Dephosphorylation of branched-chain α-keto acid dehydrogenase E1α (BCKDHA) promotes branched-chain amino acid catabolism and renders cancer cells resistant to X-rays by mitigating DNA damage.

Biochemical and biophysical research communications2025Bo T, Osaki T, Fujii J

Study designOther primary literature

SubjectHuman

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Study design: Other primary literature
Subject: Human
Publication year: 2025
Source: doi.org
Abstract display: Not reproduced here
Publication status: Active
Status checked: 17 Aug 2026
Collected: 3 Aug 2026
Freshness: Current
Review stage: Automated
Record status: Published

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Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)Amino Acids, Branched-ChainCell Line, TumorCell SurvivalDNA DamageHumansPhosphorylationRadiation ToleranceX-Rays

DOI 10.1016/j.bbrc.2024.151154

PMID 39672007

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