Bibliographic records for ASS1 & Cancer. 36 records, version 2026-08-17.1, reference date 2026-08-17, 100 per page.
2 records lack a publication year. Patents and preprints are distinguished from scholarly articles using source publication types.
Additional records sharing normalized titles: 1. These are potential matches, not confirmed duplicate publications.
Spinosyn A derivatives as ASS1 activators and tumor inhibitors.Scholarly articleOther literature / recordsHumanActiveBioorganic & medicinal chemistry letters2026
Huang XY, Liu XH, Xu N, et al.
Arginine restriction exploits DNMT3B-ASS1-driven arginine auxotrophy and mTORC1-suppressed autophagy to overcome niraparib resistance in ovarian cancer.Scholarly articleOther literature / recordsHuman & animalActiveCancer letters2026
Wang H, Wang X, Zhang W, et al.
DDIT3, OTUB2, and ASS1 regulate arginine biosynthesis in colorectal cancer cells under arginine deficiency.Scholarly articleOther literature / recordsHuman & animalActiveCell reports2026
Li M, Zhang J, Zhang H, et al.
ASS1 Promotes Colorectal Cancer Immune Evasion Through CPT1A-Mediated S100A10 Succinylation.Scholarly articleOther literature / recordsHuman & animalActiveFrontiers in bioscience (Landmark edition)2026
Sun L, Fu D, Zhang H
ZFPL1 Promotes Colorectal Cancer Progression by Stabilizing ASS1 to Drive the Urea Cycle and M2 Macrophage-Mediated Metastatic Colonization.Scholarly articleOther literature / recordsHuman & animalActiveAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025
Qian X, Xie C, Zhang B, et al.
ASS1 enhances anoikis resistance via AMPK/CPT1A-mediated fatty acid metabolism in ovarian cancer.Scholarly articleOther literature / recordsHuman & animalActiveCancer letters2025
Feng X, Ji Z, Fan X, et al.
Advances in the impact of ASS1 dysregulation on metabolic reprogramming of tumor cells.Scholarly articleReviewHuman & animalActiveCellular signalling2025
Xia J, Liu W, Ni Y, et al.
ASS1 inhibits liver cancer by promoting CAD ubiquitination and reversing the urea cycle and pyrimidine synthesis imbalance.Scholarly articleOther literature / recordsHuman & animalActiveHepatology communications2025
Ming Z, Luo T, Zou Z, et al.
Etoposide-induced protein 2.4 homolog promotes argininosuccinate synthase 1 and cancer cell survival upon arginine deprivation.Scholarly articleOther literature / recordsHumanActiveCellular & molecular biology letters2025
Vo VTA, Tran LN, Bui TT, et al.
Sestrin3 confers resistance to recombinant human arginase in small cell lung cancer by activating Akt/mTOR/ASS1 axis.Scholarly articleOther literature / recordsHuman & animalActivePloS one2025
Zhang Z, Lin Z, Li W, et al.
Evodiamine Inhibits Colorectal Cancer by Downregulating ASS1 via Wnt/β-Catenin/c-MYC Pathway to Block Arginine Synthesis.Scholarly articleOther literature / recordsUnknownActivePharmaceuticals (Basel, Switzerland)2025
Wang H, Deng H, He J, et al.
LM2I leads to CAD ubiquitination and liver cancer suppression through activation of ASS1.Scholarly articleOther literature / recordsHuman & animalActiveActa biochimica et biophysica Sinica2025
Ming Z, Luo T, Zou Z, et al.
β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.Scholarly articleOther literature / recordsHumanActiveFree radical biology & medicine2024
Wang H, Liu J, Zhang Z, et al.
ASS1 inhibits triple-negative breast cancer by regulating PHGDH stability and de novo serine synthesis.Scholarly articleOther literature / recordsHuman & animalActiveCell death & disease2024
Luo W, Zou Z, Nie Y, et al.
ASS1-Mediated Reductive Carboxylation of Cytosolic Glutamine Confers Ferroptosis Resistance in Cancer Cells.Scholarly articleOther literature / recordsHumanActiveCancer research2023
Hu Q, Dai J, Zhang Z, et al.
A pan-cancer analysis of the role of argininosuccinate synthase 1 in human tumors.Scholarly articleOther literature / recordsUnknownActiveFrontiers in oncology2023
Ding Q, Li R, Wang Q, et al.
PGAM1 regulation of ASS1 contributes to the progression of breast cancer through the cAMP/AMPK/CEBPB pathway.Scholarly articleOther literature / recordsHumanActiveMolecular oncology2022
Liu M, Li R, Wang M, et al.
ASS1 regulates immune microenvironment via CXCL8 signaling in ovarian cancer.Scholarly articleOther literature / recordsHuman & animalActiveBiochemical and biophysical research communications2022
Feng X, Ji Z, Yang G
Argininosuccinate synthase 1, arginine deprivation therapy and cancer management.Scholarly articleReviewUnknownActiveFrontiers in pharmacology2022
Sun N, Zhao X
Therapeutic targeting of argininosuccinate synthase 1 (ASS1)-deficient pulmonary fibrosis.Scholarly articleOther literature / recordsHuman & animalActiveMolecular therapy : the journal of the American Society of Gene Therapy2021
Li JM, Yang DC, Oldham J, et al.
Phase 1, pharmacogenomic, dose-expansion study of pegargiminase plus pemetrexed and cisplatin in patients with ASS1-deficient non-squamous non-small cell lung cancer.Scholarly articleOther literature / recordsHumanActiveCancer medicine2021
Szlosarek PW, Wimalasingham AG, Phillips MM, et al.
Naturally-occurring spinosyn A and its derivatives function as argininosuccinate synthase activator and tumor inhibitor.Scholarly articleOther literature / recordsHuman & animalActiveNature communications2021
Zou Z, Hu X, Luo T, et al.
Argininosuccinate synthase 1 suppresses tumor progression through activation of PERK/eIF2α/ATF4/CHOP axis in hepatocellular carcinoma.Scholarly articleOther literature / recordsHuman & animalActiveJournal of experimental & clinical cancer research : CR2021
Kim S, Lee M, Song Y, et al.
The prognostic and therapeutic implications of distinct patterns of argininosuccinate synthase 1 (ASS1) and arginase-2 (ARG2) expression by cancer cells and tumor stroma in non-small-cell lung cancer.Scholarly articleOther literature / recordsUnknownActiveCancer & metabolism2021
Giatromanolaki A, Harris AL, Koukourakis MI
Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase-Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type.Scholarly articleOther literature / recordsHuman & animalActiveClinical cancer research : an official journal of the American Association for Cancer Research2020
Ji JX, Cochrane DR, Tessier-Cloutier B, et al.
Acid-Induced Downregulation of ASS1 Contributes to the Maintenance of Intracellular pH in Cancer.Scholarly articleOther literature / recordsHuman & animalActiveCancer research2019
Silberman A, Goldman O, Boukobza Assayag O, et al.
Argininosuccinate synthase 1 suppresses cancer cell invasion by inhibiting STAT3 pathway in hepatocellular carcinoma.Scholarly articleOther literature / recordsHuman & animalActiveActa biochimica et biophysica Sinica2019
Tao X, Zuo Q, Ruan H, et al.
Argininosuccinate Synthase 1 is a Metabolic Regulator of Colorectal Cancer Pathogenicity.Scholarly articleOther literature / recordsHumanActiveACS chemical biology2017
Bateman LA, Ku WM, Heslin MJ, et al.
Argininosuccinate Synthase 1-Deficiency Enhances the Cell Sensitivity to Arginine through Decreased DEPTOR Expression in Endometrial Cancer.Scholarly articleOther literature / recordsHumanActiveScientific reports2017
Ohshima K, Nojima S, Tahara S, et al.
Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p53.Scholarly articleOther literature / recordsHuman & animalActiveScience advances2017
Miyamoto T, Lo PHY, Saichi N, et al.
Arginine starvation impairs mitochondrial respiratory function in ASS1-deficient breast cancer cells.Scholarly articleOther literature / recordsHuman & animalActiveScience signaling2014
Qiu F, Chen YR, Liu X, et al.
ASS1 as a novel tumor suppressor gene in myxofibrosarcomas: aberrant loss via epigenetic DNA methylation confers aggressive phenotypes, negative prognostic impact, and therapeutic relevance.Scholarly articleOther literature / recordsHuman & animalActiveClinical cancer research : an official journal of the American Association for Cancer Research2013
Huang HY, Wu WR, Wang YH, et al.
Tumor necrosis factor-alpha reduces argininosuccinate synthase expression and nitric oxide production in aortic endothelial cells.Scholarly articleOther literature / recordsAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2007
Goodwin BL, Pendleton LC, Levy MM, et al.
Induction of inducible nitric oxide synthase, argininosuccinate synthase, and GTP cyclohydrolase I in arthritic joints of human tumor necrosis factor-alpha transgenic mice.Scholarly articleOther literature / recordsHuman & animalActiveThe Journal of rheumatology2003
Hukkanen M, Platts LA, Haralambous S, et al.
Arginine depletion through ADI-PEG20 to treat argininosuccinate synthase deficient ovarian cancer, including small cell carcinoma of the ovary, hypercalcemic typePreprintDesign not determinedUnknownUnknownYear not recorded
Ji JX, Cochrane DR, Tessier-Cloutier B, et al.
Argininosuccinate Synthase 1 Suppresses Tumor Progression Through Activation of PERK/eIF2α/ATF4/CHOP Axis in Hepatocellular CarcinomaPreprintDesign not determinedUnknownUnknownYear not recorded
Kim S, Lee M, Song Y, et al.