Bibliographic records for Arginine / Citrulline Disposition in Humans. 73 records, version 2026-08-17.1, reference date 2026-08-17, 100 per page.
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Development of a generic physiologically based pharmacokinetic model to predict clinical pharmacokinetics and assess drug-drug interaction risks for valine-citrulline-monomethyl auristatin E-based antibody-drug conjugates.Scholarly articleOther literature / recordsHumanActiveDrug metabolism and disposition: the biological fate of chemicals2026
Shen C, Wang R, Yan J, et al.
L-Citrulline in Maternal-Fetal and Neonatal Health: Metabolic Mechanisms and Emerging Therapeutic Applications.Scholarly articleReviewHumanActiveNutrients2026
Collins-Smith A, Jain S, Jain S
L-Arginine and Nitric Oxide in Vascular Regulation-Experimental Findings in the Context of Blood Donation.Scholarly articleReviewHuman & animalActiveNutrients2025
Kurhaluk N, Tkaczenko H
Divergent roles of red cell arginase in humans and mice: RBC Arg1 KO mice show preserved systemic l-arginine bioavailability and infarct size in vivo.Scholarly articleOther literature / recordsHuman & animalActiveRedox biology2025
Heuser SK, Li J, Li Z, et al.
The Discovery of Selective Protein Arginine Methyltransferase 5 Inhibitors in the Management of β-Thalassemia through Computational Methods.Scholarly articleOther literature / recordsHumanActiveMolecules (Basel, Switzerland)2024
Pokharel B, Ravikumar Y, Rathinavel L, et al.
Low global arginine bioavailability: a common phenomenon in pulmonary hypertension.Other recordOther literature / recordsHumanActiveAmerican journal of physiology. Lung cellular and molecular physiology2024
Hatabah D, De Marco T, McGlothlin DP, et al.
Lower Arginine Bioavailability, Increased FeNO Levels, and Airway Resistance on Impulse Oscillometry Are Characteristics of Asthma in Children and Young Adults with Sickle Cell Disease.Scholarly articleOther literature / recordsHumanActiveMedicina (Kaunas, Lithuania)2024
Ozhan AK, Arikoglu T, Er M, et al.
Improving the Bioavailability and Efficacy of Coenzyme Q10 on Alzheimer's Disease Through the Arginine Based Proniosomes.Scholarly articleOther literature / recordsHuman & animalActiveJournal of pharmaceutical sciences2023
Ergin AD, Üner B, Balcı Ş, et al.
Barriers to the Intestinal Absorption of Four Insulin-Loaded Arginine-Rich Nanoparticles in Human and Rat.Scholarly articleOther literature / recordsHuman & animalActiveACS nano2022
Lundquist P, Khodus G, Niu Z, et al.
Design, Synthesis and Biological Evaluation of Novel and Potent Protein Arginine Methyltransferases 5 Inhibitors for Cancer Therapy.Scholarly articleOther literature / recordsHumanActiveMolecules (Basel, Switzerland)2022
Tang Y, Huang S, Chen X, et al.
Excellent Multiphoton Excitation Fluorescence with Large Multiphoton Absorption Cross Sections of Arginine-Modified Gold Nanoclusters for Bioimaging.Scholarly articleOther literature / recordsHumanActiveACS applied materials & interfaces2022
Wei Z, Pan Y, Hou G, et al.
Effect of food sources of nitrate, polyphenols, L-arginine and L-citrulline on endurance exercise performance: a systematic review and meta-analysis of randomised controlled trials.Scholarly articleMeta-analysisHumanActiveJournal of the International Society of Sports Nutrition2021
d'Unienville NMA, Blake HT, Coates AM, et al.
Acute L-Citrulline Supplementation Increases Nitric Oxide Bioavailability but Not Inspiratory Muscle Oxygenation and Respiratory Performance.Scholarly articleOther literature / recordsHumanActiveNutrients2021
Theodorou AA, Zinelis PT, Malliou VJ, et al.
l-Arginine/l-lysine functionalized chitosan-casein core-shell and pH-responsive nanoparticles: fabrication, characterization and bioavailability enhancement of hydrophobic and hydrophilic bioactive compounds.Scholarly articleOther literature / recordsHumanActiveFood & function2020
Du Z
, Liu J
, Zhang H
, et al.
Altered Bioavailability of Nitric Oxide and L-Arginine Is a Key Determinant of Endothelial Dysfunction in Preeclampsia.Scholarly articleOther literature / recordsHumanActiveBioMed research international2020
Tashie W, Fondjo LA, Owiredu WKBA, et al.
Enhanced Fluoride Bioavailability with Incorporation of Arginine in Child Dentifrices.Scholarly articleOther literature / recordsHumanActiveThe Journal of clinical pediatric dentistry2020
Bijle MN, Tsoi J, Ekambaram M, et al.
Lack of relationship between fasting plasma citrulline and glucose absorption: do not underestimate the role of the failing kidney!Other recordOther literature / recordsHumanActiveCritical care (London, England)2019
Honore PM, De Bels D, Gallerani A, et al.
Aspergillus nidulans thermostable arginine deiminase-Dextran conjugates with enhanced molecular stability, proteolytic resistance, pharmacokinetic properties and anticancer activity.Scholarly articleOther literature / recordsHuman & animalActiveEnzyme and microbial technology2019
El-Sayed ASA, Shindia AA, Zeid AAA, et al.
Metabolites of the Nitric Oxide (NO) Pathway Are Altered and Indicative of Reduced NO and Arginine Bioavailability in Patients with Cardiometabolic Diseases Complicated with Chronic Wounds of Lower Extremities: Targeted Metabolomics Approach (LC-MS/MS).Scholarly articleOther literature / recordsHumanActiveOxidative medicine and cellular longevity2019
Krzystek-Korpacka M, Wiśniewski J, Fleszar MG, et al.
Global arginine bioavailability ratio is decreased in patients with major depressive disorder.Scholarly articleOther literature / recordsHumanActiveJournal of affective disorders2018
Ali-Sisto T, Tolmunen T, Viinamäki H, et al.
Drastic decrease of global l-arginine bioavailability during orthotopic liver transplantation: A matter of ATP deficiency of the graft?Other recordOther literature / recordsHumanActiveNitric oxide : biology and chemistry2018
Tsikas D, Hanff E, Becker T
Arginine bioavailability and endothelin-1 system in the regulation of vascular function of umbilical vein endothelial cells from intrauterine growth restricted newborns.Scholarly articleOther literature / recordsHumanActiveNutrition, metabolism, and cardiovascular diseases : NMCD2018
He Q, Liu X, Zhong Y, et al.
Malaria in pregnancy alters l-arginine bioavailability and placental vascular development.Scholarly articleOther literature / recordsHuman & animalActiveScience translational medicine2018
McDonald CR, Cahill LS, Gamble JL, et al.
Enhanced In Vitro Zinc Bioavailability through Rational Design of a Dual Zinc plus Arginine Dentifrice.Scholarly articleOther literature / recordsHumanActiveThe Journal of clinical dentistry2018
Manus LM, Daep CA, Begum-Gafur R, et al.
Potential of single cationic amino acid molecule "Arginine" for stimulating oral absorption of insulin.Scholarly articleOther literature / recordsHuman & animalActiveInternational journal of pharmaceutics2017
Kamei N, Khafagy ES, Hirose J, et al.
GC-MS and GC-MS/MS measurement of ibuprofen in 10-μL aliquots of human plasma and mice serum using [α-methylo-2H3]ibuprofen after ethyl acetate extraction and pentafluorobenzyl bromide derivatization: Discovery of a collision energy-dependent H/D isotope effect and pharmacokinetic application to inhaled ibuprofen-arginine in mice.Scholarly articleOther literature / recordsHuman & animalActiveJournal of chromatography. B, Analytical technologies in the biomedical and life sciences2017
Tsikas D, Kayacelebi AA, Hanff E, et al.
Small Molecule Inhibitors of Protein Arginine Methyltransferases.Scholarly articleReviewHuman & animalActiveExpert opinion on investigational drugs2016
Hu H, Qian K, Ho MC, et al.
Global arginine bioavailability, a marker of nitric oxide synthetic capacity, is decreased in PTSD and correlated with symptom severity and markers of inflammation.Scholarly articleOther literature / recordsHumanActiveBrain, behavior, and immunity2016
Bersani FS, Wolkowitz OM, Lindqvist D, et al.
Nitric Oxide-Dependent Endothelial Dysfunction and Reduced Arginine Bioavailability in Plasmodium vivax Malaria but No Greater Increase in Intravascular Hemolysis in Severe Disease.Scholarly articleOther literature / recordsHumanActiveThe Journal of infectious diseases2016
Barber BE, William T, Grigg MJ, et al.
Pharmacokinetic-Pharmacodynamic Model for the Effect of l-Arginine on Endothelial Function in Patients with Moderately Severe Falciparum Malaria.Scholarly articleObservational studyHumanActiveAntimicrobial agents and chemotherapy2016
Brussee JM, Yeo TW, Lampah DA, et al.
The effects of linagliptin on endothelial function and global arginine bioavailability ratio in coronary artery disease patients with early diabetes: study protocol for a randomized controlled trial.Scholarly articleRandomized controlled trialHumanActiveTrials2016
Tripolt NJ, Aberer F, Riedl R, et al.
Effects of Dietary l-Arginine on Nitric Oxide Bioavailability in Obese Normotensive and Obese Hypertensive Subjects.Scholarly articleOther literature / recordsHumanActiveNutrients2016
Giam B, Kuruppu S, Head GA, et al.
Investigation of a potential pharmacokinetic interaction between perindopril arginine and amlodipine when administered as a single perindopril/amlodipine fixed-dose combination tablet in healthy Chinese male volunteers.Scholarly articleRandomized controlled trialHumanActiveInternational journal of clinical pharmacology and therapeutics2016
Zheng X, Liu T, Chen X, et al.
Simultaneous determination of citrulline and arginine in human blood plasma by capillary electrophoresis with ultraviolet absorption detection.Scholarly articleOther literature / recordsHumanActiveJournal of separation science2014
Forteschi M, Sotgia S, Pintus G, et al.
Oral supplementation with a combination of L-citrulline and L-arginine rapidly increases plasma L-arginine concentration and enhances NO bioavailability.Scholarly articleOther literature / recordsHuman & animalActiveBiochemical and biophysical research communications2014
Morita M, Hayashi T, Ochiai M, et al.
Diminished global arginine bioavailability as a metabolic defect in chronic systolic heart failure.Scholarly articleOther literature / recordsHumanActiveJournal of cardiac failure2013
Tang WH, Shrestha K, Wang Z, et al.
Arginine vasopressin-dependent and AVP-independent mechanisms of renal fluid absorption during thirsting despite glucocorticoid-mediated vasopressin suppression.Scholarly articleOther literature / recordsHumanActiveClinical endocrinology2013
Ufer F, Diederich S, Pedersen EB, et al.
Multifactorial risk factor intervention in patients with Type 2 diabetes improves arginine bioavailability ratios.Scholarly articleOther literature / recordsHumanActiveDiabetic medicine : a journal of the British Diabetic Association2012
Tripolt NJ, Meinitzer A, Eder M, et al.
Arginine bioavailability ratios are associated with cardiovascular mortality in patients referred to coronary angiography.Scholarly articleOther literature / recordsHumanActiveAtherosclerosis2011
Sourij H, Meinitzer A, Pilz S, et al.
Global arginine bioavailability in Tanzanian sickle cell anaemia patients at steady-state: a nested case control study of deaths versus survivors.Scholarly articleOther literature / recordsHumanActiveBritish journal of haematology2011
Cox SE, Makani J, Komba AN, et al.
Arginine metabolism and nitric oxide bioavailability in sickle cell disease.Scholarly articleOther literature / recordsHumanActiveJournal of pediatric hematology/oncology2010
Jain S, Gladwin MT
Dysregulation of L-arginine metabolism and bioavailability associated to free plasma heme.Scholarly articleOther literature / recordsHumanActiveAmerican journal of physiology. Cell physiology2010
Omodeo-Salè F, Cortelezzi L, Vommaro Z, et al.
Diminished global arginine bioavailability and increased arginine catabolism as metabolic profile of increased cardiovascular risk.Scholarly articleOther literature / recordsHumanActiveJournal of the American College of Cardiology2009
Tang WH, Wang Z, Cho L, et al.
Increasing plasma glutamine in postoperative patients fed an arginine-rich immune-enhancing diet--a pharmacokinetic randomized controlled study.Scholarly articleRandomized controlled trialHumanActiveCritical care medicine2009
Loï C, Zazzo JF, Delpierre E, et al.
Mechanisms and kinetics of citrulline uptake in a model of human intestinal epithelial cells.Scholarly articleOther literature / recordsHumanActiveClinical nutrition (Edinburgh, Scotland)2008
Bahri S, Curis E, El Wafi FZ, et al.
Dose-ranging effects of citrulline administration on plasma amino acids and hormonal patterns in healthy subjects: the Citrudose pharmacokinetic study.Scholarly articleRandomized controlled trialHumanActiveThe British journal of nutrition2008
Moinard C, Nicolis I, Neveux N, et al.
Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism.Scholarly articleRandomized controlled trialHumanActiveBritish journal of clinical pharmacology2008
Schwedhelm E, Maas R, Freese R, et al.
Citrulline blood levels as indicators of residual intestinal absorption in patients with short bowel syndrome.Scholarly articleOther literature / recordsHumanActiveAnnals of nutrition & metabolism2008
Santarpia L, Catanzano F, Ruoppolo M, et al.
Fasting plasma citrulline concentrations do not reflect intestinal absorption capacity.Other recordOther literature / recordsHumanActiveJPEN. Journal of parenteral and enteral nutrition2008
Peters JH, Mulder CJ, van Bodegraven AA
Poor diagnostic accuracy of a single fasting plasma citrulline concentration to assess intestinal energy absorption capacity.Scholarly articleOther literature / recordsHumanActiveThe American journal of gastroenterology2007
Peters JH, Wierdsma NJ, Teerlink T, et al.
[Serum citrulline: a potential marker for intestinal epithelial mass and absorption capacity in short bowel syndrome patients].Scholarly articleOther literature / recordsHumanActiveZhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery2007
Gong JF, Zhu WM, Li N, et al.
Impaired nitric oxide bioavailability and L-arginine reversible endothelial dysfunction in adults with falciparum malaria.Scholarly articleOther literature / recordsHuman & animalActiveThe Journal of experimental medicine2007
Yeo TW, Lampah DA, Gitawati R, et al.
Impaired flow-mediated dilation with age is not explained by L-arginine bioavailability or endothelial asymmetric dimethylarginine protein expression.Scholarly articleOther literature / recordsHumanActiveJournal of applied physiology (Bethesda, Md. : 1985)2007
Gates PE, Boucher ML, Silver AE, et al.
Adverse effects of cigarette smoke on NO bioavailability: role of arginine metabolism and oxidative stress.Scholarly articleOther literature / recordsHuman & animalActiveHypertension (Dallas, Tex. : 1979)2006
Zhang WZ, Venardos K, Chin-Dusting J, et al.
Serum citrulline is a simple quantitative marker for small intestinal enterocytes mass and absorption function in short bowel patients.Scholarly articleOther literature / recordsHumanActiveThe Journal of surgical research2005
Jianfeng G, Weiming Z, Ning L, et al.
An oral yohimbine/L-arginine combination (NMI 861) for the treatment of male erectile dysfunction: a pharmacokinetic, pharmacodynamic and interaction study with intravenous nitroglycerine in healthy male subjects.Scholarly articleRandomized controlled trialHumanActiveBritish journal of clinical pharmacology2005
Kernohan AF, McIntyre M, Hughes DM, et al.
Diminished L-arginine bioavailability in hypertension.Scholarly articleOther literature / recordsHuman & animalActiveClinical science (London, England : 1979)2004
Moss MB, Brunini TM, Soares De Moura R, et al.
Decreased arginine bioavailability and increased serum arginase activity in asthma.Scholarly articleOther literature / recordsHumanActiveAmerican journal of respiratory and critical care medicine2004
Morris CR, Poljakovic M, Lavrisha L, et al.
L-arginine-induced vasodilation in healthy humans: pharmacokinetic-pharmacodynamic relationship.Scholarly articleRandomized controlled trialHumanActiveBritish journal of clinical pharmacology1998
Bode-Böger SM, Böger RH, Galland A, et al.
Preliminary pharmacokinetic study of ibuprofen enantiomers after administration of a new oral formulation (ibuprofen arginine) to healthy male volunteers.Scholarly articleRandomized controlled trialHumanActiveChirality1997
Fornasini G, Monti N, Brogin G, et al.
Effect of L-arginine on intestinal water and sodium absorption.Other recordOther literature / recordsHuman & animalActiveGut1997
Holdsworth CD, Hellier MD
Bioavailability of 1-deamino-8-D-arginine vasopressin with an enzyme inhibitor (aprotinin) from the small intestine in healthy volunteers.Scholarly articleOther literature / recordsHumanActiveEuropean journal of clinical pharmacology1996
Fjellestad-Paulsen A, d'Agay-Abensour L, Höglund P, et al.
Absolute bioavailability of an aqueous solution of 1-deamino-8-D-arginine vasopressin from different regions of the gastrointestinal tract in man.Scholarly articleOther literature / recordsHumanActiveEuropean journal of clinical pharmacology1993
d'Agay-Abensour L, Fjellestad-Paulsen A, Höglund P, et al.
Elevated plasma concentration of arginine-vasopressin in renal insufficiency is not caused by nonspecific binding of metabolic breakdown products.Other recordOther literature / recordsHumanActiveNephron1991
Bald M, Gross P, Rascher W
Pharmacokinetic study of butyric acid administered in vivo as sodium and arginine butyrate salts.Scholarly articleOther literature / recordsHuman & animalActiveClinica chimica acta; international journal of clinical chemistry1989
Daniel P, Brazier M, Cerutti I, et al.
Arginine vasopressin in children with moderately impaired renal function. Plasma concentration and its relationship to urinary clearance.Scholarly articleOther literature / recordsHumanActiveContributions to nephrology1988
Bald M, Rascher W, Schärer K
Plasma concentration and urinary excretion of arginine vasopressin in children with moderately impaired renal function.Scholarly articleOther literature / recordsHumanActiveChild nephrology and urology1988
Bald M, Rascher W, Schärer K
Plasma concentration and urinary excretion of arginine-vasopressin in primary aldosteronism during the fluid deprivation tests.Scholarly articleOther literature / recordsHumanActiveExperimental and clinical endocrinology1983
Horký K, Sramková J, Widimsky J Jr, et al.
Intestinal absorption in lysinuric protein intolerance: impaired for diamino acids, normal for citrulline.Scholarly articleOther literature / recordsHumanActiveGut1980
Rajantie J, Simell O, Perheentupa J
[Absorption and oxidation rate of arginine and malate (author's transl)].Scholarly articleOther literature / recordsHumanActiveLeber, Magen, Darm1978
Herbetz L, Adrian M, Bongers R, et al.
Jejunal and ileal absorption of dibasic amino acids and an arginine-containing dipeptide in cystinuria.Scholarly articleOther literature / recordsHumanActiveGastroenterology1975
Silk DB, Perrett D, Clark ML
Intestinal absorption of an arginine-containing peptide in cystinuria.Scholarly articleOther literature / recordsHumanActiveGut1972
Asatoor AM, Harrison BD, Milne MD, et al.
Intestinal absorption of L-arginine and L-lysine in familial protein intolerance.Scholarly articleOther literature / recordsHumanActiveAnnales paediatriae Fenniae1968
Kekomäki M