Research on non-formulated ingredients
p53–ASS1–Akt Pathway
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Role of genetic factors in imatinib resistance of chronic myeloid leukemia: P53, RB1, ASS1 gene deletions, and chromosome 8 hyperdiploidy.Other primary literatureHumanActivePathology, research and practice2025
Hasanova A, Asadov C, Shirinova A, et al.
Sestrin3 confers resistance to recombinant human arginase in small cell lung cancer by activating Akt/mTOR/ASS1 axis.Other primary literatureHuman & animalActivePloS one2025
Zhang Z, Lin Z, Li W, et al.
β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.Other primary literatureHumanActiveFree radical biology & medicine2024
Wang H, Liu J, Zhang Z, et al.
ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response.Other primary literatureHumanCorrectedNature metabolism2024
Lim LQJ, Adler L, Hajaj E, et al.
Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p53.Other primary literatureHuman & animalActiveScience advances2017
Miyamoto T, Lo PHY, Saichi N, et al.