Long-term nitric oxide deficiency causes muscarinic supersensitivity and reduces beta(3)-adrenoceptor-mediated relaxation, causing rat detrusor overactivity.

British journal of pharmacology2008Mónica FZ, Bricola AA, Báu FR, et al.

Study designOther primary literature

SubjectAnimal

Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

Adrenergic beta-3 Receptor AgonistsAdrenergic beta-AgonistsAnimalsCarbacholInositol PhosphatesMaleMuscarinic AgonistsMuscle ContractionMuscle, SmoothNG-Nitroarginine Methyl EsterNitric OxideNitric Oxide SynthaseRatsRats, WistarReceptors, Adrenergic, beta-3Receptors, MuscarinicUrinary BladderUrinary Bladder, Overactive

DOI 10.1038/bjp.2008.39

PMID 18297104

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