Spinosyn A derivatives as ASS1 activators and tumor inhibitors.学術論文その他の文献・記録ヒト有効な記録Bioorganic & medicinal chemistry letters2026
Huang XY, Liu XH, Xu N, et al.
Arginine restriction exploits DNMT3B-ASS1-driven arginine auxotrophy and mTORC1-suppressed autophagy to overcome niraparib resistance in ovarian cancer.学術論文その他の文献・記録ヒト・動物 併記有効な記録Cancer letters2026
Wang H, Wang X, Zhang W, et al.
DDIT3, OTUB2, and ASS1 regulate arginine biosynthesis in colorectal cancer cells under arginine deficiency.学術論文その他の文献・記録ヒト・動物 併記有効な記録Cell reports2026
Li M, Zhang J, Zhang H, et al.
ASS1 Promotes Colorectal Cancer Immune Evasion Through CPT1A-Mediated S100A10 Succinylation.学術論文その他の文献・記録ヒト・動物 併記有効な記録Frontiers in bioscience (Landmark edition)2026
Sun L, Fu D, Zhang H
ZFPL1 Promotes Colorectal Cancer Progression by Stabilizing ASS1 to Drive the Urea Cycle and M2 Macrophage-Mediated Metastatic Colonization.学術論文その他の文献・記録ヒト・動物 併記有効な記録Advanced science (Weinheim, Baden-Wurttemberg, Germany)2025
Qian X, Xie C, Zhang B, et al.
ASS1 enhances anoikis resistance via AMPK/CPT1A-mediated fatty acid metabolism in ovarian cancer.学術論文その他の文献・記録ヒト・動物 併記有効な記録Cancer letters2025
Feng X, Ji Z, Fan X, et al.
Advances in the impact of ASS1 dysregulation on metabolic reprogramming of tumor cells.学術論文レビューヒト・動物 併記有効な記録Cellular signalling2025
Xia J, Liu W, Ni Y, et al.
ASS1 inhibits liver cancer by promoting CAD ubiquitination and reversing the urea cycle and pyrimidine synthesis imbalance.学術論文その他の文献・記録ヒト・動物 併記有効な記録Hepatology communications2025
Ming Z, Luo T, Zou Z, et al.
Etoposide-induced protein 2.4 homolog promotes argininosuccinate synthase 1 and cancer cell survival upon arginine deprivation.学術論文その他の文献・記録ヒト有効な記録Cellular & molecular biology letters2025
Vo VTA, Tran LN, Bui TT, et al.
Sestrin3 confers resistance to recombinant human arginase in small cell lung cancer by activating Akt/mTOR/ASS1 axis.学術論文その他の文献・記録ヒト・動物 併記有効な記録PloS one2025
Zhang Z, Lin Z, Li W, et al.
Evodiamine Inhibits Colorectal Cancer by Downregulating ASS1 via Wnt/β-Catenin/c-MYC Pathway to Block Arginine Synthesis.学術論文その他の文献・記録未確定有効な記録Pharmaceuticals (Basel, Switzerland)2025
Wang H, Deng H, He J, et al.
LM2I leads to CAD ubiquitination and liver cancer suppression through activation of ASS1.学術論文その他の文献・記録ヒト・動物 併記有効な記録Acta biochimica et biophysica Sinica2025
Ming Z, Luo T, Zou Z, et al.
β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.学術論文その他の文献・記録ヒト有効な記録Free radical biology & medicine2024
Wang H, Liu J, Zhang Z, et al.
ASS1 inhibits triple-negative breast cancer by regulating PHGDH stability and de novo serine synthesis.学術論文その他の文献・記録ヒト・動物 併記有効な記録Cell death & disease2024
Luo W, Zou Z, Nie Y, et al.
ASS1-Mediated Reductive Carboxylation of Cytosolic Glutamine Confers Ferroptosis Resistance in Cancer Cells.学術論文その他の文献・記録ヒト有効な記録Cancer research2023
Hu Q, Dai J, Zhang Z, et al.
A pan-cancer analysis of the role of argininosuccinate synthase 1 in human tumors.学術論文その他の文献・記録未確定有効な記録Frontiers in oncology2023
Ding Q, Li R, Wang Q, et al.
PGAM1 regulation of ASS1 contributes to the progression of breast cancer through the cAMP/AMPK/CEBPB pathway.学術論文その他の文献・記録ヒト有効な記録Molecular oncology2022
Liu M, Li R, Wang M, et al.
ASS1 regulates immune microenvironment via CXCL8 signaling in ovarian cancer.学術論文その他の文献・記録ヒト・動物 併記有効な記録Biochemical and biophysical research communications2022
Feng X, Ji Z, Yang G
Argininosuccinate synthase 1, arginine deprivation therapy and cancer management.学術論文レビュー未確定有効な記録Frontiers in pharmacology2022
Sun N, Zhao X
Therapeutic targeting of argininosuccinate synthase 1 (ASS1)-deficient pulmonary fibrosis.学術論文その他の文献・記録ヒト・動物 併記有効な記録Molecular therapy : the journal of the American Society of Gene Therapy2021
Li JM, Yang DC, Oldham J, et al.
Phase 1, pharmacogenomic, dose-expansion study of pegargiminase plus pemetrexed and cisplatin in patients with ASS1-deficient non-squamous non-small cell lung cancer.学術論文その他の文献・記録ヒト有効な記録Cancer medicine2021
Szlosarek PW, Wimalasingham AG, Phillips MM, et al.
Naturally-occurring spinosyn A and its derivatives function as argininosuccinate synthase activator and tumor inhibitor.学術論文その他の文献・記録ヒト・動物 併記有効な記録Nature communications2021
Zou Z, Hu X, Luo T, et al.
Argininosuccinate synthase 1 suppresses tumor progression through activation of PERK/eIF2α/ATF4/CHOP axis in hepatocellular carcinoma.学術論文その他の文献・記録ヒト・動物 併記有効な記録Journal of experimental & clinical cancer research : CR2021
Kim S, Lee M, Song Y, et al.
The prognostic and therapeutic implications of distinct patterns of argininosuccinate synthase 1 (ASS1) and arginase-2 (ARG2) expression by cancer cells and tumor stroma in non-small-cell lung cancer.学術論文その他の文献・記録未確定有効な記録Cancer & metabolism2021
Giatromanolaki A, Harris AL, Koukourakis MI
Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase-Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type.学術論文その他の文献・記録ヒト・動物 併記有効な記録Clinical cancer research : an official journal of the American Association for Cancer Research2020
Ji JX, Cochrane DR, Tessier-Cloutier B, et al.
Acid-Induced Downregulation of ASS1 Contributes to the Maintenance of Intracellular pH in Cancer.学術論文その他の文献・記録ヒト・動物 併記有効な記録Cancer research2019
Silberman A, Goldman O, Boukobza Assayag O, et al.
Argininosuccinate synthase 1 suppresses cancer cell invasion by inhibiting STAT3 pathway in hepatocellular carcinoma.学術論文その他の文献・記録ヒト・動物 併記有効な記録Acta biochimica et biophysica Sinica2019
Tao X, Zuo Q, Ruan H, et al.
Argininosuccinate Synthase 1 is a Metabolic Regulator of Colorectal Cancer Pathogenicity.学術論文その他の文献・記録ヒト有効な記録ACS chemical biology2017
Bateman LA, Ku WM, Heslin MJ, et al.
Argininosuccinate Synthase 1-Deficiency Enhances the Cell Sensitivity to Arginine through Decreased DEPTOR Expression in Endometrial Cancer.学術論文その他の文献・記録ヒト有効な記録Scientific reports2017
Ohshima K, Nojima S, Tahara S, et al.
Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p53.学術論文その他の文献・記録ヒト・動物 併記有効な記録Science advances2017
Miyamoto T, Lo PHY, Saichi N, et al.
Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells.学術論文その他の文献・記録ヒト・動物 併記有効な記録Science signaling2014
Qiu F, Chen YR, Liu X, et al.
ASS1 as a novel tumor suppressor gene in myxofibrosarcomas: aberrant loss via epigenetic DNA methylation confers aggressive phenotypes, negative prognostic impact, and therapeutic relevance.学術論文その他の文献・記録ヒト・動物 併記有効な記録Clinical cancer research : an official journal of the American Association for Cancer Research2013
Huang HY, Wu WR, Wang YH, et al.
Tumor necrosis factor-alpha reduces argininosuccinate synthase expression and nitric oxide production in aortic endothelial cells.学術論文その他の文献・記録動物有効な記録American journal of physiology. Heart and circulatory physiology2007
Goodwin BL, Pendleton LC, Levy MM, et al.
Induction of inducible nitric oxide synthase, argininosuccinate synthase, and GTP cyclohydrolase I in arthritic joints of human tumor necrosis factor-alpha transgenic mice.学術論文その他の文献・記録ヒト・動物 併記有効な記録The Journal of rheumatology2003
Hukkanen M, Platts LA, Haralambous S, et al.