Dynamic <sup>13</sup>C-MRI of Branched-Chain Amino Acid Metabolism Using Hyperpolarized [1-<sup>13</sup>C]2-Ketoisocaproate: A Multiband IDEAL Spiral Approach in Rodents and Pigs.Other primary literatureUnknownActiveMagnetic resonance in medicine2026
Skre IS, Christensen DB, Karlsson M, et al.
Hypertension incidence according to branched-chain amino acid intake in Brazilian adults: a six-year follow-up of the CUME study.Other primary literatureHumanActiveEuropean journal of nutrition2026
da Silva FMO, Pimenta AM, Juvanhol LL, et al.
The L-type amino acid transporter inhibitor, BCH, inhibits myotube BCAA uptake and mitochondrial function without altering myotube insulin sensitivity during insulin resistance in C2C12 myotubes.Other primary literatureAnimalActiveActa diabetologica2026
Travis KB, Ragland KJ, Spry ER, et al.
The BCAA metabolism-related gene BCAT1 promotes the progression of bladder urothelial carcinoma through the PI3K/AKT/mTOR signalling pathway.Other primary literatureHumanActiveFunctional & integrative genomics2026
Xin S, Li G, Zhao L, et al.
Branched-Chain Amino Acid Supplementation and Clinical Outcomes in Liver Cirrhosis: A Propensity Score-Matched Multicenter Retrospective Cohort Study.Other primary literatureHumanActiveDigestive diseases and sciences2026
Aldiabat M, Aljabiri Y, Aleyadeh W, et al.
Impaired BCAA Catabolism Contributes To Acute Lung Injury By Triggering Oxidative Stress and Inflammatory Response Via the MAPK Pathway.Other primary literatureAnimalActiveInflammation2026
Xiong DY, Zhang CY, Yang JT, et al.
Comments on investigating leucine-enriched branched-chain amino acid (BCAA) supplementation in elderly chronic kidney disease (CKD) patients.Other primary literatureHumanActiveInternational urology and nephrology2026
Ramzan H, Saeed I, Naveed H
Nutritional Strategy to Minimize Early Lean Mass Loss after SG: The Role of Low-BCAA Soy Peptide Supplements.Other primary literatureHumanActiveObesity surgery2026
Chen Y, Xu J, Pu Y, et al.
Multi-omics pan-cancer analysis reveals heterogeneous BCAA metabolism and its impact on the tumor immune microenvironment and prognosis.Other primary literatureUnknownActiveDiscover oncology2026
Qian J, Wang F, Zhou L, et al.
BCAA catabolism mediates POU2AF1 propionylation to enhance T-ALL development.Other primary literatureHuman & animalActiveCellular oncology (Dordrecht, Netherlands)2026
Dan S, Xu Y, Xie L, et al.
BCAA Metabolic Dyshomeostasis in Cardiovascular Disease: Pathogenic Mechanisms and Intervention.ReviewHuman & animalActiveAmerican journal of cardiovascular drugs : drugs, devices, and other interventions2026
Yin Y, Li H, Hu Q, et al.
Effects of branched-chain amino acid-rich nutritional supplements combined with resistance training on body composition and body function in older patients with sarcopenia.Meta-analysisHumanActiveArchives of gerontology and geriatrics2026
Li H, Zhang R, Ma Y, et al.
Reprogramming of hepatic BCAA metabolism by fructose exacerbates hepatic steatosis.Other primary literatureAnimalActiveBiochemical and biophysical research communications2026
Zhong M, Luo X, Shi M, et al.
Engineering aminoacyl-tRNA synthetase activity to enhance branched-chain amino acid biosynthesis.ReviewUnknownActiveBiochimie2026
Derunets AS, Yanenko AS
Impaired branched-chain amino acid catabolism serves as a metabolic hallmark and therapeutic target in keloids.Other primary literatureHumanActiveBurns : journal of the International Society for Burn Injuries2026
Zhang B, Li Y, Tan X, et al.
Loss of branched-chain amino acid (BCAA) metabolism mediated by IGF2BP1-LPAL2-YBX1 interaction promotes malignancy in gallbladder cancer.Other primary literatureHuman & animalActiveCancer letters2026
Li X, Liu K, Li L, et al.
Distinct metabolic dependency on BCAA defines cancer stemness and malignancy in human triple-negative breast cancer.Other primary literatureHuman & animalActiveCell reports2026
Matsuura K, Shinonaga R, Yamamoto M, et al.
BCAA metabolism promotes lung cancer tumorigenesis by enhancing cholesterol biosynthesis.Other primary literatureHuman & animalActiveCell reports2026
Ma H, Zhang E, Cai J, et al.
Compartmentalized branched-chain amino acid metabolism orchestrates colorectal cancer dissemination via an UMP-vimentin axis.Other primary literatureHuman & animalActiveCell metabolism2026
Ji F, Huang P, Zhou Q, et al.
Structural basis for the anti-aging effects of hydroxyproline-BCAA dipeptides: An integrated computational and experimental approach.Other primary literatureAnimalActiveFood research international (Ottawa, Ont.)2026
Liu L, Wu R, Gao Z, et al.
Enzymatic modification of pumpkin and groundnut seed proteins for enhanced digestibility: BCAA-enriched peptide profiling and structural-functional characterization.Other primary literatureUnknownActiveFood research international (Ottawa, Ont.)2026
Rani M, Belur Shivappa GK, A JL
Impaired BCAA catabolism in macrophages exacerbates sepsis-induced lung injury by modulating mitochondrial AGE-RAGE and mtDNA release.Other primary literatureUnknownActiveFree radical biology & medicine2026
Hong Y, Xu Y, Luo K, et al.
Aspergillus-Enterobacteriaceae dynamics and branched-chain amino acid metabolism in fermented fish sauce.Other primary literatureUnknownActiveInternational journal of food microbiology2026
Fu B, Xu J, Zhang X, et al.
Integrated single-cell and bulk RNA-seq analysis identifies BCAA metabolism-related prognostic signatures in head and neck squamous cell carcinoma.Other primary literatureHumanActiveImmunobiology2026
Lu D, Liang Y, Mo T, et al.
Impaired Lung BCAA Metabolism Promotes Ferroptosis and Resultant Pulmonary Arterial Hypertension-Associated Hepatopathy.Other primary literatureUnknownActiveJACC. Basic to translational science2026
Blake MJ, Hong J, Brownstein A, et al.
Lauric acid engages an O-GlcNAc-sensitive BCKDH regulatory node to modulate branched-chain amino acid oxidation in skeletal myotubes.Other primary literatureUnknownActiveThe Journal of biological chemistry2026
Sumi K, Shioyama M, Munakata K, et al.
The branched-chain amino acid transporter AAT10.2 of Trypanosoma brucei is regulated by substrate availability.Other primary literatureUnknownActiveThe Journal of biological chemistry2026
Oliveres QF, Haindrich AC, Piller S, et al.
Food-derived chlorogenic acid prevents aortic aneurysm and dissection by nutritional restore branched-chain amino acid dyshomeostasis.Other primary literatureHuman & animalActiveThe Journal of nutritional biochemistry2026
Ma ZX, Yin ZQ, Feng ZA, et al.
BCAA catabolism in TRH neurons of paraventricular nucleus regulates energy expenditure.Other primary literatureAnimalActiveMetabolism: clinical and experimental2026
Ming X, Tan J, Yuan M, et al.
Maternal BCAA overnutrition programs persistent dysglycemia in lean adult offspring.Other primary literatureAnimalActiveMolecular metabolism2026
Tzeng J, Ferrer I, Lorenzo DN
Enteral branched-chain amino acid delivery and weaning outcomes in critically ill patients with hypoalbuminemia: a cohort study.Other primary literatureUnknownActiveNutrition (Burbank, Los Angeles County, Calif.)2026
Sun J, Gong X, Zheng J, et al.
Quercetin targets BCAT1 to potentiate CD8<sup>+</sup> T cell immunity by rewiring branched-chain amino acid metabolism against colorectal cancer metastasis.Other primary literatureHuman & animalActivePhytomedicine : international journal of phytotherapy and phytopharmacology2026
Wang C, Xu Y, Ding P, et al.
Paraburkholderia sp. GD17 alleviates damage under drought stress by inducing abscisic acid to regulate the branched-chain amino acid pathway.Other primary literatureUnknownActivePlant physiology and biochemistry : PPB2026
Zhang X, Zhou Y, Shamsi IH, et al.
Branched chain amino acid sufficiency is necessary for proper luteinizing hormone response and testosterone synthesis.Other primary literatureAnimalActiveReproductive biology2026
Shamailova Y, Farooq SA, Gilmore ME, et al.
Activation of a branched-chain amino acid rheostat restores replication-dependent hematopoietic stem cell fitness.Other primary literatureAnimalActiveCell stem cell2026
Bartram J, Treichel S, Song BA, et al.
Individual Branched-Chain Amino Acid Restriction Alters Body Composition without Affecting Hemoglobin in Rats Fed a Low Protein Diet.Other primary literatureUnknownActiveThe Journal of nutrition2026
Jaafar LS, Sous NS, Shehadi HH, et al.
Branched-chain amino acid transferase 2 (BCAT2) deficiency: A case series and systematic review.Other primary literatureUnknownActiveMolecular genetics and metabolism reports2026
Filipic M, Remec ZI, Torkar AD, et al.
BCAT1-elicited branched-chain amino acid catabolism fosters neutrophil-mediated pan-metastasis in pancreatic cancer.Other primary literatureHuman & animalActiveMolecular therapy : the journal of the American Society of Gene Therapy2026
Xie F, Ren YZ, Jian ZW, et al.
The emerging role of branched-chain amino acid metabolism in obesity.ReviewUnknownActiveInternational journal of obesity (2005)2026
Wang D, Wang X, Yang M
Preoperative gut microbial network alterations and BCAA-Related metabolic disturbance in postoperative delirium after cardiac surgery: a prospective matched multi-omic study.Other primary literatureUnknownActiveTranslational psychiatry2026
Lyu C, Wang Z, Zhao R, et al.
MTFR2 promotes VDAC1 oligomerization to reprogram BCAA metabolism in tumor cells to polarize TAMs in LUAD.Other primary literatureUnknownActiveCell death & disease2026
Ge Y, Yu T, Yu S, et al.
Branched-chain amino acid specialization drove diversification within Calditenuaceae (Caldarchaeia) and enables their cultivation.Other primary literatureUnknownActiveNature communications2026
Lai D, Mosier D, Palmer M, et al.
Dietary intake and BCAA metabolism regulate pulmonary fibrosis through KDM4A-mediated epigenetic remodeling in male mice.Other primary literatureHuman & animalActiveNature communications2026
Yao J, Fang S, Lei M, et al.
Inter-organ metabolic feedback via BCAA catabolism regulates glucagon-like hormone secretion in Drosophila.Other primary literatureAnimalActiveNature communications2026
Nishimura T, Arakawa C, Yoshinari Y
Gut microbiota-derived L-theanine promotes host branched-chain amino acid catabolism.Other primary literatureAnimalActiveNature microbiology2026
Wang Y, Liu B, Han Z, et al.
Potential subtype-specific alterations in gut microbiota and branched-chain amino acid metabolism in hydrogen- and methane-predominant small intestinal bacterial overgrowth.Other primary literatureHumanActiveScientific reports2026
Wang Z, Tan W, Zhang P, et al.
Branched-chain amino acid catabolism is potentially deficient in pancreatic cancer with high-neural invasion.Other primary literatureHuman & animalActiveScientific reports2026
Michida H, Hagiwara A, Saito Y, et al.
Theaflavins ameliorate obesity through enhanced antioxidant capacity, a suppressed hepatic BCAA degradation pathway, and gut microbiota modulation.Other primary literatureAnimalActiveFood & function2026
Pan R, Wu P, Zhang Y, et al.
Impact of impaired branched-chain amino acid metabolism on kidney disease.ReviewHuman & animalActiveClinical science (London, England : 1979)2026
Kitada M, Sugahara S, Yasuda-Yamahara M, et al.
Branched-chain amino acid supplementation and endurance performance: reporting guidelines and systematic review of biochemical vs clinical evidence.Systematic reviewHumanActiveThe Physician and sportsmedicine2026
Del Guerra GC, Ohannesian VA, Semerdjian R, et al.
Efficacy of branched chain amino acid administration on cognitive function: a systematic review.Systematic reviewHumanActiveNutritional neuroscience2026
Majid H, Islam SU, Kohli S, et al.
BCAA metabolic reprogramming identifies BCKDK as a therapeutic target in cancer.ReviewUnknownActiveExpert opinion on therapeutic targets2026
Li Z, Zhou Y, Zhang L, et al.
<i>Akkermansia muciniphila</i>'s <i>nifJ</i> gene enhances colostrum sIgA synthesis by branched-chain amino acid degradation to branched short-chain fatty acids.Other primary literatureAnimalActiveGut microbes2026
Wu D, Li F, Xiong W, et al.
Metabolic flux analysis revealed key roles of ArcB in ADI pathway and IlvC in BCAA biosynthesis during <i>Streptococcus suis</i> anaerobic growth and infection.Other primary literatureAnimalActiveVirulence2026
Tang H, Zhang Q, Yang J, et al.
A wheat MYB transcription factor activates defense by repressing TaSIZ1 in response to branched-chain amino acid accumulation.Other primary literatureUnknownActiveThe Plant cell2026
Puthanvila Surendrababu S, Savva L, Korolev AV, et al.
Gut microbiota-mediated branched-chain amino acid metabolism: A novel mechanism by which Bacteroides uniformis improves type 2 diabetes mellitus.Other primary literatureHuman & animalActiveDiabetes, obesity & metabolism2026
Zhang Y, Cai Y, Li X, et al.
Causal role of genetically predicted impairment of branched-chain amino acid catabolism on insulin secretion and insulin resistance in type 2 diabetes.Meta-analysisHumanActiveDiabetes, obesity & metabolism2026
Zhou X, Lu J, Wang Z, et al.
Mitochondrial β-carbonic anhydrase is a conserved metabolic rheostat for branched-chain amino acid catabolism and metabolic flexibility.Other primary literatureUnknownActiveThe New phytologist2026
Sharma N, Sharkey TD, Brandizzi F
Contrasting effects of glutamate and branched-chain amino acid metabolism on acid tolerance in a <i>Castellaniella</i> isolate from acidic groundwater.Other primary literatureUnknownActiveApplied and environmental microbiology2026
Goff JL, Durrence KL, Thorgersen MP, et al.
Differential branched-chain amino acid metabolism in tissues of tumor-bearing male mice.Other primary literatureAnimalActiveAmerican journal of physiology. Regulatory, integrative and comparative physiology2026
Zerrouk M, Delfinis LJ, Perry CGR, et al.
Branched Chain Amino Acid Metabolism in Developmental Brain Injury: Putative Mechanisms and Therapeutic Potential.ReviewHuman & animalActiveDevelopmental neuroscience2026
Cassidy MM, Yudkoff M, Ahrens-Nicklas RC, et al.
GRSF1 Protects Against Heart Failure by Maintaining BCAA Homeostasis.Other primary literatureHuman & animalActiveCirculation2026
Wang H, Wang J, Zhu M, et al.
Branched chain amino acid transaminase 1-mediated pathway promotes proline-dependent collagen production in cardiac myofibroblasts.Other primary literatureUnknownActiveThe Journal of clinical investigation2026
Takizawa N, Hironaka T, Watanabe H, et al.
Branched chain amino acid metabolism and microbiome in adolescents with obesity during weight loss therapy.Other primary literatureHuman & animalActiveThe Journal of clinical investigation2026
McCann JR, Yang C, Bihlmeyer NA, et al.
Exercise suppresses IP6K3 to modulate BCAA metabolism and ferroptosis in MASLD.Other primary literatureUnknownActiveCellular & molecular biology letters2026
Li ZC, Xu FF, Zhao Y, et al.
ZNF33A activates Wnt/β-catenin signaling and promotes BCAA catabolism in colorectal cancer.Other primary literatureHuman & animalActiveCell communication and signaling : CCS2026
Yu W, Chen J, Pu X, et al.
Defective branched-chain amino acid catabolism promotes pulmonary fibrosis by inducing apoptosis resistance of myofibroblasts in mice.Other primary literatureAnimalActiveCell communication and signaling : CCS2026
Xiong DY, Zhang CY, Zhang YF, et al.
Branched-chain amino acid supplementation as a potential trigger for migraine without aura: a case report.Other primary literatureUnknownActiveJournal of medical case reports2026
Saricicek MS, Saricicek AT
Isoleucine and valine regulate the BCAA antagonism by influencing insulin function in broiler chickens.Other primary literatureUnknownActiveJournal of animal science and biotechnology2026
Wang B, Zhang X, Li G, et al.
Plasma Branched-Chain Amino Acid and Cardiovascular Disease Risk Factors: A Longitudinal Analysis of a Lifestyle Trial.Other primary literatureHumanActiveThe Journal of clinical endocrinology and metabolism2026
Hajmir MM, Sayoldin B, Rahnavard A, et al.
Sex differences in cachexia outcomes and branched-chain amino acid metabolism following chemotherapy in aged mice.Other primary literatureAnimalActivePloS one2026
Mora S, Mann G, Adegoke OAJ
The ability of branched-chain amino acid-to-tyrosine ratio (BTR) to assess preoperative liver function of patients with hepatocellular carcinoma.Other primary literatureHumanActivePloS one2026
Takagi A, Fujita A, Tokuda S, et al.
Effect of Branched-Chain Amino Acid Supplementation Alone or Combined With Tryptophan or Methionine on Appetite Control and Related Health Outcomes in Older Adults: Protocol for a Randomized Controlled Trial.Randomized controlled trialHumanActiveJMIR research protocols2026
Zhang S, Ribeiro R, Raubenheimer D, et al.
Urinary Branched-Chain Amino Acid Excretion and Chronic Kidney Disease Progression in Patients With Type 2 Diabetes.Other primary literatureHumanActiveDiabetes2026
Liu JJ, Liu S, Zheng H, et al.
IDH3A Deficiency Compromises Adaptive Thermogenesis and Exacerbates Obesity-Induced Metabolic Dysfunction via Impaired BCKDHA-Dependent BCAA Catabolism.Other primary literatureHuman & animalActiveDiabetes2026
Lu X, Bai N, Lyu J, et al.
Branched-chain amino acid transaminases as promising targets in tumor therapy.ReviewUnknownActiveFrontiers in cell and developmental biology2026
Zhang W, Shen J, Ding X, et al.
Machine learning-derived AS and AIS scores leverage BCAA metabolism and IL4I1 activity for prognosis and tailored therapy in ccRCC.Other primary literatureUnknownActiveFrontiers in cell and developmental biology2026
Weng KQ, Li X, Chen XB, et al.
Redistribution of branched-chain amino acid intake between active and inactive phases modulates hepatic metabolism in rats.Other primary literatureUnknownActiveFrontiers in nutrition2026
Yu K, Lian M, Li H, et al.
Regional Differences in Cardiac Marker Gene Expression and Branched-Chain Amino Acid Metabolism in the Bovine Heart.Other primary literatureUnknownActiveAnimals : an open access journal from MDPI2026
Takiguchi R, Watanabe K, Doai Y, et al.
Metabolomics-Based Analysis Linking Oxidative Stress-Related Branched-Chain Amino Acid (BCAA) Pathway with Atopic Indices to Childhood Allergies.Other primary literatureUnknownActiveAntioxidants (Basel, Switzerland)2026
Ku JL, Su KW, Chiang MH, et al.
Enhancing Nutritional and Health Benefits of Wheat Bran Through Bifunctional LAB Screening and BCAA-Enriched Fermentation.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2026
Lee BH, Han SO, Hong JS, et al.
Blood Focused-Metabolomics and Transcriptomics Uncover Non-Linear Risk Association of Inadequate Dietary Choline Intake-Linked Metabolic Stress with MASLD Through Amino Acid Biomarkers, <i>BCAA</i> and <i>MTORC 1</i>/<i>AKT1</i>/<i>IRS1</i> Mechanistic Mediators: A Nested Case-Control Study.Other primary literatureHumanActiveInternational journal of molecular sciences2026
Wu CH, Lin ML, Wang CY, et al.
Maternal Protein Restriction and Branched-Chain Amino Acid Supplementation Differentially Affect Maternal Energy Balance and Impair Offspring Growth.Other primary literatureAnimalActiveNutrients2026
Redrovan D, Patra S, Aziz MT, et al.
Dietary Branched-Chain Amino Acid Intake Is Associated with Muscle Mass and Handgrip Strength: Evidence from China-Health and Nutrition Survey 2015-2024.Other primary literatureHumanActiveNutrients2026
Xu Z, Ouyang Y, Su C, et al.
Dose-Dependent Effects of Branched-Chain Amino Acid Supplementation on Skeletal Muscle Morphology and Ultrastructure in Exercise-Trained Mice.Other primary literatureAnimalActiveNutrients2026
Zhou Y, Guo X, He H, et al.
Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review).ReviewHuman & animalActiveInternational journal of molecular medicine2026
Xiao Q, Zeng H, Yang R, et al.
Structural basis for the anti-aging effects of hydroxyproline-BCAA dipeptides: An integrated computational and experimental approachOther primary literatureUnknownUnknownFood Research International.2026
Liu L, Wu R, Gao Z, et al.
Enzymatic modification of pumpkin and groundnut seed proteins for enhanced digestibility: BCAA-enriched peptide profiling and structural-functional characterizationOther primary literatureUnknownUnknownFood Research International.2026
Rani M, Belur Shivappa GK, A. JL
G protein-coupled oestrogen receptor regulates branched-chain amino acid metabolism through c-Jun N-terminal kinase.Other primary literatureHumanActiveFEBS letters2025
Gupta A, Shinde PG, Jorvekar S, et al.
Inhibition of CDH11 Activates cGAS-STING by Stimulating Branched Chain Amino Acid Catabolism and Mitigates Lung Metastasis of Adenoid Cystic Carcinoma.Other primary literatureHuman & animalCorrectedAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025
Li RF, Liu S, Gao Q, et al.
Multimodal Metabolomics Analysis Reveals That Classic Decoction Mitigates Myocardial Ischemia-Induced Damage by Modulating Energy and Branched-Chain Amino Acid Metabolism.Other primary literatureAnimalActiveBiomedical chromatography : BMC2025
Ying Z, Pu J, Hu Y, et al.
Contribution of Brain Intrinsic Branched-Chain Amino Acid Metabolism in a Novel Mouse Model of Maple Syrup Urine Disease.Other primary literatureAnimalActiveJournal of inherited metabolic disease2025
Kuhs AC, Ohl L, Thurston T, et al.
Branched-chain amino acid catabolism initiates volatile synthesis in Gentiana triflora.Other primary literatureUnknownActivePlanta2025
Teshima T, Nemoto K, Shimizu M, et al.
Role of branched chain amino acid metabolism on aging.ReviewHuman & animalActiveBiogerontology2025
Wang Z, Yu S, Du X, et al.
Research advances in branched-chain amino acid metabolism in tumors.ReviewHuman & animalActiveMolecular and cellular biochemistry2025
Li Z, Chen S, Wu X, et al.
Anti-sarcopenic effect of leucine-enriched branched-chain amino acid supplementation among elderly chronic kidney disease patients: a double-blinded randomized controlled trial.Randomized controlled trialHumanActiveInternational urology and nephrology2025
Sunsandee N, Thimachai P, Satirapoj B, et al.
The association of dietary branched-chain amino acid intake with hand grip strength and muscular viscoelastic properties in sedentary young women: a cross-sectional study.Other primary literatureHumanActiveIrish journal of medical science2025
Atan RM, Azim D
Multimodal Therapeutic Strategies Targeting BCAA Metabolism in Diabetic Cardiomyopathy: A Path to Cardioprotection.ReviewHuman & animalActiveCardiovascular toxicology2025
Chetana S, Kalyani B
Repurposing branched chain amino acid aminotransferase in the chemoenzymatic synthesis of azacyclic noncanonical amino acids.Other primary literatureUnknownActiveMethods in enzymology2025
Chao TH, Renata H
Impact of comprehensive lifestyle interventions on plasma branched-chain amino acid concentrations: a randomized trial.Randomized controlled trialHumanActiveThe American journal of clinical nutrition2025
Lim YJ, van Dam RM
Facilitation of mucosal healing by estrogen receptor <i>β</i> in ulcerative colitis through suppression of branched-chain amino acid transport and subsequent triggering of autophagy in colonic epithelial cells.Other primary literatureUnknownActiveActa pharmaceutica Sinica. B2025
Guo Y, Zhu Y, Zhang J, et al.
Donepezil treatment mitigates cholinergic system alterations, oxidative stress, neuroinflammation and memory impairment induced by branched-chain amino acid administration in rats.Other primary literatureAnimalActiveBehavioural brain research2025
Lemos IDS, Alano CG, Canarim RO, et al.
Dephosphorylation of branched-chain α-keto acid dehydrogenase E1α (BCKDHA) promotes branched-chain amino acid catabolism and renders cancer cells resistant to X-rays by mitigating DNA damage.Other primary literatureHumanActiveBiochemical and biophysical research communications2025
Bo T, Osaki T, Fujii J
BCAA exaggerated acute and chronic ischemic heart disease through promotion of NLRP3 via Sirt1.Other primary literatureAnimalActiveBiochemical pharmacology2025
Peng Y, Duan Y, Wang D, et al.
PTGFRN promotes non-small cell lung cancer malignant progression and reprograms BCAA metabolism by activating STAT3/BCAT1 pathway.Other primary literatureHuman & animalActiveBiochemical pharmacology2025
Liu F, Li M, Yu P, et al.
Combined network pharmacology and metabolomics reveal that Rubia cordifolia L. ameliorates exhaustive exercise-induced myocardial injury in rats via the BCAA degradation pathway.Other primary literatureAnimalActiveFitoterapia2025
Niu X, Deng J, Zhao Y, et al.
Epigenetic regulation of intracellular branched-chain amino acid homeostasis maintains a normal lifespan.Other primary literatureUnknownActiveiScience2025
Park S, Liu Y, Lim S, et al.
Small-molecule targeting BCAT1-mediated BCAA metabolism inhibits the activation of SHOC2-RAS-ERK to induce apoptosis of Triple-negative breast cancer cells.Other primary literatureHuman & animalActiveJournal of advanced research2025
Huang L, Li G, Zhang Y, et al.
Mechanism of metabolites distribution between 2,3-butanediol and branched-chain amino acid synthesis pathways in Klebsiella pneumoniae.Other primary literatureUnknownActiveJournal of biotechnology2025
Cai Y, Jiang W, Wang Q, et al.
Branched-Chain Amino Acid Supplements for Sarcopenia in Liver Cirrhosis: A Systematic Review and Meta-analysis.ReviewUnknownActiveJournal of clinical and experimental hepatology2025
Abuelazm M, Fares A, Elhady MM, et al.
Integration of UHPLC-MS and mass spectrometry imaging techniques revealed the protective mechanism of Gushudan in postmenopausal osteoporosis rats via branched-chain amino acid metabolism based on the 'kidney-bone' axis.Other primary literatureAnimalActiveJournal of chromatography. B, Analytical technologies in the biomedical and life sciences2025
Ren M, Wang Y, Yuan Y, et al.
Restoration of branched chain amino acid catabolism improves kidney function in preclinical cardiovascular-kidney-metabolic syndrome models.Other primary literatureHuman & animalActiveKidney international2025
Bollinger E, Williams G, Piper ME, et al.
Disruption of branched-chain amino acid homeostasis promotes the progression of DKD via enhancing inflammation and fibrosis-associated epithelial-mesenchymal transition.Other primary literatureHuman & animalActiveMetabolism: clinical and experimental2025
Deng X, Tang C, Fang T, et al.
Gut microbiota-driven BCAA biosynthesis via Staphylococcus aureus -expressed acetolactate synthase impairs glycemic control in type 2 diabetes in South China.Other primary literatureHuman & animalCorrectedMicrobiological research2025
Liang T, Jiang T, Liang Z, et al.
Reversal of BCAA-driven inflammatory senescence by traditional herbal oil prevents atopic dermatitis relapse.Randomized controlled trialHuman & animalActivePhytomedicine : international journal of phytotherapy and phytopharmacology2025
Wang Y, Wang P, Yuan S, et al.
Irf4 participates in benzene-induced hematopoietic senescence through mitochondrial ROS-dependent BCAA catabolism.Other primary literatureAnimalActiveToxicology2025
Liu Z, Wang J, Zhang W, et al.
Protocol for systematic screening of histone H3/H4 mutants to identify histone residues critical for BCAA-dependent replicative lifespan.Other primary literatureUnknownActiveSTAR protocols2025
Park S, Liu Y, Ahn SH
Enzymatic synthesis of 3-hydroxyacyl-CoAs of branched-chain amino acid catabolism.Other primary literatureHuman & animalActiveMolecular genetics and metabolism2025
Wang S, Gilbert K, Yang H, et al.
Single centre retrospective review of plasma branched-chain amino acid levels in children with urea cycle disorders: Impact of treatment modalities and disease severity.Other primary literatureUnknownActiveMolecular genetics and metabolism reports2025
Yeo M, Rehsi P, Yeo JM, et al.
Branched-chain amino acid transferase type 2 (BCAT2) deficiency: Report of an eighth case and literature review.Other primary literatureUnknownActiveMolecular genetics and metabolism reports2025
Mondésert E, Bouchereau J, Schiff M, et al.
<i>Poria cocos</i> Polysaccharide Delays Aging by Enhancing the Antioxidant Ability and Suppressing the Expression of the Branched-Chain Amino Acid Transferase-Encoding Gene in <i>Drosophila melanogaster</i>.Other primary literatureAnimalActiveJournal of agricultural and food chemistry2025
Zhu K, Du D, Shi Y, et al.
<i>Pseudomonas</i> from Potato Inhibited the Pathogenicity of <i>Verticillium nonalfalfae</i> through the BCAA Biosynthesis Pathway.Other primary literatureUnknownActiveJournal of agricultural and food chemistry2025
Wan M, Chen X, Yi X, et al.
PPDPF-mediated regulation of BCAA metabolism enhances mTORC1 activity and drives cholangiocarcinoma progression.Other primary literatureHuman & animalActiveOncogene2025
Li Z, Guan Y, Gao J, et al.
SIRT7 regulates T-cell antitumor immunity through modulation BCAA and fatty acid metabolism.Other primary literatureHuman & animalActiveCell death and differentiation2025
Hu Z, Chen Y, Lei J, et al.
Amino acids and BCAA composition of Mungbean (Vigna radiata L.) seeds and sprouts for plant-based protein applications.Other primary literatureUnknownActiveScientific reports2025
Kim C, Jeon S, Jo YJ, et al.
Dysfunctional BCAA degradation triggers neuronal damage through disrupted AMPK-mitochondrial axis due to enhanced PP2Ac interaction.Other primary literatureAnimalActiveCommunications biology2025
Wu SC, Chen YJ, Su SH, et al.
Haem biosynthesis regulates BCAA catabolism and thermogenesis in brown adipose tissue.Other primary literatureAnimalActiveNature metabolism2025
Duerre DJ, Hansen JK, John SV, et al.
Multi-omic profiling of sarcopenia identifies disrupted branched-chain amino acid catabolism as a causal mechanism and therapeutic target.Other primary literatureHuman & animalActiveNature aging2025
Zuo X, Zhao R, Wu M, et al.
Multi-omics analysis reveals the anti-fatigue mechanism of BCAA-enriched egg white peptides: the role of the gut-muscle axis.Other primary literatureAnimalActiveFood & function2025
Li S, Liu J, Yang Q, et al.
Quantitation of BCAA and BCKA in plasma and patient-centric dried blood microsamples in a clinical setting.Other primary literatureHumanActiveBioanalysis2025
Tierney B, Tuttle PG, Karahanoglu FI, et al.
Glucose-dependent insulinotropic polypeptide/glucagon-like peptide 1 receptor agonist tirzepatide promotes branched chain amino acid catabolism to prevent myocardial infarction in non-diabetic mice.Other primary literatureAnimalActiveCardiovascular research2025
Chen M, Zhao N, Shi W, et al.
The amino acid permease SlAAP6 contributes to tomato growth and salt tolerance by mediating branched-chain amino acid transport.Other primary literatureUnknownActiveHorticulture research2025
Qiang Q, Zhang Z, Li X, et al.
Adjustment of branched-chain amino acid balance fails to prevent feed intake decline in lactating sows fed high soybean meal diets.Other primary literatureAnimalActiveJournal of animal science2025
Humphrey DC, Greiner LL
Association of plasma branched-chain amino acid levels with colorectal cancer risk in a nested case-control study.Other primary literatureHumanActiveJapanese journal of clinical oncology2025
Hisada I, Yamaji T, Sawada N, et al.
Swim Exercise Mitigates BCAA-Induced Atrial Remodeling and AF Susceptibility via Inhibition of Bax-Mediated Mitochondrial Apoptosis.Other primary literatureAnimalActiveFASEB journal : official publication of the Federation of American Societies for Experimental Biology2025
Gong H, Jin L, Zhang Y, et al.
Transcutaneous auricular vagus nerve stimulation promotes adipose tissue browning and mitochondrial integrity by regulating BCAA metabolism in obese rats: an experimental study.Other primary literatureAnimalActiveInternational journal of surgery (London, England)2025
Xin C, Li S, Feng B, et al.
Dietary BCAA supplementation counteracts the beneficial effects of long-term aerobic exercise against obesity and associated metabolic disorders by suppressing FGF21 expression.Other primary literatureHuman & animalActiveDiabetes, obesity & metabolism2025
Zhang J, Zhang X, Li P, et al.
Branched-chain amino acid metabolism: Pathophysiological mechanism and therapeutic intervention in metabolic diseases.ReviewHuman & animalActiveObesity reviews : an official journal of the International Association for the Study of Obesity2025
Mansoori S, Ho MY, Ng KK, et al.
The branched-chain amino acid-related isoleucic acid: recent research advances.ReviewHumanActivePlant biology (Stuttgart, Germany)2025
Mekonnen DW, Ghirardo A, Zhang W, et al.
HDAC7 promotes renal cancer progression by reprogramming branched-chain amino acid metabolism.Other primary literatureHuman & animalActiveScience advances2025
Nam H, Kundu A, Karki S, et al.
Mitochondrial calcium signaling regulates branched-chain amino acid catabolism in fibrolamellar carcinoma.Other primary literatureHumanActiveScience advances2025
Marsh NM, MacEwen MJS, Chea J, et al.
Branched-chain amino acid metabolism supports Roseobacteraceae positive interactions in marine biofilms.Other primary literatureUnknownActiveApplied and environmental microbiology2025
Cui H, Wang S, Fan S, et al.
Activation of branched chain amino acid catabolism protects against nephrotoxic acute kidney injury.Other primary literatureAnimalActiveAmerican journal of physiology. Renal physiology2025
DiMartino S, Revelo MP, Mallipattu SK, et al.
Gut Microbiota-Mediated hsa_circ_0126925 Targets BCAA Metabolic Enzyme BCAT2 to Exacerbate Colorectal Cancer Progression.Other primary literatureHuman & animalActiveMolecular cancer research : MCR2025
Yao H, Xu J, Zhou A, et al.
Branched-Chain Amino Acid Catabolism Promotes Ovarian Cancer Cell Proliferation via Phosphorylation of mTOR.Other primary literatureHuman & animalActiveCancer research communications2025
Lusk HJ, Haughan MA, Bergsten TM, et al.
Lymphatic Endothelial Branched-Chain Amino Acid Catabolic Defects Undermine Cardiac Lymphatic Integrity and Drive HFpEF.Other primary literatureHuman & animalActiveCirculation2025
Guo X, Huang C, Zhang L, et al.
BCAT1 Activation Reprograms Branched-Chain Amino Acid Metabolism and Epigenetically Promotes Inflammation in Diabetic Retinopathy.Other primary literatureAnimalActiveInvestigative ophthalmology & visual science2025
Wang J, Yin Z, Yang J, et al.
Early branched-chain amino acid reduction delays the onset of cognitive decline in a mouse model of Alzheimer's disease.Other primary literatureAnimalActiveJournal of Alzheimer's disease : JAD2025
Mullins CA, Gannaban RB, Kramer A, et al.
Effect of Timing of Branched-Chain Amino Acid Supplementation on Muscle Recovery after Resistance Training in Healthy Males.Randomized controlled trialHumanActiveAmerican journal of men's health2025
Meng K
Effects of branched-chain amino acid- and vitamin D-containing high-protein food supplementation plus exercise on elderly people with decreased physical functions.Other primary literatureHumanActiveBMC geriatrics2025
Nakamura Y, Yokoe T, Ouchi K, et al.
Integrating bioinformatics and machine learning to identify biomarkers of branched chain amino acid related genes in osteoarthritis.Other primary literatureHumanActiveBMC musculoskeletal disorders2025
ZhaYang XZ, Chen YX, Hua WD, et al.
Multiple roles of branched-chain amino acid metabolism in tumour progression.ReviewHuman & animalActiveJournal of biomedical science2025
Wang L, Shi F, Cao Y, et al.
Multi-omics unveils BCAA metabolism markers L-leucine and HMGCS1 as prognostic marker for immunotherapy efficacy in non-small cell lung cancer.Other primary literatureHuman & animalActiveRespiratory research2025
Dai L, Wang X, Lou N, et al.
Impaired cardiac branched-chain amino acid metabolism in a novel model of diabetic cardiomyopathy.Other primary literatureAnimalActiveCardiovascular diabetology2025
Asakura J, Nagao M, Shinohara M, et al.
Branched-chain amino acid and cancer: metabolism, immune microenvironment and therapeutic targets.ReviewHuman & animalActiveJournal of translational medicine2025
Xiong H, Liu R, Xu K, et al.
Cinnamic acid improves insulin sensitivity in prediabetic mice through branched-chain amino acid metabolic reprogramming.Other primary literatureUnknownActiveNutrition & metabolism2025
Wu Y, Qin H, Huang Y, et al.
Acetylation-induced degradation of ECHS1 enhances BCAA accumulation and proliferation in KRAS-mutant colorectal cancer.Other primary literatureHuman & animalActiveJournal of experimental & clinical cancer research : CR2025
Li Z, Liu Z, Lin M, et al.
Codon-specific ribosome stalling reshapes translational dynamics during branched-chain amino acid starvation.Other primary literatureAnimalActiveGenome biology2025
Worpenberg L, Gobet C, Naef F
PRSS55 regulates BCAA metabolism and interacts with BCKDK and BCKDHA in mouse testes and sperm.Other primary literatureUnknownActiveCell & bioscience2025
Ge H, Shen C, Xiong W, et al.
Ningxiang pig-derived lactobacillus reuteri modulates host intramuscular fat deposition via branched-chain amino acid metabolism.Other primary literatureAnimalActiveMicrobiome2025
Yang M, Xie Q, Wang J, et al.
Intravenous branched-chain amino acid administration for the acute treatment of hepatic encephalopathy: a systematic review and meta-analysis.ReviewUnknownActiveJournal of intensive care2025
Yokobori S, Yatabe T, Kondo Y, et al.
Apparent Saturation of Branched-Chain Amino Acid Catabolism After High Dietary Milk Protein Intake in Healthy Adults.Randomized controlled trialHumanActiveThe Journal of clinical endocrinology and metabolism2025
Newton-Tanzer E, Can SN, Demmelmair H, et al.
Role of Branched-Chain Amino Acid Catabolism in the Regulation of Adipocyte Metabolism.ReviewHuman & animalActiveEndocrinology2025
Jiang H, Guo F, Xiao F
Assessment of Risk of Acidosis in Patients with Mild-to-Moderate Chronic Kidney Disease Treated with Intravenous Branched-Chain Amino Acid-Enriched Solution: A Propensity Score Matching Analysis.Other primary literatureHumanActiveBiological & pharmaceutical bulletin2025
Kaji H, Yokooji T, Taogoshi T, et al.
Inactivation of branched-chain amino acid uptake halts Staphylococcus aureus growth and induces bacterial quiescence within macrophages.Other primary literatureHumanCorrectedPLoS pathogens2025
Moldovan A, Flannagan RS, Rühling M, et al.
Comparison of Effectiveness Between Protein and BCAA in Late Evening Snack on Vietnamese Liver Cirrhotic Outpatients: a Randomized Clinical Trial.Randomized controlled trialHumanActiveJournal of gastrointestinal and liver diseases : JGLD2025
Nguyen TT, Nguyen LT, Yamamoto S, et al.
A Review on Branched-Chain Amino Acid Aminotransferase (BCAT) Inhibitors: Current Status, Challenges and Perspectives.ReviewHuman & animalActiveCurrent medicinal chemistry2025
Zhang X, Zhu X, Li Y, et al.
Effect of chronic kidney disease and type 2 diabetes on plasma branched-chain amino acid cross-correlation: a novel metric for evaluating homeostasis.Other primary literatureUnknownActiveJournal of clinical biochemistry and nutrition2025
Ikeda H
Branched-chain amino acid and ketoacid supplementation differentially modulate amino acid and ketoacid metabolisms and profiles in fresh cows.Other primary literatureAnimalActiveJournal of dairy science2025
Sura M, Daddam JR, Gallagher K, et al.
Branched-Chain Amino Acid Metabolic Reprogramming and Cancer: Molecular Mechanisms, Immune Regulation, and Precision Targeting.ReviewHuman & animalActiveOncology research2025
Cai D, Ji J, Yang C, et al.
BCAA metabolism: the Achilles' heel of ovarian cancer, polycystic ovary syndrome, and premature ovarian failure.ReviewHuman & animalActiveFrontiers in endocrinology2025
Zeng T, Liu Y, Tang X, et al.
Sodium-glucose cotransporter 2 inhibitors-but not insulin-enhance renal branched-chain amino acid catabolism.Other primary literatureHuman & animalActiveFrontiers in endocrinology2025
Sakamoto M, Hasuzawa N, Wang L, et al.
BCAA supplementation enhances milk fat synthesis in Yili mares and promotes foal growth through remodeling of intestinal amino acid metabolism.Other primary literatureUnknownActiveFrontiers in microbiology2025
Meng C, Zeng Y, Wang J, et al.
BCAA metabolism in cancer progression and therapy resistance: The balance between fuel and cell signaling.ReviewUnknownActiveFrontiers in pharmacology2025
Zhou Y, Kou J, Li W, et al.
Effects of BCAA supplementation on plasma and mare's milk amino acid contents in <i>Yili</i> mares and growth performance of suckling foals.Other primary literatureUnknownActiveFrontiers in veterinary science2025
Ren X, Xue Y, Shen Z, et al.
Carnitine O-Acetyltransferase as a Central Player in Lipid and Branched-Chain Amino Acid Metabolism, Epigenetics, Cell Plasticity, and Organelle Function.ReviewHuman & animalActiveBiomolecules2025
Volpicella M, Sgobba MN, Laera L, et al.
Branched-Chain Amino Acid Intake and Risk of Incident Type 2 Diabetes: Results from the SUN Cohort.Other primary literatureUnknownActiveBiomedicines2025
de la O V, Bretos-Azcona T, Basterra-Gortari FJ, et al.
BCAA (Branched-Chain Amino Acids) Inhibiting the Autophagy System via the Activation of mTORC1, Thereby Upregulating the Tumor Suppressor PDCD4 in Huh7 Hepatoma Cells.Other primary literatureHumanActiveCells2025
Perveen R, Ozaki I, Takahashi H, et al.
Caprylic Acid Restores Branched-Chain Amino Acid Metabolism in a Mouse Cachexia Model.Other primary literatureUnknownActiveCurrent issues in molecular biology2025
Kawahara I, Fujiwara-Tani R, Mori T, et al.
Impact of Branched-Chain Amino Acid Supplementation on Postoperative Serum Albumin Recovery in Older Adults with Hip Fracture: A Propensity Score-Matched Study.Other primary literatureUnknownActiveJournal of clinical medicine2025
Kang SY, Loh LL, Kim HS, et al.
The Effect of Dexamethasone-Mediated Atrophy on Mitochondrial Function and BCAA Metabolism During Insulin Resistance in C2C12 Myotubes.Other primary literatureUnknownActiveMetabolites2025
Ragland KJ, Travis KB, Spry ER, et al.
Allosteric Conformational Locking of Sestrin2 by Leucine: An Integrated Computational Analysis of Branched-Chain Amino Acid Recognition and Specificity.Other primary literatureHumanActiveMolecules (Basel, Switzerland)2025
Zahid MA, Khan A, Sawali MA, et al.
Obesity Incidence According to Branched-Chain Amino Acid Intake and Plant-Based Diet Index Among Brazilian Adults: A Six-Year Follow-Up of the CUME Study.Other primary literatureHumanActiveNutrients2025
da Silva FMO, Pimenta AM, Juvanhol LL, et al.
Branched-Chain Amino Acid Supplementation Enhances Substrate Metabolism, Exercise Efficiency and Reduces Post-Exercise Fatigue in Active Young Males.Randomized controlled trialHumanActiveNutrients2025
Luan C, Wang Y, Li J, et al.
BrnQ Branched-Chain Amino Acid Transporters Influence Toxin Production by, but Not Growth of, Clostridium perfringens Type A Strain ATCC3624.Other primary literatureUnknownActiveToxins2025
Li J, Mehdizadeh Gohari I, Zhang I, et al.
BCAA catabolism targeted therapy for heart failure with preserved ejection fraction.Other primary literatureHuman & animalActiveTheranostics2025
Wang M, Liu Z, Ren S, et al.
The Effect of Oral Pure Branched-Chain Amino Acid Supplementation on Exercise Performance and Body Composition: A Systematic Review.ReviewUnknownActiveCureus2025
Julea M, Saleh SN
Mechanism of metabolites distribution between 2,3-butanediol and branched-chain amino acid synthesis pathways in Klebsiella pneumoniaeOther primary literatureUnknownUnknownJournal of biotechnology2025
Cai Y, Jiang W, Wang Q, et al.
Branched-chain amino acid-driven metabolic coordination synchronizes lipid and astaxanthin production with biomass valorization in Haematococcus pluvialisOther primary literatureUnknownUnknownIndustrial Crops & Products.2025
Zhang C, Zhang J, Liu W, et al.
Additional isoleucine without valine in an imbalanced branched-chain amino acid diet further exacerbates its negative effects in broilersOther primary literatureUnknownUnknownJournal of Applied Poultry Research.2025
Goo D, Choi J, Lee J, et al.
Branched-Chain Amino Acid Accumulation Fuels the Senescence-Associated Secretory Phenotype.Other primary literatureAnimalActiveAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024
Liang Y, Pan C, Yin T, et al.
Branched-Chain Amino Acids Deficiency Promotes Diabetic Neuropathic Pain Through Upregulating LAT1 and Inhibiting Kv1.2 Channel.Other primary literatureHuman & animalActiveAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024
Zhou ZY, Wang JY, Li ZX, et al.
Adverse plasma branched-chain amino acid profile mirrors fatty muscle degeneration in diabetic heart failure patients.Other primary literatureHumanActiveESC heart failure2024
Kouzu H, Yano T, Katano S, et al.
The BCKDH kinase inhibitor BT2 promotes BCAA disposal and mitochondrial proton leak in both insulin-sensitive and insulin-resistant C2C12 myotubes.Other primary literatureHumanActiveJournal of cellular biochemistry2024
Rivera CN, Smith CE, Draper LV, et al.
Bcat2-Mediated Branched-Chain Amino Acid Catabolism Is Linked to the Aggravated Inflammation in Obese with Psoriasis Mice.Other primary literatureAnimalActiveMolecular nutrition & food research2024
Wang Y, Zhao N, Meng Y, et al.
Differences in branched-chain amino acid to tyrosine ratio (BTR) among etiologies of chronic liver disease progression compared to healthy adults.Other primary literatureHumanActiveJournal of gastroenterology2024
Mino M, Sano A, Kakazu E, et al.
The ilv2 gene, encoding acetolactate synthase for branched chain amino acid biosynthesis, is required for plant pathogenicity by Leptosphaeria maculans.Other primary literatureUnknownActiveMolecular biology reports2024
Chong NF, Van de Wouw AP, Idnurm A
The Association Between Branched-Chain Amino Acid Concentrations and the Risk of Autism Spectrum Disorder in Preschool-Aged Children.Other primary literatureHumanActiveMolecular neurobiology2024
Gao Q, Bi D, Li B, et al.
miR-743b-3p promotes hepatic lipogenesis via branched-chain amino acids (BCAA) metabolism by targeting PPM1K in aged mice.Other primary literatureAnimalActiveArchives of gerontology and geriatrics2024
Lu T, Zheng Y, Chen X, et al.
Deficiency of BCAT2-mediated branched-chain amino acid catabolism promotes colorectal cancer development.Other primary literatureHuman & animalActiveBiochimica et biophysica acta. Molecular basis of disease2024
Kang ZR, Jiang S, Han JX, et al.
Targeted inhibition of branched-chain amino acid metabolism drives apoptosis of glioblastoma by facilitating ubiquitin degradation of Mfn2 and oxidative stress.Other primary literatureHuman & animalActiveBiochimica et biophysica acta. Molecular basis of disease2024
Lu Z, Sun GF, He KY, et al.
CPT1A loss disrupts BCAA metabolism to confer therapeutic vulnerability in TP53-mutated liver cancer.Other primary literatureHuman & animalActiveCancer letters2024
Liu Y, Wang F, Yan G, et al.
Targeting IGF2BP1 alleviated benzene hematotoxicity by reprogramming BCAA metabolism and fatty acid oxidation.Other primary literatureAnimalActiveChemico-biological interactions2024
Wang J, Han L, Liu Z, et al.
BCAA-nitrogen flux in brown fat controls metabolic health independent of thermogenesis.Other primary literatureHuman & animalActiveCell2024
Verkerke ARP, Wang D, Yoshida N, et al.
BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism.Other primary literatureHuman & animalActiveCell host & microbe2024
Ren YM, Zhuang ZY, Xie YH, et al.
Effect of branched-chain amino acid supplementation and exercise on quadriceps muscle quantity and quality in patients with cirrhosis as assessed by ultrasonography: A randomized controlled trial.Randomized controlled trialHumanActiveClinical nutrition ESPEN2024
Sobhy E, Kamal MM, Saad Y, et al.
Study on anti-BmNPV mechanism of branched-chain amino acid aminotransferases in silkworm.Other primary literatureAnimalActiveDevelopmental and comparative immunology2024
Chen C, Chen L, Liu X, et al.
Improvement of branched-chain amino acid production by isolated high-producing protease from Bacillus amyloliquefaciens NY130 on isolated soy/whey proteins and their muscle cell protection.Other primary literatureHuman & animalActiveFood chemistry2024
Jeon SH, Seong HJ, Kim H, et al.
Branched-chain amino acid catabolic defect in vascular smooth muscle cells drives thoracic aortic dissection via mTOR hyperactivation.Other primary literatureHuman & animalActiveFree radical biology & medicine2024
Yu L, Huang T, Zhao J, et al.
The role of brown adipose tissue in branched-chain amino acid clearance in people.Other primary literatureUnknownActiveiScience2024
Abdelhafez YG, Wang G, Li S, et al.
Impaired branched-chain amino acid (BCAA) catabolism during adipocyte differentiation decreases glycolytic flux.Other primary literatureHuman & animalActiveThe Journal of biological chemistry2024
Green CR, Alaeddine LM, Wessendorf-Rodriguez KA, et al.
Plasma metabolic profiling reveals that crude and processed Polygonatum cyrtonema hua extract ameliorates myocardial ischemia-induced damage by regulating branched-chain amino acid and energy metabolism.Other primary literatureAnimalActiveJournal of chromatography. B, Analytical technologies in the biomedical and life sciences2024
Lv W, Yang Y, Lv Y, et al.
Deceased donor kidney function and branched chain amino acid metabolism during ex vivo normothermic perfusion.Other primary literatureHumanActiveKidney international2024
Ahmadi A, Yu J, Loza JE, et al.
Branched-chain amino acid catabolic defect promotes α-cell proliferation via activating mTOR signaling.Other primary literatureAnimalActiveMolecular and cellular endocrinology2024
Yang Y, Wang S, Sheng C, et al.
Fueling the fight against cancer: Exploring the impact of branched-chain amino acid catalyzation on cancer and cancer immune microenvironment.ReviewHuman & animalActiveMetabolism: clinical and experimental2024
Ma Q, Li H, Song Z, et al.
RNA-binding protein YBX3 promotes PPARγ-SLC3A2 mediated BCAA metabolism fueling brown adipogenesis and thermogenesis.Other primary literatureAnimalActiveMolecular metabolism2024
Chen LY, Wang LW, Wen J, et al.
Branched-chain amino acid supplementation drives dynamic changes in gut microbiota without impairing glucose and lipid homeostasis at the different stages of insulin resistance in mice on a high-fat diet.Other primary literatureAnimalActiveNutrition (Burbank, Los Angeles County, Calif.)2024
Liu R, Yang Y, Shi G, et al.
The nitrate transporter-sensor MtNPF6.8 regulates the branched chain amino acid/pantothenate metabolic pathway in barrel medic (Medicago truncatula Gaertn.) root tip.Other primary literatureUnknownActivePlant physiology and biochemistry : PPB2024
Tarkowski ŁP, Clochard T, Blein-Nicolas M, et al.
Different dietary branched-chain amino acid ratios, crude protein levels, and protein sources can affect the growth performance and meat yield in broilers.Other primary literatureAnimalActivePoultry science2024
Goo D, Singh AK, Choi J, et al.
Effects of branched-chain amino acid imbalance and dietary valine and isoleucine supplementation in modified corn-soybean meal diets with corn distillers dried grains with solubles on growth performance, carcass quality, intestinal health, and cecal microbiome in Cobb 500.Other primary literatureAnimalActivePoultry science2024
Goo D, Lee J, Paneru D, et al.
Effects of calorie, protein, and branched chain amino acid restriction on ovarian aging in mice.Other primary literatureAnimalActiveReproductive biology2024
Veiga GB, Zanini BM, Garcia DN, et al.
Interior decorative volatile organic compounds exposure induces sleep disorders through aberrant branched chain amino acid transaminase 2 mediated glutamatergic signaling resulting from a neuroinflammatory cascade.Other primary literatureAnimalActiveThe Science of the total environment2024
Zheng J, Wu M, Pang Y, et al.
Partial suppression of BCAA catabolism as a potential therapy for BCKDK deficiency.Other primary literatureUnknownActiveMolecular genetics and metabolism reports2024
Ohl L, Kuhs A, Pluck R, et al.
BCKDK modification enhances the anticancer efficacy of CAR-T cells by reprogramming branched chain amino acid metabolism.Other primary literatureHuman & animalActiveMolecular therapy : the journal of the American Society of Gene Therapy2024
Yang Q, Yang Q, Zhu X, et al.
Elevated BCAA catabolism reverses the effect of branched-chain ketoacids on glucose transport in mTORC1-dependent manner in L6 myotubes.Other primary literatureAnimalActiveJournal of nutritional science2024
Mann G, Adegoke OAJ
The role of BCAA metabolism in metabolic health and disease.ReviewHuman & animalActiveExperimental & molecular medicine2024
Choi BH, Hyun S, Koo SH
Branched-chain amino acid transaminase 1 confers EGFR-TKI resistance through epigenetic glycolytic activation.Other primary literatureHuman & animalActiveSignal transduction and targeted therapy2024
Zhang T, Pan Z, Gao J, et al.
Increased rumen Prevotella enhances BCAA synthesis, leading to synergistically increased skeletal muscle in myostatin-knockout cattle.Other primary literatureAnimalActiveCommunications biology2024
Hai C, Hao Z, Bu L, et al.
Enhanced branched-chain amino acid metabolism improves age-related reproduction in C. elegans.Other primary literatureAnimalActiveNature metabolism2024
Lesnik C, Kaletsky R, Ashraf JM, et al.
Walking exercise through smartphone application plus branched-chain amino acid supplementation benefits skeletal muscle mass and strength in liver cirrhosis: A prospective control trial.Other primary literatureHumanActiveZeitschrift fur Gastroenterologie2024
Xiang Q, Xiong J, Zhao ZJ, et al.
Genome-wide association studies identifies genetic loci related to fatty acid and branched-chain amino acid metabolism and histone modifications under varying nitrogen treatments in safflower (Carthamus tinctorius).Other primary literatureUnknownActiveFunctional plant biology : FPB2024
Ali F, Arif MAR, Ali A, et al.
BCAA interactions: how do they influence broiler performance, intestinal morphometry, lipid profile, and liver health?Other primary literatureAnimalActiveArchives of animal nutrition2024
Oliveira CH, Dias KMM, Schultz ÉB, et al.
Mitolnc controls cardiac BCAA metabolism and heart hypertrophy by allosteric activation of BCKDH.Other primary literatureHuman & animalActiveNucleic acids research2024
Weiss M, Hettrich S, Hofmann T, et al.
Branched-chain amino acid transaminase 1 regulates glioblastoma cell plasticity and contributes to immunosuppression.Other primary literatureHuman & animalActiveNeuro-oncology2024
Boskovic P, Wilke N, Man KH, et al.
The Soybean Cyst Nematode Effector Cysteine Protease 1 (CPR1) Targets a Mitochondrial Soybean Branched-Chain Amino Acid Aminotransferase (GmBCAT1).Other primary literatureAnimalActiveMolecular plant-microbe interactions : MPMI2024
Margets A, Foster J, Kumar A, et al.
Reduced Branched-Chain Amino Acid Intake Improved High-Fat Diet-Induced Nonalcoholic Fatty Pancreas Disease in Mice.Other primary literatureAnimalActivePancreas2024
Lu J, Pan T, Gao J, et al.
Branched-chain amino acid supplementation does not improve measures of sarcopenia in cirrhosis: results of a randomised controlled trial.Randomized controlled trialHumanActiveAlimentary pharmacology & therapeutics2024
Hey P, Hoermann R, Sinclair M, et al.
Transcription factor EB reprograms branched-chain amino acid metabolism and promotes pancreatic cancer progression via transcriptional regulation of BCAT1.Other primary literatureHuman & animalActiveCell proliferation2024
Wang T, Hu Q, Li B, et al.
Branched-chain amino acid levels are inversely associated with incident and prevalent chronic kidney disease in people with type 2 diabetes.Other primary literatureHumanActiveDiabetes, obesity & metabolism2024
de Klerk JA, Bijkerk R, Beulens JWJ, et al.
Serum branched-chain amino acid levels are associated with fracture risk in Japanese women.Other primary literatureHumanActiveGeriatrics & gerontology international2024
Urano T, Kuroda T, Uenishi K, et al.
Functional characterization of the dbu locus for D-branched-chain amino acid catabolism in Pseudomonas putida.Other primary literatureUnknownActiveApplied and environmental microbiology2024
Fulton RL, Downs DM
Maintenance of the branched-chain amino acid transporter LAT1 counteracts myotube atrophy following chemotherapy.Other primary literatureHumanActiveAmerican journal of physiology. Cell physiology2024
Mora S, Adegoke OAJ
BCAA was more closely associated with visceral fat area than subcutaneous fat area in patients of type 2 diabetes mellitus: a cross-sectional study.Other primary literatureHumanActiveBMC endocrine disorders2024
Cai X, Li W, Wang L, et al.
Early intravenous branched-chain amino acid-enriched nutrition supplementation in older patients undergoing gastric surgery: a randomized clinical trial.Randomized controlled trialHumanActiveNutrition journal2024
Ma Y, Zhao X, Pan Y, et al.
BCAA mediated microbiota-liver-heart crosstalk regulates diabetic cardiomyopathy via FGF21.Other primary literatureAnimalActiveMicrobiome2024
Zheng H, Zhang X, Li C, et al.
BCAA metabolism in pancreatic cancer affects lipid balance by regulating fatty acid import into mitochondria.Other primary literatureUnknownActiveCancer & metabolism2024
Gotvaldová K, Špačková J, Novotný J, et al.
Protein phosphatase 2Cm-regulated branched-chain amino acid catabolic defect in dorsal root ganglion neurons drives pain sensitization.Other primary literatureAnimalActiveActa neuropathologica communications2024
Lian N, Li F, Zhou C, et al.
Attenuating Muscle Damage Biomarkers and Muscle Soreness After an Exercise-Induced Muscle Damage with Branched-Chain Amino Acid (BCAA) Supplementation: A Systematic Review and Meta-analysis with Meta-regression.Systematic reviewUnknownActiveSports medicine - open2024
Salem A, Ben Maaoui K, Jahrami H, et al.
Sex Differences in Branched-chain Amino Acid and Tryptophan Metabolism and Pathogenesis of Youth-onset Type 2 Diabetes.Other primary literatureHumanActiveThe Journal of clinical endocrinology and metabolism2024
Hernandez N, Lokhnygina Y, Ramaker ME, et al.
Association of Elevated Serum Branched-chain Amino Acid Levels With Longitudinal Skeletal Muscle Loss.Other primary literatureUnknownActiveJournal of the Endocrine Society2024
Imai D, Nakanishi N, Shinagawa N, et al.
Sex differences in cachexia and branched-chain amino acid metabolism following chemotherapy in mice.Other primary literatureAnimalActivePhysiological reports2024
Mora S, Mann G, Adegoke OAJ
Disruption of BCAA degradation is a critical characteristic of diabetic cardiomyopathy revealed by integrated transcriptome and metabolome analysis.Other primary literatureUnknownActiveOpen life sciences2024
Wu Y, Jiang W, Wang J, et al.
Integrated single-cell and bulk characterization of branched chain amino acid metabolism-related key gene BCAT1 and association with prognosis and immunogenicity of clear cell renal cell carcinoma.Other primary literatureHumanActiveAging2024
Zheng J, Liu Y, Wang J, et al.
Exploiting branched-chain amino acid metabolism and NOTCH3 expression to predict and target colorectal cancer progression.Other primary literatureHuman & animalActiveFrontiers in immunology2024
Shen K, Zhu C, Wu J, et al.
Branched-chain amino acid catabolism promotes M2 macrophage polarization.Other primary literatureAnimalActiveFrontiers in immunology2024
Lu M, Luo D, Zhang Z, et al.
Branched-chain amino acid supplementation and voluntary running have distinct effects on the serum metabolome of rats with high or low intrinsic aerobic capacity.Other primary literatureUnknownActiveFrontiers in nutrition2024
Karvinen S, Korhonen TK, Kiviö R, et al.
Association between branched-chain amino acid levels and gastric cancer risk: large-scale prospective cohort study.Other primary literatureUnknownActiveFrontiers in nutrition2024
Yu L, Bao S, Zhu F, et al.
Branched-Chain Amino Acid (BCAA) Oligopeptide Determination from Whey Proteins: Preparation, Peptide Profiles, and Anti-Fatigue Activity.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2024
Zhu Q, Zhou R, Zhu X, et al.
Oligonol®, an Oligomerized Polyphenol from Litchi chinensis, Enhances Branched-Chain Amino Acid Transportation and Catabolism to Alleviate Sarcopenia.Other primary literatureAnimalActiveInternational journal of molecular sciences2024
Chang YC, Chen YC, Chan YC, et al.
Fructose Reduces Mitochondrial Metabolism and Increases Extracellular BCAA during Insulin Resistance in C2C12 Myotubes.Other primary literatureAnimalActiveNutrients2024
Cook NE, McGovern MR, Zaman T, et al.
Branched-Chain Amino Acid Degradation Pathway was Inactivated in Colorectal Cancer: Results from a Proteomics Study.Other primary literatureUnknownActiveJournal of Cancer2024
Lian S, Liu S, Wu A, et al.
A review on aroma-active compounds derived from branched-chain amino acid in fermented meat products: Flavor contribution, formation pathways, and enhancement strategiesOther primary literatureUnknownUnknownTrends in Food Science & Technology.2024
Chen L, Liu R, Wu M, et al.
Influence of varying branched-chain amino acid ratio in diets containing corn gluten meal, L-isoleucine, and L-valine on 0–21 d turkey poult performance, relative mTOR activation, and apparent ileal amino acid digestibilityOther primary literatureUnknownUnknownJournal of Applied Poultry Research.2024
Estanich EB, Bowen KM, Knarr LE, et al.
Effect and feasibility of the combination of branched chain amino acid and exercise therapy on muscle mass and echo intensity of muscle in orthopedic patients in a convalescent rehabilitation hospital: A crossover trial.Other primary literatureUnknownActiveHealth science reports2023
Ikeda T, Suzuki S, Aimoto K, et al.
Kidney urinary biomarkers in patients with branched-chain amino acid and cobalamin metabolism defects.Other primary literatureHumanActiveJournal of inherited metabolic disease2023
Köpfer F, Garbade SF, Klingbeil K, et al.
Mulberry leaf water extract alleviates type 2 diabetes in mice via modulating gut microbiota-host co-metabolism of branched-chain amino acid.Other primary literatureAnimalActivePhytotherapy research : PTR2023
Zheng XX, Li DX, Li YT, et al.
Targeting BCAA metabolism to potentiate metformin's therapeutic efficacy in the treatment of diabetes in mice.Other primary literatureHuman & animalActiveDiabetologia2023
Zhao X, Zhang X, Pei J, et al.
Early administration of postoperative BCAA-enriched PPN may improve lean body mass loss in gastric cancer patients undergoing gastrectomy.Randomized controlled trialHumanActiveLangenbeck's archives of surgery2023
Sakuraya M, Yamashita K, Honda M, et al.
Effect of AMPK activation and glucose availability on myotube LAT1 expression and BCAA utilization.Other primary literatureAnimalActiveAmino acids2023
Rivera CN, Watne RM, Brown ZA, et al.
Branched-chain amino acid supplementation does not enhance lean tissue accretion in low birth weight neonatal pigs, despite lower Sestrin2 expression in skeletal muscle.Other primary literatureAnimalActiveAmino acids2023
Yonke JA, Seymour KA, El-Kadi SW
The effect of insulin resistance on extracellular BCAA accumulation and SLC25A44 expression in a myotube model of skeletal muscle insulin resistance.Other primary literatureHumanActiveAmino acids2023
Rivera CN, Watne RM, Wommack AJ, et al.
Branched-Chain Amino Acid Metabolism in the Failing Heart.ReviewHumanActiveCardiovascular drugs and therapy2023
Karwi QG, Lopaschuk GD
Branched-chain amino acids (BCAA) administration increases autophagy and the autophagic pathway in brain tissue of rats submitted to a Maple Syrup Urine Disease (MSUD) protocol.Other primary literatureAnimalActiveMetabolic brain disease2023
Fermo KT, da Silva Lemos I, Farias HR, et al.
Association between type 2 diabetes and branched chain amino acids (BCAA); a case-control study.Other primary literatureUnknownCorrectedJournal of diabetes and metabolic disorders2023
Torki SA, Bahadori E, Aghakhaninejad Z, et al.
Centella asiatica (L.) Urb. Extract ameliorates branched-chain amino acid (BCAA) metabolism in acute reserpine-induced stress zebrafish model via 1H Nuclear Magnetic Resonance (NMR)-based metabolomics approach.Other primary literatureAnimalActiveComparative biochemistry and physiology. Toxicology & pharmacology : CBP2023
Zakaria F, Akhtar MT, Wan Norhamidah WI, et al.
Association of plasma branched-chain amino acid with multiple cancers: A mendelian randomization analysis.Other primary literatureHumanActiveClinical nutrition (Edinburgh, Scotland)2023
Xu H, Wang X, Xu X, et al.
Intravenous BCAA Infusion Does Not Lead to a Sustained Recovery From Overt HE in ACLF - An Open Label Randomized Clinical Trial.Other primary literatureUnknownActiveJournal of clinical and experimental hepatology2023
Mehtani R, Premkumar M, Garg S, et al.
Comparison of an Antioxidant Source and Antioxidant Plus BCAA on Athletic Performance and Post Exercise Recovery of Horses.Other primary literatureAnimalActiveJournal of equine veterinary science2023
Kent E, Coleman S, Bruemmer J, et al.
Insulin resistance promotes extracellular BCAA accumulation without altering LAT1 content, independent of prior BCAA treatment in a myotube model of skeletal muscle.Other primary literatureHumanActiveMolecular and cellular endocrinology2023
Rivera CN, Kamer MM, Rivera ME, et al.
Mitochondrial pyruvate carrier inhibition initiates metabolic crosstalk to stimulate branched chain amino acid catabolism.Randomized controlled trialHuman & animalActiveMolecular metabolism2023
Ferguson D, Eichler SJ, Yiew NKH, et al.
Effect of genetically determined BCAA levels on cardiovascular diseases and their risk factors: A Mendelian randomization study.Other primary literatureHumanActiveNutrition, metabolism, and cardiovascular diseases : NMCD2023
Zuo Z, Tong Y, Li M, et al.
Lower serum branched-chain amino acid catabolic intermediates are predictive signatures specific to patients with diabetic foot.Other primary literatureHumanActiveNutrition research (New York, N.Y.)2023
Wang T, Wang M, Liu L, et al.
The effects of arginine and branched-chain amino acid supplementation to reduced-protein diet on intestinal health, cecal short-chain fatty acid profiles, and immune response in broiler chickens challenged with Eimeria spp.Other primary literatureAnimalActivePoultry science2023
Liu G, Ajao AM, Shanmugasundaram R, et al.
Elevated branched-chain amino acid promotes atherosclerosis progression by enhancing mitochondrial-to-nuclear H2O2-disulfide HMGB1 in macrophages.Other primary literatureHuman & animalActiveRedox biology2023
Zhao S, Zhou L, Wang Q, et al.
METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism.Other primary literatureHuman & animalActiveCell stem cell2023
Han L, Dong L, Leung K, et al.
Loss of BCAA catabolism enhances Rab1A-mTORC1 signaling activity and promotes tumor proliferation in NSCLC.Other primary literatureUnknownActiveTranslational oncology2023
Xue M, Xiao J, Jiang W, et al.
Cell-autonomous effect of cardiomyocyte branched-chain amino acid catabolism in heart failure in mice.Other primary literatureAnimalActiveActa pharmacologica Sinica2023
Yu JY, Cao N, Rau CD, et al.
Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma.Other primary literatureHumanActiveBritish journal of cancer2023
Kitagawa A, Osawa T, Noda M, et al.
PPM1K mediates metabolic disorder of branched-chain amino acid and regulates cerebral ischemia-reperfusion injury by activating ferroptosis in neurons.Other primary literatureAnimalActiveCell death & disease2023
Li T, Zhao L, Li Y, et al.
MicroRNA-mediated attenuation of branched-chain amino acid catabolism promotes ferroptosis in chronic kidney disease.Other primary literatureHuman & animalActiveNature communications2023
Sone H, Lee TJ, Lee BR, et al.
Branched-chain amino acid catabolism in muscle affects systemic BCAA levels but not insulin resistance.Other primary literatureAnimalActiveNature metabolism2023
Blair MC, Neinast MD, Jang C, et al.
Enhanced BCAT1 activity and BCAA metabolism promotes RhoC activity in cancer progression.Other primary literatureHumanActiveNature metabolism2023
Qian L, Li N, Lu XC, et al.
Impaired BCAA catabolism in adipose tissues promotes age-associated metabolic derangement.Other primary literatureAnimalActiveNature aging2023
Han HS, Ahn E, Park ES, et al.
Branched-chain amino acid modulation of lipid metabolism, gluconeogenesis, and inflammation in a finishing pig model: targeting leucine and valine.Other primary literatureHuman & animalActiveFood & function2023
Zhou X, Zhang J, Shen J, et al.
Branched-chain amino acid biosynthesis in fungi.Other primary literatureUnknownActiveEssays in biochemistry2023
Steyer JT, Todd RB
Evaluation of branched-chain amino acid interactions in 10 to 20 kg nursery pigs using a central composite design.Other primary literatureAnimalActiveJournal of animal science2023
Humphrey DC, Haydon K, Greiner LL
DROUGHT-INDUCED BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE enhances drought tolerance in rice.Other primary literatureUnknownActivePlant physiology2023
Shim JS, Jeong HI, Bang SW, et al.
Proximity-dependent biotin identification links cholesterol catabolism with branched-chain amino acid degradation in Mycobacterium smegmatis.Other primary literatureAnimalActiveFASEB journal : official publication of the Federation of American Societies for Experimental Biology2023
Veyron-Churlet R, Lecher S, Lacoste AS, et al.
Aberrant branched-chain amino acid accumulation along the microbiota-gut-brain axis: Crucial targets affecting the occurrence and treatment of ischaemic stroke.Other primary literatureAnimalActiveBritish journal of pharmacology2023
Shen J, Guo H, Liu S, et al.
Systematic review with meta-analysis: Branched-chain amino acid supplementation in liver disease.Meta-analysisHumanActiveEuropean journal of clinical investigation2023
van Dijk AM, Bruins Slot AS, Portincasa P, et al.
The impact of branched-chain amino acid supplementation on measures of glucose homeostasis in individuals with hepatic disorders: A systematic review of clinical studies.Systematic reviewHumanActiveJournal of human nutrition and dietetics : the official journal of the British Dietetic Association2023
Prokopidis K, Kirwan RP, Giannos P, et al.
High doses of rosuvastatin induce impaired branched-chain amino acid catabolism and lead to insulin resistance.Other primary literatureAnimalActiveExperimental physiology2023
Bai X, Long X, Song F, et al.
Differential plasma branched-chain amino acid responses following the consumption of Greek-style yogurt and skimmed milk.Other primary literatureAnimalActiveApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2023
Brown JK, Perry CGR, Prior ET, et al.
Defective muscle ketone body oxidation disrupts BCAA catabolism by altering mitochondrial branched-chain aminotransferase.Other primary literatureHuman & animalActiveAmerican journal of physiology. Endocrinology and metabolism2023
Mechchate H, Abdualkader AM, Bernacchi JB, et al.
PPARβ/δ Agonism with GW501516 Increases Myotube PGC-1α Content and Reduces BCAA Media Content Independent of Changes in BCAA Catabolic Enzyme Expression.Other primary literatureUnknownActivePPAR research2023
Rivera CN, Hinkle JS, Watne RM, et al.
The effect of branched-chain amino acid supplementation on cancer treatment.ReviewHumanActiveNutrition and health2023
Lee K, Blanton C
Plasma Branched-Chain Amino Acid Concentrations and Glucose Homeostasis in Kidney Transplant Recipients and Candidates.Other primary literatureUnknownActiveCanadian journal of kidney health and disease2023
Prasad GVR, Nash MM, Yuan W, et al.
Human acute leukemia uses branched-chain amino acid catabolism to maintain stemness through regulating PRC2 function.Other primary literatureHumanActiveBlood advances2023
Kikushige Y, Miyamoto T, Kochi Y, et al.
GPRC5C drives branched-chain amino acid metabolism in leukemogenesis.Other primary literatureHuman & animalActiveBlood advances2023
Zhang YW, Velasco-Hernandez T, Mess J, et al.
β-aminoisobutyrics acid, a metabolite of BCAA, activates the AMPK/Nrf-2 pathway to prevent ferroptosis and ameliorates lung ischemia-reperfusion injury.Other primary literatureAnimalActiveMolecular medicine (Cambridge, Mass.)2023
Zhang Z, Li X, Guo J, et al.
Disrupted cardiac fibroblast BCAA catabolism contributes to diabetic cardiomyopathy via a periostin/NAP1L2/SIRT3 axis.Other primary literatureHuman & animalActiveCellular & molecular biology letters2023
Lu QB, Fu X, Liu Y, et al.
Effects of branched-chain amino acids on Shiraia perylenequinone production in mycelium cultures.Other primary literatureUnknownActiveMicrobial cell factories2023
Shen WH, Cong RP, Li XP, et al.
Characterization and application of a lactate and branched chain amino acid metabolism related gene signature in a prognosis risk model for multiple myeloma.Other primary literatureUnknownActiveCancer cell international2023
Yu Z, Qiu B, Zhou H, et al.
Empagliflozin ameliorates diabetic cardiomyopathy via regulated branched-chain amino acid metabolism and mTOR/p-ULK1 signaling pathway-mediated autophagy.Other primary literatureUnknownActiveDiabetology & metabolic syndrome2023
Zhang L, Zhang H, Xie X, et al.
Impaired Adipocyte SLC7A10 Promotes Lipid Storage in Association With Insulin Resistance and Altered BCAA Metabolism.Other primary literatureHuman & animalActiveThe Journal of clinical endocrinology and metabolism2023
Jersin RÅ, Sri Priyanka Tallapragada D, Skartveit L, et al.
Defective branched-chain amino acid catabolism in dorsal root ganglia contributes to mechanical pain.Other primary literatureHuman & animalActiveEMBO reports2023
Xie H, Li J, Lian N, et al.
Branched-chain amino acid synthesis is coupled to TOR activation early in the cell cycle in yeast.Other primary literatureUnknownActiveEMBO reports2023
Blank HM, Reuse C, Schmidt-Hohagen K, et al.
BCAA insufficiency leads to premature ovarian insufficiency via ceramide-induced elevation of ROS.Other primary literatureHuman & animalActiveEMBO molecular medicine2023
Guo X, Zhu Y, Guo L, et al.
[Effects of branched-chain amino acid supplementation on skeletal muscle proteolytic pathways after exercise-induced muscle injury in rats].Other primary literatureAnimalActiveWei sheng yan jiu = Journal of hygiene research2023
Wei H, Shi Y, Cheng Y, et al.
The Influence of Branched-Chain Amino Acid Supplementation on Fatigue and Tryptophan Metabolism After Acute and Chronic Exercise in Older Adults: Protocol for a Pilot Randomized Controlled Trial.Other primary literatureUnknownActiveJMIR research protocols2023
Robbins RN, Cortes T, O'Connor JC, et al.
Insulin Resistance and Impaired Branched-Chain Amino Acid Metabolism in Alzheimer's Disease.ReviewAnimalActiveJournal of Alzheimer's disease : JAD2023
Liu R, Zhang L, You H
Research progress on branched-chain amino acid aminotransferases.ReviewUnknownActiveFrontiers in genetics2023
Chen C, Naveed H, Chen K
The efficacy of branched-chain amino acid granules to restore phagocytic activity in cirrhosis patients, a randomized controlled trial.Other primary literatureUnknownActiveFrontiers in nutrition2023
Chamroonkul N, Rujeerapaiboon N, Sripongpun P, et al.
Acute consumption of a branched chain amino acid and vitamin B-6 containing sports drink does not improve multiple sprint exercise performance, but increases post-exercise blood glucose.Other primary literatureUnknownActiveFrontiers in nutrition2023
Farra SD
Crosstalk between arginine, glutamine, and the branched chain amino acid metabolism in the tumor microenvironment.ReviewUnknownActiveFrontiers in oncology2023
Wetzel TJ, Erfan SC, Figueroa LD, et al.
Empowering frail older adults: multicomponent elastic-band exercises and BCAA supplementation unleash physical health and preserve haematological biomarkers.Other primary literatureUnknownActiveFrontiers in sports and active living2023
Caldo-Silva A, Furtado GE, Chupel MU, et al.
Divergent Survival Outcomes Associated with Elevated Branched-Chain Amino Acid Levels among Older Adults with or without Hypertension and Diabetes: A Validated, Prospective, Longitudinal Follow-Up Study.Other primary literatureHumanActiveBiomolecules2023
Fung E, Ng KH, Kwok T, et al.
Specific Alteration of Branched-Chain Amino Acid Profile in Polycystic Ovary Syndrome.Other primary literatureUnknownActiveBiomedicines2023
Paczkowska K, Rachoń D, Berg A, et al.
The Role of Branched-Chain Amino Acid Supplementation in Combination with Locoregional Treatments for Hepatocellular Carcinoma: Systematic Review and Meta-Analysis.ReviewUnknownActiveCancers2023
Sideris GA, Tsaramanidis S, Vyllioti AT, et al.
Branched Chain Amino Acid Content and Antioxidant Activity of Mung Bean Tempeh Powder for Developing Oral Nutrition Supplements.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2023
Yanti, Violina V, Putri CE, et al.
Effects of Long-Term Physical Activity and BCAA Availability on the Subcellular Associations between Intramyocellular Lipids, Perilipins and PGC-1α.Other primary literatureHumanActiveInternational journal of molecular sciences2023
Fachada V, Silvennoinen M, Sahinaho UM, et al.
Short-Term Decreasing and Increasing Dietary BCAA Have Similar, but Not Identical Effects on Lipid and Glucose Metabolism in Lean Mice.Other primary literatureAnimalActiveInternational journal of molecular sciences2023
Sun Y, Sun B, Wang Z, et al.
Branched-Chain Amino Acid Assembly into Amyloid-like Fibrils Provides a New Paradigm for Maple Syrup Urine Disease Pathology.Other primary literatureHumanActiveInternational journal of molecular sciences2023
Kreiser T, Sogolovsky-Bard I, Zaguri D, et al.
The Virulence Factor Macrophage Infectivity Potentiator (Mip) Influences Branched-Chain Amino Acid Metabolism and Pathogenicity of Legionella pneumophila.Other primary literatureUnknownActiveMetabolites2023
Nikolka F, Karagöz MS, Nassef MZ, et al.
The Preventive Effect of Exercise and Oral Branched-Chain Amino Acid Supplementation on Obesity-Induced Brain Changes in Ldlr-/-.Leiden Mice.Other primary literatureAnimalActiveNutrients2023
Lohkamp KJ, van den Hoek AM, Solé-Guardia G, et al.
Vitamin D Supplementation Influences Ultramarathon-Induced Changes in Serum Amino Acid Levels, Tryptophan/Branched-Chain Amino Acid Ratio, and Arginine/Asymmetric Dimethylarginine Ratio.Randomized controlled trialHumanActiveNutrients2023
Mieszkowski J, Brzezińska P, Stankiewicz B, et al.
Genome-Wide Association Studies Using 3VmrMLM Model Provide New Insights into Branched-Chain Amino Acid Contents in Rice Grains.Other primary literatureUnknownActivePlants (Basel, Switzerland)2023
Sui Y, Che Y, Zhong Y, et al.
Diagnostic value of methylated branched chain amino acid transaminase 1/IKAROS family zinc finger 1 for colorectal cancer.Other primary literatureHumanActiveWorld journal of gastroenterology2023
Xu K, Yu AR, Pan SB, et al.
Comparison of an Antioxidant Source and Antioxidant Plus BCAA on Athletic Performance and Post Exercise Recovery of HorsesOther primary literatureUnknownUnknownJournal of equine veterinary science2023
Kent E, Coleman S, Bruemmer J, et al.
Portulaca oleracea L. Extract Alleviated Type 2 Diabetes Via Modulating the Gut Microbiota and Serum Branched-Chain Amino Acid Metabolism.Other primary literatureAnimalActiveMolecular nutrition & food research2022
Bao M, Hou K, Xin C, et al.
Branched-chain amino acid supplementation impairs insulin sensitivity and promotes lipogenesis during exercise in diet-induced obese mice.Other primary literatureAnimalActiveObesity (Silver Spring, Md.)2022
Zhang H, Xiang L, Huo M, et al.
Obesity, exercise training, and BCAA supplementation: All that glitters (may not be) gold.Other primary literatureHumanActiveObesity (Silver Spring, Md.)2022
Carter SJ, Long EB, Perry CA
Effects of branched-chain amino acid-rich supplementation on EWGSOP2 criteria for sarcopenia in older adults: a systematic review and meta-analysis.Meta-analysisHumanActiveEuropean journal of nutrition2022
Bai GH, Tsai MC, Tsai HW, et al.
Effects of maternal branched-chain amino acid and alanine supplementation on growth and biomarkers of protein metabolism in dams fed a low-protein diet and their offspring.Other primary literatureAnimalActiveAmino acids2022
Choi W, Kim J, Ko JW, et al.
An evaluation of elevated branched-chain amino acid inclusions on the performance of broiler chickens offered reduced-crude protein, wheat-based diets from 7 to 28 days post-hatchOther primary literatureUnknownUnknownAnimal feed science and technology2022
Greenhalgh S, Macelline SP, Chrystal PV, et al.
Elevated branched-chain amino acid inclusions generate distinctly divergent growth performance responses in broiler chickens offered wheat- and/or sorghum-based, reduced-crude protein dietsOther primary literatureUnknownUnknownAnimal feed science and technology2022
Greenhalgh S, Macelline SP, Chrystal PV, et al.
AICAR stimulates mitochondrial biogenesis and BCAA catabolic enzyme expression in C2C12 myotubes.Other primary literatureHumanActiveBiochimie2022
Hinkle JS, Rivera CN, Vaughan RA
Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression.Other primary literatureHumanActiveCell reports2022
Yang D, Liu H, Cai Y, et al.
Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure.Other primary literatureHumanActiveCell metabolism2022
Murashige D, Jung JW, Neinast MD, et al.
The early reduction of left ventricular mass after sleeve gastrectomy depends on the fall of branched-chain amino acid circulating levels.Other primary literatureHuman & animalActiveEBioMedicine2022
Castagneto-Gissey L, Angelini G, Mingrone G, et al.
Sarcojoint®, the branched-chain amino acid-based supplement, plus resistance exercise improved muscle mass in adults aged 50 years and older: A double-blinded randomized controlled trial.Randomized controlled trialHumanActiveExperimental gerontology2022
Peng LN, Yu PC, Hsu CC, et al.
Acetolactate synthases regulatory subunit and catalytic subunit genes VdILVs are involved in BCAA biosynthesis, microscletotial and conidial formation and virulence in Verticillium dahliae.Other primary literatureUnknownActiveFungal genetics and biology : FG & B2022
Shao S, Li B, Sun Q, et al.
Characterization of a lactic acid bacteria using branched-chain amino acid transaminase and protease from Jinhua Ham and application in myofibrillar protein model.Other primary literatureUnknownActiveMeat science2022
Liu R, Lu C, Wang Y, et al.
Branched-chain amino acid transaminase 1 inhibition attenuates childhood asthma in mice by effecting airway remodeling and autophagy.Other primary literatureAnimalActiveRespiratory physiology & neurobiology2022
Li J, Chen M, Lu L, et al.
Effect of the <i>BCAT2</i> polymorphism (rs11548193) on plasma branched-chain amino acid concentrations after dietary intervention in subjects with obesity and insulin resistance.Other primary literatureHumanActiveThe British journal of nutrition2022
González-Salazar LE, Granados-Portillo O, Medina-Vera I, et al.
Novel Branched-Chain Amino Acid-Catabolism Related Gene Signature for Overall Survival Prediction of Pancreatic Carcinoma.Other primary literatureHumanActiveJournal of proteome research2022
Jiang Z, Zheng J, Liu J, et al.
BCAT1 promotes osteoclast maturation by regulating branched-chain amino acid metabolism.Other primary literatureAnimalActiveExperimental & molecular medicine2022
Go M, Shin E, Jang SY, et al.
Role of branched-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCAA metabolism in type 2 diabetes.ReviewHuman & animalActiveNutrition & diabetes2022
Vanweert F, Schrauwen P, Phielix E
Excessive branched-chain amino acid accumulation restricts mesenchymal stem cell-based therapy efficacy in myocardial infarction.Other primary literatureHumanActiveSignal transduction and targeted therapy2022
Zhang F, Hu G, Chen X, et al.
ANGPTL4 negatively regulates the progression of osteosarcoma by remodeling branched-chain amino acid metabolism.Other primary literatureUnknownActiveCell death discovery2022
Lin S, Miao Y, Zheng X, et al.
Biosensor for branched-chain amino acid metabolism in yeast and applications in isobutanol and isopentanol production.Other primary literatureUnknownActiveNature communications2022
Zhang Y, Cortez JD, Hammer SK, et al.
A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes.Randomized controlled trialHumanActiveNature communications2022
Vanweert F, Neinast M, Tapia EE, et al.
BCAA-BCKA axis regulates WAT browning through acetylation of PRDM16.Other primary literatureAnimalActiveNature metabolism2022
Ma QX, Zhu WY, Lu XC, et al.
Gut Parabacteroides merdae protects against cardiovascular damage by enhancing branched-chain amino acid catabolism.Other primary literatureHuman & animalCorrectedNature metabolism2022
Qiao S, Liu C, Sun L, et al.
Metabolon formation regulates branched-chain amino acid oxidation and homeostasis.Other primary literatureAnimalActiveNature metabolism2022
Patrick M, Gu Z, Zhang G, et al.
Effect of Branched-Chain Amino Acid Infusion on In-Hospital Mortality of Patients With Hepatic Encephalopathy and End-Stage Kidney Disease: A Retrospective Cohort Study Using a National Inpatient Database.Other primary literatureHumanActiveJournal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation2022
Okada A, Yamana H, Yamaguchi S, et al.
Omega-3 fatty acids enhance the beneficial effect of BCAA supplementation on muscle function following eccentric contractions.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2022
Tsuchiya Y, Yanagimoto K, Sunagawa N, et al.
BDK knockout skeletal muscle satellite cells exhibit enhanced protein translation initiation signal in response to BCAA in vitro.Other primary literatureAnimalActiveBioscience, biotechnology, and biochemistry2022
Nakai N, Iida N, Kitai S, et al.
Chronically elevated branched chain amino acid levels are pro-arrhythmic.Other primary literatureHuman & animalActiveCardiovascular research2022
Portero V, Nicol T, Podliesna S, et al.
Association of Modifiable Lifestyle Factors with Plasma Branched-Chain Amino Acid Metabolites in Women.Other primary literatureHumanActiveThe Journal of nutrition2022
Hamaya R, Mora S, Lawler PR, et al.
Diet high in branched-chain amino acid promotes PDAC development by USP1-mediated BCAT2 stabilization.Other primary literatureUnknownActiveNational science review2022
Li JT, Li KY, Su Y, et al.
Branched-chain amino acid supplementation suppresses the detraining-induced reduction of mitochondrial content in mouse skeletal muscle.Other primary literatureAnimalActiveFASEB journal : official publication of the Federation of American Societies for Experimental Biology2022
Matsunaga Y, Tamura Y, Takahashi K, et al.
Association of branched-chain amino acid intake trajectory in adulthood with the risk of type 2 diabetes and its related risk factors.Other primary literatureHumanActiveChinese medical journal2022
Wang W, Han T, Hou W, et al.
Protein restriction and branched-chain amino acid restriction promote geroprotective shifts in metabolism.ReviewUnknownActiveAging cell2022
Trautman ME, Richardson NE, Lamming DW
Reprograming of proteasomal degradation by branched chain amino acid metabolism.Other primary literatureAnimalActiveAging cell2022
Ravanelli S, Li Q, Annibal A, et al.
Discovery of inhibitors against mycobacterium branched-chain amino acid aminotransferases through in silico screening and experimental evaluation.Other primary literatureUnknownActiveLetters in applied microbiology2022
Pham MT, Tran TTA, Zayabaatar E
Arabidopsis ACYL-ACTIVATING ENZYME 9 (AAE9) encoding an isobutyl-CoA synthetase is a key factor connecting branched-chain amino acid catabolism with iso-branched wax biosynthesis.Other primary literatureUnknownActiveThe New phytologist2022
Li S, Yang X, Huang H, et al.
Improvement of Fusel Alcohol Production by Engineering of the Yeast Branched-Chain Amino Acid Aminotransaminase.Other primary literatureUnknownActiveApplied and environmental microbiology2022
Koonthongkaew J, Ploysongsri N, Toyokawa Y, et al.
BrnQ-Type Branched-Chain Amino Acid Transporters Influence Bacillus anthracis Growth and Virulence.Other primary literatureAnimalActivemBio2022
Dutta S, Corsi ID, Bier N, et al.
Mitochondrial H2S Regulates BCAA Catabolism in Heart Failure.Other primary literatureHuman & animalCorrectedCirculation research2022
Li Z, Xia H, Sharp TE 3rd, et al.
Unbreak My Heart: Restore H2S and Branched Chain Amino Acid Oxidation in the Mitochondria.Other primary literatureUnknownActiveCirculation research2022
Rao K, Shiva S
Systematic analysis of relationships between plasma branched-chain amino acid concentrations and cardiometabolic parameters: an association and Mendelian randomization study.Other primary literatureHumanActiveBMC medicine2022
Doestzada M, Zhernakova DV, C L van den Munckhof I, et al.
Intravenous administration of a branched-chain amino-acid-free solution in children and adults with acute decompensation of maple syrup urine disease: a prospective multicentre observational study.Observational studyHumanActiveOrphanet journal of rare diseases2022
Alili JM, Berleur MP, Husson MC, et al.
A multivariate Box-Behnken assessment of elevated branched-chain amino acid concentrations in reduced crude protein diets offered to male broiler chickens.Other primary literatureAnimalActivePloS one2022
Chrystal PV, Greenhalgh S, Macelline SP, et al.
New Evidence of Oral Branched-Chain Amino Acid Supplementation on the Prognosis of Patients With Advanced Liver Disease.Meta-analysisHumanActiveClinical and translational gastroenterology2022
Lee H, Yoo JJ, Ahn SH, et al.
Effects of dietary branched-chain amino acid supplementation on serum and milk metabolome profiles in dairy cows during early lactation.Other primary literatureHuman & animalActiveJournal of dairy science2022
Xu W, Kenéz Á, Mann S, et al.
Porphyromonas gingivalis Induces Increases in Branched-Chain Amino Acid Levels and Exacerbates Liver Injury Through livh/livk.Other primary literatureAnimalActiveFrontiers in cellular and infection microbiology2022
Wu L, Shi R, Bai H, et al.
Aberrant branched-chain amino acid catabolism in cardiovascular diseases.ReviewUnknownActiveFrontiers in cardiovascular medicine2022
Xiong Y, Jiang L, Li T
The Effect of Branched Chain Amino Acid Supplementation on Stroke-Related Sarcopenia.Other primary literatureUnknownActiveFrontiers in neurology2022
Park MK, Lee SJ, Choi E, et al.
Obesity by High-Fat Diet Increases Pain Sensitivity by Reprogramming Branched-Chain Amino Acid Catabolism in Dorsal Root Ganglia.Other primary literatureUnknownActiveFrontiers in nutrition2022
Lian N, Luo K, Xie H, et al.
Elevated BCAA Suppresses the Development and Metastasis of Breast Cancer.Other primary literatureUnknownActiveFrontiers in oncology2022
Chi R, Yao C, Chen S, et al.
The mechanism of branched-chain amino acid transferases in different diseases: Research progress and future prospects.ReviewUnknownActiveFrontiers in oncology2022
Nong X, Zhang C, Wang J, et al.
Evaluation of therapeutic strategies targeting BCAA catabolism using a systems pharmacology model.Other primary literatureUnknownActiveFrontiers in pharmacology2022
Voronova V, Sokolov V, Morias Y, et al.
Early Stepdown Weaning of Dairy Calves with Glutamine and Branched-Chain Amino Acid Supplementations.Other primary literatureUnknownActiveAnimals : an open access journal from MDPI2022
Wickramasinghe J, Kaya CA, Beitz D, et al.
Exercise Enhances Branched-Chain Amino Acid Catabolism and Decreases Cardiac Vulnerability to Myocardial Ischemic Injury.Other primary literatureHuman & animalActiveCells2022
Wu G, Guo Y, Li M, et al.
Loss of Eicosapentaenoic Acid (EPA) after Retort Sterilization of the EPA-BCAA Fortified Complete Nutrition Drink.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2022
Khoonin W, Shantavasinkul PC, Santivarangkna C, et al.
A Gain-of-Function Mutation on BCKDK Gene and Its Possible Pathogenic Role in Branched-Chain Amino Acid Metabolism.Other primary literatureHumanActiveGenes2022
Maguolo A, Rodella G, Giorgetti A, et al.
Association of Genetically Predicted BCAA Levels with Muscle Fiber Size in Athletes Consuming Protein.Other primary literatureHumanActiveGenes2022
Hall ECR, Semenova EA, Bondareva EA, et al.
Prepregnancy Protein Source and BCAA Intake Are Associated with Gestational Diabetes Mellitus in the CARDIA Study.Other primary literatureHuman & animalActiveInternational journal of environmental research and public health2022
Gadgil MD, Ingram KH, Appiah D, et al.
Role of Branched-Chain Amino Acid Metabolism in Type 2 Diabetes, Obesity, Cardiovascular Disease and Non-Alcoholic Fatty Liver Disease.ReviewHuman & animalActiveInternational journal of molecular sciences2022
Cuomo P, Capparelli R, Iannelli A, et al.
Branched-Chain Amino Acid Deprivation Decreases Lipid Oxidation and Lipogenesis in C2C12 Myotubes.Other primary literatureUnknownActiveMetabolites2022
Karvinen S, Fachada V, Sahinaho UM, et al.
Mild Endurance Exercise during Fasting Increases Gastrocnemius Muscle and Prefrontal Cortex Thyroid Hormone Levels through Differential BHB and BCAA-Mediated BDNF-mTOR Signaling in Rats.Other primary literatureAnimalActiveNutrients2022
Giacco A, Cioffi F, Cuomo A, et al.
Association between Branched-Chain Amino Acid Intake and Physical Function among Chinese Community-Dwelling Elderly Residents.Other primary literatureHumanActiveNutrients2022
Liao M, Mu Y, Su X, et al.
61 Effect of branched-chain amino acid and N-acetylcysteine supplementation post-exercise on muscle mTOR signaling in exercising horsesOther primary literatureUnknownUnknownJournal of equine veterinary science2022
Hauss A, Loos C, Gerritsen A, et al.
Titration of dietary isoleucine and evaluation of branched-chain amino acid levels in female Cobb 500 broilers during a 22- to 42-day finisher periodOther primary literatureUnknownUnknownJournal of Applied Poultry Research.2022
Maynard CW, Mullenix GJ, Maynard CJ, et al.
Production of butyrate and branched-chain amino acid catabolic byproducts by CHO cells in fed-batch culture enhances their specific productivity.Other primary literatureAnimalActiveBiotechnology and bioengineering2021
Harrington C, Jacobs M, Bethune Q, et al.
Easy clinical predictor for low BCAA to tyrosine ratio in chronic liver disease patients with hepatocellular carcinoma: Usefulness of ALBI score as nutritional prognostic marker.Other primary literatureHumanActiveCancer medicine2021
Hiraoka A, Kato M, Marui K, et al.
Impact of lifestyle Intervention on branched-chain amino acid catabolism and insulin sensitivity in adolescents with obesity.Other primary literatureHumanActiveEndocrinology, diabetes & metabolism2021
Jachthuber Trub C, Balikcioglu M, Freemark M, et al.
Enhanced small neutral but not branched chain amino acid transport after epigenetic sodium coupled neutral amino acid transporter-2 (SNAT2) cDNA expression in myoblasts.Other primary literatureUnknownActiveJournal of cachexia, sarcopenia and muscle2021
Pearson T, Wendowski O, Powell PP
Gut barrier and microbiota changes with glycine and branched-chain amino acid supplementation in chronic haemodialysis patients.Randomized controlled trialHumanActiveJournal of cachexia, sarcopenia and muscle2021
Genton L, Pruijm M, Teta D, et al.
Real-world management of maple syrup urine disease (MSUD) metabolic decompensations with branched chain amino acid-free formulas in France and Germany: A retrospective observational study.Other primary literatureUnknownActiveJIMD reports2021
de Lonlay P, Posset R, Mütze U, et al.
Regulation of branched-chain amino acid metabolism by hypoxia-inducible factor in glioblastoma.Other primary literatureHumanActiveCellular and molecular life sciences : CMLS2021
Zhang B, Chen Y, Shi X, et al.
Branched-chain amino acid metabolism, insulin sensitivity and liver fat response to exercise training in sedentary dysglycaemic and normoglycaemic men.Other primary literatureHumanActiveDiabetologia2021
Lee S, Gulseth HL, Langleite TM, et al.
Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes.Other primary literatureHuman & animalActiveDiabetologia2021
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An overview of branched-chain amino acid aminotransferases: functional differences between mitochondrial and cytosolic isozymes in yeast and human.ReviewHumanActiveApplied microbiology and biotechnology2021
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Aerial ammonia exposure induces the perturbation of the interorgan ammonia disposal and branched-chain amino acid catabolism in growing pigs.Other primary literatureUnknownActiveAnimal nutrition (Zhongguo xu mu shou yi xue hui)2021
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Aberrant BCAA and glutamate metabolism linked to regional neurodegeneration in a mouse model of Leigh syndrome.Other primary literatureAnimalActiveBiochimica et biophysica acta. Molecular basis of disease2021
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PPARγ-induced upregulation of subcutaneous fat adiponectin secretion, glyceroneogenesis and BCAA oxidation requires mTORC1 activity.Other primary literatureAnimalActiveBiochimica et biophysica acta. Molecular and cell biology of lipids2021
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SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis.Other primary literatureAnimalActiveCell reports2021
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The glutathionylation agent disulfiram augments superoxide/hydrogen peroxide production when liver mitochondria are oxidizing ubiquinone pool-linked and branched chain amino acid substrates.Other primary literatureUnknownActiveFree radical biology & medicine2021
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Bacteroides spp. promotes branched-chain amino acid catabolism in brown fat and inhibits obesity.Other primary literatureUnknownActiveiScience2021
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Branched-chain amino acid metabolism controls membrane phospholipid structure in Staphylococcus aureus.Other primary literatureUnknownActiveThe Journal of biological chemistry2021
Frank MW, Whaley SG, Rock CO
Disordered branched chain amino acid catabolism in pancreatic islets is associated with postprandial hypersecretion of glucagon in diabetic mice.Other primary literatureAnimalActiveThe Journal of nutritional biochemistry2021
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Branched-chain amino acid supplementation improves cycling performance in untrained cyclists.Randomized controlled trialHumanActiveJournal of science and medicine in sport2021
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Does branched-chain amino acid supplementation improve pulmonary rehabilitation effect in COPD?Randomized controlled trialHumanActiveRespiratory medicine2021
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Differences in gene expression of enzymes involved in branched-chain amino acid metabolism of abdominal subcutaneous adipose tissue between pregnant women with and without PCOS.Other primary literatureHumanActiveTaiwanese journal of obstetrics & gynecology2021
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Assessment of the Clinical Impact of a Liver-Specific, BCAA-Enriched Diet in Major Liver Surgery.Randomized controlled trialHumanActiveTransplantation proceedings2021
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Disrupted branched-chain amino acid catabolism impair cardiac insulin signaling and is associated with adverse cardiometabolic outcomes.Other primary literatureHuman & animalActiveJournal of molecular and cellular cardiology2021
Biswas D, Pulinilkunnil T
Hypoglycemic Effect of Hydrophobic BCAA Peptides Is Associated with Altered PI3K/Akt Protein Expression.Other primary literatureAnimalActiveJournal of agricultural and food chemistry2021
Zhu X, Wang W, Cui C
Branched-chain amino acid aminotransferase 2 regulates ferroptotic cell death in cancer cells.Other primary literatureHuman & animalActiveCell death and differentiation2021
Wang K, Zhang Z, Tsai HI, et al.
BCAT1 decreases the sensitivity of cancer cells to cisplatin by regulating mTOR-mediated autophagy via branched-chain amino acid metabolism.Other primary literatureHuman & animalActiveCell death & disease2021
Luo L, Sun W, Zhu W, et al.
Krüppel-like factor 6-mediated loss of BCAA catabolism contributes to kidney injury in mice and humans.Other primary literatureHuman & animalActiveProceedings of the National Academy of Sciences of the United States of America2021
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Effects of PPM1K rs1440581 and rs7678928 on serum branched-chain amino acid levels and risk of cardiovascular disease.Other primary literatureHumanActiveAnnals of medicine2021
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Molecular and biochemical investigations of inborn errors of metabolism-altered redox homeostasis in branched-chain amino acid disorders, organic acidurias, and homocystinuria.ReviewHuman & animalActiveFree radical research2021
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Branched-Chain Amino Acid Supplementation Does Not Preserve Lean Mass or Affect Metabolic Profile in Adults with Overweight or Obesity in a Randomized Controlled Weight Loss Intervention.Randomized controlled trialHumanActiveThe Journal of nutrition2021
Ooi DSQ, Ling JQR, Sadananthan SA, et al.
The branched-chain amino acid aminotransferase TaBCAT1 modulates amino acid metabolism and positively regulates wheat rust susceptibility.Other primary literatureUnknownActiveThe Plant cell2021
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A branched-chain amino acid-based metabolic score can predict liver fat in children and adolescents with severe obesity.Other primary literatureHumanActivePediatric obesity2021
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Branched-chain amino acid synthesis and glucosinolate-myrosinase system during takuan-zuke processing of radish root.Other primary literatureUnknownCorrectedJournal of food biochemistry.2021
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Phenylbutyrate, a branched-chain amino acid keto dehydrogenase activator, promotes branched-chain amino acid metabolism and induces muscle catabolism in C2C12 cells.Other primary literatureAnimalActiveExperimental physiology2021
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Isolated Leucine and Branched-Chain Amino Acid Supplementation for Enhancing Muscular Strength and Hypertrophy: A Narrative Review.ReviewHumanActiveInternational journal of sport nutrition and exercise metabolism2021
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Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans.Other primary literatureUnknownActivemBio2021
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The effect of branched-chain amino acid on muscle damage markers and performance following strenuous exercise: a systematic review and meta-analysis.Meta-analysisHumanActiveApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2021
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Metabolic flux analysis of branched-chain amino and keto acids (BCAA, BCKA) and β-hydroxy β-methylbutyric acid across multiple organs in the pig.Other primary literatureAnimalActiveAmerican journal of physiology. Endocrinology and metabolism2021
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Markers of branched-chain amino acid catabolism are not affected by exercise training in pregnant women with obesity.Randomized controlled trialHumanActiveJournal of applied physiology (Bethesda, Md. : 1985)2021
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Association of Plasma Branched-Chain Amino Acid With Biomarkers of Inflammation and Lipid Metabolism in Women.Other primary literatureHumanActiveCirculation. Genomic and precision medicine2021
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A higher bacterial inward BCAA transport driven by Faecalibacterium prausnitzii is associated with lower serum levels of BCAA in early adolescents.Other primary literatureHumanActiveMolecular medicine (Cambridge, Mass.)2021
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Disturbances in branched-chain amino acid profile and poor daily functioning in mildly depressed chronic obstructive pulmonary disease patients.Other primary literatureHumanActiveBMC pulmonary medicine2021
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Severe anemia in patients with Propionic acidemia is associated with branched-chain amino acid imbalance.Other primary literatureHumanActiveOrphanet journal of rare diseases2021
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Comparative study of the effect of neuromuscular electrical stimulation and oral administration of branched-chain amino acid on preventing sarcopenia in patients after living-donor liver transplantation: study protocol for an open-label randomized controlled trial.Other primary literatureHumanActiveTrials2021
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Significance of serum branched-chain amino acid to tyrosine ratio measurement in athletes with high skeletal muscle mass.Other primary literatureUnknownActiveBMC sports science, medicine & rehabilitation2021
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Dietary branched-chain amino acid assessment in broilers from 22 to 35 days of age.Other primary literatureUnknownActiveJournal of animal science and biotechnology2021
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Elevated Plasma Branched-Chain Amino Acid Levels Correlate With Type 2 Diabetes-Related Metabolic Disturbances.Observational studyHumanActiveThe Journal of clinical endocrinology and metabolism2021
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BCAA Supplementation in Mice with Diet-induced Obesity Alters the Metabolome Without Impairing Glucose Homeostasis.Other primary literatureAnimalActiveEndocrinology2021
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Role of Branched-chain Amino Acid Metabolism in Tumor Development and Progression.ReviewUnknownActiveJournal of cancer prevention2021
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Enrichment of branched chain amino acid transaminase 1 correlates with multiple biological processes and contributes to poor survival of IDH1 wild-type gliomas.Other primary literatureHumanActiveAging2021
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GEO data mining and TCGA analysis reveal altered branched chain amino acid metabolism in pancreatic cancer patients.Other primary literatureHumanActiveAging2021
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Pancreatic stellate cells regulate branched-chain amino acid metabolism in pancreatic cancer.Other primary literatureUnknownActiveAnnals of translational medicine2021
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Expression of specific signaling components related to muscle protein turnover and of branched-chain amino acid catabolic enzymes in muscle and adipose tissue of preterm and term calves.Other primary literatureAnimalActiveJournal of dairy science2021
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Branched-Chain Amino Acid Catabolism and Cardiopulmonary Function Following Acute Maximal Exercise Testing in Adolescents.Other primary literatureUnknownActiveFrontiers in cardiovascular medicine2021
Gumus Balikcioglu P, Ramaker ME, Mason KA, et al.
Functional Metabolic Mapping Reveals Highly Active Branched-Chain Amino Acid Metabolism in Human Astrocytes, Which Is Impaired in iPSC-Derived Astrocytes in Alzheimer's Disease.Other primary literatureUnknownActiveFrontiers in aging neuroscience2021
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Impact of Branched Chain Amino Acid on Muscle Mass, Muscle Strength, Physical Performance, Combined Survival, and Maintenance of Liver Function Changes in Laboratory and Prognostic Markers on Sarcopenic Patients With Liver Cirrhosis (BCAAS Study): A Randomized Clinical Trial.Other primary literatureUnknownActiveFrontiers in nutrition2021
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Pyridostigmine Protects Against Diabetic Cardiomyopathy by Regulating Vagal Activity, Gut Microbiota, and Branched-Chain Amino Acid Catabolism in Diabetic Mice.Other primary literatureUnknownActiveFrontiers in pharmacology2021
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Branched-Chain Amino Acid Supplementation Alters the Abundance of Mechanistic Target of Rapamycin and Insulin Signaling Proteins in Subcutaneous Adipose Explants from Lactating Holstein Cows.Other primary literatureUnknownActiveAnimals : an open access journal from MDPI2021
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Gut Microbiota as the Link between Elevated BCAA Serum Levels and Insulin Resistance.ReviewHumanActiveBiomolecules2021
Gojda J, Cahova M
Serum Branched-Chain Amino Acid Metabolites Increase in Males When Aerobic Exercise Is Initiated with Low Muscle Glycogen.Other primary literatureUnknownActiveMetabolites2021
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Effect of Training-Detraining Phases of Multicomponent Exercises and BCAA Supplementation on Inflammatory Markers and Albumin Levels in Frail Older Persons.Randomized controlled trialHumanActiveNutrients2021
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Higher Branched-Chain Amino Acid Intake Is Associated with Handgrip Strength among Korean Older Adults.Other primary literatureHumanActiveNutrients2021
Park S, Chae M, Park H, et al.
Branched Chain Amino Acid Supplementation to a Hypocaloric Diet Does Not Affect Resting Metabolic Rate but Increases Postprandial Fat Oxidation Response in Overweight and Obese Adults after Weight Loss Intervention.Randomized controlled trialHumanActiveNutrients2021
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Plasma Changes of Branched-Chain Amino Acid in Patients with Esophageal Cancer.Other primary literatureUnknownActiveMiddle East journal of digestive diseases2021
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Association between dietary branched-chain amino acid intake and skeletal muscle mass index among Korean adults: Interaction with obesity.Other primary literatureUnknownActiveNutrition research and practice2021
Chae M, Park HS, Park K
Is branched-chain amino acid nutritional supplementation beneficial or detrimental in heart failure?ReviewUnknownActiveWorld journal of cardiology2021
Narita K, Amiya E
Metabolic flexibility via mitochondrial BCAA carrier SLC25A44 is required for optimal fever.Other primary literatureAnimalActiveeLife2021
Yoneshiro T, Kataoka N, Walejko JM, et al.
Influence of branched chain amino acid inclusion in diets varying in ingredient composition on broiler performance, processing yields, and pododermatitis and litter characteristicsOther primary literatureUnknownUnknownJournal of Applied Poultry Research.2021
Lee DT, Lee JT, Rochell SJ
Responses to graded levels of leucine and branched-chain amino acid imbalance in tiger puffer Takifugu rubripesOther primary literatureUnknownUnknownAquaculture.2021
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Branched-chain amino acid supplementation for improving growth and development in term and preterm neonates.Systematic reviewHumanActiveThe Cochrane database of systematic reviews2020
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Effect of metformin on myotube BCAA catabolism.Other primary literatureAnimalActiveJournal of cellular biochemistry2020
Rivera ME, Lyon ES, Vaughan RA
Branched-chain amino acid to tyrosine ratio is an essential pre-treatment factor for maintaining sufficient treatment intensity of lenvatinib in patients with hepatocellular carcinoma.Other primary literatureHumanActiveJournal of hepato-biliary-pancreatic sciences2020
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Cardiometabolic risk factor clustering in patients with deficient branched-chain amino acid catabolism: A case-control study.Observational studyHumanActiveJournal of inherited metabolic disease2020
Gancheva S, Caspari D, Bierwagen A, et al.
Daily Branched-Chain Amino Acid Intake and Risks of Obesity and Insulin Resistance in Children: A Cross-Sectional Study.Other primary literatureHumanActiveObesity (Silver Spring, Md.)2020
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Fungal elicitor-induced transcriptional changes of genes related to branched-chain amino acid metabolism in Streptomyces natalensis HW-2.Other primary literatureUnknownActiveApplied microbiology and biotechnology2020
Shen W, Wang D, Wei L, et al.
Effect of the Ala234Asp replacement in mitochondrial branched-chain amino acid aminotransferase on the production of BCAAs and fusel alcohols in yeast.Other primary literatureUnknownActiveApplied microbiology and biotechnology2020
Koonthongkaew J, Toyokawa Y, Ohashi M, et al.
Branched-chain amino acid catabolism of Thermoanaerobacter pseudoethanolicus reveals potential route to branched-chain alcohol formation.Other primary literatureUnknownActiveExtremophiles : life under extreme conditions2020
Scully SM, Orlygsson J
The Effect of One Anastomosis Gastric Bypass on Branched-Chain Fatty Acid and Branched-Chain Amino Acid Metabolism in Subjects with Morbid Obesity.Other primary literatureHumanActiveObesity surgery2020
Pakiet A, Wilczynski M, Rostkowska O, et al.
Emerging Roles for Branched-Chain Amino Acid Metabolism in Cancer.ReviewHumanActiveCancer cell2020
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Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion.Other primary literatureAnimalActiveCell reports2020
White PJ, Lapworth AL, McGarrah RW, et al.
PP2Cm overexpression alleviates MI/R injury mediated by a BCAA catabolism defect and oxidative stress in diabetic mice.Other primary literatureAnimalActiveEuropean journal of pharmacology2020
Lian K, Guo X, Wang Q, et al.
Dietary Luffa cylindrica (L.) Roem promotes branched-chain amino acid catabolism in the circulation system via gut microbiota in diet-induced obese mice.Other primary literatureAnimalActiveFood chemistry2020
Zhang L, Yue Y, Shi M, et al.
A biotechnological approach for the production of branched chain amino acid containing bioactive peptides to improve human health: A review.ReviewHumanActiveFood research international (Ottawa, Ont.)2020
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Usefulness of the plasma branched-chain amino acid/aromatic amino acid ratio for predicting future cardiac events in patients with heart failure.Other primary literatureHumanActiveJournal of cardiology2020
Hiraiwa H, Okumura T, Kondo T, et al.
Moderate intake of BCAA-rich protein improves glucose homeostasis in high-fat-fed mice.Other primary literatureHuman & animalActiveThe Journal of nutritional biochemistry2020
Roquetto AR, Moura CS, de Almeida Santos-Junior V, et al.
Branched-chain amino acid supplementation ameliorates angiotensin II-induced skeletal muscle atrophy.Other primary literatureAnimalActiveLife sciences2020
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Effects of high intensity interval training (up & downward running) with BCAA/nano chitosan on Foxo3 and SMAD soleus muscles of aging rat.Other primary literatureAnimalActiveLife sciences2020
Sadri S, Sharifi G, Jalali Dehkordi K
A high-protein diet, not isolated BCAA, is associated with skeletal muscle mass index in patients with gastrointestinal cancer.Observational studyHumanActiveNutrition (Burbank, Los Angeles County, Calif.)2020
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Branched-chain amino acid aminotransferase-1 regulates self-renewal and pluripotency of mouse embryonic stem cells through Ras signaling.Other primary literatureAnimalActiveStem cell research2020
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Lipid changes in the metabolome of a single case study with maple syrup urine disease (MSUD) after five days of improved diet adherence of controlled branched-chain amino acids (BCAA).Other primary literatureUnknownActiveMolecular genetics and metabolism reports2020
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Multifaceted role of branched-chain amino acid metabolism in cancer.ReviewHuman & animalActiveOncogene2020
Peng H, Wang Y, Luo W
Phosphorylation of BCKDK of BCAA catabolism at Y246 by Src promotes metastasis of colorectal cancer.Other primary literatureHuman & animalActiveOncogene2020
Tian Q, Yuan P, Quan C, et al.
Acetylation promotes BCAT2 degradation to suppress BCAA catabolism and pancreatic cancer growth.Other primary literatureHumanActiveSignal transduction and targeted therapy2020
Lei MZ, Li XX, Zhang Y, et al.
BCAT2-mediated BCAA catabolism is critical for development of pancreatic ductal adenocarcinoma.Other primary literatureHuman & animalActiveNature cell biology2020
Li JT, Yin M, Wang D, et al.
Loss of the branched-chain amino acid transporter CD98hc alters the development of colonic macrophages in mice.Other primary literatureHuman & animalActiveCommunications biology2020
Wuggenig P, Kaya B, Melhem H, et al.
Leucine and branched-chain amino acid metabolism contribute to the growth of bone sarcomas by regulating AMPK and mTORC1 signaling.Other primary literatureHumanActiveThe Biochemical journal2020
Martin SB, Reiche WS, Fifelski NA, et al.
Divergent Changes in Serum Branched-Chain Amino Acid Concentrations and Estimates of Insulin Resistance throughout Gestation in Healthy Women.Other primary literatureHumanActiveThe Journal of nutrition2020
Allman BR, Diaz EC, Andres A, et al.
Branched-Chain Amino Acid Fortification Does Not Restore Muscle Protein Synthesis Rates following Ingestion of Lower- Compared with Higher-Dose Mycoprotein.Randomized controlled trialHumanActiveThe Journal of nutrition2020
Monteyne AJ, Coelho MOC, Porter C, et al.
Branched-Chain Amino Acid Oxidation Is Elevated in Adults with Morbid Obesity and Decreases Significantly after Sleeve Gastrectomy.Other primary literatureHumanActiveThe Journal of nutrition2020
Tan HC, Hsu JW, Kovalik JP, et al.
Effect of branched-chain amino acid supplementation, dietary intake and circulating levels in cardiometabolic diseases: an updated review.ReviewHumanActiveCurrent opinion in clinical nutrition and metabolic care2020
de la O V, Zazpe I, Ruiz-Canela M
Switching from branched-chain amino acid granules to branched-chain amino acid-enriched nutrient improves the branched-chain amino acid-to-tyrosine ratio in patients with cirrhosis with hypoalbuminemia: a prospective study.Other primary literatureHumanActiveEuropean journal of gastroenterology & hepatology2020
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Novel function of transcription factor Uga3 as an activator of branched-chain amino acid permease BAP2 gene expression.Other primary literatureUnknownActiveMicrobiology (Reading, England)2020
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Outcomes of lactulose plus branched-chain amino acid infusion and lactulose alone for hepatic encephalopathy: A retrospective cohort study using a national inpatient database.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2020
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Astroglial biotin deprivation under endoplasmic reticulum stress uncouples BCAA-mTORC1 role in lipid synthesis to prolong autophagy inhibition in the aging brain.Other primary literatureAnimalActiveJournal of neurochemistry2020
Ganesan D, Ramaian Santhaseela A, Rajasekaran S, et al.
Natural variation in the OsbZIP18 promoter contributes to branched-chain amino acid levels in rice.Other primary literatureUnknownActiveThe New phytologist2020
Sun Y, Shi Y, Liu G, et al.
The Intermediates in Branched-Chain Amino Acid Biosynthesis Are Indispensable for Conidial Germination of the Insect-Pathogenic Fungus Metarhizium robertsii.Other primary literatureUnknownActiveApplied and environmental microbiology2020
Luo F, Zhou H, Zhou X, et al.
Dietary branched-chain amino acid restriction alters fuel selection and reduces triglyceride stores in hearts of Zucker fatty rats.Other primary literatureAnimalActiveAmerican journal of physiology. Endocrinology and metabolism2020
McGarrah RW, Zhang GF, Christopher BA, et al.
Branched-Chain Amino Acid Catabolism Promotes Thrombosis Risk by Enhancing Tropomodulin-3 Propionylation in Platelets.Other primary literatureHuman & animalActiveCirculation2020
Xu Y, Jiang H, Li L, et al.
Letter by Liu et al Regarding Article, "Branched-Chain Amino Acid Catabolism Promotes Thrombosis Risk by Enhancing Tropomodulin-3 Propionylation in Platelets".Other primary literatureHumanActiveCirculation2020
Liu X, Guo J, Yu H
Response by Xu et al to Letter Regarding Article, "Branched-Chain Amino Acid Catabolism Promotes Thrombosis Risk by Enhancing Tropomodulin-3 Propionylation in Platelets".Other primary literatureHumanActiveCirculation2020
Xu Y, Jiang H, Liu J
Porphyromonas gingivalis Induces Insulin Resistance by Increasing BCAA Levels in Mice.Other primary literatureAnimalActiveJournal of dental research2020
Tian J, Liu C, Zheng X, et al.
Eravacycline susceptibility was impacted by genetic mutation of 30S ribosome subunits, and branched-chain amino acid transport system II carrier protein, Na/Pi cotransporter family protein in Staphylococcus aureus.Other primary literatureHumanActiveBMC microbiology2020
Wang Z, Lin Z, Bai B, et al.
Prognostic significance of branched-chain amino acid transferase 1 and CD133 in triple-negative breast cancer.Other primary literatureHumanActiveBMC cancer2020
Song Y, Zhao B, Xu Y, et al.
Effects of a commercially available branched-chain amino acid-alanine-carbohydrate-based sports supplement on perceived exertion and performance in high intensity endurance cycling tests.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2020
Gervasi M, Sisti D, Amatori S, et al.
Excessive BCAA regulates fat metabolism partially through the modification of m6A RNA methylation in weanling piglets.Other primary literatureUnknownActiveNutrition & metabolism2020
Heng J, Wu Z, Tian M, et al.
Plasma BCAA Changes in Patients With NAFLD Are Sex Dependent.Other primary literatureHumanActiveThe Journal of clinical endocrinology and metabolism2020
Grzych G, Vonghia L, Bout MA, et al.
Branched-chain Amino Acid Catabolism by Brown Adipose Tissue.Other primary literatureUnknownActiveEndocrinology2020
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A pathogen branched-chain amino acid catabolic pathway subverts host survival by impairing energy metabolism and the mitochondrial UPR.Other primary literatureAnimalActivePLoS pathogens2020
Mahmud SA, Qureshi MA, Sapkota M, et al.
Dysfunctional oxidative phosphorylation shunts branched-chain amino acid catabolism onto lipogenesis in skeletal muscle.Other primary literatureAnimalActiveThe EMBO journal2020
Sánchez-González C, Nuevo-Tapioles C, Herrero Martín JC, et al.
Usefulness of Plasma Branched-Chain Amino Acid Analysis in Predicting Outcomes of Patients with Nonischemic Dilated Cardiomyopathy.Other primary literatureHumanActiveInternational heart journal2020
Kimura Y, Okumura T, Kazama S, et al.
Effects of enriched branched-chain amino acid supplementation on sarcopenia.Other primary literatureHumanActiveAging2020
Ko CH, Wu SJ, Wang ST, et al.
Effects of branched-chain amino acid supplement on knee peak torque and indicators of muscle damage following isokinetic exercise-induced delayed onset muscle soreness.Other primary literatureUnknownActivePhysical activity and nutrition2020
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Short-term branched-chain amino acid supplementation does not enhance vertical jump in professional volleyball players. A double-blind, controlled, randomized study.Randomized controlled trialHumanActiveNutricion hospitalaria2020
Martín-Martínez JP, Calleja Gonzalez J, Adsuar Sala JC, et al.
Short communication: Colostrum versus formula: Effects on mRNA expression of genes related to branched-chain amino acid metabolism in neonatal dairy calves.Other primary literatureAnimalActiveJournal of dairy science2020
Ghaffari MH, Sadri H, Hammon HM, et al.
Adverse Outcomes in Obese Cardiac Surgery Patients Correlates With Altered Branched-Chain Amino Acid Catabolism in Adipose Tissue and Heart.Other primary literatureHumanActiveFrontiers in endocrinology2020
Biswas D, Tozer K, Dao KT, et al.
MiR-125a-3p-KLF15-BCAA Regulates the Skeletal Muscle Branched-Chain Amino Acid Metabolism in Nile Tilapia (Oreochromis niloticus) During Starvation.Other primary literatureUnknownActiveFrontiers in genetics2020
Li H, An X, Bao L, et al.
Gentamicin Induced Microbiome Adaptations Associate With Increased BCAA Levels and Enhance Severity of Influenza Infection.Other primary literatureHuman & animalActiveFrontiers in immunology2020
Sun Y, He Z, Li J, et al.
Circulating Branched Chain Amino Acid Concentrations Are Higher in Dairy-Avoiding Females Following an Equal Volume of Sheep Milk Relative to Cow Milk: A Randomized Controlled Trial.Other primary literatureUnknownActiveFrontiers in nutrition2020
Milan AM, Samuelsson LM, Shrestha A, et al.
Consumption of a Branched-Chain Amino Acid (BCAA) during Days 2-10 of Pregnancy Causes Abnormal Fetal and Placental Growth: Implications for BCAA Supplementation in Humans.Other primary literatureHuman & animalActiveInternational journal of environmental research and public health2020
To CY, Freeman M, Van Winkle LJ
Targeted Metabolomic Analysis of a Mucopolysaccharidosis IIIB Mouse Model Reveals an Imbalance of Branched-Chain Amino Acid and Fatty Acid Metabolism.Other primary literatureHuman & animalActiveInternational journal of molecular sciences2020
De Pasquale V, Caterino M, Costanzo M, et al.
Low Serum Branched-Chain Amino Acid and Insulin-Like Growth Factor-1 Levels Are Associated with Sarcopenia and Slow Gait Speed in Patients with Liver Cirrhosis.Other primary literatureUnknownActiveJournal of clinical medicine2020
Saeki C, Kanai T, Nakano M, et al.
Effects of Branched-Chain Amino Acid (BCAA) Supplementation on the Progression of Advanced Liver Disease: A Korean Nationwide, Multicenter, Prospective, Observational, Cohort Study.Observational studyHumanActiveNutrients2020
Park JG, Tak WY, Park SY, et al.
Effect of branched chain amino acid supplementation on dialysis adequacy and nutritional parameters in hemodialysis patients.Other primary literatureHumanActiveSaudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia2020
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Plasma BCAA concentrations during exercise of varied intensities in young healthy men-the impact of endurance training.Other primary literatureUnknownActivePeerJ2020
Gawedzka A, Grandys M, Duda K, et al.
Different regulation of branched-chain amino acid on food intake by TOR signaling in Chinese perch (Siniperca chuatsi)Other primary literatureUnknownUnknownAquaculture.2020
Chen K, Zhang Z, Li J, et al.
Expanding the genetic and phenotypic spectrum of branched-chain amino acid transferase 2 deficiency.Other primary literatureHumanActiveJournal of inherited metabolic disease2019
Knerr I, Colombo R, Urquhart J, et al.
Preoperative Oral Branched-Chain Amino Acid Supplementation Suppresses Intraoperative and Postoperative Blood Lactate Levels in Patients Undergoing Major Hepatectomy.Other primary literatureHumanActiveJPEN. Journal of parenteral and enteral nutrition2019
Nanno Y, Toyama H, Terai S, et al.
High Branched-Chain Amino Acid Concentrations Are Found in Preterm Baboons Receiving Intravenous Amino Acid Solutions and Mimic Alterations Found in Preterm Infants.Other primary literatureHuman & animalActiveJPEN. Journal of parenteral and enteral nutrition2019
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Lower Circulating Branched-Chain Amino Acid Concentrations Among Vegetarians are Associated with Changes in Gut Microbial Composition and Function.Other primary literatureHumanActiveMolecular nutrition & food research2019
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Enhanced cerebral branched-chain amino acid metabolism in R6/2 mouse model of Huntington's disease.Other primary literatureAnimalActiveCellular and molecular life sciences : CMLS2019
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Overexpression of branched-chain amino acid aminotransferases rescues the growth defects of cells lacking the Barth syndrome-related gene TAZ1.Other primary literatureHumanActiveJournal of molecular medicine (Berlin, Germany)2019
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Biochemical and structural characterization of a highly active branched-chain amino acid aminotransferase from Pseudomonas sp. for efficient biosynthesis of chiral amino acids.Other primary literatureUnknownActiveApplied microbiology and biotechnology2019
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The overexpression of cucumber (Cucumis sativus L.) genes that encode the branched-chain amino acid transferase modulate flowering time in Arabidopsis thaliana.Other primary literatureUnknownActivePlant cell reports2019
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Branched-chain amino acid catabolism of Thermoanaerobacter strain AK85 and the influence of culture conditions on branched-chain alcohol formation.Other primary literatureUnknownActiveAmino acids2019
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GC-MS metabolic profiling reveals fructose-2,6-bisphosphate regulates branched chain amino acid metabolism in the heart during fasting.Other primary literatureAnimalActiveMetabolomics : Official journal of the Metabolomic Society2019
Batushansky A, Matsuzaki S, Newhardt MF, et al.
FgIlv3a is crucial in branched-chain amino acid biosynthesis, vegetative differentiation, and virulence in Fusarium graminearum.Other primary literatureUnknownActiveJournal of microbiology (Seoul, Korea)2019
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Aqueous Humor Analysis Identifies Higher Branched Chain Amino Acid Metabolism as a Marker for Human Leukocyte Antigen-B27 Acute Anterior Uveitis and Disease Activity.Other primary literatureHumanActiveAmerican journal of ophthalmology2019
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Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase Inhibitors.Other primary literatureHumanActiveCell reports2019
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Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression.Other primary literatureHuman & animalActiveCell metabolism2019
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Decreased plasma l-arginine levels in organic acidurias (MMA and PA) and decreased plasma branched-chain amino acid levels in urea cycle disorders as a potential cause of growth retardation: Options for treatment.Other primary literatureHumanActiveMolecular genetics and metabolism2019
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Metabolic analysis reveals evidence for branched chain amino acid catabolism crosstalk and the potential for improved treatment of organic acidurias.Other primary literatureHumanActiveMolecular genetics and metabolism2019
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OLIVe: A Genetically Encoded Fluorescent Biosensor for Quantitative Imaging of Branched-Chain Amino Acid Levels inside Single Living Cells.Other primary literatureHumanActiveACS sensors2019
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Newly characterized mitochondrial BCAA transporter.Other primary literatureHumanActiveNature reviews. Endocrinology2019
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BCAA catabolism in brown fat controls energy homeostasis through SLC25A44.Other primary literatureHuman & animalActiveNature2019
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The active site of the Mycobacterium tuberculosis branched-chain amino acid biosynthesis enzyme dihydroxyacid dehydratase contains a 2Fe-2S cluster.Other primary literatureUnknownActiveThe Journal of biological chemistry2019
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Impact of Branched-Chain Amino Acid Granule Therapy in Patients with Hepatocellular Carcinoma Who Have Normal Albumin Levels and Low Branched-Chain Amino Acid to Tyrosine Ratios.Other primary literatureHumanActiveNutrition and cancer2019
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Malignant manipulaTORs of metabolism: suppressing BCAA catabolism to enhance mTORC1 activity.Other primary literatureUnknownActiveMolecular & cellular oncology2019
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Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: a double-blind, randomized trial.Randomized controlled trialHumanActiveThe American journal of clinical nutrition2019
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Iron-sulfur protein NFU2 is required for branched-chain amino acid synthesis in Arabidopsis roots.Other primary literatureUnknownActiveJournal of experimental botany2019
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Role of branched-chain amino acid-catabolizing enzymes in intertissue signaling, metabolic remodeling, and energy homeostasis.ReviewHuman & animalActiveFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019
Biswas D, Duffley L, Pulinilkunnil T
Effects of Branched-Chain Amino Acid Supplementation on Spontaneous Seizures and Neuronal Viability in a Model of Mesial Temporal Lobe Epilepsy.Other primary literatureAnimalActiveJournal of neurosurgical anesthesiology2019
Gruenbaum SE, Dhaher R, Rapuano A, et al.
Can L-carnitine supplementation and exercise improve muscle complications in patients with liver cirrhosis who receive branched-chain amino acid supplementation?Other primary literatureHumanActiveEuropean journal of gastroenterology & hepatology2019
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Branched-Chain Amino Acid Catabolism Impacts Triacylglycerol Homeostasis in Chlamydomonas reinhardtii.Other primary literatureUnknownActivePlant physiology2019
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Effects of branched-chain amino acid supplementation and/or aerobic exercise on mouse sperm quality and testosterone production.Other primary literatureAnimalActiveAndrologia2019
Bahadorani M, Tavalaee M, Abedpoor N, et al.
The Effects of Leucine-Enriched Branched-Chain Amino Acid Supplementation on Recovery After High-Intensity Resistance Exercise.Randomized controlled trialHumanActiveInternational journal of sports physiology and performance2019
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Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation.Other primary literatureHuman & animalActiveCancer discovery2019
Gu Z, Liu Y, Cai F, et al.
Late-Evening Carbohydrate and Branched-Chain Amino Acid Snacks Improve the Nutritional Status of Patients Undergoing Hepatectomy Based on Bioelectrical Impedance Analysis of Body Composition.Other primary literatureUnknownActiveGastrointestinal tumors2019
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Therapeutic Effect of Targeting Branched-Chain Amino Acid Catabolic Flux in Pressure-Overload Induced Heart Failure.Other primary literatureAnimalActiveJournal of the American Heart Association2019
Chen M, Gao C, Yu J, et al.
Impaired branched chain amino acid oxidation contributes to cardiac insulin resistance in heart failure.Other primary literatureHuman & animalActiveCardiovascular diabetology2019
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Fine-scale haplotype mapping of MUT, AACS, SLC6A15 and PRKCA genes indicates association with insulin resistance of metabolic syndrome and relationship with branched chain amino acid metabolism or regulation.Other primary literatureHumanActivePloS one2019
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Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance.Other primary literatureHuman & animalActiveDiabetes2019
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[The efficiency of branched chain aminoacids (BCAA) in the nutrition of combat sport athletes].Other primary literatureHumanActiveVoprosy pitaniia2019
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Changes in tissue abundance and activity of enzymes related to branched-chain amino acid catabolism in dairy cows during early lactation.Other primary literatureAnimalActiveJournal of dairy science2019
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Effect of rumen-protected branched-chain amino acid supplementation on production- and energy-related metabolites during the first 35 days in milk in Holstein dairy cows.Other primary literatureAnimalActiveJournal of dairy science2019
Leal Yepes FA, Mann S, Overton TR, et al.
Isolated branched-chain amino acid intake and muscle protein synthesis in humans: a biochemical review.ReviewHumanActiveEinstein (Sao Paulo, Brazil)2019
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Thermostable Branched-Chain Amino Acid Transaminases From the Archaea Geoglobus acetivorans and Archaeoglobus fulgidus: Biochemical and Structural Characterization.Other primary literatureUnknownCorrectedFrontiers in bioengineering and biotechnology2019
Isupov MN, Boyko KM, Sutter JM, et al.
In vitro Activity and Heteroresistance of Omadacycline Against Clinical Staphylococcus aureus Isolates From China Reveal the Impact of Omadacycline Susceptibility by Branched-Chain Amino Acid Transport System II Carrier Protein, Na/Pi Cotransporter Family Protein, and Fibronectin-Binding Protein.Other primary literatureUnknownActiveFrontiers in microbiology2019
Bai B, Lin Z, Pu Z, et al.
BCAA Catabolic Defect Alters Glucose Metabolism in Lean Mice.Other primary literatureUnknownActiveFrontiers in physiology2019
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Associations Between Dietary Protein Sources, Plasma BCAA and Short-Chain Acylcarnitine Levels in Adults.Other primary literatureHumanActiveNutrients2019
Rousseau M, Guénard F, Garneau V, et al.
Late-Evening Snack with Branched-Chain Amino Acid-Enriched Nutrients Does Not Always Inhibit Overt Diabetes in Patients with Cirrhosis: A Pilot Study.Other primary literatureHumanActiveNutrients2019
Nakanishi K, Namisaki T, Mashitani T, et al.
Nutritional deficiency dermatitis related to branched-chain amino acid restriction in a child with maple syrup urine disease.Other primary literatureHumanActiveDermatology online journal2019
Campuzano-García AE, Castanedo-Cázares JP
Effect of exercise therapy combined with branched-chain amino acid supplementation on muscle strength in elderly women after total hip arthroplasty: a randomized controlled trial.Randomized controlled trialHumanActiveAsia Pacific journal of clinical nutrition2019
Ikeda T, Matsunaga Y, Kanbara M, et al.
Natural variation in C. elegans arsenic toxicity is explained by differences in branched chain amino acid metabolism.Other primary literatureHuman & animalActiveeLife2019
Zdraljevic S, Fox BW, Strand C, et al.
The pattern of plasma BCAA concentration and liver Bckdha gene expression in GK rats during T2D progression.Other primary literatureUnknownActiveAnimal models and experimental medicine2018
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BCAA Metabolism and Insulin Sensitivity - Dysregulated by Metabolic Status?ReviewHuman & animalActiveMolecular nutrition & food research2018
Gannon NP, Schnuck JK, Vaughan RA
Short- and long-term effects of leucine and branched-chain amino acid supplementation of a protein- and energy-reduced diet on muscle protein metabolism in neonatal pigs.Other primary literatureAnimalActiveAmino acids2018
Manjarín R, Columbus DA, Solis J, et al.
Production of pikromycin using branched chain amino acid catabolism in Streptomyces venezuelae ATCC 15439.Other primary literatureUnknownActiveJournal of industrial microbiology & biotechnology2018
Yi JS, Kim M, Kim EJ, et al.
Insulin and branched-chain amino acid depletion during mouse preimplantation embryo culture programmes body weight gain and raised blood pressure during early postnatal life.Other primary literatureAnimalActiveBiochimica et biophysica acta. Molecular basis of disease2018
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miR-124-3p affects the formation of intramuscular fat through alterations in branched chain amino acid consumption in sheep.Other primary literatureAnimalActiveBiochemical and biophysical research communications2018
Pan Y, Jing J, Qiao L, et al.
Effects of branched chain amino acid supplementation on patient care outcomes in adults and children with liver cirrhosis: A systematic review.Systematic reviewHumanActiveClinical nutrition ESPEN2018
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The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase.Other primary literatureHuman & animalActiveCell metabolism2018
White PJ, McGarrah RW, Grimsrud PA, et al.
Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice.Other primary literatureAnimalActiveEBioMedicine2018
Walter LM, Deguise MO, Meijboom KE, et al.
Branched-chain amino acid depletion conditions bone marrow for hematopoietic stem cell transplantation avoiding amino acid imbalance-associated toxicity.Other primary literatureHuman & animalActiveExperimental hematology2018
Wilkinson AC, Morita M, Nakauchi H, et al.
Identification of branched-chain amino acid aminotransferases active towards (R)-(+)-1-phenylethylamine among PLP fold type IV transaminases.Other primary literatureUnknownActiveJournal of biotechnology2018
Bezsudnova EY, Dibrova DV, Nikolaeva AY, et al.
Increased branched-chain amino acid levels are associated with long-term adverse cardiovascular events in patients with STEMI and acute heart failure.Other primary literatureHumanActiveLife sciences2018
Du X, Li Y, Wang Y, et al.
PPARγ is a major regulator of branched-chain amino acid blood levels and catabolism in white and brown adipose tissues.Other primary literatureAnimalActiveMetabolism: clinical and experimental2018
Blanchard PG, Moreira RJ, Castro É, et al.
Time-course changes in circulating branched-chain amino acid levels and metabolism in obese Yucatan minipig.Other primary literatureAnimalActiveNutrition (Burbank, Los Angeles County, Calif.)2018
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Optimal branched-chain amino acid ratio improves cell proliferation and protein metabolism of porcine enterocytesin in vivo and in vitro.Other primary literatureAnimalActiveNutrition (Burbank, Los Angeles County, Calif.)2018
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Krüppel-like factor 15: Regulator of BCAA metabolism and circadian protein rhythmicity.ReviewHuman & animalActivePharmacological research2018
Fan L, Hsieh PN, Sweet DR, et al.
Enhancement of precursor amino acid supplies for improving bacitracin production by activation of branched chain amino acid transporter BrnQ and deletion of its regulator gene lrp in Bacillus licheniformis.Other primary literatureUnknownActiveSynthetic and systems biotechnology2018
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A case of Kounis syndrome associated with branched-chain amino acid supplementation in a 17-year-old boy.Other primary literatureHumanActiveCardiology in the young2018
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Gabapentin Can Suppress Cell Proliferation Independent of the Cytosolic Branched-Chain Amino Acid Transferase 1 (BCAT1).Other primary literatureHumanActiveBiochemistry2018
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Glucose promotes cell growth by suppressing branched-chain amino acid degradation.Other primary literatureHuman & animalActiveNature communications2018
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Relationships between circulating branched chain amino acid concentrations and risk of adverse cardiovascular events in patients with STEMI treated with PCI.Other primary literatureHumanActiveScientific reports2018
Du X, You H, Li Y, et al.
Defect of branched-chain amino acid metabolism promotes the development of Alzheimer's disease by targeting the mTOR signaling.Other primary literatureHuman & animalActiveBioscience reports2018
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Increased Levels of Branched-Chain Amino Acid Associated With Increased Risk of Pancreatic Cancer in a Prospective Case-Control Study of a Large Cohort.Other primary literatureHumanActiveGastroenterology2018
Katagiri R, Goto A, Nakagawa T, et al.
Branched-chain amino acid (BCAA) supplementation enhances adaptability to exercise training of mice with a muscle-specific defect in the control of BCAA catabolism.Other primary literatureUnknownActiveBioscience, biotechnology, and biochemistry2018
Xu M, Kitaura Y, Shindo D, et al.
Memory Deficit in an Object Location Task after Mild Traumatic Brain Injury Is Associated with Impaired Early Object Exploration and Both Are Restored by Branched Chain Amino Acid Dietary Therapy.Other primary literatureAnimalActiveJournal of neurotrauma2018
Paterno R, Metheny H, Cohen AS
Divergent Induction of Branched-Chain Aminotransferases and Phosphorylation of Branched Chain Keto-Acid Dehydrogenase Is a Potential Mechanism Coupling Branched-Chain Keto-Acid-Mediated-Astrocyte Activation to Branched-Chain Amino Acid Depletion-Mediated Cognitive Deficit after Traumatic Brain Injury.Other primary literatureAnimalActiveJournal of neurotrauma2018
Xing G, Ren M, Verma A
Alterations in branched-chain amino acid kinetics in nonobese but insulin-resistant Asian men.Other primary literatureHumanActiveThe American journal of clinical nutrition2018
Tan HC, Hsu JW, Khoo CM, et al.
Influence of excess branched-chain amino acid uptake by Streptococcus mutans in human host cells.Other primary literatureHumanActiveFEMS microbiology letters2018
Arimoto T, Yambe R, Morisaki H, et al.
Post-ruminal branched-chain amino acid supplementation and intravenous lipopolysaccharide infusion alter blood metabolites, rumen fermentation, and nitrogen balance of beef steers.Other primary literatureAnimalActiveJournal of animal science2018
Löest CA, Gilliam GG, Waggoner JW, et al.
Altered branched chain amino acid metabolism: toward a unifying cardiometabolic hypothesis.ReviewHuman & animalActiveCurrent opinion in cardiology2018
Tobias DK, Mora S, Verma S, et al.
Emerging perspectives on branched-chain amino acid metabolism during adipocyte differentiation.ReviewHuman & animalActiveCurrent opinion in clinical nutrition and metabolic care2018
Salinas-Rubio D, Tovar AR, Noriega LG
Branched-chain amino acid metabolism in cancer.ReviewHuman & animalActiveCurrent opinion in clinical nutrition and metabolic care2018
Ananieva EA, Wilkinson AC
Muscle wasting and branched-chain amino acid, alpha-ketoglutarate, and ATP depletion in a rat model of liver cirrhosis.Other primary literatureAnimalActiveInternational journal of experimental pathology2018
Holeček M, Vodeničarovová M
Branched-chain amino acid ratios in low-protein diets regulate the free amino acid profile and the expression of hepatic fatty acid metabolism-related genes in growing pigs.Randomized controlled trialAnimalActiveJournal of animal physiology and animal nutrition2018
Duan YH, Li FN, Wen CY, et al.
Metabolic reconstructions identify plant 3-methylglutaconyl-CoA hydratase that is crucial for branched-chain amino acid catabolism in mitochondria.Other primary literatureUnknownActiveThe Plant journal : for cell and molecular biology2018
Latimer S, Li Y, Nguyen TTH, et al.
Reducing branched-chain amino acid intake to reverse metabolic complications in obesity and type 2 diabetes.Other primary literatureHumanActiveThe Journal of physiology2018
Yadao DR, MacKenzie S, Bergdahl A
PccD Regulates Branched-Chain Amino Acid Degradation and Exerts a Negative Effect on Erythromycin Production in Saccharopolyspora erythraea.Other primary literatureUnknownActiveApplied and environmental microbiology2018
Xu Z, Liu Y, Ye BC
Branching Out: Alterations in Bacterial Physiology and Virulence Due to Branched-Chain Amino Acid Deprivation.ReviewUnknownActivemBio2018
Kaiser JC, Heinrichs DE
Effects of long-term exposures to low iron and branched-chain amino acid containing diets on aging skeletal muscle of Fisher 344 × Brown Norway rats.Other primary literatureAnimalActiveApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2018
Kim Y, Men SS, Liang C, et al.
Effects of carbohydrate and branched-chain amino acid beverage ingestion during acute upper body resistance exercise on performance and postexercise hormone response.Randomized controlled trialHumanActiveApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2018
Smith JW, Krings BM, Shepherd BD, et al.
Effect of exercise therapy combined with branched-chain amino acid supplementation on muscle strengthening in persons with osteoarthritis.Other primary literatureUnknownActiveHong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao2018
Ikeda T, Jinno T, Masuda T, et al.
Cardiac branched-chain amino acid oxidation is reduced during insulin resistance in the heart.Other primary literatureAnimalActiveAmerican journal of physiology. Endocrinology and metabolism2018
Fillmore N, Wagg CS, Zhang L, et al.
Altered Redox Homeostasis in Branched-Chain Amino Acid Disorders, Organic Acidurias, and Homocystinuria.ReviewHuman & animalActiveOxidative medicine and cellular longevity2018
Richard E, Gallego-Villar L, Rivera-Barahona A, et al.
Repression of branched-chain amino acid synthesis in Staphylococcus aureus is mediated by isoleucine via CodY, and by a leucine-rich attenuator peptide.Other primary literatureUnknownActivePLoS genetics2018
Kaiser JC, King AN, Grigg JC, et al.
Valine biosynthesis in Saccharomyces cerevisiae is regulated by the mitochondrial branched-chain amino acid aminotransferase Bat1.Other primary literatureUnknownActiveMicrobial cell (Graz, Austria)2018
Takpho N, Watanabe D, Takagi H
Effect of BCAA supplement timing on exercise-induced muscle soreness and damage: a pilot placebo-controlled double-blind study.Randomized controlled trialHumanActiveThe Journal of sports medicine and physical fitness2018
Ra SG, Miyazaki T, Kojima R, et al.
Maintenance of plasma branched-chain amino acid concentrations during glucose infusion directs essential amino acids to extra-mammary tissues in lactating dairy cows.Other primary literatureAnimalActiveJournal of dairy science2018
Curtis RV, Kim JJM, Doelman J, et al.
Impact of Branched-Chain Amino Acid Catabolism on Fatty Acid and Alkene Biosynthesis in Micrococcus luteus.Other primary literatureUnknownActiveFrontiers in microbiology2018
Surger MJ, Angelov A, Stier P, et al.
The Defense-Related Isoleucic Acid Differentially Accumulates in Arabidopsis Among Branched-Chain Amino Acid-Related 2-Hydroxy Carboxylic Acids.Other primary literatureUnknownCorrectedFrontiers in plant science2018
Maksym RP, Ghirardo A, Zhang W, et al.
Dietary Pattern and Plasma BCAA-Variations in Healthy Men and Women-Results from the KarMeN Study.Other primary literatureHumanActiveNutrients2018
Merz B, Frommherz L, Rist MJ, et al.
Effect of Branched-Chain Amino Acid Supplementation on Recovery Following Acute Eccentric Exercise.Randomized controlled trialHumanActiveNutrients2018
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Branched-Chain Amino Acid Database Integrated in MEDIPAD Software as a Tool for Nutritional Investigation of Mediterranean Populations.Other primary literatureHumanActiveNutrients2018
Haydar S, Paillot T, Fagot C, et al.
Effect of branched-chain amino acid supplementation on insulin resistance and quality of life in chronic hepatitis C patients.Other primary literatureUnknownActiveBiomedical reports2018
Ocaña-Mondragón A, Mata-Marín JA, Uriarte-López M, et al.
Effects of dietary valine:lysine ratio on the performance, amino acid composition of tissues and mRNA expression of genes involved in branched-chain amino acid metabolism of weaned piglets.Other primary literatureUnknownActiveAsian-Australasian Journal of Animal Sciences2018
Xu YT, Ma XK, Wang CL, et al.
BCAT1 promotes proliferation of endometrial cancer cells through reprogrammed BCAA metabolism.Other primary literatureUnknownActiveInternational journal of clinical and experimental pathology2018
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Genetic evidence of a causal effect of insulin resistance on branched-chain amino acid levels.Other primary literatureHumanActiveDiabetologia2017
Mahendran Y, Jonsson A, Have CT, et al.
Oral branched-chain amino acid granules improve structure and function of human serum albumin in cirrhotic patients.Other primary literatureHumanActiveJournal of gastroenterology2017
Setoyama H, Tanaka M, Nagumo K, et al.
Enzymes involved in branched-chain amino acid metabolism in humans.ReviewHumanActiveAmino acids2017
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Anti-inflammatory and anti-genotoxic activity of branched chain amino acids (BCAA) in lipopolysaccharide (LPS) stimulated RAW 264.7 macrophages.Other primary literatureUnknownActiveFood science and biotechnology2017
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Effect of decreased BCAA synthesis through disruption of ilvC gene on the virulence of Streptococcus pneumoniae.Other primary literatureAnimalActiveArchives of pharmacal research2017
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Intact Protein Analysis at 21 Tesla and X-Ray Crystallography Define Structural Differences in Single Amino Acid Variants of Human Mitochondrial Branched-Chain Amino Acid Aminotransferase 2 (BCAT2).Other primary literatureHumanActiveJournal of the American Society for Mass Spectrometry2017
Anderson LC, Håkansson M, Walse B, et al.
Branched-chain amino acid transaminase 1 (BCAT1) promotes the growth of breast cancer cells through improving mTOR-mediated mitochondrial biogenesis and function.Other primary literatureHumanActiveBiochemical and biophysical research communications2017
Zhang L, Han J
Defective Branched-Chain Amino Acid Catabolism Disrupts Glucose Metabolism and Sensitizes the Heart to Ischemia-Reperfusion Injury.Other primary literatureAnimalActiveCell metabolism2017
Li T, Zhang Z, Kolwicz SC Jr, et al.
BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer.Other primary literatureHuman & animalActiveEBioMedicine2017
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A Novel highly thermostable branched-chain amino acid aminotransferase from the crenarchaeon Vulcanisaeta moutnovskia.Other primary literatureUnknownActiveEnzyme and microbial technology2017
Stekhanova TN, Rakitin AL, Mardanov AV, et al.
Liver BCATm transgenic mouse model reveals the important role of the liver in maintaining BCAA homeostasis.Other primary literatureAnimalActiveThe Journal of nutritional biochemistry2017
Ananieva EA, Van Horn CG, Jones MR, et al.
Branched-chain amino acid catabolism rather than amino acids plasma concentrations is associated with diet-induced changes in insulin resistance in overweight to obese individuals.Randomized controlled trialHumanActiveNutrition, metabolism, and cardiovascular diseases : NMCD2017
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Effects of branched-chain amino acid supplementation after radiofrequency ablation for hepatocellular carcinoma: A randomized trial.Randomized controlled trialHumanActiveNutrition (Burbank, Los Angeles County, Calif.)2017
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Effect of branched-chain amino acid ratio on the proliferation, differentiation, and expression levels of key regulators involved in protein metabolism of myocytes.Other primary literatureAnimalActiveNutrition (Burbank, Los Angeles County, Calif.)2017
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Branched-chain amino acid supplementation in treatment of liver cirrhosis: Updated views on how to attenuate their harmful effects on cataplerosis and ammonia formation.ReviewHumanActiveNutrition (Burbank, Los Angeles County, Calif.)2017
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Uncovering the role of branched-chain amino acid transaminases in Saccharomyces cerevisiae isobutanol biosynthesis.Other primary literatureUnknownCorrectedMetabolic engineering2017
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Branched-chain amino acid, meat intake and risk of type 2 diabetes in the Women's Health Initiative.Other primary literatureHumanActiveThe British journal of nutrition2017
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Bacterial Branched-Chain Amino Acid Biosynthesis: Structures, Mechanisms, and Drugability.ReviewUnknownActiveBiochemistry2017
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Effects of Low-Protein Diets Supplemented with Branched-Chain Amino Acid on Lipid Metabolism in White Adipose Tissue of Piglets.Other primary literatureAnimalActiveJournal of agricultural and food chemistry2017
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Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia.Other primary literatureHuman & animalActiveNature2017
Hattori A, Tsunoda M, Konuma T, et al.
The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ERα-negative breast cancer.Other primary literatureHuman & animalActiveOncogene2017
Thewes V, Simon R, Hlevnjak M, et al.
Transcriptional hallmarks of cancer cell lines reveal an emerging role of branched chain amino acid catabolism.Other primary literatureHumanActiveScientific reports2017
Antanavičiūtė I, Mikalayeva V, Ceslevičienė I, et al.
Impaired branched-chain amino acid metabolism may underlie the nonalcoholic fatty liver disease-like pathology of neonatal testosterone-treated female rats.Other primary literatureHuman & animalActiveScientific reports2017
Anzai Á, Marcondes RR, Gonçalves TH, et al.
Structure of the Branched-chain Amino Acid and GTP-sensing Global Regulator, CodY, from <i>Bacillus subtilis</i>.Other primary literatureUnknownActiveThe Journal of biological chemistry2017
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Effect of branched-chain amino acid supplements on muscle strength and muscle mass in patients with liver cirrhosis.Other primary literatureHumanActiveEuropean journal of gastroenterology & hepatology2017
Uojima H, Sakurai S, Hidaka H, et al.
Efficacy of branched-chain amino acid supplementation and walking exercise for preventing sarcopenia in patients with liver cirrhosis.Other primary literatureHumanActiveEuropean journal of gastroenterology & hepatology2017
Hiraoka A, Michitaka K, Kiguchi D, et al.
A Regulatory Hierarchy of the Arabidopsis Branched-Chain Amino Acid Metabolic Network.Other primary literatureUnknownActiveThe Plant cell2017
Xing A, Last RL
Burkholderia cenocepacia K56-2 trimeric autotransporter adhesin BcaA binds TNFR1 and contributes to induce airway inflammation.Other primary literatureHumanActiveCellular microbiology2017
Mil-Homens D, Pinto SN, Matos RG, et al.
"Weariness" and "unpleasantness" reduce adherence to branched-chain amino acid granules among Japanese patients with liver cirrhosis: results of a single-center cross-sectional survey.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2017
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Effects of home-based exercise and branched-chain amino acid supplementation on aerobic capacity and glycemic control in patients with cirrhosis.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2017
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Acute effects of phenylbutyrate on glutamine, branched-chain amino acid and protein metabolism in skeletal muscles of rats.Other primary literatureAnimalActiveInternational journal of experimental pathology2017
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A randomized controlled trial: branched-chain amino acid levels and glucose metabolism in patients with obesity and sleep apnea.Randomized controlled trialHumanActiveJournal of sleep research2017
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Properties of Bacterial and Archaeal Branched-Chain Amino Acid Aminotransferases.ReviewUnknownActiveBiochemistry. Biokhimiia2017
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The effects of acute branched-chain amino acid supplementation on recovery from a single bout of hypertrophy exercise in resistance-trained athletes.Randomized controlled trialHumanActiveApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2017
Waldron M, Whelan K, Jeffries O, et al.
Anesthesia and bariatric surgery gut preparation alter plasma acylcarnitines reflective of mitochondrial fat and branched-chain amino acid oxidation.Other primary literatureHumanActiveAmerican journal of physiology. Endocrinology and metabolism2017
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Effect of Oral Branched-Chain Amino Acid Supplementation on Postoperative Blood Lactate Levels in Patients Undergoing Pancreatoduodenectomy.Other primary literatureUnknownActiveJPEN. Journal of parenteral and enteral nutrition2017
Nanno Y, Toyama H, Terai S, et al.
Acetolactate synthase regulatory subunits play divergent and overlapping roles in branched-chain amino acid synthesis and Arabidopsis development.Other primary literatureUnknownActiveBMC plant biology2017
Dezfulian MH, Dezfulian MH, Foreman C, et al.
An exploratory study on the efficacy and safety of a BCAA preparation used in combination with cardiac rehabilitation for patients with chronic heart failure.Randomized controlled trialHumanActiveBMC cardiovascular disorders2017
Takata M, Amiya E, Watanabe M, et al.
Branched-chain amino acid supplementation restores reduced insulinotropic activity of a low-protein diet through the vagus nerve in rats.Other primary literatureUnknownActiveNutrition & metabolism2017
Horiuchi M, Takeda T, Takanashi H, et al.
Elevated α-Hydroxybutyrate and Branched-Chain Amino Acid Levels Predict Deterioration of Glycemic Control in Adolescents.Other primary literatureHumanActiveThe Journal of clinical endocrinology and metabolism2017
Tricò D, Prinsen H, Giannini C, et al.
Nutritional modulation of mouse and human liver bud growth through a branched-chain amino acid metabolism.Other primary literatureHuman & animalActiveDevelopment (Cambridge, England)2017
Koike H, Zhang RR, Ueno Y, et al.
Endurance performance and energy metabolism during exercise in mice with a muscle-specific defect in the control of branched-chain amino acid catabolism.Other primary literatureAnimalActivePloS one2017
Xu M, Kitaura Y, Ishikawa T, et al.
Evaluation of the branched-chain amino acid-to-tyrosine ratio prior to treatment as a prognostic predictor in patients with liver cirrhosis.Other primary literatureUnknownActiveOncotarget2017
Ishikawa T, Imai M, Ko M, et al.
Alteration of muscle fiber characteristics and the AMPK-SIRT1-PGC-1α axis in skeletal muscle of growing pigs fed low-protein diets with varying branched-chain amino acid ratios.Other primary literatureUnknownActiveOncotarget2017
Duan Y, Li F, Wang W, et al.
Branched-Chain Amino Acid Ingestion Stimulates Muscle Myofibrillar Protein Synthesis following Resistance Exercise in Humans.Other primary literatureUnknownActiveFrontiers in physiology2017
Jackman SR, Witard OC, Philp A, et al.
Branched-Chain Amino Acid Negatively Regulates KLF15 Expression via PI3K-AKT Pathway.Other primary literatureUnknownActiveFrontiers in physiology2017
Liu Y, Dong W, Shao J, et al.
The Effects of Herbicides Targeting Aromatic and Branched Chain Amino Acid Biosynthesis Support the Presence of Functional Pathways in Broomrape.Other primary literatureUnknownActiveFrontiers in plant science2017
Dor E, Galili S, Smirnov E, et al.
Effects of EPSPS Copy Number Variation (CNV) and Glyphosate Application on the Aromatic and Branched Chain Amino Acid Synthesis Pathways in Amaranthus palmeri.Other primary literatureUnknownActiveFrontiers in plant science2017
Fernández-Escalada M, Zulet-González A, Gil-Monreal M, et al.
Dietary BCAA Intake Is Associated with Demographic, Socioeconomic and Lifestyle Factors in Residents of São Paulo, Brazil.Other primary literatureHuman & animalActiveNutrients2017
Pallottini AC, Sales CH, Vieira DADS, et al.
Leucine Supplementation Differently Modulates Branched-Chain Amino Acid Catabolism, Mitochondrial Function and Metabolic Profiles at the Different Stage of Insulin Resistance in Rats on High-Fat Diet.Other primary literatureAnimalActiveNutrients2017
Liu R, Li H, Fan W, et al.
A Branched-Chain Amino Acid-Related Metabolic Signature Characterizes Obese Adolescents with Non-Alcoholic Fatty Liver Disease.Other primary literatureHumanActiveNutrients2017
Goffredo M, Santoro N, Tricò D, et al.
Wheat-bran autolytic peptides containing a branched-chain amino acid attenuate non-alcoholic steatohepatitis via the suppression of oxidative stress and the upregulation of AMPK/ACC in high-fat diet-fed mice.Other primary literatureAnimalActiveInternational journal of molecular medicine2017
Kawaguchi T, Ueno T, Nogata Y, et al.
mTORC1 is involved in the regulation of branched-chain amino acid catabolism in mouse heart.Other primary literatureUnknownActiveFEBS open bio2016
Zhen H, Kitaura Y, Kadota Y, et al.
BCAA Metabolism and NH3 Homeostasis.Other primary literatureHuman & animalActiveAdvances in neurobiology2016
Conway ME, Hutson SM
Ten weeks of branched-chain amino acid supplementation improves select performance and immunological variables in trained cyclists.Other primary literatureHumanCorrectedAmino acids2016
Kephart WC, Wachs TD, Thompson RM, et al.
Identification and characterization of novel anticoagulant peptide with thrombolytic effect and nutrient oligopeptides with high branched chain amino acid from Whitmania pigra protein.Other primary literatureHuman & animalActiveAmino acids2016
Ren Y, Yang Y, Wu W, et al.
Metabolic shifts and structural changes in the gut microbiota upon branched-chain amino acid supplementation in middle-aged mice.Other primary literatureHuman & animalActiveAmino acids2016
Yang Z, Huang S, Zou D, et al.
First structure of archaeal branched-chain amino acid aminotransferase from Thermoproteus uzoniensis specific for L-amino acids and R-amines.Other primary literatureUnknownActiveExtremophiles : life under extreme conditions2016
Boyko KM, Stekhanova TN, Nikolaeva AY, et al.
The Effects of Sleeve Gastrectomy and Gastric Bypass on Branched-Chain Amino Acid Metabolism 1 Year After Bariatric Surgery.Other primary literatureHumanActiveObesity surgery2016
Tan HC, Khoo CM, Tan MZ, et al.
Metabolic switch during adipogenesis: From branched chain amino acid catabolism to lipid synthesis.Other primary literatureAnimalActiveArchives of biochemistry and biophysics2016
Halama A, Horsch M, Kastenmüller G, et al.
Experimental and computational studies on the unusual substrate specificity of branched-chain amino acid aminotransferase from Thermoproteus uzoniensis.Other primary literatureUnknownActiveArchives of biochemistry and biophysics2016
Bezsudnova EY, Stekhanova TN, Suplatov DA, et al.
Branched chain amino acid metabolic reprogramming in heart failure.ReviewHuman & animalActiveBiochimica et biophysica acta2016
Sun H, Wang Y
Changes in body composition in heart failure patients after a resistance exercise program and branched chain amino acid supplementation.Randomized controlled trialHumanActiveClinical nutrition (Edinburgh, Scotland)2016
Pineda-Juárez JA, Sánchez-Ortiz NA, Castillo-Martínez L, et al.
Associations between branched chain amino acid intake and biomarkers of adiposity and cardiometabolic health independent of genetic factors: A twin study.Other primary literatureHumanActiveInternational journal of cardiology2016
Jennings A, MacGregor A, Pallister T, et al.
Increased susceptibility to metabolic dysregulation in a mouse model of Alzheimer's disease is associated with impaired hypothalamic insulin signaling and elevated BCAA levels.Other primary literatureHuman & animalActiveAlzheimer's & dementia : the journal of the Alzheimer's Association2016
Ruiz HH, Chi T, Shin AC, et al.
Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export.Other primary literatureUnknownActiveMolecular metabolism2016
White PJ, Lapworth AL, An J, et al.
Defects in muscle branched-chain amino acid oxidation contribute to impaired lipid metabolism.Other primary literatureUnknownActiveMolecular metabolism2016
Lerin C, Goldfine AB, Boes T, et al.
High-Speed Microdialysis-Capillary Electrophoresis Assays for Measuring Branched Chain Amino Acid Uptake in 3T3-L1 cells.Other primary literatureAnimalActiveAnalytical chemistry2016
Harstad RK, Bowser MT
Reanalysis of mGWAS results and in vitro validation show that lactate dehydrogenase interacts with branched-chain amino acid metabolism.Other primary literatureHumanActiveEuropean journal of human genetics : EJHG2016
Heemskerk MM, van Harmelen VJ, van Dijk KW, et al.
Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis.Other primary literatureHuman & animalActiveNature chemical biology2016
Green CR, Wallace M, Divakaruni AS, et al.
A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance.Other primary literatureHuman & animalActiveNature medicine2016
Jang C, Oh SF, Wada S, et al.
Metformin inhibits Branched Chain Amino Acid (BCAA) derived ketoacidosis and promotes metabolic homeostasis in MSUD.Other primary literatureAnimalActiveScientific reports2016
S Sonnet D, N O'Leary M, A Gutierrez M, et al.
Discriminative Ability of Plasma Branched-Chain Amino Acid Levels for Glucose Intolerance in Families At Risk for Type 2 Diabetes.Other primary literatureHumanActiveMetabolic syndrome and related disorders2016
Jainandunsing S, Wattimena JL, Verhoeven AJ, et al.
Impact of branched-chain amino acid supplementation on survival in patients with advanced hepatocellular carcinoma treated with sorafenib: A multicenter retrospective cohort study.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2016
Imanaka K, Ohkawa K, Tatsumi T, et al.
Branched-chain amino acid-enriched nutrient increases blood platelet count in patients after endoscopic injection sclerotherapy.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2016
Furuichi Y, Imai Y, Miyata Y, et al.
The role of two branched-chain amino acid transporters in Staphylococcus aureus growth, membrane fatty acid composition and virulence.Other primary literatureHumanActiveMolecular microbiology2016
Kaiser JC, Sen S, Sinha A, et al.
Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.Other primary literatureHuman & animalActiveScience (New York, N.Y.)2016
Mayers JR, Torrence ME, Danai LV, et al.
Effects and feasibility of exercise therapy combined with branched-chain amino acid supplementation on muscle strengthening in frail and pre-frail elderly people requiring long-term care: a crossover trial.Randomized controlled trialHumanActiveApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2016
Ikeda T, Aizawa J, Nagasawa H, et al.
Defective branched chain amino acid catabolism contributes to cardiac dysfunction and remodeling following myocardial infarction.Other primary literatureAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2016
Wang W, Zhang F, Xia Y, et al.
The Relationship between Branched-Chain Amino Acid Related Metabolomic Signature and Insulin Resistance: A Systematic Review.Systematic reviewHumanActiveJournal of diabetes research2016
Zhao X, Han Q, Liu Y, et al.
Branched-Chain Amino Acid-Rich Supplements Containing Microelements Have Antioxidant Effects on Nonalcoholic Steatohepatitis in Mice.Other primary literatureAnimalActiveJPEN. Journal of parenteral and enteral nutrition2016
Tanaka H, Fukahori S, Baba S, et al.
In a single-blind, matched group design: branched-chain amino acid supplementation and resistance training maintains lean body mass during a caloric restricted diet.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2016
Dudgeon WD, Kelley EP, Scheett TP
The data do not seem to support a benefit to BCAA supplementation during periods of caloric restriction.Other primary literatureHumanActiveJournal of the International Society of Sports Nutrition2016
Dieter BP, Schoenfeld BJ, Aragon AA
Post-exercise branched chain amino acid supplementation does not affect recovery markers following three consecutive high intensity resistance training bouts compared to carbohydrate supplementation.Randomized controlled trialHumanActiveJournal of the International Society of Sports Nutrition2016
Kephart WC, Mumford PW, McCloskey AE, et al.
Alterations in protein and amino acid metabolism in rats fed a branched-chain amino acid- or leucine-enriched diet during postprandial and postabsorptive states.Other primary literatureUnknownActiveNutrition & metabolism2016
Holecek M, Siman P, Vodenicarovova M, et al.
Impact of Branched-Chain Amino Acid-Enriched Nutrient on liver Cirrhosis with Hepatocellular Carcinoma Undergoing Transcatheter Arterial Chemoembolization in Barcelona Clinic Liver Cancer Stage B: A Prospective Study.Other primary literatureHumanActiveJournal of Nippon Medical School = Nippon Ika Daigaku zasshi2016
Shiozawa S, Usui T, Kuhara K, et al.
High Leucine Diets Stimulate Cerebral Branched-Chain Amino Acid Degradation and Modify Serotonin and Ketone Body Concentrations in a Pig Model.Other primary literatureAnimalActivePloS one2016
Wessels AG, Kluge H, Hirche F, et al.
Effects of straight alkyl chain, extra hydroxylated alkyl chain and branched chain amino acids on gastric emptying evaluated using a non-invasive breath test in conscious rats.Other primary literatureAnimalActiveJournal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi2016
Uchida M, Kobayashi O, Iwasawa K, et al.
Branched-Chain Amino Acid Supplementation in Combination with Voluntary Running Improves Body Composition in Female C57BL/6 Mice.Other primary literatureAnimalActiveJournal of dietary supplements2016
Platt KM, Charnigo RJ, Shertzer HG, et al.
Glucose supplementation stimulates peripheral branched-chain amino acid catabolism in lactating dairy cows during essential amino acid infusions.Other primary literatureAnimalActiveJournal of dairy science2016
Nichols K, Kim JJM, Carson M, et al.
Disorders of branched chain amino acid metabolism.Other primary literatureUnknownActiveTranslational science of rare diseases2016
Manoli I, Venditti CP
Branched-Chain Amino Acid Levels Are Related with Surrogates of Disturbed Lipid Metabolism among Older Men.Other primary literatureUnknownActiveFrontiers in medicine2016
Kujala UM, Peltonen M, Laine MK, et al.
Nanoparticles Suitable for BCAA Isolation Can Serve for Use in Magnetic Lipoplex-Based Delivery System for L, I, V, or R-rich Antimicrobial Peptides.Other primary literatureUnknownActiveMaterials (Basel, Switzerland)2016
Vesely R, Jelinkova P, Hegerova D, et al.
The Effect of BCAA and ISO-WHEY Oral Nutritional Supplements on Dialysis Adequacy.Other primary literatureUnknownActiveNephro-urology monthly2016
Afaghi E, Tayebi A, Ebadi A, et al.
Metabolic and molecular responses to leucine-enriched branched chain amino acid supplementation in the skeletal muscle of alcoholic cirrhosis.Other primary literatureHumanActiveHepatology (Baltimore, Md.)2015
Tsien C, Davuluri G, Singh D, et al.
Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans.Other primary literatureHumanActiveDiabetologia2015
Glynn EL, Piner LW, Huffman KM, et al.
Branched-chain amino acid supplementation promotes aerobic growth of Salmonella Typhimurium under nitrosative stress conditions.Other primary literatureAnimalActiveArchives of microbiology2015
Park YM, Lee HJ, Jeong JH, et al.
Two randomized controlled studies comparing the nutritional benefits of branched-chain amino acid (BCAA) granules and a BCAA-enriched nutrient mixture for patients with esophageal varices after endoscopic treatment.Randomized controlled trialHumanActiveJournal of gastroenterology2015
Sakai Y, Iwata Y, Enomoto H, et al.
Effect of branched-chain amino acid supplementation on functional liver regeneration in patients undergoing portal vein embolization and sequential hepatectomy: a randomized controlled trial.Randomized controlled trialHumanActiveJournal of gastroenterology2015
Beppu T, Nitta H, Hayashi H, et al.
Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease.Other primary literatureHumanActiveAmino acids2015
Lake AD, Novak P, Shipkova P, et al.
Hypervalinemia and hyperleucine-isoleucinemia caused by mutations in the branched-chain-amino-acid aminotransferase gene.Other primary literatureHumanActiveJournal of inherited metabolic disease2015
Wang XL, Li CJ, Xing Y, et al.
Effects of dietary branched-chain amino acid supplementation on growth and skeletal muscle cellularity in Japanese amberjack Seriola quinqueradiataOther primary literatureUnknownUnknownFish Sci2015
Kawanago M, Takemura S, Ishizuka R, et al.
Intermediaries of branched chain amino acid metabolism induce fetal hemoglobin, and repress SOX6 and BCL11A, in definitive erythroid cells.Other primary literatureHumanActiveBlood cells, molecules & diseases2015
Karkashon S, Raghupathy R, Bhatia H, et al.
Changes in body composition in heart failure patients after a resistance exercise program and branched chain amino acid supplementation - Letter to Editor.Other primary literatureHumanActiveClinical nutrition (Edinburgh, Scotland)2015
Shamoto H, Wakabayashi H, Maeda K
The role of branched chain amino acid and tryptophan metabolism in rat's behavioral diversity: Intertwined peripheral and brain effects.Other primary literatureAnimalActiveEuropean neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology2015
Asor E, Stempler S, Avital A, et al.
Octanoic acid promotes branched-chain amino acid catabolisms via the inhibition of hepatic branched-chain alpha-keto acid dehydrogenase kinase in rats.Other primary literatureAnimalActiveMetabolism: clinical and experimental2015
Kadota Y, Toyoda T, Hayashi-Kato M, et al.
Elevation of branched-chain amino acid levels in diabetes and NAFL and changes with antidiabetic drug treatment.Other primary literatureHumanActiveObesity research & clinical practice2015
Iwasa M, Ishihara T, Mifuji-Moroka R, et al.
Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.Other primary literatureAnimalActiveNature communications2015
Mansfeld J, Urban N, Priebe S, et al.
Acetohydroxyacid synthase FgIlv2 and FgIlv6 are involved in BCAA biosynthesis, mycelial and conidial morphogenesis, and full virulence in Fusarium graminearum.Other primary literatureUnknownActiveScientific reports2015
Liu X, Han Q, Xu J, et al.
Impact of the branched-chain amino acid to tyrosine ratio and branched-chain amino acid granule therapy in patients with hepatocellular carcinoma: A propensity score analysis.Other primary literatureHumanActiveJournal of gastroenterology and hepatology2015
Tada T, Kumada T, Toyoda H, et al.
Combined correlation-based network and mQTL analyses efficiently identified loci for branched-chain amino acid, serine to threonine, and proline metabolism in tomato seeds.Other primary literatureUnknownCorrectedThe Plant journal : for cell and molecular biology2015
Toubiana D, Batushansky A, Tzfadia O, et al.
Role of BrnQ1 and BrnQ2 in branched-chain amino acid transport and virulence in Staphylococcus aureus.Other primary literatureHuman & animalActiveInfection and immunity2015
Kaiser JC, Omer S, Sheldon JR, et al.
Importance of branched-chain amino acid utilization in Francisella intracellular adaptation.Other primary literatureAnimalActiveInfection and immunity2015
Gesbert G, Ramond E, Tros F, et al.
Role of branched-chain amino acid transport in Bacillus subtilis CodY activity.Other primary literatureUnknownActiveJournal of bacteriology2015
Belitsky BR
Efficacy and safety of oral branched-chain amino acid supplementation in patients undergoing interventions for hepatocellular carcinoma: a meta-analysis.Meta-analysisHumanActiveNutrition journal2015
Chen L, Chen Y, Wang X, et al.
Inflammation and ER stress regulate branched-chain amino acid uptake and metabolism in adipocytes.Other primary literatureAnimalActiveMolecular endocrinology (Baltimore, Md.)2015
Burrill JS, Long EK, Reilly B, et al.
Prognostic Impact of Visceral Fat Amount and Branched-Chain Amino Acids (BCAA) in Hepatocellular Carcinoma.Other primary literatureHumanActiveAnnals of surgical oncology2015
Higashi T, Hayashi H, Kaida T, et al.
Intermediate Levels of Bacillus subtilis CodY Activity Are Required for Derepression of the Branched-Chain Amino Acid Permease, BraB.Other primary literatureUnknownActivePLoS genetics2015
Belitsky BR, Brinsmade SR, Sonenshein AL
Effects of acute exposure to increased plasma branched-chain amino acid concentrations on insulin-mediated plasma glucose turnover in healthy young subjects.Randomized controlled trialHumanActivePloS one2015
Everman S, Mandarino LJ, Carroll CC, et al.
Dexamethasone and BCAA Failed to Modulate Muscle Mass and mTOR Signaling in GH-Deficient Rats.Other primary literatureAnimalActivePloS one2015
Nishida H, Ikegami A, Kaneko C, et al.
Branched-chain amino acid and lysine deficiencies exert different effects on mammary translational regulation.Other primary literatureAnimalActiveJournal of dairy science2015
Doelman J, Kim JJ, Carson M, et al.
Efficacy, dosage, and duration of action of branched chain amino Acid therapy for traumatic brain injury.Other primary literatureUnknownActiveFrontiers in neurology2015
Elkind JA, Lim MM, Johnson BN, et al.
The Impaired Function of Macrophages Induced by Strenuous Exercise Could Not Be Ameliorated by BCAA Supplementation.Other primary literatureAnimalActiveNutrients2015
Xiao W, Chen P, Liu X, et al.
Effects of intraduodenal infusion of the branched-chain amino acid leucine on ad libitum eating, gut motor and hormone functions, and glycemia in healthy men.Randomized controlled trialHumanActiveThe American journal of clinical nutrition2015
Steinert RE, Landrock MF, Ullrich SS, et al.
Determination of essentiality and regulatory function of staphylococcal YeaZ in branched-chain amino acid biosynthesis.Other primary literatureUnknownActiveVirulence2015
Lei T, Yang J, Ji Y
Additional BCAA-enriched nutrient mixture improves the nutritional condition in cirrhotic patients with hypoalbuminemia despite treatment with regular BCAA granules: A pilot study.Other primary literatureHumanActiveThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2015
Fukui A, Kawabe N, Hashimoto S, et al.
[Impact of glutamine, eicosapntemacnioc acid, branched-chain amino acid supplements on nutritional status and treatment compliance of esophageal cancer patients on concurrent chemoradiotherapy and gastric cancer patients on chemotherapy].Randomized controlled trialHumanActiveZhonghua yi xue za zhi2015
Cong M, Song C, Zou B, et al.
Cloning and characterization of a novel fold-type I branched-chain amino acid aminotransferase from the hyperthermophilic archaeon Thermococcus sp. CKU-1.Other primary literatureUnknownActiveExtremophiles : life under extreme conditions2014
Uchida Y, Hayashi H, Washio T, et al.
Voluntary exercise under a food restriction condition decreases blood branched-chain amino acid levels, in addition to improvement of glucose and lipid metabolism, in db mice, animal model of type 2 diabetes.Other primary literatureHuman & animalActiveEnvironmental health and preventive medicine2014
Marchianti AC, Arimura E, Ushikai M, et al.
Validation of the association between a branched chain amino acid metabolite profile and extremes of coronary artery disease in patients referred for cardiac catheterization.Other primary literatureHumanActiveAtherosclerosis2014
Bhattacharya S, Granger CB, Craig D, et al.
Branched-chain amino acid supplementation in adults with cirrhosis and porto-systemic encephalopathy: systematic review.Meta-analysisHumanActiveClinical nutrition (Edinburgh, Scotland)2014
Metcalfe EL, Avenell A, Fraser A
Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism.Other primary literatureAnimalActiveCell metabolism2014
Shin AC, Fasshauer M, Filatova N, et al.
The feasibility of assessing branched-chain amino acid metabolism in cellular models of prostate cancer with hyperpolarized [1-(13)C]-ketoisocaproate.Other primary literatureHumanActiveMagnetic resonance imaging2014
Billingsley KL, Park JM, Josan S, et al.
Branched-chain amino acid metabolism: from rare Mendelian diseases to more common disorders.ReviewHuman & animalActiveHuman molecular genetics2014
Burrage LC, Nagamani SC, Campeau PM, et al.
FgIlv5 is required for branched-chain amino acid biosynthesis and full virulence in Fusarium graminearum.Other primary literatureUnknownActiveMicrobiology (Reading, England)2014
Liu X, Wang J, Xu J, et al.
Arabidopsis and maize RidA proteins preempt reactive enamine/imine damage to branched-chain amino acid biosynthesis in plastids.Other primary literatureAnimalActiveThe Plant cell2014
Niehaus TD, Nguyen TN, Gidda SK, et al.
The specificity and kinetic mechanism of branched-chain amino acid aminotransferase from Escherichia coli studied with a new improved coupled assay procedure and the enzyme's potential for biocatalysis.Other primary literatureUnknownActiveThe FEBS journal2014
Yu X, Wang X, Engel PC
Oral supplementation with branched-chain amino acid granules prevents hepatocarcinogenesis in patients with hepatitis C-related cirrhosis: A propensity score analysis.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2014
Tada T, Kumada T, Toyoda H, et al.
Clinical significance of therapy using branched-chain amino acid granules in patients with liver cirrhosis and hepatocellular carcinoma.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2014
Nishikawa H, Osaki Y
Effects of eccentric exercise on branched-chain amino acid profiles in rat serum and skeletal muscle.Other primary literatureAnimalActiveJournal of animal physiology and animal nutrition2014
Qun Z, Xinkai Y, Jing W
Emerging Roles of Branched-Chain Amino Acid Supplementation in Human Diseases.ReviewUnknownActiveInternational scholarly research notices2014
Tamanna N, Mahmood N
PGC-1α-mediated branched-chain amino acid metabolism in the skeletal muscle.Other primary literatureAnimalActivePloS one2014
Hatazawa Y, Tadaishi M, Nagaike Y, et al.
Effects of leucine supplementation and serum withdrawal on branched-chain amino acid pathway gene and protein expression in mouse adipocytes.Other primary literatureAnimalActivePloS one2014
Kitsy A, Carney S, Vivar JC, et al.
Effects of Supplementation with BCAA and L-glutamine on Blood Fatigue Factors and Cytokines in Juvenile Athletes Submitted to Maximal Intensity Rowing Performance.Other primary literatureUnknownActiveJournal of physical therapy science2014
Koo GH, Woo J, Kang S, et al.
Branched-chain amino acid-rich diet improves skeletal muscle wasting caused by cigarette smoke in rats.Other primary literatureAnimalActiveThe Journal of toxicological sciences2014
Tomoda K, Kubo K, Hino K, et al.
Branched-chain amino acid granules improve the non-protein respiratory quotient after radiofrequency ablation.Other primary literatureHumanActiveInternal medicine (Tokyo, Japan)2014
Saito M, Yano Y, Minami A, et al.
Is administrating branched-chain amino acid-enriched nutrition achieved symptom-free in malnourished cirrhotic patients?Other primary literatureUnknownActiveJournal of clinical biochemistry and nutrition2014
Tsuda Y, Fukui H, Sujishi T, et al.
[Meta-analysis of branched chain amino acid-enriched nutrition to improve hepatic function in patients undergoing hepatic operation].Meta-analysisHumanActiveZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2014
Shu X, Kang K, Zhong J, et al.
Clinical significance of early interventional therapy of branched-chain amino acid granules in patients with hepatocellular carcinoma: propensity score matching analysis.Other primary literatureHumanActiveInternational journal of oncology2014
Nishikawa H, Kita R, Kimura T, et al.
Branched-chain amino acid requirements for enterally fed term neonates in the first month of life.Randomized controlled trialHumanActiveThe American journal of clinical nutrition2014
de Groof F, Huang L, van Vliet I, et al.
Branched chain amino acid suppressed insulin-initiated proliferation of human cancer cells through induction of autophagy.Other primary literatureHumanCorrectedAnticancer research2014
Wubetu GY, Utsunomiya T, Ishikawa D, et al.
[Synthesis reduction of central neurotransmitter 5-hydroxytryptamine by branched chain amino acid and associated antagonists improves postoperative fatigue syndrome].Other primary literatureAnimalActiveZhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery2014
Dong Q, Zhang X, Yu Z, et al.
Branched-chain amino acid supplementation: impact on signaling and relevance to critical illness.ReviewHumanActiveWiley interdisciplinary reviews. Systems biology and medicine2013
Mattick JSA, Mattick JSA, Kamisoglu K, et al.
Additional effects of taurine on the benefits of BCAA intake for the delayed-onset muscle soreness and muscle damage induced by high-intensity eccentric exercise.Randomized controlled trialHumanActiveAdvances in experimental medicine and biology2013
Ra SG, Miyazaki T, Ishikura K, et al.
The efficacy of nocturnal administration of branched-chain amino acid granules to improve quality of life in patients with cirrhosis.Randomized controlled trialHumanActiveJournal of gastroenterology2013
Hidaka H, Nakazawa T, Kutsukake S, et al.
Oral branched-chain amino acid supplements that reduce brain serotonin during exercise in rats also lower brain catecholamines.Other primary literatureHuman & animalActiveAmino acids2013
Choi S, Disilvio B, Fernstrom MH, et al.
Substrate specificity of human carnitine acetyltransferase: Implications for fatty acid and branched-chain amino acid metabolism.Other primary literatureHumanActiveBiochimica et biophysica acta2013
Violante S, Ijlst L, Ruiter J, et al.
Valine, the branched-chain amino acid, suppresses hepatitis C virus RNA replication but promotes infectious particle formation.Other primary literatureHumanActiveBiochemical and biophysical research communications2013
Ishida H, Kato T, Takehana K, et al.
Long-term Branched Chain Amino Acid Supplementation Ameliorates Diethylnitrosamine-induced Liver Glutathione S-transferase-p Positivity in Zucker Fatty Rats.Other primary literatureUnknownActiveJournal of clinical and experimental hepatology2013
Ishizaki S, Nishiyama M, Hagiwara A
Branched-chain amino acid biosynthesis inhibitors: herbicide efficacy is associated with an induced carbon-nitrogen imbalance.Other primary literatureUnknownActiveJournal of plant physiology2013
Zabalza A, Zulet A, Gil-Monreal M, et al.
Adipose transplant for inborn errors of branched chain amino acid metabolism in mice.Other primary literatureAnimalActiveMolecular genetics and metabolism2013
Zimmerman HA, Olson KC, Chen G, et al.
General control nonderepressible 2 (GCN2) kinase protects oligodendrocytes and white matter during branched-chain amino acid deficiency in mice.Other primary literatureHuman & animalActiveThe Journal of biological chemistry2013
She P, Bunpo P, Cundiff JK, et al.
Branched-chain amino acid intake and the risk of diabetes in a Japanese community: the Takayama study.Other primary literatureHumanActiveAmerican journal of epidemiology2013
Nagata C, Nakamura K, Wada K, et al.
Partial deficiency of isoleucine impairs root development and alters transcript levels of the genes involved in branched-chain amino acid and glucosinolate metabolism in Arabidopsis.Other primary literatureUnknownActiveJournal of experimental botany2013
Yu H, Zhang F, Wang G, et al.
Potential role of branched-chain amino acid catabolism in regulating fat oxidation.ReviewHuman & animalActiveExercise and sport sciences reviews2013
Kainulainen H, Hulmi JJ, Kujala UM
The effect of long-term supplementation with branched-chain amino acid granules in patients with hepatitis C virus-related hepatocellular carcinoma after radiofrequency thermal ablation.Other primary literatureHumanActiveJournal of clinical gastroenterology2013
Nishikawa H, Osaki Y, Iguchi E, et al.
Genome-wide analysis of branched-chain amino acid levels in Arabidopsis seeds.Other primary literatureUnknownActiveThe Plant cell2013
Angelovici R, Lipka AE, Deason N, et al.
Effects of branched-chain amino acid granules on serum albumin level and prognosis are dependent on treatment adherence in patients with liver cirrhosis.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2013
Takaguchi K, Moriwaki H, Doyama H, et al.
Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents.Other primary literatureHumanActivePediatric obesity2013
McCormack SE, Shaham O, McCarthy MA, et al.
Characterization of BcaA, a putative classical autotransporter protein in Burkholderia pseudomallei.Other primary literatureHuman & animalActiveInfection and immunity2013
Campos CG, Borst L, Cotter PA
Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity.Other primary literatureHuman & animalActiveAmerican journal of physiology. Endocrinology and metabolism2013
Lackey DE, Lynch CJ, Olson KC, et al.
Metabolite profiling identifies a branched chain amino acid signature in acute cardioembolic stroke.Other primary literatureHuman & animalActiveStroke2013
Kimberly WT, Wang Y, Pham L, et al.
Leucine and protein metabolism in obese Zucker rats.Other primary literatureAnimalActivePloS one2013
She P, Olson KC, Kadota Y, et al.
Branched-chain amino acid supplementation reduces oxidative stress and prolongs survival in rats with advanced liver cirrhosis.Other primary literatureAnimalActivePloS one2013
Iwasa M, Kobayashi Y, Mifuji-Moroka R, et al.
The antifungal eugenol perturbs dual aromatic and branched-chain amino acid permeases in the cytoplasmic membrane of yeast.Other primary literatureUnknownActivePloS one2013
Darvishi E, Omidi M, Bushehri AA, et al.
Branched chain amino acid suppresses hepatocellular cancer stem cells through the activation of mammalian target of rapamycin.Other primary literatureHumanActivePloS one2013
Nishitani S, Horie M, Ishizaki S, et al.
Effect of Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding on branched-chain amino acid metabolism.Other primary literatureHumanActiveDiabetes2013
Magkos F, Bradley D, Schweitzer GG, et al.
Assessing the age-dependent optimal dietary branched-chain amino acid ratio in growing chicken by application of a nonlinear modeling procedure.Other primary literatureAnimalActivePoultry science2013
Pastor A, Wecke C, Liebert F
Drosophila miR-277 controls branched-chain amino acid catabolism and affects lifespan.Other primary literatureAnimalActiveRNA biology2013
Esslinger SM, Schwalb B, Helfer S, et al.
Branched-chain amino Acid plus glucose supplement reduces exercise-induced delayed onset muscle soreness in college-age females.Other primary literatureUnknownActiveISRN nutrition2013
Leahy DT, Pintauro SJ
Effect of BCAA intake during endurance exercises on fatigue substances, muscle damage substances, and energy metabolism substances.Other primary literatureUnknownActiveJournal of exercise nutrition & biochemistry2013
Kim DH, Kim SH, Jeong WS, et al.
Branched-chain amino acid deficiency stabilizes insulin-induced vascular endothelial growth factor mRNA in hepatocellular carcinoma cells.Other primary literatureHumanActiveJournal of cellular biochemistry2012
Miuma S, Ichikawa T, Arima K, et al.
Branched-chain amino acid levels are associated with improvement in insulin resistance with weight loss.Randomized controlled trialHumanActiveDiabetologia2012
Shah SH, Crosslin DR, Haynes CS, et al.
Branched-chain amino acid-enriched nutrients improve nutritional and metabolic abnormalities in the early post-transplant period after living donor liver transplantation.Randomized controlled trialHumanActiveJournal of hepato-biliary-pancreatic sciences2012
Yoshida R, Yagi T, Sadamori H, et al.
Changes in transcription during recovery from heat injury in Salmonella typhimurium and effects of BCAA on recovery.Other primary literatureUnknownActiveAmino acids2012
Hsu-Ming W, Naito K, Kinoshita Y, et al.
Enzymology of the branched-chain amino acid oxidation disorders: the valine pathway.Other primary literatureHuman & animalActiveJournal of inherited metabolic disease2012
Wanders RJ, Duran M, Loupatty FJ
Branched-chain amino acid-enriched nutrients stimulate antioxidant DNA repair in a rat model of liver injury induced by carbon tetrachloride.Other primary literatureAnimalActiveMolecular biology reports2012
Ichikawa K, Okabayashi T, Shima Y, et al.
Beneficial effect of branched-chain amino acid supplementation on glycemic control in chronic hepatitis C patients with insulin resistance: implications for type 2 diabetes.Randomized controlled trialHumanActiveMetabolism: clinical and experimental2012
Takeshita Y, Takamura T, Kita Y, et al.
Preventive effects of branched-chain amino acid supplementation on the spontaneous development of hepatic preneoplastic lesions in C57BL/KsJ-db/db obese mice.Other primary literatureAnimalActiveCarcinogenesis2012
Terakura D, Shimizu M, Iwasa J, et al.
The branched-chain amino acid aminotransferase encoded by ilvE is involved in acid tolerance in Streptococcus mutans.Other primary literatureUnknownActiveJournal of bacteriology2012
Santiago B, MacGilvray M, Faustoferri RC, et al.
Valine, a branched-chain amino Acid, reduced HCV viral load and led to eradication of HCV by interferon therapy in a decompensated cirrhotic patient.Other primary literatureUnknownActiveCase reports in gastroenterology2012
Kawaguchi T, Torimura T, Takata A, et al.
Clofibrate-induced reduction of plasma branched-chain amino acid concentrations impairs glucose tolerance in rats.Other primary literatureAnimalActiveJPEN. Journal of parenteral and enteral nutrition2012
Kadota Y, Kazama S, Bajotto G, et al.
The effects of 8 weeks of heavy resistance training and branched-chain amino acid supplementation on body composition and muscle performance.Other primary literatureHumanActiveNutrition and health2012
Spillane M, Emerson C, Willoughby DS
Effect of branched-chain amino acid-enriched nutritional supplementation on interferon therapy in Japanese patients with chronic hepatitis C virus infection: a retrospective study.Other primary literatureHumanActiveVirology journal2012
Nagao Y, Kawaguchi T, Ide T, et al.
A protein-leucine supplement increases branched-chain amino acid and nitrogen turnover but not performance.Randomized controlled trialHumanActiveMedicine and science in sports and exercise2012
Nelson AR, Phillips SM, Stellingwerff T, et al.
Impaired branched chain amino acid metabolism alters feeding behavior and increases orexigenic neuropeptide expression in the hypothalamus.Other primary literatureAnimalActiveThe Journal of endocrinology2012
Purpera MN, Shen L, Taghavi M, et al.
Long-term branched-chain amino acid supplementation improves glucose tolerance in patients with nonalcoholic steatohepatitis-related cirrhosis.Other primary literatureHumanActiveInternal medicine (Tokyo, Japan)2012
Miyake T, Abe M, Furukawa S, et al.
Effect of branched-chain amino acid supplementation on the oxidized/reduced state of plasma albumin in rats with chronic liver disease.Other primary literatureUnknownActiveJournal of clinical biochemistry and nutrition2012
Kuwahata M, Kubota H, Katsukawa M, et al.
Branched-chain amino acid supplementation during a 100-km ultra-marathon--a randomized controlled trial.Randomized controlled trialHumanActiveJournal of nutritional science and vitaminology2012
Knechtle B, Mrazek C, Wirth A, et al.
Branched-chain amino acid treatment before transcatheter arterial chemoembolization for hepatocellular carcinoma.Other primary literatureHumanActiveWorld journal of gastroenterology2012
Nishikawa H, Osaki Y, Inuzuka T, et al.
Early administration of branched-chain amino acid granules.ReviewHumanActiveWorld journal of gastroenterology2012
Ishikawa T
Combination of branched-chain amino acid and angiotensin-converting enzyme inhibitor improves liver fibrosis progression in patients with cirrhosis.Randomized controlled trialHumanActiveMolecular medicine reports2012
Yoshiji H, Noguchi R, Ikenaka Y, et al.
Branched chain amino acid profile in early chronic kidney disease.Other primary literatureHumanActiveSaudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia2012
Kumar MA, Bitla AR, Raju KV, et al.
Effect of branched-chain amino acid supplementation during unloading on regulatory components of protein synthesis in atrophied soleus muscles.Other primary literatureAnimalActiveEuropean journal of applied physiology2011
Bajotto G, Sato Y, Kitaura Y, et al.
Acute hyperammonemia activates branched-chain amino acid catabolism and decreases their extracellular concentrations: different sensitivity of red and white muscle.Other primary literatureHuman & animalActiveAmino acids2011
Holecek M, Kandar R, Sispera L, et al.
Oral supplementation with carbohydrate- and branched-chain amino acid-enriched nutrients improves postoperative quality of life in patients undergoing hepatic resection.Randomized controlled trialHumanActiveAmino acids2011
Okabayashi T, Iyoki M, Sugimoto T, et al.
Prognostic impact of preoperative the branched-chain amino acid to the tyrosine ratio in hepatocellular carcinoma patients after initial hepatectomy.Other primary literatureHumanActiveJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2011
Mizuguchi T, Kawamoto M, Meguro M, et al.
Cluster analysis of indicators of liver functional and preoperative low branched-chain amino acid tyrosine ration indicate a high risk of early recurrence in analysis of 165 hepatocellular carcinoma patients after initial hepatectomy.Other primary literatureHumanActiveSurgery2011
Nakamura Y, Mizuguchi T, Kawamoto M, et al.
Branched-chain amino acid supplemented diet during maternal food restriction prevents developmental hypertension in adult rat offspring.Other primary literatureUnknownActiveJournal of developmental origins of health and disease2011
Fujii T, Yura S, Tatsumi K, et al.
Branched-chain amino acid metabolism in heart disease: an epiphenomenon or a real culprit?ReviewHuman & animalActiveCardiovascular research2011
Huang Y, Zhou M, Sun H, et al.
The genetic architecture of branched-chain amino acid accumulation in tomato fruits.Other primary literatureUnknownActiveJournal of experimental botany2011
Kochevenko A, Fernie AR
The ZmASR1 protein influences branched-chain amino acid biosynthesis and maintains kernel yield in maize under water-limited conditions.Other primary literatureUnknownActivePlant physiology2011
Virlouvet L, Jacquemot MP, Gerentes D, et al.
Effects of late evening snack including branched-chain amino acid on the function of hepatic parenchymal cells in patients with liver cirrhosis.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2011
Koreeda C, Seki T, Okazaki K, et al.
Anti-hypoalbuminemic effect of branched-chain amino acid granules in patients with liver cirrhosis is independent of dietary energy and protein intake.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2011
Yatsuhashi H, Ohnishi Y, Nakayama S, et al.
Role of isovaleryl-CoA dehydrogenase and short branched-chain acyl-CoA dehydrogenase in the metabolism of valproic acid: implications for the branched-chain amino acid oxidation pathway.Other primary literatureUnknownActiveDrug metabolism and disposition: the biological fate of chemicals2011
Luís PB, Ruiter JP, Ijlst L, et al.
Analysis of the LIV system of Campylobacter jejuni reveals alternative roles for LivJ and LivK in commensalism beyond branched-chain amino acid transport.Other primary literatureHuman & animalActiveJournal of bacteriology2011
Ribardo DA, Hendrixson DR
Oral branched-chain amino acid granules reduce the incidence of hepatocellular carcinoma and improve event-free survival in patients with liver cirrhosis.Other primary literatureHumanActiveDigestive diseases (Basel, Switzerland)2011
Hayaishi S, Chung H, Kudo M, et al.
The effects of branched-chain amino acid granules on the accumulation of tissue triglycerides and uncoupling proteins in diet-induced obese mice.Other primary literatureAnimalActiveEndocrine journal2011
Arakawa M, Masaki T, Nishimura J, et al.
Branched-chain amino acid supplementation lowers perceived exertion but does not affect performance in untrained males.Randomized controlled trialHumanActiveJournal of strength and conditioning research2011
Greer BK, White JP, Arguello EM, et al.
Effects of branched-chain amino acid supplementation on plasma concentrations of free amino acids, insulin, and energy substrates in young men.Other primary literatureHumanActiveJournal of nutritional science and vitaminology2011
Zhang Y, Kobayashi H, Mawatari K, et al.
Higher branched-chain amino acid intake is associated with a lower prevalence of being overweight or obese in middle-aged East Asian and Western adults.Other primary literatureHumanActiveThe Journal of nutrition2011
Qin LQ, Xun P, Bujnowski D, et al.
Effects of BCAA, arginine and carbohydrate combined drink on post-exercise biochemical response and psychological condition.Randomized controlled trialHumanCorrectedThe Chinese journal of physiology2011
Hsu MC, Chien KY, Hsu CC, et al.
Effect of Oral Supplementation with Branched-chain Amino Acid (BCAA) during Radiotherapy in Patients with Hepatocellular Carcinoma: A Double-Blind Randomized Study.Other primary literatureUnknownActiveCancer research and treatment2011
Lee IJ, Seong J, Bae JI, et al.
Effects of branched-chain amino acid infusions on liver regeneration and plasma amino acid patterns in partially hepatectomized rats.Other primary literatureAnimalActiveHepato-gastroenterology2011
Kim SJ, Kim DG, Lee MD
Exercise x BCAA Supplementation in Young Trained Rats: What are their Effects on Body Growth?Other primary literatureUnknownActiveJournal of sports science & medicine2011
de Campos-Ferraz PL, Ribeiro SM, Luz Sdos S, et al.
Imaging of branched chain amino acid metabolism in tumors with hyperpolarized 13C ketoisocaproate.Other primary literatureAnimalActiveInternational journal of cancer2010
Karlsson M, Jensen PR, in 't Zandt R, et al.
L-citrulline-malate influence over branched chain amino acid utilization during exercise.Randomized controlled trialHumanActiveEuropean journal of applied physiology2010
Sureda A, Córdova A, Ferrer MD, et al.
Regulation of branched-chain amino acid catabolism: glucose limitation enhances the component of isovalerylspiramycin for the bitespiramycin production.Other primary literatureUnknownActiveBioprocess and biosystems engineering2010
Wang YH, Wu CH, Chu J, et al.
Preoperative oral supplementation with carbohydrate and branched-chain amino acid-enriched nutrient improves insulin resistance in patients undergoing a hepatectomy: a randomized clinical trial using an artificial pancreas.Randomized controlled trialHumanActiveAmino acids2010
Okabayashi T, Nishimori I, Yamashita K, et al.
Branched-chain amino acid supplementation promotes survival and supports cardiac and skeletal muscle mitochondrial biogenesis in middle-aged mice.Other primary literatureAnimalActiveCell metabolism2010
D'Antona G, Ragni M, Cardile A, et al.
Three targets of branched-chain amino acid supplementation in the treatment of liver disease.ReviewHumanActiveNutrition (Burbank, Los Angeles County, Calif.)2010
Holecek M
The effects of branched-chain amino acid interactions on growth performance, blood metabolites, enzyme kinetics and transcriptomics in weaned pigs.Other primary literatureAnimalActiveThe British journal of nutrition2010
Wiltafsky MK, Pfaffl MW, Roth FX
Branched-chain amino acid metabolon: interaction of glutamate dehydrogenase with the mitochondrial branched-chain aminotransferase (BCATm).Other primary literatureAnimalActiveThe Journal of biological chemistry2010
Islam MM, Nautiyal M, Wynn RM, et al.
Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels.Other primary literatureAnimalActiveThe Journal of biological chemistry2010
Herman MA, She P, Peroni OD, et al.
Characterization of the branched-chain amino acid aminotransferase enzyme family in tomato.Other primary literatureUnknownActivePlant physiology2010
Maloney GS, Kochevenko A, Tieman DM, et al.
Genetic analysis of pathway regulation for enhancing branched-chain amino acid biosynthesis in plants.Other primary literatureUnknownActiveThe Plant journal : for cell and molecular biology2010
Chen H, Saksa K, Zhao F, et al.
Effects of branched-chain amino acid-enriched nutrient for patients with hepatocellular carcinoma following radiofrequency ablation: a one-year prospective trial.Other primary literatureHumanActiveJournal of gastroenterology and hepatology2010
Kuroda H, Ushio A, Miyamoto Y, et al.
Effect of a late evening snack using branched-chain amino acid-enriched nutrients in patients undergoing hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2010
Harima Y, Yamasaki T, Hamabe S, et al.
Effect of an oral branched chain amino acid-enriched snack in cirrhotic patients with sleep disturbance.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2010
Ichikawa T, Naota T, Miyaaki H, et al.
Branched-chain amino acid supplementation before squat exercise and delayed-onset muscle soreness.Randomized controlled trialHumanActiveInternational journal of sport nutrition and exercise metabolism2010
Shimomura Y, Inaguma A, Watanabe S, et al.
Mechanism of de novo branched-chain amino acid synthesis as an alternative electron sink in hypoxic Aspergillus nidulans cells.Other primary literatureUnknownActiveApplied and environmental microbiology2010
Shimizu M, Fujii T, Masuo S, et al.
Regulation of CodY activity through modulation of intracellular branched-chain amino acid pools.Other primary literatureUnknownActiveJournal of bacteriology2010
Brinsmade SR, Kleijn RJ, Sauer U, et al.
Serum branched-chain amino acid to histidine ratio: a novel metabolomic biomarker of knee osteoarthritis.Other primary literatureHumanActiveAnnals of the rheumatic diseases2010
Zhai G, Wang-Sattler R, Hart DJ, et al.
Disruption of BCAA metabolism in mice impairs exercise metabolism and endurance.Other primary literatureAnimalActiveJournal of applied physiology (Bethesda, Md. : 1985)2010
She P, Zhou Y, Zhang Z, et al.
Volatile profiling reveals intracellular metabolic changes in Aspergillus parasiticus: veA regulates branched chain amino acid and ethanol metabolism.Other primary literatureUnknownActiveBMC biochemistry2010
Roze LV, Chanda A, Laivenieks M, et al.
Branched-Chain Amino Acid Metabolism in Arabidopsis thaliana.Other primary literatureUnknownActiveThe arabidopsis book2010
Binder S
Branched-chain amino acid ingestion can ameliorate soreness from eccentric exercise.Other primary literatureHumanActiveMedicine and science in sports and exercise2010
Jackman SR, Witard OC, Jeukendrup AE, et al.
Effect of intermittent blood volume fluctuation of light resistance exercise after ingestion of the high-protein snacks on plasma branched-chain amino acid concentrations in young adults.Randomized controlled trialHumanActiveJournal of nutritional science and vitaminology2010
Kato Y, Numao S, Miyauchi R, et al.
Branched-chain amino acid catabolism provides precursors for the Type II polyketide antibiotic, actinorhodin, via pathways that are nutrient dependent.Other primary literatureUnknownActiveJournal of industrial microbiology & biotechnology2009
Stirrett K, Denoya C, Westpheling J
Docking and quantitative structure-activity relationship studies for sulfonyl hydrazides as inhibitors of cytosolic human branched-chain amino acid aminotransferase.Other primary literatureHumanActiveMolecular diversity2009
Caballero J, Vergara-Jaque A, Fernández M, et al.
Plasma branched-chain amino acid levels and muscle energy metabolism in patients with chronic obstructive pulmonary disease.Other primary literatureHumanActiveClinical nutrition (Edinburgh, Scotland)2009
Kutsuzawa T, Shioya S, Kurita D, et al.
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance.Other primary literatureHuman & animalCorrectedCell metabolism2009
Newgard CB, An J, Bain JR, et al.
Ecological genomics of Boechera stricta: identification of a QTL controlling the allocation of methionine- vs branched-chain amino acid-derived glucosinolates and levels of insect herbivory.Other primary literatureAnimalActiveHeredity2009
Schranz ME, Manzaneda AJ, Windsor AJ, et al.
Branched chain amino acids supplemented with L-acetylcarnitine versus BCAA treatment in hepatic coma: a randomized and controlled double blind study.Randomized controlled trialHumanActiveEuropean journal of gastroenterology & hepatology2009
Malaguarnera M, Risino C, Cammalleri L, et al.
Inactivation of the ilvB1 gene in Mycobacterium tuberculosis leads to branched-chain amino acid auxotrophy and attenuation of virulence in mice.Other primary literatureAnimalActiveMicrobiology (Reading, England)2009
Awasthy D, Gaonkar S, Shandil RK, et al.
Screening of Streptococcus pneumoniae ABC transporter mutants demonstrates that LivJHMGF, a branched-chain amino acid ABC transporter, is necessary for disease pathogenesis.Other primary literatureAnimalActiveInfection and immunity2009
Basavanna S, Khandavilli S, Yuste J, et al.
Comparative genomics of regulation of fatty acid and branched-chain amino acid utilization in proteobacteria.Other primary literatureUnknownActiveJournal of bacteriology2009
Kazakov AE, Rodionov DA, Alm E, et al.
Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells.Other primary literatureHuman & animalActiveThe Journal of clinical investigation2009
Lu G, Sun H, She P, et al.
Effect of light resistance exercise after ingestion of a high-protein snack on plasma branched-chain amino acid concentrations in young adult females.Randomized controlled trialHumanActiveJournal of nutritional science and vitaminology2009
Kato Y, Sawada A, Numao S, et al.
Effects of squat exercise and branched-chain amino acid supplementation on plasma free amino acid concentrations in young women.Randomized controlled trialHumanActiveJournal of nutritional science and vitaminology2009
Shimomura Y, Kobayashi H, Mawatari K, et al.
Branched-chain amino acid supplementation increases the lactate threshold during an incremental exercise test in trained individuals.Randomized controlled trialHumanActiveJournal of nutritional science and vitaminology2009
Matsumoto K, Koba T, Hamada K, et al.
Branched-chain amino acid-containing dipeptides, identified from whey protein hydrolysates, stimulate glucose uptake rate in L6 myotubes and isolated skeletal muscles.Other primary literatureAnimalActiveJournal of nutritional science and vitaminology2009
Morifuji M, Koga J, Kawanaka K, et al.
Branched-chain amino acid supplements reduced ascites and increased the quality of life in a patient with liver cirrhosis: A case report.Other primary literatureUnknownActiveMolecular medicine reports2009
Itou M, Kawaguchi T, Taniguchi E, et al.
Heating improves poor compliance with branched chain amino acid-rich supplementation in patients with liver cirrhosis: A before-after pilot study.Other primary literatureUnknownActiveMolecular medicine reports2009
Itou M, Kawaguchi T, Taniguchi E, et al.
Branched-chain amino acid supplementation attenuates muscle soreness, muscle damage and inflammation during an intensive training program.Randomized controlled trialHumanActiveThe Journal of sports medicine and physical fitness2009
Matsumoto K, Koba T, Hamada K, et al.
Comparison of the effect of BCAA granules on between decompensated and compensated cirrhosis.Randomized controlled trialHumanActiveHepato-gastroenterology2009
Habu D, Nishiguchi S, Nakatani S, et al.
Inhibitory effect of branched-chain amino acid granules on progression of compensated liver cirrhosis due to hepatitis C virus.Randomized controlled trialHumanActiveJournal of gastroenterology2008
Kobayashi M, Ikeda K, Arase Y, et al.
Regulation of branched-chain amino acid catabolism in rat models for spontaneous type 2 diabetes mellitus.Other primary literatureAnimalActiveBiochemical and biophysical research communications2008
Kuzuya T, Katano Y, Nakano I, et al.
Regulation of taste-active components of meat by dietary branched-chain amino acids; effects of branched-chain amino acid antagonism.Other primary literatureHuman & animalActiveBritish poultry science2008
Imanari M, Kadowaki M, Fujimura S
Auxotrophy accounts for nodulation defect of most Sinorhizobium meliloti mutants in the branched-chain amino acid biosynthesis pathway.Other primary literatureUnknownActiveMolecular plant-microbe interactions : MPMI2008
de las Nieves Peltzer M, Roques N, Poinsot V, et al.
Acrodermatitis enteropathica-like syndrome secondary to branched-chain amino acid deficiency in inborn errors of metabolism.Other primary literatureHumanActivePediatric dermatology2008
Oztürk Y
Suppressive effect of oral administration of branched-chain amino acid granules on oxidative stress and inflammation in HCV-positive patients with liver cirrhosis.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2008
Ohno T, Tanaka Y, Sugauchi F, et al.
Long-term outcome of branched-chain amino acid treatment in patients with liver cirrhosis.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2008
Moriwaki H, Shiraki M, Fukushima H, et al.
Randomized, controlled study of branched chain amino acid-enriched total parenteral nutrition in malnourished patients with gastrointestinal cancer undergoing surgery.Randomized controlled trialHumanActiveThe American surgeon2008
Sun LC, Shih YL, Lu CY, et al.
Branched-chain amino acid-enriched supplementation improves insulin resistance in patients with chronic liver disease.Other primary literatureHumanActiveInternational journal of molecular medicine2008
Kawaguchi T, Nagao Y, Matsuoka H, et al.
Branched-chain amino acid supplementation does not enhance athletic performance but affects muscle recovery and the immune system.ReviewHumanActiveThe Journal of sports medicine and physical fitness2008
Negro M, Giardina S, Marzani B, et al.
Purification of branched-chain amino acid aminotransferase from Helicobacter pylori NCTC 11637.Other primary literatureHuman & animalActiveAmino acids2007
Saito M, Nishimura K, Wakabayashi S, et al.
BCAA-enriched snack improves nutritional state of cirrhosis.Randomized controlled trialHumanActiveNutrition (Burbank, Los Angeles County, Calif.)2007
Nakaya Y, Okita K, Suzuki K, et al.
A novel branched-chain amino acid metabolon. Protein-protein interactions in a supramolecular complex.Other primary literatureHuman & animalActiveThe Journal of biological chemistry2007
Islam MM, Wallin R, Wynn RM, et al.
Branched-chain amino acid metabolism in higher plantsOther primary literatureUnknownUnknownPhysiologia plantarum2007
Binder S, Knill T, Schuster J
Evaluation of the effects of combination therapy with branched-chain amino acid and zinc supplements on nitrogen metabolism in liver cirrhosis.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2007
Hayashi M, Ikezawa K, Ono A, et al.
Oral branched-chain amino acid supplementation improves the oxidized/reduced albumin ratio in patients with liver cirrhosis.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2007
Fukushima H, Miwa Y, Shiraki M, et al.
Branched-chain amino acid supplementation and indicators of muscle damage after endurance exercise.Randomized controlled trialHumanActiveInternational journal of sport nutrition and exercise metabolism2007
Greer BK, Woodard JL, White JP, et al.
Inhibition of PI3-kinase signaling by glucocorticoids results in increased branched-chain amino acid degradation in renal epithelial cells.Other primary literatureAnimalActiveAmerican journal of physiology. Cell physiology2007
Wang X, Hu J, Price SR
Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism.Other primary literatureHuman & animalActiveAmerican journal of physiology. Endocrinology and metabolism2007
She P, Van Horn C, Reid T, et al.
Inhibitory effect of aroma on the bitterness of branched-chain amino acid solutions.Other primary literatureHumanActiveChemical & pharmaceutical bulletin2007
Mukai J, Tokuyama E, Ishizaka T, et al.
Branched-chain Amino Acid Biosensing Using Fluorescent Modified Engineered Leucine/Isoleucine/Valine Binding ProteinOther primary literatureUnknownUnknownInternational journal of molecular sciences2007
Chino S, Sakaguchi A, Yamoto R, et al.
[Effect of branched-chain amino acid-rich parenteral nutrition on protein metabolism after partial hepatectomy in rats with liver cirrhosis].Other primary literatureAnimalActiveNan fang yi ke da xue xue bao = Journal of Southern Medical University2007
Cao J, Luo SM, Liang LJ, et al.
A branched-chain amino acid aminotransferase gene isolated from Hordeum vulgare is differentially regulated by drought stress.Other primary literatureUnknownActiveTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2006
Malatrasi M, Corradi M, Svensson JT, et al.
Branched-chain amino acid supplementation complements conventional treatment for spontaneous bacterial peritonitis.Other primary literatureHumanActiveDigestive diseases and sciences2006
Taniguchi E, Kawaguchi T, Shimada M, et al.
Overweight and obesity increase the risk for liver cancer in patients with liver cirrhosis and long-term oral supplementation with branched-chain amino acid granules inhibits liver carcinogenesis in heavier patients with liver cirrhosis.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2006
Muto Y, Sato S, Watanabe A, et al.
Clofibrate treatment promotes branched-chain amino acid catabolism and decreases the phosphorylation state of mTOR, eIF4E-BP1, and S6K1 in rat liver.Other primary literatureAnimalActiveLife sciences2006
Ishiguro H, Katano Y, Nakano I, et al.
[Acrodermatitis enteropathica-like syndrome secondary to branched-chain amino acid deficiency during treatment of maple syrup urine disease].Other primary literatureHumanActiveAnnales de dermatologie et de venereologie2006
Templier I, Reymond JL, Nguyen MA, et al.
Nitrogen assimilation studies using 15N in soybean plants treated with imazethapyr, an inhibitor of branched-chain amino acid biosynthesis.Other primary literatureUnknownActiveJournal of agricultural and food chemistry2006
Zabalza A, Gaston S, Ribas-Carbó M, et al.
Dietary branched-chain amino acid valine, isoleucine and leucine requirements of fingerling Indian major carp, Cirrhinus mrigala (Hamilton).Other primary literatureAnimalActiveThe British journal of nutrition2006
Ahmed I, Khan MA
Influence of branched-chain amino acid supplementation on urinary protein metabolite concentrations after swimming.Randomized controlled trialHumanActiveJournal of the American College of Nutrition2006
Tang FC
Weight loss during prolonged branched-chain amino acid treatment for tardive dyskinesia in a patient with schizophrenia.Other primary literatureHumanActiveThe Australian and New Zealand journal of psychiatry2006
Gordon-Elliott JS, Margolese HC
Branched-chain amino acid needs in children with mild-to-moderate chronic cholestatic liver disease.Randomized controlled trialHumanActiveThe Journal of nutrition2006
Mager DR, Wykes LJ, Roberts EA, et al.
Lessons from genetic disorders of branched-chain amino acid metabolism.ReviewHuman & animalActiveThe Journal of nutrition2006
Chuang DT, Chuang JL, Wynn RM
Branched-chain amino acid catabolism in exercise and liver disease.ReviewHuman & animalActiveThe Journal of nutrition2006
Shimomura Y, Honda T, Shiraki M, et al.
Branched-chain amino acid requirements in healthy adult human subjects.ReviewHumanActiveThe Journal of nutrition2006
Kurpad AV, Regan MM, Raj T, et al.
Branched-chain amino acid enriched supplements as therapy for liver disease.ReviewHumanActiveThe Journal of nutrition2006
Charlton M
Branched-chain amino acid-enriched nutritional support in surgical and cancer patients.ReviewHumanActiveThe Journal of nutrition2006
Choudry HA, Pan M, Karinch AM, et al.
Assessment of branched-chain amino Acid status and potential for biomarkers.ReviewHumanActiveThe Journal of nutrition2006
Tom A, Nair KS
The female-specific Cs-ACS1G gene of cucumber. A case of gene duplication and recombination between the non-sex-specific 1-aminocyclopropane-1-carboxylate synthase gene and a branched-chain amino acid transaminase gene.Other primary literatureUnknownActivePlant & cell physiology2006
Knopf RR, Trebitsh T
The effect of increased branched-chain amino acid transaminase activity in yeast on the production of higher alcohols and on the flavour profiles of wine and distillates.Other primary literatureUnknownActiveFEMS yeast research2006
Lilly M, Bauer FF, Styger G, et al.
A subset of Actinobacillus pleuropneumoniae in vivo induced promoters respond to branched-chain amino acid limitation.Other primary literatureAnimalActiveFEMS immunology and medical microbiology2006
Wagner TK, Mulks MH
Identification and functional characterization of the Lactococcus lactis CodY-regulated branched-chain amino acid permease BcaP (CtrA).Other primary literatureUnknownActiveJournal of bacteriology2006
den Hengst CD, Groeneveld M, Kuipers OP, et al.
Simultaneous infusion of glutamine and branched-chain amino acids (BCAA) to septic rats does not have more favorable effect on protein synthesis in muscle, liver, and small intestine than separate infusions.Other primary literatureAnimalActiveJPEN. Journal of parenteral and enteral nutrition2006
Holecek M, Muthny T, Kovarik M, et al.
Effect of orthotopic liver transplantation (OLT) on branched-chain amino acid requirement.Other primary literatureHumanActivePediatric research2006
Mager DR, Wykes LJ, Roberts EA, et al.
Bitterness suppression of BCAA solutions by L-ornithine.Other primary literatureHumanActiveChemical & pharmaceutical bulletin2006
Tokuyama E, Shibasaki T, Kawabe H, et al.
The effects of a branched chain amino acid mixture supplemented with tryptophan on biochemical indices of neurotransmitter function and decision-making.Randomized controlled trialHumanActivePsychopharmacology2005
Scarnà A, McTavish SF, Cowen PJ, et al.
Branched-chain fatty acid biosynthesis in a branched-chain amino acid aminotransferase mutant of Staphylococcus carnosus.Other primary literatureUnknownActiveFEMS microbiology letters2005
Beck HC
Clinical comparison of branched-chain amino acid (l-Leucine, l-Isoleucine, l-Valine) granules and oral nutrition for hepatic insufficiency in patients with decompensated liver cirrhosis (LIV-EN study).Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2005
Sato S, Watanabe A, Muto Y, et al.
Effect of oral branched chain amino acid-rich nutrient administered during endoscopic injection sclerotherapy of cirrhotic patients.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2005
Katsumi N, Kawamura N, Yamaguchi Y, et al.
Usefulness of granular BCAA after hepatectomy for liver cancer complicated with liver cirrhosis.Randomized controlled trialHumanActiveNutrition (Burbank, Los Angeles County, Calif.)2005
Togo S, Tanaka K, Morioka D, et al.
Effects of oral branched-chain amino acid granules on event-free survival in patients with liver cirrhosis.Randomized controlled trialHumanActiveClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2005
Muto Y, Sato S, Watanabe A, et al.
Branched chain amino acid supplements in liver disease.Other primary literatureHumanActiveClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2005
Ghanta RK, Salvino RM, Mullen KD
Fermentative metabolism is induced by inhibiting different enzymes of the branched-chain amino acid biosynthesis pathway in pea plants.Other primary literatureUnknownActiveJournal of agricultural and food chemistry2005
Zabalza A, González EM, Arrese-Igor C, et al.
A mathematical model for the branched chain amino acid biosynthetic pathways of Escherichia coli K12.Other primary literatureUnknownActiveThe Journal of biological chemistry2005
Yang CR, Shapiro BE, Hung SP, et al.
Overview of the molecular and biochemical basis of branched-chain amino acid catabolism.ReviewHuman & animalActiveThe Journal of nutrition2005
Harris RA, Joshi M, Jeoung NH, et al.
Observations of branched-chain amino acid administration in humans.ReviewHuman & animalActiveThe Journal of nutrition2005
Matthews DE
Branched-chain amino acid supplementation in patients with liver diseases.ReviewHumanActiveThe Journal of nutrition2005
Marchesini G, Marzocchi R, Noia M, et al.
Update on branched-chain amino acid supplementation in liver diseases.ReviewHumanActiveCurrent opinion in gastroenterology2005
Bianchi G, Marzocchi R, Agostini F, et al.
Homocysteine toxicity in Escherichia coli is caused by a perturbation of branched-chain amino acid biosynthesis.Other primary literatureUnknownActiveJournal of bacteriology2005
Tuite NL, Fraser KR, O'byrne CP
The bkdR gene of Streptomyces coelicolor is required for morphogenesis and antibiotic production and encodes a transcriptional regulator of a branched-chain amino acid dehydrogenase complex.Other primary literatureUnknownActiveJournal of bacteriology2005
Sprusansky O, Stirrett K, Skinner D, et al.
Effects of dietary supplementation with branched-chain amino acids (BCAAs) during nursing on plasma BCAA levels and subsequent growth in cattle.Other primary literatureUnknownUnknownAsian-Australasian Journal of Animal Sciences2005
Li JY, Suzuki K, Koike Y, et al.
[Usefulness of branched-chain amino acid (BCAA)-enriched nutrient mixture for nutritional treatment undergoing endoscopic treatment for esophageal varices].Other primary literatureHumanActiveNihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology2005
Shibata N, Matsui H, Takeshita E, et al.
The effect of acute branched-chain amino acid supplementation on prolonged exercise capacity in a warm environment.Other primary literatureHumanActiveEuropean journal of applied physiology2004
Watson P, Shirreffs SM, Maughan RJ
Effects of liver failure on the enzymes in the branched-chain amino acid catabolic pathway.ReviewHuman & animalActiveBiochemical and biophysical research communications2004
Shimomura Y, Honda T, Goto H, et al.
Mechanisms responsible for regulation of branched-chain amino acid catabolism.ReviewHuman & animalActiveBiochemical and biophysical research communications2004
Harris RA, Joshi M, Jeoung NH
The utilization of the Antarctic environmental specimen bank (BCAA) in monitoring Cd and Hg in an Antarctic coastal area in Terra Nova Bay (Ross Sea--Northern Victoria Land).Other primary literatureAnimalActiveChemosphere2004
Riva SD, Abelmoschi ML, Magi E, et al.
Branched-chain amino acid treatment in patients with liver cirrhosis.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2004
Suzuki K, Kato A, Iwai M
How to select BCAA preparations.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2004
Kato A, Suzuki K
Effect of oral supplementation with branched-chain amino acid granules in the early stage of cirrhosis.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2004
Nishiguchi S, Habu D
Regulation of branched-chain amino acid metabolism and pharmacological effects of branched-chain amino acids.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2004
Shimomura Y, Murakami T, Nagasaki M, et al.
Administration of granulated BCAA and quality of life.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2004
Kawamura N, Nakajima H, Takashi SI
Leucine toxicity in a neuronal cell model with inhibited branched chain amino acid catabolism.Other primary literatureAnimalActiveBrain research. Molecular brain research2004
Kasinski A, Doering CB, Danner DJ
Effect of alternative pathway therapy on branched chain amino acid metabolism in urea cycle disorder patients.Other primary literatureHumanActiveMolecular genetics and metabolism2004
Scaglia F, Carter S, O'Brien WE, et al.
The effects of standard and branched chain amino acid enriched solutions on thermogenesis and energy expenditure in unconscious intensive care patients.Randomized controlled trialHumanActiveClinical nutrition (Edinburgh, Scotland)2004
Cankayali I, Demirag K, Kocabas S, et al.
Estrogen controls branched-chain amino acid catabolism in female rats.Other primary literatureAnimalActiveThe Journal of nutrition2004
Obayashi M, Shimomura Y, Nakai N, et al.
Exercise promotes BCAA catabolism: effects of BCAA supplementation on skeletal muscle during exercise.ReviewHuman & animalActiveThe Journal of nutrition2004
Shimomura Y, Murakami T, Nakai N, et al.
Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis.Other primary literatureUnknownActivePlant physiology2004
Taylor NL, Heazlewood JL, Day DA, et al.
Purification and characterization of a branched-chain amino acid aminotransferase from Lactobacillus paracasei subsp. paracasei CHCC 2115.Other primary literatureUnknownActiveJournal of applied microbiology2004
Thage BV, Rattray FP, Laustsen MW, et al.
New support for branched-chain amino acid supplementation in advanced hepatic failure.ReviewHumanActiveNutrition reviews2004
Mascarenhas R, Mobarhan S
Transcriptional organization and posttranscriptional regulation of the Bacillus subtilis branched-chain amino acid biosynthesis genes.Other primary literatureUnknownActiveJournal of bacteriology2004
Mäder U, Hennig S, Hecker M, et al.
Branched-chain amino acid catabolism: unique segregation of pathway enzymes in organ systems and peripheral nerves.Other primary literatureAnimalActiveAmerican journal of physiology. Endocrinology and metabolism2004
Sweatt AJ, Wood M, Suryawan A, et al.
Branched-chain amino acid supplementation and human performance when hypohydrated in the heat.Other primary literatureHumanActiveJournal of applied physiology (Bethesda, Md. : 1985)2004
Cheuvront SN, Carter R 3rd, Kolka MA, et al.
Branched-chain amino acid aminotransferase and methionine formation in Mycobacterium tuberculosis.Other primary literatureUnknownActiveBMC microbiology2004
Venos ES, Knodel MH, Radford CL, et al.
Branched chain amino acid treatment of tardive dyskinesia in children and adolescents.Other primary literatureHumanActiveThe Journal of clinical psychiatry2004
Richardson MA, Small AM, Read LL, et al.
Mitochondria-derived glutamate at the interplay between branched-chain amino acid and glucose-induced insulin secretion.Other primary literatureAnimalActiveFEBS letters2003
Broca C, Brennan L, Petit P, et al.
Branched-chain amino acid-enriched supplements as therapy for liver disease: Rasputin lives.Other primary literatureHumanActiveGastroenterology2003
Charlton M
Effect of oral supplementation with branched-chain amino acid granules on serum albumin level in the early stage of cirrhosis: a randomized pilot trial.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2003
Habu D, Nishiguchi S, Nakatani S, et al.
Relationship between branched-chain amino acid to tyrosine ratio (BTR) and porto-systemic shunt in the Child-Pugh grade A cirrhosis determined by per-rectal portal scintigraphy.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2003
Habu D, Nishiguchi S, Nakatani S, et al.
Crystal structures of branched-chain amino acid aminotransferase complexed with glutamate and glutarate: true reaction intermediate and double substrate recognition of the enzyme.Other primary literatureUnknownActiveBiochemistry2003
Goto M, Miyahara I, Hayashi H, et al.
A double-blind randomized clinical trial in amyotrophic lateral sclerosis using lamotrigine: effects on CSF glutamate, aspartate, branched-chain amino acid levels and clinical parameters.Randomized controlled trialHumanActiveActa neurologica Scandinavica2003
Ryberg H, Askmark H, Persson LI
Regulation of branched-chain amino acid biosynthesis by alpha-acetolactate decarboxylase in Streptococcus thermophilus.Other primary literatureUnknownActiveLetters in applied microbiology2003
Monnet C, Nardi M, Hols P, et al.
Valine may be the first limiting branched-chain amino acid in egg protein in men.Other primary literatureHumanActiveThe Journal of nutrition2003
Riazi R, Rafii M, Wykes LJ, et al.
Branched-chain amino acid requirements in school-aged children determined by indicator amino acid oxidation (IAAO).Other primary literatureHumanActiveThe Journal of nutrition2003
Mager DR, Wykes LJ, Ball RO, et al.
The total branched-chain amino acid requirement in young healthy adult men determined by indicator amino acid oxidation by use of L-[1-13C]phenylalanine.Other primary literatureHumanActiveThe Journal of nutrition2003
Riazi R, Wykes LJ, Ball RO, et al.
Improvement of regional cerebral blood flow after treatment with branched-chain amino acid solutions in patients with cirrhosis.Other primary literatureHumanActiveEuropean journal of gastroenterology & hepatology2003
Iwasa M, Matsumura K, Watanabe Y, et al.
Changes in mitochondrial electron partitioning in response to herbicides inhibiting branched-chain amino acid biosynthesis in soybean.Other primary literatureUnknownActivePlant physiology2003
Gaston S, Ribas-Carbo M, Busquets S, et al.
Branched-chain amino acid supplementation during bed rest: effect on recovery.Other primary literatureHumanActiveJournal of applied physiology (Bethesda, Md. : 1985)2003
Stein TP, Donaldson MR, Leskiw MJ, et al.
Nocturnal branched-chain amino acid administration improves protein metabolism in patients with liver cirrhosis: comparison with daytime administration.Randomized controlled trialHumanActiveJPEN. Journal of parenteral and enteral nutrition2003
Fukushima H, Miwa Y, Ida E, et al.
Effects of a branched-chain amino acid drink in mania.Randomized controlled trialHumanActiveThe British journal of psychiatry : the journal of mental science2003
Scarna A, Gijsman HJ, McTavish SF, et al.
The effects of the formula of amino acids enriched BCAA on nutritional support in traumatic patients.Randomized controlled trialHumanActiveWorld journal of gastroenterology2003
Wang XY, Li N, Gu J, et al.
A continuous 96-well plate spectrophotometric assay for branched-chain amino acid aminotransferases.Other primary literatureHuman & animalActiveAnalytical biochemistry2002
Cooper AJ, Conway M, Hutson SM
Clofibric acid stimulates branched-chain amino acid catabolism by three mechanisms.Other primary literatureAnimalActiveArchives of biochemistry and biophysics2002
Kobayashi R, Murakami T, Obayashi M, et al.
Double-blind crossover study of branched-chain amino acid therapy in patients with spinocerebellar degeneration.Other primary literatureHumanActiveJournal of the neurological sciences2002
Mori M, Adachi Y, Mori N, et al.
Branched-chain amino acid supplementation and the immune response of long-distance athletes.Other primary literatureHumanActiveNutrition (Burbank, Los Angeles County, Calif.)2002
Bassit RA, Sawada LA, Bacurau RF, et al.
Clinical and neuroradiological improvement in chronic acquired hepatocerebral degeneration after branched-chain amino acid therapy.Other primary literatureHumanActiveActa neurologica Scandinavica2002
Ueki Y, Isozaki E, Miyazaki Y, et al.
The branched-chain amino acid requirement of parenterally fed neonatal piglets is less than the enteral requirement.Other primary literatureAnimalActiveThe Journal of nutrition2002
Elango R, Pencharz PB, Ball RO
The branched-chain amino acid transaminase gene family in Arabidopsis encodes plastid and mitochondrial proteins.Other primary literatureUnknownActivePlant physiology2002
Diebold R, Schuster J, Däschner K, et al.
Effect of bacteriocin-induced cell damage on the branched-chain amino acid transamination by Lactococcus lactis.Other primary literatureUnknownActiveFEMS microbiology letters2002
Martínez-Cuesta C, Requena T, Peláez C
Equine endurance exercise alters serum branched-chain amino acid and alanine concentrations.Other primary literatureAnimalActiveEquine veterinary journal. Supplement2002
Trottier NL, Nielsen BD, Lang KJ, et al.
A mutant of Burkholderia pseudomallei, auxotrophic in the branched chain amino acid biosynthetic pathway, is attenuated and protective in a murine model of melioidosis.Other primary literatureAnimalActiveInfection and immunity2002
Atkins T, Prior RG, Mack K, et al.
Rhizobium leguminosarum has a second general amino acid permease with unusually broad substrate specificity and high similarity to branched-chain amino acid transporters (Bra/LIV) of the ABC family.Other primary literatureUnknownActiveJournal of bacteriology2002
Hosie AH, Allaway D, Galloway CS, et al.
Insufficient expression of the ilv-leu operon encoding enzymes of branched-chain amino acid biosynthesis limits growth of a Bacillus subtilis ccpA mutant.Other primary literatureUnknownActiveJournal of bacteriology2002
Ludwig H, Meinken C, Matin A, et al.
Isolation and purification of polysaccharide from the pumpkin and studies of its decrease BCAA activityDesign not determinedUnknownUnknownJournal of Jining Medical College2002
Kong Qingsheng, Jiang Ying
Involvement of branched-chain amino acid aminotransferases in the production of fusel alcohols during fermentation in yeast.Other primary literatureUnknownActiveApplied microbiology and biotechnology2001
Eden A, Van Nedervelde L, Drukker M, et al.
Plasma lactate, GH and GH-binding protein levels in exercise following BCAA supplementation in athletes.Other primary literatureHumanActiveAmino acids2001
De Palo EF, Gatti R, Cappellin E, et al.
Leucine and its keto acid enhance the coordinated expression of genes for branched-chain amino acid catabolism in Arabidopsis under sugar starvation.Other primary literatureUnknownActiveFEBS letters2001
Fujiki Y, Ito M, Nishida I, et al.
The BCAA-BCKA cycle: its relation to alanine and glutamine synthesis and protein balance.Other primary literatureHumanActiveNutrition (Burbank, Los Angeles County, Calif.)2001
Holecek M
Effect of oral branched chain amino acid supplementation in the late evening on the nutritional state of patients with liver cirrhosis.Other primary literatureUnknownActiveHepatology research : the official journal of the Japan Society of Hepatology2001
Yamauchi M, Takeda K, Sakamoto K, et al.
Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme.Other primary literatureUnknownActiveBiochemistry2001
Okada K, Hirotsu K, Hayashi H, et al.
Evidence that the branched-chain amino acid L-valine prevents exercise-induced release of 5-HT in rat hippocampus.Other primary literatureAnimalActiveInternational journal of sports medicine2001
Gomez-Merino D, Béquet F, Berthelot M, et al.
Molecular mechanisms in the brain involved in the anorexia of branched-chain amino acid deficiency.ReviewAnimalActiveThe Journal of nutrition2001
Gietzen DW, Magrum LJ
Branched-chain amino acid aminotransferase activity decreases during development in skeletal muscles of sheep.Other primary literatureAnimalActiveThe Journal of nutrition2001
Faure M, Glomot F, Papet I
Oral supplementation of branched-chain amino acid improves nutritional status in elderly patients on chronic haemodialysis.Randomized controlled trialHumanActiveNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2001
Hiroshige K, Sonta T, Suda T, et al.
Regulation of branched-chain amino acid catabolism: nutritional and hormonal regulation of activity and expression of the branched-chain alpha-keto acid dehydrogenase kinase.ReviewHumanActiveCurrent opinion in clinical nutrition and metabolic care2001
Shimomura Y, Obayashi M, Murakami T, et al.
The basal turnover of yeast branched-chain amino acid permease Bap2p requires its C-terminal tail.Other primary literatureUnknownActiveFEMS microbiology letters2001
Omura F, Kodama Y, Ashikari T
Isolation and characterization of a gene specific to lager brewing yeast that encodes a branched-chain amino acid permease.Other primary literatureUnknownActiveApplied and environmental microbiology2001
Kodama Y, Omura F, Ashikari T
Comparison of DeltarelA strains of Escherichia coli and Salmonella enterica serovar Typhimurium suggests a role for ppGpp in attenuation regulation of branched-chain amino acid biosynthesis.Other primary literatureUnknownActiveJournal of bacteriology2001
Tedin K, Norel F
BCAA intake affects protein metabolism in muscle after but not during exercise in humans.Other primary literatureHumanActiveAmerican journal of physiology. Endocrinology and metabolism2001
Blomstrand E, Saltin B
Distribution of key enzymes of branched-chain amino acid metabolism in glial and neuronal cells in culture.Other primary literatureAnimalActiveThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society2001
Bixel M, Shimomura Y, Hutson S, et al.
Uteroplacental insufficiency alters liver and skeletal muscle branched-chain amino acid metabolism in intrauterine growth-restricted fetal rats.Other primary literatureAnimalActivePediatric research2001
Kloesz JL, Serdikoff CM, Maclennan NK, et al.
Effect of branched Chain amino acid on protein metabolism in exercised rats and miceDesign not determinedUnknownUnknown[Ying yang xue bao] Acta nutrimenta Sinica2001
Xu Zhiqin, Sun Yongmei, Jin Hong, et al.
[Oral supplement of BCAA in patients with liver disease].ReviewHumanActiveNihon rinsho. Japanese journal of clinical medicine2001
Yoshida S, Ishibashi N, Tajiri T, et al.
Controlled overexpression of BCKD kinase expression: metabolic engineering applied to BCAA metabolism in a mammalian system.Other primary literatureAnimalActiveMetabolic engineering2000
Doering CB, Williams IR, Danner DJ
Analysis of intracellular metabolites as tool for studying branched-chain amino acid biosynthesis and its inhibition in bacteria.Other primary literatureUnknownActiveMethods in enzymology2000
Epelbaum S, Chipman DM, Barak Z
Detection of gene defects in branched-chain amino acid metabolism by tandem mass spectrometry of carnitine esters produced by cultured fibroblasts.Other primary literatureHumanActiveMethods in enzymology2000
Roe CR, Roe DS
Molecular and enzymatic methods for detection of genetic defects in distal pathways of branched-chain amino acid metabolism.Other primary literatureHumanActiveMethods in enzymology2000
Gibson KM, Ugarte M, Fukao T, et al.
Serotonergic markers and lowered plasma branched-chain-amino acid concentrations in fibromyalgia.Other primary literatureHumanActivePsychiatry research2000
Maes M, Verkerk R, Delmeire L, et al.
Sheep cytosolic branched-chain amino acid aminotransferase: cDNA cloning, primary structure and molecular modelling and its unique expression in muscles.Other primary literatureAnimalActiveBiochimica et biophysica acta2000
Bonfils J, Faure M, Gibrat JF, et al.
Branched-chain amino acid-enriched diet: effects on insulin secretion and cellular immune aggression.Other primary literatureAnimalActiveProceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)2000
Karabatas LM, De Bruno LF, Pastorale C, et al.
The effect of BCAA supplementation upon the immune response of triathletes.Other primary literatureHumanActiveMedicine and science in sports and exercise2000
Bassit RA, Sawada LA, Bacurau RF, et al.
Branched-chain amino acid biosynthesis is essential for optimal growth of Streptococcus thermophilus in milk.Other primary literatureAnimalActiveApplied and environmental microbiology2000
Garault P, Letort C, Juillard V, et al.
Effects of branched-chain amino acid supplementation on serum creatine kinase and lactate dehydrogenase after prolonged exercise.Other primary literatureHumanActiveThe Journal of sports medicine and physical fitness2000
Coombes JS, McNaughton LR
Evaluating response to nutritional therapy using the branched-chain amino acid/tyrosine ratio in patients with chronic liver disease.Other primary literatureHumanActiveJournal of clinical laboratory analysis1999
Kawamura-Yasui N, Kaito M, Nakagawa N, et al.
Ratio of branched chain amino acid to tyrosine after hepatectomy.Other primary literatureHumanActiveSurgery today1999
Niguma T, Yumura M, Yamasita Y, et al.
Involvement of branched-chain amino acid aminotransferase (Bcat1/Eca39) in apoptosis.Other primary literatureAnimalActiveFEBS letters1999
Eden A, Benvenisty N
Phospholipids stabilize the secondary structure of the sodium-coupled branched-chain amino acid carrier of Pseudomonas aeruginosa.Other primary literatureUnknownActiveBiochimica et biophysica acta1999
Uratani Y, Kobayashi M, Yokoyama Y, et al.
Abnormalities in branched-chain amino acid metabolism in cirrhosis: influence of hormonal and nutritional factors and directions for future research.ReviewHumanActiveClinical nutrition (Edinburgh, Scotland)1999
Blonde-Cynober F, Aussel C, Cynober L
Branched-chain amino acid-induced hippocampal norepinephrine release is antagonized by picrotoxin: evidence for a central mode of action.Other primary literatureAnimalActiveBrain research bulletin1999
Torigoe K, Potter PE, Katz DP
Cloning of branched chain amino acid biosynthesis genes and assays of alpha-acetolactate synthase activities in Leuconostoc mesenteroides subsp. cremoris.Other primary literatureUnknownActiveResearch in microbiology1999
Cavin JF, Dartois V, Labarre C, et al.
Effects of a branched-chain amino acid-enriched diet on chronic hepatic encephalopathy in dogs.Other primary literatureAnimalActiveMetabolic brain disease1999
Meyer HP, Chamuleau RA, Legemate DA, et al.
Purification and cloning of the mitochondrial branched-chain amino acid aminotransferase from sheep placenta.Other primary literatureAnimalActiveEuropean journal of biochemistry1999
Faure M, Glomot F, Bledsoe R, et al.
Effect of branched-chain amino acids (BCAA), glucose, and glucose plus BCAA on endurance performance in rats.Other primary literatureAnimalActiveMedicine and science in sports and exercise1999
Calders P, Matthys D, Derave W, et al.
End-product control of expression of branched-chain amino acid biosynthesis genes in Streptomyces coelicolor A3(2): paradoxical relationships between DNA sequence and regulatory phenotype.Other primary literatureUnknownActiveMicrobiology (Reading, England)1999
Craster HL, Potter CA, Baumberg S
Low glycogen and branched-chain amino acid ingestion do not impair anaplerosis during exercise in humans.Other primary literatureHumanActiveJournal of applied physiology (Bethesda, Md. : 1985)1999
Gibala MJ, Lozej M, Tarnopolsky MA, et al.
Branched-chain amino acid therapy for spinocerebellar degeneration: a pilot clinical crossover trial.Randomized controlled trialHumanActiveInternal medicine (Tokyo, Japan)1999
Mori N, Adachi Y, Takeshima T, et al.
The effects of branched chain amino acid infusion on pain perception and plasma concentrations of monoamines.Randomized controlled trialHumanActivePharmacology, biochemistry, and behavior1998
Kirvelä O, Jaatinen J, Scheinin H, et al.
Kinetic studies of the branched chain amino acid preferring peptidase activity of the 20S proteasome: development of a continuous assay and inhibition by tripeptide aldehydes and clasto-lactacystin beta-lactone.Other primary literatureAnimalActiveBiochemistry1998
McCormack TA, Cruikshank AA, Grenier L, et al.
Altered properties of the branched chain amino acid-preferring activity contribute to increased cleavages after branched chain residues by the "immunoproteasome".Other primary literatureAnimalActiveThe Journal of biological chemistry1998
Cardozo C, Kohanski RA
A molecular model of human branched-chain amino acid metabolism.Other primary literatureHuman & animalActiveThe American journal of clinical nutrition1998
Suryawan A, Hawes JW, Harris RA, et al.
Inhibitors of branched-chain amino acid biosynthesis as potential antituberculosis agents.Other primary literatureAnimalActiveThe Journal of antimicrobial chemotherapy1998
Grandoni JA, Marta PT, Schloss JV
Regulation of branched-chain amino acid metabolism in the lactating rat.Other primary literatureAnimalActiveThe Journal of nutrition1998
DeSantiago S, Torres N, Suryawan A, et al.
Sexual differences in branched chain amino acid metabolism into fatty acids and cholesterol in Harderian gland of golden hamster.Other primary literatureAnimalActiveJournal of biochemistry1998
Hida A, Uchijima Y, Seyama Y
Overtraining and the BCAA hypothesis.ReviewHuman & animalActiveMedicine and science in sports and exercise1998
Gastmann UA, Lehmann MJ
Influence of alcohol on branched-chain amino acid/tyrosine molar ratio in patients with cirrhosis.Other primary literatureHumanActiveAlcoholism, clinical and experimental research1998
Suzuki H, Mamata Y, Mizuno H, et al.
Branched-chain amino acid biosynthesis in Salmonella typhimurium: a quantitative analysis.Other primary literatureUnknownActiveJournal of bacteriology1998
Epelbaum S, LaRossa RA, VanDyk TK, et al.
Constricted flux through the branched-chain amino acid biosynthetic enzyme acetolactate synthase triggers elevated expression of genes regulated by rpoS and internal acidification.Other primary literatureUnknownActiveJournal of bacteriology1998
Van Dyk TK, Ayers BL, Morgan RW, et al.
Effect of branched chain amino acid supplementation on energy substrate metabolism in exercised rat myocardiumDesign not determinedUnknownUnknown[Ying yang xue bao] Acta nutrimenta Sinica1998
Zhao Wenxing, Gao Lanxing, Wang Xianyuan, et al.
A branched chain amino acid-enriched solution does not induce any beneficial effect on the postoperative intestinal functions.Randomized controlled trialHumanActiveHepato-gastroenterology1998
Shimada M, Hasegawa H, Gion T, et al.
Effects of branched-chain amino acid-enriched nutrient mixture on natural killer cell activity in viral cirrhosis.Other primary literatureHumanActiveArzneimittel-Forschung1998
Takegoshi K, Nanasawa H, Itoh H, et al.
[Branched chain amino acid diseases].ReviewHumanActiveActa medica portuguesa1998
Cabral A, Portela R, Tasso T, et al.
The branched-chain amino acid permease gene of Saccharomyces cerevisiae, BAP2, encodes the high-affinity leucine permease (S1).Other primary literatureUnknownActiveYeast (Chichester, England)1997
Schreve J, Garrett JM
Gender difference in regulation of branched-chain amino acid catabolism.Other primary literatureAnimalActiveThe Biochemical journal1997
Kobayashi R, Shimomura Y, Murakami T, et al.
Combined effects of caloric restriction and branched-chain amino acid supplementation on body composition and exercise performance in elite wrestlers.Other primary literatureHumanActiveInternational journal of sports medicine1997
Mourier A, Bigard AX, de Kerviler E, et al.
Changes in plasma tryptophan/branched chain amino acid ratio in responses to training volume variation.Other primary literatureHumanActiveInternational journal of sports medicine1997
Tanaka H, West KA, Duncan GE, et al.
Three-dimensional structure of Escherichia coli branched-chain amino acid aminotransferase at 2.5 A resolution.Other primary literatureUnknownActiveJournal of biochemistry1997
Okada K, Hirotsu K, Sato M, et al.
Alanylglutamine-enriched total parenteral nutrition improves protein metabolism more than branched chain amino acid-enriched total parenteral nutrition in protracted peritonitis.Other primary literatureAnimalActiveThe Journal of trauma1997
Naka S, Saito H, Hashiguchi Y, et al.
Pre-exercise branched-chain amino acid administration increases endurance performance in rats.Other primary literatureAnimalActiveMedicine and science in sports and exercise1997
Calders P, Pannier JL, Matthys DM, et al.
An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport.Other primary literatureUnknownActiveJournal of bacteriology1997
Belitsky BR, Gustafsson MC, Sonenshein AL, et al.
Cellular distribution of branched-chain amino acid aminotransferase isoenzymes among rat brain glial cells in culture.Other primary literatureAnimalActiveThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society1997
Bixel MG, Hutson SM, Hamprecht B
Mobilization of visceral adipose tissue related to the improvement in insulin sensitivity in response to physical training in NIDDM. Effects of branched-chain amino acid supplements.Randomized controlled trialHumanActiveDiabetes care1997
Mourier A, Gautier JF, De Kerviler E, et al.
[Amino acid metabolism in alcoholics: plasma branched-chain amino acid/aromatic amino acid molar ratio in alcoholics].ReviewHumanActiveNihon rinsho. Japanese journal of clinical medicine1997
Saito T
Branched-chain amino acid catabolism in uremia: dual regulation of branched-chain alpha-ketoacid dehydrogenase by extracellular pH and glucocorticoids.ReviewHuman & animalActiveMineral and electrolyte metabolism1997
Wang X, Jurkovitz C, Price SR
Cleavage of Pro-X and Glu-X bonds catalyzed by the branched chain amino acid preferring activity of the bovine pituitary multicatalytic proteinase complex (20S proteasome).Other primary literatureAnimalActiveArchives of biochemistry and biophysics1996
Cardozo C, Chen WE, Wilk S
Spectrophometric assay for measuring branched-chain amino acid concentrations: application for measuring the sensitivity of protein metabolism to insulin.Other primary literatureHumanActiveAnalytical biochemistry1996
Beckett PR, Hardin DS, Davis TA, et al.
The effect of branched-chain amino acid-enriched parenteral nutrition on gut permeability.Other primary literatureAnimalActiveNutrition (Burbank, Los Angeles County, Calif.)1996
McCauley R, Heel KA, Barker PR, et al.
Astrocyte leucine metabolism: significance of branched-chain amino acid transamination.Other primary literatureAnimalActiveJournal of neurochemistry1996
Yudkoff M, Daikhin Y, Grunstein L, et al.
Two yeast homologs of ECA39, a target for c-Myc regulation, code for cytosolic and mitochondrial branched-chain amino acid aminotransferases.Other primary literatureHuman & animalActiveThe Journal of biological chemistry1996
Eden A, Simchen G, Benvenisty N
Mitochondrial and cytosolic branched-chain amino acid transaminases from yeast, homologs of the myc oncogene-regulated Eca39 protein.Other primary literatureHumanActiveThe Journal of biological chemistry1996
Kispal G, Steiner H, Court DA, et al.
Effect of a 6-week endurance training programme and branched-chain amino acid supplementation on histomorphometric characteristics of aged human muscle.Other primary literatureHumanActiveArchives of physiology and biochemistry1996
Freyssenet D, Berthon P, Denis C, et al.
End-product control of enzymes of branched-chain amino acid biosynthesis in Streptomyces coelicolor.Other primary literatureUnknownActiveMicrobiology (Reading, England)1996
Potter CA, Baumberg S
Stimulation of muscle ammonia production during exercise following branched-chain amino acid supplementation in humans.Other primary literatureHumanActiveThe Journal of physiology1996
MacLean DA, Graham TE, Saltin B
Branched-chain amino acid supplementation during repeated prolonged skiing exercises at altitude.Other primary literatureHumanActiveInternational journal of sport nutrition1996
Bigard AX, Lavier P, Ullmann L, et al.
Metabolic effects of inhibitors of two enzymes of the branched-chain amino acid pathway in Salmonella typhimurium.Other primary literatureUnknownActiveJournal of bacteriology1996
Epelbaum S, Chipman DM, Barak Z
Amino acids induce expression of BAP2, a branched-chain amino acid permease gene in Saccharomyces cerevisiae.Other primary literatureUnknownActiveJournal of bacteriology1996
Didion T, Grauslund M, Kielland-Brandt MC, et al.
Overview of randomized clinical trials of oral branched-chain amino acid treatment in chronic hepatic encephalopathy.ReviewHumanActiveJPEN. Journal of parenteral and enteral nutrition1996
Fabbri A, Magrini N, Bianchi G, et al.
Branched-chain amino acid catabolism and cancer cachexia (review).Other primary literatureUnknownActiveOncology reports1996
Argiles J, Costelli P, Carbo N, et al.
Acidosis and glucocorticoids induce branched-chain amino acid catabolism.ReviewHuman & animalActiveMineral and electrolyte metabolism1996
England BK, Grewal M, Bailey JL, et al.
Effects of branched-chain amino acid infusion on protein metabolism in rats with acute hepatic failure.Other primary literatureAnimalActiveHepatology (Baltimore, Md.)1995
Miwa Y, Kato M, Moriwaki H, et al.
An enzyme in yeast mitochondria that catalyzes a step in branched-chain amino acid biosynthesis also functions in mitochondrial DNA stability.Other primary literatureUnknownActiveThe EMBO journal1995
Zelenaya-Troitskaya O, Perlman PS, Butow RA
Enzymatic method for determination of branched-chain amino acid aminotransferase activity.Other primary literatureAnimalActiveAnalytical biochemistry1995
Schadewaldt P, Hummel W, Wendel U, et al.
Cloning and characterization of brnQ, a gene encoding a low-affinity, branched-chain amino acid carrier in Lactobacillus delbrückii subsp. lactis DSM7290.Other primary literatureUnknownActiveMolecular & general genetics : MGG1995
Stucky K, Hagting A, Klein JR, et al.
Overnight branched-chain amino acid infusion causes sustained suppression of muscle proteolysis.Other primary literatureHumanActiveMetabolism: clinical and experimental1995
Louard RJ, Barrett EJ, Gelfand RA
Regulation of expression of the valine (branched-chain amino acid) dehydrogenase-encoding gene from Streptomyces coelicolor.Other primary literatureUnknownActiveGene1995
Tang L, Hutchinson CR
Leucine affects the metabolism of valine by isolated perfused rat hearts: relation to branched-chain amino acid antagonism.Other primary literatureAnimalActiveThe Journal of nutrition1995
Torres N, Tovar AR, Harper AE
Effect of branched-chain amino acid and carbohydrate supplementation on the exercise-induced change in plasma and muscle concentration of amino acids in human subjects.Randomized controlled trialHumanActiveActa physiologica Scandinavica1995
Blomstrand E, Andersson S, Hassmén P, et al.
Purification and properties of branched chain amino acid aminotransferase from gramicidin S-producing Bacillus brevis.Other primary literatureUnknownActiveJournal of nutritional science and vitaminology1995
Kanda M, Hori K, Kurotsu T, et al.
Effects of branched-chain amino acids (BCAA) on protein metabolism in bedridden and tube-feeding patientsDesign not determinedUnknownUnknown[Ying yang xue bao] Acta nutrimenta Sinica1995
Xue Changyong, Wang Weiqing, Li Xiya, et al.
Clinical study of an enteral branched-chain amino acid solution in decompensated liver cirrhosis with hepatic encephalopathy.Other primary literatureHumanActiveNutrition (Burbank, Los Angeles County, Calif.)1995
Ichida T, Shibasaki K, Muto Y, et al.
Parenteral administration of amino acids in disorders of branched-chain amino acid metabolism.Other primary literatureHumanActiveJournal of inherited metabolic disease1994
Sperl W, Skladal D, Endres W, et al.
Effect of infusing branched-chain amino acid during incremental exercise with reduced muscle glycogen content.Randomized controlled trialHumanActiveEuropean journal of applied physiology and occupational physiology1994
Varnier M, Sarto P, Martines D, et al.
Screening for defects of branched-chain amino acid metabolism.ReviewHumanActiveEuropean journal of pediatrics1994
Gibson KM, Lee CF, Hoffmann GF
Tumor and host tissue responses to branched-chain amino acid supplementation of patients with cancer M A McNurlan, S D Heys, K G M Park et al Clinical Science 1994; 86: 339-345.Other primary literatureUnknownActiveClinical nutrition (Edinburgh, Scotland)1994
Le Bricon T
Postoperative enteral hyperalimentation results in earlier elevation of serum branched-chain amino acid levels.Other primary literatureHumanActiveAmerican journal of surgery1994
Moss G, Naylor ED
Tumour and host tissue responses to branched-chain amino acid supplementation of patients with cancer.Randomized controlled trialHumanActiveClinical science (London, England : 1979)1994
McNurlan MA, Heys SD, Park KG, et al.
Regulation of branched-chain amino acid catabolism.ReviewHuman & animalActiveThe Journal of nutrition1994
Harris RA, Popov KM, Zhao Y, et al.
Interaction between valproate and branched-chain amino acid metabolism.Other primary literatureHumanActiveNeurology1994
Anderson GD, Acheampong AA, Levy RH
Administration of a branched-chain amino acid preparation during hepatic failure: a study emphasizing ammonia metabolism.Other primary literatureHumanActiveActa medica Okayama1994
Nishikawa Y, Ukida M, Matsuo R, et al.
Branched-chain amino acid supplementation during 30-km competitive run: mood and cognitive performance.Randomized controlled trialHumanActiveNutrition (Burbank, Los Angeles County, Calif.)1994
Hassmén P, Blomstrand E, Ekblom B, et al.
Aromatic and branched-chain amino acid levels in alcoholics.Other primary literatureHumanActiveAlcohol and alcoholism (Oxford, Oxfordshire). Supplement1994
Saito T, Kobatake K, Ozawa H, et al.
Synthesis of alpha, beta-deuterated 15N amino acids using a coupled glutamate dehydrogenase-branched-chain amino acid aminotransferase system.Other primary literatureUnknownActiveAnalytical biochemistry1993
Chanatry JA, Schafer PH, Kim MS, et al.
Branched-chain amino acid supplementation during trekking at high altitude. The effects on loss of body mass, body composition and muscle power.Other primary literatureHumanActiveEuropean journal of applied physiology and occupational physiology1993
Wagenmakers AJ
A study of branched-chain amino acid aminotransferase and isolation of mutations affecting the catabolism of branched-chain amino acids in Saccharomyces cerevisiae.Other primary literatureUnknownActiveFEBS letters1993
Dickinson JR, Norte V
Alterations in mitochondrial branched-chain amino acid metabolism in brain in acute hyperammonemic states.Other primary literatureAnimalActiveNeuroscience letters1993
Alexander J, Murthy CR
Branched-chain amino acid transport in Streptococcus mutans Ingbritt.Other primary literatureUnknownActiveOral microbiology and immunology1993
Dashper SG, Reynolds EC
Sequence, transcriptional, and functional analyses of the valine (branched-chain amino acid) dehydrogenase gene of Streptomyces coelicolor.Other primary literatureUnknownActiveJournal of bacteriology1993
Tang L, Hutchinson CR
Gene inactivation in Lactococcus lactis: branched-chain amino acid biosynthesis.Other primary literatureUnknownActiveJournal of bacteriology1993
Godon JJ, Delorme C, Bardowski J, et al.
Branched-chain amino acid supplementation augments plasma ammonia responses during exercise in humans.Other primary literatureHumanActiveJournal of applied physiology (Bethesda, Md. : 1985)1993
MacLean DA, Graham TE
Organ transplantation and branched chain amino acid metabolism in humans: methodological problems and possible pitfalls.ReviewHumanActiveThe Italian journal of gastroenterology1993
Luzi L, Pozza G
[A case of liver cirrhosis with portal vein calcification associated with hypoglycemia induced by branched chain amino acid solution].Other primary literatureHumanActiveNihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology1993
Uemura K, Sakato M, Miyahara H, et al.
Regulation by insulin of branched chain amino acid metabolism in cirrhosis.Other primary literatureHumanActiveThe Italian journal of gastroenterology1993
Petrides AS
Tumor and host response to arginine and branched chain amino acid-enriched total parenteral nutrition. A study involving Walker 256 carcinosarcoma-bearing rats.Other primary literatureAnimalActiveCancer1992
Ye SL, Istfan NW, Driscoll DF, et al.
Branched-chain amino acid supplementation during trekking at high altitude. The effects on loss of body mass, body composition, and muscle power.Other primary literatureHumanActiveEuropean journal of applied physiology and occupational physiology1992
Schena F, Guerrini F, Tregnaghi P, et al.
Changes in the exercise-induced hormone response to branched chain amino acid administration.Other primary literatureHumanActiveEuropean journal of applied physiology and occupational physiology1992
Carli G, Bonifazi M, Lodi L, et al.
The enzymatic activities of branched-chain amino acid catabolism in tumour-bearing rats.Other primary literatureAnimalActiveCancer letters1992
Argilés JM, López-Soriano FJ
Immunoaffinity purification and reconstitution of sodium-coupled branched-chain amino acid carrier of Pseudomonas aeruginosa.Other primary literatureUnknownActiveThe Journal of biological chemistry1992
Uratani Y
Solubilization and reconstitution of the Pseudomonas aeruginosa high affinity branched-chain amino acid transport system.Other primary literatureUnknownActiveThe Journal of biological chemistry1992
Hoshino T, Kose-Terai K, Sato K
Nutritional support in children with end-stage liver disease: a randomized crossover trial of a branched-chain amino acid supplement.Randomized controlled trialHumanActiveThe American journal of clinical nutrition1992
Chin SE, Shepherd RW, Thomas BJ, et al.
Nucleotide sequences and characterization of liv genes encoding components of the high-affinity branched-chain amino acid transport system in Salmonella typhimurium.Other primary literatureUnknownActiveJournal of biochemistry1992
Matsubara K, Ohnishi K, Kiritani K
Effect of branched-chain amino acid supplementation on the exercise-induced change in aromatic amino acid concentration in human muscle.Other primary literatureHumanActiveActa physiologica Scandinavica1992
Blomstrand E, Newsholme EA
Lrp, a leucine-responsive protein, regulates branched-chain amino acid transport genes in Escherichia coli.Other primary literatureUnknownActiveJournal of bacteriology1992
Haney SA, Platko JV, Oxender DL, et al.
Branched-chain amino acid biosynthesis genes in Lactococcus lactis subsp. lactis.Other primary literatureUnknownActiveJournal of bacteriology1992
Godon JJ, Chopin MC, Ehrlich SD
Premature termination of in vivo transcription of a gene encoding a branched-chain amino acid transport protein in Escherichia coli.Other primary literatureUnknownActiveJournal of bacteriology1992
Williamson RM, Oxender DL
Branched-chain amino acid metabolism in isolated perfused liver of cirrhotic rats.Other primary literatureAnimalActiveScandinavian journal of gastroenterology1992
Blonde-Cynober F, De Bandt JP, Ballet F, et al.
Application of various concentrations of branched chain amino acid solutions for sub-total gastrectomyDesign not determinedUnknownUnknown[Ying yang xue bao] Acta nutrimenta Sinica1992
Zhang Xinkui, Lu Jiaqi, Li Junyou, et al.
Oral BCAA supplementation in cirrhosis with chronic encephalopathy: effects on prolactin and estradiol levels.Randomized controlled trialHumanActiveHepato-gastroenterology1992
Bianchi GP, Marchesini G, Zoli M, et al.
Influence of beta blockade on branched chain amino acid concentrations in cirrhosis.Other primary literatureHumanActiveHepato-gastroenterology1992
Eriksson LS, Söderman C
The BCAA/AAA ratio of plasma amino acids in three different groups of cirrhotics.Other primary literatureHumanActiveRevista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion1992
Campollo O, Sprengers D, McIntyre N
Insulin action on glucose and branched-chain amino acid metabolism in cancer cachexia: differential effects of insulin.Other primary literatureHumanActiveSurgery1992
Pisters PW, Cersosimo E, Rogatko A, et al.
Regulation of branched chain amino acid metabolism in ruminants.ReviewAnimalActiveDiabete & metabolisme1992
Papet I, Grizard J, Bonin D, et al.
[Metabolic effects of GFX+BCAA solution in the old aged rats after operation].Other primary literatureAnimalActiveNihon Geka Gakkai zasshi1992
Usami M, Ohyanagi H, Kasahara H, et al.
The effects of branched-chain amino acid-enriched elemental diet in patients with biliary atresia.Other primary literatureUnknownActiveAsia Pacific journal of clinical nutrition1992
Kawahara H, Fukui Y, Imura K, et al.
Prospective randomized double-blind trial of branched chain amino acid enriched versus standard parenteral nutrition solutions in traumatized and septic patients.Randomized controlled trialHumanActiveWorld journal of surgery1991
Vente JP, Soeters PB, von Meyenfeldt MF, et al.
Effect of glucose and branched chain amino acid (BCAA) infusion on onset of liver regeneration and plasma amino acid pattern in partially hepatectomized rats.Other primary literatureAnimalActiveJournal of hepatology1991
Holecek M, Simek J, Palicka V, et al.
Oral BCAA in the treatment of chronic hepatic encephalopathy.Other primary literatureHumanActiveJournal of hepatology1991
Marchesini G, Bianchi G, Zoli M
Branched-chain amino acid in chronic renal failure patients: respiratory and sleep effects.Randomized controlled trialHumanActiveKidney international1991
Söreide E, Skeie B, Kirvelä O, et al.
Branched-chain amino acid-free parenteral nutrition in the treatment of acute metabolic decompensation in patients with maple syrup urine disease.Other primary literatureHumanActiveThe New England journal of medicine1991
Berry GT, Heidenreich R, Kaplan P, et al.
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: valine metabolism at different leucine intakes.Randomized controlled trialHumanActiveThe American journal of clinical nutrition1991
Pelletier V, Marks L, Wagner DA, et al.
Branched-chain amino acid interactions with reference to amino acid requirements in adult men: leucine metabolism at different valine and isoleucine intakes.Randomized controlled trialHumanActiveThe American journal of clinical nutrition1991
Pelletier V, Marks L, Wagner DA, et al.
Acute C-peptide, insulin and branched chain amino acid response to feeding in formula and breast fed infants.Other primary literatureHumanActiveActa paediatrica Scandinavica1991
Wallensteen M, Lindblad BS, Zetterström R, et al.
Effect of branched-chain amino acid supplementation on mental performance.Other primary literatureHumanActiveActa physiologica Scandinavica1991
Blomstrand E, Hassmén P, Newsholme EA
Branched-Chain Amino Acid Transport in Cytoplasmic Membranes of Leuconostoc mesenteroides subsp. dextranicum CNRZ 1273.Other primary literatureUnknownActiveApplied and environmental microbiology1991
Winters DA, Poolman B, Hemme D, et al.
The absence of branched-chain amino acid and growth rate control at the internal ilvEp promoter of the ilvGMEDA operon.Other primary literatureUnknownActiveJournal of bacteriology1991
Harms EH, Umbarger HE
Isolation of the braZ gene encoding the carrier for a novel branched-chain amino acid transport system in Pseudomonas aeruginosa PAO.Other primary literatureUnknownActiveJournal of bacteriology1991
Hoshino T, Kose-Terai K, Uratani Y
Characterization of enzymes of the branched-chain amino acid biosynthetic pathway in Methanococcus spp.Other primary literatureUnknownActiveJournal of bacteriology1991
Xing RY, Whitman WB
Effect of alpha-ketoacid dehydrogenase phosphorylation on branched-chain amino acid metabolism in muscle.Other primary literatureAnimalActiveThe American journal of physiology1991
Hood DA, Terjung RL
Myocardial protein turnover in patients with coronary artery disease. Effect of branched chain amino acid infusion.Other primary literatureHumanActiveThe Journal of clinical investigation1991
Young LH, McNulty PH, Morgan C, et al.
[The effect of enriched branched chain amino acid solution with hypocaloric TPN on acute phase protein, plasma amino acid profile metabolism in postoperative children].Randomized controlled trialHumanActiveZhonghua wai ke za zhi [Chinese journal of surgery]1991
Xia HM
[The behavior of visceral proteins in digestive surgery patients undergoing total peripheral parenteral nutrition enriched with branched-chain amino acids (BCAA)].Other primary literatureHumanActiveRevista espanola de enfermedades digestivas1991
Ruiz Coracho P, Bellón Caneiro JM, García Parreño J, et al.
[Effect of branched chain amino acid (BCAA) enriched solution in postoperative patients receiving TPN].Other primary literatureHumanActiveNihon Geka Gakkai zasshi1991
Takeda Y
[Adverse effects of branched chain amino acid transfusion on type-II citrullinemia--report of an adult case].ReviewHumanActiveRinsho shinkeigaku = Clinical neurology1991
Shindo K, Tsunoda S, Shiozawa Z
[Effects of branched-chain amino acids (BCAA) in complete hypocaloric nutrition of surgical patients with neoplasms of the digestive tract].Other primary literatureHumanActiveNutricion hospitalaria1991
Ruiz Coracho P, Bellón Caneiro JM, García Parreño J, et al.
Effect of branched chain amino acid enrichment of total parenteral nutrition on nitrogen sparing and clinical outcome of sepsis and trauma: a prospective randomized double blind trial.Randomized controlled trialHumanActiveThe British journal of surgery1990
von Meyenfeldt MF, Soeters PB, Vente JP, et al.
Regulation of branched-chain amino acid biosynthesis in Neurospora crassa: cloning and characterization of the leu-1 and ilv-3 genes.Other primary literatureUnknownActiveMolecular & general genetics : MGG1990
Jarai G, Yagmai B, Fu YH, et al.
Cloning and nucleotide sequence of the gene braB coding for the sodium-coupled branched-chain amino acid carrier in Pseudomonas aeruginosa PAO.Other primary literatureUnknownActiveMolecular & general genetics : MGG1990
Hoshino T, Kose K, Uratani Y
Evaluation of branched-chain amino acid intake in children with maple syrup urine disease and methylmalonic aciduria.Other primary literatureHumanActiveJournal of inherited metabolic disease1990
Parsons HG, Carter RJ, Unrath M, et al.
Norleucine: a branched-chain amino acid analog affecting feeding behavior of rats.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior1990
Tews JK, Repa JJ, Harper AE
Long-term oral branched-chain amino acid treatment in chronic hepatic encephalopathy. A randomized double-blind casein-controlled trial. The Italian Multicenter Study Group.Randomized controlled trialHumanActiveJournal of hepatology1990
Marchesini G, Dioguardi FS, Bianchi GP, et al.
Failure of BCAA supplementation to promote nitrogen retention in injured patients.ReviewHumanActiveJournal of the American College of Nutrition1990
Scholten DJ, Morgan RE, Davis AT, et al.
Cloning and nucleotide sequences of livB and livC, the structural genes encoding binding proteins of the high-affinity branched-chain amino acid transport in Salmonella typhimurium.Other primary literatureUnknownActiveJournal of biochemistry1990
Ohnishi K, Nakazima A, Matsubara K, et al.
Branched Chain Amino Acid Metabolism in the Biosynthesis of Lycopersicon pennellii Glucose Esters.Other primary literatureUnknownActivePlant physiology1990
Walters DS, Steffens JC
Modified branched-chain amino acid pathways give rise to acyl acids of sucrose esters exuded from tobacco leaf trichomes.Other primary literatureUnknownActiveEuropean journal of biochemistry1990
Kandra G, Severson R, Wagner GJ
Influence of branched chain amino acid infusions on wound healing.Other primary literatureAnimalActiveThe Australian and New Zealand journal of surgery1990
McCauley R, Platell C, Hall J, et al.
Cloning, nucleotide sequences, and identification of products of the Pseudomonas aeruginosa PAO bra genes, which encode the high-affinity branched-chain amino acid transport system.Other primary literatureUnknownActiveJournal of bacteriology1990
Hoshino T, Kose K
Genetic analysis of the Pseudomonas aeruginosa PAO high-affinity branched-chain amino acid transport system by use of plasmids carrying the bra genes.Other primary literatureUnknownActiveJournal of bacteriology1990
Hoshino T, Kose K
Branched chain amino acid regulation of the ILV2 locus in Saccharomyces cerevisiae.Other primary literatureUnknownActiveGenome1990
Xiao W, Rank GH
Glucocorticoid regulation of muscle branched-chain amino acid metabolism.Other primary literatureAnimalActiveMedicine and science in sports and exercise1990
Block KP, Buse MG
Effects of partial hepatectomy on the enzymes of cerebral glutamate and branched-chain amino acid metabolism.Other primary literatureAnimalActiveBiochemistry international1990
Jessy J, Rao VL, Murthy CR
Liver regeneration after partial hepatectomy: effects of glucose and branched-chain amino acid.Other primary literatureAnimalActiveJournal of the Formosan Medical Association = Taiwan yi zhi1990
Lai HS, Chen WJ, Chen KM
[An experimental and clinical study of energy-protein metabolism and host defense-repair mechanism in postoperative period--a significance of administration of branched chain amino acid].Randomized controlled trialHuman & animalActiveNihon Geka Gakkai zasshi1990
Shimazu Y
Branched-chain amino acid-supplemented nutritional support after gastrectomy for gastric cancer with special reference to plasma amino acid profiles.Other primary literatureHumanActiveNutrition (Burbank, Los Angeles County, Calif.)1990
Yamanaka H, Kanemaki T, Tsuji M, et al.
Branched-chain amino acid enriched diet given simultaneously with ethanol partially prevents morphological and biochemical changes in the liver.Other primary literatureAnimalActivePatologia polska1990
Farbiszewski R, Chyczewski L, Hołownia A, et al.
Effects of chronic oral branched-chain amino acid supplementation in a subpopulation of cirrhotics.Other primary literatureHumanActiveClinical physiology and biochemistry1990
Dioguardi FS, Brigatti M, Dell'Oca M, et al.
Na+(Li+)/branched-chain amino acid cotransport in Pseudomonas aeruginosa.Other primary literatureUnknownActiveThe Journal of membrane biology1989
Uratani Y, Tsuchiya T, Akamatsu Y, et al.
Intra- and extracellular amino acid concentrations in portacaval-shunted rabbits. Role of hyperammonemia and effects of branched-chain amino acid-enriched parenteral nutrition.Other primary literatureAnimalActiveZeitschrift fur Ernahrungswissenschaft1989
Leweling H, Staedt U, Striebel JP, et al.
Influence of branched-chain amino acid composition of culture media on the synthesis of plasma proteins by serum-free cultured rat hepatocytes.Other primary literatureAnimalActiveIn vitro cellular & developmental biology : journal of the Tissue Culture Association1989
Montoya A, Gómez-Lechón MJ, Castell JV
Effect of long-term oral supplementation with branched-chain amino acid granules on the prognosis of liver cirrhosis.Other primary literatureHumanActiveGastroenterologia Japonica1989
Yoshida T, Muto Y, Moriwaki H, et al.
The regulation of fatty acid and branched-chain amino acid oxidation in cancer cachectic rats: a proposed role for a cytokine, eicosanoid, and hormone trilogy.Other primary literatureAnimalActiveBiochemical medicine and metabolic biology1989
Siddiqui RA, Williams JF
Difference in sodium requirement of branched chain amino acid carrier between Pseudomonas aeruginosa PAO and PML strains is due to substitution of an amino acid at position 292.Other primary literatureUnknownActiveThe Journal of biological chemistry1989
Uratani Y, Hoshino T
The effect of amino acids on the ischemic heart. Improvement of oxygenated crystalloid cardioplegic solution by an enriched branched chain amino acid formulation.Other primary literatureAnimalActiveThe Journal of thoracic and cardiovascular surgery1989
Schwalb H, Izhar U, Yaroslavsky E, et al.
Branched chain amino acid perfusion.Other primary literatureHuman & animalActiveThe Journal of thoracic and cardiovascular surgery1989
McMillin JB
Amino acid sequence of Salmonella typhimurium branched-chain amino acid aminotransferase.Other primary literatureUnknownActiveBiochemistry1989
Feild MJ, Nguyen DC, Armstrong FB
Activities of branched-chain amino acid--degrading enzymes in liver from rats fed different dietary levels of protein.Other primary literatureAnimalActiveThe Journal of nutrition1989
Soemitro S, Block KP, Crowell PL, et al.
Crystallization and preliminary X-ray characterization of branched-chain amino acid aminotransferase from Escherichia coli.Other primary literatureUnknownActiveJournal of biochemistry1989
Kamitori S, Odagaki Y, Inoue K, et al.
Sodium-dependent transport of branched-chain amino acids by a monensin-sensitive ruminal peptostreptococcus.Other primary literatureAnimalActiveApplied and environmental microbiology1989
Chen GJ, Russell JB
Branched-chain amino acid support of stressed patients.ReviewHumanActiveDICP : the annals of pharmacotherapy1989
Oki JC, Cuddy PG
[A clinical study of amino acid metabolism in cancerous hypoproteinemia--the role of branched chain amino acids (BCAA) and appropriate compositions of BCAA in parenteral nutrition].Other primary literatureHumanActiveGan no rinsho. Japan journal of cancer clinics1989
Fukui S, Aoki H, Mizushima Y, et al.
[A study of adequate energy, amino acid, and carbohydrate requirements in postoperative total parenteral nutrition--the effect of branched chain amino acid (BCAA) and carbohydrate mixture of glucose, fructose, and xylitol (GFX)].Other primary literatureHumanActiveNihon Geka Gakkai zasshi1989
Hayashida K, Mashima Y, Tashiro T, et al.
[The effect of enriched branched chain amino acid solution on amino acid metabolism during perioperative total parenteral nutrition support].Randomized controlled trialHumanActiveZhonghua wai ke za zhi [Chinese journal of surgery]1989
He GZ
[Studies of solutions with various branched-chain amino acid contents on protein metabolism in the postoperative period. 1. A 15N tracer kinetic animal model for evaluating the effect of parenteral amino acid administration on nitrogen metabolism].Other primary literatureAnimalActiveInfusionstherapie (Basel, Switzerland)1989
Matkowitz R, Hartig W, Ritter R, et al.
BCAA-enriched solution and hepatic encephalopathy.Other primary literatureHumanActiveSurgery1989
Okada A
Role of mitochondrial transamination in branched chain amino acid metabolism.Other primary literatureAnimalActiveThe Journal of biological chemistry1988
Hutson SM, Fenstermacher D, Mahar C
Radiochemical high-performance liquid chromatography methods for the study of branched-chain amino acid metabolism.Other primary literatureUnknownActiveMethods in enzymology1988
Bartlett K, Causey AG
Use of rat hindquarter preparations in studies o branched-chain amino acid metabolism.Other primary literatureAnimalActiveMethods in enzymology1988
Davis EJ, Lee SH, Spydevold O, et al.
Rapid changes in urinary serine and branched-chain amino acid excretion among diabetic patients during insulin treatment.Other primary literatureHumanActiveDiabetes research and clinical practice1988
Sasaki M, Sato K, Maruhama Y
Lipid requirement of the branched-chain amino acid transport system of Streptococcus cremoris.Other primary literatureUnknownActiveBiochemistry1988
Driessen AJ, Zheng T, In't Veld G, et al.
Subcellular localization of branched-chain amino acid aminotransferase and lactate dehydrogenase C4 in rat and mouse spermatozoa.Other primary literatureAnimalActiveThe Biochemical journal1988
Montamat EE, Vermouth NT, Blanco A
Influence of dietary leucine content on the activities of branched-chain amino acid aminotransferase (EC 2.6.1.42) and branched-chain alpha-keto acid dehydrogenase (EC 1.2.4.4) complex in tissues of preruminant lambs.Other primary literatureAnimalActiveThe British journal of nutrition1988
Papet I, Lezebot N, Barre F, et al.
Intravenously infused carnitine: influence on protein and branched-chain amino acid metabolism in starved and parenterally fed rats.Other primary literatureAnimalActiveThe American journal of clinical nutrition1988
Vazquez JA, Paul HS, Adibi SA
Branched-chain amino acid aminotransferase of Escherichia coli: overproduction and properties.Other primary literatureUnknownActiveJournal of biochemistry1988
Inoue K, Kuramitsu S, Aki K, et al.
A kinetic study of leucine metabolism in severely burned patients. Comparison between a conventional and branched-chain amino acid-enriched nutritional therapy.Other primary literatureHumanActiveAnnals of surgery1988
Yu YM, Wagner DA, Walesreswski JC, et al.
Administration of balanced or BCAA-enriched amino acid solution in septic rats. Effects on protein synthesis in the liver.Other primary literatureAnimalActiveAnnals of surgery1988
Pedersen P, Li SJ, Hasselgren PO, et al.
Pharmacological reversal of abnormal glucose regulation, BCAA utilization, and muscle catabolism in sepsis by dichloroacetate.Other primary literatureAnimalActiveThe Journal of trauma1988
Vary TC, Siegel JH, Zechnich A, et al.
Inhibition of post-traumatic septic proteolysis and ureagenesis and stimulation of hepatic acute-phase protein production by branched-chain amino acid TPN.Randomized controlled trialHumanActiveThe Journal of trauma1988
Chiarla C, Siegel JH, Kidd S, et al.
Skeletal muscle and whole body protein turnover in cardiac cachexia: influence of branched-chain amino acid administration.Other primary literatureHumanActiveEuropean journal of clinical investigation1988
Morrison WL, Gibson JN, Rennie MJ
Effect of cholesterol on the branched-chain amino acid transport system of Streptococcus cremoris.Other primary literatureUnknownActiveJournal of bacteriology1988
Zheng T, Driessen AJ, Konings WN
Common ancestry of Escherichia coli pyruvate oxidase and the acetohydroxy acid synthases of the branched-chain amino acid biosynthetic pathway.Other primary literatureUnknownActiveJournal of bacteriology1988
Chang YY, Cronan JE Jr
LEU3 of Saccharomyces cerevisiae activates multiple genes for branched-chain amino acid biosynthesis by binding to a common decanucleotide core sequence.Other primary literatureUnknownActiveMolecular and cellular biology1988
Friden P, Schimmel P
Regulation of leucine catabolism by caloric sources. Role of glucose and lipid in nitrogen sparing during nitrogen deprivation.Other primary literatureAnimalActiveThe Journal of clinical investigation1988
Vazquez JA, Paul HS, Adibi SA
Infusion of a branched-chain amino acid-enriched solution and alpha-ketoisocaproic acid in septic rats: effects on nitrogen balance and skeletal muscle protein turnover.Other primary literatureAnimalActiveJPEN. Journal of parenteral and enteral nutrition1988
Hasselgren PO, LaFrance R, Pedersen P, et al.
Effect of branched-chain amino acid on 15N incorporation into liver and skeletal muscle proteins following [15N]-ammonium chloride administration to carbon tetrachloride-intoxicated rats.Other primary literatureAnimalActiveJournal of nutritional science and vitaminology1988
Okita M, Watanabe A, Tsuji T
Lack of preventive effect of branched-chain amino acid solution on postoperative hepatic encephalopathy in patients with cirrhosis: a randomized, prospective trial.Randomized controlled trialHumanActiveSurgery1988
Kanematsu T, Koyanagi N, Matsumata T, et al.
Effects of branched chain amino acid-enriched total parenteral nutrition on amino acid utilization in rats bearing Yoshida sarcoma.Other primary literatureAnimalActiveCancer research1988
Crosby LE, Bistrian BR, Ling PR, et al.
[The role of specialized parenteral nutrition in the comprehensive care of Reye's syndrome. Use of branched-chain amino acid solutions in a comparative study of 2 groups (28 and 23) of treated children].Other primary literatureHumanActiveCeskoslovenska pediatrie1988
Pachl J, Kruf M, Bulant V, et al.
Branched chain amino acid transaminases in brain in methionine sulphoximine (MSI) toxicity.Other primary literatureAnimalActiveBiochemistry international1988
Jessy J, Murthy CR
Branched-chain amino acid administration in surgical patients. Effects on amino acid and fuel substrate profiles.Other primary literatureHumanActiveArchives of surgery (Chicago, Ill. : 1960)1987
Desai SP, Bistrian BR, Palombo JD, et al.
Comparison between acute and chronic effects of ammonia on branched-chain amino acid oxidation and incorporation into protein in primary cultures of astrocytes and of neurons.Other primary literatureAnimalActiveJournal of neuroscience research1987
Murthy CR, Hertz L
Failure of a branched chain amino acid-enriched diet to reverse ethanol inhibition of cardiac protein synthesis in the rat.Other primary literatureAnimalActiveThe International journal of biochemistry1987
Verschuer L, Ward LC
The protective effect of enriched branched chain amino acid formulation in the ischemic heart: a phosphorous-31 nuclear magnetic resonance study.Other primary literatureAnimalActiveJournal of molecular and cellular cardiology1987
Schwalb H, Kushnir T, Navon G, et al.
Acidosis, not azotemia, stimulates branched-chain, amino acid catabolism in uremic rats.Other primary literatureAnimalActiveKidney international1987
Hara Y, May RC, Kelly RA, et al.
Activities of branched-chain amino acid aminotransferase and branched-chain 2-oxo acid dehydrogenase complex in tissues of maternal and fetal sheep.Other primary literatureAnimalActiveThe Biochemical journal1987
Goodwin GW, Gibboney W, Paxton R, et al.
Acute effect of ammonia on branched-chain amino acid oxidation and incorporation into proteins in astrocytes and in neurons in primary cultures.Other primary literatureAnimalActiveJournal of neurochemistry1987
Murthy CR, Hertz L
Toxic accumulation of alpha-ketobutyrate caused by inhibition of the branched-chain amino acid biosynthetic enzyme acetolactate synthase in Salmonella typhimurium.Other primary literatureUnknownActiveJournal of bacteriology1987
LaRossa RA, Van Dyk TK, Smulski DR
Branched-chain amino acid metabolism in rat muscle: abnormal regulation in acidosis.Other primary literatureAnimalActiveThe American journal of physiology1987
May RC, Hara Y, Kelly RA, et al.
Effect of maternal fasting on ovine fetal and maternal branched-chain amino acid transaminase activities.Other primary literatureAnimalActiveBiology of the neonate1987
Liechty EA, Barone S, Nutt M
Intravenous branched chain amino acid trial in marrow transplant recipients.Randomized controlled trialHumanActiveJPEN. Journal of parenteral and enteral nutrition1987
Lenssen P, Cheney CL, Aker SN, et al.
Enteral and parenteral branched chain amino acid-supplemented nutritional support in patients with encephalopathy due to alcoholic liver disease.Randomized controlled trialHumanActiveJPEN. Journal of parenteral and enteral nutrition1987
O'Keefe SJ, Ogden J, Dicker J
Branched-chain amino acid carbon and nitrogen arteriovenous concentration differences across the ovine fetal hindlimb.Other primary literatureAnimalActivePediatric research1987
Liechty EA, Polak MJ, Lemons JA
Exercise-induced changes in branched chain amino acid/aromatic amino acid ratio in the rat brain and plasma.Other primary literatureAnimalActiveJapanese journal of pharmacology1987
Okamura K, Matsubara F, Yoshioka Y, et al.
Muscle amino acid flux in patients receiving branched-chain amino acid solutions after surgery.Other primary literatureHumanActiveSurgery1987
Bonau RA, Jeevanandam M, Moldawer L, et al.
[Treatment of hepatic encephalopathy with branched-chain amino acids (BCAA) by oral route: II. Chronic hepatic encephalopathy].Other primary literatureHumanActiveRevista espanola de las enfermedades del aparato digestivo1987
Caballería Rovira E, Arago López JV, Masso Ubeda RM, et al.
Improved protein kinetics and albumin synthesis by branched chain amino acid-enriched total parenteral nutrition in cancer cachexia. A prospective randomized crossover trial.Randomized controlled trialHumanActiveCancer1986
Tayek JA, Bistrian BR, Hehir DJ, et al.
Cloning, expression, and nucleotide sequence of livR, the repressor for high-affinity branched-chain amino acid transport in Escherichia coli.Other primary literatureUnknownActiveProteins1986
Antonucci TK, Wagner LM, Oxender DL
Dihydrolipoyl dehydrogenase deficiency: a therapeutic trial with branched-chain amino acid restriction.Other primary literatureHumanActiveEuropean journal of pediatrics1986
Sakaguchi Y, Yoshino M, Aramaki S, et al.
Insulin stimulates branched chain amino acid uptake and diminishes nitrogen flux from skeletal muscle of injured patients.Other primary literatureHumanActiveThe Journal of surgical research1986
Brooks DC, Bessey PQ, Black PR, et al.
Branched chain amino acid enriched parenteral nutrition in surgical intensive care patients.Other primary literatureUnknownActiveClinical nutrition (Edinburgh, Scotland)1986
Takala J, Klossner J
Prevention of ammonia-induced brain edema in dogs infused with a branched-chain amino acid solution.Other primary literatureAnimalActiveBiochemical medicine and metabolic biology1986
Fujiwara M, Watanabe A, Hashimoto M, et al.
Regulation of branched-chain amino acid metabolism.Other primary literatureAnimalActiveBiochemical Society transactions1986
Harris RA, Paxton R, Goodwin GW, et al.
Branched chain amino acid-enriched solutions in the septic patient. A randomized, prospective trial.Randomized controlled trialHumanActiveAnnals of surgery1986
Bower RH, Muggia-Sullam M, Vallgren S, et al.
Branched chain amino acid uptake and muscle free amino acid concentrations predict postoperative muscle nitrogen balance.Other primary literatureAnimalActiveAnnals of surgery1986
Johnson DJ, Jiang ZM, Colpoys M, et al.
Effect of branched chain amino acid infusions on body protein metabolism in cirrhosis of liver.Randomized controlled trialHumanActiveGut1986
Wright PD, Holdsworth JD, Dionigi P, et al.
Branched-chain amino acid interactions in skeletal muscle: isoleucine and L-alloisoleucine.Other primary literatureAnimalActiveJPEN. Journal of parenteral and enteral nutrition1986
Downey RS, Karl IE, Bier DM
Branched chain amino acid enriched solutions in the septic patient.Other primary literatureHumanActiveAnnals of surgery1986
Piccolboni D
Whole-body nitrogen and tyrosine metabolism in surgical patients receiving branched-chain amino acid solutions.Randomized controlled trialHumanActiveArchives of surgery (Chicago, Ill. : 1960)1985
Desai SP, Bistrian BR, Moldawer LL, et al.
Use of an intravenous branched chain amino acid enriched diet in the tumor-bearing rat.Other primary literatureAnimalActiveThe Japanese journal of surgery1985
Kawamura I, Sato H, Ogoshi S, et al.
Effects of total parenteral nutrition enriched with branched chain amino acid infusion on liver function and serum amino acid pattern in dogs undergoing hepatectomy.Other primary literatureAnimalActiveLa Ricerca in clinica e in laboratorio1985
De Caterina M, Piccolboni D, Alfieri R, et al.
A method for branched-chain amino acid aminotransferase activity in microgram and nanogram tissue samples.Other primary literatureAnimalActiveAnalytical biochemistry1985
Hintz CS, Turk WR, Cambon N, et al.
Effect of clofibrate on branched-chain amino acid metabolism.Other primary literatureAnimalActiveBiochemical pharmacology1985
Wagenmakers AJ, Veerkamp JH, Schepens JT, et al.
Differential effect of dichloroacetate on branched-chain amino acid catabolism in perfused rat hindlimbs.Other primary literatureAnimalActiveFEBS letters1985
Schadewaldt P, Radeck W, Staib W
Use of a branched chain amino acid enriched solution in patients under metabolic stress.Other primary literatureHumanActiveAmerican journal of surgery1985
Bower RH, Kern KA, Fischer JE
The complete nucleotide sequences of the Escherichia coli LIV-BP and LS-BP genes. Implications for the mechanism of high-affinity branched-chain amino acid transport.Other primary literatureUnknownActiveThe Journal of biological chemistry1985
Landick R, Oxender DL
Affinity chromatography of B6-vitamin-dependent enzymes: purification of pig-heart branched-chain amino acid transaminase.Other primary literatureAnimalActiveJournal of chromatography1985
Korpela TK, Saarinen R
Controlled trial of nutritional supplementation, with and without branched chain amino acid enrichment, in treatment of acute alcoholic hepatitis.Randomized controlled trialHumanActiveJournal of hepatology1985
Calvey H, Davis M, Williams R
Branched-chain amino acid aminotransferase along the rabbit and rat nephron.Other primary literatureAnimalActiveKidney international1985
Burch HB, Cambon N, Lowry OH
Branched-chain amino acid metabolism and alanine formation in rat muscles in vitro. Mitochondrial-cytosolic interrelationships.Other primary literatureAnimalActiveThe Biochemical journal1985
Snell K, Duff DA
Branched chain amino acid therapy in liver disease.ReviewHumanActiveJournal of the American College of Nutrition1985
Maddrey WC
Microbial growth in branched-chain amino acid nutrient solutions.Other primary literatureUnknownActiveAmerican journal of hospital pharmacy1985
Blue VS, Mayhall CG, Pesko LJ, et al.
Branched-chain amino acid aminotransferase of Escherichia coli: nucleotide sequence of the ilvE gene and the deduced amino acid sequence.Other primary literatureUnknownActiveJournal of biochemistry1985
Kuramitsu S, Ogawa T, Ogawa H, et al.
Identification of livG, a membrane-associated component of the branched-chain amino acid transport in Escherichia coli.Other primary literatureUnknownActiveJournal of bacteriology1985
Nazos PM, Mayo MM, Su TZ, et al.
Regional and subcellular distribution of enzymes of branched-chain amino acid metabolism in brains of normal and diabetic rats.Other primary literatureAnimalActiveCanadian journal of physiology and pharmacology1985
Brosnan ME, Lowry A, Wasi Y, et al.
Effect of dietary fat, carbohydrate, and protein on branched-chain amino acid catabolism during caloric restriction.Other primary literatureHumanActiveThe Journal of clinical investigation1985
Vazquez JA, Morse EL, Adibi SA
Standard or branched-chain amino acid infusions as short-term nutritional support in liver cirrhosis?Randomized controlled trialHumanActiveJPEN. Journal of parenteral and enteral nutrition1985
Rocchi E, Cassanelli M, Gibertini P, et al.
Enriched branched-chain amino acid formula versus a casein-based supplement in the treatment of cirrhosis.Randomized controlled trialHumanActiveJPEN. Journal of parenteral and enteral nutrition1985
Christie ML, Sack DM, Pomposelli J, et al.
Branched chain amino acid transaminase and branched chain alpha-ketoacid dehydrogenase activity in the brain, liver and skeletal muscle of acute hepatic failure rats.Other primary literatureAnimalActiveActa medica Okayama1985
Takei N
Plasma branched chain amino acid abnormalities in sake-treated rats.Other primary literatureHuman & animalActiveActa medica Okayama1985
Watanabe A, Nakatsukasa H, Kobayashi M, et al.
Nutritional treatment of liver cirrhosis by branched-chain amino acid-enriched nutrient mixture.Other primary literatureHumanActiveJournal of nutritional science and vitaminology1985
Okita M, Watanabe A, Nagashima H
Effect of branched chain amino acid-enriched amino acid solution on normalization of plasma amino acids in hepatic encephalopathy.Other primary literatureHumanActiveTaiwan yi xue hui za zhi. Journal of the Formosan Medical Association1985
Liaw KY, Chang CN, Wei TC, et al.
In vivo measurement of leucine metabolism with stable isotopes in normal subjects and in those with cirrhosis fed conventional and branched-chain amino acid-enriched diets.Other primary literatureHumanActiveSurgery1985
Millikan WJ Jr, Henderson JM, Galloway JR, et al.
Modulation of branched-chain amino acid oxidation in rat hemidiaphragms in vitro by glucose and ketone bodies.Other primary literatureAnimalActiveBiochemistry international1985
Palmer TN, Caldecourt MA, Warner JP, et al.
Localization of a gene which complements branched-chain amino acid transaminase deficiency to the short arm of human chromosome 12.Other primary literatureHuman & animalActiveHuman genetics1984
Jones C, Moore EE
Characteristics of pancreatic branched chain amino acid aminotransferases from rat, man and dog.Other primary literatureHuman & animalActiveComparative biochemistry and physiology. B, Comparative biochemistry1984
Makino M, Minatogawa Y, Okuno E, et al.
Hydroxycarboxylic and oxocarboxylic acids in urine: products from branched-chain amino acid degradation and from ketogenesis.Other primary literatureHumanActiveJournal of chromatography1984
Liebich HM, Först C
Body protein metabolism and plasma amino acids in cirrhosis of the liver. The effect of varying the branched chain amino acid content of intravenous amino acid solutions.Other primary literatureUnknownActiveClinical nutrition (Edinburgh, Scotland)1984
Holdsworth JD, Dionigi P, Clague MB, et al.
The effect of starvation on branched-chain 2-oxo acid oxidation in rat muscle.Other primary literatureAnimalActiveThe Biochemical journal1984
Wagenmakers AJ, Veerkamp JH
Branched-chain amino acid metabolism and alanine formation in rat diaphragm muscle in vitro. Effects of dichloroacetate.Other primary literatureAnimalActiveThe Biochemical journal1984
Snell K, Duff DA
Branched-chain amino acid metabolism.ReviewHuman & animalActiveAnnual review of nutrition1984
Harper AE, Miller RH, Block KP
High-branched chain amino acid solutions: relationship of composition to efficacy.Randomized controlled trialHumanActiveJPEN. Journal of parenteral and enteral nutrition1984
Bonau RA, Jeevanandam M, Daly JM
Prevention of methionine and ammonia-induced coma by intravenous infusion of a branched chain amino acid solution to rats with liver injury.Other primary literatureAnimalActiveActa medica Okayama1984
Shiota T, Watanabe A, Higashi T, et al.
Influence of basic and branched chain amino acid interactions on the lysine and valine requirements of young turkeys.Other primary literatureAnimalActivePoultry science1984
Jackson S, Potter LM
Branched-chain ketoacid dehydrogenase activity and growth of normal and mutant human fibroblasts: the effect of branched-chain amino acid concentration in culture medium.Other primary literatureHumanActiveBiochemical genetics1983
Danner DJ, Priest JH
Effects of branched chain amino acid infusion on glucose metabolism in cirrhotic patients with encephalopathy.Other primary literatureHumanActiveGastroenterologia Japonica1983
Morioka S, Kanai K, Kako M, et al.
Branched-chain amino acid aminotransferase in submandibular gland of the rat.Other primary literatureAnimalActiveArchives of oral biology1983
Kawagishi S, Shinozaki F
Characterization of enzymatic deficiencies of branched chain amino-acid catabolism in human fibroblasts by genetic complementation.Other primary literatureHumanActiveBiochemical and biophysical research communications1983
Coudé FX, Grimber G, Parvy P, et al.
Branched-chain amino acid aminotransferase activity in the tissues of lake trout.Other primary literatureAnimalActiveComparative biochemistry and physiology. B, Comparative biochemistry1983
Hughes SG, Rumsey GL, Nesheim MC
Alterations in tyrosine and protein kinetics produced by injury and branched chain amino acid administration in rats.Other primary literatureAnimalActiveClinical science (London, England : 1979)1983
Sakamoto A, Moldawer LL, Palombo JD, et al.
Nitrogen retention in critically ill patients is proportional to the branched chain amino acid load.Randomized controlled trialHumanActiveCritical care medicine1983
Cerra FB, Mazuski J, Teasley K, et al.
Genetic mapping of bra genes affecting branched-chain amino acid transport in Pseudomonas aeruginosa.Other primary literatureUnknownActiveJournal of bacteriology1983
Hoshino T, Tsuda M, Iino T, et al.
Effect of a branched chain amino acid-enriched nutritional product on the pathophysiology of the liver and nutritional state of patients with liver cirrhosis.Other primary literatureHumanActiveActa medica Okayama1983
Watanabe A, Shiota T, Okita M, et al.
Comparative study of amino acid, ammonia and pancreatic hormone levels in the blood of cirrhotic patients following intragastric and intravenous administration of a branched-chain amino acid-enriched solution.Other primary literatureHumanActiveActa medica Okayama1983
Watanabe A, Hayashi S, Shiota T, et al.
[Purification And Properties Of Branched Chain Amino Acid Aminotransferase From Fasciola Hepatica]Other primary literatureUnknownActiveKisaengch'unghak chapchi. The Korean journal of parasitology1983
Lee JH, Lee DW, Lee HS, et al.
Branched-chain amino acid-enriched elemental diet in patients with cirrhosis of the liver. A double blind crossover trial.Other primary literatureHumanActiveZeitschrift fur Gastroenterologie1983
Sieg A, Walker S, Czygan P, et al.
Branched-chain amino acid metabolism in chronic renal failure.Other primary literatureHumanActiveKidney international. Supplement1983
Tizianello A, Deferrari G, Garibotto G, et al.
[Selection of mutant branched-chain amino acid producers in the methylotrophic yeasts Hansenula polymorpha].Other primary literatureUnknownActiveMikrobiologiia1983
Titorenko VI, Trotsenko IuA
Anticatabolic effect of branched-chain amino acid-enriched solutions in patients with liver cirrhosis.Other primary literatureHumanActiveHepatology (Baltimore, Md.)1982
Marchesini G, Zoli M, Dondi C, et al.
Parenteral branched-chain amino acid treatment and avian dystrophy.Other primary literatureAnimalActiveMuscle & nerve1982
Hudecki MS, Pollina CM, Heffner RR
Effects of intraduodenal feeding of a branched-chain amino acid-rich solution on ammonia-induced encephalopathy in liver-injured rats.Other primary literatureAnimalActiveGastroenterologia Japonica1982
Hayashi S, Watanabe A, Shiota T, et al.
Cytosolic and mitochondrial isoenzymes of branched-chain amino acid aminotransferase during development of the rat.Other primary literatureAnimalActiveThe Biochemical journal1982
Kadowaki H, Knox WE
Involvement of food intake and amino acid catabolism in the branched-chain amino acid antagonism in chicks.Other primary literatureAnimalActiveThe Journal of nutrition1982
Calvert CC, Klasing KC, Austic RE
Plasma amino acid concentrations during branched-chain amino acid infusions in stressed patients.Other primary literatureHumanActiveThe Journal of trauma1982
Desai SP, Bistrian BR, Moldawer LL, et al.
[High branched-chain amino acid formulations in hepatic encephalopathy].Other primary literatureHumanActiveHarefuah1982
Muggia-Sulam M, Freund HR
[Abnormal amino acid metabolism in serious liver diseases: branched chain amino acid and aromatic amino acid metabolism].Other primary literatureHumanActiveNihon rinsho. Japanese journal of clinical medicine1982
Sato Y
[Awakening effects of branched-chain amino acid infusion in hepatic coma].Other primary literatureHumanActiveNihon rinsho. Japanese journal of clinical medicine1982
Kaito I, Suzuki K, Kato A, et al.
Treatment of liver cirrhosis with branched chain amino acid-supplemented diet.Other primary literatureHumanActiveGastroenterologia Japonica1981
Okita M, Watanabe A, Nagashima H
Branched-chain amino acid fermentation by a marine spirochete: strategy for starvation survival.Other primary literatureUnknownActiveJournal of bacteriology1981
Harwood CS, Canale-Parola E
Adenosine 5'-triphosphate- yielding pathways of branched-chain amino acid fermentation by a marine spirochete.Other primary literatureUnknownActiveJournal of bacteriology1981
Harwood CS, Canale-Parola E
Effect of glucose and/or branched chain amino acid infusion on plasma amino acid imbalance in chronic liver failure.Other primary literatureHumanActiveJPEN. Journal of parenteral and enteral nutrition1981
Rossi-Fanelli F, Angelico M, Cangiano C, et al.
[The metabolic effect of branched-chain amino acid (author's transl)].Other primary literatureHuman & animalActiveSheng li ke xue jin zhan [Progress in physiology]1981
Jiang LR
The in vitro synthesis and processing of the branched-chain amino acid binding proteins.Other primary literatureUnknownActiveJournal of supramolecular structure1980
Daniels CJ, Anderson JJ, Landick R, et al.
Excretion pattern of branched-chain amino acid metabolites during the course of acute infections in a patient with methylmalonic acidaemia.Other primary literatureHumanActiveJournal of inherited metabolic disease1980
Kølvraa S, Gregersen N, Christensen E, et al.
Enzymic determination of branched-chain amino acids and 2-oxoacids in rat tissues. Transfer of 2-oxoacids from skeletal muscle to liver in vivo.Other primary literatureAnimalActiveThe Biochemical journal1980
Livesey G, Lund P
Structural and functional analysis of cloned DNA containing genes responsible for branched-chain amino acid transport in Escherichia coli.Other primary literatureUnknownActiveProceedings of the National Academy of Sciences of the United States of America1980
Oxender DL, Anderson JJ, Daniels CJ, et al.
Evaluation of an infusion solution enriched with branched chain amino acid in parenteral nutrition of rats.Other primary literatureAnimalActiveThe Journal of nutrition1980
Kishi T, Iwasawa Y, Itoh H, et al.
Branched-chain amino acid transport in Streptococcus agalactiae.Other primary literatureUnknownActiveApplied and environmental microbiology1980
Moran JW
Branched chain amino acid oxidation in cultured rat skeletal muscle cells. Selective inhibition by clofibric acid.Other primary literatureAnimalActiveThe Journal of clinical investigation1980
Pardridge WM, Casanello-Ertl D, Duducgian-Vartavarian L
Branched-chain amino acid nitrogen transfer to alamine in vivo in dogs. Direct isotopic determination with [15N]leucine.Other primary literatureAnimalActiveThe Journal of clinical investigation1980
Galim EB, Hruska K, Bier DM, et al.
Branched chain amino acid aminotransferase isoenzymes of Pseudomonas cepacia.Other primary literatureHumanActiveArchives of microbiology1979
Wong HC, Lessie TG
Differential alterations in branched-chain amino acid decarboxylation in liver of hypophysectomized rats.Other primary literatureAnimalActiveExperientia1979
Sullivan SG, Potter DA, Krauss MR, et al.
The relA locus specifies a positive effector in branched-chain amino acid transport regulation.Other primary literatureUnknownActiveJournal of bacteriology1979
Quay SC, Oxender DL
alpha-Ketoisocaproate stimulates branched-chain amino acid transaminase in kidney and muscle.Other primary literatureAnimalActiveThe American journal of physiology1979
Mitch WE, Chan W
Inhibition of the glycine cleavage system by branched-chain amino acid metabolites.Other primary literatureAnimalActivePediatric research1979
Kølvraa S
Antioxidant properties of branched-chain amino acid derivatives.Other primary literatureUnknownActiveChemical & pharmaceutical bulletin1979
Kawashima K, Itoh H, Miyoshi M, et al.
Branched chain amino acid administration and metabolism during starvation, injury, and infection.Other primary literatureAnimalActiveSurgery1979
Blackburn GL, Moldawer LL, Usui S, et al.
Serum amino acids in hepatic encephalopathy--effects of branched chain amino acid infusion on serum aminogram.Other primary literatureHumanActiveActa hepato-gastroenterologica1979
Watanabe A, Takesue A, Higashi T, et al.
Branched chain amino acid metabolism in low birth weight babies and the effects of dietary protein quality.Other primary literatureHumanActiveThe Proceedings of the Nutrition Society1979
Scott PH, Berger HM, Wharton BA
In vivo evidence for the unique nitrogen-sparing mechanism of branched-chain amino acid administration.Other primary literatureAnimalActiveSurgical forum1979
Sakamoto A, Moldawer LL, Usui S, et al.
Branched chain amino acid metabolism in the retina of diabetic rats.Other primary literatureAnimalActiveDiabetologia1978
Frayser R, Buse MG
Leucine oxidation in diabetes and starvation: effects of ketone bodies on branched-chain amino acid oxidation in vitro.Other primary literatureAnimalActiveMetabolism: clinical and experimental1978
Paul HS, Adibi SA
Effect of branched-chain keto-acids and dietary protein content on the activity of branched-chain amino acid transferase in rat tissues.Other primary literatureAnimalActiveThe Journal of nutrition1978
Chan W, Walser M
The branched-chain amino acid antagonism in chicks.Other primary literatureAnimalActiveThe Journal of nutrition1978
Smith TK, Austic RE
Amino acid derangements in patients with sepsis: treatment with branched chain amino acid rich infusions.Other primary literatureHumanActiveAnnals of surgery1978
Freund HR, Ryan JA Jr, Fischer JE
Branched-chain amino acid transport regulation in mutants blocked in tRNA maturation and transcriptional termination.Other primary literatureUnknownActiveJournal of bacteriology1978
Quay SC, Lawther RP, Hatfield GW, et al.
A new locus (leuK) affecting the regulation of branched-chain amino acid, histidine, and tryptophan biosynthetic enzymes.Other primary literatureUnknownActiveJournal of bacteriology1978
Brown CS, West R, Hilderman RH, et al.
Effect of carnitine on branched-chain amino acid oxidation by liver and skeletal muscle.Other primary literatureAnimalActiveThe American journal of physiology1978
Paul HS, Adibi SA
Branched-chain amino acid aminotransferase in mouse testicular tissue.Other primary literatureAnimalActiveJournal of reproduction and fertility1978
Montamat EE, Moreno J, Blanco A
Isolation and identification of aliphatic short-chain acylcarnitines from beef heart: possible role for carnitine in branched-chain amino acid metabolism.Other primary literatureAnimalActiveProceedings of the National Academy of Sciences of the United States of America1977
Bieber LL, Choi YR
Inhibition of branched-chain amino acid degradation by ketone bodies.Other primary literatureAnimalActiveScandinavian journal of clinical and laboratory investigation1977
Landaas S
Effects of branched-chain amino acid antagonism in the rat on tissue amino acid and keto acid concentrations.Other primary literatureAnimalActiveThe Journal of nutrition1977
Shinnick FL, Harper AE
Role of transport systems in amino acid metabolism: leucine toxicity and the branched-chain amino acid transport systems.Other primary literatureUnknownActiveJournal of bacteriology1977
Quay SC, Dick TE, Oxender DL
Escherichia coli transport mutants lacking binding protein and other components of the branched-chain amino acid transport systems.Other primary literatureUnknownActiveJournal of bacteriology1977
Anderson JJ, Oxender DL
Isozyme patterns of branched-chain amino acid transaminase in human tissues and tumors.Other primary literatureHuman & animalActiveGan1977
Goto M, Shinno H, Ichihara A
Maple syrup urine disease: branched-chain amino acid concentrations and metabolism in cultured human lymphoblasts.Other primary literatureHumanActiveBiochemical genetics1976
Skaper SD, Molden DP, Seegmiller JE
Isolation of mutants lacking branched-chain amino acid transaminase.Other primary literatureUnknownActiveSomatic cell genetics1976
Jones C, Moore EE
Branched-chain amino acid oxidation by isolated rat tissue preparations.Other primary literatureAnimalActiveBiochimica et biophysica acta1976
Shinnick FL, Harper AE
Regulatory role of dietary leucine on plasma branched-chain amino acid levels in young men.Other primary literatureHumanActiveThe Journal of nutrition1976
Hambraeus L, Bilmazes C, Dippel C, et al.
Transport of sugars and amino acids in bacteria. XVII. On the existence and nature of substrate amino acids bound to purified branched chain amino acid-binding proteins of Escherichia coli.Other primary literatureUnknownActiveJournal of biochemistry1976
Amanuma H, Itoh J, Anraku Y
Branched-chain amino acid catabolism in bacteria.ReviewUnknownActiveBacteriological reviews1976
Massey LK, Sokatch JR, Conrad RS
Mapping of two loci affecting the regulation of branched-chain amino acid transport in Escherichia coli K-12.Other primary literatureUnknownActiveJournal of bacteriology1976
Anderson JJ, Quay SC, Oxender DL
Regulation of branched-chain amino acid transport in Escherichia coli.Other primary literatureUnknownActiveJournal of bacteriology1976
Quay SC, Oxender DL
Further studies on the isozyme patterns of branched-chain amino acid transminase in cultured rat hepatocytes.Other primary literatureUnknownActiveGan1976
Tomita Y, Ichihara A, Kuroki T
Isozyme patterns of branched-chain amino acid transminase in cultured Morris hepatoma 7316A.Other primary literatureAnimalActiveGan1976
Tomita Y, Ichihara A, Masuji H, et al.
Regulation of branched-chain amino acid biosynthesis.ReviewUnknownActiveActa microbiologica Academiae Scientiarum Hungaricae1976
Szentirmai A, Horváth I
Regulation of branched-chain amino acid oxidation in isolated muscles, nerves and aortas of rats.Other primary literatureAnimalActiveThe Biochemical journal1975
Buse MG, Jursinic S, Reid SS
Role of leucyl-tRNA synthetase in regulation of branched-chain amino-acid transport.Other primary literatureUnknownActiveProceedings of the National Academy of Sciences of the United States of America1975
Quay SC, Kline EL, Oxender DL
A branched-chain amino acid aminotransferase from the rumen ciliate genus Entodinium.Other primary literatureAnimalActiveThe Journal of protozoology1975
Wakita M, Hoshino S
Isozyme patterns of branched-chain amino acid transaminase during cellular differentiation and carcinogenesis.Other primary literatureAnimalActiveAnnals of the New York Academy of Sciences1975
Ichihara A
Branched-chain amino acid substitutions in the biosynthesis of the antibiotic actinomycin.Other primary literatureUnknownActiveAntimicrobial agents and chemotherapy1975
Yajim T, Mason KT, Kaltz E
Molecular weight, subunit structure, and amino acid composition of the branched chain amino acid aminotransferase of Salmonella typhimurium.Other primary literatureUnknownActiveBiochemistry1974
Lipscomb EL, Horton HR, Armstrong FB
Branched-chain amino acid oxidation in relation to catabolic enzyme activities in rats given a protein-free diet at different stages of development.Other primary literatureAnimalActiveThe British journal of nutrition1974
Sketcher RD, James WP
Transport of sugars and amino acids in bacteria. XII. Substrate specificities of the branched chain amino acid-binding proteins of Escherichia coli.Other primary literatureAnimalActiveJournal of biochemistry1974
Amanuma H, Anraku Y
flrB, a regulatory locus controlling branched-chain amino acid biosynthesis in Salmonella typhimurium.Other primary literatureUnknownActiveJournal of bacteriology1974
Friedberg D, Mikulka TW, Jones J, et al.
Repression of the branched-chain amino acid biosynthetic enzymes in developing conidia and mycelia of Neurospora.Other primary literatureUnknownActiveCanadian journal of biochemistry1974
Jobbágy AJ, Wagner RP
A simple preparative polyacrylamide disc gel electrophoresis apparatus: purification of three branched-chain amino acid binding proteins from Escherichia coli.Other primary literatureUnknownActiveAnalytical biochemistry1973
Furlong CE, Cirakoglu C, Willis RC, et al.
Control of leucine metabolism with special reference to branched-chain amino acid transaminase isozymes.Other primary literatureAnimalActiveAdvances in enzyme regulation1973
Ichihara A, Noda C, Ogawa K
Dietary influences on the activities of enzymes involved in branched-chain amino acid catabolism in the chick.Other primary literatureAnimalActiveThe Journal of nutrition1973
Featherston WR, Horn GW
Transport of sugars and amino acids in bacteria. VI. Changes induced by valine in the branched chain amino acid transport systems of Escherichia coli.Other primary literatureUnknownActiveJournal of biochemistry1973
Anraku Y, Naraki T, Kanzaki S
Common enzymes of branched-chain amino acid catabolism in Pseudomonas putida.Other primary literatureUnknownActiveJournal of bacteriology1973
Martin RR, Marshall VD, Sokatch JR, et al.
Effect of isoleucine, valine, or leucine starvation on the potential for formation of the branched-chain amino acid biosynthetic enzymes.Other primary literatureUnknownActiveJournal of bacteriology1973
Wasmuth JJ, Umbarger HE
Participation of branched-chain amino acid analogues in multivalent repression.Other primary literatureUnknownActiveJournal of bacteriology1973
Wasmuth JJ, Umbarger HE
Cellular differentiation and isozymes of branched-chain amino acid transaminase.Other primary literatureAnimalActiveEnzyme1973
Ichihara A
[Metabolic control of branched-chain amino acid biosynthesis--basis reviewed from fermentative field (author's transl)].ReviewUnknownActiveTanpakushitsu kakusan koso. Protein, nucleic acid, enzyme1973
Kisumi M, Komatsubara S, Chibata I
Regulation of branched chain amino acid transaminase formation during the growth of Pseudomonas fluorescens UK-1.Other primary literatureUnknownActiveActa chemica Scandinavica1972
Puukka M, Lönnberg H, Nurmikko V
[Branched chain amino acid transaminase isozymes in various cancer cells and in the process of oncogenesis].Other primary literatureAnimalActiveSeikagaku. The Journal of Japanese Biochemical Society1971
Ogawa K
Purification and partial characterization of the branched chain amino acid transaminase of Pseudomonas aeruginosa.Other primary literatureUnknownActiveBiochimica et biophysica acta1970
Norton JE, Sokatch JR
Branched chain amino acid aminotransferase. IV. Kinetics of the transamination reactions.Other primary literatureAnimalActiveThe Journal of biological chemistry1970
Taylor RT, Shakespeare V, Jenkins WT
Regulation of branched-chain amino acid biosynthesis in Salmonella typhimurium: isolation of regulatory mutants.Other primary literatureUnknownActiveJournal of bacteriology1969
Calvo JM, Freundlich M, Umbarger HE
Influence of dietary protein levels and hydrocortisone administration on the branched-chain amino acid transaminase activity in rat tissues.Other primary literatureAnimalActiveThe Journal of nutrition1968
Mimura T, Yamada C, Swendseid ME
Branched-chain amino acid catabolism depends on GRXS15 through mitochondrial lipoyl cofactor homeostasisDesign not determinedUnknownUnknown
Moseler A, Kruse I, Maclean AE, et al.
Branched chain amino acid aminotransferase 2 Regulates Ferroptotic Cell Death in Cancer CellsDesign not determinedUnknownUnknown
Wang K, Zhang Z, Hsiang-i T, et al.
Genetically encoded biosensors for branched-chain amino acid metabolism to monitor mitochondrial and cytosolic production of isobutanol and isopentanol in yeastDesign not determinedUnknownUnknown
Zhang Y, Hammer SK, Carrasco-Lopez C, et al.
Branched-Chain Amino Acid Metabolism is Regulated by ERRα in Primary Human Myotubes and is Further Impaired by Glucose Loading in Type 2 DiabetesDesign not determinedUnknownUnknown
Sjögren RJ, Rizo-Roca D, Chibalin AV, et al.
Metabolic flexibility via mitochondrial BCAA carrier SLC25A44 is required for optimal feverDesign not determinedUnknownUnknown
Yoneshiro T, Kataoka N, Walejko JM, et al.
BrnQ-type Branched-chain Amino Acid Transporters Influence Bacillus anthracis Growth and VirulenceDesign not determinedUnknownUnknown
Dutta S, Corsi ID, Bier N, et al.
Mitochondrial Pyruvate Carrier Inhibition Initiates Metabolic Crosstalk to Stimulate Branched Chain Amino Acid CatabolismDesign not determinedUnknownUnknown
Ferguson D, Eichler SJ, Yiew NK, et al.
Impaired BCAA catabolism during adipocyte differentiation decreases glycolytic fluxDesign not determinedUnknownUnknown
Green CR, Wessendorf-Rodriguez KA, Turner R, et al.
Nervous system reduction in branched-chain amino acid metabolism disrupts hippocampal neurogenesis and memoryDesign not determinedUnknownUnknown
Abdi K, Rodriguiz RM, Wetsel WC, et al.
BCAA catabolism drives adipogenesis via an intermediate metabolite and promotes subcutaneous adipose tissue expansion during obesityDesign not determinedUnknownUnknown
Shao J, Liu Y, Zhang X, et al.
Branched chain amino acid synthesis is coupled to TOR activation early in the cell cycle in yeastDesign not determinedUnknownUnknown
Blank HM, Reuse C, Schmidt-Hohagen K, et al.
Enhanced Branched-Chain Amino Acid Metabolism Improves Age-Related Reproduction in C. elegansDesign not determinedUnknownUnknown
Lesnik C, Kaletsky R, Ashraf JM, et al.
Exercise on cytokine responses in males and females: Effect of leucine, HMB and BCAADesign not determinedUnknownUnknown
Brown AD, Grammenou M, Tee CC, et al.
A cell-autonomous mechanism regulates BCAA catabolism in white adipocytes and systemic metabolic balanceDesign not determinedUnknownUnknown
Aguillard AM, Tzeng J, Ferrer I, et al.
Partial suppression of BCAA catabolism as a potential therapy for BCKDK deficiencyDesign not determinedUnknownUnknown
Ohl L, Kuhs A, Pluck R, et al.
Heme biosynthesis regulates BCAA catabolism and thermogenesis in brown adipose tissueDesign not determinedUnknownUnknown
Duerre DJ, Hansen JK, John S, et al.
Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar CarcinomaDesign not determinedUnknownUnknown
Marsh NM, MacEwen MJS, Chea J, et al.
The Soybean Cyst Nematode Effector Cysteine Protease 1 (CPR1) Targets a Mitochondrial Soybean Branched-Chain Amino Acid Aminotransferase (GmBCAT1) for DegradationDesign not determinedUnknownUnknown
Margets A, Foster J, Kumar A, et al.
Contribution of brain intrinsic branched-chain amino acid metabolism in a novel mouse model of maple syrup urine diseaseDesign not determinedUnknownUnknown
Kuhs AC, Ohl L, Thurston T, et al.
Branched-chain amino acid metabolism is a crucial modulator of cellular senescenceDesign not determinedUnknownUnknown
Aramaki Y, Irie K, Obinata H, et al.
Assembly of branched chain amino acid (BCAA) to toxic fibrils may be related to pathogenesis of Maple syrup urine disease (MSUD)Design not determinedUnknownUnknown
Kanth CP, Patel M, Dave R, et al.
Branched-chain amino acid catabolism promotes ovarian cancer cell proliferation via phosphorylation of mTORDesign not determinedUnknownUnknown
Lusk HJ, Haughan MA, Bergsten TM, et al.
ldentify potential feature genes and immune cell infiltration of HIRI based on branched-chain amino acid-related genes by machine learning and experimental validationDesign not determinedUnknownUnknown
Zhao J, Wu M, Li S, et al.
Branched chain amino acid metabolism and microbiome in adolescents with obesity during weight loss therapyDesign not determinedUnknownUnknown
McCann JR, Yang C, Bihlmeyer NA, et al.
Codon-specific ribosome stalling reshapes translational dynamics during branched-chain amino acid starvationDesign not determinedUnknownUnknown
Worpenberg L, Gobet C, Naef F
A nuclear branched-chain amino acid catabolism pathway controls histone propionylation in pancreatic cancerDesign not determinedUnknownUnknown
Demetriadou C, Noji M, Good AL, et al.
Regulation of the branched-chain amino acid pathway and its crosstalk to carbon metabolism in yeastDesign not determinedUnknownUnknown
Escalera-Fanjul X, Bolaji O, Drotleff B, et al.
Iron deficiency drives metabolic adaptation of red pulp macrophages via ferroportin-SYK signaling and BCAA catabolism to enhance erythrophagocytosisDesign not determinedUnknownUnknown
Mandal PK, Mahadeva R, Chouhan K, et al.
Impaired Lung BCAA Metabolism Promotes Ferroptosis and Resultant Pulmonary Arterial Hypertension-Associated HepatopathyDesign not determinedUnknownUnknown
Blake MJ, Hong J, Brownstein A, et al.
Branched-chain amino acid assimilation promotes mixotrophy of ammonia-oxidizing archaeal sponge symbiontsDesign not determinedUnknownUnknown
Glasl B, Kitzinger K, Luter HM, et al.
Contrasting effects of glutamate and branched-chain amino acid metabolism on acid tolerance in a Castellaniella isolate from acidic groundwaterDesign not determinedUnknownUnknown
Goff JL, Durrence KL, Thorgersen MP, et al.
Effect of Age and Sex on BCAA Metabolism in MiceDesign not determinedUnknownUnknown
Mann G, Mora S, Adegoke OAJ
Sex Differences in Cachexia Outcomes and Branched-Chain Amino Acid Metabolism Following Chemotherapy in Aged MiceDesign not determinedUnknownUnknown
Mora S, Mann G, Adegoke OAJ
Differential Branched-Chain Amino Acid Metabolism in Tissues of Tumor-Bearing MiceDesign not determinedUnknownUnknown
Zerrouk M, Delfinis LJ, Perry CG, et al.
Natural variation in C. elegans arsenic toxicity is explained by differences in branched chain amino acid metabolismDesign not determinedUnknownUnknown
Zdraljevic S, Fox BW, Strand C, et al.
Biochemical and structural characterization of a highly active branched-chain amino acid aminotransferase from Pseudomonas sp. for efficient biosynthesis of chiral amino acidsDesign not determinedUnknownUnknown
Zheng X, Cui Y, Li T, et al.
Branched-Chain Amino Acid Metabolic Reprogramming Orchestrates Drug Resistance to EGFR Tyrosine Kinase InhibitorsDesign not determinedUnknownUnknown
Wang Y, Zhang J, Ren S, et al.
Genomic Predictors of BCAA Levels are Associated with Indicators of the Anabolic Response to Protein IntakeDesign not determinedUnknownUnknown
Hall EC, Semenova EA, Bondareva EA, et al.
Association Between Circulating Branched-Chain Amino Acid Levels and Carotid Vulnerable Plaque: A Retrospective Study with Internal ValidationDesign not determinedUnknownUnknown
Zhao L, Tian D, Shi X
Pyridostigmine Protects Against Diabetic Cardiomyopathy by Regulating Gut Microbiota and Branched-Chain Amino Acid Catabolism to Attenuate Mitochondria DysfunctionDesign not determinedUnknownUnknown
Yang Y, Zhao M, He X, et al.
Gut Parabacteroides merdae protects against cardiovascular damage by increasing commensal bacteria-driven branched-chain amino acid catabolismDesign not determinedUnknownUnknown
Qiao S, Liu C, Sun L, et al.
ANGPTL4 Negatively Regulate the Progression of Osteosarcoma by Remodeling Branched-Chain Amino Acid MetabolismDesign not determinedUnknownUnknown
Lin S, Miao Y, Zheng X, et al.
Six-Weeks Very Low-calorie Diet (VLCD) Improves Glycaemic Control Without Reducing Plasma Branched-chain Amino Acids (BCAA) or Keto-Acids (BCKA) in Obese MenDesign not determinedUnknownUnknown
Sayda MH, Abdul-Aziz MH, Gharahdaghi N, et al.
Eravacycline susceptibility was impacted by genetic mutation of 30S ribosome subunits, and branched-chain amino acid transport system II carrier protein, Na/Pi cotransporter family protein in Staphylococcus aureusDesign not determinedUnknownUnknown
Wang Z, Lin Z, Bai B, et al.
Circulating branched-chain amino acid concentrations are associated with skeletal muscle mass and thyroid function in young Japanese menDesign not determinedUnknownUnknown
Tsunekawa K, Matsumoto R, Ushiki K, et al.
A randomized clinical trial of innate immunity restoration by branched-chain amino acid granules in cirrhosis patientsDesign not determinedUnknownUnknown
Chamroonkul N, Rujeerapaiboon N, Sripong P, et al.
Effect of supplemental branched-chain amino acid-enriched nutrients during endoscopic injection sclerotherapy or endoscopic variceal ligation in patients with liver cirrhosisDesign not determinedUnknownUnknown
Kikugawa C, Hiramatsu A, Kinami T, et al.
Circulating Branched-Chain Amino Acid Concentrations are Associated with Skeletal Muscle Mass and Thyroid Function in Young Japanese MenDesign not determinedUnknownUnknown
Tsunekawa K, Matsumoto R, Ushiki K, et al.
PPM1K mediates metabolic disorder of branched-chain amino acid and regulates cerebral ischemia-reperfusion injury by activating ferroptosis in neuronsDesign not determinedUnknownUnknown
Li T, Zhao L, Li Y, et al.
Attenuating Muscle Damage Biomarkers and Muscle Soreness After an Exercise-Induced Muscle Damage with Branched-Chain Amino Acid (BCAA) Supplementation: A Systematic Review and Meta-Analysis with Meta-regressionDesign not determinedUnknownUnknown
Salem A, Maaoui Kb, Jahrami H, et al.
β-aminoisobutyric Acid, a Metabolite of BCAA, Activates the AMPK/Nrf-2 Pathway to Prevent Ferroptosis and Ameliorates Lung Ischemia-Reperfusion InjuryDesign not determinedUnknownUnknown
Zhang Z, Li X, Guo J, et al.
Integrated Multi-Omics Analysis Identifies Disrupted Branched-Chain Amino Acid Catabolism as Causal for SarcopeniaDesign not determinedUnknownUnknown
Li T, Zhao R, Zuo X, et al.
Development of an engineered probiotic for the treatment of branched chain amino acid related metabolic diseasesDesign not determinedUnknownUnknown
Li N, Tucker A, Gao J, et al.
The Effects of Branched Chain Amino Acid Supplement on Kidney Tissue of Exercising RatsDesign not determinedUnknownUnknown
AYDEĞER C, EROĞLU HA
Dietary branched-chain amino acid assessment in broilers from 22 to 35 days of ageDesign not determinedUnknownUnknown
Kidd MT, Poernama F, Wibowo T, et al.
Anti-sarcopenic effect of leucine-enriched branched-chain amino acid supplementation among elderly chronic kidney disease patients: a double-blinded randomized controlled trialDesign not determinedUnknownUnknown
Sunsandee N, Thimachai P, Satirapoj B, et al.
PRSS55 Regulates Energy Homeostasis and BCAA Metabolism via Interacting with BCKDK in Mouse Testes and SpermDesign not determinedUnknownUnknown
Ge H, Shen C, Xiong W, et al.
BCAA was more closely associated with visceral fat area than subcutaneous fat area in patients of type 2 diabetes mellitus：a cross-sectional studyDesign not determinedUnknownUnknown
Cai X, Li W, Wang L, et al.
Integration RNA bulk and single cell RNA sequencing to explore the change of BCAA metabolism-related immune microenvironment and construct prognostic signature in HNSCCDesign not determinedUnknownUnknown
Lu D, Liang Y, Mo T, et al.
Branched-chain amino acid specialization drove diversification within Calditenuaceae (Caldarchaeia) and enables their cultivationDesign not determinedUnknownUnknown
Hedlund B, Lai D, Covington J, et al.
Branched Chained Amino Acid (BCAA)-Induced Migraine without Aura AttackDesign not determinedUnknownUnknown
Sariciek MS, Saricicek AT, Saricicek AT
Significance of serum branched-chain amino acid to tyrosine ratio measurement in athletes with high skeletal muscle massDesign not determinedUnknownUnknown
Tsunekawa K, Matsumoto R, Ushiki K, et al.
A Novel BCAA-catabolism Related Gene Signature for Overall Survival Prediction of Pancreatic CarcinomaDesign not determinedUnknownUnknown
Jiang Z, Zheng J, Liu J, et al.
BCAA catabolism mediates POU2AF1 propionylation to enhance T-ALL developmentDesign not determinedUnknownUnknown
Zheng J, Dan S, Xu Y, et al.
The Effects of Chronic Branched-Chain Amino Acid Supplementation on Running Kinematics: Single Case ResearchDesign not determinedUnknownUnknown
Whiton TK, Sato K, Bazyler C, et al.
hnRNPC Promotes Oral Squamous Cell Carcinoma Progression via m6A-Dependent Stabilization of BCAT1 to Enhance Branched-Chain Amino Acid MetabolismDesign not determinedUnknownUnknown
Zhang Z, Gao X, Han T, et al.
Diagnostic and Prognostic Values of a Branched-chain Amino Acid-associated Gene Signature in Lung CancerDesign not determinedUnknownUnknown
Jiang L, Li Q, Hu Z, et al.
Exploring biomarkers related to branched-chain amino acid metabolism in childhood obesity based on transcriptomics and experimental verificationDesign not determinedUnknownUnknown
Zhang H, Lei Y, Guan L, et al.
Metabolomic impacts of branched-chain amino acid supplementation during endurance exercise: a crossover studyDesign not determinedUnknownUnknown
Peach JT, Funk D, Frothingham L, et al.
Single-Cell Dissection of BCAA Metabolism Unveils ACAT1-Dependent CS Acetylation as a Metabolic Checkpoint for Immunosuppression in Prostate CancerDesign not determinedUnknownUnknown
Huang F, Li M, Ma X
Production of Butyrate and Branched Chain Amino Acid Catabolic Byproducts by CHO Cells in Fed-batch Culture Enhances their Specific ProductivityDesign not determinedUnknownUnknown
Harrington C, Kalomeris T, Jacobs M, et al.
Genetic influence of BCAA metabolism on type 2 diabetes and coronary artery disease, independent of traditional risk factorsDesign not determinedUnknownUnknown
Nakamura S, Koido M, He Y, et al.
Disruption of PI3K-OxPhos Coupling by Trehalose Drives a BCAA-to-Lipid Metabolic Switch in Hormone-Receptor–Positive Breast CancerDesign not determinedUnknownUnknown
Singh T, Kaur P, Munshi A, et al.
Niche-specific contribution of the branched-chain amino acid biosynthesis protein IlvD in Streptococcus pneumoniae infectionDesign not determinedUnknownUnknown
Kumar S, Green AE, Lorenz LJ, et al.
Investigations related to branched-chain amino acid metabolismDesign not determinedUnknownUnknown
Lee ER
Alanine formation and branched-chain amino acid metabolism by rat skeletal muscleDesign not determinedUnknownUnknown
Duff DA
Compound branched chain amino acid injectionDesign not determinedUnknownUnknown
MASATO FURUKAWA
Method for preparing solid beverage comprising branched chain amino acidDesign not determinedUnknownUnknown
HOUZENG BAI, YING JIAO, QIGENG LI, et al.
BRANCHED CHAIN AMINO ACID BIOSYNTHETIC ENZYMESDesign not determinedUnknownUnknown
ALLEN Stephen M., FALCO Saverio Carl, HITZ William D.
TABLET CONTAINING BRANCHED CHAIN AMINO ACID AND PROCESS FOR PRODUCING THE SAMEDesign not determinedUnknownUnknown
HARA TAKAHIRO, KIMURA MASAO, SAKAI YASUSHI
Promoter-activity modulation for branched-chain amino acid productionDesign not determinedUnknownUnknown
ELISAKOVA VERONIKA, HOLATKO JIRI, NESVERA JAN, et al.
TABLET CONTAINING BRANCHED CHAIN AMINO ACID AND PROCESS FOR PRODUCING THE SAMEDesign not determinedUnknownUnknown
HARA TAKAHIRO, KIMURA MASAO, SAKAI YASUSHI
BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE GENE AND USE THEREOFDesign not determinedUnknownUnknown
NAKAO YOSHIHIRO, KODAMA YUKIKO, SHIMONAGA TOMOKO
Tablet Comprising Branched Chain Amino Acid and Method for Producing the SameDesign not determinedUnknownUnknown
HARA TAKAHIRO, KIMURA MASAO, SAKAI YASUSHI
Branched Chain Amino Acid ChelateDesign not determinedUnknownUnknown
BASTIAN ERIC D, HAGEN BRENT P
Branched-chain amino acid aminotransferase gene and use thereofDesign not determinedUnknownUnknown
NAKAO YOSHIHIRO, KODAMA YUKIKO, SHIMONAGA TOMOKO
TABLET CONTAINING BRANCHED CHAIN AMINO ACID AND PROCESS FOR PRODUCING THE SAMEDesign not determinedUnknownUnknown
HARA Takahiro, KIMURA Masao, SAKAI Yasushi
BRANCHED-CHAIN AMINO ACID AMINOTRANSFERASE GENE AND USE THEREOFDesign not determinedUnknownUnknown
NAKAO Yoshihiro, KODAMA Yukiko, SHIMONAGA Tomoko
BRANCHED CHAIN AMINO ACID CHELATEDesign not determinedUnknownUnknown
BASTIAN ERIC, HAGEN BRENT
ORALLY ADMINISTRABLE FORMULATION CONTAINING BRANCHED CHAIN AMINO ACIDDesign not determinedUnknownUnknown
ABURATANI SATOSHI, ONOSHITA TOMOYA, MATSUSHITA TAKASHI, et al.
BRANCHED CHAIN AMINO ACID BIOSYNTHETIC ENZYMESDesign not determinedUnknownUnknown
FALCO Saverio Carl, ALLEN Stephen M., HITZ William D.
Hyperpolarized α-keto[1-13C]isocaproate as a 13C magnetic resonance spectroscopic agent for profiling branched chain amino acid metabolism in tumorsReviewUnknownActive
Shan L