatureAnimalActiveNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2018
Gannon BM, Galindo KI, Mesmin MP, et al.
Caffeine: an evidence-based success story in VLBW pharmacotherapy.ReviewHumanActivePediatric research2018
Dobson NR, Hunt CE
Caffeine-inducible gene switches controlling experimental diabetes.Other primary literatureHuman & animalActiveNature communications2018
Bojar D, Scheller L, Hamri GC, et al.
Caffeine Augments Anesthesia Neurotoxicity in the Fetal Macaque Brain.Other primary literatureAnimalActiveScientific reports2018
Noguchi KK, Johnson SA, Manzella FM, et al.
Association between Caffeine Consumption in Pregnancy and Low Birth Weight and Preterm Birth in the birth Cohort of Ribeirão Preto.Other primary literatureHumanActiveRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2018
Vitti FP, Grandi C, Cavalli RC, et al.
Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson's disease and DLB.Other primary literatureAnimalActiveProceedings of the National Academy of Sciences of the United States of America2018
Yan R, Zhang J, Park HJ, et al.
Extracorporeal elimination of butalbital in acute aspirin-butalbital-caffeine-codeine (Fiorinal with Codeine) poisoning.Other primary literatureHumanActiveClinical toxicology (Philadelphia, Pa.)2018
Poyant JO, Albright R, Clain J, et al.
The complete chloroplast genome sequence of Camellia ptilophylla (Theaceae): a natural caffeine-free tea plant endemic to China.Other primary literatureUnknownActiveMitochondrial DNA. Part B, Resources2018
Li W, Xing F, Ng WL, et al.
Caffeine Intake and Its Association with Body Composition Measures and Macronutrient Intakes in People Living with HIV in the Miami Adult Studies on HIV Cohort.Other primary literatureUnknownActiveJournal of caffeine and adenosine research2018
Ramamoorthy V, Campa A, Rubens M, et al.
Caffeine Treatment for Apnea of Prematurity and the Influence on Dose-Dependent Postnatal Weight Gain Observed Over 15 Years.Other primary literatureUnknownActiveJournal of caffeine and adenosine research2018
Philip RK, Ismail A, Murphy B, et al.
Associations of maternal caffeine intake with birth outcomes: results from the Lifeways Cross Generation Cohort Study.Other primary literatureHumanActiveThe American journal of clinical nutrition2018
Chen LW, Fitzgerald R, Murrin CM, et al.
Caffeine consumption during early pregnancy impairs oviductal embryo transport, embryonic development and uterine receptivity in mice.Other primary literatureAnimalActiveBiology of reproduction2018
Qian J, Zhang Y, Qu Y, et al.
Determination of Acetaminophen, Dexchlorpheniramine, Caffeine, Cotinine and Salicylic acid in 100 μL of Whole Blood by UHPLC-MS/MS.Other primary literatureHumanActiveJournal of analytical toxicology2018
Krpo M, Arnestad M, Karinen R
Severe Sympathomimetic Toxidrome in a French Soldier: How Caffeine Overdose Can Lead to Severe Consequences.Other primary literatureHumanActiveMilitary medicine2018
Laitselart P, Saguin E, Plantamura J, et al.
Caffeine Accelerates Emergence from Isoflurane Anesthesia in Humans: A Randomized, Double-blind, Crossover Study.Randomized controlled trialHumanActiveAnesthesiology2018
Fong R, Wang L, Zacny JP, et al.
Caffeine Sodium Benzoate for Electroconvulsive Therapy Augmentation.Other primary literatureHumanActiveThe journal of ECT2018
Bozymski KM, Potter TG, Venkatachalam V, et al.
Does early exposure to caffeine promote smoking and alcohol use behavior? A prospective analysis of middle school students.Other primary literatureUnknownActiveAddiction (Abingdon, England)2018
Kristjansson AL, Kogan SM, Mann MJ, et al.
Effects of Caffeine on Countermovement-Jump Performance Variables in Elite Male Volleyball Players.Randomized controlled trialHumanActiveInternational journal of sports physiology and performance2018
Zbinden-Foncea H, Rada I, Gomez J, et al.
Dangerous mistake: an accidental caffeine overdose.Other primary literatureHumanActiveBMJ case reports2018
Andrade A, Sousa C, Pedro M, et al.
Maternal caffeine intake during pregnancy and childhood growth and overweight: results from a large Norwegian prospective observational cohort study.Observational studyHumanActiveBMJ open2018
Papadopoulou E, Botton J, Brantsæter AL, et al.
Screen time behaviours and caffeine intake in US children: findings from the cross-sectional National Health and Nutrition Examination Survey (NHANES).Other primary literatureUnknownActiveBMJ paediatrics open2018
Ahluwalia N, Frenk SM, Quan SF
Method Development for Assessing Carbamazepine, Caffeine, and Atrazine in Water Sources from the Brazilian Federal District Using UPLC-QTOF/MS.Other primary literatureUnknownActiveInternational journal of analytical chemistry2018
Sodré FF, Cavalcanti CMP
Caffeine Sensitizes U87-MG Human Glioblastoma Cells to Temozolomide through Mitotic Catastrophe by Impeding G2 Arrest.Other primary literatureHumanActiveBioMed research international2018
Li N, Zhang P, Kiang KMY, et al.
Efficacy and Safety of Different Maintenance Doses of Caffeine Citrate for Treatment of Apnea in Premature Infants: A Systematic Review and Meta-Analysis.Meta-analysisHumanActiveBioMed research international2018
Chen J, Jin L, Chen X
Effects of adolescent caffeine consumption on cocaine self-administration and reinstatement of cocaine seeking.Other primary literatureUnknownActiveJournal of psychopharmacology (Oxford, England)2018
Larson TA, O'Neill CE, Palumbo MP, et al.
Phenotyping of CYP 4501A2 Activity by Total Overnight Salivary Caffeine Assessment (TOSCA) in Patients on Warfarin Treatment: A Cross-Sectional Study.Other primary literatureHumanActiveClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis2018
Tarantino G, Capone D, Contaldi P, et al.
Caffeine is a risk factor for osteopenia of prematurity in preterm infants: a cohort study.Other primary literatureHumanActiveBMC pediatrics2018
Ali E, Rockman-Greenberg C, Moffatt M, et al.
The influence of citrus aurantium and caffeine complex versus placebo on the cardiac autonomic response: a double blind crossover design.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2018
Kliszczewicz B, Bechke E, Williamson C, et al.
[Comparative Study of the Efficacy and Safety of Caffeine and Aminophylline for the Treatment of Apnea in Preterm Infants].Other primary literatureHumanActiveYakugaku zasshi : Journal of the Pharmaceutical Society of Japan2018
Nagasato A, Nakamura M, Kamimura H
Dopamine synergizes with caffeine to increase the heart rate of Daphnia.Other primary literatureUnknownActiveF1000Research2018
Kundu A, Singh G
Caffeine Toxicity Following Ingestion of an Exercise Supplement by a Patient with Type 1 Diabetes.Other primary literatureUnknownActiveEuropean journal of case reports in internal medicine2018
Hamed E
CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine.Other primary literatureHuman & animalActivePLoS biology2018
Ale-Agha N, Goy C, Jakobs P, et al.
Haemodynamic effects of prenatal caffeine on the cardiovascular transition in ventilated preterm lambs.Other primary literatureAnimalActivePloS one2018
Binder-Heschl C, Crossley K, Te Pas A, et al.
Effect of single caffeine intake on neuropsychological functions in healthy volunteers: A double-blind placebo-controlled study.Randomized controlled trialHumanActivePloS one2018
Konishi Y, Hori H, Ide K, et al.
[Caffeine: traditional and new therapeutic indications and use as a dermatological model drug].ReviewHumanActiveOrvosi hetilap2018
Bors L, Bajza Á, Kocsis D, et al.
Effects of caffeine administration on sedation and respiratory parameters in patients recovering from anesthesia.Other primary literatureHumanActiveBosnian journal of basic medical sciences2018
Warner NS, Warner MA, Schroeder DR, et al.
Comparing time-series of chemical concentrations in zebrafish (Danio rerio) embryos/larvae exposed to teratogens with different hydrophobicity; caffeine, sodium valproate, and diethylstilbestrol.Other primary literatureAnimalActiveThe Journal of toxicological sciences2018
Nawaji T, Mizoguchi N, Ono M, et al.
Virtual Screening and Statistical Analysis in the Design of New Caffeine Analogues Molecules with Potential Epithelial Anticancer Activity.Other primary literatureHuman & animalActiveCurrent pharmaceutical design2018
da Silva Costa J, da Silva Lopes Costa K, Cruz JV, et al.
The efficacy and safety of two different doses of caffeine in respiratory function of preterm infants.Other primary literatureUnknownActiveCaspian journal of internal medicine2018
Faramarzi F, Shiran M, Rafati M, et al.
Health Related Nutritional Knowledge and Dietary Behavior Regarding Caffeine Intake among High School Students in Yongin Region.Other primary literatureUnknownActiveOsong public health and research perspectives2018
Kim SY
Caffeine induces metformin anticancer effect on fibrosarcoma in hamsters.Other primary literatureAnimalActiveEuropean review for medical and pharmacological sciences2018
Popović DJ, Lalošević D, Miljković D, et al.
Hemodynamic Effects on Systemic Blood Flow and Ductal Shunting Flow after Loading Dose of Intravenous Caffeine in Preterm Infants according to the Patency of Ductus Arteriosus.Other primary literatureHumanActiveJournal of Korean medical science2018
Hwang J, Kim YS, Shin JH, et al.
Caffeine Protects Dopaminergic Neurons From Dopamine-Induced Neurodegeneration via Synergistic Adenosine-Dopamine D2-Like Receptor Interactions in Transgenic Caenorhabditis elegans.Other primary literatureUnknownActiveFrontiers in neuroscience2018
Manalo RVM, Medina PMB
Chronic Caffeine Treatment Protects Against α-Synucleinopathy by Reestablishing Autophagy Activity in the Mouse Striatum.Other primary literatureUnknownActiveFrontiers in neuroscience2018
Luan Y, Ren X, Zheng W, et al.
The Impact of Coffee and Caffeine on Multiple Sclerosis Compared to Other Neurodegenerative Diseases.Other primary literatureUnknownActiveFrontiers in nutrition2018
Herden L, Weissert R
Long-term Treatment with Low-Dose Caffeine Worsens BPSD-Like Profile in 3xTg-AD Mice Model of Alzheimer's Disease and Affects Mice with Normal Aging.Other primary literatureUnknownActiveFrontiers in pharmacology2018
Baeta-Corral R, Johansson B, Giménez-Llort L
Prevalence Estimates for Pharmacological Neuroenhancement in Austrian University Students: Its Relation to Health-Related Risk Attitude and the Framing Effect of Caffeine Tablets.Other primary literatureUnknownActiveFrontiers in pharmacology2018
Dietz P, Iberl B, Schuett E, et al.
Acute Administration of Caffeine: The Effect on Motor Coordination, Higher Brain Cognitive Functions, and the Social Behavior of BLC57 Mice.Other primary literatureUnknownActiveBehavioral sciences (Basel, Switzerland)2018
Almosawi S, Baksh H, Qareeballa A, et al.
Evaluation of Caffeine Consumption among Pregnant Women from Southern Poland.Other primary literatureHumanActiveInternational journal of environmental research and public health2018
Błaszczyk-Bębenek E, Piórecka B, Kopytko M, et al.
New Insights on the Photodegradation of Caffeine in the Presence of Bio-Based Substances-Magnetic Iron Oxide Hybrid Nanomaterials.Other primary literatureUnknownActiveMaterials (Basel, Switzerland)2018
Palma D, Bianco Prevot A, Brigante M, et al.
The Effects of Carbohydrates, in Isolation and Combined with Caffeine, on Cognitive Performance and Mood-Current Evidence and Future Directions.ReviewHuman & animalActiveNutrients2018
Bernard BN, Louise LC, Louise D
Adherence to the Caffeine Intake Guideline during Pregnancy and Birth Outcomes: A Prospective Cohort Study.Other primary literatureHumanActiveNutrients2018
Peacock A, Hutchinson D, Wilson J, et al.
Caffeine-Related Deaths: Manner of Deaths and Categories at Risk.Systematic reviewHumanActiveNutrients2018
Cappelletti S, Piacentino D, Fineschi V, et al.
Maternal and Paternal Caffeine Intake and ART Outcomes in Couples Referring to an Italian Fertility Clinic: A Prospective Cohort.Other primary literatureHumanActiveNutrients2018
Ricci E, Noli S, Cipriani S, et al.
Mendelian Randomization Studies of Coffee and Caffeine Consumption.ReviewHumanActiveNutrients2018
Cornelis MC, Munafo MR
Key Findings and Implications of a Recent Systematic Review of the Potential Adverse Effects of Caffeine Consumption in Healthy Adults, Pregnant Women, Adolescents, and Children.Other primary literatureHumanActiveNutrients2018
Doepker C, Franke K, Myers E, et al.
Caffeine in the Diet: Country-Level Consumption and Guidelines.ReviewHumanActiveNutrients2018
Reyes CM, Cornelis MC
Taste Perception and Caffeine Consumption: An fMRI Study.Other primary literatureHumanActiveNutrients2018
Gramling L, Kapoulea E, Murphy C
Pharmacokinetics and Pharmacodynamics of (S)-Ketoprofen Co-Administered with Caffeine: A Preclinical Study in Arthritic Rats.Other primary literatureUnknownActivePharmaceutics2018
Medina-López R, Vara-Gama N, Soria-Arteche O, et al.
Coffee Consumption and Prevention of Cirrhosis: In Support of the Caffeine Hypothesis.ReviewHuman & animalActiveGene expression2018
Dranoff JA
Experimental Protocol for Examining Behavioral Response Profiles in Larval Fish: Application to the Neuro-stimulant Caffeine.Other primary literatureAnimalActiveJournal of visualized experiments : JoVE2018
Steele WB, Mole RA, Brooks BW
Caffeine Extraction, Enzymatic Activity and Gene Expression of Caffeine Synthase from Plant Cell Suspensions.Other primary literatureUnknownActiveJournal of visualized experiments : JoVE2018
Pech-Kú R, Muñoz-Sánchez JA, Monforte-González M, et al.
Evodiamine Reduces Caffeine-Induced Sleep Disturbances and Excitation in Mice.Other primary literatureUnknownActiveBiomolecules & therapeutics2018
Ko YH, Shim KY, Lee SY, et al.
Method Development and Validation for the Determination of Caffeine: An Alkaloid from Coffea arabica by High-performance Liquid Chromatography Method.Other primary literatureUnknownActivePharmacognosy research2018
Naveen P, Lingaraju HB, Deepak M, et al.
Two combined amino acids promote sleep activity in caffeine-induced sleepless model systems.Other primary literatureUnknownActiveNutrition research and practice2018
Hong KB, Park Y, Suh HJ
In vitro evaluation of antibacterial activity of verbascoside, lemon verbena extract and caffeine in combination with gentamicin against drug-resistant Staphylococcus aureus and Escherichia coli clinical isolates.Other primary literatureUnknownActiveAvicenna journal of phytomedicine2018
Fazly Bazzaz BS, Khameneh B, Zahedian Ostad MR, et al.
Taurine, caffeine, and energy drinks: Reviewing the risks to the adolescent brain.ReviewHumanActiveBirth defects research2017
Curran CP, Marczinski CA
Measurement of caffeine and its three primary metabolites in human plasma by HPLC-ESI-MS/MS and clinical application.Other primary literatureHumanActiveBiomedical chromatography : BMC2017
Chen F, Hu ZY, Parker RB, et al.
Pharmacokinetic Effects of Isavuconazole Coadministration With the Cytochrome P450 Enzyme Substrates Bupropion, Repaglinide, Caffeine, Dextromethorphan, and Methadone in Healthy Subjects.Other primary literatureHumanActiveClinical pharmacology in drug development2017
Yamazaki T, Desai A, Goldwater R, et al.
Multiscale modeling reveals inhibitory and stimulatory effects of caffeine on acetaminophen-induced toxicity in humans.Other primary literatureHumanActiveCPT: pharmacometrics & systems pharmacology2017
Thiel C, Cordes H, Baier V, et al.
Effects of caffeine on alcohol reinforcement: beverage choice, self-administration, and subjective ratings.Other primary literatureHumanActivePsychopharmacology2017
Sweeney MM, Meredith SE, Evatt DP, et al.
Development of a Two-Dimensional Model for Predicting Transdermal Permeation with the Follicular Pathway: Demonstration with a Caffeine Study.Other primary literatureHumanActivePharmaceutical research2017
Kattou P, Lian G, Glavin S, et al.
Nonfatal and fatal intoxications with pure caffeine - report of three different cases.Other primary literatureHumanActiveForensic science, medicine, and pathology2017
Magdalan J, Zawadzki M, Skowronek R, et al.
Assessment of Pharmacokinetic Interactions Between Obeticholic Acid and Caffeine, Midazolam, Warfarin, Dextromethorphan, Omeprazole, Rosuvastatin, and Digoxin in Phase 1 Studies in Healthy Subjects.Other primary literatureHumanActiveAdvances in therapy2017
Edwards JE, Eliot L, Parkinson A, et al.
Aminophylline and caffeine for reversal of adverse symptoms associated with regadenoson SPECT MPI.Randomized controlled trialHumanRetractedJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017
Doran JA, Sajjad W, Schneider MD, et al.
Intravenous caffeine: An alternative to aminophylline to reverse adverse effects during regadenoson myocardial perfusion imaging.Other primary literatureUnknownActiveJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017
Jolly AF, Thomas GS
Caffeine Protects Against Anticonvulsant-Induced Neurotoxicity in the Developing Rat Brain.Other primary literatureAnimalActiveNeurotoxicity research2017
Endesfelder S, Weichelt U, Schiller C, et al.
Comparative Efficacy and Safety of Caffeine and Aminophylline for Apnea of Prematurity in Preterm (≤34 weeks) Neonates: A Randomized Controlled Trial.Randomized controlled trialHumanActiveIndian pediatrics2017
Shivakumar M, Jayashree P, Najih M, et al.
Associations of Coffee, Tea, and Caffeine Intake with Coronary Artery Calcification and Cardiovascular Events.Other primary literatureHumanActiveThe American journal of medicine2017
Miller PE, Zhao D, Frazier-Wood AC, et al.
Caffeine - rich infusion from Cola nitida (kola nut) inhibits major carbohydrate catabolic enzymes; abates redox imbalance; and modulates oxidative dysregulated metabolic pathways and metabolites in Fe2+-induced hepatic toxicity.Other primary literatureAnimalActiveBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2017
Erukainure OL, Oyebode OA, Sokhela MK, et al.
Interaction among hERG channel blockers is a potential mechanism of death in caffeine overdose.Other primary literatureHuman & animalActiveEuropean journal of pharmacology2017
Zheng J, Zhao W, Xu K, et al.
Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children.Systematic reviewHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2017
Wikoff D, Welsh BT, Henderson R, et al.
Creating functional nanostructures: Encapsulation of caffeine into α-lactalbumin nanotubesOther primary literatureUnknownUnknownInnovative Food Science and Emerging Technologies.2017
Fuciños C, Fuciños C, Míguez M, et al.
Caffeine and Insomnia in People Living With HIV From the Miami Adult Studies on HIV (MASH) Cohort.Other primary literatureHumanActiveThe Journal of the Association of Nurses in AIDS Care : JANAC2017
Ramamoorthy V, Campa A, Rubens M, et al.
Beneficial effects of oral pure caffeine on oxidative stress.Other primary literatureUnknownActiveJournal of clinical & translational endocrinology2017
Metro D, Cernaro V, Santoro D, et al.
Early Caffeine Prophylaxis and Risk of Failure of Initial Continuous Positive Airway Pressure in Very Low Birth Weight Infants.Observational studyHumanActiveThe Journal of pediatrics2017
Patel RM, Zimmerman K, Carlton DP, et al.
Evidence of the Impact of Diet, Fluid Intake, Caffeine, Alcohol and Tobacco on Lower Urinary Tract Symptoms: A Systematic Review.Systematic reviewHumanActiveThe Journal of urology2017
Bradley CS, Erickson BA, Messersmith EE, et al.
[Combination of hemodialysis and hemofiltration in severe caffeine intoxication].Other primary literatureHumanActiveNephrologie & therapeutique2017
Colin-Benoit E, Friolet R, Rusca M, et al.
Caffeine for apnea of prematurity: Effects on the developing brain.ReviewHuman & animalActiveNeurotoxicology2017
Atik A, Harding R, De Matteo R, et al.
Mapping the pharmacological modulation of brain oxygen metabolism: The effects of caffeine on absolute CMRO<sub>2</sub> measured using dual calibrated fMRI.Randomized controlled trialHumanActiveNeuroImage2017
Merola A, Germuska MA, Warnert EA, et al.
In vivo assessment of hair cell damage and developmental toxicity caused by gestational caffeine exposure using zebrafish (Danio rerio) models.Other primary literatureAnimalActiveNeurotoxicology and teratology2017
Rah YC, Yoo MH, Choi J, et al.
Caffeine citrate - Is it a silver bullet in neonatology?ReviewHumanActivePediatrics and neonatology2017
Shrestha B, Jawa G
The margin of internal exposure (MOIE) concept for dermal risk assessment based on oral toxicity data - A case study with caffeine.Other primary literatureHuman & animalActiveToxicology2017
Bessems JGM, Paini A, Gajewska M, et al.
Caffeine and cardiovascular health.ReviewHumanActiveRegulatory toxicology and pharmacology : RTP2017
Turnbull D, Rodricks JV, Mariano GF, et al.
Energy drinks available in Ireland: a description of caffeine and sugar content.Other primary literatureUnknownActivePublic health nutrition2017
Keaver L, Gilpin S, Fernandes da Silva JC, et al.
A daily diary examination of caffeine mixed with alcohol among college students.Other primary literatureHumanActiveHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2017
Linden-Carmichael AN, Lau-Barraco C
Glucocorticoid mediates prenatal caffeine exposure-induced endochondral ossification retardation and its molecular mechanism in female fetal rats.Other primary literatureAnimalActiveCell death & disease2017
Shangguan Y, Jiang H, Pan Z, et al.
Long-term consumption of caffeine-free high sucrose cola beverages aggravates the pathogenesis of EAE in mice.Other primary literatureUnknownActiveCell discovery2017
Cao G, Wang Q, Huang W, et al.
Caffeine inhibits hypothalamic A1R to excite oxytocin neuron and ameliorate dietary obesity in mice.Other primary literatureHuman & animalActiveNature communications2017
Wu L, Meng J, Shen Q, et al.
Caffeine ameliorates hyperoxia-induced lung injury by protecting GCH1 function in neonatal rat pups.Other primary literatureAnimalActivePediatric research2017
Jing X, Huang YW, Jarzembowski J, et al.
Presence of caffeine reversibly interferes with efficacy of acupuncture-induced analgesia.Other primary literatureAnimalActiveScientific reports2017
Fujita T, Feng C, Takano T
Effect of Genetic Information and Information About Caffeine Content on Caffeine Withdrawal Symptoms.Other primary literatureHumanActiveScientific reports2017
Mills L, Dar-Nimrod I, Colagiuri B
Maternal Glucocorticoid Elevation and Associated Fetal Thymocyte Apoptosis are Involved in Immune Disorders of Prenatal Caffeine Exposed Offspring Mice.Other primary literatureAnimalActiveScientific reports2017
Liu HX, Chen T, Wen X, et al.
High-fat diet and chronic stress aggravate adrenal function abnormality induced by prenatal caffeine exposure in male offspring rats.Other primary literatureAnimalActiveScientific reports2017
He Z, Lv F, Ding Y, et al.
Genotoxicity of antiobesity drug orlistat and effect of caffeine intervention: an in vitro study.Other primary literatureHumanActiveDrug and chemical toxicology2017
Chakrabarti M, Ghosh I, Jana A, et al.
Caffeine combined with sedative/anesthetic drugs triggers widespread neuroapoptosis in a mouse model of prematurity.Other primary literatureHuman & animalActiveThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians2017
Cabrera OH, O'Connor SD, Swiney BS, et al.
Modulation of chemotherapy-induced cytotoxicity in SH-SY5Y neuroblastoma cells by caffeine and chlorogenic acid.Other primary literatureHumanActiveToxicology mechanisms and methods2017
Hall S, Anoopkumar-Dukie S, Grant GD, et al.
The Taste of Caffeine.ReviewUnknownActiveJournal of caffeine research2017
Poole RL, Tordoff MG
Impact of Caffeine Boluses and Caffeine Discontinuation on Apnea and Hypoxemia in Preterm Infants.Other primary literatureUnknownActiveJournal of caffeine research2017
Tabacaru CR, Jang SY, Patel M, et al.
Assessment of the Drug-Drug Interaction Potential Between Theacrine and Caffeine in Humans.Other primary literatureUnknownActiveJournal of caffeine research2017
He H, Ma D, Crone LB, et al.
A Randomized, Two-Way Crossover Study to Evaluate the Pharmacokinetics of Caffeine Delivered Using Caffeinated Chewing Gum Versus a Marketed Caffeinated Beverage in Healthy Adult Volunteers.Other primary literatureUnknownActiveJournal of caffeine research2017
Sadek P, Pan X, Shepherd P, et al.
The Relationship Between Caffeine Intake and Immunological and Virological Markers of HIV Disease Progression in Miami Adult Studies on HIV Cohort.Other primary literatureHumanActiveViral immunology2017
Ramamoorthy V, Campa A, Rubens M, et al.
The association between pre-treatment maternal alcohol and caffeine intake and outcomes of assisted reproduction in a prospectively followed cohort.Other primary literatureHumanActiveHuman reproduction (Oxford, England)2017
Abadia L, Chiu YH, Williams PL, et al.
Review of Caffeine-Related Fatalities along with Postmortem Blood Concentrations in 51 Poisoning Deaths.ReviewHumanActiveJournal of analytical toxicology2017
Jones AW
Caffeine Concentrations in Coffee, Tea, Chocolate, and Energy Drink Flavored E-liquids.Other primary literatureUnknownActiveNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2017
Lisko JG, Lee GE, Kimbrell JB, et al.
Nutrition Influences Caffeine-Mediated Sleep Loss in Drosophila.Other primary literatureAnimalActiveSleep2017
Keebaugh ES, Park JH, Su C, et al.
Caffeine preferentially protects against oxygen-induced retinopathy.Other primary literatureAnimalActiveFASEB journal : official publication of the Federation of American Societies for Experimental Biology2017
Zhang S, Zhou R, Li B, et al.
Systematic review and meta-analysis of clinical outcomes of early caffeine therapy in preterm neonates.Meta-analysisHumanCorrectedBritish journal of clinical pharmacology2017
Kua KP, Lee SW
Comparison of caffeine disposition following administration by oral solution (energy drink) and inspired powder (AeroShot) in human subjects.Other primary literatureHumanActiveBritish journal of clinical pharmacology2017
Laizure SC, Meibohm B, Nelson K, et al.
The neuroprotective effects of caffeine in neurodegenerative diseases.ReviewHuman & animalActiveCNS neuroscience & therapeutics2017
Kolahdouzan M, Hamadeh MJ
Cross-sectional surveys of the amount of sugar, energy and caffeine in sugar-sweetened drinks marketed and consumed as energy drinks in the UK between 2015 and 2017: monitoring reformulation progress.Other primary literatureHumanActiveBMJ open2017
Hashem KM, He FJ, MacGregor GA
Caffeine protects against experimental acute pancreatitis by inhibition of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release.Other primary literatureAnimalActiveGut2017
Huang W, Cane MC, Mukherjee R, et al.
Having a Coffee Break: The Impact of Caffeine Consumption on Microglia-Mediated Inflammation in Neurodegenerative Diseases.ReviewHuman & animalActiveMediators of inflammation2017
Madeira MH, Boia R, Ambrósio AF, et al.
An Open-Label Randomized Multicenter Study Assessing the Noninferiority of a Caffeine-Based Topical Liquid 0.2% versus Minoxidil 5% Solution in Male Androgenetic Alopecia.Randomized controlled trialHumanActiveSkin pharmacology and physiology2017
Dhurat R, Chitallia J, May TW, et al.
Randomized Controlled Trial of High-Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters.Randomized controlled trialHumanActiveJournal of the American Heart Association2017
Fletcher EA, Lacey CS, Aaron M, et al.
Caffeine intake decreases oxidative stress and inflammatory biomarkers in experimental liver diseases induced by thioacetamide: Biochemical and histological study.Other primary literatureAnimalActiveInternational journal of immunopathology and pharmacology2017
Amer MG, Mazen NF, Mohamed AM
Sleep Deprivation Impairs and Caffeine Enhances My Performance, but Not Always Our Performance.Other primary literatureHumanActivePersonality and social psychology review : an official journal of the Society for Personality and Social Psychology, Inc2017
Faber NS, Häusser JA, Kerr NL
Caffeine in the management of patients with headache.ReviewHumanActiveThe journal of headache and pain2017
Lipton RB, Diener HC, Robbins MS, et al.
In-vitro examination of the positive inotropic effect of caffeine and taurine, the two most frequent active ingredients of energy drinks.Other primary literatureHumanCorrectedBMC cardiovascular disorders2017
Chaban R, Kornberger A, Branski N, et al.
Caffeine modulates glucocorticoid-induced expression of CTGF in lung epithelial cells and fibroblasts.Other primary literatureHumanActiveRespiratory research2017
Fehrholz M, Glaser K, Speer CP, et al.
Coffee and caffeine intake and male infertility: a systematic review.Systematic reviewHumanActiveNutrition journal2017
Ricci E, Viganò P, Cipriani S, et al.
Effects of caffeine on the detection of ischemia in patients undergoing adenosine stress cardiovascular magnetic resonance imaging.Other primary literatureHumanActiveJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2017
Greulich S, Kaesemann P, Seitz A, et al.
Suicide by ingestion of caffeine.Other primary literatureUnknownActiveEgyptian journal of forensic sciences2017
Aknouche F, Guibert E, Tessier A, et al.
Caffeine as symptomatic treatment for Parkinson disease (Café-PD): A randomized trial.Randomized controlled trialHumanActiveNeurology2017
Postuma RB, Anang J, Pelletier A, et al.
Caffsim: simulation of plasma caffeine concentrations implemented as an R package and Web-applications.Other primary literatureUnknownActiveTranslational and clinical pharmacology2017
Han S, Cho YS, Yoon SK, et al.
Single Dose Caffeine Protects the Neonatal Mouse Brain against Hypoxia Ischemia.Other primary literatureHuman & animalActivePloS one2017
Winerdal M, Urmaliya V, Winerdal ME, et al.
Behavioral and pathophysiological outcomes associated with caffeine consumption and repetitive mild traumatic brain injury (RmTBI) in adolescent rats.Other primary literatureAnimalActivePloS one2017
Yamakawa GR, Lengkeek C, Salberg S, et al.
Sleep Deprivation and Caffeine Treatment Potentiate Photic Resetting of the Master Circadian Clock in a Diurnal Rodent.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2017
Jha PK, Bouâouda H, Gourmelen S, et al.
Dose- and time-related effects of caffeine on the testis in immature male rats.Other primary literatureAnimalActiveExperimental animals2017
Bae J, Choi H, Choi Y, et al.
In vitro pharmacological interaction of caffeine and first-line antibiotics is antagonistic against clinically important bacterial pathogens.Other primary literatureHumanActiveActa biochimica Polonica2017
Olajuyigbe OO, Adeoye-Isijola MO, Okon V, et al.
Association between coffee or caffeine consumption and fecundity and fertility: a systematic review and dose-response meta-analysis.ReviewUnknownActiveClinical epidemiology2017
Lyngsø J, Ramlau-Hansen CH, Bay B, et al.
Caffeine as an opioid analgesic adjuvant in fibromyalgia.Other primary literatureUnknownActiveJournal of pain research2017
Scott JR, Hassett AL, Brummett CM, et al.
The effect of caffeine on orthodontic tooth movement in rats.Other primary literatureUnknownActiveIranian journal of basic medical sciences2017
Shirazi M, Vaziri H, Salari B, et al.
Ingestion of green tea with lowered caffeine improves sleep quality of the elderly via suppression of stress.Other primary literatureUnknownActiveJournal of clinical biochemistry and nutrition2017
Unno K, Noda S, Kawasaki Y, et al.
Intravenous caffeine citrate vs. magnesium sulfate for reducing pain in patients with acute migraine headache; a prospective quasi-experimental study.Other primary literatureUnknownActiveThe Korean journal of pain2017
Baratloo A, Mirbaha S, Delavar Kasmaei H, et al.
Cocaine and Caffeine Effects on the Conditioned Place Preference Test: Concomitant Changes on Early Genes within the Mouse Prefrontal Cortex and Nucleus Accumbens.Other primary literatureUnknownActiveFrontiers in behavioral neuroscience2017
Muñiz JA, Prieto JP, González B, et al.
Chlorpheniramine Potentiates the Analgesic Effect in Migraine of Usual Caffeine, Acetaminophen, and Acetylsalicylic Acid Combination.Other primary literatureUnknownActiveFrontiers in pharmacology2017
Voicu VA, Mircioiu I, Sandulovici R, et al.
The Safety of Ingested Caffeine: A Comprehensive Review.ReviewUnknownActiveFrontiers in psychiatry2017
Temple JL, Bernard C, Lipshultz SE, et al.
Synthesis and Characterization of a New Bivalent Ligand Combining Caffeine and Docosahexaenoic Acid.Other primary literatureHumanActiveMolecules (Basel, Switzerland)2017
Fernández-Dueñas V, Azuaje J, Morató X, et al.
CYP1A2 Genotype Variations Do Not Modify the Benefits and Drawbacks of Caffeine during Exercise: A Pilot Study.Randomized controlled trialHumanActiveNutrients2017
Salinero JJ, Lara B, Ruiz-Vicente D, et al.
Cognitive Performance Enhancement Induced by Caffeine, Carbohydrate and Guarana Mouth Rinsing during Submaximal Exercise.Randomized controlled trialHumanActiveNutrients2017
Pomportes L, Brisswalter J, Casini L, et al.
Caffeine Improves Basketball Performance in Experienced Basketball Players.Randomized controlled trialHumanActiveNutrients2017
Puente C, Abián-Vicén J, Salinero JJ, et al.
Caffeine at a Moderate Dose Did Not Affect the Skeletal System of Rats with Streptozotocin-Induced Diabetes.Other primary literatureAnimalActiveNutrients2017
Folwarczna J, Janas A, Cegieła U, et al.
Glutamate‑mediated effects of caffeine and interferon‑γ on mercury-induced toxicity.Other primary literatureHumanActiveInternational journal of molecular medicine2017
Engin AB, Engin ED, Golokhvast K, et al.
Caffeine induces sustained apoptosis of human gastric cancer cells by activating the caspase‑9/caspase‑3 signalling pathway.Other primary literatureHumanActiveMolecular medicine reports2017
Liu H, Zhou Y, Tang L
Caffeine Increases Apolipoprotein A-1 and Paraoxonase-1 but not Paraoxonase-3 Protein Levels in Human-Derived Liver (HepG2) Cells.Other primary literatureHumanActiveBalkan medical journal2017
Sayılan Özgün G, Özgün E, Tabakçıoğlu K, et al.
Caffeine-induced food-avoidance behavior is mediated by neuroendocrine signals in Caenorhabditis elegans.Other primary literatureAnimalActiveBMB reports2017
Min H, Youn E, Kawasaki I, et al.
The Effects of Caffeine on the Long Bones and Testes in Immature and Young Adult Rats.Other primary literatureUnknownActiveToxicological research2017
Kwak Y, Choi H, Roh J
[Changes of carbohydrate and lipid metabolism in women during pregnancy taking caffeine].ReviewHumanActivePolski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego2017
Cendrowska-Pinkosz M, Dworzański W, Krauze M, et al.
[Caffeine and adaptive changes in the circulatory system during pregnancy].ReviewHumanActivePolski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego2017
Cendrowska-Pinkosz M, Dworzański W, Krauze M, et al.
Adverse Effects of Caffeine on Development of Femur of BALB/c Mice and Protective Role of Vitamin D3.Other primary literatureAnimalActiveJournal of the College of Physicians and Surgeons--Pakistan : JCPSP2017
Khan M, Butt SA
Maternal caffeine intake during pregnancy, early growth, and body fat distribution at school age.Other primary literatureHumanActiveObesity (Silver Spring, Md.)2016
Voerman E, Jaddoe VW, Gishti O, et al.
Application of a Physiologically Based Pharmacokinetic Model to Study Theophylline Metabolism and Its Interactions With Ciprofloxacin and Caffeine.Other primary literatureHumanActiveCPT: pharmacometrics & systems pharmacology2016
Navid A, Ng DM, Wong SE, et al.
Caffeine enhances the antidepressant-like activity of common antidepressant drugs in the forced swim test in mice.Other primary literatureAnimalActiveNaunyn-Schmiedeberg's archives of pharmacology2016
Szopa A, Poleszak E, Wyska E, et al.
Separate and joint effects of alcohol and caffeine on conflict monitoring and adaptation.Randomized controlled trialHumanActivePsychopharmacology2016
Bailey K, Amlung MT, Morris DH, et al.
Mechanisms of the psychostimulant effects of caffeine: implications for substance use disorders.ReviewHuman & animalActivePsychopharmacology2016
Ferré S
Nicotinic acetylcholine receptor availability in cigarette smokers: effect of heavy caffeine or marijuana use.Other primary literatureHumanActivePsychopharmacology2016
Brody AL, Hubert R, Mamoun MS, et al.
Intralipid in acute caffeine intoxication: a case report.Other primary literatureHumanActiveJournal of anesthesia2016
Muraro L, Longo L, Geraldini F, et al.
Synergistic antidepressant-like effect of the joint administration of caffeine and NMDA receptor ligands in the forced swim test in mice.Other primary literatureAnimalActiveJournal of neural transmission (Vienna, Austria : 1996)2016
Serefko A, Szopa A, Wlaź A, et al.
Caffeine toxicity in forensic practice: possible effects and under-appreciated sources.ReviewHumanActiveForensic science, medicine, and pathology2016
Musgrave IF, Farrington RL, Hoban C, et al.
Combined Effects of Simultaneous Exposure to Caffeine and Cocaine in the Mouse Striatum.Other primary literatureAnimalActiveNeurotoxicity research2016
Muñiz JA, Gomez G, González B, et al.
A Retrospective Study of Clinical Effects of Powdered Caffeine Exposures Reported to Three US Poison Control Centers.Other primary literatureHumanActiveJournal of medical toxicology : official journal of the American College of Medical Toxicology2016
Beauchamp GA, Johnson AR, Crouch BI, et al.
Characterisation and growth kinetics studies of caffeine-degrading bacterium Leifsonia sp. strain SIUOther primary literatureUnknownUnknownAnnals of microbiology.2016
Ibrahim S, Shukor MY, Syed MA, et al.
Bioequivalence and Pharmacokinetic Evaluation Study of Acetaminophen vs. Acetaminophen Plus Caffeine Tablets in Healthy Mexican Volunteers.Randomized controlled trialHumanActiveDrugs in R&D2016
Guzmán NA, Molina DR, Núñez BF, et al.
Concentration- and age-dependent effects of chronic caffeine on contextual fear conditioning in C57BL/6J mice.Other primary literatureAnimalActiveBehavioural brain research2016
Poole RL, Braak D, Gould TJ
Inhibiting c-Jun N-terminal kinase partially attenuates caffeine-dependent cell death without alleviating the caffeine-induced reduction in mitochondrial respiration in C2C12 skeletal myotubes.Other primary literatureAnimalActiveBiochemical and biophysical research communications2016
Downs RM, Hughes MA, Kinsey ST, et al.
Involvement of acetylcholinesterase and protein kinase C in the protective effect of caffeine against β-amyloid-induced alterations in red blood cells.Other primary literatureHumanActiveBiochimie2016
Carelli-Alinovi C, Ficarra S, Russo AM, et al.
Hediste diversicolor as bioindicator of pharmaceutical pollution: Results from single and combined exposure to carbamazepine and caffeine.Other primary literatureAnimalActiveComparative biochemistry and physiology. Toxicology & pharmacology : CBP2016
Pires A, Almeida Â, Calisto V, et al.
Long-term exposure to caffeine and carbamazepine: Impacts on the regenerative capacity of the polychaete Diopatra neapolitana.Other primary literatureAnimalActiveChemosphere2016
Pires A, Almeida Â, Correia J, et al.
The Role of Caffeine in Noninvasive Respiratory Support.ReviewHumanActiveClinics in perinatology2016
Dobson NR, Patel RM
Confocal Raman microscopy and multivariate statistical analysis for determination of different penetration abilities of caffeine and propylene glycol applied simultaneously in a mixture on porcine skin ex vivo.Other primary literatureAnimalActiveEuropean journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V2016
Mujica Ascencio S, Choe C, Meinke MC, et al.
Long-term exposure of polychaetes to caffeine: Biochemical alterations induced in Diopatra neapolitana and Arenicola marina.Other primary literatureAnimalActiveEnvironmental pollution (Barking, Essex : 1987)2016
Pires A, Almeida Â, Calisto V, et al.
Neuroprotection by caffeine in the MPTP model of parkinson's disease and its dependence on adenosine A2A receptors.Other primary literatureAnimalActiveNeuroscience2016
Xu K, Di Luca DG, Orrú M, et al.
Caffeine consumption, insomnia, and sleep duration: Results from a nationally representative sample.Other primary literatureHumanActiveNutrition (Burbank, Los Angeles County, Calif.)2016
Chaudhary NS, Grandner MA, Jackson NJ, et al.
Injection of Cocaine-Amphetamine Regulated Transcript (CART) peptide into the nucleus accumbens does not inhibit caffeine-induced locomotor activity: Implications for CART peptide mechanism.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior2016
Job MO
Influence of caffeine on the protective activity of gabapentin and topiramate in a mouse model of generalized tonic-clonic seizures.Other primary literatureAnimalCorrectedPharmacological reports : PR2016
Jargiełło-Baszak M, Chrościńska-Krawczyk M, Andres-Mach M, et al.
Caffeine and caffeinated beverage consumption and fecundability in a preconception cohort.Other primary literatureHumanActiveReproductive toxicology (Elmsford, N.Y.)2016
Wesselink AK, Wise LA, Rothman KJ, et al.
Use of an integrated biomarker-based strategy to evaluate physiological stress responses induced by environmental concentrations of caffeine in the Mediterranean mussel Mytilus galloprovincialis.Other primary literatureAnimalActiveThe Science of the total environment2016
Capolupo M, Valbonesi P, Kiwan A, et al.
Effects of caffeine on cell viability and activity of histone deacetylase 1 and histone acetyltransferase in glioma cells.Other primary literatureUnknownActiveTzu chi medical journal2016
Chen JC, Hwang JH
The acute lethal dose 50 (LD50) of caffeine in albino rats.Other primary literatureAnimalActiveRegulatory toxicology and pharmacology : RTP2016
Adamson RH
Maternal caffeine intake during pregnancy and risk of pregnancy loss: a categorical and dose-response meta-analysis of prospective studies.Meta-analysisHumanActivePublic health nutrition2016
Chen LW, Wu Y, Neelakantan N, et al.
Engineering an ABC Transporter for Enhancing Resistance to Caffeine in Saccharomyces cerevisiae.Other primary literatureUnknownActiveJournal of agricultural and food chemistry2016
Wang M, Deng WW, Zhang ZZ, et al.
A brief manualized treatment for problematic caffeine use: A randomized control trial.Randomized controlled trialHumanActiveJournal of consulting and clinical psychology2016
Evatt DP, Juliano LM, Griffiths RR
Pharmacologic synergism of ocular ketorolac and systemic caffeine citrate in rat oxygen-induced retinopathy.Other primary literatureAnimalActivePediatric research2016
Aranda JV, Cai CL, Ahmad T, et al.
Caffeine intake antagonizes salt sensitive hypertension through improvement of renal sodium handling.Other primary literatureAnimalActiveScientific reports2016
Yu H, Yang T, Gao P, et al.
Caffeine administration prevents retinal neuroinflammation and loss of retinal ganglion cells in an animal model of glaucoma.Other primary literatureHuman & animalActiveScientific reports2016
Madeira MH, Ortin-Martinez A, Nadal-Nícolas F, et al.
In Utero Caffeine Exposure Induces Transgenerational Effects on the Adult Heart.Other primary literatureUnknownActiveScientific reports2016
Fang X, Poulsen RR, Rivkees SA, et al.
Prenatal caffeine exposure-induced adrenal developmental abnormality in male offspring rats and its possible intrauterine programming mechanisms.Other primary literatureUnknownActiveToxicology research2016
He Z, Zhu C, Huang H, et al.
Caffeine fostering of mycoparasitic fungi against phytopathogens.Other primary literatureUnknownActivePlant signaling & behavior2016
Sugiyama A, Sano CM, Yazaki K, et al.
Effects of coffee and caffeine anhydrous on strength and sprint performance.Randomized controlled trialHumanActiveEuropean journal of sport science2016
Trexler ET, Smith-Ryan AE, Roelofs EJ, et al.
Concurrent Validity of Caffeine Problems and Diagnostic Criteria for Substance Use Disorders.Other primary literatureUnknownActiveJournal of caffeine research2016
Harstad E, Sideridis G, Sherritt L, et al.
Early High-Dose Caffeine Increases Seizure Burden in Extremely Preterm Neonates: A Preliminary Study.Other primary literatureUnknownActiveJournal of caffeine research2016
Vesoulis ZA, McPherson C, Neil JJ, et al.
Relationships Between Caffeine Intake and Risk for Probable Dementia or Global Cognitive Impairment: The Women's Health Initiative Memory Study.Randomized controlled trialHumanActiveThe journals of gerontology. Series A, Biological sciences and medical sciences2016
Driscoll I, Shumaker SA, Snively BM, et al.
Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior.Other primary literatureHumanActiveHuman molecular genetics2016
Cornelis MC, Kacprowski T, Menni C, et al.
Effects of Caffeine and Lycopene in Experimentally Induced Diabetes Mellitus.Other primary literatureAnimalActivePancreas2016
Ozmen O, Topsakal S, Haligur M, et al.
Concomitant Caffeine Increases Binge Consumption of Ethanol in Adolescent and Adult Mice, But Produces Additive Motor Stimulation Only in Adolescent Animals.Other primary literatureAnimalActiveAlcoholism, clinical and experimental research2016
Fritz BM, Quoilin C, Kasten CR, et al.
Desire to Drink Alcohol is Enhanced with High Caffeine Energy Drink Mixers.Other primary literatureHumanActiveAlcoholism, clinical and experimental research2016
Marczinski CA, Fillmore MT, Stamates AL, et al.
Salivary caffeine concentrations are comparable to plasma concentrations in preterm infants receiving extended caffeine therapy.Other primary literatureHumanActiveBritish journal of clinical pharmacology2016
Dobson NR, Liu X, Rhein LM, et al.
The Safety, Pharmacokinetics, and Nervous System Effects of Two Natural Sources of Caffeine in Healthy Adult Males.Other primary literatureUnknownActiveClinical and translational science2016
Krieger DR, Kalman DS, Feldman S, et al.
Endothelial Nitric Oxide Mediates Caffeine Antagonism of Alcohol-Induced Cerebral Artery Constriction.Other primary literatureAnimalActiveThe Journal of pharmacology and experimental therapeutics2016
Chang J, Fedinec AL, Kuntamallappanavar G, et al.
In Vivo and In Vitro Genotoxic and Epigenetic Effects of Two Types of Cola Beverages and Caffeine: A Multiassay Approach.Other primary literatureHuman & animalActiveBioMed research international2016
Mateo-Fernández M, Merinas-Amo T, Moreno-Millán M, et al.
Timing of Caffeine Therapy and Neonatal Outcomes in Preterm Infants: A Retrospective Study.Other primary literatureUnknownActiveInternational journal of pediatrics2016
Hand I, Zaghloul N, Barash L, et al.
The Real-World Routine Use of Caffeine Citrate in Preterm Infants: A European Postauthorization Safety Study.Observational studyHumanActiveNeonatology2016
Lista G, Fabbri L, Polackova R, et al.
Electrocardiogram Abnormalities of Caffeine Overdose.Other primary literatureHumanActiveCirculation. Arrhythmia and electrophysiology2016
Fabrizio C, Desiderio M, Coyne RF
Caffeine alters the behavioural and body temperature responses to mephedrone without causing long-term neurotoxicity in rats.Other primary literatureAnimalActiveJournal of psychopharmacology (Oxford, England)2016
Shortall SE, Green AR, Fone KC, et al.
Pretreatment With Caffeine Citrate to Increase Seizure Duration During Electroconvulsive Therapy: A Case Series.Other primary literatureHumanActiveJournal of pharmacy practice2016
Pinkhasov A, Biglow M, Chandra S, et al.
Comparison of pharmaceutical, illicit drug, alcohol, nicotine and caffeine levels in wastewater with sale, seizure and consumption data for 8 European cities.Other primary literatureHumanActiveBMC public health2016
Baz-Lomba JA, Salvatore S, Gracia-Lor E, et al.
Oral intake of a combination of glucosyl hesperidin and caffeine elicits an anti-obesity effect in healthy, moderately obese subjects: a randomized double-blind placebo-controlled trial.Randomized controlled trialHumanCorrectedNutrition journal2016
Ohara T, Muroyama K, Yamamoto Y, et al.
Acute caffeine ingestion reduces insulin sensitivity in healthy subjects: a systematic review and meta-analysis.Meta-analysisHumanActiveNutrition journal2016
Shi X, Xue W, Liang S, et al.
The influence of caffeine ingestion on strength and power performance in female team-sport players.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2016
Ali A, O'Donnell J, Foskett A, et al.
Does caffeine reduce postoperative bowel paralysis after elective laparoscopic colectomy? (CaCo trial): study protocol for a randomized controlled trial.Randomized controlled trialHumanActiveTrials2016
Kruse C, Müller SA, Warschkow R, et al.
Is caffeine intake a risk factor leading to infertility? A protocol of an epidemiological systematic review of controlled clinical studies.Other primary literatureHumanActiveSystematic reviews2016
Cao H, Ren J, Feng X, et al.
Results from a pharmacy-based patient survey on the use of a fixed combination analgesic containing acetylsalicylic acid, paracetamol and caffeine by self-diagnosing and self-treating patients.Other primary literatureUnknownActiveSpringerPlus2016
Gaul C, Gräter H, Weiser T
Incorporating pharmacodynamic considerations into caffeine therapeutic drug monitoring in preterm neonates.Observational studyHumanActiveBMC pharmacology & toxicology2016
Yu T, Balch AH, Ward RM, et al.
Survival of ingestion of a potentially lethal dose of caffeine.Other primary literatureHumanActiveBritish journal of hospital medicine (London, England : 2005)2016
Gibson JL, Nesbitt I, Dinsdale A, et al.
Up Regulation of cystathione γ lyase and Hydrogen Sulphide in the Myocardium Inhibits the Progression of Isoproterenol-Caffeine Induced Left Ventricular Hypertrophy in Wistar Kyoto Rats.Other primary literatureAnimalActivePloS one2016
Ahmad A, Sattar MA, Rathore HA, et al.
Unique Behavioral and Neurochemical Effects Induced by Repeated Adolescent Consumption of Caffeine-Mixed Alcohol in C57BL/6 Mice.Other primary literatureHuman & animalActivePloS one2016
Robins MT, Lu J, van Rijn RM
The Effects of Caffeine Supplementation on Physiological Responses to Submaximal Exercise in Endurance-Trained Men.Randomized controlled trialHumanActivePloS one2016
Glaister M, Williams BH, Muniz-Pumares D, et al.
Caffeine Induces the Stress Response and Up-Regulates Heat Shock Proteins in Caenorhabditis elegans.Other primary literatureAnimalActiveMolecules and cells2016
Al-Amin M, Kawasaki I, Gong J, et al.
Effects of Coffee and Caffeine Anhydrous Intake During Creatine Loading.Randomized controlled trialHumanActiveJournal of strength and conditioning research2016
Trexler ET, Smith-Ryan AE, Roelofs EJ, et al.
Potential Role of Caffeine in the Treatment of Parkinson's Disease.Other primary literatureUnknownActiveThe open neurology journal2016
Roshan MH, Tambo A, Pace NP
Non-toxic Efficacy of the Combination of Caffeine and Valproic Acid on Human Osteosarcoma Cells In Vitro and in Orthotopic Nude-mouse Models.Other primary literatureHuman & animalActiveAnticancer research2016
Igarashi K, Yamamoto N, Hayashi K, et al.
Prenatal Caffeine Exposure Impairs Pregnancy in Rats.Other primary literatureUnknownActiveInternational journal of fertility & sterility2016
Yadegari M, Khazaei M, Anvari M, et al.
Neuroprotective, antiapoptotic and antioxidant effects of l-carnitine against caffeine-induced neurotoxicity in SH-SY5Y neuroblastoma cell line.Other primary literatureHumanActiveDrug and chemical toxicology2016
Bavari M, Tabandeh MR, Najafzadeh Varzi H, et al.
Quantitative analysis of powdered caffeine products purchased from the Internet using liquid chromatography-quadrupole time-of-flight mass spectrometry.Other primary literatureUnknownActiveClinical toxicology (Philadelphia, Pa.)2016
Beauchamp GA, Lin T, Zeng WZ, et al.
Atrial arrhythmia after newborn eye exam, to caffeine or not to caffeine?Other primary literatureHumanActiveJournal of neonatal-perinatal medicine2016
Ahmad A, Mondal T, Klein B
Caffeine Taste Signaling in Drosophila Larvae.Other primary literatureUnknownActiveFrontiers in cellular neuroscience2016
Apostolopoulou AA, Köhn S, Stehle B, et al.
Caffeine Consumption and General Health in Secondary School Children: A Cross-sectional and Longitudinal Analysis.Other primary literatureUnknownActiveFrontiers in nutrition2016
Richards G, Smith AP
A Cytochrome P450 3A4 Biosensor Based on Generation 4.0 PAMAM Dendrimers for the Detection of Caffeine.Other primary literatureUnknownActiveBiosensors2016
Müller M, Agarwal N, Kim J
Caffeine Use among Active Duty Navy and Marine Corps Personnel.Other primary literatureHumanActiveNutrients2016
Knapik JJ, Trone DW, McGraw S, et al.
[Clinical effectiveness of different doses of caffeine for primary apnea in preterm infants].Randomized controlled trialHumanActiveZhonghua er ke za zhi = Chinese journal of pediatrics2016
Zhao Y, Tian X, Liu G
Beneficial Role of Coffee and Caffeine in Neurodegenerative Diseases: A Minireview.ReviewUnknownActiveAIMS public health2016
Sc Y, Muralidhara
Serum caffeine and paraxanthine concentrations and menstrual cycle function: correlations with beverage intakes and associations with race, reproductive hormones, and anovulation in the BioCycle Study.Other primary literatureHumanActiveThe American journal of clinical nutrition2016
Schliep KC, Schisterman EF, Wactawski-Wende J, et al.
A prospective study of caffeine and coffee intake and premenstrual syndrome.Other primary literatureHumanActiveThe American journal of clinical nutrition2016
Purdue-Smithe AC, Manson JE, Hankinson SE, et al.
Pharmacokinetic Interaction of Chrysin with Caffeine in Rats.Other primary literatureUnknownActiveBiomolecules & therapeutics2016
Noh K, Oh do G, Nepal MR, et al.
The Relationship of Caffeine Intake with Depression, Anxiety, Stress, and Sleep in Korean Adolescents.Other primary literatureUnknownActiveKorean journal of family medicine2016
Jin MJ, Yoon CH, Ko HJ, et al.
The effects of caffeine administered at different temperatures on foetal development.Other primary literatureAnimalActiveAnnals of agricultural and environmental medicine : AAEM2016
Tomaszewski M, Burdan F, Olchowik G, et al.
The influence of caffeine administered at 10°C on bone tissue development.Other primary literatureAnimalActiveAnnals of agricultural and environmental medicine : AAEM2016
Tomaszewski M, Olchowik G, Tomaszewska M, et al.
The Role of Caffeine in Pain Management: A Brief Literature Review.ReviewUnknownActiveAnesthesiology and pain medicine2016
Baratloo A, Rouhipour A, Forouzanfar MM, et al.
Simultaneous coffee caffeine intake and sleep deprivation alter glucose homeostasis in Iranian men: a randomized crossover trial.Randomized controlled trialHumanActiveAsia Pacific journal of clinical nutrition2016
Rasaei B, Talib RA, Noor MI, et al.
A Rare Case of Caffeine Storm due to Excessive Coca-Cola Consumption.Other primary literatureHumanActiveThe Israel Medical Association journal : IMAJ2016
Love IY, Perl S, Rapoport MJ
[Qualitative and quantitative determination of caffeine in saliva by high performance liquid chromatography].Other primary literatureHumanActivePrzeglad lekarski2016
Napierała M, Florek E
Caffeine Consumption Behaviors of the Working-Age Population in Rural Communities in Northeastern Thailand.Other primary literatureHumanActiveJournal of the Medical Association of Thailand = Chotmaihet thangphaet2016
Polsripradist P, Tantayaporn K, Homchampa P
Current state of caffeine intoxication.Other primary literatureHumanActiveChudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology2016
Hirakawa A
Still without Sales Restriction? Fatal Caffeine Toxicity A case report.Other primary literatureHumanActiveNihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence2016
Nakamura M, Idota N, Shint Ani-Ishida K, et al.
An autopsy case of caffeine intoxication related by energy drink.ReviewHumanActiveNihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence2016
Takayama M, Waters B, Hara K, et al.
Association of early caffeine administration and neonatal outcomes in very preterm neonates.Observational studyHumanActiveJAMA pediatrics2015
Lodha A, Seshia M, McMillan DD, et al.
Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcomes.Systematic reviewHumanActiveThe Cochrane database of systematic reviews2015
Jahanfar S, Jaafar SH
Single dose oral ibuprofen plus caffeine for acute postoperative pain in adults.Meta-analysisHumanActiveThe Cochrane database of systematic reviews2015
Derry S, Wiffen PJ, Moore RA
The effect of caffeine and albuterol on body composition and metabolic rate.Randomized controlled trialHuman & animalActiveObesity (Silver Spring, Md.)2015
Liu AG, Arceneaux KP 3rd, Chu JT, et al.
Caffeine improves reaction time, vigilance and logical reasoning during extended periods with restricted opportunities for sleep.Randomized controlled trialHumanActivePsychopharmacology2015
Kamimori GH, McLellan TM, Tate CM, et al.
Prediction of plasma caffeine concentrations in young adolescents following ingestion of caffeinated energy drinks: a Monte Carlo simulation.Other primary literatureHumanActiveEuropean journal of pediatrics2015
Lee JW, Kim Y, Perera V, et al.
Investigations of the presence of caffeine in the Rudawa River, Kraków, Poland.Other primary literatureUnknownActiveEnvironmental monitoring and assessment2015
Jagoda A, Żukowski W, Dąbrowska B
The role of adenosine A1 and A2A receptors in the caffeine effect on MDMA-induced DA and 5-HT release in the mouse striatum.Other primary literatureAnimalActiveNeurotoxicity research2015
Górska AM, Gołembiowska K
Autophagy inhibition by caffeine increases toxicity of methamphetamine in SH-SY5Y neuroblastoma cell line.Other primary literatureHumanActiveNeurotoxicity research2015
Pitaksalee R, Sanvarinda Y, Sinchai T, et al.
Succesfull treatment of supralethal caffeine overdose with a combination of lipid infusion and dialysis.Other primary literatureHumanActiveThe American journal of emergency medicine2015
Schmidt M, Farna H, Kurcova I, et al.
Yes, caffeine, ibuprofen, carbamazepine, novobiocin and tamoxifen have an effect on Corbicula fluminea (Müller, 1774).Other primary literatureAnimalActiveEcotoxicology and environmental safety2015
Aguirre-Martínez GV, DelValls AT, Laura Martín-Díaz M
Pressurized liquid extraction of caffeine and catechins from green tea leaves using ethyl lactate, water and ethyl lactate+water mixturesOther primary literatureUnknownUnknownFood and Bioproducts Processing.2015
Bermejo DV, Mendiola JA, Ibáñez E, et al.
In vitro-to-in vivo correlation of the skin penetration, liver clearance and hepatotoxicity of caffeine.Other primary literatureHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2015
Gajewska M, Paini A, Sala Benito JV, et al.
A beating heart cell model to predict cardiotoxicity: effects of the dietary supplement ingredients higenamine, phenylethylamine, ephedrine and caffeine.Other primary literatureHuman & animalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2015
Calvert R, Vohra S, Ferguson M, et al.
Removal of caffeine from aqueous solution by indirect electrochemical oxidation using a graphite-PVC composite electrode: A role of hypochlorite ion as an oxidising agent.Other primary literatureUnknownActiveJournal of hazardous materials2015
Al-Qaim FF, Mussa ZH, Othman MR, et al.
The role of salivary caffeine clearance in the diagnosis of chronic liver disease.Other primary literatureUnknownActiveJournal of oral biology and craniofacial research2015
Tripathi A, Tiwari B, Patil R, et al.
Caffeine and diuresis during rest and exercise: A meta-analysis.Meta-analysisHumanActiveJournal of science and medicine in sport2015
Zhang Y, Coca A, Casa DJ, et al.
Non specific drug distribution in an autopsy case report of fatal caffeine intoxication.Other primary literatureHumanActiveLegal medicine (Tokyo, Japan)2015
Ishikawa T, Yuasa I, Endoh M
Low concentrations of caffeine induce asymmetric cell division as observed in vitro by means of the CBMN-assay and iFISH.Other primary literatureUnknownActiveMutation research. Genetic toxicology and environmental mutagenesis2015
Hatzi VI, Karakosta M, Barszczewska K, et al.
Caffeine does not entrain the circadian clock but improves daytime alertness in blind patients with non-24-hour rhythms.Other primary literatureHumanActiveSleep medicine2015
St Hilaire MA, Lockley SW
Maternal caffeine intake during pregnancy and risk of obesity in offspring: a prospective cohort study.Other primary literatureHumanActiveInternational journal of obesity (2005)2015
Li DK, Ferber JR, Odouli R
Gut microbiota mediate caffeine detoxification in the primary insect pest of coffee.Other primary literatureAnimalCorrectedNature communications2015
Ceja-Navarro JA, Vega FE, Karaoz U, et al.
Effects of adolescent caffeine consumption on cocaine sensitivity.Other primary literatureHuman & animalActiveNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2015
O'Neill CE, Levis SC, Schreiner DC, et al.
A pilot randomized trial of high-dose caffeine therapy in preterm infants.Randomized controlled trialHumanActivePediatric research2015
McPherson C, Neil JJ, Tjoeng TH, et al.
Chronic fetal exposure to caffeine altered resistance vessel functions via RyRs-BKCa down-regulation in rat offspring.Other primary literatureAnimalActiveScientific reports2015
Li N, Li Y, Gao Q, et al.
Prenatal caffeine exposure induces a poor quality of articular cartilage in male adult offspring rats via cholesterol accumulation in cartilage.Other primary literatureAnimalActiveScientific reports2015
Luo H, Li J, Cao H, et al.
Subjective Responses to Caffeine Are Influenced by Caffeine Dose, Sex, and Pubertal Stage.Other primary literatureUnknownActiveJournal of caffeine research2015
Temple JL, Ziegler AM, Martin C, et al.
Letter to the editor--The problem of caffeine consumption in the bodybuilding scene.Other primary literatureHumanActiveJournal of forensic sciences2015
Dziadosz M, Klintschar M, Teske J
Sensitization and Tolerance Following Repeated Exposure to Caffeine and Alcohol in Mice.Other primary literatureAnimalActiveAlcoholism, clinical and experimental research2015
May CE, Haun HL, Griffin WC 3rd
Polysomnographic sleep disturbances in nicotine, caffeine, alcohol, cocaine, opioid, and cannabis use: A focused review.ReviewHumanActiveThe American journal on addictions2015
Garcia AN, Salloum IM
What can isolated skeletal muscle experiments tell us about the effects of caffeine on exercise performance?ReviewHuman & animalActiveBritish journal of pharmacology2015
Tallis J, Duncan MJ, James RS
Caffeine Mitigates Lung Inflammation Induced by Ischemia-Reperfusion of Lower Limbs in Rats.Other primary literatureAnimalActiveMediators of inflammation2015
Chou WC, Kao MC, Yue CT, et al.
High Doses of Caffeine during the Peripubertal Period in the Rat Impair the Growth and Function of the Testis.Other primary literatureUnknownActiveInternational journal of endocrinology2015
Park M, Choi Y, Choi H, et al.
Downregulation of mPGES-1 Expression via EGR1 Plays an Important Role in Inhibition of Caffeine on PGE2 Synthesis of HBx(+) Hepatocytes.Other primary literatureHumanActiveMediators of inflammation2015
Ma Y, Wang X, Tang N
Tramadol and Tramadol+Caffeine Synergism in the Rat Formalin Test Are Mediated by Central Opioid and Serotonergic Mechanisms.Other primary literatureAnimalActiveBioMed research international2015
Carrillo-Munguía N, González-Trujano ME, Huerta M, et al.
Public Concern about the Sale of High-Caffeine Drinks to Children 12 Years or Younger: An Australian Regulatory Perspective.Other primary literatureHumanActiveBioMed research international2015
Pollard CM, McStay CL, Meng X
Effect of various concentrations of caffeine, pentoxifylline, and kallikrein on hyperactivation of frozen bovine semen.Other primary literatureHuman & animalActiveBioMed research international2015
Barakat IA, Danfour MA, Galewan FA, et al.
Caffeine consumption and self-assessed stress, anxiety, and depression in secondary school children.Other primary literatureHumanActiveJournal of psychopharmacology (Oxford, England)2015
Richards G, Smith A
Associations between night work and BMI, alcohol, smoking, caffeine and exercise--a cross-sectional study.Other primary literatureHumanActiveBMC public health2015
Buchvold HV, Pallesen S, Øyane NM, et al.
Osteogenic potential of osteoblasts from neonatal rats born to mothers treated with caffeine throughout pregnancy.Other primary literatureAnimalActiveBMC musculoskeletal disorders2015
Reis AM, Ribeiro LG, Ocarino Nde M, et al.
Caffeine reduces hepatic lipid accumulation through regulation of lipogenesis and ER stress in zebrafish larvae.Other primary literatureHuman & animalActiveJournal of biomedical science2015
Zheng X, Dai W, Chen X, et al.
The effects of supplementation with P-Synephrine alone and in combination with caffeine on resistance exercise performance.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2015
Ratamess NA, Bush JA, Kang J, et al.
Assessing developmental toxicity of caffeine and sweeteners in medaka (Oryzias latipes).Other primary literatureUnknownActiveSpringerPlus2015
Lee W, Wang YC
A novel topical targeting system of caffeine microemulsion for inhibiting UVB-induced skin tumor: characterization, optimization, and evaluation.Other primary literatureAnimalActiveAAPS PharmSciTech2015
Ma H, Yu M, Lei M, et al.
The effects of levetiracetam, sumatriptan, and caffeine in a rat model of trigeminal pain: interactions in 2-component combinations.Other primary literatureAnimalActiveAnesthesia and analgesia2015
Tomić MA, Pecikoza UB, Micov AM, et al.
Autopsy report for a caffeine intoxication case and review of the current literature.Other primary literatureUnknownCorrectedJournal of toxicologic pathology2015
Yamamoto T, Yoshizawa K, Kubo S, et al.
Cytochrome P450-dependent metabolism of caffeine in Drosophila melanogaster.Other primary literatureAnimalActivePloS one2015
Coelho A, Fraichard S, Le Goff G, et al.
Caffeine Modulates Vesicle Release and Recovery at Cerebellar Parallel Fibre Terminals, Independently of Calcium and Cyclic AMP Signalling.Other primary literatureAnimalActivePloS one2015
Dobson KL, Jackson C, Balakrishnan S, et al.
No Enhancement of 24-Hour Visuomotor Skill Retention by Post-Practice Caffeine Administration.Randomized controlled trialHumanActivePloS one2015
Hussain SJ, Cole KJ
Caffeine Consumption and Heart Rate and Blood Pressure Response to Regadenoson.Other primary literatureHumanActivePloS one2015
Bitar A, Mastouri R, Kreutz RP
Maternal Caffeine Consumption during Pregnancy and Risk of Low Birth Weight: A Dose-Response Meta-Analysis of Observational Studies.Meta-analysisHumanActivePloS one2015
Rhee J, Kim R, Kim Y, et al.
Psychostimulant-Induced Testicular Toxicity in Mice: Evidence of Cocaine and Caffeine Effects on the Local Dopaminergic System.Other primary literatureAnimalActivePloS one2015
González CR, González B, Matzkin ME, et al.
Caffeine induces high expression of cyp-35A family genes and inhibits the early larval development in Caenorhabditis elegans.Other primary literatureAnimalActiveMolecules and cells2015
Min H, Kawasaki I, Gong J, et al.
Mode of daily caffeine consumption among adolescents and the practice of mixing alcohol with energy drinks: relationships to drunkenness.Other primary literatureHumanActiveJournal of studies on alcohol and drugs2015
Kristjansson AL, Mann MJ, Sigfusdottir ID, et al.
Caffeine affects the biological responses of human hematopoietic cells of myeloid lineage via downregulation of the mTOR pathway and xanthine oxidase activity.Other primary literatureHumanActiveOncotarget2015
Gibbs BF, Gonçalves Silva I, Prokhorov A, et al.
Coffee and caffeine potentiate the antiamyloidogenic activity of melatonin via inhibition of Aβ oligomerization and modulation of the Tau-mediated pathway in N2a/APP cells.Other primary literatureAnimalRetractedDrug design, development and therapy2015
Zhang LF, Zhou ZW, Wang ZH, et al.
Caffeine: cognitive and physical performance enhancer or psychoactive drug?ReviewHumanCorrectedCurrent neuropharmacology2015
Cappelletti S, Piacentino D, Sani G, et al.
[Severe Caffeine Intentional Intoxication and Delayed Elimination: a Case Report].Other primary literatureHumanActiveTherapie2015
Barreau M, Lambert B, Tobarias J, et al.
[CAFFEINE AND QUININE IN SOFT DRINKS; CONTRIBUTION TO THE DIETARY INTAKE].Other primary literatureUnknownActiveNutricion hospitalaria2015
González Reyes AB, Hardisson de la Torre A, Gutiérrez Fernández AJ, et al.
PERINATAL OUTCOMES OF PREMATURITY AND BIRTH WEIGHT ACCORDING TO MATERNAL CAFFEINE CONSUMPTION.Other primary literatureHumanActiveNutricion hospitalaria2015
Del Castillo N, Jiménez-Moleón JJ, Olmedo-Requena R, et al.
Lifespan Extension Induced by Caffeine in Caenorhabditis elegans is Partially Dependent on Adenosine Signaling.Other primary literatureUnknownActiveFrontiers in aging neuroscience2015
Bridi JC, Barros AG, Sampaio LR, et al.
Development of tumor-specific caffeine-potentiated chemotherapy using a novel drug delivery system with Span 80 nano-vesicles.Other primary literatureHuman & animalActiveOncology reports2015
Nakata H, Miyazaki T, Iwasaki T, et al.
Caffeine intake from food and beverage sources and trends among children and adolescents in the United States: review of national quantitative studies from 1999 to 2011.ReviewHumanActiveAdvances in nutrition (Bethesda, Md.)2015
Ahluwalia N, Herrick K
Urine excretion of caffeine and select caffeine metabolites is common in the U.S. population and associated with caffeine intake.Other primary literatureHumanActiveThe Journal of nutrition2015
Rybak ME, Sternberg MR, Pao CI, et al.
Effects of baicalin on oral pharmacokinetics of caffeine in rats.Other primary literatureUnknownActiveBiomolecules & therapeutics2015
Noh K, Nepal MR, Jeong KS, et al.
Treatment of GABA from Fermented Rice Germ Ameliorates Caffeine-Induced Sleep Disturbance in Mice.Other primary literatureUnknownActiveBiomolecules & therapeutics2015
Mabunga DF, Gonzales EL, Kim HJ, et al.
Quantification of total polyphenols, catechin, caffeine, L-theanine, determination of antioxidant activity and effect on antileishmanial drugs of ethiopian tea leaves extracts.Other primary literatureUnknownActivePharmacognosy research2015
Tadesse A, Hymete A, Bekhit AA, et al.
The perspective of caffeine and caffeine derived compounds in therapy.ReviewHumanActiveBratislavske lekarske listy2015
Pohanka M
Efficacy of Slimming Cream Containing 3.5% Water-Soluble Caffeine and Xanthenes for the Treatment of Cellulite: Clinical Study and Literature Review.Other primary literatureUnknownActiveAnnals of dermatology2015
Byun SY, Kwon SH, Heo SH, et al.
Caffeine therapy in preterm infants.ReviewUnknownActiveWorld journal of clinical pediatrics2015
Abdel-Hady H, Nasef N, Shabaan AE, et al.
Caffeine Awareness in Children: Insights from a Pilot Study.Other primary literatureHumanActiveJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2015
Thakre TP, Deoras K, Griffin C, et al.
The Effects of Caffeine Supplements on Exercise-Induced Oxidative Damages.Other primary literatureUnknownActiveAsian journal of sports medicine2015
Zeraatpishe A, Malekirad AA, Nik-Kherad J, et al.
Caffeine Toxicity Due to Supplement Use in Caffeine--Naïve Individual: A Cautionary Tale.Other primary literatureHumanActiveMilitary medicine2015
Lystrup RM, Leggit JC
Start me up! Recurrent ventricular tachydysrhythmias following intentional concentrated caffeine ingestion.Other primary literatureHumanActiveClinical toxicology (Philadelphia, Pa.)2015
Laskowski LK, Henesch JA, Nelson LS, et al.
The effect of caffeine on cerebral asymmetry in rats.Other primary literatureAnimalActiveJournal of medicine and life2015
Voiculescu M, Segarceanu A, Negutu M, et al.
Caffeine as an analgesic adjuvant for acute pain in adults.Meta-analysisHumanActiveThe Cochrane database of systematic reviews2014
Derry CJ, Derry S, Moore RA
Plasma lactate concentration as an indicator of plasma caffeine concentration in acute caffeine poisoning.Other primary literatureUnknownActiveAcute medicine & surgery2014
Morita S, Yamagiwa T, Aoki H, et al.
Individual and mixture effects of caffeine and sulfamethoxazole on the daggerblade grass shrimp Palaemonetes pugio following maternal exposure.Other primary literatureAnimalActiveEnvironmental toxicology and chemistry2014
Garcia RN, Chung KW, DeLorenzo ME, et al.
Effects of two doses of glucose and a caffeine-glucose combination on cognitive performance and mood during multi-tasking.Randomized controlled trialHumanActiveHuman psychopharmacology2014
Scholey A, Savage K, O'Neill BV, et al.
Caffeine alters resting-state functional connectivity measured by blood oxygenation level-dependent MRI.Other primary literatureHumanActiveNMR in biomedicine2014
Wu WC, Lien SH, Chang JH, et al.
Effects of upper respiratory tract illnesses, ibuprofen and caffeine on reaction time and alertness.Randomized controlled trialHumanActivePsychopharmacology2014
Smith AP, Nutt DJ
Oral caffeine administration ameliorates acute colitis by suppressing chitinase 3-like 1 expression in intestinal epithelial cells.Other primary literatureAnimalActiveJournal of gastroenterology2014
Lee IA, Low D, Kamba A, et al.
Effect of taurine and potential interactions with caffeine on cardiovascular function.ReviewHumanActiveAmino acids2014
Schaffer SW, Shimada K, Jong CJ, et al.
Effect of caffeine on SPECT myocardial perfusion imaging during regadenoson pharmacologic stress: a prospective, randomized, multicenter study.Randomized controlled trialHumanActiveThe international journal of cardiovascular imaging2014
Tejani FH, Thompson RC, Kristy R, et al.
Caffeine intake during pregnancy and adverse birth outcomes: a systematic review and dose-response meta-analysis.Meta-analysisHumanActiveEuropean journal of epidemiology2014
Greenwood DC, Thatcher NJ, Ye J, et al.
Maternal caffeine consumption and small for gestational age births: results from a population-based case-control study.Other primary literatureHumanActiveMaternal and child health journal2014
Hoyt AT, Browne M, Richardson S, et al.
Exploring maternal patterns of dietary caffeine consumption before conception and during pregnancy.Other primary literatureHumanActiveMaternal and child health journal2014
Chen L, Bell EM, Browne ML, et al.
A case of suicide by ingestion of caffeine.Other primary literatureHumanActiveForensic science, medicine, and pathology2014
Bonsignore A, Sblano S, Pozzi F, et al.
Caffeine in tea Camellia sinensis--content, absorption, benefits and risks of consumption.ReviewHumanActiveThe journal of nutrition, health & aging2014
Gramza-Michałowska A
Current evidence for the use of coffee and caffeine to prevent age-related cognitive decline and Alzheimer's disease.ReviewHuman & animalActiveThe journal of nutrition, health & aging2014
Carman AJ, Dacks PA, Lane RF, et al.
The effect of caffeine ingestion on functional performance in older adults.Randomized controlled trialHumanActiveThe journal of nutrition, health & aging2014
Duncan MJ, Clarke ND, Tallis J, et al.
Caffeine Use Disorder: A Review of the Evidence and Future Implications.Other primary literatureUnknownActiveCurrent addiction reports2014
Addicott MA
Caffeine overdose resulting in severe rhabdomyolysis and acute renal failure.Other primary literatureHumanActiveThe American journal of emergency medicine2014
Campana C, Griffin PL, Simon EL
Differential concentration-specific effects of caffeine on cell viability, oxidative stress, and cell cycle in pulmonary oxygen toxicity in vitro.Other primary literatureAnimalActiveBiochemical and biophysical research communications2014
Tiwari KK, Chu C, Couroucli X, et al.
Effect of caffeine on cervical vestibular-evoked myogenic potential in healthy individuals.Other primary literatureHumanActiveBrazilian journal of otorhinolaryngology2014
Sousa AM, Suzuki FA
Reversible neuronal and muscular toxicity of caffeine in developing vertebrates.Other primary literatureAnimalActiveComparative biochemistry and physiology. Toxicology & pharmacology : CBP2014
Rodriguez RS, Haugen R, Rueber A, et al.
Pharmacokinetics for topically applied caffeine in the rat.Other primary literatureAnimalActiveExperimental eye research2014
Kronschläger M, Forsman E, Yu Z, et al.
Chars from gasification of coal and pine activated with K2CO3: acetaminophen and caffeine adsorption from aqueous solutions.Other primary literatureUnknownActiveJournal of colloid and interface science2014
Galhetas M, Mestre AS, Pinto ML, et al.
Ingesting a preworkout supplement containing caffeine, creatine, β-alanine, amino acids, and B vitamins for 28 days is both safe and efficacious in recreationally active men.Randomized controlled trialHumanActiveNutrition research (New York, N.Y.)2014
Kendall KL, Kendall KL, Moon JR, et al.
Augmentation of antidepressant effects of duloxetine and bupropion by caffeine in mice.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior2014
Kale PP, Addepalli V
Ecotoxicological evaluation of caffeine and its derivatives from a simulated chlorination step.Other primary literatureAnimalActiveThe Science of the total environment2014
Zarrelli A, Dellagreca M, Iesce MR, et al.
Impact of caffeine and coffee on our health.ReviewHumanActiveTrends in endocrinology and metabolism: TEM2014
Gonzalez de Mejia E, Ramirez-Mares MV
An in vitro approach to assessing a potential drug interaction between MDMA (ecstasy) and caffeine.Other primary literatureHuman & animalActiveToxicology in vitro : an international journal published in association with BIBRA2014
Downey C, Daly F, O'Boyle KM
Caffeine-based gold(I) N-heterocyclic carbenes as possible anticancer agents: synthesis and biological properties.Other primary literatureHuman & animalActiveInorganic chemistry2014
Bertrand B, Stefan L, Pirrotta M, et al.
Validation of caffeine dehydrogenase from Pseudomonas sp. strain CBB1 as a suitable enzyme for a rapid caffeine detection and potential diagnostic test.Other primary literatureHumanActiveJournal of agricultural and food chemistry2014
Mohanty SK, Yu CL, Gopishetty S, et al.
The effects of caffeine on heart rate variability in newborns with apnea of prematurity.Other primary literatureHumanActiveJournal of perinatology : official journal of the California Perinatal Association2014
Ulanovsky I, Haleluya NS, Blazer S, et al.
Post-study caffeine administration enhances memory consolidation in humans.Randomized controlled trialHumanActiveNature neuroscience2014
Borota D, Murray E, Keceli G, et al.
Caffeine induces alveolar apoptosis in the hyperoxia-exposed developing mouse lung.Other primary literatureAnimalActivePediatric research2014
Dayanim S, Lopez B, Maisonet TM, et al.
From epidemiology to pathophysiology: what about caffeine in Alzheimer's disease?ReviewHuman & animalActiveBiochemical Society transactions2014
Flaten V, Laurent C, Coelho JE, et al.
Energy drink consumption and impact on caffeine risk.Other primary literatureHumanActiveFood additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment2014
Thomson BM, Campbell DM, Cressey P, et al.
Naturalistic Effects of Five Days of Bedtime Caffeine Use on Sleep, Next-Day Cognitive Performance, and Mood.Other primary literatureUnknownActiveJournal of caffeine research2014
Keenan EK, Tiplady B, Priestley CM, et al.
Effect of Caffeine Chronically Consumed During Pregnancy on Adenosine A1 and A2A Receptors Signaling in Both Maternal and Fetal Heart from Wistar Rats.Other primary literatureUnknownActiveJournal of caffeine research2014
Iglesias I, Albasanz JL, Martín M
High CYP2A6 enzyme activity as measured by a caffeine test and unique distribution of CYP2A6 variant alleles in Ethiopian population.Other primary literatureHumanActiveOmics : a journal of integrative biology2014
Aklillu E, Djordjevic N, Carrillo JA, et al.
Fatal caffeine intoxication: a series of eight cases from 1999 to 2009.Other primary literatureHumanActiveJournal of forensic sciences2014
Banerjee P, Ali Z, Levine B, et al.
"Wired," yet intoxicated: modeling binge caffeine and alcohol co-consumption in the mouse.Other primary literatureAnimalActiveAlcoholism, clinical and experimental research2014
Fritz BM, Companion M, Boehm SL
Excess caffeine exposure impairs eye development during chick embryogenesis.Other primary literatureAnimalActiveJournal of cellular and molecular medicine2014
Ma ZL, Wang G, Cheng X, et al.
Relationship between plasma total homocysteine level and dietary caffeine and vitamin B6 intakes in pregnant women.Other primary literatureHumanActiveNursing & health sciences2014
Shiraishi M, Haruna M, Matsuzaki M, et al.
Cumulative neurobehavioral and physiological effects of chronic caffeine intake: individual differences and implications for the use of caffeinated energy products.ReviewHumanActiveNutrition reviews2014
Spaeth AM, Goel N, Dinges DF
Caffeine exposure alters cardiac gene expression in embryonic cardiomyocytes.Other primary literatureAnimalActiveAmerican journal of physiology. Regulatory, integrative and comparative physiology2014
Fang X, Mei W, Barbazuk WB, et al.
Quercetin significantly inhibits the metabolism of caffeine, a substrate of cytochrome P450 1A2 unrelated to CYP1A2*1C (-2964G>A) and *1F (734C>A) gene polymorphisms.Other primary literatureHumanActiveBioMed research international2014
Xiao J, Huang WH, Peng JB, et al.
Development and characterization of polyphenon 60 and caffeine microemulsion for enhanced antibacterial activity.Other primary literatureAnimalActiveBioMed research international2014
Gupta S, Bansal R, Ali J, et al.
Safety profile comparison between extemporaneous and a licensed preparation of caffeine citrate in preterm infants with apnea of prematurity.Other primary literatureHumanActiveNeonatology2014
Vatlach S, Arand J, Engel C, et al.
Long-term effects of caffeine therapy for apnea of prematurity on sleep at school age.Randomized controlled trialHumanActiveAmerican journal of respiratory and critical care medicine2014
Marcus CL, Meltzer LJ, Roberts RS, et al.
Use of a fixed combination of acetylsalicylic acid, acetaminophen and caffeine compared with acetaminophen alone in episodic tension-type headache: meta-analysis of four randomized, double-blind, placebo-controlled, crossover studies.Meta-analysisHumanActiveThe journal of headache and pain2014
Diener HC, Gold M, Hagen M
"Clozapine makes me quite drowsy, so when I wake up in the morning those first cups of coffee are really handy": an exploratory qualitative study of excessive caffeine consumption among individuals with schizophrenia.Other primary literatureHumanActiveBMC psychiatry2014
Thompson L, Pennay A, Zimmermann A, et al.
Effects of carbohydrate combined with caffeine on repeated sprint cycling and agility performance in female athletes.Other primary literatureUnknownActiveJournal of the International Society of Sports Nutrition2014
Lee CL, Cheng CF, Astorino TA, et al.
Preconception care: caffeine, smoking, alcohol, drugs and other environmental chemical/radiation exposure.Meta-analysisHumanActiveReproductive health2014
Lassi ZS, Imam AM, Dean SV, et al.
Maternal caffeine intake during pregnancy is associated with risk of low birth weight: a systematic review and dose-response meta-analysis.Meta-analysisHumanActiveBMC medicine2014
Chen LW, Wu Y, Neelakantan N, et al.
Fatal caffeine overdose and other risks from dietary supplements.Other primary literatureHumanActiveCurrent sports medicine reports2014
Eichner ER
Embryonic caffeine exposure acts via A1 adenosine receptors to alter adult cardiac function and DNA methylation in mice.Other primary literatureAnimalCorrectedPloS one2014
Buscariollo DL, Fang X, Greenwood V, et al.
Caffeine and rolipram affect Smad signalling and TGF-β1 stimulated CTGF and transgelin expression in lung epithelial cells.Other primary literatureHumanActivePloS one2014
Fehrholz M, Speer CP, Kunzmann S
Phenotype refinement strengthens the association of AHR and CYP1A1 genotype with caffeine consumption.Other primary literatureHumanActivePloS one2014
McMahon G, Taylor AE, Davey Smith G, et al.
Trends in caffeine intake among U.S. children and adolescents.Other primary literatureHumanActivePediatrics2014
Branum AM, Rossen LM, Schoendorf KC
Cardiovascular responses to caffeine by gender and pubertal stage.Randomized controlled trialHumanActivePediatrics2014
Temple JL, Ziegler AM, Graczyk A, et al.
Influence of caffeine and hyaluronic acid on collagen biosynthesis in human skin fibroblasts.Other primary literatureHumanActiveDrug design, development and therapy2014
Donejko M, Przylipiak A, Rysiak E, et al.
Caffeine intoxication successfully treated by hemoperfusion and hemodialysis.Other primary literatureHumanActiveInternal medicine (Tokyo, Japan)2014
Ishigaki S, Fukasawa H, Kinoshita-Katahashi N, et al.
Caffeine and suicide: a systematic review.Systematic reviewHumanActiveCNS & neurological disorders drug targets2014
Silva AC, de Oliveira Ribeiro NP, de Mello Schier AR, et al.
Caffeine modifies blood glucose availability during prolonged low-intensity exercise in individuals with type-2 diabetes.Other primary literatureHumanActiveColombia medica (Cali, Colombia)2014
da Silva LA, de Freitas L, Medeiros TE, et al.
Improvements in concentration, working memory and sustained attention following consumption of a natural citicoline-caffeine beverage.Randomized controlled trialHumanActiveInternational journal of food sciences and nutrition2014
Bruce SE, Werner KB, Preston BF, et al.
Caffeinated alcohol use and expectancies for caffeine versus alcohol.Other primary literatureHumanActiveSubstance use & misuse2014
Lau-Barraco C, Linden AN
Coffee, caffeine, and risk of completed suicide: results from three prospective cohorts of American adults.Other primary literatureHumanActiveThe world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry2014
Lucas M, O'Reilly EJ, Pan A, et al.
Effects of caffeine or RX821002 in rats with a neonatal ventral hippocampal lesion.Other primary literatureUnknownActiveFrontiers in behavioral neuroscience2014
Sandner G, Angst MJ, Guiberteau T, et al.
Combination ergotamine and caffeine improves seated blood pressure and presyncopal symptoms in autonomic failure.Other primary literatureUnknownActiveFrontiers in physiology2014
Arnold AC, Ramirez CE, Choi L, et al.
Caffeine intake in children in the United States and 10-y trends: 2001-2010.Other primary literatureHumanActiveThe American journal of clinical nutrition2014
Ahluwalia N, Herrick K, Moshfegh A, et al.
Caffeine-containing energy drinks: beginning to address the gaps in what we know.Other primary literatureHumanActiveAdvances in nutrition (Bethesda, Md.)2014
Sorkin BC, Coates PM
Caffeine and alcohol intakes and overall nutrient adequacy are associated with longitudinal cognitive performance among U.S. adults.Other primary literatureHumanActiveThe Journal of nutrition2014
Beydoun MA, Gamaldo AA, Beydoun HA, et al.
Beverages Of Daily Life: Impact Of Caffeine On Atrial Fibrillation.Other primary literatureUnknownActiveJournal of atrial fibrillation2014
Vittoria Mattioli Md PhD Facc Fesc A
Protective effect of caffeine on ethyl methanesulfonate-induced wing primordial cells of Drosophila melanogaster.Other primary literatureUnknownActiveToxicology international2014
Prakash G, Hosetti BB, Dhananjaya BL
Caffeine and the analog CGS 15943 inhibit cancer cell growth by targeting the phosphoinositide 3-kinase/Akt pathway.Other primary literatureHumanActiveCancer biology & therapy2014
Edling CE, Selvaggi F, Ghonaim R, et al.
Comparison of Caffeine and d-amphetamine in Cocaine-Dependent Subjects: Differential Outcomes on Subjective and Cardiovascular Effects, Reward Learning, and Salivary Paraxanthine.Other primary literatureUnknownActiveJournal of addiction research & therapy2014
Lane SD, Green CE, Schmitz JM, et al.
[Designer drugs and caffeine - characteristics of psychoactive substances and their impact on the organism].ReviewHumanActiveDevelopmental period medicine2014
Wierzejska R
[Comparison of caffeine citrate and aminophylline for treating primary apnea in premature infants].Other primary literatureHumanActiveZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2014
Xu JL, Wang RQ, Chen DM
Acute caffeine poisoning resulting in atrial fibrillation after guarana extract overdose.Other primary literatureHumanActivePrzeglad lekarski2014
Ciszowski K, Biedroń W, Gomólka E
Prenatal and developmental toxicity study of meclizine and caffeine combination in female albino Wistar rats.Other primary literatureAnimalActiveIndian journal of experimental biology2014
Sandeep M, Alvin JM
Characteristics of caffeine intoxication-related death in Tokyo, Japan, between 2008 and 2013.Other primary literatureHumanActiveNihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence2014
Suzuki H, Tanifuji T, Abe N, et al.
Use of Taguchi methodology to enhance the yield of caffeine removal with growing cultures of Pseudomonas pseudoalcaligenes.Other primary literatureUnknownActiveIranian journal of microbiology2014
Ashengroph M, Ababaf S
Energy drinks and caffeine-related adverse effects.Other primary literatureHumanActiveJAMA2013
Sepkowitz KA
Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcome.Systematic reviewHumanUpdatedThe Cochrane database of systematic reviews2013
Jahanfar S, Jaafar SH
Assessment of the ergogenic effect of caffeine supplementation on mood, anticipation timing, and muscular strength in older adults.Other primary literatureUnknownActivePhysiological reports2013
Tallis J, Duncan MJ, Wright SL, et al.
Caffeine can decrease subjective energy depending on the vehicle with which it is consumed and when it is measured.Randomized controlled trialHumanActivePsychopharmacology2013
Young HA, Benton D
Maternal caffeine administration leads to adverse effects on adult mice offspring.Other primary literatureAnimalActiveEuropean journal of nutrition2013
Serapiao-Moraes DF, Souza-Mello V, Aguila MB, et al.
Chronic caffeine intake reverses age-induced insulin resistance in the rat: effect on skeletal muscle Glut4 transporters and AMPK activity.Other primary literatureAnimalActiveAge (Dordrecht, Netherlands)2013
Guarino MP, Ribeiro MJ, Sacramento JF, et al.
Cardiovascular safety of anagrelide in healthy subjects: effects of caffeine and food intake on pharmacokinetics and adverse reactions.Randomized controlled trialHumanActiveClinical drug investigation2013
Martínez-Sellés M, Datino T, Figueiras-Graillet L, et al.
Degradation of caffeine by photo-Fenton process: optimization of treatment conditions using experimental design.Other primary literatureUnknownActiveChemosphere2013
Trovó AG, Silva TF, Gomes O Jr, et al.
Assessing caffeine intake in the United Kingdom diet.Other primary literatureHumanActiveFood chemistry2013
Fitt E, Pell D, Cole D
Fatal cardiac arrhythmia following voluntary caffeine overdose in an amateur body-builder athlete.Other primary literatureHumanActiveInternational journal of cardiology2013
Poussel M, Kimmoun A, Levy B, et al.
Novel analgesic combination of tramadol, paracetamol, caffeine and taurine in the management of moderate to moderately severe acute low back pain.Other primary literatureUnknownActiveJournal of orthopaedics2013
Madhusudhan SK
Levetiracetam interacts synergistically with nonsteroidal analgesics and caffeine to produce antihyperalgesia in rats.Other primary literatureAnimalActiveThe journal of pain2013
Tomić MA, Micov AM, Stepanović-Petrović RM
Caffeine as an adjuvant therapy to opioids in cancer pain: a randomized, double-blind, placebo-controlled trial.Randomized controlled trialHumanActiveJournal of pain and symptom management2013
Suh SY, Choi YS, Oh SC, et al.
The interactions of caffeine with monoamine oxidase.Other primary literatureHuman & animalActiveLife sciences2013
Petzer A, Pienaar A, Petzer JP
[Severe acute caffeine intoxication. A report of two cases with different outcomes].Other primary literatureHumanActiveMedicina intensiva2013
Fernandez-Miret B, Castaño Ávila S, Maynar Moliner J, et al.
Psychostimulant pharmacological profile of paraxanthine, the main metabolite of caffeine in humans.Other primary literatureHuman & animalActiveNeuropharmacology2013
Orrú M, Guitart X, Karcz-Kubicha M, et al.
Phosphatidylserine and caffeine attenuate postexercise mood disturbance and perception of fatigue in humans.Randomized controlled trialHumanActiveNutrition research (New York, N.Y.)2013
Wells AJ, Hoffman JR, Gonzalez AM, et al.
Conditioned reinforcement and locomotor activating effects of caffeine and ethanol combinations in mice.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior2013
Hilbert ML, May CE, Griffin WC 3rd
Caffeine neuroprotects against dexamethasone-induced anxiety-like behaviour in the Zebrafish (Danio rerio).Other primary literatureAnimalActiveGeneral and comparative endocrinology2013
Khor YM, Soga T, Parhar IS
The combined effects of alcohol, caffeine, and expectancies on subjective experience, impulsivity, and risk-taking.Other primary literatureHumanActiveExperimental and clinical psychopharmacology2013
Heinz AJ, de Wit H, Lilje TC, et al.
Impulsivity and alcohol demand in relation to combined alcohol and caffeine use.Other primary literatureHumanActiveExperimental and clinical psychopharmacology2013
Amlung M, Few LR, Howland J, et al.
The Impact of Caffeine on the Behavioral Effects of Ethanol Related to Abuse and Addiction: A Review of Animal Studies.ReviewUnknownActiveJournal of caffeine research2013
López-Cruz L, Salamone JD, Correa M
Caffeine Withdrawal and Dependence: A Convenience Survey Among Addiction Professionals.Other primary literatureUnknownActiveJournal of caffeine research2013
Budney AJ, Brown PC, Griffiths RR, et al.
Paraxanthine: Connecting Caffeine to Nitric Oxide Neurotransmission.Other primary literatureUnknownActiveJournal of caffeine research2013
Ferré S, Orrú M, Guitart X
Caffeine Use Disorder: A Comprehensive Review and Research Agenda.ReviewUnknownActiveJournal of caffeine research2013
Meredith SE, Juliano LM, Hughes JR, et al.
Caffeine Content Labeling: A Missed Opportunity for Promoting Personal and Public Health.Other primary literatureUnknownActiveJournal of caffeine research2013
Kole J, Barnhill A
Chronic Caffeine Administration Attenuates Vascular Injury-Induced Neointimal Hyperplasia in Rats.Other primary literatureUnknownActiveJournal of caffeine research2013
White RD, Holdaway BB, Moody JD, et al.
Fatal caffeine overdose: a case report and review of literature.ReviewHumanActiveThe American journal of forensic medicine and pathology2013
Jabbar SB, Hanly MG
Adenosine receptor antagonists including caffeine alter fetal brain development in mice.Other primary literatureAnimalActiveScience translational medicine2013
Silva CG, Métin C, Fazeli W, et al.
Survival of a highly toxic dose of caffeine.Other primary literatureHumanActiveBMJ case reports2013
Bioh G, Gallagher MM, Prasad U
Pharmacokinetics of Caffeine following a Single Administration of Coffee Enema versus Oral Coffee Consumption in Healthy Male Subjects.Other primary literatureUnknownActiveISRN pharmacology2013
Teekachunhatean S, Tosri N, Rojanasthien N, et al.
Opioid Mechanism Involvement in the Synergism Produced by the Combination of Diclofenac and Caffeine in the Formalin Model.Other primary literatureUnknownActiveISRN Pain2013
Flores-Ramos JM, Díaz-Reval MI
The role of clomipramine in potentiating the teratogenic effects of caffeine in pregnant rats: a histopathological study.Other primary literatureAnimalActiveTheScientificWorldJournal2013
Nikoui V, Ostadhadi S, Takzare N, et al.
Major components of energy drinks (caffeine, taurine, and guarana) exert cytotoxic effects on human neuronal SH-SY5Y cells by decreasing reactive oxygen species production.Other primary literatureHumanActiveOxidative medicine and cellular longevity2013
Zeidán-Chuliá F, Gelain DP, Kolling EA, et al.
Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study.Other primary literatureHumanActiveBMC medicine2013
Sengpiel V, Elind E, Bacelis J, et al.
The effects of caffeine, nicotine, ethanol, and tetrahydrocannabinol on exercise performance.Other primary literatureUnknownActiveNutrition & metabolism2013
Pesta DH, Angadi SS, Burtscher M, et al.
Neuromuscular responses to incremental caffeine doses: performance and side effects.Randomized controlled trialHumanActiveMedicine and science in sports and exercise2013
Pallarés JG, Fernández-Elías VE, Ortega JF, et al.
The effects of caffeine on sleep and maturational markers in the rat.Other primary literatureAnimalActivePloS one2013
Olini N, Kurth S, Huber R
Behavioral and physiologic adverse effects in adolescent and young adult emergency department patients reporting use of energy drinks and caffeine.Other primary literatureHumanActiveClinical toxicology (Philadelphia, Pa.)2013
Jackson DA, Cotter BV, Merchant RC, et al.
Potential toxicity of caffeine when used as a dietary supplement for weight loss.Other primary literatureHumanActiveJournal of dietary supplements2013
Pendleton M, Brown S, Thomas CM, et al.
Caffeine and cognitive decline in elderly women at high vascular risk.Randomized controlled trialHumanActiveJournal of Alzheimer's disease : JAD2013
Vercambre MN, Berr C, Ritchie K, et al.
Pentoxifylline-induced drug rash with eosinophilia and systemic symptoms (DRESS) in a patient with caffeine intolerance.Other primary literatureUnknownActiveJournal of dermatological case reports2013
Saunderson RB, Garsia R, Headley AP, et al.
Caffeine inhibits acetylcholinesterase, but not butyrylcholinesterase.Other primary literatureHumanActiveInternational journal of molecular sciences2013
Pohanka M, Dobes P
Nrf2 and Snail-1 in the prevention of experimental liver fibrosis by caffeine.Other primary literatureAnimalActiveWorld journal of gastroenterology2013
Gordillo-Bastidas D, Oceguera-Contreras E, Salazar-Montes A, et al.
Long-term alcohol and caffeine intake and risk of sudden cardiac death in women.Randomized controlled trialHumanActiveThe American journal of clinical nutrition2013
Bertoia ML, Triche EW, Michaud DS, et al.
Effect of Casilan(®) on (13)C-caffeine metabolism in overnight-fasted healthy Nigerian children.Other primary literatureUnknownActiveJournal of pharmacology & pharmacotherapeutics2013
Oshikoya KA, Smith K
Elevated Norepinephrine may be a Unifying Etiological Factor in the Abuse of a Broad Range of Substances: Alcohol, Nicotine, Marijuana, Heroin, Cocaine, and Caffeine.ReviewUnknownActiveSubstance abuse : research and treatment2013
Fitzgerald PJ
Caffeine attenuates lipid accumulation via activation of AMP-activated protein kinase signaling pathway in HepG2 cells.Other primary literatureHumanActiveBMB reports2013
Quan HY, Kim DY, Chung SH
Caffeine effects on sleep taken 0, 3, or 6 hours before going to bed.Randomized controlled trialHumanActiveJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2013
Drake C, Roehrs T, Shambroom J, et al.
Apnea of prematurity: caffeine dose optimization.Other primary literatureUnknownActiveThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG2013
Francart SJ, Allen MK, Stegall-Zanation J
Protective effect of caffeine against high sugar-induced transcription of microRNAs and consequent gene silencing: a study using lenses of galactosemic mice.Other primary literatureHuman & animalActiveMolecular vision2013
Varma SD, Kovtun S
Is caffeine consumption safe during pregnancy?Other primary literatureHumanActiveCanadian family physician Medecin de famille canadien2013
Morgan S, Koren G, Bozzo P
Protective effects of subchronic caffeine administration on cisplatin induced urogenital toxicity in male mice.Other primary literatureAnimalActiveIndian journal of experimental biology2013
Nasri H
Reduction of facial redness with resveratrol added to topical product containing green tea polyphenols and caffeine.Other primary literatureHumanActiveJournal of drugs in dermatology : JDD2013
Ferzli G, Patel M, Phrsai N, et al.
Double-blind placebo and active (caffeine) controlled study to examine the effects of the herbal nutritional supplement beverage "Wake up" on vigilance and function after lunch.Other primary literatureHumanActiveThe Israel Medical Association journal : IMAJ2013
Kassis O, Katz N, Ravid S, et al.
Caffeine as an analgesic adjuvant for acute pain in adults.Meta-analysisHumanActiveThe Cochrane database of systematic reviews2012
Derry CJ, Derry S, Moore RA
Influence of caffeine on the survival of leaf-cutting ants Atta sexdens rubropilosa and in vitro growth of their mutualistic fungus.Other primary literatureAnimalActivePest management science2012
Miyashira CH, Tanigushi DG, Gugliotta AM, et al.
Effects of caffeine on alcohol-related changes in behavioural control and perceived intoxication in light caffeine consumers.Randomized controlled trialHumanActivePsychopharmacology2012
Attwood AS, Rogers PJ, Ataya AF, et al.
Risk of caffeine toxicity associated with the use of 'legal highs' (novel psychoactive substances).Other primary literatureHumanActiveEuropean journal of clinical pharmacology2012
Davies S, Lee T, Ramsey J, et al.
Comparison of tolerability and efficacy of a combination of paracetamol + caffeine and sumatriptan in the treatment of migraine attack: a randomized, double-blind, double-dummy, cross-over study.Randomized controlled trialHumanActiveThe journal of headache and pain2012
Pini LA, Guerzoni S, Cainazzo M, et al.
Recommendations regarding dietary intake and caffeine and alcohol consumption in patients with cardiac arrhythmias: what do you tell your patients to do or not to do?Other primary literatureUnknownActiveCurrent treatment options in cardiovascular medicine2012
Glatter KA, Myers R, Chiamvimonvat N
Death by caffeine: presumptive malicious poisoning of a dog by incorporation in ground meat.Other primary literatureAnimalActiveJournal of medical toxicology : official journal of the American College of Medical Toxicology2012
Tawde SN, Puschner B, Albin T, et al.
Combined butalbital/acetaminophen/caffeine overdose: case files of the Robert Wood Johnson Medical School Toxicology Service.ReviewHumanActiveJournal of medical toxicology : official journal of the American College of Medical Toxicology2012
Bryczkowski C, Geib AJ
Caffeine increases the motivation to obtain non-drug reinforcers in rats.Other primary literatureAnimalActiveDrug and alcohol dependence2012
Brianna Sheppard A, Gross SC, Pavelka SA, et al.
Caffeine prevents acute mortality after TBI in rats without increased morbidity.Other primary literatureAnimalActiveExperimental neurology2012
Lusardi TA, Lytle NK, Szybala C, et al.
Delayed caffeine treatment prevents nigral dopamine neuron loss in a progressive rat model of Parkinson's disease.Other primary literatureAnimalActiveExperimental neurology2012
Sonsalla PK, Wong LY, Harris SL, et al.
Caffeine interferes embryonic development through over-stimulating serotonergic system in chicken embryo.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2012
Li XD, He RR, Qin Y, et al.
Caffeine increases psychomotor performance on the effort expenditure for rewards task.Other primary literatureHumanActivePharmacology, biochemistry, and behavior2012
Wardle MC, Treadway MT, de Wit H
Caffeine-induced fetal rat over-exposure to maternal glucocorticoid and histone methylation of liver IGF-1 might cause skeletal growth retardation.Other primary literatureAnimalActiveToxicology letters2012
Tan Y, Liu J, Deng Y, et al.
Caffeine in the treatment of pain.ReviewHumanActiveRevista brasileira de anestesiologia2012
Tavares C, Sakata RK
Common psychiatric disorders and caffeine use, tolerance, and withdrawal: an examination of shared genetic and environmental effects.Other primary literatureHumanActiveTwin research and human genetics : the official journal of the International Society for Twin Studies2012
Bergin JE, Kendler KS
Initial development of a measure of expectancies for combinations of alcohol and caffeine: the Caffeine + Alcohol Combined Effects Questionnaire (CACEQ).Other primary literatureHumanActiveExperimental and clinical psychopharmacology2012
MacKillop J, Howland J, Rohsenow DJ, et al.
Arachidonic acid enhances caffeine-induced cell death via caspase-independent cell death.Other primary literatureHumanActiveScientific reports2012
Kuwayama H
Espresso coffees, caffeine and chlorogenic acid intake: potential health implications.Other primary literatureHumanActiveFood & function2012
Crozier TW, Stalmach A, Lean ME, et al.
Effects of caffeine on time trial performance in sedentary men.Other primary literatureHumanActiveJournal of sports sciences2012
Laurence G, Wallman K, Guelfi K
The Effects of Dietary Caffeine Use and Abstention on Blood Oxygen Level-Dependent Activation and Cerebral Blood Flow.Other primary literatureUnknownActiveJournal of caffeine research2012
Addicott MA, Peiffer AM, Laurienti PJ
Pilot Study of Caffeine Abstinence for Control of Chronic Glucose in Type 2 Diabetes.Other primary literatureUnknownActiveJournal of caffeine research2012
Lane JD, Lane AJ, Surwit RS, et al.
Caffeine Enhances Heart Rate Variability in Middle-Aged Healthy, But Not Heart Failure Subjects.Other primary literatureUnknownActiveJournal of caffeine research2012
Notarius CF, Floras JS
Differential Effect of Caffeine Consumption on Diverse Brain Areas of Pregnant Rats.Other primary literatureUnknownActiveJournal of caffeine research2012
Ballesteros-Yáñez I, Castillo CA, Amo-Salas M, et al.
Combined Effects of Ephedrine-Containing Dietary Supplements, Caffeine, and Nicotine on Morphology and Ultrastructure of Rat Hearts.Other primary literatureUnknownActiveJournal of caffeine research2012
Brown CE, Trauth SE, Grippo RS, et al.
Haemodialysis in massive caffeine intoxication.Other primary literatureUnknownActiveClinical kidney journal2012
Fausch K, Uehlinger DE, Jakob S, et al.
Storm in a coffee cup: caffeine modifies brain activation to social signals of threat.Other primary literatureHumanActiveSocial cognitive and affective neuroscience2012
Smith JE, Lawrence AD, Diukova A, et al.
PharmGKB summary: caffeine pathway.Other primary literatureHumanActivePharmacogenetics and genomics2012
Thorn CF, Aklillu E, McDonagh EM, et al.
Role of p53-dependent placental apoptosis in the reproductive and developmental toxicities of caffeine in rodents.Other primary literatureAnimalActiveClinical and experimental pharmacology & physiology2012
Huang J, Zhou S, Ping J, et al.
Maternal hypoxia and caffeine exposure depress fetal cardiovascular function during primary organogenesis.Other primary literatureAnimalActiveThe journal of obstetrics and gynaecology research2012
Momoi N, Tinney JP, Keller BB, et al.
Combined effects of THC and caffeine on working memory in rats.Other primary literatureAnimalActiveBritish journal of pharmacology2012
Panlilio LV, Ferré S, Yasar S, et al.
Caffeine provokes adverse interactions with 3,4-methylenedioxymethamphetamine (MDMA, 'ecstasy') and related psychostimulants: mechanisms and mediators.ReviewHuman & animalActiveBritish journal of pharmacology2012
Vanattou-Saïfoudine N, McNamara R, Harkin A
Dopamine D1 receptor-mediated intracellular responses in the hypothalamus after co-administration of caffeine with MDMA.Other primary literatureAnimalActiveBasic & clinical pharmacology & toxicology2012
Vanattou-Saïfoudine N, Behan B, Harkin A
The aminoglycoside antibiotic kanamycin damages DNA bases in Escherichia coli: caffeine potentiates the DNA-damaging effects of kanamycin while suppressing cell killing by ciprofloxacin in Escherichia coli and Bacillus anthracis.Other primary literatureUnknownActiveAntimicrobial agents and chemotherapy2012
Kang TM, Yuan J, Nguyen A, et al.
Catechins and Caffeine Inhibit Fat Accumulation in Mice through the Improvement of Hepatic Lipid Metabolism.Other primary literatureUnknownActiveJournal of obesity2012
Sugiura C, Nishimatsu S, Moriyama T, et al.
Stimulation and inhibition of bacterial growth by caffeine dependent on chloramphenicol and a phenolic uncoupler--a ternary toxicity study using microfluid segment technique.Other primary literatureUnknownActiveJournal of biomedical nanotechnology2012
Cao J, Kürsten D, Schneider S, et al.
The Relationship between caffeine and coffee consumption and exfoliation glaucoma or glaucoma suspect: a prospective study in two cohorts.Other primary literatureHumanActiveInvestigative ophthalmology & visual science2012
Pasquale LR, Wiggs JL, Willett WC, et al.
Toxicological effects of a mixture used in weight loss products: p-synephrine associated with ephedrine, salicin, and caffeine.Other primary literatureAnimalActiveInternational journal of toxicology2012
Schmitt GC, Arbo MD, Lorensi AL, et al.
Caffeine extends life span, improves healthspan, and delays age-associated pathology in Caenorhabditis elegans.Other primary literatureUnknownActiveLongevity & healthspan2012
Sutphin GL, Bishop E, Yanos ME, et al.
Caffeine for treatment of Parkinson disease: a randomized controlled trial.Randomized controlled trialHumanCorrectedNeurology2012
Postuma RB, Lang AE, Munhoz RP, et al.
A randomized, controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine (Tylenol 3) after outpatient breast surgery.Randomized controlled trialHumanActiveAnnals of surgical oncology2012
Mitchell A, McCrea P, Inglis K, et al.
Exploring the caffeine-induced teratogenicity on neurodevelopment using early chick embryo.Other primary literatureAnimalCorrectedPloS one2012
Ma ZL, Qin Y, Wang G, et al.
Caffeine-induced activated glucocorticoid metabolism in the hippocampus causes hypothalamic-pituitary-adrenal axis inhibition in fetal rats.Other primary literatureAnimalActivePloS one2012
Xu D, Zhang B, Liang G, et al.
Spectral analysis of naturally occurring methylxanthines (theophylline, theobromine and caffeine) binding with DNA.Other primary literatureUnknownActivePloS one2012
Johnson IM, Prakash H, Prathiba J, et al.
Spontaneous abortion and a diet drug containing caffeine and ephedrine: a study within the Danish national birth cohort.Other primary literatureHumanActivePloS one2012
Howards PP, Hertz-Picciotto I, Bech BH, et al.
Synergistic effect of caffeine and glucocorticoids on expression of surfactant protein B (SP-B) mRNA.Other primary literatureHumanActivePloS one2012
Fehrholz M, Bersani I, Kramer BW, et al.
Efficacy and tolerability of combined dipyrone, isometheptene and caffeine in the treatment of mild-to-moderate primary headache episodes.Randomized controlled trialHumanActiveExpert review of neurotherapeutics2012
de Souza Carvalho D, Barea LM, Kowacs PA, et al.
Caffeine treatment disturbs the angiogenesis of zebrafish embryos.Other primary literatureAnimalActiveDrug and chemical toxicology2012
Yeh CH, Liao YF, Chang CY, et al.
Potential toxicity of caffeine when used as a dietary supplement for weight loss.Other primary literatureHumanActiveJournal of dietary supplements2012
Pendleton M, Brown S, Thomas C, et al.
Caffeine in bronchiolitis associated apnea: A retrospective cohort study.Other primary literatureUnknownActiveJournal of pediatric intensive care2012
Duffett M, Liu DM, Deshpande A, et al.
Is caffeine intake associated with urinary incontinence in Japanese adults?Other primary literatureHumanActiveJournal of preventive medicine and public health = Yebang Uihakhoe chi2012
Hirayama F, Lee AH
Effects of caffeine on metabolism and mitochondria biogenesis in rhabdomyosarcoma cells compared with 2,4-dinitrophenol.Other primary literatureUnknownActiveNutrition and metabolic insights2012
Vaughan RA, Garcia-Smith R, Bisoffi M, et al.
Hemodynamic and hematologic profile of healthy adults ingesting dietary supplements containing 1,3-dimethylamylamine and caffeine.Other primary literatureUnknownActiveNutrition and metabolic insights2012
Farney TM, McCarthy CG, Canale RE, et al.
Maternal caffeine consumption has irreversible effects on reproductive parameters and fertility in male offspring rats.Other primary literatureUnknownActiveClinical and experimental reproductive medicine2012
Dorostghoal M, Erfani Majd N, Nooraei P
Effects of morning caffeine' ingestion on mood States, simple reaction time, and short-term maximal performance on elite judoists.Other primary literatureUnknownActiveAsian journal of sports medicine2012
Souissi M, Abedelmalek S, Chtourou H, et al.
Comparison of cosyntropin versus caffeine for post-dural puncture headaches: A randomized double-blind trial.Other primary literatureUnknownActiveWorld journal of emergency medicine2012
Zeger W, Younggren B, Smith L
[Studying toxicity caused by interaction of caffeine and ketorolac].Other primary literatureAnimalActiveEksperimental'naia i klinicheskaia farmakologiia2012
Iudin MA, Kurpiakova AF, Bykov VN, et al.
[Caffeine--common ingredient in a diet and its influence on human health].ReviewHumanActiveRoczniki Panstwowego Zakladu Higieny2012
Wierzejska R
Protective effects of subchronic caffeine administration on cisplatin induced urogenital toxicity in male mice.Other primary literatureAnimalActiveIndian journal of experimental biology2012
Khazaei M, Bayat PD, Ghanbari A, et al.
[Convulsive crisis in Tramadol and caffeine abusers: about 8 cases and review of the literature].ReviewHumanActiveThe Pan African medical journal2012
Maiga DD, Seyni H, Sidikou A, et al.
Coffee, caffeine, and risk of depression among women.Other primary literatureHumanActiveArchives of internal medicine2011
Lucas M, Mirzaei F, Pan A, et al.
Evaluation of the reproductive and developmental risks of caffeine.ReviewHuman & animalActiveBirth defects research. Part B, Developmental and reproductive toxicology2011
Brent RL, Christian MS, Diener RM
Caffeine in Parkinson's disease: a pilot open-label, dose-escalation study.Other primary literatureHumanActiveMovement disorders : official journal of the Movement Disorder Society2011
Altman RD, Lang AE, Postuma RB
Premature chromosome condensation induced by caffeine, 2-aminopurine, staurosporine and sodium metavanadate in S-phase arrested HeLa cells is associated with a decrease in Chk1 phosphorylation, formation of phospho-H2AX and minor cytoskeletal rearrangements.Other primary literatureHumanActiveHistochemistry and cell biology2011
Rybaczek D, Kowalewicz-Kulbat M
From caffeine to fish waste: amine compounds present in food and drugs and their interactions with primary amine oxidase.Other primary literatureHuman & animalActiveJournal of neural transmission (Vienna, Austria : 1996)2011
Olivieri A, Rico D, Khiari Z, et al.
Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells.Other primary literatureHuman & animalActiveMolecules and cells2011
Ku BM, Lee YK, Jeong JY, et al.
Expression of HSP70 in Mytilus californianus following exposure to caffeine.Other primary literatureAnimalActiveEcotoxicology (London, England)2011
del Rey ZR, Granek EF, Buckley BA
Is there a misplaced focus on AmED? Associations between caffeine mixers and bar patron intoxication.Other primary literatureHumanActiveDrug and alcohol dependence2011
Thombs D, Rossheim M, Barnett TE, et al.
A role for adenosine A(1) receptor blockade in the ability of caffeine to promote MDMA "Ecstasy"-induced striatal dopamine release.Other primary literatureAnimalActiveEuropean journal of pharmacology2011
Vanattou-Saïfoudine N, Gossen A, Harkin A
Postmortem measurement of caffeine in bone marrow: influence of sample location and correlation with blood concentration.Other primary literatureHumanActiveForensic science international2011
Cartiser N, Bévalot F, Chatenay C, et al.
Arrhythmogenic Munchausen syndrome culminating in caffeine-induced ventricular tachycardia.Other primary literatureHumanActiveJournal of electrocardiology2011
Vaglio JC, Schoenhard JA, Saavedra PJ, et al.
Investigating the effects of caffeine on phonation.Other primary literatureHumanActiveJournal of voice : official journal of the Voice Foundation2011
Erickson-Levendoski E, Sivasankar M
Caffeine improves attention deficit in neonatal 6-OHDA lesioned rats, an animal model of attention deficit hyperactivity disorder (ADHD).Other primary literatureAnimalActiveNeuroscience letters2011
Caballero M, Núñez F, Ahern S, et al.
Caffeine potentiates methamphetamine-induced toxicity both in vitro and in vivo.Other primary literatureAnimalActiveNeuroscience letters2011
Sinchai T, Plasen S, Sanvarinda Y, et al.
Maternal caffeine intake, blood pressure, and the risk of hypertensive complications during pregnancy. The Generation R Study.Other primary literatureHumanActiveAmerican journal of hypertension2011
Bakker R, Steegers EA, Raat H, et al.
Caffeine and insulin resistance in pregnancy.Other primary literatureHumanActiveAmerican journal of perinatology2011
Laughon SK, Powers RW, Roberts JM, et al.
Creating higher titer lentivirus with caffeine.Other primary literatureHumanActiveHuman gene therapy2011
Ellis BL, Potts PR, Porteus MH
Effects of Caffeine Consumption by Women and Men on the Outcome of In Vitro Fertilization.Other primary literatureUnknownActiveJournal of caffeine research2011
Choi JH, Ryan LM, Cramer DW, et al.
Gender Differences in Subjective and Physiological Responses to Caffeine and the Role of Steroid Hormones.Other primary literatureUnknownActiveJournal of caffeine research2011
Temple JL, Ziegler AM
Alcohol and Caffeine: The Perfect Storm.ReviewUnknownActiveJournal of caffeine research2011
Ferré S, O'Brien MC
Evaluating Dependence Criteria for Caffeine.Other primary literatureUnknownActiveJournal of caffeine research2011
Striley CL, Griffiths RR, Cottler LB
Cognitive slowing associated with elevated serum anticholinergic activity in older individuals is decreased by caffeine use.Other primary literatureHumanActiveThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2011
Nebes RD, Pollock BG, Halligan EM, et al.
Caffeine citrate for very preterm infants: Effects on development, temperament and behaviour.Randomized controlled trialHumanActiveJournal of paediatrics and child health2011
Gray PH, Flenady VJ, Charles BG, et al.
Coffee, ADORA2A, and CYP1A2: the caffeine connection in Parkinson's disease.Other primary literatureHumanActiveEuropean journal of neurology2011
Popat RA, Van Den Eeden SK, Tanner CM, et al.
Artificial sweeteners, caffeine, and alcohol intoxication in bar patrons.Other primary literatureHumanActiveAlcoholism, clinical and experimental research2011
Rossheim ME, Thombs DL
Commentary on Rossheim and Thombs (2011): artificial sweeteners, caffeine, and alcohol intoxication in bar patrons.Other primary literatureHumanActiveAlcoholism, clinical and experimental research2011
Marczinski CA
The efficacy and tolerability of a fixed combination of acetylsalicylic acid, paracetamol, and caffeine in patients with severe headache: a post-hoc subgroup analysis from a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel group study.Randomized controlled trialHumanActiveCephalalgia : an international journal of headache2011
Diener HC, Peil H, Aicher B
Skill execution and sleep deprivation: effects of acute caffeine or creatine supplementation - a randomized placebo-controlled trial.Other primary literatureUnknownActiveJournal of the International Society of Sports Nutrition2011
Cook CJ, Crewther BT, Kilduff LP, et al.
Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.Meta-analysisHumanActivePLoS genetics2011
Cornelis MC, Monda KL, Yu K, et al.
Caffeine acts via A1 adenosine receptors to disrupt embryonic cardiac function.Other primary literatureAnimalActivePloS one2011
Buscariollo DL, Breuer GA, Wendler CC, et al.
Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens.Other primary literatureHuman & animalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2011
Lazarus M, Shen HY, Cherasse Y, et al.
The analgesic and antiemetic efficacy of gabapentin or ergotamine/caffeine for the treatment of postdural puncture headache.Randomized controlled trialHumanActiveAdvances in medical sciences2011
Erol DD
Energy drinks and the neurophysiological impact of caffeine.Other primary literatureUnknownActiveFrontiers in neuroscience2011
Persad LA
Attenuation of cytotoxic natural product DNA intercalating agents by caffeine.Other primary literatureUnknownActiveScientia pharmaceutica2011
Hill GM, Moriarity DM, Setzer WN
Potential activity of the purine compounds caffeine and aminophylline on bacteria.Other primary literatureUnknownActiveJournal of global infectious diseases2011
Al-Janabi AA
Simultaneous activation of salicylate production and fungal resistance in transgenic Chrysanthemum producing caffeine.Other primary literatureUnknownActivePlant signaling & behavior2011
Kim YS, Lim S, Yoda H, et al.
Induction of apoptosis and non-apoptosis in human breast cancer cell line (MCF-7) by cisplatin and caffeine.Other primary literatureHumanActiveIranian biomedical journal2011
Niknafs B
Caffeine versus theophylline for apnea in preterm infants.Meta-analysisHumanActiveThe Cochrane database of systematic reviews2010
Henderson-Smart DJ, Steer PA
Caffeine for asthma.Meta-analysisHumanActiveThe Cochrane database of systematic reviews2010
Welsh EJ, Bara A, Barley E, et al.
Caffeine for the prevention of injuries and errors in shift workers.Meta-analysisHumanActiveThe Cochrane database of systematic reviews2010
Ker K, Edwards PJ, Felix LM, et al.
Caffeine promotes dopamine D1 receptor-mediated body temperature, heart rate and behavioural responses to MDMA ('ecstasy').Other primary literatureAnimalActivePsychopharmacology2010
Vanattou-Saïfoudine N, McNamara R, Harkin A
Genetics of caffeine consumption and responses to caffeine.ReviewHuman & animalActivePsychopharmacology2010
Yang A, Palmer AA, de Wit H
Incidence of caffeine in serum of patients undergoing dipyridamole myocardial perfusion stress test by an intensive versus routine caffeine history screening.Randomized controlled trialHumanActiveThe American journal of cardiology2010
Banko LT, Haq SA, Rainaldi DA, et al.
Nicotine- and caffeine-mediated changes in gene expression patterns of MPTP-lesioned mouse striatum: Implications in neuroprotection mechanism.Other primary literatureAnimalActiveChemico-biological interactions2010
Singh K, Singh S, Singhal NK, et al.
Higher serum caffeine in smokers with schizophrenia compared to smoking controls.Other primary literatureHumanActiveDrug and alcohol dependence2010
Gandhi KK, Williams JM, Menza M, et al.
Patterns of caffeine consumption in psychiatric patients. An Italian study.Other primary literatureHumanActiveEuropean psychiatry : the journal of the Association of European Psychiatrists2010
Ciapparelli A, Paggini R, Carmassi C, et al.
Caffeine protects against combined paraquat and maneb-induced dopaminergic neuron degeneration.Other primary literatureAnimalActiveExperimental neurology2010
Kachroo A, Irizarry MC, Schwarzschild MA
Oxidative stress parameters in rats exposed to fluoride and caffeine.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2010
Inkielewicz-Stepniak I, Czarnowski W
A review of the epidemiologic evidence concerning the reproductive health effects of caffeine consumption: a 2000-2009 update.Other primary literatureHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2010
Peck JD, Leviton A, Cowan LD
Caffeine consumption and miscarriage: a prospective cohort study.Other primary literatureHumanActiveFertility and sterility2010
Pollack AZ, Buck Louis GM, Sundaram R, et al.
Neuroprotection by caffeine: time course and role of its metabolites in the MPTP model of Parkinson's disease.Other primary literatureAnimalActiveNeuroscience2010
Xu K, Xu YH, Chen JF, et al.
Pathophysiological roles for purines: adenosine, caffeine and urate.ReviewHumanActiveProgress in brain research2010
Morelli M, Carta AR, Kachroo A, et al.
Effects of oral caffeine pretreatment on response to intravenous nicotine and cocaine.Randomized controlled trialHumanActiveExperimental and clinical psychopharmacology2010
Johnson MW, Strain EC, Griffiths RR
Association of the anxiogenic and alerting effects of caffeine with ADORA2A and ADORA1 polymorphisms and habitual level of caffeine consumption.Randomized controlled trialHumanActiveNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2010
Rogers PJ, Hohoff C, Heatherley SV, et al.
Prevention of oxidative damage to lens by caffeine.Other primary literatureAnimalActiveJournal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics2010
Varma SD, Hegde KR
Effects of paraxanthine and caffeine on sleep, locomotor activity, and body temperature in orexin/ataxin-3 transgenic narcoleptic mice.Other primary literatureAnimalActiveSleep2010
Okuro M, Fujiki N, Kotorii N, et al.
Caffeine-related atrial fibrillation.Other primary literatureHumanActiveAmerican journal of therapeutics2010
Artin B, Singh M, Richeh C, et al.
A case of fatal caffeine poisoning.Other primary literatureHumanActiveActa anaesthesiologica Scandinavica2010
Rudolph T, Knudsen K
Mechanisms mediating the ability of caffeine to influence MDMA ('Ecstasy')-induced hyperthermia in rats.Other primary literatureAnimalActiveBritish journal of pharmacology2010
Vanattou-Saïfoudine N, McNamara R, Harkin A
Caffeine inhibits the viability and osteogenic differentiation of rat bone marrow-derived mesenchymal stromal cells.Other primary literatureAnimalActiveBritish journal of pharmacology2010
Zhou Y, Guan XX, Zhu ZL, et al.
Inhibition of selenite-induced cataract by caffeine.Other primary literatureAnimalActiveActa ophthalmologica2010
Varma SD, Hegde KR, Kovtun S
Physiological effects of caffeine, epigallocatechin-3-gallate, and exercise in overweight and obese women.Randomized controlled trialHumanActiveApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2010
Smith AE, Lockwood CM, Moon JR, et al.
Caffeinol at the receptor level: anti-ischemic effect of N-methyl-D-aspartate receptor blockade is potentiated by caffeine.Other primary literatureAnimalActiveStroke2010
Zhao X, Strong R, Piriyawat P, et al.
Effect of taurine and caffeine on sleep-wake activity in Drosophila melanogaster.Other primary literatureUnknownActiveNature and science of sleep2010
Lin FJ, Pierce MM, Sehgal A, et al.
Alcohol, drugs, caffeine, tobacco, and environmental contaminant exposure: reproductive health consequences and clinical implications.ReviewHumanActiveCritical reviews in toxicology2010
Sadeu JC, Hughes CL, Agarwal S, et al.
Caffeine abstinence: an ineffective and potentially distressing tinnitus therapy.Other primary literatureHumanActiveInternational journal of audiology2010
Claire LS, Stothart G, McKenna L, et al.
Caffeine fatalities--do sales restrictions prevent intentional intoxications?Other primary literatureHumanActiveClinical toxicology (Philadelphia, Pa.)2010
Thelander G, Jönsson AK, Personne M, et al.
Caffeine as a neurostimulant: Two pediatric acquired brain injury cases.Other primary literatureUnknownActiveJournal of pediatric rehabilitation medicine2010
Barrett PJ, Casey EK, Sisung C, et al.
Maternal caffeine intake from coffee and tea, fetal growth, and the risks of adverse birth outcomes: the Generation R Study.Other primary literatureHumanActiveThe American journal of clinical nutrition2010
Bakker R, Steegers EA, Obradov A, et al.
Caffeine consumption during pregnancy and risk of preterm birth: a meta-analysis.Meta-analysisHumanActiveThe American journal of clinical nutrition2010
Maslova E, Bhattacharya S, Lin SW, et al.
Plant vaccination: stimulation of defense system by caffeine production in planta.ReviewAnimalActivePlant signaling & behavior2010
Kim YS, Choi YE, Sano H
Effects of acute supplementation of caffeine on cardiorespiratory responses during endurance running in a hot & humid climate.Randomized controlled trialHumanActiveThe Indian journal of medical research2010
Ping WC, Keong CC, Bandyopadhyay A
Effectiveness of topical caffeine in cataract prevention: studies with galactose cataract.Other primary literatureAnimalActiveMolecular vision2010
Varma SD, Kovtun S, Hegde K
Effect of melatonin and caffeine interaction on caffeine induced oxidative stress and sleep disorders.Other primary literatureAnimalActiveNigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria2010
Obochi GO, Amali OO, Ochalefu DO
Effects of restricted caffeine intake by mother on fetal, neonatal and pregnancy outcome.Systematic reviewHumanUpdatedThe Cochrane database of systematic reviews2009
Jahanfar S, Sharifah H
Caffeine, artificial sweetener, and fluid intake in anorexia nervosa.Other primary literatureHumanActiveThe International journal of eating disorders2009
Marino JM, Ertelt TE, Wonderlich SA, et al.
Caffeine consumption among eating disorder patients: epidemiology, motivations, and potential of abuse.Other primary literatureHumanActiveEating and weight disorders : EWD2009
Burgalassi A, Ramacciotti CE, Bianchi M, et al.
Effects of chronic caffeine exposure on adenosinergic modulation of the discriminative-stimulus effects of nicotine, methamphetamine, and cocaine in rats.Other primary literatureAnimalActivePsychopharmacology2009
Justinova Z, Ferré S, Barnes C, et al.
Methodological considerations for the quantification of self-reported caffeine use.Other primary literatureHumanActivePsychopharmacology2009
Addicott MA, Yang LL, Peiffer AM, et al.
Caffeine in pregnancy.ReviewHumanActiveArchives of gynecology and obstetrics2009
Kuczkowski KM
Impact of serum caffeine monitoring on adverse effects and chemotherapeutic responses to caffeine-potentiated chemotherapy for osteosarcoma.Other primary literatureHumanActiveJournal of orthopaedic science : official journal of the Japanese Orthopaedic Association2009
Hayashi K, Tsuchiya H, Yamamoto N, et al.
Treatment of cardiovascular collapse from caffeine overdose with lidocaine, phenylephrine, and hemodialysis.Other primary literatureHumanActiveThe American journal of emergency medicine2009
Kapur R, Smith MD
Caffeine for the management of apnea in preterm infants.Other primary literatureUnknownActiveInternational health2009
Mueni E, Opiyo N, English M
Reciprocal roles between caffeine and estrogen on bone via differently regulating cAMP/PKA pathway: the possible mechanism for caffeine-induced osteoporosis in women and estrogen's antagonistic effects.Other primary literatureHumanActiveMedical hypotheses2009
Zhou Y, Zhu ZL, Guan XX, et al.
Caffeine use in children: what we know, what we have left to learn, and why we should worry.ReviewHumanActiveNeuroscience and biobehavioral reviews2009
Temple JL
Peripartum implications of caffeine intake in pregnancy: is there cause for concern?ReviewHuman & animalActiveRevista espanola de anestesiologia y reanimacion2009
Kuczkowski KM
Effect of caffeine on the anticonvulsant effects of oxcarbazepine, lamotrigine and tiagabine in a mouse model of generalized tonic-clonic seizures.Other primary literatureAnimalActivePharmacological reports : PR2009
Chrościńska-Krawczyk M, Ratnaraj N, Patsalos PN, et al.
Effects of ethanol and caffeine on behavior in C57BL/6 mice in the plus-maze discriminative avoidance task.Other primary literatureAnimalActiveBehavioral neuroscience2009
Gulick D, Gould TJ
ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine.Other primary literatureHumanActiveThe Journal of investigative dermatology2009
Heffernan TP, Kawasumi M, Blasina A, et al.
UVB and caffeine: inhibiting the DNA damage response to protect against the adverse effects of UVB.Other primary literatureHuman & animalActiveThe Journal of investigative dermatology2009
Kerzendorfer C, O'Driscoll M
Sex differences in caffeine neurotoxicity following chronic ethanol exposure and withdrawal.Other primary literatureAnimalActiveAlcohol and alcoholism (Oxford, Oxfordshire)2009
Butler TR, Butler TR, Smith KJ, et al.
Embryonic caffeine exposure induces adverse effects in adulthood.Other primary literatureAnimalActiveFASEB journal : official publication of the Federation of American Societies for Experimental Biology2009
Wendler CC, Busovsky-McNeal M, Ghatpande S, et al.
A case of ventricular tachycardia related to caffeine pretreatment.Other primary literatureHumanActiveThe journal of ECT2009
Cua WL, Pease Campbell JA, Stewart JT
Identification of paraxanthine as the most potent caffeine-derived inhibitor of connective tissue growth factor expression in liver parenchymal cells.Other primary literatureAnimalActiveLiver international : official journal of the International Association for the Study of the Liver2009
Gressner OA, Lahme B, Siluschek M, et al.
In vitro and murine efficacy and toxicity studies of nebulized SCC1, a methylated caffeine-silver(I) complex, for treatment of pulmonary infections.Other primary literatureAnimalActiveAntimicrobial agents and chemotherapy2009
Cannon CL, Hogue LA, Vajravelu RK, et al.
Malignant hypertension and acute aortic dissection associated with caffeine-based ephedra-free dietary supplements: a case report.Other primary literatureUnknownActiveCases journal2009
Ahmed I
Acute caffeine ingestion: clinical features in patients attending the emergency department and Scottish poison centre enquiries between 2000 and 2008.Other primary literatureHumanActiveScottish medical journal2009
Waring WS, Laing WJ, Good AM, et al.
Caffeine impairs myocardial blood flow response to physical exercise in patients with coronary artery disease as well as in age-matched controls.Other primary literatureHumanActivePloS one2009
Namdar M, Schepis T, Koepfli P, et al.
Genome-wide screen of genes required for caffeine tolerance in fission yeast.Other primary literatureUnknownActivePloS one2009
Calvo IA, Gabrielli N, Iglesias-Baena I, et al.
Posterior reversible encephalopathy syndrome after intravenous caffeine for post-lumbar puncture headaches.Other primary literatureHumanActiveAJNR. American journal of neuroradiology2009
Ortiz GA, Bianchi NA, Tiede MP, et al.
Caffeine suppresses amyloid-beta levels in plasma and brain of Alzheimer's disease transgenic mice.Other primary literatureHuman & animalCorrectedJournal of Alzheimer's disease : JAD2009
Cao C, Cirrito JR, Lin X, et al.
[Traumatic brain injuries--effects of alcohol and caffeine on intracranial pressure and cerebral blood flow].Other primary literatureHuman & animalActiveRozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti2009
Bláha M, Vajnerová O, Bednár M, et al.
Coffee, tea, caffeine and risk of breast cancer: a 22-year follow-up.Other primary literatureHumanActiveInternational journal of cancer2008
Ganmaa D, Willett WC, Li TY, et al.
Alcohol-induced retrograde memory impairment in rats: prevention by caffeine.Other primary literatureAnimalActivePsychopharmacology2008
Spinetta MJ, Woodlee MT, Feinberg LM, et al.
Caffeine markedly sensitizes human mesothelioma cell lines to pemetrexed.Other primary literatureHumanActiveCancer chemotherapy and pharmacology2008
Min SH, Goldman ID, Zhao R
Tolerability and efficacy of a combination of paracetamol and caffeine in the treatment of tension-type headache: a randomised, double-blind, double-dummy, cross-over study versus placebo and naproxen sodium.Randomized controlled trialHumanActiveThe journal of headache and pain2008
Pini LA, Del Bene E, Zanchin G, et al.
A novel in vitro metabolomics approach for neurotoxicity testing, proof of principle for methyl mercury chloride and caffeine.Other primary literatureAnimalActiveNeurotoxicology2008
van Vliet E, Morath S, Eskes C, et al.
Movement disorder and neuromuscular change in zebrafish embryos after exposure to caffeine.Other primary literatureAnimalActiveNeurotoxicology and teratology2008
Chen YH, Huang YH, Wen CC, et al.
Protein kinase C inhibitor Gö6976 augments caffeine-induced reversal of chemoresistance to cis-diamminedichloroplatinum-II (CDDP) in a human ovarian cancer model.Other primary literatureHumanActiveGynecologic oncology2008
Qamar L, Davis R, Anwar A, et al.
Association between ADORA2A and DRD2 polymorphisms and caffeine-induced anxiety.Other primary literatureHumanActiveNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2008
Childs E, Hohoff C, Deckert J, et al.
UV-B-induced damage to the lens in vitro: prevention by caffeine.Other primary literatureAnimalActiveJournal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics2008
Varma SD, Hegde KR, Kovtun S
Maternal smoking, alcohol consumption, and caffeine consumption during pregnancy in relation to a son's risk of persistent cryptorchidism: a prospective study in the Child Health and Development Studies cohort, 1959-1967.Other primary literatureHumanActiveAmerican journal of epidemiology2008
Mongraw-Chaffin ML, Cohn BA, Cohen RD, et al.
Use of a prescribed ephedrine/caffeine combination and the risk of serious cardiovascular events: a registry-based case-crossover study.Other primary literatureHumanActiveAmerican journal of epidemiology2008
Hallas J, Bjerrum L, Støvring H, et al.
Chemoprevention of dibenzo[a,l]pyrene transplacental carcinogenesis in mice born to mothers administered green tea: primary role of caffeine.Other primary literatureAnimalActiveCarcinogenesis2008
Castro DJ, Yu Z, Löhr CV, et al.
Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.Other primary literatureAnimalActiveCarcinogenesis2008
Wang R, Dashwood WM, Löhr CV, et al.
Determination of caffeine and sympathomimetic alkaloids in weight loss supplements by high-performance liquid chromatography.Other primary literatureUnknownActiveJournal of chromatographic science2008
Evans RL, Siitonen PH
Caffeine use: association with nicotine use, aggression, and other psychopathology in psychiatric and pediatric outpatient adolescents.Other primary literatureHumanActiveTheScientificWorldJournal2008
Martin CA, Cook C, Woodring JH, et al.
Maternal caffeine intake during pregnancy and risk of fetal growth restriction: a large prospective observational study.Other primary literatureHumanCorrectedBMJ (Clinical research ed.)2008
Modest maternal caffeine exposure affects developing embryonic cardiovascular function and growth.Other primary literatureAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2008
Momoi N, Tinney JP, Liu LJ, et al.
Caffeine consumption and the risk of primary open-angle glaucoma: a prospective cohort study.Other primary literatureHumanActiveInvestigative ophthalmology & visual science2008
Kang JH, Willett WC, Rosner BA, et al.
Protective effect of caffeine on streptozotocin-induced beta-cell damage in rats.Other primary literatureAnimalActiveThe Journal of pharmacy and pharmacology2008
Kagami K, Morita H, Onda K, et al.
Fast inhibition of glutamate-activated currents by caffeine.Other primary literatureAnimalActivePloS one2008
Vyleta NP, Smith SM
Perinatal caffeine, acting on maternal adenosine A(1) receptors, causes long-lasting behavioral changes in mouse offspring.Other primary literatureAnimalActivePloS one2008
Björklund O, Kahlström J, Salmi P, et al.
Caffeine in children with obstructive sleep apnea.Randomized controlled trialHumanActiveMiddle East journal of anaesthesiology2008
Khalil SN, Maposa D, Ghelber O, et al.
[Acute caffeine intoxication after intake of 'herbal energy capsules'].Other primary literatureHumanActiveNederlands tijdschrift voor geneeskunde2008
Kromhout HE, Landstra AM, van Luin M, et al.
[Acute caffeine intoxication after intake of 'herbal energy capsules'].Other primary literatureHumanActiveNederlands tijdschrift voor geneeskunde2008
de Wijkerslooth LR, Koch BC, Malingré MM, et al.
HPLC determination of caffeine and paraxanthine in urine: An assay for cytochrome P450 1A2 activity.Other primary literatureUnknownActiveBiochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology2007
Furge LL, Fletke KJ
Caffeine attenuates practice effects in word stem completion as measured by fMRI BOLD signal.Randomized controlled trialHumanActiveHuman brain mapping2007
Bendlin BB, Trouard TP, Ryan L
Effect of caffeine on microsurgical technical performance.Randomized controlled trialHumanActiveMicrosurgery2007
Urso-Baiarda F, Shurey S, Grobbelaar AO
Caffeine analogs: biomedical impact.ReviewHumanActiveCellular and molecular life sciences : CMLS2007
Daly JW
The enigmatic effects of caffeine in cell cycle and cancer.ReviewHuman & animalActiveCancer letters2007
Bode AM, Dong Z
Caffeine and adenosine A(2a) receptor antagonists prevent beta-amyloid (25-35)-induced cognitive deficits in mice.Other primary literatureAnimalActiveExperimental neurology2007
Dall'Igna OP, Fett P, Gomes MW, et al.
Evaluation of cardiovascular effects of caffeine using telemetric monitoring in the conscious rat.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2007
Ilbäck NG, Siller M, Stålhandske T
Evaluation of Athrixia bush tea for cytotoxicity, antioxidant activity, caffeine content and presence of pyrrolizidine alkaloids.Other primary literatureHuman & animalActiveJournal of ethnopharmacology2007
McGaw LJ, Steenkamp V, Eloff JN
Long-term consumption of caffeine improves glucose homeostasis by enhancing insulinotropic action through islet insulin/insulin-like growth factor 1 signaling in diabetic rats.Other primary literatureAnimalActiveMetabolism: clinical and experimental2007
Park S, Jang JS, Hong SM
The effects of methylmercury on motor activity are sex- and age-dependent, and modulated by genetic deletion of adenosine receptors and caffeine administration.Other primary literatureAnimalActiveToxicology2007
Björklund O, Kahlström J, Salmi P, et al.
Serum caffeine concentrations in preterm neonates.Other primary literatureHumanActiveAmerican journal of perinatology2007
Leon AE, Michienzi K, Ma CX, et al.
Cardiotoxicity of Ma Huang/caffeine or ephedrine/caffeine in a rodent model system.Other primary literatureAnimalActiveToxicologic pathology2007
Dunnick JK, Kissling G, Gerken DK, et al.
Caffeine use by children: the quest for enhancement.Other primary literatureHumanActiveSubstance use & misuse2007
Bramstedt KA
Highly efficient induction of triploid Pacific abalone Haliotis discus hannai by caffeine treatmentOther primary literatureUnknownUnknownFish Sci2007
OKUMURA SI, ARAI K, HARIGAYA Y, et al.
Crossover, double-blind clinical trial comparing almotriptan and ergotamine plus caffeine for acute migraine therapy.Randomized controlled trialHumanActiveEuropean journal of neurology2007
Láinez MJ, Galván J, Heras J, et al.
Efficacy of dosing and re-dosing of two oral fixed combinations of indomethacin, prochlorperazine and caffeine compared with oral sumatriptan in the acute treatment of multiple migraine attacks: a double-blind, double-dummy, randomised, parallel group, multicentre study.Randomized controlled trialHumanActiveInternational journal of clinical practice2007
Sandrini G, Cerbo R, Del Bene E, et al.
Effect of caffeine supplementation on haematological and biochemical variables in elite soccer players under physical stress conditions.Randomized controlled trialHumanActiveBritish journal of sports medicine2007
Bassini-Cameron A, Sweet E, Bottino A, et al.
Effect of reducing caffeine intake on birth weight and length of gestation: randomised controlled trial.Randomized controlled trialHumanActiveBMJ (Clinical research ed.)2007
Bech BH, Obel C, Henriksen TB, et al.
Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin, and green tea.ReviewHuman & animalActiveAmerican journal of physiology. Regulatory, integrative and comparative physiology2007
Diepvens K, Westerterp KR, Westerterp-Plantenga MS
Effects of dietary caffeine on topographic EEG after controlling for withdrawal and withdrawal reversal.Randomized controlled trialHumanActiveNeuropsychobiology2007
Keane MA, James JE, Hogan MJ
Efficacy of a paracetamol and caffeine combination in the treatment of the key symptoms of primary dysmenorrhoea.Randomized controlled trialHumanActiveCurrent medical research and opinion2007
Ali Z, Burnett I, Eccles R, et al.
[Caffeine: a nutrient, a drug or a drug of abuse].ReviewHumanActiveAdicciones2007
Pardo Lozano R, Alvarez García Y, Barral Tafalla D, et al.
Effects of acute caffeine withdrawal on Short Category Test performance in sleep-deprived individuals.Randomized controlled trialHumanActivePerceptual and motor skills2007
Killgore WD, Kahn-Greene ET, Killgore DB, et al.
Synthesis and brain antihypoxic activity of some aliphatic and arylaliphatic amides of caffeine-8-thioglycolic acid.Other primary literatureAnimalActiveActa pharmaceutica (Zagreb, Croatia)2007
Mitkov J, Danchev N, Nikolova I, et al.
Effect of caffeine-coconut products interactions on induction of microsomal drug-metabolizing enzymes in Wistar albino rats.Other primary literatureAnimalActiveNigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria2007
Abara AE, Obochi GO, Malu SP, et al.
Caffeine overdose with rhabdomyolysis and hypokalaemia.Other primary literatureUnknownActiveAcute medicine2007
Chakraborty T, Rajeswaran C
[A brief "update" on renal effects of caffeine].Other primary literatureHumanActiveGiornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia2007
Bolignano D, Coppolino G, Crascì E, et al.
[Case of intractable ventricula fibrillation by a multicomponent dietary supplement containing ephedra and caffeine overdose].Other primary literatureHumanActiveChudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology2007
Takeuchi S, Homma M, Inoue J, et al.
[Caffeine and birth weight--randomised double blind trial].Other primary literatureUnknownActiveUgeskrift for laeger2007
Bech BH, Obel C, Henriksen TB, et al.
Effect of caffeine and alcohol on the toxicity and metabolism of methacrylonitrile in male Sprague-Dawley rats.Other primary literatureAnimalActiveResearch communications in molecular pathology and pharmacology2007
Farooqui MY, Trevino M, Garcia I
Complexation of anthracycline drugs with DNA in the presence of caffeine.Other primary literatureUnknownActiveEuropean biophysics journal : EBJ2006
Evstigneev MP, Khomich VV, Davies DB
[Apnea of prematurity: risk factors and ambulatory treatment with caffeine citrate].Other primary literatureHumanActiveArchives de pediatrie : organe officiel de la Societe francaise de pediatrie2006
Ducrocq S, Biran-Mucignat V, Boelle PY, et al.
Association of caffeine to MDMA does not increase antinociception but potentiates adverse effects of this recreational drug.Other primary literatureAnimalActiveBrain research2006
Camarasa J, Pubill D, Escubedo E
The effects of caffeine on the inducibility of atrial fibrillation.Other primary literatureAnimalActiveJournal of electrocardiology2006
Rashid A, Hines M, Scherlag BJ, et al.
Caffeine promotes hyperthermia and serotonergic loss following co-administration of the substituted amphetamines, MDMA ("Ecstasy") and MDA ("Love").Other primary literatureAnimalActiveNeuropharmacology2006
McNamara R, Kerans A, O'Neill B, et al.
Caffeine intake, toxicity and dependence and lifetime risk for psychiatric and substance use disorders: an epidemiologic and co-twin control analysis.Other primary literatureHumanActivePsychological medicine2006
Kendler KS, Myers J, O Gardner C
Clubgoers and their trendy cocktails: implications of mixing caffeine into alcohol on information processing and subjective reports of intoxication.Other primary literatureHumanActiveExperimental and clinical psychopharmacology2006
Marczinski CA, Fillmore MT
Analysis of diacetylmorphine, caffeine, and degradation products after volatilization of pharmaceutical heroin for inhalation.Other primary literatureHumanActiveJournal of analytical toxicology2006
Klous MG, Lee W, Hillebrand MJ, et al.
Multiple cardiac arrests following an overdose of caffeine complicated by penetrating trauma.Other primary literatureHumanActiveAnaesthesia2006
Emohare O, Ratnam V
Rofecoxib is a potent inhibitor of cytochrome P450 1A2: studies with tizanidine and caffeine in healthy subjects.Randomized controlled trialHumanActiveBritish journal of clinical pharmacology2006
Backman JT, Karjalainen MJ, Neuvonen M, et al.
Effects of a divided high loading dose of caffeine on circulatory variables in preterm infants.Other primary literatureHumanActiveArchives of disease in childhood. Fetal and neonatal edition2006
Hoecker C, Nelle M, Beedgen B, et al.
Comparing attitudes about legal sanctions and teratogenic effects for cocaine, alcohol, tobacco and caffeine: a randomized, independent samples design.Other primary literatureHumanActiveSubstance abuse treatment, prevention, and policy2006
Ginsburg HJ, Raffeld P, Alanis KL, et al.
Estrogen prevents neuroprotection by caffeine in the mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2006
Xu K, Xu Y, Brown-Jermyn D, et al.
Nonlinear dynamics of blood pressure variability after caffeine consumption.Randomized controlled trialHumanActiveClinical medicine & research2006
Papaioannou TG, Vlachopoulos C, Ioakeimidis N, et al.
[Caffeine intoxication: history, clinical features, diagnosis and treatment].ReviewHumanActiveHarefuah2006
Iancu I, Strous RD
Acute exposure to caffeine decreases the anticonvulsant action of ethosuximide, but not that of clonazepam, phenobarbital and valproate against pentetrazole-induced seizures in mice.Other primary literatureAnimalActivePharmacological reports : PR2006
Luszczki JJ, Zuchora M, Sawicka KM, et al.
Effects of caffeine on heart rate and QT variability during sleep.Randomized controlled trialHumanActiveDepression and anxiety2005
Bonnet M, Tancer M, Uhde T, et al.
Effects of caffeine on performance and mood: withdrawal reversal is the most plausible explanation.Meta-analysisHumanActivePsychopharmacology2005
James JE, Rogers PJ
Cognitive and psychomotor performance, mood, and pressor effects of caffeine after 4, 6 and 8 h caffeine abstinence.Randomized controlled trialHumanActivePsychopharmacology2005
Heatherley SV, Hayward RC, Seers HE, et al.
Formation of stacking complexes between caffeine (1,2,3-trimethylxanthine) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine may attenuate biological effects of this neurotoxin.Other primary literatureHuman & animalActiveBioorganic chemistry2005
Ulanowska K, Piosik J, Gwizdek-Wiśniewska A, et al.
Caffeine for reducing bird damage to newly seeded riceOther primary literatureUnknownUnknownCrop Protection2005
Avery ML, Werner SJ, Cummings JL, et al.
Effects of caffeine on placental total nitrite concentration: A 21-day, vehicle-controlled study in rats.Other primary literatureUnknownActiveCurrent therapeutic research, clinical and experimental2005
Alasehirli B, Cekmen M, Nacak M, et al.
Inhibition of human TREK-1 channels by caffeine and theophylline.Other primary literatureHuman & animalActiveEpilepsy research2005
Harinath S, Sikdar SK
Fatal caffeine overdose: two case reports.Other primary literatureHumanActiveForensic science international2005
Kerrigan S, Lindsey T
Effect of coffee on endothelial function in healthy subjects: the role of caffeine.Randomized controlled trialHumanActiveClinical science (London, England : 1979)2005
Papamichael CM, Aznaouridis KA, Karatzis EN, et al.
Reactive blue prevented caffeine-induced neurotoxicity by an independent mechanism from intracellular calcium currents in cell culture from auditory cortex of rats.Other primary literatureAnimalActiveThe International journal of neuroscience2005
Uçüncü H, Bakuridze K, Düzenli S, et al.
Mechanistic pharmacokinetic modelling of ephedrine, norephedrine and caffeine in healthy subjects.Meta-analysisHumanActiveBritish journal of clinical pharmacology2005
Csajka C, Haller CA, Benowitz NL, et al.
Fluvoxamine impairs single-dose caffeine clearance without altering caffeine pharmacodynamics.Randomized controlled trialHumanActiveBritish journal of clinical pharmacology2005
Culm-Merdek KE, von Moltke LL, Harmatz JS, et al.
The fixed combination of acetylsalicylic acid, paracetamol and caffeine is more effective than single substances and dual combination for the treatment of headache: a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel group study.Randomized controlled trialHumanActiveCephalalgia : an international journal of headache2005
Diener HC, Pfaffenrath V, Pageler L, et al.
Enhanced response to caffeine and 4-chloro-m-cresol in malignant hyperthermia-susceptible muscle is related in part to chronically elevated resting [Ca2+]i.Other primary literatureAnimalActiveAmerican journal of physiology. Cell physiology2005
López JR, Linares N, Pessah IN, et al.
Ephedrine plus caffeine causes age-dependent cardiovascular responses in Fischer 344 rats.Other primary literatureAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2005
Howden R, Hanlon PR, Petranka JG, et al.
Methylxanthine therapy for apnea of prematurity: evaluation of treatment benefits and risks at age 5 years in the international Caffeine for Apnea of Prematurity (CAP) trial.ReviewHumanActiveBiology of the neonate2005
Schmidt B
Electrocardiographic and hemodynamic effects of a multicomponent dietary supplement containing ephedra and caffeine: a randomized controlled trial.Randomized controlled trialHumanActiveJAMA2004
McBride BF, Karapanos AK, Krudysz A, et al.
Theophylline, aminophylline, caffeine and analogues for acute ischaemic stroke.Systematic reviewHumanActiveThe Cochrane database of systematic reviews2004
Bath PM
Caffeine as a psychomotor stimulant: mechanism of action.ReviewHuman & animalActiveCellular and molecular life sciences : CMLS2004
Fisone G, Borgkvist A, Usiello A
Enhanced stimulant and metabolic effects of combined ephedrine and caffeine.Randomized controlled trialHumanActiveClinical pharmacology and therapeutics2004
Haller CA, Jacob P 3rd, Benowitz NL
Pharmacokinetic interactions between phenylpropanolamine, caffeine and chlorpheniramine in rats.Other primary literatureAnimalActiveEuropean journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences2004
Kaddoumi A, Nakashima MN, Wada M, et al.
Beverage caffeine intake in US consumers and subpopulations of interest: estimates from the Share of Intake Panel survey.Other primary literatureHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2004
Knight CA, Knight I, Mitchell DC, et al.
Caffeine fatalities--four case reports.Other primary literatureHumanActiveForensic science international2004
Holmgren P, Nordén-Pettersson L, Ahlner J
Caffeine suppresses the expression of the Bcl-2 mRNA in BeWo cell culture and rat placenta.Other primary literatureAnimalActiveThe Journal of nutritional biochemistry2004
Nomura K, Saito S, Ide K, et al.
Protective effect of caffeine against neurodegeneration in a model of Parkinson's disease in rat: behavioral and histochemical evidence.Other primary literatureAnimalActiveParkinsonism & related disorders2004
Joghataie MT, Roghani M, Negahdar F, et al.
Self-injurious behaviour: a comparison of caffeine and pemoline models in rats.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior2004
Kies SD, Devine DP
Effect of a dietary herbal supplement containing caffeine and ephedra on weight, metabolic rate, and body composition.Randomized controlled trialHumanActiveObesity research2004
Greenway FL, De Jonge L, Blanchard D, et al.
A randomized double-blind placebo-controlled clinical trial of a product containing ephedrine, caffeine, and other ingredients from herbal sources for treatment of overweight and obesity in the absence of lifestyle treatment.Randomized controlled trialHumanActiveInternational journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity2004
Coffey CS, Steiner D, Baker BA, et al.
Consequences of smoking and caffeine consumption during pregnancy in women with type 1 diabetes.Other primary literatureHumanActiveThe journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians2004
Khoury JC, Miodovnik M, Buncher CR, et al.
Caffeine reduces cerebral blood flow in patients recovering from an ischaemic stroke.Randomized controlled trialHumanActiveAge and ageing2004
Ragab S, Lunt M, Birch A, et al.
Is caffeine excess part of your differential diagnosis?Other primary literatureHumanActiveThe Nurse practitioner2004
Bridle L, Remick J, Duffy E
High dose caffeine citrate for extubation of preterm infants: a randomised controlled trial.Randomized controlled trialHumanActiveArchives of disease in childhood. Fetal and neonatal edition2004
Steer P, Flenady V, Shearman A, et al.
Developmental effects of propyphenazone in analgesic and antipyretic combination with caffeine or paracetamol.Other primary literatureAnimalActiveHuman & experimental toxicology2004
Burdan F
Caffeine and ephedrine: physiological, metabolic and performance-enhancing effects.ReviewHumanActiveSports medicine (Auckland, N.Z.)2004
Magkos F, Kavouras SA
[Comparison of the effectiveness of lysine acetylsalicylate and metoclopramide combination with ergotamine plus caffeine in the treatment of migraine attacks].Randomized controlled trialHumanActiveWiadomosci lekarskie (Warsaw, Poland : 1960)2004
Stepień A, Kozubski W
Apoptosis induced by different doses of caffeine on Chinese hamster ovary cells.Other primary literatureAnimalActiveJournal of applied toxicology : JAT2003
Fernández MJ, López A, Santa-Maria A
Caffeine enhances myocardial uptake of idarubicin but reverses its negative inotropic effect.Other primary literatureAnimalActiveNaunyn-Schmiedeberg's archives of pharmacology2003
Kang W, Weiss M
Caffeine and human DNA metabolism: the magic and the mystery.Other primary literatureHumanActiveMutation research2003
Kaufmann WK, Heffernan TP, Beaulieu LM, et al.
Caffeine and muscarinic antagonists act in synergy to inhibit haloperidol-induced catalepsy.Other primary literatureAnimalActiveNeuropharmacology2003
Moo-Puc RE, Góngora-Alfaro JL, Alvarez-Cervera FJ, et al.
Caffeine reduces hypnotic effects of alcohol through adenosine A2A receptor blockade.Other primary literatureAnimalActiveNeuropharmacology2003
El Yacoubi M, Ledent C, Parmentier M, et al.
Caffeine consumption in drivers of heavy vehicles in Turkey.Other primary literatureHumanActivePublic health2003
Yildirim RC
Caffeine enhances the expression of the angiotensin II Type 2 receptor mRNA in BeWo cell culture and in the rat placenta.Other primary literatureHuman & animalActivePlacenta2003
Tanuma A, Saito S, Ide I, et al.
Intrauterine growth retardation and lack of teratogenic effects of prenatal exposure to the combination of paracetamol and caffeine in Wistar rats.Other primary literatureAnimalCorrectedReproductive toxicology (Elmsford, N.Y.)2003
Burdan F
Interaction of ibuprofen and probenecid with drug metabolizing enzyme phenotyping procedures using caffeine as the probe drug.Other primary literatureHumanActiveBritish journal of clinical pharmacology2003
Vrtic F, Haefeli WE, Drewe J, et al.
Effects of caffeine on human health.ReviewHumanActiveFood additives and contaminants2003
Nawrot P, Jordan S, Eastwood J, et al.
Massive caffeine overdose requiring vasopressin infusion and hemodialysis.Other primary literatureHumanActiveJournal of toxicology. Clinical toxicology2003
Holstege CP, Hunter Y, Baer AB, et al.
Toxicity of acetaminophen, salicylic acid, and caffeine for first-passage rat renal inner medullary collecting duct cells.Other primary literatureAnimalActiveThe Journal of pharmacology and experimental therapeutics2003
Cai Q, Dmitrieva NI, Michea LF, et al.
Tobacco, coffee, and Parkinson's disease.Other primary literatureUnknownCorrectedBMJ (Clinical research ed.)2003
Gale C, Martyn C
Crossover comparison of efficacy and preference for rizatriptan 10 mg versus ergotamine/caffeine in migraine.Randomized controlled trialHumanActiveEuropean neurology2003
Christie S, Göbel H, Mateos V, et al.
Pilot dose-escalation study of caffeine plus ethanol (caffeinol) in acute ischemic stroke.Other primary literatureHumanActiveStroke2003
Piriyawat P, Labiche LA, Burgin WS, et al.
Caffeine in fertilization medium is not essential for bovine IVF by fully capacitated spermatozoa.Other primary literatureAnimalActiveThe Journal of reproduction and development2003
Momozawa K, Fukuda Y
Alcohol, nicotine, caffeine, and mental disorders.Other primary literatureUnknownActiveDialogues in clinical neuroscience2003
Crocq MA
Interactions between alcohol and caffeine in relation to psychomotor speed and accuracy.Randomized controlled trialHumanActiveHuman psychopharmacology2002
Mackay M, Tiplady B, Scholey AB
Caffeine enhances the calcium-dependent cardiac mitochondrial permeability transition: relevance for caffeine toxicity.Other primary literatureAnimalActiveToxicology and applied pharmacology2002
Sardão VA, Oliveira PJ, Moreno AJ
Effect of caffeine on acetaminophen hepatotoxicity in cultured hepatocytes treated with ethanol and isopentanol.Other primary literatureAnimalActiveToxicology and applied pharmacology2002
DiPetrillo K, Wood S, Kostrubsky V, et al.
Effects of caffeine, sleep loss, and stress on cognitive performance and mood during U.S. Navy SEAL training. Sea-Air-Land.Randomized controlled trialHumanActivePsychopharmacology2002
Lieberman HR, Tharion WJ, Shukitt-Hale B, et al.
Maintaining alertness and performance during sleep deprivation: modafinil versus caffeine.Randomized controlled trialHumanActivePsychopharmacology2002
Wesensten NJ, Belenky G, Kautz MA, et al.
Differences in caffeine and paraxanthine metabolism between human and murine CYP1A2.Other primary literatureHuman & animalActiveBiochemical pharmacology2002
Labedzki A, Buters J, Jabrane W, et al.
Effects of caffeine on development and behavior in infancy and childhood: a review of the published literature.ReviewHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2002
Castellanos FX, Rapoport JL
Caffeine's neuroprotection against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity shows no tolerance to chronic caffeine administration in mice.Other primary literatureAnimalActiveNeuroscience letters2002
Xu K, Xu YH, Chen JF, et al.
Maximum cognitive performance and physiological time trend measurements after caffeine intake.Other primary literatureHumanActiveBrain research. Cognitive brain research2002
Kourtidou-Papadeli C, Papadelis C, Louizos AL, et al.
Herbal ephedra/caffeine for weight loss: a 6-month randomized safety and efficacy trial.Randomized controlled trialHumanActiveInternational journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity2002
Boozer CN, Daly PA, Homel P, et al.
An acute clinical trial evaluating the cardiovascular effects of an herbal ephedra-caffeine weight loss product in healthy overweight adults.Randomized controlled trialHumanActiveInternational journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity2002
Kalman D, Incledon T, Gaunaurd I, et al.
Caffeine in apnoeic Asian neonates: a sparse data analysis.Other primary literatureHumanActiveBritish journal of clinical pharmacology2002
Lee HS, Khoo YM, Chirino-Barcelo Y, et al.
Long-term caffeine consumption exacerbates renal failure in obese, diabetic, ZSF1 (fa-fa(cp)) rats.Other primary literatureAnimalActiveKidney international2002
Tofovic SP, Kost CK Jr, Jackson EK, et al.
Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use.Other primary literatureHumanActiveClinical pharmacology and therapeutics2002
Haller CA, Jacob P 3rd, Benowitz NL
Efficacy, tolerability and safety of oral eletriptan and ergotamine plus caffeine (Cafergot) in the acute treatment of migraine: a multicentre, randomised, double-blind, placebo-controlled comparison.Randomized controlled trialHumanActiveEuropean neurology2002
Diener HC, Jansen JP, Reches A, et al.
Interactions of caffeine and restraint stress during pregnancy in mice.Other primary literatureHuman & animalActiveExperimental biology and medicine (Maywood, N.J.)2002
Albina ML, Colomina MT, Sanchez DJ, et al.
The onset of action and the analgesic efficacy of Saridon (a propyphenazone/paracetamol/ caffeine combination) in comparison with paracetamol, ibuprofen, aspirin and placebo (pooled statistical analysis).Other primary literatureHumanActiveCurrent medical research and opinion2002
Kiersch TA, Minić MR
Known and hidden sources of caffeine in drug, food, and natural products.Other primary literatureHumanActiveJournal of the American Pharmaceutical Association (Washington, D.C. : 1996)2002
Durrant KL
Caffeine induces dopamine and glutamate release in the shell of the nucleus accumbens.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2002
Solinas M, Ferré S, You ZB, et al.
Does caffeine counteract alcohol-induced impairment? The ironic effects of expectancy.Other primary literatureHumanActiveJournal of studies on alcohol2002
Fillmore MT, Roach EL, Rice JT
Caffeine, quercetin and alizarin stimulate the exhalation of metabolic products of [14C]-N-nitrosodiethylamine in mice.Other primary literatureAnimalActiveIndian journal of experimental biology2002
Khanduja KL, Sangari RK, Bhardwaj A
Prophylactic caffeine to prevent postoperative apnea following general anesthesia in preterm infants.Systematic reviewHumanUpdatedThe Cochrane database of systematic reviews2001
Henderson-Smart DJ, Steer P
Effects of caffeine on locomotor activity of horses: determination of the no-effect threshold.Other primary literatureAnimalActiveJournal of applied toxicology : JAT2001
Queiroz-Neto A, Zamur G, Carregaro AB, et al.
Interactions in developmental toxicology: combined action of restraint stress, caffeine, and aspirin in pregnant mice.Other primary literatureAnimalActiveTeratology2001
Colomina MT, Albina ML, Sanchez DJ, et al.
Teratogen update: evaluation of the reproductive and developmental risks of caffeine.ReviewHuman & animalActiveTeratology2001
Christian MS, Brent RL
Caffeine antagonism of alcohol-induced driving impairment.Randomized controlled trialHumanActiveDrug and alcohol dependence2001
Liguori A, Robinson JH
Caffeine intoxication in a premature neonate.Other primary literatureHumanActivePaediatric anaesthesia2001
Ergenekon E, Dalgiç N, Aksoy E, et al.
The safety and efficacy of pharmaceutical and herbal caffeine and ephedrine use as a weight loss agent.ReviewHuman & animalActiveObesity reviews : an official journal of the International Association for the Study of Obesity2001
Greenway FL
Caffeine: The forgotten variable.Other primary literatureUnknownActiveInternational journal of psychiatry in clinical practice2001
Beer CP
Maternal caffeine intake and intrauterine growth retardation.Other primary literatureHumanCorrectedEpidemiology (Cambridge, Mass.)2001
Grosso LM, Rosenberg KD, Belanger K, et al.
Ketoprofen-induced cyclooxygenase inhibition in renal medulla and platelets of rats treated with caffeine.Other primary literatureAnimalActivePharmacology2001
Sommerauer M, Ates M, Gühring H, et al.
Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2001
Chen JF, Xu K, Petzer JP, et al.
Caffeine and exercise: metabolism, endurance and performance.ReviewHumanActiveSports medicine (Auckland, N.Z.)2001
Graham TE
Caffeine citrate: a review of its use in apnoea of prematurity.ReviewHumanActivePaediatric drugs2001
Comer AM, Perry CM, Figgitt DP
Quantitative design of optimal analgesic combination of acetaminophen, caffeine, and butalbital.Other primary literatureAnimalActiveActa pharmacologica Sinica2001
Zheng QS, Wang XW, Gui CQ, et al.
Acute exposure to caffeine selectively disrupts context conditioning in rats.Other primary literatureAnimalActivePsychopharmacology2000
Corodimas KP, Pruitt JC, Stieg JM
Safety and efficacy of treatment with an ephedrine/caffeine mixture. The first double-blind placebo-controlled pilot study in adolescents.Randomized controlled trialHumanActiveInternational journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity2000
Molnár D, Török K, Erhardt E, et al.
Effect of caffeine on clozapine pharmacokinetics in healthy volunteers.Randomized controlled trialHumanActiveBritish journal of clinical pharmacology2000
Hägg S, Spigset O, Mjörndal T, et al.
Ibuprofen plus caffeine in the treatment of tension-type headache.Randomized controlled trialHumanActiveClinical pharmacology and therapeutics2000
Diamond S, Balm TK, Freitag FG
Cisplatin, cytarabine, caffeine, and continuously infused 5-fluorouracil (PACE) in the treatment of advanced pancreatic carcinoma: a phase II study.Other primary literatureHumanActiveAmerican journal of clinical oncology2000
Ahmed S, Vaitkevicius VK, Zalupski MM, et al.
[Clinical evaluation of the efficacy of the paracetamol and caffeine combination in the treatment of tension headache].Other primary literatureHumanActiveArquivos de neuro-psiquiatria2000
Rabello GD, Forte LV, Galvão AC
Caffeine citrate for the treatment of apnea of prematurity: a double-blind, placebo-controlled study.Randomized controlled trialHumanActivePharmacotherapy2000
Erenberg A, Leff RD, Haack DG, et al.
Structure-activity relationships for G2 checkpoint inhibition by caffeine analogs.Other primary literatureHumanActiveInternational journal of oncology2000
Jiang X, Lim LY, Daly JW, et al.
[Subcutaneous caffeine poisoning].Other primary literatureHumanActivePresse medicale (Paris, France : 1983)2000
Le Coz J
[Teratogenic and embryotoxic effects of caffeine: facts and hypotheses].ReviewHuman & animalActivePolski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego2000
Burdan F
Treatment of menstruation-associated migraine with the nonprescription combination of acetaminophen, aspirin, and caffeine: results from three randomized, placebo-controlled studies.Randomized controlled trialHumanActiveClinical therapeutics1999
Silberstein SD, Armellino JJ, Hoffman HD, et al.
Effect of caffeine on the vocal folds: a pilot study.Other primary literatureHumanActiveThe Journal of laryngology and otology1999
Akhtar S, Wood G, Rubin JS, et al.
Dietary caffeine as a probe agent for assessment of cytochrome P4501A2 activity in random urine samples.Other primary literatureHumanActiveBritish journal of clinical pharmacology1999
Nordmark A, Lundgren S, Cnattingius S, et al.
Prenatal effects of caffeine and restraint stress in mice.Other primary literatureAnimalActiveProceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)1999
Colomina MT, Sanchez DJ, Esparza JL, et al.
Experimental treatment of the acute cardiovascular toxicity of caffeine.Other primary literatureAnimalActiveJournal of toxicology. Clinical toxicology1999
Strubelt O, Diederich KW
Caffeine-mediated override of checkpoint controls. A requirement for rhp6 (Schizosaccharomyces pombe).Other primary literatureUnknownActiveGenetics1999
Rowley R, Zhang J
Effects of long-term caffeine consumption on renal function in spontaneously hypertensive heart failure prone rats.Other primary literatureAnimalActiveJournal of cardiovascular pharmacology1999
Tofovic SP, Jackson EK
Caffeine increases renal renin secretion in a rat model of genetic heart failure.Other primary literatureAnimalActiveJournal of cardiovascular pharmacology1999
Tofovic SP, Kusaka H, Rominski B, et al.
Is caffeine treatment given to preterm babies a risk factor for SIDS?Other primary literatureHumanActiveArchives of disease in childhood. Fetal and neonatal edition1999
Bock W, Sterniste W, Vallazza U, et al.
Comparative efficacy and safety of calcium carbasalate plus metoclopramide versus ergotamine tartrate plus caffeine in the treatment of acute migraine attacks.Randomized controlled trialHumanActiveEuropean neurology1999
Le Jeunne C, Gómez JP, Pradalier A, et al.
Caffeine intake, tolerance, and withdrawal in women: a population-based twin study.Other primary literatureHumanActiveThe American journal of psychiatry1999
Kendler KS, Prescott CA
Human brain metabolic response to caffeine and the effects of tolerance.Other primary literatureHumanActiveThe American journal of psychiatry1999
Dager SR, Layton ME, Strauss W, et al.
Caffeine overdose in a premature infant: clinical course and pharmacokinetics.Other primary literatureHumanActiveAnaesthesia and intensive care1999
Anderson BJ, Gunn TR, Holford NH, et al.
Severe rhabdomyolysis following massive ingestion of oolong tea: caffeine intoxication with coexisting hyponatremia.Other primary literatureHumanActiveVeterinary and human toxicology1999
Kamijo Y, Soma K, Asari Y, et al.
[Subcutaneous caffeine intoxication].Other primary literatureHumanActivePresse medicale (Paris, France : 1983)1999
Rothmann C, Aussedat M, Noizet M, et al.
Analgesic efficacy of ibuprofen alone and in combination with codeine or caffeine in post-surgical pain: a meta-analysis.Meta-analysisHumanActiveEuropean journal of clinical pharmacology1998
Po AL, Zhang WY
Are adverse drug reactions attributed to fluvoxamine caused by concomitant intake of caffeine?Other primary literatureHumanActiveEuropean journal of clinical pharmacology1998
Spigset O
Acute effects of caffeine ingestion on signal-averaged electrocardiograms.Randomized controlled trialHumanActiveAmerican heart journal1998
Donnerstein RL, Zhu D, Samson R, et al.
Regular caffeine consumption: a balance of adverse and beneficial effects for mood and psychomotor performance.Other primary literatureHumanActivePharmacology, biochemistry, and behavior1998
Rogers PJ, Dernoncourt C
Reinforcing effects of caffeine, ephedrine, and their binary combination in rats.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior1998
Briscoe RJ, Vanecek SA, Vallett M, et al.
Evaluation of the developmental toxicity of caffeine and caffeine metabolites using the frog embryo teratogenesis assay--Xenopus (FETAX).Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association1998
Fort DJ, Stover EL, Propst TL, et al.
Caffeine--an atypical drug of dependence.ReviewHuman & animalActiveDrug and alcohol dependence1998
Daly JW, Fredholm BB
Endorsement of DSM-IV dependence criteria among caffeine users.Other primary literatureHumanActiveDrug and alcohol dependence1998
Hughes JR, Oliveto AH, Liguori A, et al.
Behavioral effects of caffeine and other methylxanthines on children.ReviewHumanActiveExperimental and clinical psychopharmacology1998
Hughes JR, Hale KL
Caffeine based measures of CYP1A2 activity correlate with oral clearance of tacrine in patients with Alzheimer's disease.Randomized controlled trialHumanActiveBritish journal of clinical pharmacology1998
Fontana RJ, deVries TM, Woolf TF, et al.
Caffeine-derived N-nitroso compounds. V. Carcinogenicity of mononitrosocaffeidine and dinitrosocaffeidine in bd-ix rats.Other primary literatureAnimalActiveCarcinogenesis1998
Ivankovic S, Seibel J, Komitowski D, et al.
Mood and psychomotor performance effects of the first, but not of subsequent, cup-of-coffee equivalent doses of caffeine consumed after overnight caffeine abstinence.Randomized controlled trialHumanActiveBehavioural pharmacology1998
Robelin M, Rogers PJ
Caffeine toxicity in a bodybuilder.Other primary literatureHumanActiveJournal of accident & emergency medicine1998
FitzSimmons CR, Kidner N
Caffeine and schizophrenia.ReviewHuman & animalActivePsychiatric services (Washington, D.C.)1998
Hughes JR, McHugh P, Holtzman S
Effects of socioeconomic factors, psychological stress, smoking, alcohol and caffeine on preterm delivery.Other primary literatureUnknownActivePakistan journal of pharmaceutical sciences1998
Obaid-ur-Rahman M, Ahmed T, Rahman S, et al.
Caffeine and Nicotine: Effects on Human Placental Vascular Tone In VitroOther primary literatureUnknownActiveJournal of maternal-fetal investigation : the official journal of French Society of Ultrasound in Medicine and Biology ... [et al.]1998
Ramirez RJ, Kalenic J, Einzig S, et al.
Caffeine-assisted chemotherapy and minimized tumor excision for nonmetastatic osteosarcoma.Other primary literatureHumanActiveAnticancer research1998
Tsuchiya H, Tomita K, Mori Y, et al.
Standards of laboratory practice: theophylline and caffeine monitoring. National Academy of Clinical Biochemistry.ReviewHumanActiveClinical chemistry1998
Pesce AJ, Rashkin M, Kotagal U
Breastfeeding and the use of recreational drugs--alcohol, caffeine, nicotine and marijuana.Other primary literatureHumanActiveBreastfeeding review : professional publication of the Nursing Mothers' Association of Australia1998
Liston J
Quantitative measurement of the effects of caffeine and propranolol on surgeon hand tremor.Randomized controlled trialHumanActiveArchives of ophthalmology (Chicago, Ill. : 1960)1997
Humayun MU, Rader RS, Pieramici DJ, et al.
Enhancement of 131I-mediated cytotoxicity by caffeine.Other primary literatureHuman & animalActiveGynecologic oncology1997
Anderson LL, Lau CC, Gracely EJ, et al.
Myocardial infarction resulting from caffeine overdose in an anorectic woman.Other primary literatureHumanActiveAnnals of emergency medicine1997
Forman J, Aizer A, Young CR
The impact of caffeine use on tobacco cessation and withdrawal.Randomized controlled trialHumanActiveAddictive behaviors1997
Swanson JA, Lee JW, Hopp JW, et al.
Recent advances in caffeine and theobromine toxicities: a review.ReviewHuman & animalActivePlant foods for human nutrition (Dordrecht, Netherlands)1997
Eteng MU, Eyong EU, Akpanyung EO, et al.
Effects of cigarette smoking, caffeine consumption, and alcohol intake on fecundability.Other primary literatureHumanActiveAmerican journal of epidemiology1997
Curtis KM, Savitz DA, Arbuckle TE
Reproductive toxicology. Caffeine.Other primary literatureAnimalActiveEnvironmental health perspectives1997
Human drug discrimination and multiple chemical sensitivity: caffeine exposure as an experimental model.ReviewHumanActiveEnvironmental health perspectives1997
Eissenberg T, Griffiths RR
Reproductive toxicology. Caffeine.Other primary literatureAnimalActiveEnvironmental health perspectives1997
Potentiation of pyridostigmine bromide toxicity in mice by selected adrenergic agents and caffeine.Other primary literatureAnimalActiveVeterinary and human toxicology1997
Chaney LA, Rockhold RW, Mozingo JR, et al.
Acute caffeine ingestion fatalities: management issues.ReviewHumanCorrectedVeterinary and human toxicology1997
Shum S, Seale C, Hathaway D, et al.
Drug- and caffeine-induced headaches.Other primary literatureHumanActiveCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne1997
Shea PE
Behavioral and cognitive effects of methylxanthines. A meta-analysis of theophylline and caffeine.Meta-analysisHumanActiveArchives of pediatrics & adolescent medicine1996
Stein MA, Krasowski M, Leventhal BL, et al.
The caffeine breath test does not identify patients susceptible to tacrine hepatotoxicity.Randomized controlled trialHumanActiveHepatology (Baltimore, Md.)1996
Fontana RJ, Turgeon DK, Woolf TF, et al.
Absence of effect of caffeine on the thyroid in the Syrian golden hamster: results of a 90-day study.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association1996
Bartsch W, Dasenbrock C, Ernst H, et al.
Ibuprofen compared with ibuprofen plus caffeine after third molar surgery.Randomized controlled trialHumanActivePain1996
McQuay HJ, Angell K, Carroll D, et al.
Spectroscopic and molecular modeling studies of caffeine complexes with DNA intercalators.Other primary literatureUnknownActiveBiophysical journal1996
Larsen RW, Jasuja R, Hetzler RK, et al.
Comparative in-vivo genotoxicity of antiviral nucleoside analogues; penciclovir, acyclovir, ganciclovir and the xanthine analogue, caffeine, in the mouse bone marrow micronucleus assay.Other primary literatureAnimalActiveMutation research1996
Haynes P, Lambert TR, Mitchell ID
Unexpected postpartum seizures associated with post-dural puncture headache treated with caffeine.Other primary literatureUnknownActiveInternational journal of obstetric anesthesia1996
Paech M
Inhibition of caffeine metabolism by 5-methoxypsoralen in patients with psoriasis.Other primary literatureHumanActiveBritish journal of clinical pharmacology1996
Bendriss EK, Bechtel Y, Bendriss A, et al.
CYP1A2 activity, gender and smoking, as variables influencing the toxicity of caffeine.Other primary literatureHumanActiveBritish journal of clinical pharmacology1996
Carrillo JA, Benitez J
Cytogenetic effects of caffeine during in vivo mouse oocyte maturation.Other primary literatureAnimalActiveMutagenesis1996
Mailhes JB, Young D, London SN
Saliva as a valid alternative to serum in monitoring intravenous caffeine treatment for apnea of prematurity.Randomized controlled trialHumanActiveTherapeutic drug monitoring1996
Lee TC, Charles BG, Steer PA, et al.
A fluvoxamine-caffeine interaction study.Randomized controlled trialHumanActivePharmacogenetics1996
Jeppesen U, Loft S, Poulsen HE, et al.
Analgesic efficacy of paracetamol and its combination with codeine and caffeine in surgical pain--a meta-analysis.Meta-analysisHumanActiveJournal of clinical pharmacy and therapeutics1996
Zhang WY, Li Wan Po A
Chronic psychiatric patients' use of caffeine: pharmacological effects and mechanisms.ReviewHumanActivePsychological reports1996
Kruger A
Studies on the chronic oral toxicity of an analgesic drug combination consisting of acetylsalicylic acid, paracetamol and caffeine in rats including an electron microscopical evaluation of kidneys.Other primary literatureAnimalActiveArzneimittel-Forschung1996
Lehmann H, Hirsch U, Bauer E, et al.
[Analgesic effect and clinical tolerability of the combination of paracetamol 500 mg and caffeine 50 mg versus paracetamol 400 mg and dextropropoxyphene 30 mg in back pain].Randomized controlled trialHumanActivePresse medicale (Paris, France : 1983)1996
Kuntz D, Brossel R
Overnight caffeine abstinence and negative reinforcement of preference for caffeine-containing drinks.Other primary literatureHumanActivePsychopharmacology1995
Rogers PJ, Richardson NJ, Elliman NA
Caffeine attenuates CNS oxygen toxicity in rats.Other primary literatureAnimalActiveBrain research1995
Bitterman N, Schaal S
Caffeine enhances doxorubicin cardiac toxicity in an animal model.Other primary literatureAnimalActiveJournal of cardiac failure1995
Hosenpud JD, Wright J, Simpson L, et al.
Resolution of caffeine-induced complex dysrhythmia with procainamide therapy.Other primary literatureHumanActiveThe Journal of emergency medicine1995
Chopra A, Morrison L
Occult caffeine as a source of sleep problems in an older population.Other primary literatureHumanActiveJournal of the American Geriatrics Society1995
Brown SL, Salive ME, Pahor M, et al.
Aminophylline versus caffeine citrate for apnea and bradycardia prophylaxis in premature neonates.Other primary literatureHumanActiveActa paediatrica (Oslo, Norway : 1992)1995
Larsen PB, Brendstrup L, Skov L, et al.
Preterm delivery: effects of socioeconomic factors, psychological stress, smoking, alcohol, and caffeine.Other primary literatureHumanActiveBMJ (Clinical research ed.)1995
Peacock JL, Bland JM, Anderson HR
Effect of short duration caffeine treatment on the jejunum of adult albino rats.Other primary literatureUnknownActiveAncient science of life1995
Pushpalatha R, Tulasi KS, Vanithakumari G
Caffeine dependence: fact or fiction?ReviewHumanActiveJournal of the Royal Society of Medicine1995
Strain EC, Griffiths RR
Pharmacokinetics of caffeine in lactating dairy cows.Other primary literatureAnimalActiveAmerican journal of veterinary research1995
DeGraves FJ, Ruffin DC, Duran SH, et al.
[Influence of caffeine on toxicity and pharmacokinetics of paracetamol].Randomized controlled trialHuman & animalActiveAnnales Academiae Medicae Stetinensis1995
Raińska-Giezek T
Cigarette smoking, alcohol consumption, and caffeine intake and fecundability.Other primary literatureHumanActivePreventive medicine1994
Florack EI, Zielhuis GA, Rolland R
Evaluation of the genotoxicity data on caffeine.ReviewHuman & animalActiveRegulatory toxicology and pharmacology : RTP1994
D'Ambrosio SM
Caffeine and nicotine: a review of their joint use and possible interactive effects in tobacco withdrawal.ReviewHumanActiveAddictive behaviors1994
Swanson JA, Lee JW, Hopp JW
Caffeine consumption is associated with decreased severe late toxicity after radiation to the pelvis.Other primary literatureHumanActiveInternational journal of radiation oncology, biology, physics1994
Stelzer KJ, Koh WJ, Kurtz H, et al.
A caffeine- and ryanodine-sensitive intracellular Ca2+ store can act as a Ca2+ source and a Ca2+ sink in PC12 cells.Other primary literatureAnimalActiveThe Biochemical journal1994
Barry VA, Cheek TR
Inhibition of caffeine metabolism by ciprofloxacin in children with cystic fibrosis as measured by the caffeine breath test.Other primary literatureHumanActiveBritish journal of clinical pharmacology1994
Parker AC, Preston T, Heaf D, et al.
Effects of caffeine on intracellular sodium activity in cardiac Purkinje fibres: relation to force.Other primary literatureAnimalActiveBritish journal of pharmacology1994
Iacono G, Vassalle M
Effects of caffeine and related methylxanthines on fetal mouse palates cultured in vitro.Other primary literatureAnimalCorrectedThe Journal of toxicological sciences1994
Kosazuma T, Kawauchi S
Potentiation by caffeine of the frequencies of chromosomal aberrations induced by chronic exposure to fenfluramine in mice.Other primary literatureAnimalActiveDrug and chemical toxicology1994
Sen S, Agarwal K, Mukherjee A, et al.
[Life-threatening caffeine poisoning by using coffee as a psychoactive drug].Other primary literatureHumanActiveWiener klinische Wochenschrift1994
Würl P
Alteration in the tissue retention of [14C]-caffeine in pregnant mice by dimethylsulfoxide.Other primary literatureAnimalActiveNatural toxins1993
Gross SM, Reddy RV, Reddy CS
Developmental toxicity of caffeine in the larvae of Xenopus laevis.Other primary literatureAnimalActiveTeratology1993
Sakamoto MK, Mima S, Kihara T, et al.
Antagonistic effects of caffeine and alcohol on mental performance parameters.Other primary literatureHumanActivePharmacology, biochemistry, and behavior1993
Hasenfratz M, Bunge A, Dal Prá G, et al.
Caffeine potentiates the lethality of tumour necrosis factor in cancer cells.Other primary literatureHuman & animalActiveBritish journal of cancer1993
Belizario JE, Tilly JL, Sherwood SW
Caffeine modulates the antitumor activity and toxic side effects of adriamycin.Other primary literatureAnimalActiveJapanese journal of cancer research : Gann1993
Sadzuka Y, Mochizuki E, Takino Y
Effects of S-2-(3-methylaminopropylamino)ethyl phosphorothioic acid (WR-3689), alone or combined with caffeine, on catecholamine content of mouse hypothalamus.Other primary literatureAnimalActiveProceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)1993
Palazzolo DL, Kumar KS
The acute and chronic effects of ephedrine/caffeine mixtures on energy expenditure and glucose metabolism in humans.Randomized controlled trialHumanActiveInternational journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity1993
Toubro S, Astrup A, Breum L, et al.
Severe caffeine intoxication in a preterm neonate.Other primary literatureHumanActiveEuropean journal of pediatrics1992
van den Anker JN, Jongejan HT, Sauer PJ
Potentiation of cocaine and d-amphetamine toxicity with caffeine.Other primary literatureAnimalActiveThe American journal of emergency medicine1992
Derlet RW, Tseng JC, Albertson TE
A multiple dose comparison of combinations of ibuprofen and codeine and paracetamol, codeine and caffeine after third molar surgery.Randomized controlled trialHumanActiveAnaesthesia1992
McQuay HJ, Carroll D, Guest P, et al.
Caffeine or theophylline for neonatal apnoea?Randomized controlled trialHumanActiveArchives of disease in childhood1992
Scanlon JE, Chin KC, Morgan ME, et al.
Effect of caffeine on maximal strength and power in élite male athletes.Randomized controlled trialHumanActiveBritish journal of sports medicine1992
Jacobson BH, Weber MD, Claypool L, et al.
Caffeine reduces the hepatotoxicity of paracetamol in mice.Other primary literatureAnimalActiveThe Journal of international medical research1992
Raińska T, Juzwiak S, Dutkiewicz T, et al.
Caffeine does not effectively ameliorate, but rather may worsen the ethanol intoxication when assessed by discrete avoidance in mice.Other primary literatureAnimalActiveJapanese journal of pharmacology1992
Kuribara H, Tadokoro S
Low-dose caffeine discrimination and self-reported mood effects in normal volunteers.Other primary literatureHumanActiveJournal of the experimental analysis of behavior1992
Silverman K, Griffiths RR
Wake up and smell the coffee. Caffeine, coffee, and the medical consequences.ReviewHumanActiveThe Western journal of medicine1992
Chou T
Caffeine under examination--a passing grade.Other primary literatureHumanActiveThe Western journal of medicine1992
Myers MG
The addition of intravenous caffeine during an amobarbital interview.Other primary literatureHumanActiveJournal of psychiatry & neuroscience : JPN1992
McCall WV
Smoking and caffeine and alcohol intake during pregnancy in a northern population: effect on fetal growth.Other primary literatureHumanActiveCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne1992
Godel JC, Pabst HF, Hodges PE, et al.
Coronary precautions: should caffeine be restricted in patients after myocardial infarction?ReviewHumanActiveHeart & lung : the journal of critical care1992
Lynn LA, Kissinger JF
Cardiovascular Effects of Caffeine: Misconceptions about caffeine use and caronary heart disease.Other primary literatureUnknownActiveCanadian family physician Medecin de famille canadien1992
Myers MG
Caffeine self-administration, withdrawal, and adverse effects among coffee drinkers.Randomized controlled trialHumanActiveArchives of general psychiatry1991
Hughes JR, Higgins ST, Bickel WK, et al.
Antioxidant behaviour of caffeine: efficient scavenging of hydroxyl radicals.Other primary literatureUnknownActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association1991
Shi X, Dalal NS, Jain AC
Effects of caffeine on tobacco withdrawal.Other primary literatureHumanActiveClinical pharmacology and therapeutics1991
Oliveto AH, Hughes JR, Terry SY, et al.
Lack of interaction between lomefloxacin and caffeine in normal volunteers.Randomized controlled trialHumanActiveAntimicrobial agents and chemotherapy1991
Healy DP, Schoenle JR, Stotka J, et al.
Caffeine clearance by enzyme multiplied immunoassay technique: a simple, inexpensive, and useful indicator of liver function.Other primary literatureHumanActiveGut1991
McDonagh JE, Nathan VV, Bonavia IC, et al.
Effects on birthweight of alcohol and caffeine consumption in smoking women.Other primary literatureHumanActiveJournal of epidemiology and community health1991
Peacock JL, Bland JM, Anderson HR
The effect of caffeine on postprandial blood pressure in the frail elderly.Randomized controlled trialHumanActivePostgraduate medical journal1991
Heseltine D, el-Jabri M, Ahmed F, et al.
Rhabdomyolysis after suicidal ingestion of an overdose of caffeine, acetaminophen and phenazone as a fixed-dose combination (Spalt N).Other primary literatureHumanActiveJournal of toxicology. Clinical toxicology1991
Michaelis HC, Sharifi S, Schoel G
Caffeine modulates the effects of DNA-intercalating drugs in vitro: a flow cytometric and spectrophotometric analysis of caffeine interaction with novantrone, doxorubicin, ellipticine, and the doxorubicin analogue AD198.Other primary literatureAnimalActiveCancer research1991
Traganos F, Kapuscinski J, Darzynkiewicz Z
[Importance of monitoring theophylline and caffeine plasma levels in the management of neonatal apnea].Other primary literatureHumanActiveAnales espanoles de pediatria1991
Soto Alvarez J, Sacristán del Castillo JA
Evaluation of aspirin, caffeine, and their combination in postoperative oral surgery pain.Randomized controlled trialHumanActivePharmacotherapy1990
Forbes JA, Jones KF, Kehm CJ, et al.
Treatment of caffeine toxicity with esmolol.Other primary literatureHumanActiveAnnals of emergency medicine1990
Price KR, Fligner DJ
Dose-dependency of caffeine metabolism with repeated dosing.Randomized controlled trialHumanActiveClinical pharmacology and therapeutics1990
Denaro CP, Brown CR, Wilson M, et al.
Pharmacokinetic evaluation of erythromycin and caffeine administered with bromocriptine.Other primary literatureHumanActiveClinical pharmacology and therapeutics1990
Nelson MV, Berchou RC, Kareti D, et al.
Molecular mechanisms of DNA repair inhibition by caffeine.Other primary literatureUnknownActiveProceedings of the National Academy of Sciences of the United States of America1990
Selby CP, Sancar A
Presentation and management of an acute caffeine overdose.Other primary literatureHumanActivePediatric emergency care1990
Dietrich AM, Mortensen ME
The caffeine breath test and caffeine urinary metabolite ratios in the Michigan cohort exposed to polybrominated biphenyls: a preliminary study.Other primary literatureHumanActiveEnvironmental health perspectives1990
Lambert GH, Schoeller DA, Humphrey HE, et al.
The action of caffeine on X-irradiated HeLa cells. IX. Hypothermic effects.Other primary literatureHumanActiveRadiation research1990
Tolmach LJ, Duncan PG, Beetham KL
Caffeine-Associated Cardiac Dysrhythmia During ECT: Report of Three Cases.Other primary literatureUnknownActiveConvulsive therapy1990
Jaffe R, Brubaker G, Dubin WR, et al.
Phenylpropanolamine and caffeine use among diet center clients.Other primary literatureHumanActiveInternational journal of obesity1990
Lake CR, Rosenberg D, Quirk R
Influence of caffeine administered during pregnancy on the early differentiation of fetal rat ovaries and testes.Other primary literatureAnimalActiveJournal of developmental physiology1990
Pollard I, Williamson S, Magre S
Caffeine-modified electroconvulsive therapy in depressed patients with medical illness.Other primary literatureHumanActiveThe Journal of clinical psychiatry1990
Lurie SN, Coffey CE
Caffeine toxicity is inversely related to DNA repair in simian virus 40-transformed xeroderma pigmentosum cells irradiated with ultraviolet light.Other primary literatureHuman & animalActiveTeratogenesis, carcinogenesis, and mutagenesis1989
Cleaver JE
Transient hypertension after two phenylpropanolamine diet aids and the effects of caffeine: a placebo-controlled follow-up study.Randomized controlled trialHumanActiveThe American journal of medicine1989
Lake CR, Zaloga G, Bray J, et al.
Caffeine and cigarette smoking: behavioral, cardiovascular, and metabolic interactions.Other primary literatureHumanActivePharmacology, biochemistry, and behavior1989
Brown CR, Benowitz NL
Rhabdomyolysis induced by a caffeine overdose.ReviewHumanActiveAnnals of emergency medicine1989
Wrenn KD, Oschner I
Caffeine abstention in the management of anxiety disorders.Other primary literatureHumanActivePsychological medicine1989
Bruce MS, Lader M
Dextromethorphan and caffeine as probes for simultaneous determination of debrisoquin-oxidation and N-acetylation phenotypes in children.Other primary literatureHumanActiveClinical pharmacology and therapeutics1989
Evans WE, Relling MV, Petros WP, et al.
Toxicity of various combinations of X-rays, caffeine, and mercury in mouse embryos.Other primary literatureAnimalActiveInternational journal of radiation biology1989
Müller WU
Cardiotoxic effects of the combined use of caffeine and isoproterenol in the minipig.Other primary literatureAnimalActiveJournal of toxicology and environmental health1989
Vick J, Joseph X, Whitehurst V, et al.
Self-report reliability and symptomatology of habitual caffeine consumption.Other primary literatureHumanActiveBritish journal of clinical pharmacology1989
James JE, Bruce MS, Lader MH, et al.
Interaction between oral ciprofloxacin and caffeine in normal volunteers.Other primary literatureHumanActiveAntimicrobial agents and chemotherapy1989
Healy DP, Polk RE, Kanawati L, et al.
Health and ergogenic effects of caffeine.ReviewHumanActiveBritish journal of sports medicine1989
Jacobson BH, Kulling FA
Fetal arrhythmia caused by excessive intake of caffeine by pregnant women.Other primary literatureHumanActiveBMJ (Clinical research ed.)1989
Oei SG, Vosters RP, van der Hagen NL
Effects on birth weight of smoking, alcohol, caffeine, socioeconomic factors, and psychosocial stress.Other primary literatureHumanActiveBMJ (Clinical research ed.)1989
Brooke OG, Anderson HR, Bland JM, et al.
Reinforcing effects of caffeine in coffee and capsules.Other primary literatureHumanActiveJournal of the experimental analysis of behavior1989
Griffiths RR, Bigelow GE, Liebson IA
Caffeine and babies.Other primary literatureHumanActiveBMJ (Clinical research ed.)1989
Massive caffeine ingestion resulting in death.Other primary literatureHumanActiveVeterinary and human toxicology1989
Mrvos RM, Reilly PE, Dean BS, et al.
Physical dependence on and toxicity from caffeine.Randomized controlled trialHumanActiveNIDA research monograph1989
Hughes JR, Higgins ST, Bickel WK, et al.
[Clinical implications of enhanced caffeine contracture in malignant hyperthermia (MH) and Duchenne muscular dystrophy (DMD)].Other primary literatureHumanActiveRinsho shinkeigaku = Clinical neurology1989
Takagi A, Kojima S, Araki M
[Caffeine plus analgesics-a significant combination.].Other primary literatureUnknownActiveSchmerz (Berlin, Germany)1988
Fox JM
Methylxanthines: toxicity to humans. 2. Caffeine.ReviewHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association1988
Stavric B
Adverse pregnancy outcome in the monkey (Macaca fascicularis) after chronic caffeine exposure.Other primary literatureAnimalActiveThe Journal of pharmacology and experimental therapeutics1988
Gilbert SG, Rice DC, Reuhl KR, et al.
Chronic caffeine or theophylline exposure reduces gamma-aminobutyric acid/benzodiazepine receptor site interactions.Other primary literatureAnimalActiveMolecular pharmacology1988
Roca DJ, Schiller GD, Farb DH
Interindividual and intraindividual variability in acetylation: characterization with caffeine.Other primary literatureHumanActiveClinical pharmacology and therapeutics1988
Hardy BG, Lemieux C, Walker SE, et al.
Caffeine overdose in an adolescent male.Other primary literatureHumanActiveJournal of toxicology. Clinical toxicology1988
Leson CL, McGuigan MA, Bryson SM
Caffeine and its dimethylxanthine metabolites in two cases of caffeine overdose: a cause of falsely elevated theophylline concentrations in serum.Other primary literatureHumanActiveJournal of analytical toxicology1988
Fligner CL, Opheim KE
Birth defects following maternal exposure to ergotamine, beta blockers, and caffeine.Other primary literatureHumanActiveJournal of medical genetics1988
Hughes HE, Goldstein DA
Adverse reaction to use of caffeine in ECT.Other primary literatureHumanActiveThe American journal of psychiatry1988
Acevedo AG, Smith JK
[Caffeine poisoning and a syndrome of salt loss in premature infants].Other primary literatureHumanActiveArchives francaises de pediatrie1988
Zaoui C, Kacet N, Carpentier C, et al.
Interaction of caffeine with acetaminophen in mice: schedule dependency of the antagonism by caffeine of acetaminophen hepatotoxicity and the effects of caffeine metabolites, allopurinol, and diethyl ether.Other primary literatureAnimalActiveResearch communications in chemical pathology and pharmacology1988
Gale GR, Smith AB
The effects of low doses of caffeine on human performance and mood.Other primary literatureHumanActivePsychopharmacology1987
Lieberman HR, Wurtman RJ, Emde GG, et al.
[Toxicity of coffee and caffeine].ReviewHuman & animalActiveDeutsche medizinische Wochenschrift (1946)1987
Strubelt O
The effects of caffeine and aspirin on mood and performance.Randomized controlled trialHumanActiveJournal of clinical psychopharmacology1987
Lieberman HR, Wurtman RJ, Emde GG, et al.
Near-fatal caffeine intoxication treated with peritoneal dialysis.ReviewHumanActivePediatric emergency care1987
Walsh I, Wasserman GS, Mestad P, et al.
Accumulation of caffeine in healthy volunteers treated with furafylline.Other primary literatureHumanActiveBritish journal of clinical pharmacology1987
Tarrus E, Cami J, Roberts DJ, et al.
Treatment of caffeine intoxication by exchange transfusion in a newborn.Other primary literatureHumanActiveActa paediatrica Scandinavica1987
Perrin C, Debruyne D, Lacotte J, et al.
Caffeine and health.ReviewHumanActiveBritish medical journal (Clinical research ed.)1987
Ashton CH
Use of caffeine to lengthen seizures in ECT.Other primary literatureHumanActiveThe American journal of psychiatry1987
Hinkle PE, Coffey CE, Weiner RD, et al.
Facilitation of ECT by caffeine pretreatment.Other primary literatureHumanActiveThe American journal of psychiatry1987
Shapira B, Lerer B, Gilboa D, et al.
Caffeine toxicity: a case of child abuse by drug ingestion.ReviewHumanActiveJournal of forensic sciences1987
Morrow PL
The effects of caffeine on various body systems: a review.ReviewHuman & animalActiveJournal of the American Dietetic Association1987
Leonard TK, Watson RR, Mohs ME
Caffeine as a potential indicator for acetylator status.Other primary literatureHumanActiveJournal of clinical pharmacy and therapeutics1987
Rankin RB, Hudson SA, Fell AF
A tasteless proposal. Caffeine overdose.Other primary literatureHumanActiveNorth Carolina medical journal1987
Mack RB
An animal model for the detection of drug-induced inhibition of caffeine metabolism.Other primary literatureAnimalActiveMethods and findings in experimental and clinical pharmacology1987
Tarrús E, García I, Roberts DJ, et al.
Effect of caffeine on cytotoxicity and sister chromatid exchange induction in sensitive and resistant rat brain tumor cells treated with 1,3-bis(2-chloroethyl)-1-nitrosourea.Other primary literatureAnimalActiveCancer research1987
Aida T, Bodell WJ
Acetaminophen-induced hepatotoxicity: antagonistic action of caffeine in mice.Other primary literatureAnimalActiveResearch communications in chemical pathology and pharmacology1987
Gale GR, Atkins LM, Smith AB, et al.
Analgesic effect of an aspirin-codeine-butalbital-caffeine combination and an acetaminophen-codeine combination in postoperative oral surgery pain.Other primary literatureHumanActivePharmacotherapy1986
Forbes JA, Jones KF, Smith WK, et al.
Potentiation of sulphur mustard or cisplatin-induced toxicity by caffeine in Chinese hamster cells correlates with formation of DNA double-strand breaks during replication on a damaged template.Other primary literatureAnimalActiveMutation research1986
Roberts JJ, Kotsaki-Kovatsi VP
Reproduction study of caffeine administration to male Osborne-Mendel rats.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association1986
Whitby KE, Collins TF, Welsh JJ, et al.
Human coffee drinking: reinforcing and physical dependence producing effects of caffeine.Other primary literatureHumanActiveThe Journal of pharmacology and experimental therapeutics1986
Griffiths RR, Bigelow GE, Liebson IA
Chronic caffeine treatment reduces caffeine but not adenosine effects on cortical acetylcholine release.Other primary literatureAnimalActiveBritish journal of pharmacology1986
Corradetti R, Pedata F, Pepeu G, et al.
Human coffee drinking: manipulation of concentration and caffeine dose.Randomized controlled trialHumanActiveJournal of the experimental analysis of behavior1986
Griffiths RR, Bigelow GE, Liebson IA, et al.
Caffeine: a toxicological overview.ReviewHuman & animalActiveThe Medical journal of Australia1986
Abbott PJ
Acute and chronic toxicity of caffeine: a review.ReviewHuman & animalActiveVeterinary and human toxicology1986
Dalvi RR
Efficacy of low dose combination analgesics: acetaminophen/codeine, aspirin/butalbital/caffeine/codeine, and placebo in oral surgery pain.Other primary literatureHumanActiveAnesthesia progress1986
Desjardins PJ, Cooper SA, Finizio T
Ethnic differences in reactions to drugs and xenobiotics. Caffeine and other drugs.ReviewHumanActiveProgress in clinical and biological research1986
Kalow W
Hyponatremic coma and elevated serum creatine phosphokinase following excessive caffeine intake.Other primary literatureHumanActivePsychiatric journal of the University of Ottawa : Revue de psychiatrie de l'Universite d'Ottawa1986
Kirubakaran V
Enhancement of semustine-induced cytotoxicity by chlorpromazine and caffeine in a human melanoma xenograft.Other primary literatureHuman & animalActiveCancer treatment reports1986
Osieka R, Glatte P, Pannenbäcker R, et al.
Reduction of caffeine teratogenicity in mice by inducing maternal drug metabolism with beta-naphthoflavone.Other primary literatureAnimalActiveTeratology1985
York RG, Randall JL, Scott WJ Jr
Effects of caffeine and chlor-desmethyldiazepam on fighting behavior of mice with different reactivity baselines.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior1985
Traversa U, de Angelis L, Della Loggia R, et al.
The fate of chronically consumed caffeine in the monkey (Macaca fascicularis).Other primary literatureAnimalActiveFundamental and applied toxicology : official journal of the Society of Toxicology1985
Gilbert SG, Stavric B, Klassen RD, et al.
Caffeine distribution in acute toxic response among inbred mice.Other primary literatureAnimalActiveToxicology letters1985
Bonati M, Jiritano L, Bortolotti A, et al.
Caffeine fatality: a case report.Other primary literatureHumanActiveForensic science international1985
Winek CL, Wahba W, Williams K, et al.
Caffeine intoxication: a near fatality.Other primary literatureHumanActiveAnnals of emergency medicine1985
Zimmerman PM, Pulliam J, Schwengels J, et al.
Effects of caffeine, tetracaine, and ryanodine on calcium-dependent oscillations in sheep cardiac Purkinje fibers.Other primary literatureAnimalActiveThe Journal of general physiology1985
Nieman CJ, Eisner DA
Five cases of fatal overdose from caffeine-containing "look-alike" drugs.Other primary literatureHumanActiveJournal of analytical toxicology1985
Garriott JC, Simmons LM, Poklis A, et al.
The effect of caffeine on cardiac rate, rhythm, and ventricular repolarization. Analysis of 18 normal subjects and 18 patients with primary ventricular dysrhythmia.Other primary literatureHumanActiveChest1985
Sutherland DJ, McPherson DD, Renton KW, et al.
Caffeine and human reproduction.ReviewHumanActiveReviews on environmental health1985
James JE, Paull I
[Therapeutic concentrations of theophylline and caffeine during treatment of apnea in premature infants with theophylline].Other primary literatureHumanActiveArchives francaises de pediatrie1985
Alix D, Berthou F, Riche C, et al.
Interstrain variation in acute toxic response to caffeine among inbred mice.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior1984
Seale TW, Johnson P, Carney JM, et al.
The toxicology of chemical interactions during pregnancy in the mouse: caffeine and phenytoin.Other primary literatureAnimalActiveToxicology1984
Skalko RG, Poche PD, Kwasigroch TE
Caffeine toxicity as a cause of acute psychosis in anorexia nervosa.Other primary literatureHumanActiveThe Journal of pediatrics1984
Shaul PW, Farrell MK, Maloney MJ
Caffeine and its dimethylxanthines and fetal cerebral development in rat.Other primary literatureAnimalActiveBrain & development1984
Tanaka H, Nakazawa K, Arima M, et al.
A simple test for acetylator phenotype using caffeine.Other primary literatureHumanActiveBritish journal of clinical pharmacology1984
Grant DM, Tang BK, Kalow W
A double-blind randomized study of an aspirin/caffeine combination versus acetaminophen/aspirin combination versus acetaminophen versus placebo in patients with moderate to severe post-partum pain.Randomized controlled trialHumanActiveThe Journal of international medical research1984
Rubin A, Winter L Jr
Unsuspected caffeine toxicity complicating theophylline therapy.Other primary literatureHumanActiveHuman toxicology1984
Iversen SA, Murphy PG, Leakey TE, et al.
Caffeine and health: Current statusOther primary literatureUnknownUnknownNutrition update / edited by Jean Weininger [and] George M. Briggs1984
Nightingale SL, Flamm WG
[Caffeine poisoning in infants resulting from confusion between dosage forms. Apropos of 5 cases].Other primary literatureHumanActiveTherapie1984
Dubray C, Paire M, Vanlieferinghen P, et al.
Caffeine and its metabolites in caffeine overdose cause falsely elevated serum theophylline measurements.Other primary literatureHumanActiveVeterinary and human toxicology1984
Fligner CL, Opheim KE, Ainardi V
Effects of caffeine in the treatment of apnea.Other primary literatureHuman & animalActiveCanadian Medical Association journal1984
Mullner JW
Maternal cardiovascular response to caffeine infusion in the pregnant ewe.Other primary literatureAnimalActiveAmerican journal of obstetrics and gynecology1983
Conover WB, Key TC, Resnik R
Pre- and postnatal effects of caffeine on brain biogenic amines, cyclic nucleotides and behavior in developing rats.Other primary literatureAnimalActiveThe Journal of pharmacology and experimental therapeutics1983
Concannon JT, Braughler JM, Schechter MD
Adverse effect of maternal caffeine ingestion on fetal cerebrum in rat.Other primary literatureAnimalActiveBrain & development1983
Tanaka H, Nakazawa K, Arima M
Caffeine induces a transient inward current in cultured cardiac cells.Other primary literatureAnimalActiveNature1983
Clusin WT
Caffeine and healthOther primary literatureUnknownUnknownNutrition & the M.D1983
Effects of caffeine being studied for treatment of apnea in newborns.Other primary literatureHumanActiveCanadian Medical Association journal1983
Labow R
The effect of pregnancy on the pharmacokinetics of caffeine.Other primary literatureHumanActiveArchives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement1982
Knutti R, Rothweiler H, Schlatter C
Pharmacokinetic aspects of caffeine in premature infants with apnoea.Other primary literatureHumanActiveEuropean journal of clinical pharmacology1982
Gorodischer R, Karplus M
The effect of caffeine on the cytotoxicity of misonidazole and some other nitroheterocyclic compounds.Other primary literatureAnimalActiveChemico-biological interactions1982
Horsman MR, Stratford IJ
Mechanism by which caffeine potentiates lethality of nitrogen mustard.Other primary literatureAnimalActiveProceedings of the National Academy of Sciences of the United States of America1982
Lau CC, Pardee AB
Reduction in caffeine toxicity by acetaminophen.Other primary literatureHuman & animalActiveJournal of toxicology. Clinical toxicology1982
Deng JF, Spyker DA, Rall TW, et al.
Caffeine: Overview and anthologyOther primary literatureUnknownUnknownNutrition and behavior / Sanford A. Miller1982
Gilbert RM
Delayed elimination of caffeine by women in the last 2 weeks of pregnancy.Other primary literatureHumanActiveCanadian Medical Association journal1982
Parsons WD, Pelletier JG
Investigation of the tumorigenic response to benzo(a)pyrene in aqueous caffeine solution applied orally to Sprague-Dawley rats.Other primary literatureAnimalActiveJournal of cancer research and clinical oncology1981
Brune H, Deutsch-Wenzel RP, Habs M, et al.
Adverse effects of caffeine.Other primary literatureHumanActiveIrish journal of medical science1981
Darragh A, Kenny M, Lambe RF, et al.
Caffeine toxicity secondary to street drug ingestion.Other primary literatureHumanActiveAnnals of emergency medicine1981
May DC, Long T, Madden R, et al.
Mice, men, mustard and methylated xanthines: the potential role of caffeine and related drugs in the sensitization of human tumours to alkylating agents.Other primary literatureHuman & animalActiveBritish journal of cancer1981
Byfield JE, Murnane J, Ward JF, et al.
Decreased systemic clearance of caffeine due to cimetidine.Randomized controlled trialHumanActiveBritish journal of clinical pharmacology1981
Broughton LJ, Rogers HJ
Adverse effects of caffeine and theophylline in the newborn infant.Other primary literatureHumanActiveSeminars in perinatology1981
Howell J, Clozel M, Aranda JV
Acute caffeine overdose in the neonate.Other primary literatureHumanActiveAmerican journal of diseases of children (1960)1980
Banner W Jr, Czajka PA
Sister-chromatid exchanges and chromosomal aberrations in rats treated with phenacetin, phenazone and caffeine.Other primary literatureAnimalActiveMutation research1980
Granberg-Ohman I, Johansson S, Hjerpe A
Use of salivary concentrations in the prediction of serum caffeine and theophylline concentrations in premature infants.Other primary literatureHumanActiveThe Journal of pediatrics1980
Khanna NN, Bada HS, Somani SM
Effects of maternal alcohol, nicotine, and caffeine use during pregnancy on infant mental and motor development at eight months.Other primary literatureHumanActiveAlcoholism, clinical and experimental research1980
Streissguth AP, Barr HM, Martin DC, et al.
Caffeine resistance of Saccharomyces cerevisiae.Other primary literatureUnknownActiveJournal of bacteriology1980
Bard M, Neuhauser JL, Lees ND
Dimer excision in Escherichia coli in the presence of caffeine.Other primary literatureUnknownActiveJournal of bacteriology1980
Rothman RH
Caffeine poisoning in a 19-year-old female.Other primary literatureHumanActiveJournal of forensic sciences1980
McGee MB
Reproductive toxicity of caffeine in Musca dosmestica.Other primary literatureAnimalActiveJournal of toxicology and environmental health1979
Srinivasan A, Kesavan PC
Caffeine secretion into breast milk.Other primary literatureHumanActiveArchives of disease in childhood1979
Tyrala EE, Dodson WE
Caffeine toxicity in a neonate .Other primary literatureHumanActivePediatrics1979
Kulkarni PB, Dorand RD
Caffeine intake and potential effect on health of a segment of northern Canadian indigenous people.Other primary literatureHumanActiveThe International journal of the addictions1979
Farkas CS
Testicular atrophy and impaired spermatogenesis in rats fed high levels of the methylxanthines caffeine, theobromine, or theophylline.Other primary literatureAnimalActiveJournal of environmental pathology and toxicology1979
Friedman L, Weinberger MA, Farber TM, et al.
[Acute theophylline poisoning in an 18-month-old infant. Evidence of partial methylation into caffeine].Other primary literatureHumanActivePediatrie1979
Hartemann E, Baltassat P, Frédérich A, et al.
Effects of cis-platinum(II) diamminedichloride on survival and the rate of DNA synthesis in synchronously growing Chinese hamster V79-379A cells in the absence and presence of caffeine inhibited post-replication repair; evidence for an inducible repair mechanism.Other primary literatureAnimalActiveChemico-biological interactions1978
Fraval HN, Roberts JJ
Toxicity of caffeine.Other primary literatureHuman & animalActiveThe Journal of pediatrics1978
Mace J
Comparative toxicity of caffeine and aminophylline (theophylline ethylenediamine) in young and adult rats.Other primary literatureAnimalActiveBiology of the neonate1978
Warszawski D, Gorodischer R, Kaplanski J
[Experiment to potentiate the effect of cyclophosphamide combined with tempidon and caffeine in leukemia L1210 and Lewis hepatic carcinoma].Other primary literatureAnimalActiveEksperimentalna meditsina i morfologiia1978
Stoichkov I, Milushev A, Todorov D
Testicular atrophy and impaired spermatogenesis in rats fed high levels of the methylxanthines caffeine, theobromine, or theophylline.Other primary literatureAnimalActiveJournal of environmental pathology and toxicology1978
Weinberger MA, Friedman L, Farber TM, et al.
Inhibition by caffeine of post-replication repair in Chinese hamster cells treated with 7-bromomethylbenz(a)anthracene: enhancement of toxicity, chromosome damage and inhibition of ligation of newly-synthesized DNA.Other primary literatureUnknownActiveChemico-biological interactions1977
Roberts JJ, Friedlos F, Van Den Berg HW, et al.
Caffeine toxicity in drosophila strains having different MMS sensitivities.Other primary literatureAnimalActiveMutation research1977
Nigsch J, Graf U, Würgler FE
[Studies on drug interaction of combined drug. I. Toxicological interaction among isopropylantipyrine, allylisopropylacetylurea, Phenacetin and caffeine on acute toxicity in rats (author's transl)].Other primary literatureAnimalActiveYakugaku zasshi : Journal of the Pharmaceutical Society of Japan1977
Kitagawa H, Iwaki R, Kaizukaya F, et al.
Acute mitochondrial toxicity of caffeine in cultured heart cells.Other primary literatureAnimalActiveDrug and chemical toxicology1977
Acosta D, Anuforo D
Toxicology of caffeine or coffee overdose.Other primary literatureHumanActiveBoletin de la Asociacion Medica de Puerto Rico1977
Kaye S
Caffeine intoxication: a case of paroxysmal atrial tachycardia.Other primary literatureHumanActiveJACEP1976
Josephson GW, Stine RJ
Post-replication repair of DNA in Chinese hamster cells treated with cis platinum (II) diamine dichloride. Enhancement of toxicity and chromosome damage by caffeine.Other primary literatureAnimalActiveMutation research1975
Van Den Berg HW, Roberts JJ
Chromosome damage in the bone marrow of mice treated with the methylating agents methyl methanesulphonate and N-methyl-N-nitrosourea in the presence or absence of caffeine, and its relationship with thymoma induction.Other primary literatureAnimalActiveMutation research1975
Frei JV, Venitt S
Proceedings: Synergism between the anti-tumour agent cis platinum (II) diamminedichloride and caffeine: toxicological and molecular studies.Other primary literatureUnknownActiveBritish journal of cancer1975
van den Berg HW, Roberts JJ
Metabolism of N-methylpurines by a Pseudomonas putida strain isolated by enrichment on caffeine as the sole source of carbon and nitrogen.Other primary literatureUnknownActiveJournal of bacteriology1975
Woolfolk CA
Individual responses to methylphenidate and caffeine in children with minimal brain dysfunction.Other primary literatureHumanActiveCanadian Medical Association journal1975
Garfinkel BD, Webster CD, Sloman L
Effect of caffeine on sleep: EEG study in late middle age people.Other primary literatureUnknownActiveBritish journal of clinical pharmacology1974
Březinová V
Letter: Use of caffeine.Other primary literatureHumanActiveCanadian Medical Association journal1974
Mullner JW
[Animal experimental studies on the chronic toxicity of coffee and caffeine].Other primary literatureAnimalActiveZeitschrift fur Ernahrungswissenschaft1973
Strubelt O, Siegers CP, Breining H, et al.
Adverse effects of prolonged administration of caffeine on rat fetus.Other primary literatureAnimalActiveToxicology and applied pharmacology1972
Fujii T, Nishimura H
Effect of caffeine on DNA synthesis in mammalian cells.Other primary literatureAnimalActiveBiophysical journal1972
Lehmann AR
Effect of environmental temperature on the toxicity of caffeine and dextroamphetamine in mice.Other primary literatureAnimalActiveThe Journal of pharmacology and experimental therapeutics1970
Muller PJ, Vernikos-Danellis J
Stimulation of phiX174 production in mitomycin C-treated Escherichia coli cells by caffeine.Other primary literatureUnknownActiveJournal of virology1968
Steiger H, Sinsheimer RL
The influence of a cachexigenic diet on caffeine toxicity.Other primary literatureAnimalActiveToxicology and applied pharmacology1967
Peters JM, Boyd EM
Caffeine toxicity in starved rats.Other primary literatureAnimalActiveToxicology and applied pharmacology1966
Peters JM
The reversible suppression of stationary phase mutation in Escherichia coli by caffeine.Other primary literatureUnknownActiveGenetics1966
Grigg GW, Stuckey J
EXPERIMENTS ON THE MECHANISM OF ACTION OF CHLOROCRESOL AND CAFFEINE.Other primary literatureAnimalActiveBritish journal of pharmacology and chemotherapy1965
BIGGS DF
[POTENTIATION BY THEOPHYLLINE AND CAFFEINE OF THE CONVULSANT EFFECTS AND TOXICITY OF ISONIAZID].Other primary literatureUnknownActiveAnnales pharmaceutiques francaises1964
BESSON H, DEBAY A
[ON OVERDOSES OF CAFFEINE, ETC].Other primary literatureUnknownActiveSvenska lakartidningen1964
WILLIAM-OLSSON L
[ON THE PRENATAL TOXICITY OF DIPHENYLPYRALINE 8-CHLOROTHEOPHYLLINATE WITH REFERENCE TO EXPERIENCES WITH THALIDOMIDE AND CAFFEINE].Other primary literatureUnknownActiveArzneimittel-Forschung1964
KNOCHE C, KOENIG J
The acute oral toxicity in guinea pigs of acetylsalicylic acid, phenacetin, and caffeine, alone and combined.Other primary literatureHumanActiveToxicology and applied pharmacology1960
BOYD EM
The acute oral toxicity of caffeine.Other primary literatureHumanActiveToxicology and applied pharmacology1959
BOYD EM
The acute oral toxicity of a mixture of acetylsalicylic acid, phenacetin, and caffeine.Other primary literatureHumanActiveToxicology and applied pharmacology1959
BOYD EM
[Relative effects of strychnine and caffeine on experimental diphtherial intoxication].Other primary literatureUnknownActiveSuvremenna meditsina1959
LEFTEROV N, ZOZIKOV V
[Increase in the toxicity of caffeine and in its concentration in the brain induced by meprobamate in Mus musculus. Pharmacological and radiochemical data].Other primary literatureHumanActiveArchives internationales de pharmacodynamie et de therapie1959
INSELVINI M, CASIER H
[Pretreatment with caffeine and its effect on the course of diphtherial intoxication in puppies].Other primary literatureAnimalActiveArkhiv patologii1956
SHUTOVA NT
Toxicity of caffeine, theobromine and theophylline.Other primary literatureHumanActiveActa pharmacologica et toxicologica1953
POE CF, JOHNSON CC
[Comparative studies on the acute toxicity of novocaine hydrochloride, novocaine caffeine and novocaine penicillin].Other primary literatureUnknownActiveArzneimittel-Forschung1951
SOEHRING K, AHRENS A, HARDEBECK K
[Toxicity of beverages containing caffeine].Other primary literatureHumanActiveNederlands tijdschrift voor geneeskunde1950
MOSSEL DA
About a case of acute caffeine poisoning.Other primary literatureHumanActiveMedizinische Klinik1946
KOPF H
Pharmacokinetics of caffeine: A systematic analysis of reported data for application in metabolic phenotyping and liver function testingDesign not determinedUnknownUnknown
Grzegorzewski J, Bartsch F, Köller A, et al.
Caffeine and MDMA (ecstasy) exacerbate ER stress triggered by hyperthermiaDesign not determinedUnknownUnknown
Trychta KA, Harvey BK
Cardiovascular and Locomotor Effects of Binary Mixtures of Common “Bath Salts” Constituents: Studies with Methylone, MDPV, and Caffeine in RatsDesign not determinedUnknownUnknown
Seaman RW, Galindo DG, Stinson BT, et al.
Exploring the Relationship between Caffeine Consumption, Caffeine Metabolism, and Sleep Behaviours: A Mendelian Randomisation StudyDesign not determinedUnknownUnknown
Das NR, Woolf B, Page S, et al.
Brain activity as a candidate biomarker for personalised caffeine treatment in premature neonatesDesign not determinedUnknownUnknown
Usman F, Zandvoort CS, Robinson S, et al.
Nighttime Caffeine Intake Increases Motor ImpulsivityDesign not determinedUnknownUnknown
Saldes EB, Sabandal PR, Han K
Caffeine in Food and Dietary Supplements: Examining Safety: Workshop SummaryReviewUnknownActive
Acute Administration of Caffeine: The Effect on Motor Coordination, Higher Brain Cognitive Functions and the Social Behavior of BLC57 MiceDesign not determinedUnknownUnknown
Almosawi S, Baksh H, Qareeballah A, et al.
Key Findings and Implications of a Recent Systematic Review of the Potential Adverse Effects of Caffeine Consumption in Healthy Adults, Pregnant Women, Adolescents, and ChildrenDesign not determinedUnknownUnknown
Doepker C, Franke K, Myers E, et al.
Process Optimisation of Low-caffeine Coffee Using Steam TreatmentDesign not determinedUnknownUnknown
Anggriawan R, Maksum A, Wijaya F, et al.
The Cardiac Effects of Performance-Enhancing Medications: Caffeine vs. Anabolic SteroidsDesign not determinedUnknownUnknown
Sivalokanathan S, Małek Ł, Malhotra A
Caffeine: A Neuroprotectant and Neurotoxin in Traumatic Brain Injury (TBI)Design not determinedUnknownUnknown
Sharma B, Agriantonis G, Brown R, et al.
Caffeine-Induced Neurobehavioral, Developmental Alterations and Oxidative Stress in Zebrafish: A Review Focused On Anxiety, Memory and SleepDesign not determinedUnknownUnknown
Ionescu C, Lungu P, Rarinca V, et al.
Targeting Cancer Metabolism: Modulation of Metformin Antitumor Effects by Caffeine with Involvement of p53 SignalingDesign not determinedUnknownUnknown
Zeljković V, Bogavac M, Dekić M, et al.
Molecular Insights into the Interaction Between Metformin and Caffeine: Time-Dependent Antagonism and Modulation of p53 Signaling in Cancer CellsDesign not determinedUnknownUnknown
Zeljković V, Bogavac M, Dekić M, et al.
Dose-Response Effect of Oral Caffeine Use on Aerobic Exercise Performance: A Systematic Review and Meta-AnalysisDesign not determinedUnknownUnknown
Martins GL, Aparecido JM, Marquezi ML, et al.
Toxicology of Caffeine Poisoning: Molecular Mechanisms, Toxicokinetic Profiles, and Clinical ImplicationsDesign not determinedUnknownUnknown
Socias A, Blancas R
Effect Of Early Caffeine Therapy On Weight Gain In Very Preterm InfantsDesign not determinedUnknownUnknown
Mani S, Kupferman F, Kim R
A Case-Control Study on Maternal caffeine intake during Pregnancy and Risk of Low Birth Weight in Wolaita zone, Southern EthiopiaDesign not determinedUnknownUnknown
Hussen L, Desu B
Brain Activity during Working Memory Tasks after Daily Caffeine Intake: a randomized double-blind placebo-controlled trialDesign not determinedUnknownUnknown
Lin Y, Weibel J, Landolt H, et al.
Monitoring blood caffeine concentration in preterm infants: a retrospective observational studyDesign not determinedUnknownUnknown
Sugino M, Kuboi T, Noguchi Y, et al.
Variability of caffeine metabolism by CYP1A2 polymorphism in different populationsDesign not determinedUnknownUnknown
Chiarella P, Capone P, Sisto R
High caffeine intake as a risk factor for tooth loss: A Study of the National Health and Nutrition Examination Survey (NHANES) 2017-2020Design not determinedUnknownUnknown
Chen Y, Lin L, Zhang Q
Non-Oliguric Acute Renal Failure Secondary to a Potentially Lethal Dose of Caffeine With Acute Intoxication: A Case ReportDesign not determinedUnknownUnknown
Mitomo A, Ishioka K, Yanai M, et al.
Effects of meloxicam and caffeine co-administration on sow farrowing, colostrum quality and piglet performance in smallholder systemsDesign not determinedUnknownUnknown
Acevedo-Herrera F, Yáñez-Pizaña A, Vazquez-Luna D, et al.
Nicotine and Caffeine Co-Use as a Compensatory Response to Early Antipsychotic-Induced Dysfunction: A Case-Based Mechanistic ReportDesign not determinedUnknownUnknown
Dimitriev A
Effect of the timing of caffeine citrate discontinuation on the recurrence of apnea in very low birth weight infantsDesign not determinedUnknownUnknown
CHANG C, XU C, BAO Y, et al.
Development and validation of an RP-HPLC method for the simultaneous determination of artificial sweeteners, preservatives and caffeine in non-alcoholic beveragesDesign not determinedUnknownUnknown
Velkoska-Markovska L, Andonova S, S MJ
A CASE OF CAFFEINE INTOXICATION RESULTING IN HYPOTHERMIADesign not determinedUnknownUnknown
Ohno T, Katsuki S, Miyamoto K, et al.
The use of caffeine in premature infants with apnea: dosage and preventive applicationDesign not determinedUnknownUnknown
Wang Y, Yang F, Yang Y, et al.
A triple blind, randomized study investigating the stress reducing effects of L-theanine following caffeine intakeDesign not determinedUnknownUnknown
Krutzek D, Paulus F, Heinecke K, et al.
A triple blind, randomized study investigating the stress reducing effects of L-theanine following caffeine intakeDesign not determinedUnknownUnknown
Krutzek D, Paulus F, Heinecke K, et al.
A Nickel N-Heterocyclic Biscarbene Complex Derived from Caffeine Enhances Fluconazole Efficacy against Candida glabrataDesign not determinedUnknownUnknown
Malta-Luís C, Romeo G, Francescato G, et al.
Maternal caffeine consumption and its relationship to adverse pregnancy outcomesDesign not determinedUnknownUnknown
Potdar N
COMPOSITION CONTAINING ACETAMINOPHEN, CAFFEINE AND OPTIONALLY ASPIRIN MIXED WITH ALKALINE AGENT FOR ABSORPTION IMPROVEMENTDesign not determinedUnknownUnknown
LJU RUN, KORBO MAJKL, DESAJ DZHEJTIN, et al.
CAFFEINE ENHANCED COFFEE, RECAFFEINATED COFFEE, AND METHODS FOR THEIR PRODUCTIONDesign not determinedUnknownUnknown
NUFERT Thomas H., FOWKES Steven W.
Acetaminophen/Aspirin/CaffeineDesign not determinedUnknownActive
Altabakhi I, Zito PM
Caffeine ToxicityDesign not determinedUnknownActive
Murray A, Traylor J
Ergotamine/CaffeineDesign not determinedUnknownActive
Ngo M, Patel P