β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.

Free radical biology & medicine2024Wang H, Liu J, Zhang Z, et al.

Study designOther primary literature

SubjectHuman

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Study design: Other primary literature
Subject: Human
Publication year: 2024
Source: doi.org
Abstract display: Not reproduced here
Publication status: Active
Status checked: 17 Aug 2026
Collected: 13 Aug 2026
Freshness: Current
Review stage: Automated
Record status: Published

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Abstract

cc by 以外（cc by-nc / cc by-nc-nd / NONE 等）は抄録を再掲しない。DOI/PMID へのリンクのみ表示する。

MeSH

AntioxidantsApoptosisArgininosuccinate SynthaseFemaleHumansKelch-Like ECH-Associated Protein 1NF-E2-Related Factor 2Ovarian NeoplasmsPTEN PhosphohydrolasePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReactive Oxygen SpeciesSignal TransductionSitosterolsUbiquitins

DOI 10.1016/j.freeradbiomed.2024.02.004

PMID 38364944

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