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Caffeine-induced fetal rat over-exposure to maternal glucocorticoid and histone methylation of liver IGF-1 might cause skeletal growth retardation.

Toxicology letters2012Tan Y, Liu J, Deng Y, et al.
Study designOther primary literature
SubjectAnimal

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Study design
Other primary literature
Subject
Animal
Publication year
2012
Source
doi.org
Abstract display
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Publication status
Active
Status checked
17 Aug 2026
Collected
3 Aug 2026
Freshness
Current
Review stage
Automated
Record status
Published

Abstract

cc by 以外(cc by-nc / cc by-nc-nd / NONE 等)は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

AnimalsCaffeineCentral Nervous System StimulantsFemaleFemurFetal DevelopmentFetal Growth RetardationFetal WeightGene Expression Regulation, DevelopmentalGlucocorticoidsGrowth PlateHistonesInsulin-Like Growth Factor ILiverMaleMaternal ExposureMaternal-Fetal ExchangeMethylationPregnancyRNA, MessengerRatsRats, Wistar

DOI 10.1016/j.toxlet.2012.09.007

PMID 22995397

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