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Deceptive Caffeine Shows Limited Impact on Short-Term Neuromuscular Performance.

Nutrients2026Valero F, Viudez CJ, Calle S, et al.
Study designRandomized controlled trial
SubjectHuman

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Study design
Randomized controlled trial
Subject
Human
Publication year
2026
Source
doi.org
Abstract display
Shown here
Publication status
Active
Status checked
17 Aug 2026
Collected
3 Aug 2026
Freshness
Current
Review stage
Automated
Record status
Published

Abstract

Background: Deceptive caffeine ingestion has shown inconsistent effects as an ergogenic aid for short-term exercises. Objective: Therefore, the aim of this study was to evaluate the potential placebo effect of deceptive caffeine ingestion on short-term performance during countermovement and repeated-jump tests, as well as bench press throw and bench press-to-failure assessments, and to document any associated side effects. Methods: A repeated, randomized, and counterbalanced design was implemented to compare the effects of ingesting a placebo claimed to be caffeine with a control condition in which no substance was consumed. Twenty-five physically active young adults (17 men and 8 women) completed a countermovement jump (CMJ) test, a 15 s repeated-jump test, bench press throws at 25%, 50%, and 75% of 1RM, and a bench press-to-failure test at 75% of 1RM and also completed a questionnaire regarding potential side effects. Results: Performance was similar between the placebo and control in the CMJ (38.1 ± 6.8 vs. 37.5 ± 6.8 cm; p = 0.225; d = 0.25) and in the 15 s repeated-jump test (p > 0.05; trivial-small effects). In the bench press throw, propulsive mean velocity did not differ at 25% 1RM (p = 0.296; d = 0.23) or 50% 1RM (p = 0.626; d = 0.10). However, deceptive caffeine ingestion increased propulsive mean velocity at 75% 1RM (0.500 ± 0.131 vs. 0.480 ± 0.131 m/s; p = 0.024; d = 0.48) and increased repetitions to failure at the same load (11.9 ± 3.7 vs. 11.0 ± 3.1; p = 0.047; d = 0.42). Mean velocity during the first 3 repetitions tended to be higher with the placebo (p = 0.064; d = 0.39), while final repetitions were similar (p = 0.469; d = 0.15). The most common side effects were increased activeness (34.8%) and nervousness (17.4%). Conclusions: In summary, deceptive caffeine ingestion had minimal impact on jump and ballistic bench press performance in physically active individuals. However, repetitions to failure were improved by ≈1 repetition (+8.2%). These findings suggest that the placebo effect of caffeine is unlikely to serve as a reliable strategy for enhancing short-term exercise performance.

MeSH

AdultAthletic PerformanceCaffeineDeceptionExercise TestFemaleHumansMaleMuscle StrengthMuscle, SkeletalPerformance-Enhancing SubstancesPlacebo EffectYoung Adult

DOI 10.3390/nu18020295

PMID 41599908

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