Arginine / Citrulline Disposition in Humans Citrulline

Development of a generic physiologically based pharmacokinetic model to predict clinical pharmacokinetics and assess drug-drug interaction risks for valine-citrulline-monomethyl auristatin E-based antibody-drug conjugates.

Drug metabolism and disposition: the biological fate of chemicals2026Shen C, Wang R, Yan J, et al.

Study designOther primary literature

SubjectHuman

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Study design: Other primary literature
Subject: Human
Publication year: 2026
Source: doi.org
Abstract display: Not reproduced here
Publication status: Active
Status checked: 17 Aug 2026
Collected: 13 Aug 2026
Freshness: Current
Review stage: Automated
Record status: Published

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Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

ATP Binding Cassette Transporter, Subfamily B, Member 1CitrullineCytochrome P-450 CYP3A InducersDrug InteractionsHumansImmunoconjugatesModels, BiologicalOligopeptides

DOI 10.1016/j.dmd.2026.100289

PMID 42066734

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