Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond.ReviewHuman & animalActiveAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026
Andrabi SM, Sharma NS, Rather IG, et al.
Chemical profile and anti-inflammatory activity of the hydroethanolic extract of Cochlospermum regium (Schrank) Pilg. xylopodium.Other primary literatureAnimalActiveInflammopharmacology2026
Muller JAI, Di Serio BF, Figueiredo FF, et al.
Nitric oxide-releasing dextran surface with enhanced albumin affinity mitigates infection and foreign body reaction.Other primary literatureAnimalActiveCarbohydrate polymers2026
Wu Y, Sapkota A, Wilson SN, et al.
Nicorandil ameliorates neuropathic and inflammatory pain via TNF-α, IL6/MAPK<sub>ERK1/2</sub> and NO/cGMP signaling.Other primary literatureAnimalActiveScientific reports2026
Badr RM, Abuiessa SA, Elblehi SS, et al.
Graveoumarins A-C: chiral resolution, absolute configuration, and anticoagulant/anti-inflammatory activities of 3'-methyl-3'-butenyl coumarins from <i>ruta graveolens</i> L.Other primary literatureAnimalActivePharmaceutical biology2026
Wu Z, Liao X, Wang Y, et al.
Structure and dynamics of a multidomain nitric oxide synthase regulated by a C2 domain.Other primary literatureUnknownActiveScience advances2026
Nair D, Crane BR
Phytochemical and Geographical Comparison of <i>Derris scandens</i> (Roxb.) Benth. Leaves and Stems and Their Nitric Oxide Production Inhibitory Activity.Other primary literatureUnknownActiveScientifica2026
Buajan B, Nisoa M, Makkliang F, et al.
Geraniin Mitigates Neuropathic Pain Through Antioxidant, Anti-Inflammatory, and Nitric Oxide Modulation in a Rat Model of Chronic Constriction Injury.Other primary literatureAnimalActiveInternational journal of molecular sciences2026
Yang CC, Wang MH, Lin YW, et al.
Plant-derived phenolics as regulators of nitric oxide production in microglia: mechanisms and therapeutic potential.ReviewHuman & animalActiveMedical gas research2026
Sahakyan N
NO-Driven Janus Nanomotor Enhances T-Cell Infiltration by Reconstructing Tumor-Associated Blood and Lymphatic Vessels.Other primary literatureAnimalActiveAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025
Ma Q, Fu S, Xia Y, et al.
The Distribution of Nitric Oxide-Synthesizing Neurons and Soluble Guanylate Cyclase in Relation to Dopaminergic Systems in the Pigeon Brain.Other primary literatureAnimalActiveThe Journal of comparative neurology2025
Steinemer A, Ziegler M, Haselhuhn K, et al.
Astrocytic Inducible Nitric Oxide Synthase Upregulation Contributes to Chronic Below-Level Neuropathic Pain Following Spinal Cord Injury in Male Rats.Other primary literatureAnimalActiveEuropean journal of pain (London, England)2025
Kim Y, Kang H, Yoon YW
Psilocin, A Psychedelic Drug, Exerts Anticonvulsant Effects Against PTZ- and MES-Induced Seizures in Mice via 5-HT1A and CB1 Receptors: Involvement of Nitrergic, Opioidergic, and Kynurenine Pathways.Other primary literatureAnimalActivePharmacology research & perspectives2025
Balabandian M, Manavi MA, Lesani A, et al.
Oxidative stress biomarkers in fetal growth restriction: a systematic review and meta-analysis.Meta-analysisHumanActiveArchives of gynecology and obstetrics2025
Li L, Zhou L, Li W, et al.
The molecular mechanism of nitric oxide in memory consolidation and its role in the pathogenesis of memory-related disorders.ReviewHuman & animalActiveNeurogenetics2025
Bahdar ZI, Abu-El-Rub E, Almazari R, et al.
Nitric oxide releasing graphene for next-generation therapeutics.ReviewHuman & animalActiveAdvanced drug delivery reviews2025
Tabish TA, Lygate CA
Self-Assembled Peptide-Based Fibrous Hydrogel as a Biological Catalytic Scaffold for Nitric Oxide Generation and Encapsulation.Other primary literatureAnimalActiveACS applied materials & interfaces2025
Younis M, Tabish TA, Firdharini C, et al.
S-nitrosylation of EZH2 alters PRC2 assembly, methyltransferase activity, and EZH2 stability to maintain endothelial homeostasis.Other primary literatureHuman & animalActiveNature communications2025
Sakhuja A, Bhattacharyya R, Katakia YT, et al.
Decreased non-neurogenic acetylcholine in bone marrow triggers age-related defective stem/progenitor cell homing.Other primary literatureHuman & animalActiveNature communications2025
Morikawa T, Fujita S, Sugiura Y, et al.
Biologically active withanolides from <i>Physalis peruviana</i>.Other primary literatureAnimalActivePharmaceutical biology2025
Sang-Ngern M, Fukuchi A, Kondratyuk TP, et al.
Bioactive constituents from the edible seaweed <i>Halymenia hawaiiana</i> (Rhodophyta).Other primary literatureHuman & animalActivePharmaceutical biology2025
Raksat A, Atanu MSH, McDermid KJ, et al.
Sickle Trait and Alpha Thalassemia Increase NOS-Dependent Vasodilation of Human Arteries Through Disruption of Endothelial Hemoglobin-eNOS Interactions.Other primary literatureHumanActiveCirculation2025
Brooks SD, Ruhl AP, Zeng X, et al.
Phytol nanoemulsions encapsulated alginate hydrogel beads for the protection and management of alcohol-induced gastric ulcer via nitric oxide synthase and NF-κB/IL-6/TGF-β modulation.Other primary literatureAnimalActivePloS one2025
Ragab TIM, Kassem AM, Abdallah HMI, et al.
Phytochemical Analysis, Computational Study, and in vitro Assay of <i>Etlingera elatior</i> Inflorescence Extract Towards Inducible Nitric Oxide Synthase.Other primary literatureUnknownActiveJournal of experimental pharmacology2025
Prayoga DK, Pitaloka DAE, Aulifa DL, et al.
Nitric oxide regulates photosynthesis and the capacity of the antioxidant system under water deficit and rehydration in <i>Lolium multiflorum</i>/<i>Festuca arundinacea</i> introgression forms.Other primary literatureUnknownActiveFrontiers in plant science2025
Perlikowski D, Lechowicz K, Blicharz S, et al.
A Theoretical Analysis of the Effects That the Glycocalyx and the Internal Elastic Lamina Have on Nitric Oxide Concentration Gradients in the Arterial Wall.Other primary literatureUnknownActiveAntioxidants (Basel, Switzerland)2025
Nartsissov YR, Seraya IP
Functional and Genomic Evidence of L-Arginine-Dependent Bacterial Nitric Oxide Synthase Activity in <i>Paenibacillus nitricinens</i> sp. nov.Other primary literatureUnknownActiveBiology2025
Saavedra-Tralma D, Gaete A, Merino-Guzmán C, et al.
<i>iNOS</i> Mediates High-Fat Diet-Associated Aggravation of Complete Freund's Adjuvant-Induced Inflammatory Pain.Other primary literatureAnimalActiveInternational journal of molecular sciences2025
Lee EW, Wang L, Liu JA, et al.
Unlocking Implantation: The Role of Nitric Oxide, NO<sub>2</sub>-NO<sub>3</sub>, and eNOS in Endometrial Receptivity and IVF Success-A Systematic Review.Systematic reviewHuman & animalActiveInternational journal of molecular sciences2025
Voros C, Sapantzoglou I, Mavrogianni D, et al.
Dolabellane Diterpenoids from Soft Coral <i>Clavularia viridis</i> with Anti-Inflammatory Activities.Other primary literatureAnimalActiveMarine drugs2025
Gu C, Jia H, Zhou K, et al.
Design, Synthesis, Biological Evaluation, and In Silico Studies of Novel Multitarget Cinnamic Acid Hybrids.Other primary literatureHumanActiveMolecules (Basel, Switzerland)2025
Tsopka IC, Pontiki E, Sigala I, et al.
L-Arginine and Nitric Oxide in Vascular Regulation-Experimental Findings in the Context of Blood Donation.ReviewHuman & animalActiveNutrients2025
Kurhaluk N, Tkaczenko H
Exogenous Nitric Oxide Promotes the Growth and Cadmium Accumulation of Alfalfa (<i>Medicago sativa</i>) Seedlings Under Cadmium Stress.Other primary literatureUnknownActivePlants (Basel, Switzerland)2025
Chen Y, Sun Y, Cao B, et al.
The emerging role of nitric oxide in the synaptic dysfunction of vascular dementia.Other primary literatureUnknownActiveNeural regeneration research2025
Zhang X, Chen Z, Xiong Y, et al.
Effect of Micronized Purified Flavonoid Fraction Containing Hesperidin and Diosmin on Vincristine-Induced Neuropathy in Rats; the Role of Nitric Oxide Pathway.Other primary literatureUnknownActiveIranian journal of pharmaceutical research : IJPR2025
Abharian N, Naderi N, Nikray N, et al.
Hydrogels for Gasotransmitter Delivery: Nitric Oxide, Carbon Monoxide, and Hydrogen Sulfide.ReviewUnknownActiveMacromolecular bioscience2024
Sarkar S, Kumar R, Matson JB
Heat stress-induced NO enhanced perylenequinone biosynthesis of Shiraia sp. via calcium signaling pathway.Other primary literatureUnknownActiveApplied microbiology and biotechnology2024
Bao Z, Chen Y, Zhang Z, et al.
Nitric Oxide Releasing Nanomaterials for Cardiovascular Applications.ReviewUnknownActiveJACC. Basic to translational science2024
Tabish TA, Crabtree MJ, Townley HE, et al.
Immunomodulatory Effects and Regulatory Mechanisms of (R)-6-HITC, an Isothiocyanate from Wasabi (Eutrema japonicum), in an Ex Vivo Mouse Model of LPS-Induced Inflammation.Other primary literatureHuman & animalActiveJournal of agricultural and food chemistry2024
Alcarranza M, Alarcón-de-la-Lastra C, Recio Jiménez R, et al.
Enhanced breast cancer therapy using multifunctional lipid-coated nanoparticles combining curcumin chemotherapy and nitric oxide gas delivery.Other primary literatureHuman & animalActiveScientific reports2024
Yan Z, Xiao P, Ji P, et al.
Synthesis and characterization of amine-functionalized graphene as a nitric oxide-generating coating for vascular stents.Other primary literatureUnknownActiveApplied physics reviews2024
Tabish TA, Hussain MZ, Zhu Y, et al.
Endothelial histone deacetylase 1 activity impairs kidney microvascular NO signaling in rats fed a high-salt diet.Other primary literatureAnimalActiveActa physiologica (Oxford, England)2024
Dunaway LS, Cook AK, Kellum CE, et al.
Psoralen Isolated from the Roots of Dorstenia psilurus Welw. Modulate Th1/Th2 Cytokines and Inflammatory Enzymes in LPS-Stimulated RAW 264.7 Macrophages.Other primary literatureAnimalActiveMediators of inflammation2024
Isa AI, Fouotsa H, Mohammed OA, et al.
mir-605-3p prevents liver premetastatic niche formation by inhibiting angiogenesis via decreasing exosomal nos3 release in gastric cancer.Other primary literatureUnknownActiveCancer cell international2024
Hu Y, Zang W, Feng Y, et al.
Closer look at circulating nitric oxide levels and their association with polycystic ovary syndrome: A meta-analytical exploration.Other primary literatureUnknownActiveInternational journal of reproductive biomedicine2024
Bahreiny SS, Ahangarpour A, Harooni E, et al.
Effect of Acute Administration of Caffeine on Neuropathic Pain and the Role of Nitric Oxide Pathway in an Animal Model of Chronic Constriction Injury.Other primary literatureUnknownActiveBasic and clinical neuroscience2024
Naderi Tehrani M, Hamidi GA, Heydari A, et al.
Breath and Sputum Analyses in Asthmatic Patients: An Overview.ReviewHumanActiveCells2024
Soccio P, Quarato CMI, Tondo P, et al.
The Inhibition Activity of Natural Methoxyflavonoid from Inula britannica on Soluble Epoxide Hydrolase and NO Production in RAW264.7 Cells.Other primary literatureAnimalActiveInternational journal of molecular sciences2024
Kim JH, Han KS, Lee ES, et al.
Mechanisms of Flavonoids and Their Derivatives in Endothelial Dysfunction Induced by Oxidative Stress in Diabetes.ReviewHuman & animalActiveMolecules (Basel, Switzerland)2024
Dou B, Zhu Y, Sun M, et al.
The effects of nitric oxide in Alzheimer's disease.ReviewHuman & animalActiveMedical gas research2024
Wang L, Lu D, Wang X, et al.
Deleterious Effects of Caffeine Consumption on Reproductive Functions of Female Wistar Rats.Other primary literatureAnimalActiveJBRA assisted reproduction2024
Ogunwole E, Emojevwe VO, Shittu HB, et al.
Flavonoids as a therapeutical option for the treatment of thrombotic complications associated with COVID-19.ReviewHumanActivePhytotherapy research : PTR2023
Quintal Martínez JP, Segura Campos MR
Title: β3 Adrenergic Receptor Signaling in the Human Myometrium.Other primary literatureHumanActiveReproductive sciences (Thousand Oaks, Calif.)2023
Asif H, Barnett SD, Buxton ILO
Astrocytes produce nitric oxide via nitrite reduction in mitochondria to regulate cerebral blood flow during brain hypoxia.Other primary literatureHumanActiveCell reports2023
Christie IN, Theparambil SM, Braga A, et al.
Anti-inflammatory Activity of Tanshinone-Related Diterpenes from Perovskia artemisioides Roots.Other primary literatureUnknownActiveJournal of natural products2023
Sadeghi Z, Cerulli A, Marzocco S, et al.
A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase.Other primary literatureAnimalActiveNature communications2023
Ragavan VN, Nair PC, Jarzebska N, et al.
Enhanced pericyte-endothelial interactions through NO-boosted extracellular vesicles drive revascularization in a mouse model of ischemic injury.Other primary literatureHuman & animalActiveNature communications2023
Guo L, Yang Q, Wei R, et al.
Effects of endothelial nitric oxide synthase on mouse arteriovenous fistula hemodynamics.Other primary literatureAnimalActiveScientific reports2023
Baltazar S, Northrup H, Chang J, et al.
Inhaled Nitric Oxide in Acute Respiratory Distress Syndrome Subsets: Rationale and Clinical Applications.ReviewHumanActiveJournal of aerosol medicine and pulmonary drug delivery2023
Redaelli S, Pozzi M, Giani M, et al.
Investigating multi-material hydrogel three-dimensional printing for in vitro representation of the neo-vasculature of solid tumours: a comprehensive mechanical analysis and assessment of nitric oxide release from human umbilical vein endothelial cells.Other primary literatureUnknownActiveRoyal Society open science2023
Asciak L, Gilmour L, Williams JA, et al.
Nitric oxide synthase and reduced arterial tone contribute to arteriovenous malformation.Other primary literatureAnimalActiveScience advances2023
Huang L, Cheng F, Zhang X, et al.
Repurposing nitric oxide donating drugs in cancer therapy through immune modulation.Other primary literatureAnimalActiveJournal of experimental & clinical cancer research : CR2023
Li CY, Anuraga G, Chang CP, et al.
Peroxynitrite Contributes to Behavioral Responses, Increased Trigeminal Excitability, and Changes in Mitochondrial Function in a Preclinical Model of Migraine.Other primary literatureHuman & animalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2023
Lackovic J, Jeevakumar V, Burton M, et al.
Salivary Nitric Oxide Levels in Adults with Different DMFT Scores in a Selected Iranian Population: A Cross-Sectional Study.Other primary literatureUnknownActiveActa stomatologica Croatica2023
Esfehani M, Keshavarzi Z, Mirzadeh M, et al.
Yangjing capsule improves oligoasthenozoospermia by promoting nitric oxide production through PLCγ1/AKT/eNOS pathway.Other primary literatureUnknownActiveFrontiers in pharmacology2023
Deng W, Sun D, Cai B, et al.
Effects of L-arginine on Nitric Oxide Synthesis and Larval Metamorphosis of Mytilus coruscus.Other primary literatureAnimalActiveGenes2023
Zhu YT, Liang LL, Liu TT, et al.
Effects of Nitric Oxide on the Activity of P2X and TRPV1 Receptors in Rat Meningeal Afferents of the Trigeminal Nerve.Other primary literatureAnimalActiveInternational journal of molecular sciences2023
Koroleva K, Svitko S, Ananev A, et al.
New Triterpenoids and Anti-Inflammatory Constituents from Glinus oppositifolius.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2023
Chen JJ, Yang CS, Chen YH, et al.
Vasorelaxant Activity of Salvia hispanica L.: Involvement of the Nitric Oxide Pathway in Its Pharmacological Mechanism.Other primary literatureUnknownActiveMolecules (Basel, Switzerland)2023
Herbert-Doctor LA, Sánchez-Recillas A, Ortiz-Andrade R, et al.
The Mechanism of Biochemical NO-Sensing: Insights from Computational Chemistry.Other primary literatureHumanActiveChemistry (Weinheim an der Bergstrasse, Germany)2022
Rozza AM, Papp M, McFarlane NR, et al.
Evaluation of salivary and serum methylated arginine metabolites and nitric oxide synthase in advanced periodontitis patients.Other primary literatureHumanActiveClinical oral investigations2022
Şengül V, Güney Z, Kurgan Ş, et al.
Design, synthesis and evaluation of 15N- and 13C-labeled molecular probes as hyperpolarized nitric oxide sensors.Other primary literatureUnknownActiveBioorganic & medicinal chemistry2022
Park H, Eriksson S, Warren WS, et al.
Nitric oxide: Clinical applications in critically ill patients.ReviewHumanActiveNitric oxide : biology and chemistry2022
Redaelli S, Magliocca A, Malhotra R, et al.
Structural snapshots of nitrosoglutathione binding and reactivity underlying S-nitrosylation of photosynthetic GAPDH.Other primary literatureUnknownActiveRedox biology2022
Mattioli EJ, Rossi J, Meloni M, et al.
High-throughput production of functional prototissues capable of producing NO for vasodilation.Other primary literatureAnimalActiveNature communications2022
Zhang X, Li C, Liu F, et al.
Novel indolic AMPK modulators induce vasodilatation through activation of the AMPK-eNOS-NO pathway.Other primary literatureHuman & animalActiveScientific reports2022
Sanz-Gómez M, Aledavood E, Beroiz-Salaverri M, et al.
Scavenging of nitric oxide up-regulates photosynthesis under drought in Festuca arundinacea and F. glaucescens but reduces their drought tolerance.Other primary literatureUnknownActiveScientific reports2022
Perlikowski D, Lechowicz K, Pawłowicz I, et al.
TEB/POLQ plays dual roles in protecting Arabidopsis from NO-induced DNA damage.Other primary literatureUnknownActiveNucleic acids research2022
Lv Q, Han S, Wang L, et al.
Understanding the Cellular Sources of the Fractional Exhaled Nitric Oxide (FeNO) and Its Role as a Biomarker of Type 2 Inflammation in Asthma.ReviewHumanActiveBioMed research international2022
Escamilla-Gil JM, Fernandez-Nieto M, Acevedo N
Endothelial cell-specific loss of eNOS differentially affects endothelial function.Other primary literatureUnknownActivePloS one2022
Bu S, Nguyen HC, Nikfarjam S, et al.
Effects of arginase inhibition on myocardial Ca2+ and contractile responses.Other primary literatureAnimalActivePhysiological reports2022
Cho JS, Han YS, Jensen C, et al.
The Role of Nitric Oxide on Male and Female Reproduction.ReviewUnknownActiveThe Malaysian journal of medical sciences : MJMS2022
Dutta S, Sengupta P
Medial prefrontal cortex nitric oxide modulates neuropathic pain behavior through mu opioid receptors in rats.Other primary literatureUnknownActiveThe Korean journal of pain2022
Raisian D, Erfanparast A, Tamaddonfard E, et al.
Xiongshao Zhitong Recipe Attenuates Nitroglycerin-Induced Migraine-Like Behaviors via the Inhibition of Inflammation Mediated by Nitric Oxide Synthase.Other primary literatureUnknownCorrectedFrontiers in pharmacology2022
Yang S, Chen C, Liu X, et al.
The Antioxidant N-Acetyl-L-Cysteine Restores the Behavioral Deficits in a Neurodevelopmental Model of Schizophrenia Through a Mechanism That Involves Nitric Oxide.Other primary literatureUnknownActiveFrontiers in pharmacology2022
Lopes-Rocha A, Bezerra TO, Zanotto R, et al.
Effect of Nitric Oxide Pathway Inhibition on the Evolution of Anaphylactic Shock in Animal Models: A Systematic Review.ReviewUnknownActiveBiology2022
Alfalasi M, Alzaabi S, Östlundh L, et al.
Design, Synthesis, and Antisickling Investigation of a Nitric Oxide-Releasing Prodrug of 5HMF for the Treatment of Sickle Cell Disease.Other primary literatureHumanActiveBiomolecules2022
Alhashimi RT, Ghatge MS, Donkor AK, et al.
Impairment of Anti-Aggregatory Responses to Nitric Oxide and Prostacyclin: Mechanisms and Clinical Implications in Cardiovascular Disease.ReviewHumanActiveInternational journal of molecular sciences2022
Chirkov YY, Nguyen TH, Horowitz JD
Effects of iNOS in Hepatic Warm Ischaemia and Reperfusion Models in Mice and Rats: A Systematic Review and Meta-Analysis.Meta-analysisHuman & animalActiveInternational journal of molecular sciences2022
Nakatake R, Schulz M, Kalvelage C, et al.
Anthraquinones from the Aerial Parts of Rubia cordifolia with Their NO Inhibitory and Antibacterial Activities.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2022
Luo H, Qin W, Zhang H, et al.
Anti-Neuroinflammatory Components from Clausena lenis Drake.Other primary literatureUnknownActiveMolecules (Basel, Switzerland)2022
Zhu SS, Zhang YF, Ding M, et al.
Identification of Potential Anti-Neuroinflammatory Inhibitors from Antarctic Fungal Strain Aspergillus sp. SF-7402 via Regulating the NF-κB Signaling Pathway in Microglia.Other primary literatureUnknownActiveMolecules (Basel, Switzerland)2022
Cao TQ, Liu Z, Dong L, et al.
Anti-Inflammatory Activity of Oxyresveratrol Tetraacetate, an Ester Prodrug of Oxyresveratrol, on Lipopolysaccharide-Stimulated RAW264.7 Macrophage Cells.Other primary literatureHuman & animalActiveMolecules (Basel, Switzerland)2022
Thaweesest W, Buranasudja V, Phumsuay R, et al.
Wild Watermelon-Extracted Juice Ingestion Reduces Peripheral Arterial Stiffness with an Increase in Nitric Oxide Production: A Randomized Crossover Pilot Study.Randomized controlled trialHumanActiveNutrients2022
Fujie S, Iemitsu K, Inoue K, et al.
Tryptophan Levels as a Marker of Auxins and Nitric Oxide Signaling.Other primary literatureUnknownActivePlants (Basel, Switzerland)2022
López-Gómez P, Smith EN, Bota P, et al.
An auto-inhibited state of protein kinase G and implications for selective activation.Other primary literatureAnimalActiveeLife2022
Sharma R, Kim JJ, Qin L, et al.
Nitric Oxide in the Management of Respiratory Consequences in COVID-19: A Scoping Review of a Different Treatment Approach.Other primary literatureUnknownActiveCureus2022
Ghosh A, Joseph B, Anil S
Maintenance of the Neuroprotective Function of the Amino Group Blocked Fluorescence-Agmatine.Other primary literatureAnimalActiveNeurochemical research2021
Barua S, Sim AY, Kim JY, et al.
Computational modeling of nasal nitric oxide flux from the paranasal sinuses: Validation against human experiment.Other primary literatureHumanActiveComputers in biology and medicine2021
Spector BM, Shusterman DJ, Goldberg AN, et al.
Melatonin interferes with COVID-19 at several distinct ROS-related steps.ReviewHumanActiveJournal of inorganic biochemistry2021
Camp OG, Bai D, Gonullu DC, et al.
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents.Other primary literatureHumanCorrectedJournal of medicinal chemistry2021
Fallica AN, Barbaraci C, Amata E, et al.
Inhalational Gases for Neuroprotection in Traumatic Brain Injury.Systematic reviewHuman & animalActiveJournal of neurotrauma2021
Shin SS, Hwang M, Diaz-Arrastia R, et al.
Effect of food sources of nitrate, polyphenols, L-arginine and L-citrulline on endurance exercise performance: a systematic review and meta-analysis of randomised controlled trials.Meta-analysisHumanActiveJournal of the International Society of Sports Nutrition2021
d'Unienville NMA, Blake HT, Coates AM, et al.
Association of endothelial nitric oxide synthase gene variants with preeclampsia.Meta-analysisHumanActiveReproductive health2021
Shaheen G, Jahan S, Bibi N, et al.
New bakuchiol dimers from Psoraleae Fructus and their inhibitory activities on nitric oxide production.Other primary literatureUnknownActiveChinese medicine2021
Xu Q, Lv Q, Liu L, et al.
Type I Interferons Are Involved in the Intracellular Growth Control of Mycobacterium abscessus by Mediating NOD2-Induced Production of Nitric Oxide in Macrophages.Other primary literatureAnimalActiveFrontiers in immunology2021
Ahn JH, Park JY, Kim DY, et al.
Crambescin C1 Acts as A Possible Substrate of iNOS and eNOS Increasing Nitric Oxide Production and Inducing In Vivo Hypotensive Effect.Other primary literatureUnknownActiveFrontiers in pharmacology2021
Rubiolo JA, Lence E, González-Bello C, et al.
Nitric Oxide Enhances Photosynthetic Nitrogen and Sulfur-Use Efficiency and Activity of Ascorbate-Glutathione Cycle to Reduce High Temperature Stress-Induced Oxidative Stress in Rice (Oryza sativa L.) Plants.Other primary literatureUnknownActiveBiomolecules2021
Gautam H, Sehar Z, Rehman MT, et al.
Microglia-Derived Small Extracellular Vesicles Reduce Glioma Growth by Modifying Tumor Cell Metabolism and Enhancing Glutamate Clearance through miR-124.Other primary literatureAnimalActiveCells2021
Serpe C, Monaco L, Relucenti M, et al.
Bioactive Phytochemicals from Mulberry: Potential Anti-Inflammatory Effects in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages.Other primary literatureAnimalActiveInternational journal of molecular sciences2021
Lee D, Lee SR, Kang KS, et al.
Effects of Sodium-Glucose Co-Transporter 2 Inhibitors on Vascular Cell Function and Arterial Remodeling.ReviewHumanActiveInternational journal of molecular sciences2021
Durante W, Behnammanesh G, Peyton KJ
The Involvement of l-Arginine-Nitric Oxide-cGMP-ATP-Sensitive K+ Channel Pathway in Antinociception of BBHC, a Novel Diarylpentanoid Analogue, in Mice Model.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2021
Ong HM, Ahmad Azmi AF, Leong SW, et al.
Mechanisms of Dietary Sodium-Induced Impairments in Endothelial Function and Potential Countermeasures.ReviewHuman & animalActiveNutrients2021
Patik JC, Lennon SL, Farquhar WB, et al.
Aqueous extract of Dendrobium officinale confers neuroprotection against hypoxic-ischemic brain damage in neonatal rats.Other primary literatureAnimalActiveThe Kaohsiung journal of medical sciences2020
Li XL, Hong M
Synthesis and Antitumor Evaluation of Novel Hybrids of Phenylsulfonylfuroxan and Estradiol Derivatives.Other primary literatureHumanActiveChemistryOpen2020
Wan Q, Deng Y, Huang Y, et al.
Immunomodulatory and antiparasitic effects of garlic-arteether combination via nitric oxide pathway in Plasmodium berghei-infected mice.Other primary literatureUnknownActiveJournal of parasitic diseases : official organ of the Indian Society for Parasitology2020
Vathsala PG, Krishna Murthy P
Improving effect of combined inorganic nitrate and nitric oxide synthase inhibitor on pancreatic oxidative stress and impaired insulin secretion in streptozotocin induced-diabetic rats.Other primary literatureUnknownActiveJournal of diabetes and metabolic disorders2020
Shahraki ZS, Karbalaei N, Nemati M
A Review on Microvascular Hemodynamics: The Control of Blood Flow Distribution and Tissue Oxygenation.ReviewHumanActiveCritical care clinics2020
Munoz CJ, Lucas A, Williams AT, et al.
Involvement of nitric oxide pathway in the anti-inflammatory effect of modafinil on indomethacin-, stress-, and ethanol -induced gastric mucosal injury in rat.Other primary literatureAnimalActiveEuropean journal of pharmacology2020
Dejban P, Eslami F, Rahimi N, et al.
Disrupted endothelial cell heterogeneity and network organization impair vascular function in prediabetic obesity.Other primary literatureAnimalActiveMetabolism: clinical and experimental2020
Wilson C, Zhang X, Lee MD, et al.
A flexible and physically transient electrochemical sensor for real-time wireless nitric oxide monitoring.Other primary literatureAnimalActiveNature communications2020
Li R, Qi H, Ma Y, et al.
Acute 4,4'-Methylene Diphenyl Diisocyanate Exposure-Mediated Downregulation of miR-206-3p and miR-381-3p Activates Inducible Nitric Oxide Synthase Transcription by Targeting Calcineurin/NFAT Signaling in Macrophages.Other primary literatureAnimalActiveToxicological sciences : an official journal of the Society of Toxicology2020
Lin CC, Law BF, Hettick JM
Tyrosine Nitration Contributes to Nitric Oxide-Stimulated Degradation of CYP2B6.Other primary literatureHumanActiveMolecular pharmacology2020
Lee CM, Wilderman PR, Park JW, et al.
Tyrosine Nitration of Flagellins: a Response of Sinorhizobium meliloti to Nitrosative Stress.Other primary literatureUnknownActiveApplied and environmental microbiology2020
Cazalé AC, Blanquet P, Henry C, et al.
Nitric Oxide Stimulates Acute Pancreatitis Pain via Activating the NF-κB Signaling Pathway and Inhibiting the Kappa Opioid Receptor.Other primary literatureAnimalActiveOxidative medicine and cellular longevity2020
Xue M, Han L, Qian W, et al.
Partial loss of endothelial nitric oxide leads to increased cerebrovascular beta amyloid.Other primary literatureAnimalActiveJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2020
Austin SA, Katusic ZS
Inducible nitric oxide synthase and systemic lupus erythematosus: a systematic review and meta-analysis.Meta-analysisHuman & animalActiveBMC immunology2020
Pan L, Yang S, Wang J, et al.
Nanomaterial Nitric Oxide Delivery in Traumatic Orthopedic Regenerative Medicine.ReviewUnknownActiveFrontiers in bioengineering and biotechnology2020
Anastasio AT, Paniagua A, Diamond C, et al.
Anti-Inflammatory Effects of the Novel PIM Kinase Inhibitor KMU-470 in RAW 264.7 Cells through the TLR4-NF-κB-NLRP3 Pathway.Other primary literatureAnimalActiveInternational journal of molecular sciences2020
Baek HS, Min HJ, Hong VS, et al.
Aspidoptoids A-D: Four New Diterpenoids from Aspidopterys obcordata Vine.Other primary literatureHuman & animalActiveMolecules (Basel, Switzerland)2020
Sun P, Cao DH, Xiao YD, et al.
Anti-Inflammatory Principles from Tamarix aphylla L.: A Bioassay-Guided Fractionation Study.Other primary literatureHumanActiveMolecules (Basel, Switzerland)2020
Gadallah AS, Mujeeb-Ur-Rehman, Atta-Ur-Rahman, et al.
Retrofractamide C Derived from Piper longum Alleviates Xylene-Induced Mouse Ear Edema and Inhibits Phosphorylation of ERK and NF-κB in LPS-Induced J774A.1.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2020
Lim HJ, Bak SG, Park EJ, et al.
Benzophenone and Benzoylphloroglucinol Derivatives from Hypericum sampsonii with Anti-Inflammatory Mechanism of Otogirinin A.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2020
Huang CY, Chang TC, Wu YJ, et al.
Secoiridoid Glucosides and Anti-Inflammatory Constituents from the Stem Bark of Fraxinus chinensis.Other primary literatureHuman & animalActiveMolecules (Basel, Switzerland)2020
Chang HC, Wang SW, Chen CY, et al.
New Cyclic Diarylheptanoids from Platycarya strobilacea.Other primary literatureHuman & animalActiveMolecules (Basel, Switzerland)2020
Ding WB, Zhao RY, Li GH, et al.
Effects of Arginine Supplementation on Athletic Performance Based on Energy Metabolism: A Systematic Review and Meta-Analysis.Meta-analysisHumanActiveNutrients2020
Viribay A, Burgos J, Fernández-Landa J, et al.
Cardiomyocyte-derived small extracellular vesicles can signal eNOS activation in cardiac microvascular endothelial cells to protect against Ischemia/Reperfusion injury.Other primary literatureHuman & animalActiveTheranostics2020
Chen G, Xu C, Gillette TG, et al.
Extracellular Alpha-Synuclein Oligomers Induce Parkin S-Nitrosylation: Relevance to Sporadic Parkinson's Disease Etiopathology.Other primary literatureHuman & animalActiveMolecular neurobiology2019
Wilkaniec A, Lenkiewicz AM, Czapski GA, et al.
Aqueous and methanol extracts of Paullinia pinnata L. (Sapindaceae) improve inflammation, pain and histological features in CFA-induced mono-arthritis: Evidence from in vivo and in vitro studies.Other primary literatureHuman & animalActiveJournal of ethnopharmacology2019
Tseuguem PP, Ngangoum DAM, Pouadjeu JM, et al.
Drug-Mimicking Nanofibrous Peptide Hydrogel for Inhibition of Inducible Nitric Oxide Synthase.Other primary literatureUnknownActiveACS biomaterials science & engineering2019
Leach DG, Newton JM, Florez MA, et al.
First trimester placental endothelial cells from pregnancies with abnormal uterine artery Doppler are more sensitive to apoptotic stimuli.Other primary literatureHumanActiveLaboratory investigation; a journal of technical methods and pathology2019
Charolidi N, Host AJ, Ashton S, et al.
The effect of endothelial nitric oxide synthase on the hemodynamics and wall mechanics in murine arteriovenous fistulas.Other primary literatureAnimalCorrectedScientific reports2019
Pike D, Shiu YT, Cho YF, et al.
Promotion of angiogenesis by M13 phage and RGD peptide in vitro and in vivo.Other primary literatureHumanActiveScientific reports2019
Safari Z, Soudi S, Jafarzadeh N, et al.
TLR-2 mediated cytosolic-Ca2+ surge activates ER-stress-superoxide-NO signalosome augmenting TNF-α production leading to apoptosis of Mycobacterium smegmatis-infected fish macrophages.Other primary literatureAnimalActiveScientific reports2019
Hussain MA, Datta D, Singh R, et al.
Elevated arterial shear rate increases indexes of endothelial cell autophagy and nitric oxide synthase activation in humans.Other primary literatureHumanActiveAmerican journal of physiology. Heart and circulatory physiology2019
Park SK, La Salle DT, Cerbie J, et al.
Antioxidant and Antiulcerogenic Activity of the Dry Extract of Pods of Libidibia ferrea Mart. ex Tul. (Fabaceae).Other primary literatureAnimalActiveOxidative medicine and cellular longevity2019
Prazeres LDKT, Aragão TP, Brito SA, et al.
Changes in Gastric Smooth Muscle Cell Contraction during Pregnancy: Effect of Estrogen.Other primary literatureAnimalActiveJournal of pregnancy2019
Al-Shboul OA, Al-Rshoud HJ, Al-Dwairi AN, et al.
S-nitrosylation of connexin43 hemichannels elicits cardiac stress-induced arrhythmias in Duchenne muscular dystrophy mice.Other primary literatureHuman & animalActiveJCI insight2019
Lillo MA, Himelman E, Shirokova N, et al.
Protective effect of apelin preconditioning in a rat model of hepatic ischemia reperfusion injury; possible interaction between the apelin/APJ system, Ang II/AT1R system and eNOS.Other primary literatureAnimalActiveUnited European gastroenterology journal2019
Sabry MM, Ramadan NM, Al Dreny BA, et al.
Dysregulation of the endothelial nitric oxide pathway is associated with airway inflammation in COPD.Other primary literatureHumanActiveRespiratory research2019
Csoma B, Bikov A, Nagy L, et al.
Angiotensin-(1-7) inhibits sodium transport via Mas receptor by increasing nitric oxide production in thick ascending limb.Other primary literatureAnimalActivePhysiological reports2019
Dibo P, Marañón RO, Chandrashekar K, et al.
Exhaled Breath Analysis in Obstructive Sleep Apnea Syndrome: A Review of the Literature.Systematic reviewHumanActiveMedicina (Kaunas, Lithuania)2019
Finamore P, Scarlata S, Cardaci V, et al.
Aristoteline, an Indole-Alkaloid, Induces Relaxation by Activating Potassium Channels and Blocking Calcium Channels in Isolated Rat Aorta.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2019
Romero F, Palacios J, Jofré I, et al.
Anti-Inflammatory Effect of Erinacine C on NO Production Through Down-Regulation of NF-κB and Activation of Nrf2-Mediated HO-1 in BV2 Microglial Cells Treated with LPS.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2019
Wang LY, Huang CS, Chen YH, et al.
(3β,16α)-3,16-Dihydroxypregn-5-en-20-one from the Twigs of Euonymus alatus (Thunb.) Sieb. Exerts Anti-Inflammatory Effects in LPS-Stimulated RAW-264.7 Macrophages.Other primary literatureHuman & animalActiveMolecules (Basel, Switzerland)2019
Lee S, Lee D, Baek SC, et al.
Nitric oxide represses the proliferation of Caco-2 cells by inducing S-G2/M cell cycle arrest.Other primary literatureUnknownActiveInternational journal of physiology, pathophysiology and pharmacology2019
Sakuma S, Ikeda Y, Inoue I, et al.
GPR68 Senses Flow and Is Essential for Vascular Physiology.Other primary literatureHuman & animalActiveCell2018
Xu J, Mathur J, Vessières E, et al.
Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation.Other primary literatureAnimalActiveCell reports2018
Lee CH, Kim HJ, Lee YS, et al.
Nitric oxide production by glomerular podocytes.Other primary literatureAnimalActiveNitric oxide : biology and chemistry2018
Palygin O, Ilatovskaya DV, Levchenko V, et al.
Structural Basis for Isoform Selective Nitric Oxide Synthase Inhibition by Thiophene-2-carboximidamides.Other primary literatureHuman & animalActiveBiochemistry2018
Li H, Evenson RJ, Chreifi G, et al.
A Ratiometric Acoustogenic Probe for in Vivo Imaging of Endogenous Nitric Oxide.Other primary literatureAnimalActiveJournal of the American Chemical Society2018
Reinhardt CJ, Zhou EY, Jorgensen MD, et al.
Structural basis for amino acid transport by the CAT family of SLC7 transporters.Other primary literatureAnimalActiveNature communications2018
Jungnickel KEJ, Parker JL, Newstead S
Polyoxygenated cyathane diterpenoids from the mushroom Cyathus africanus, and their neurotrophic and anti-neuroinflammatory activities.Other primary literatureAnimalActiveScientific reports2018
Wei J, Guo WH, Cao CY, et al.
Synthesis and biological evaluation of stilbene derivatives coupled to NO donors as potential antidiabetic agents.Other primary literatureAnimalActiveJournal of enzyme inhibition and medicinal chemistry2018
Wang B, Liu T, Wu Z, et al.
Vitamin A pretreatment protects NO-induced bovine mammary epithelial cells from oxidative stress by modulating Nrf2 and NF-κB signaling pathways.Other primary literatureAnimalActiveJournal of animal science2018
Shi HY, Yan SM, Guo YM, et al.
Mannan-induced Nos2 in macrophages enhances IL-17-driven psoriatic arthritis by innate lymphocytes.Other primary literatureHuman & animalActiveScience advances2018
Zhong J, Scholz T, Yau ACY, et al.
Characterization of CD38 in the major cell types of the heart: endothelial cells highly express CD38 with activation by hypoxia-reoxygenation triggering NAD(P)H depletion.Other primary literatureAnimalActiveAmerican journal of physiology. Cell physiology2018
Boslett J, Hemann C, Christofi FL, et al.
FAP Delineates Heterogeneous and Functionally Divergent Stromal Cells in Immune-Excluded Breast Tumors.Other primary literatureHuman & animalActiveCancer immunology research2018
Cremasco V, Astarita JL, Grauel AL, et al.
cGMP Imaging in Brain Slices Reveals Brain Region-Specific Activity of NO-Sensitive Guanylyl Cyclases (NO-GCs) and NO-GC Stimulators.Other primary literatureAnimalActiveInternational journal of molecular sciences2018
Peters S, Paolillo M, Mergia E, et al.
Bioactive Phenolic and Isocoumarin Glycosides from the Stems of Homalium paniculiflorum.Other primary literatureHuman & animalActiveMolecules (Basel, Switzerland)2018
Wu SY, Fu YH, Zhou Q, et al.
1,10-Secoguaianolides from Artemisia austro-yunnanensis and Their Anti-Inflammatory Effects.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2018
Liu L, Dai W, Xiang C, et al.
Carapanosins D-F from the Seeds of Andiroba (Carapa guianensis, Meliaceae) and Their Effects on LPS-Activated NO Production.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2018
Inoue T, Ohmori S, Kikuchi T, et al.
Synthesis of New Triarylpyrazole Derivatives Possessing Terminal Sulfonamide Moiety and Their Inhibitory Effects on PGE₂ and Nitric Oxide Productions in Lipopolysaccharide-Induced RAW 264.7 Macrophages.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2018
Abdel-Maksoud MS, El-Gamal MI, Gamal El-Din MM, et al.
The Inhibitory Effect of Ojeoksan on Early and Advanced Atherosclerosis.Other primary literatureHuman & animalActiveNutrients2018
Han BH, Seo CS, Yoon JJ, et al.
Effect of progesterone on nitric oxide/cyclic guanosine monophosphate signaling and contraction in gastric smooth muscle cells.Other primary literatureUnknownCorrectedBiomedical reports2018
Al-Shboul OA, Mustafa AG, Omar AA, et al.
Estrogen relaxes gastric muscle cells via a nitric oxide- and cyclic guanosine monophosphate-dependent mechanism: A sex-associated differential effect.Other primary literatureUnknownActiveExperimental and therapeutic medicine2018
Al-Shboul OA, Nazzal MS, Mustafa AG, et al.
Nitric oxide for respiratory failure in infants born at or near term.Meta-analysisHumanActiveThe Cochrane database of systematic reviews2017
Barrington KJ, Finer N, Pennaforte T, et al.
Inhaled nitric oxide for respiratory failure in preterm infants.Meta-analysisHumanActiveThe Cochrane database of systematic reviews2017
Barrington KJ, Finer N, Pennaforte T
A Topical Mitochondria-Targeted Redox-Cycling Nitroxide Mitigates Oxidative Stress-Induced Skin Damage.Other primary literatureHuman & animalActiveThe Journal of investigative dermatology2017
Brand RM, Epperly MW, Stottlemyer JM, et al.
Nitric oxide contributes to high-salt perception in a blood-sucking insect model.Other primary literatureAnimalActiveScientific reports2017
Cano A, Pontes G, Sfara V, et al.
Nitric oxide mediates apoptosis and mitochondrial dysfunction and plays a role in growth hormone deficiency by nivalenol in GH3 cells.Other primary literatureAnimalActiveScientific reports2017
Huang D, Cui L, Guo P, et al.
Amino acids as modulators of the European seabass, Dicentrarchus labrax, innate immune response: an in vitro approach.Other primary literatureAnimalActiveScientific reports2017
Azeredo R, Serra CR, Oliva-Teles A, et al.
Holophyllane A: A Triterpenoid Possessing an Unprecedented B-nor-3,4-seco-17,14-friedo-lanostane Architecture from Abies holophylla.Other primary literatureUnknownActiveScientific reports2017
Kim CS, Oh J, Subedi L, et al.
Dynamics of nitric oxide controlled by protein complex in bacterial system.Other primary literatureHumanActiveProceedings of the National Academy of Sciences of the United States of America2017
Terasaka E, Yamada K, Wang PH, et al.
Cavin-2 regulates the activity and stability of endothelial nitric-oxide synthase (eNOS) in angiogenesis.Other primary literatureAnimalActiveThe Journal of biological chemistry2017
Boopathy GTK, Kulkarni M, Ho SY, et al.
Vascular smooth muscle cell peroxisome proliferator-activated receptor γ protects against endothelin-1-induced oxidative stress and inflammation.Other primary literatureAnimalActiveJournal of hypertension2017
Idris-Khodja N, Ouerd S, Trindade M, et al.
S-Nitrosoglutathione Reductase Deficiency Confers Improved Survival and Neurological Outcome in Experimental Cerebral Malaria.Other primary literatureAnimalActiveInfection and immunity2017
Elphinstone RE, Besla R, Shikatani EA, et al.
Can endothelial hemoglobin-α regulate nitric oxide vasodilatory signaling?Other primary literatureHumanActiveAmerican journal of physiology. Heart and circulatory physiology2017
Parikh J, Kapela A, Tsoukias NM
Intracellular Angiotensin-II Interacts With Nuclear Angiotensin Receptors in Cardiac Fibroblasts and Regulates RNA Synthesis, Cell Proliferation, and Collagen Secretion.Other primary literatureAnimalActiveJournal of the American Heart Association2017
Tadevosyan A, Xiao J, Surinkaew S, et al.
Alamandine reduces leptin expression through the c-Src/p38 MAP kinase pathway in adipose tissue.Other primary literatureAnimalActivePloS one2017
Uchiyama T, Okajima F, Mogi C, et al.
Neuronal Nitric Oxide Synthase Contributes to PTZ Kindling Epilepsy-Induced Hippocampal Endoplasmic Reticulum Stress and Oxidative Damage.Other primary literatureUnknownActiveFrontiers in cellular neuroscience2017
Zhu X, Dong J, Han B, et al.
Zerumbone Alleviates Neuropathic Pain through the Involvement of l-Arginine-Nitric Oxide-cGMP-K⁺ ATP Channel Pathways in Chronic Constriction Injury in Mice Model.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2017
Zulazmi NA, Gopalsamy B, Min JC, et al.
Five New Limonoids from Peels of Satsuma Orange (Citrus reticulata).Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2017
Kikuchi T, Ueno Y, Hamada Y, et al.
Anti-Inflammatory Phenolic Acid Esters from the Roots and Rhizomes of Notopterygium incisium and Their Permeability in the Human Caco-2 Monolayer Cell Model.Other primary literatureHumanActiveMolecules (Basel, Switzerland)2017
Wu XW, Wei W, Yang XW, et al.
New Benzenoid Derivatives and Other Constituents from Lawsonia inermis with Inhibitory Activity against NO Production.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2017
Yang CS, Chen JJ, Huang HC, et al.
Anti-inflammatory effect of tribulusamide D isolated from Tribulus terrestris in lipopolysaccharide-stimulated RAW264.7 macrophages.Other primary literatureAnimalActiveMolecular medicine reports2017
Lee HH, Ahn EK, Hong SS, et al.
The Role of Nitric Oxide during Sonoreperfusion of Microvascular Obstruction.Other primary literatureHuman & animalActiveTheranostics2017
Yu FTH, Chen X, Straub AC, et al.
Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults.Meta-analysisHumanActiveThe Cochrane database of systematic reviews2016
Gebistorf F, Karam O, Wetterslev J, et al.
Elucidating nitric oxide synthase domain interactions by molecular dynamics.Other primary literatureHumanActiveProtein science : a publication of the Protein Society2016
Hollingsworth SA, Holden JK, Li H, et al.
Role of nitric oxide in the regulation of immune responses during rabies virus infection in mice.Other primary literatureUnknownActiveVirusdisease2016
Madhu BP, Singh KP, Saminathan M, et al.
Mathematical model for shear stress dependent NO and adenine nucleotide production from endothelial cells.Other primary literatureHumanActiveNitric oxide : biology and chemistry2016
Kirby PL, Buerk DG, Parikh J, et al.
Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation.Other primary literatureHuman & animalActiveMolecular psychiatry2016
Harraz MM, Tyagi R, Cortés P, et al.
Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics.Other primary literatureHuman & animalActiveNature communications2016
Eroglu E, Gottschalk B, Charoensin S, et al.
Mincle-mediated translational regulation is required for strong nitric oxide production and inflammation resolution.Other primary literatureAnimalActiveNature communications2016
Lee WB, Kang JS, Choi WY, et al.
The first description of complete invertebrate arginine metabolism pathways implies dose-dependent pathogen regulation in Apostichopus japonicus.Other primary literatureAnimalActiveScientific reports2016
Yina S, Chenghua L, Weiwei Z, et al.
Penicimenolides A-F, Resorcylic Acid Lactones from Penicillium sp., isolated from the Rhizosphere Soil of Panax notoginseng.Other primary literatureHumanActiveScientific reports2016
An YN, Zhang X, Zhang TY, et al.
Pruinosanones A-C, anti-inflammatory isoflavone derivatives from Caragana pruinosa.Other primary literatureAnimalActiveScientific reports2016
Zheng C, Wang L, Han T, et al.
Distal Hydrogen-bonding Interactions in Ligand Sensing and Signaling by Mycobacterium tuberculosis DosS.Other primary literatureUnknownActiveThe Journal of biological chemistry2016
Basudhar D, Madrona Y, Yukl ET, et al.
Controlling the decision to fight or flee: the roles of biogenic amines and nitric oxide in the cricket.Other primary literatureUnknownActiveCurrent zoology2016
Stevenson PA, Rillich J
Cardioprotection by H2S Donors: Nitric Oxide-Dependent and ‑Independent Mechanisms.Other primary literatureHuman & animalActiveThe Journal of pharmacology and experimental therapeutics2016
Chatzianastasiou A, Bibli SI, Andreadou I, et al.
Inhibition of endothelial nitric oxide synthase decreases breast cancer cell MDA-MB-231 adhesion to intact microvessels under physiological flows.Other primary literatureHuman & animalActiveAmerican journal of physiology. Heart and circulatory physiology2016
Zhang L, Zeng M, Fu BM
Depolarization of mitochondria in neurons promotes activation of nitric oxide synthase and generation of nitric oxide.Other primary literatureAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2016
Katakam PV, Dutta S, Sure VN, et al.
High salt induces autocrine actions of ET-1 on inner medullary collecting duct NO production via upregulated ETB receptor expression.Other primary literatureAnimalActiveAmerican journal of physiology. Regulatory, integrative and comparative physiology2016
Hyndman KA, Dugas C, Arguello AM, et al.
Angiotensin II-mediated hypertension impairs nitric oxide-induced NKCC2 inhibition in thick ascending limbs.Other primary literatureAnimalActiveAmerican journal of physiology. Renal physiology2016
Ramseyer VD, Ortiz PA, Carretero OA, et al.
Association of Common Variants in eNOS Gene with Primary Open Angle Glaucoma: A Meta-Analysis.Other primary literatureUnknownActiveJournal of ophthalmology2016
Xiang Y, Dong Y, Li X, et al.
Nitric oxide is involved in hydrogen gas-induced cell cycle activation during adventitious root formation in cucumber.Other primary literatureUnknownActiveBMC plant biology2016
Zhu Y, Liao W, Niu L, et al.
Phenolics from Garcinia mangostana alleviate exaggerated vasoconstriction in metabolic syndrome through direct vasodilatation and nitric oxide generation.Other primary literatureAnimalActiveBMC complementary and alternative medicine2016
Abdallah HM, El-Bassossy HM, Mohamed GA, et al.
Angiotensin II stimulates superoxide production by nitric oxide synthase in thick ascending limbs.Other primary literatureAnimalActivePhysiological reports2016
Gonzalez-Vicente A, Saikumar JH, Massey KJ, et al.
NITRIC OXIDE INHIBITORY ACTIVITY OF STRYCHNOS SPINOSA (LOGANIACEAE) LEAF EXTRACTS AND FRACTIONS.Other primary literatureHumanActiveAfrican journal of traditional, complementary, and alternative medicines : AJTCAM2016
Ai I, Jp D, Sa A, et al.
Oxidative Stress Genes, Antioxidants and Coronary Artery Disease in Type 2 Diabetes Mellitus.ReviewHuman & animalActiveCardiovascular & hematological agents in medicinal chemistry2016
Tibaut M, Petrovič D
Iodinated contrast media inhibit oxygen consumption in freshly isolated proximal tubular cells from elderly humans and diabetic rats: Influence of nitric oxide.Other primary literatureHuman & animalActiveUpsala journal of medical sciences2016
Liss P, Hansell P, Fasching A, et al.
Combined Cytological and Transcriptomic Analysis Reveals a Nitric Oxide Signaling Pathway Involved in Cold-Inhibited Camellia sinensis Pollen Tube Growth.Other primary literatureUnknownActiveFrontiers in plant science2016
Wang W, Sheng X, Shu Z, et al.
Hepatoprotective Limonoids from Andiroba (Carapa guianensis).Other primary literatureAnimalActiveInternational journal of molecular sciences2016
Ninomiya K, Miyazawa S, Ozeki K, et al.
Anti-Inflammatory Effects of Chloranthalactone B in LPS-Stimulated RAW264.7 Cells.Other primary literatureAnimalActiveInternational journal of molecular sciences2016
Li X, Shen J, Jiang Y, et al.
Role of Nitric Oxide and Hydrogen Sulfide in the Vasodilator Effect of Ursolic Acid and Uvaol from Black Cherry Prunus serotina Fruits.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2016
Luna-Vázquez FJ, Ibarra-Alvarado C, Rojas-Molina A, et al.
Sesquiterpenoids and Diterpenoids from the Wood of Cunninghamia konishii and Their Inhibitory Activities against NO Production.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2016
Chang CI, Chen CC, Chao CY, et al.
In Vitro Neuroprotective and Anti-Inflammatory Activities of Natural and Semi-Synthetic Spirosteroid Analogues.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2016
García-Pupo L, Zaldo-Castro A, Exarchou V, et al.
Three Novel Triterpenoids from Taraxacum officinale Roots.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2016
Kikuchi T, Tanaka A, Uriuda M, et al.
Protective effect of eNOS overexpression against ischemia/reperfusion injury in small-for-size liver transplantation.Other primary literatureUnknownActiveExperimental and therapeutic medicine2016
Zhang B, Liu QH, Zhou CJ, et al.
Expression of arginase I and inducible nitric oxide synthase in the peripheral blood and lymph nodes of HIV‑positive patients.Other primary literatureHumanActiveMolecular medicine reports2016
Zhang N, Deng J, Wu F, et al.
Nitric oxide from brain microvascular endothelial cells may initiate the compensatory response to mild hypoxia of astrocytes in a hypoxia-inducible factor-1α dependent manner.Other primary literatureUnknownActiveAmerican journal of translational research2016
Shi Q, Liu X, Wang N, et al.
Possible involvement of nitric oxide modulatory mechanism in the protective effect of retigabine against spinal nerve ligation-induced neuropathic pain.Other primary literatureAnimalActiveCellular and molecular neurobiology2015
Pottabathini R, Kumar A, Bhatnagar A, et al.
Methionine protects against hyperthermia-induced cell injury in cultured bovine mammary epithelial cells.Other primary literatureAnimalActiveCell stress & chaperones2015
Han ZY, Mu T, Yang Z
Insight into structural rearrangements and interdomain interactions related to electron transfer between flavin mononucleotide and heme in nitric oxide synthase: A molecular dynamics study.Other primary literatureHumanActiveJournal of inorganic biochemistry2015
Sheng Y, Zhong L, Guo D, et al.
Mechanistic studies of inactivation of inducible nitric oxide synthase by amidines.Other primary literatureAnimalActiveBiochemistry2015
Tang W, Li H, Poulos TL, et al.
Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Prodrugs as Drug Candidates for the Treatment of Ischemic Disorders: Insights into NO-Releasing Prodrug Biotransformation and Hemoglobin-NO Biochemistry.Other primary literatureHumanActiveBiochemistry2015
Xu GG, Deshpande TM, Ghatge MS, et al.
2-Aminopyridines with a Truncated Side Chain To Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity.Other primary literatureHuman & animalActiveJournal of medicinal chemistry2015
Kang S, Li H, Tang W, et al.
Structure-based design of bacterial nitric oxide synthase inhibitors.Other primary literatureUnknownActiveJournal of medicinal chemistry2015
Holden JK, Kang S, Hollingsworth SA, et al.
Effects of intravitreal injection of bevacizumab on nitric oxide levels.Other primary literatureAnimalActiveEye (London, England)2015
Dinc E, Yildirim O, Ayaz L, et al.
Dissecting structural and electronic effects in inducible nitric oxide synthase.Other primary literatureAnimalActiveThe Biochemical journal2015
Hannibal L, Page RC, Haque MM, et al.
Cross-talk Between Nitrate-Nitrite-NO and NO Synthase Pathways in Control of Vascular NO Homeostasis.Other primary literatureAnimalActiveAntioxidants & redox signaling2015
Carlström M, Liu M, Yang T, et al.
Intravenous and gastric cerium dioxide nanoparticle exposure disrupts microvascular smooth muscle signaling.Other primary literatureAnimalActiveToxicological sciences : an official journal of the Society of Toxicology2015
Minarchick VC, Stapleton PA, Fix NR, et al.
IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging.Other primary literatureAnimalActiveAging cell2015
Toth P, Tarantini S, Ashpole NM, et al.
Dynamics of enhanced mitochondrial respiration in female compared with male rat cerebral arteries.Other primary literatureAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2015
Rutkai I, Dutta S, Katakam PV, et al.
Angiotensin II-induced hypertension blunts thick ascending limb NO production by reducing NO synthase 3 expression and enhancing threonine 495 phosphorylation.Other primary literatureAnimalActiveAmerican journal of physiology. Renal physiology2015
Ramseyer VD, Gonzalez-Vicente A, Carretero OA, et al.
Ulcer healing and mechanism(s) of action involved in the gastroprotective activity of fractions obtained from Syngonanthus arthrotrichus and Syngonanthus bisulcatus.Other primary literatureHuman & animalActiveBMC complementary and alternative medicine2015
Batista LM, Lima GR, De Almeida AB, et al.
Potential biomarkers of fatigue identified by plasma metabolome analysis in rats.Other primary literatureAnimalActivePloS one2015
Kume S, Yamato M, Tamura Y, et al.
Comparative proteomic analysis of the molecular responses of mouse macrophages to titanium dioxide and copper oxide nanoparticles unravels some toxic mechanisms for copper oxide nanoparticles in macrophages.Other primary literatureAnimalActivePloS one2015
Triboulet S, Aude-Garcia C, Armand L, et al.
Tumor Necrosis Factor (TNF) -308G>A, Nitric Oxide Synthase 3 (NOS3) +894G>T Polymorphisms and Migraine Risk: A Meta-Analysis.Meta-analysisHumanActivePloS one2015
Chen M, Tang W, Hou L, et al.
Preventive Effects of Tocotrienol on Stress-Induced Gastric Mucosal Lesions and Its Relation to Oxidative and Inflammatory Biomarkers.Other primary literatureAnimalActivePloS one2015
Nur Azlina MF, Kamisah Y, Chua KH, et al.
Soluble beta amyloid evokes alteration in brain norepinephrine levels: role of nitric oxide and interleukin-1.Other primary literatureUnknownActiveFrontiers in neuroscience2015
Morgese MG, Colaianna M, Mhillaj E, et al.
Carapanolides T-X from Carapa guianensis (Andiroba) Seeds.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2015
Miyake T, Ishimoto S, Ishimatsu N, et al.
Pyranocoumarins from Root Extracts of Peucedanum praeruptorum Dunn with Multidrug Resistance Reversal and Anti-Inflammatory Activities.Other primary literatureHuman & animalActiveMolecules (Basel, Switzerland)2015
Lee J, Lee YJ, Kim J, et al.
Anti-Inflammatory Effect of Angelica gigas via Heme Oxygenase (HO)-1 Expression.Other primary literatureAnimalActiveNutrients2015
Cho JH, Kwon JE, Cho Y, et al.
Flavonoids isolated from Lespedeza cuneata G. Don and their inhibitory effects on nitric oxide production in lipopolysaccharide-stimulated BV-2 microglia cells.Other primary literatureUnknownActivePharmacognosy magazine2015
Yoo G, Park SJ, Lee TH, et al.
Comparison of inducible nitric oxide synthase activity in pancreatic islets of young and aged rats.Other primary literatureUnknownActiveIranian journal of basic medical sciences2015
Farrokhfall K, Hashtroudi MS, Ghasemi A, et al.
Nitric oxide regulation of Na, K-ATPase activity in ocular ciliary epithelium involves Src family kinase.Other primary literatureAnimalActiveJournal of cellular physiology2014
Shahidullah M, Mandal A, Wei G, et al.
Increased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesity.Other primary literatureAnimalActiveCell2014
Lee YS, Kim JW, Osborne O, et al.
S-nitrosothiol signaling regulates liver development and improves outcome following toxic liver injury.Other primary literatureAnimalActiveCell reports2014
Cox AG, Saunders DC, Kelsey PB Jr, et al.
The extreme anterior domain is an essential craniofacial organizer acting through Kinin-Kallikrein signaling.Other primary literatureAnimalActiveCell reports2014
Jacox L, Sindelka R, Chen J, et al.
Holoenzyme structures of endothelial nitric oxide synthase - an allosteric role for calmodulin in pivoting the FMN domain for electron transfer.Other primary literatureAnimalActiveJournal of structural biology2014
Volkmann N, Martásek P, Roman LJ, et al.
Metaplastic effects of subanesthetic ketamine on CA1 hippocampal function.Other primary literatureAnimalActiveNeuropharmacology2014
Izumi Y, Zorumski CF
Identification of a negative feedback loop in biological oxidant formation fegulated by 4-hydroxy-2-(E)-nonenal.Other primary literatureAnimalActiveRedox biology2014
Gatbonton-Schwager TN, Sadhukhan S, Zhang GF, et al.
Nitric oxide synthase inhibitors that interact with both heme propionate and tetrahydrobiopterin show high isoform selectivity.Other primary literatureHumanActiveJournal of medicinal chemistry2014
Kang S, Tang W, Li H, et al.
Hydrogen sulfide regulates Ca(2+) homeostasis mediated by concomitantly produced nitric oxide via a novel synergistic pathway in exocrine pancreas.Other primary literatureAnimalActiveAntioxidants & redox signaling2014
Moustafa A, Habara Y
Cotransplantation with myeloid-derived suppressor cells protects cell transplants: a crucial role of inducible nitric oxide synthase.Other primary literatureAnimalActiveTransplantation2014
Arakawa Y, Qin J, Chou HS, et al.
Anti-arthritis effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal are mediated by inhibition of the STAT3 pathway.Other primary literatureHuman & animalActiveBritish journal of pharmacology2014
Ban JO, Kim DH, Lee HP, et al.
Chocolate--guilty pleasure or healthy supplement?ReviewHumanActiveJournal of clinical hypertension (Greenwich, Conn.)2014
Latham LS, Hensen ZK, Minor DS
Nitrergic neuromuscular transmission in the mouse internal anal sphincter is accomplished by multiple pathways and postjunctional effector cells.Other primary literatureAnimalActiveAmerican journal of physiology. Gastrointestinal and liver physiology2014
Cobine CA, Sotherton AG, Peri LE, et al.
Multitracer stable isotope quantification of arginase and nitric oxide synthase activity in a mouse model of pseudomonas lung infection.Other primary literatureAnimalActiveMediators of inflammation2014
Grasemann H, Jaecklin T, Mehl A, et al.
Resveratrol increases nitric oxide production in the rat thick ascending limb via Ca2+/calmodulin.Other primary literatureAnimalActivePloS one2014
Gonzalez-Vicente A, Cabral PD, Garvin JL
Nitric oxide transport in normal human thoracic aorta: effects of hemodynamics and nitric oxide scavengers.Other primary literatureHumanActivePloS one2014
Liu X, Wang Z, Zhao P, et al.
Crucial role for neuronal nitric oxide synthase in early microcirculatory derangement and recipient survival following murine pancreas transplantation.Other primary literatureAnimalActivePloS one2014
Cardini B, Watschinger K, Hermann M, et al.
Metallothionein-1 and nitric oxide expression are inversely correlated in a murine model of Chagas disease.Other primary literatureAnimalActiveMemorias do Instituto Oswaldo Cruz2014
Gonzalez-Mejia ME, Torres-Rasgado E, Porchia LM, et al.
Endothelial nitric oxide synthase (eNOS) 4b/a gene polymorphisms and coronary artery disease: evidence from a meta-analysis.Meta-analysisHumanActiveInternational journal of molecular sciences2014
Yang Y, Du K, Du K, et al.
Maritime halophyte species from southern Portugal as sources of bioactive molecules.Other primary literatureHuman & animalActiveMarine drugs2014
Rodrigues MJ, Gangadhar KN, Vizetto-Duarte C, et al.
Sesquiterpenes from the Brazilian red alga Laurencia dendroidea J. Agardh.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2014
da Silva Machado FL, Ventura TL, Gestinari LM, et al.
Five withanolides from the leaves of Datura metel L. and their inhibitory effects on nitric oxide production.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2014
Yang BY, Guo R, Li T, et al.
Dehydroabietic acid isolated from Commiphora opobalsamum causes endothelium-dependent relaxation of pulmonary artery via PI3K/Akt-eNOS signaling pathway.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2014
Gao W, Dong X, Xie N, et al.
Synthesis and sar study of diarylpentanoid analogues as new anti-inflammatory agents.Other primary literatureAnimalActiveMolecules (Basel, Switzerland)2014
Leong SW, Faudzi SM, Abas F, et al.
TI-I-174, a Synthetic Chalcone Derivative, Suppresses Nitric Oxide Production in Murine Macrophages via Heme Oxygenase-1 Induction and Inhibition of AP-1.Other primary literatureUnknownActiveBiomolecules & therapeutics2014
Kim MJ, Kadayat T, Kim DE, et al.
Nω-NITRO-Nω'-SUBSTITUTED GUANIDINES: A SIMPLE CLASS OF NITRIC OXIDE SYNTHASE INHIBITORS.Other primary literatureUnknownActiveModern research in inflammation2014
Guillon CD, Wisnoski DD, Saxena J, et al.
Inducible nitric oxide synthase inhibition increases MMP-2 activity leading to imbalance between extracellular matrix deposition and degradation after polypropylene mesh implant.Other primary literatureAnimalActiveJournal of biomedical materials research. Part A2013
Souza-Pinto FJ, Moretti AI, Cury V, et al.
Methylene blue for distributive shock: a potential new use of an old antidote.ReviewHuman & animalActiveJournal of medical toxicology : official journal of the American College of Medical Toxicology2013
Jang DH, Nelson LS, Hoffman RS
Modulation of NO and ROS production by AdiNOS transduced vascular cells through supplementation with L-Arg and BH4: implications for gene therapy of restenosis.Other primary literatureAnimalActiveAtherosclerosis2013
Forbes SP, Alferiev IS, Chorny M, et al.
Behavioral effects of cocaine mediated by nitric oxide-GAPDH transcriptional signaling.Other primary literatureAnimalActiveNeuron2013
Xu R, Serritella AV, Sen T, et al.
Ligand access to the active site in Thermus thermophilus ba(3) and bovine heart aa(3) cytochrome oxidases.Other primary literatureAnimalActiveBiochemistry2013
McDonald W, Funatogawa C, Li Y, et al.
Molecular responses of mouse macrophages to copper and copper oxide nanoparticles inferred from proteomic analyses.Other primary literatureAnimalActiveMolecular & cellular proteomics : MCP2013
Triboulet S, Aude-Garcia C, Carrière M, et al.
Coronary endothelial dysfunction and mitochondrial reactive oxygen species in type 2 diabetic mice.Other primary literatureHuman & animalActiveAmerican journal of physiology. Cell physiology2013
Cho YE, Basu A, Dai A, et al.
Insights into the arginine paradox: evidence against the importance of subcellular location of arginase and eNOS.Other primary literatureAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2013
Elms S, Chen F, Wang Y, et al.
Anandamide inhibits transport-related oxygen consumption in the loop of Henle by activating CB1 receptors.Other primary literatureAnimalActiveAmerican journal of physiology. Renal physiology2013
Silva GB, Atchison DK, Juncos LI, et al.
Sildenafil (Viagra) protective effects on neuroinflammation: the role of iNOS/NO system in an inflammatory demyelination model.Other primary literatureAnimalActiveMediators of inflammation2013
Raposo C, Nunes AK, Luna RL, et al.
Pharmacological treatment for hepatopulmonary syndrome.ReviewHumanActiveBioMed research international2013
Eshraghian A, Kamyab AA, Yoon SK
The opposing roles of nitric oxide and cGMP in the age-associated decline in rat testicular steroidogenesis.Other primary literatureAnimalActiveEndocrinology2013
Sokanovic SJ, Baburski AZ, Janjic MM, et al.
Properties of immature myeloid progenitors with nitric-oxide-dependent immunosuppressive activity isolated from bone marrow of tumor-free mice.Other primary literatureAnimalActivePloS one2013
Forghani P, Harris W, Giver CR, et al.
TNFα-mediated liver destruction by Kupffer cells and Ly6Chi monocytes during Entamoeba histolytica infection.Other primary literatureAnimalActivePLoS pathogens2013
Helk E, Bernin H, Ernst T, et al.
Anti-inflammatory activity of N-(3-florophenyl)ethylcaffeamide in mice.Other primary literatureAnimalActiveInternational journal of molecular sciences2013
Liao JC, Tsai JC, Peng WH, et al.
Antioxidant properties of cis-Z,Z'-3a.7a',7a.3a'-dihydroxyligustilide on human umbilical vein endothelial cells in vitro.Other primary literatureHumanActiveMolecules (Basel, Switzerland)2013
Li W, Wu Y, Liu X, et al.
Bioactive compounds from the roots of Asiasarum heterotropoides.Other primary literatureHuman & animalActiveMolecules (Basel, Switzerland)2013
Lee J, Lee YJ, Oh SM, et al.
Nitric Oxide Synthase is Necessary for Normal Urogenital Development.Other primary literatureUnknownActiveAndrology : open access2013
Bond C, Cakir OO, McVary KT, et al.
Polymer-Based Nitric Oxide Therapies: Recent Insights for Biomedical Applications.Other primary literatureUnknownActiveAdvanced functional materials2012
Jen MC, Serrano MC, van Lith R, et al.
Altered angiogenesis in caveolin-1 gene-deficient mice is restored by ablation of endothelial nitric oxide synthase.Other primary literatureAnimalActiveThe American journal of pathology2012
Morais C, Ebrahem Q, Anand-Apte B, et al.
Cytomegalovirus impairs antiviral CD8+ T cell immunity by recruiting inflammatory monocytes.Other primary literatureAnimalActiveImmunity2012
Daley-Bauer LP, Wynn GM, Mocarski ES
Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations.Other primary literatureUnknownActiveJournal of the American Chemical Society2012
Huang H, Ji H, Li H, et al.
Nitrative stress in cerebral endothelium is mediated by mGluR5 in hyperhomocysteinemia.Other primary literatureAnimalActiveJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2012
Mayo JN, Beard RS Jr, Price TO, et al.
Rational design of a fluorescent NADPH derivative imaging constitutive nitric-oxide synthases upon two-photon excitation.Other primary literatureHumanActiveProceedings of the National Academy of Sciences of the United States of America2012
Li Y, Wang H, Tarus B, et al.
Inducible nitric oxide synthase contributes to immune dysfunction following trauma.Other primary literatureAnimalActiveShock (Augusta, Ga.)2012
Darwiche SS, Pfeifer R, Menzel C, et al.
Effect of nitric oxide donors S-nitroso-N-acetyl-DL-penicillamine, spermine NONOate and propylamine propylamine NONOate on intracellular pH in cardiomyocytes.Other primary literatureAnimalActiveClinical and experimental pharmacology & physiology2012
Pravdic D, Vladic N, Cavar I, et al.
Uncoupling of eNOS causes superoxide anion production and impairs NO signaling in the cerebral microvessels of hph-1 mice.Other primary literatureAnimalActiveJournal of neurochemistry2012
Santhanam AV, d'Uscio LV, Smith LA, et al.
Ascorbate protects against vascular leakage in cecal ligation and puncture-induced septic peritonitis.Other primary literatureAnimalActiveAmerican journal of physiology. Regulatory, integrative and comparative physiology2012
Zhou G, Kamenos G, Pendem S, et al.
Angiotensin II type 2 receptor-coupled nitric oxide production modulates free radical availability and voltage-gated Ca2+ currents in NTS neurons.Other primary literatureAnimalActiveAmerican journal of physiology. Regulatory, integrative and comparative physiology2012
Wang G, Coleman CG, Glass MJ, et al.
Low micromolar intravascular cell-free hemoglobin concentration affects vascular NO bioavailability in sickle cell disease: a computational analysis.Other primary literatureHumanActiveJournal of applied physiology (Bethesda, Md. : 1985)2012
Deonikar P, Kavdia M
Relaxin increases human endothelial progenitor cell NO and migration and vasculogenesis in mice.Other primary literatureHuman & animalActiveBlood2012
Segal MS, Sautina L, Li S, et al.
Testosterone deficiency accelerates neuronal and vascular aging of SAMP8 mice: protective role of eNOS and SIRT1.Other primary literatureHuman & animalActivePloS one2012
Ota H, Akishita M, Akiyoshi T, et al.
Proteomic identification of S-nitrosylated Golgi proteins: new insights into endothelial cell regulation by eNOS-derived NO.Other primary literatureHuman & animalActivePloS one2012
Sangwung P, Greco TM, Wang Y, et al.
The dose-dependent immunoregulatory effects of the nitric oxide synthase inhibitor N(G)-nitro-L-arginine methyl ester in rats with sub-acute peritonitis.Other primary literatureHuman & animalActivePloS one2012
Hsiao CC, Lee CH, Tsao LY, et al.
Inhibition of endothelial- and neuronal-type, but not inducible-type, nitric oxide synthase by the oxidized cholesterol metabolite secosterol aldehyde: Implications for vascular and neurodegenerative diseases.Other primary literatureUnknownActiveJournal of clinical biochemistry and nutrition2012
Lai YL, Tomono S, Miyoshi N, et al.
Rat mesenchymal stromal cells inhibit T cell proliferation but not cytokine production through inducible nitric oxide synthase.Other primary literatureUnknownActiveFrontiers in immunology2012
Zinöcker S, Vaage JT
Expression of monoamine transporters, nitric oxide synthase 3, and neurotrophin genes in antidepressant-stimulated astrocytes.Other primary literatureUnknownActiveFrontiers in psychiatry2012
Kittel-Schneider S, Kenis G, Schek J, et al.
An efficient total synthesis of a potent anti-inflammatory agent, benzocamphorin F, and its anti-inflammatory activity.Other primary literatureAnimalActiveInternational journal of molecular sciences2012
Liao YR, Kuo PC, Liang JW, et al.
Chemical constituents from Andrographis echioides and their anti-inflammatory activity.Other primary literatureAnimalActiveInternational journal of molecular sciences2012
Shen DY, Juang SH, Kuo PC, et al.
Tumor-expressed inducible nitric oxide synthase controls induction of functional myeloid-derived suppressor cells through modulation of vascular endothelial growth factor release.Other primary literatureAnimalActiveJournal of immunology (Baltimore, Md. : 1950)2012
Jayaraman P, Parikh F, Lopez-Rivera E, et al.
Up-regulation of thromboxane A₂ impairs cerebrovascular eNOS function in aging atherosclerotic mice.Other primary literatureHuman & animalActivePflugers Archiv : European journal of physiology2011
Drouin A, Farhat N, Bolduc V, et al.
Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents.Other primary literatureHumanActiveBioorganic & medicinal chemistry2011
Shen L, Park EJ, Kondratyuk TP, et al.
Effects of T- and R-state stabilization on deoxyhemoglobin-nitrite reactions and stimulation of nitric oxide signaling.Other primary literatureAnimalActiveNitric oxide : biology and chemistry2011
Cantu-Medellin N, Vitturi DA, Rodriguez C, et al.
Design, synthesis, and biological evaluation of 3,4-dihydroquinolin-2(1H)-one and 1,2,3,4-tetrahydroquinoline-based selective human neuronal nitric oxide synthase (nNOS) inhibitors.Other primary literatureHuman & animalActiveJournal of medicinal chemistry2011
Ramnauth J, Speed J, Maddaford SP, et al.
Bioactive compounds from the fern Lepisorus contortus.Other primary literatureHuman & animalActiveJournal of natural products2011
Yang JH, Kondratyuk TP, Jermihov KC, et al.
Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes.Other primary literatureAnimalActiveNature immunology2011
Lukacs-Kornek V, Malhotra D, Fletcher AL, et al.
Caveolin-1-eNOS signaling promotes p190RhoGAP-A nitration and endothelial permeability.Other primary literatureHuman & animalActiveThe Journal of cell biology2011
Siddiqui MR, Komarova YA, Vogel SM, et al.
Phosphodiesterase-5A (PDE5A) is localized to the endothelial caveolae and modulates NOS3 activity.Other primary literatureHuman & animalActiveCardiovascular research2011
Gebska MA, Stevenson BK, Hemnes AR, et al.
Electroacupuncture Zusanli (ST36) on Release of Nitric Oxide in the Gracile Nucleus and Improvement of Sensory Neuropathies in Zucker Diabetic Fatty Rats.Other primary literatureUnknownActiveEvidence-based complementary and alternative medicine : eCAM2011
Rong PJ, Ma SX
A2B adenosine receptors inhibit superoxide production from mitochondrial complex I in rabbit cardiomyocytes via a mechanism sensitive to Pertussis toxin.Other primary literatureHuman & animalActiveBritish journal of pharmacology2011
Yang X, Xin W, Yang XM, et al.
Nitric oxide synthase 3 deficiency limits adverse ventricular remodeling after pressure overload in insulin resistance.Other primary literatureAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2011
Kurtz B, Thibault HB, Raher MJ, et al.
NMDA receptors in hippocampal GABAergic synapses and their role in nitric oxide signaling.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2011
Szabadits E, Cserép C, Szonyi A, et al.
Tumor-infiltrating, myeloid-derived suppressor cells inhibit T cell activity by nitric oxide production in an intracranial rat glioma + vaccination model.Other primary literatureHuman & animalActiveJournal of neuroimmunology2010
Jia W, Jackson-Cook C, Graf MR
Differential activation of NF-κB and nitric oxide in lymphocytes regulates in vitro and in vivo radiosensitivity.Other primary literatureAnimalActiveMutation research2010
Sharma D, Sandur SK, Rashmi R, et al.
A computational model for nitric oxide, nitrite and nitrate biotransport in the microcirculation: effect of reduced nitric oxide consumption by red blood cells and blood velocity.Other primary literatureHuman & animalActiveMicrovascular research2010
Deonikar P, Kavdia M
PRODUCTION OF NITRIC OXIDE WITHIN THE APLYSIA CALIFORNICA NERVOUS SYSTEM.Other primary literatureUnknownActiveACS chemical neuroscience2010
Ye X, Xie F, Romanova EV, et al.
Exploration of the active site of neuronal nitric oxide synthase by the design and synthesis of pyrrolidinomethyl 2-aminopyridine derivatives.Other primary literatureAnimalActiveJournal of medicinal chemistry2010
Ji H, Delker SL, Li H, et al.
The contribution of L-arginine to the neurotoxicity of recombinant tissue plasminogen activator following cerebral ischemia: a review of rtPA neurotoxicity.ReviewHuman & animalActiveJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2010
Harston GW, Sutherland BA, Kennedy J, et al.
Acute and chronic exposure to shear stress have opposite effects on endothelial permeability to macromolecules.Other primary literatureAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2010
Warboys CM, Eric Berson R, Mann GE, et al.
Shear stress increases nitric oxide production in thick ascending limbs.Other primary literatureAnimalActiveAmerican journal of physiology. Renal physiology2010
Cabral PD, Hong NJ, Garvin JL
Nuclear angiotensin-(1-7) receptor is functionally coupled to the formation of nitric oxide.Other primary literatureAnimalActiveAmerican journal of physiology. Renal physiology2010
Gwathmey TM, Westwood BM, Pirro NT, et al.
Chronic intermittent hypoxia induces NMDA receptor-dependent plasticity and suppresses nitric oxide signaling in the mouse hypothalamic paraventricular nucleus.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2010
Coleman CG, Wang G, Park L, et al.
Piper sarmentosum increases nitric oxide production in oxidative stress: a study on human umbilical vein endothelial cells.Other primary literatureHumanActiveClinics (Sao Paulo, Brazil)2010
Ugusman A, Zakaria Z, Hui CK, et al.
Bone marrow cell recruitment mediated by inducible nitric oxide synthase/stromal cell-derived factor-1alpha signaling repairs the acoustically damaged cochlear blood-labyrinth barrier.Other primary literatureAnimalActiveThe American journal of pathology2010
Dai M, Yang Y, Omelchenko I, et al.
Pulsed electromagnetic field stimulates cellular proliferation in human intervertebral disc cells.Other primary literatureHumanActiveYonsei medical journal2010
Lee HM, Lee HM, Kwon UH, et al.
The mechanism of (R,R) ZX-5 on increasing NO release.Other primary literatureHumanActiveInternational journal of molecular sciences2010
Xu HM, Wei J, Pan L, et al.
CTL induction of tumoricidal nitric oxide production by intratumoral macrophages is critical for tumor elimination.Other primary literatureAnimalActiveJournal of immunology (Baltimore, Md. : 1950)2010
Vicetti Miguel RD, Cherpes TL, Watson LJ, et al.
Discovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping.Other primary literatureAnimalActiveJournal of medicinal chemistry2009
Ji H, Li H, Martásek P, et al.
Effects of estrogen on postischemic pial artery reactivity to ADP.Other primary literatureAnimalActiveMicrocirculation (New York, N.Y. : 1994)2009
Li M, Zeynalov E, Li X, et al.
Superoxide signaling in pain is independent of nitric oxide signaling.Other primary literatureAnimalActiveNeuroreport2009
Kim HY, Wang J, Lu Y, et al.
Estradiol induces physical association of neuronal nitric oxide synthase with NMDA receptor and promotes nitric oxide formation via estrogen receptor activation in primary neuronal cultures.Other primary literatureAnimalActiveJournal of neurochemistry2009
d'Anglemont de Tassigny X, Campagne C, Steculorum S, et al.
Enhancement of the anti-inflammatory and anti-arthritic effects of theophylline by a low dose of a nitric oxide donor or non-specific nitric oxide synthase inhibitor.Other primary literatureAnimalActiveBritish journal of pharmacology2009
Gomaa A, Elshenawy M, Afifi N, et al.
Alcohol stimulates ciliary motility of isolated airway axonemes through a nitric oxide, cyclase, and cyclic nucleotide-dependent kinase mechanism.Other primary literatureAnimalActiveAlcoholism, clinical and experimental research2009
Sisson JH, Pavlik JA, Wyatt TA
Radioprotection in normal tissue and delayed tumor growth by blockade of CD47 signaling.Other primary literatureHuman & animalActiveScience translational medicine2009
Maxhimer JB, Soto-Pantoja DR, Ridnour LA, et al.
Role of tetrahydrobiopterin in resistance to myocardial ischemia in Brown Norway and Dahl S rats.Other primary literatureAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2009
An J, Du J, Wei N, et al.
sGC(alpha)1(beta)1 attenuates cardiac dysfunction and mortality in murine inflammatory shock models.Other primary literatureAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2009
Buys ES, Cauwels A, Raher MJ, et al.
Reduction of electrical coupling between microvascular endothelial cells by NO depends on connexin37.Other primary literatureAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2009
McKinnon RL, Bolon ML, Wang HX, et al.
Akt1 mediates purinergic-dependent NOS3 activation in thick ascending limbs.Other primary literatureAnimalActiveAmerican journal of physiology. Renal physiology2009
Silva GB, Garvin JL
Extracellular ATP inhibits transport in medullary thick ascending limbs: role of P2X receptors.Other primary literatureAnimalActiveAmerican journal of physiology. Renal physiology2009
Silva GB, Garvin JL
ADMA injures the glomerular filtration barrier: role of nitric oxide and superoxide.Other primary literatureAnimalActiveAmerican journal of physiology. Renal physiology2009
Sharma M, Zhou Z, Miura H, et al.
PP2B-dependent NO production in the medullary thick ascending limb during diabetes.Other primary literatureAnimalActiveAmerican journal of physiology. Renal physiology2009
Foster JM, Carmines PK, Pollock JS
Nuclear angiotensin II type 2 (AT2) receptors are functionally linked to nitric oxide production.Other primary literatureAnimalActiveAmerican journal of physiology. Renal physiology2009
Gwathmey TM, Shaltout HA, Pendergrass KD, et al.
Nitric oxide production by the human intestinal microbiota by dissimilatory nitrate reduction to ammonium.Other primary literatureHumanActiveJournal of biomedicine & biotechnology2009
Vermeiren J, Van de Wiele T, Verstraete W, et al.
Metallothionein abrogates GTP cyclohydrolase I inhibition-induced cardiac contractile and morphological defects: role of mitochondrial biogenesis.Other primary literatureAnimalActiveHypertension (Dallas, Tex. : 1979)2009
Ceylan-Isik AF, Guo KK, Carlson EC, et al.
Angiotensin II decreases nitric oxide synthase 3 expression via nitric oxide and superoxide in the thick ascending limb.Other primary literatureAnimalActiveHypertension (Dallas, Tex. : 1979)2009
Ramseyer VD, Garvin JL
alpha1G-dependent T-type Ca2+ current antagonizes cardiac hypertrophy through a NOS3-dependent mechanism in mice.Other primary literatureAnimalActiveThe Journal of clinical investigation2009
Nakayama H, Bodi I, Correll RN, et al.
A non-cytosolic protein of Trypanosoma evansi induces CD45-dependent lymphocyte death.Other primary literatureAnimalActivePloS one2009
Antoine-Moussiaux N, Cornet A, Cornet F, et al.
Suppression of spreading depression-like events in locusts by inhibition of the NO/cGMP/PKG pathway.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2009
Armstrong GA, Rodgers CI, Money TG, et al.
Normal responses to restraint stress in mice lacking the gene for neuronal nitric oxide synthase.Other primary literatureAnimalActiveJournal of andrology2009
Weissman BA, Sottas CM, Holmes M, et al.
Oxidative stress and compartment of gene expression determine proatherosclerotic effects of inducible nitric oxide synthase.Other primary literatureAnimalActiveThe American journal of pathology2009
Ponnuswamy P, Ostermeier E, Schröttle A, et al.
Protective effects of electroacupuncture on acetylsalicylic acid-induced acute gastritis in rats.Other primary literatureAnimalActiveWorld journal of gastroenterology2009
Hwang HS, Han KJ, Ryu YH, et al.
Local loperamide inhibits thermal hyperalgesia but not mechanical allodynia induced by intratibial inoculation of melanoma cells in mice.Other primary literatureAnimalActiveCellular and molecular neurobiology2008
Curto-Reyes V, Juárez L, García-Pérez E, et al.
Nitrosothiol reactivity profiling identifies S-nitrosylated proteins with unexpected stability.Other primary literatureHuman & animalActiveChemistry & biology2008
Paige JS, Xu G, Stancevic B, et al.
Secondary hyperalgesia in the rat first degree burn model is independent of spinal cyclooxygenase and nitric oxide synthase.Other primary literatureAnimalActiveEuropean journal of pharmacology2008
Sorkin LS, Doom CM, Maruyama KP, et al.
Long-term nitric oxide deficiency causes muscarinic supersensitivity and reduces beta(3)-adrenoceptor-mediated relaxation, causing rat detrusor overactivity.Other primary literatureAnimalActiveBritish journal of pharmacology2008
Mónica FZ, Bricola AA, Báu FR, et al.
Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.Other primary literatureHuman & animalActiveNature chemical biology2008
Garcin ED, Arvai AS, Rosenfeld RJ, et al.
Nitric oxide-dependent proteasomal degradation of cytochrome P450 2B proteins.Other primary literatureAnimalActiveThe Journal of biological chemistry2008
Lee CM, Kim BY, Li L, et al.
Acute effect of manganese on hypothalamic luteinizing hormone releasing hormone secretion in adult male rats: involvement of specific neurotransmitter systems.Other primary literatureAnimalActiveToxicological sciences : an official journal of the Society of Toxicology2008
Prestifilippo JP, Fernández-Solari J, De Laurentiis A, et al.
Role of endothelial nitric oxide synthase-derived nitric oxide in activation and dysfunction of cerebrovascular endothelial cells during early onsets of sepsis.Other primary literatureAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2008
Handa O, Stephen J, Cepinskas G
Interaction of nitric oxide, 20-HETE, and EETs during functional hyperemia in whisker barrel cortex.Other primary literatureAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2008
Liu X, Li C, Falck JR, et al.
Nitric oxide is a key component in inflammation-accelerated tumorigenesis.Other primary literatureAnimalActiveCancer research2008
Hussain SP, He P, Subleski J, et al.
Opposing effects of D-aspartic acid and nitric oxide on tuning of testosterone production in mallard testis during the reproductive cycle.Other primary literatureAnimalActiveReproductive biology and endocrinology : RB&E2008
Di Fiore MM, Lamanna C, Assisi L, et al.
Cationic amino acid transporter-2 regulates immunity by modulating arginase activity.Other primary literatureAnimalActivePLoS pathogens2008
Thompson RW, Pesce JT, Ramalingam T, et al.
Nitric oxide effects on the function of aged cells ex vivo and in vivo.Other primary literatureAnimalActiveIn vivo (Athens, Greece)2008
Reed MJ, Eyman D, Karres N
Nitric oxide for preventing pre-eclampsia and its complications.Meta-analysisHumanActiveThe Cochrane database of systematic reviews2007
Meher S, Duley L
Selective L-nitroargininylaminopyrrolidine and L-nitroargininylaminopiperidine neuronal nitric oxide synthase inhibitors.Other primary literatureUnknownActiveBioorganic & medicinal chemistry2007
Seo J, Martásek P, Roman LJ, et al.
Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia.Other primary literatureAnimalActiveJournal of neuroimmunology2007
Schell JB, Crane CA, Smith MF Jr, et al.
Structure-based design and synthesis of N(omega)-nitro-L-arginine-containing peptidomimetics as selective inhibitors of neuronal nitric oxide synthase. Displacement of the heme structural water.Other primary literatureUnknownActiveJournal of medicinal chemistry2007
Seo J, Igarashi J, Li H, et al.
Increase in exhaled nitric oxide and protective role of the nitric oxide system in experimental pulmonary embolism.Other primary literatureAnimalActiveBritish journal of pharmacology2007
Nilsson KF, Gustafsson LE, Adding LC, et al.
Nitric oxide inhibits Shiga-toxin synthesis by enterohemorrhagic Escherichia coli.Other primary literatureHumanActiveProceedings of the National Academy of Sciences of the United States of America2007
Vareille M, de Sablet T, Hindré T, et al.
peroxisome proliferator-activated receptor alpha activation-mediated regulation of endothelin-1 production via nitric oxide and protein kinase C signaling pathways in piglet cerebral microvascular endothelial cell culture.Other primary literatureAnimalActiveThe Journal of pharmacology and experimental therapeutics2007
Yakubu MA, Nsaif RH, Oyekan AO
Nitric oxide and peroxynitrite in health and disease.ReviewHuman & animalActivePhysiological reviews2007
Pacher P, Beckman JS, Liaudet L
Genetic knockout and pharmacologic inhibition of neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice.Other primary literatureAnimalActiveMolecular pain2007
Guan Y, Yaster M, Raja SN, et al.
Coupling of neuronal nitric oxide synthase to NMDA receptors via postsynaptic density-95 depends on estrogen and contributes to the central control of adult female reproduction.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2007
d'Anglemont de Tassigny X, Campagne C, Dehouck B, et al.
Conformationally restricted dipeptide amides as potent and selective neuronal nitric oxide synthase inhibitors.Other primary literatureUnknownActiveJournal of medicinal chemistry2006
Ji H, Gómez-Vidal JA, Martasek P, et al.
Spinal alpha(2)-adrenergic and muscarinic receptors and the NO release cascade mediate supraspinally produced effectiveness of gabapentin at decreasing mechanical hypersensitivity in mice after partial nerve injury.Other primary literatureAnimalActiveBritish journal of pharmacology2006
Takasu K, Honda M, Ono H, et al.
Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and development of pre-eclampsia: a case-control study and a meta-analysis.Other primary literatureUnknownActiveBMC pregnancy and childbirth2006
Yu CK, Casas JP, Savvidou MD, et al.
Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2006
Brahmachari S, Fung YK, Pahan K
Interaction between enteric epithelial cells and Peyer's patch lymphocytes in response to Shigella lipopolysaccharide: effect on nitric oxide and IL-6 release.Other primary literatureHuman & animalActiveWorld journal of gastroenterology2006
Chen J, Ng CP, Rowlands DK, et al.
Nitric oxide contributes to resistance of the Brown Norway rat to experimental autoimmune encephalomyelitis.Other primary literatureAnimalActiveThe American journal of pathology2005
Staykova MA, Paridaen JT, Cowden WB, et al.
Caveolin-1 gene knockout impairs nitrergic function in mouse small intestine.Other primary literatureAnimalActiveBritish journal of pharmacology2005
El-Yazbi AF, Cho WJ, Boddy G, et al.
Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin.Other primary literatureHuman & animalActiveBritish journal of pharmacology2005
Chiang YM, Lo CP, Chen YP, et al.
Human dendritic cell activity against Histoplasma capsulatum is mediated via phagolysosomal fusion.Other primary literatureHumanActiveInfection and immunity2005
Gildea LA, Ciraolo GM, Morris RE, et al.
Nitric oxide increases carbon monoxide production by piglet cerebral microvessels.Other primary literatureAnimalActiveAmerican journal of physiology. Heart and circulatory physiology2005
Leffler CW, Balabanova L, Fedinec AL, et al.
Nitric oxide and cGMP mediate alpha1D-adrenergic receptor-Stimulated protein secretion and p42/p44 MAPK activation in rat lacrimal gland.Other primary literatureAnimalActiveInvestigative ophthalmology & visual science2005
Hodges RR, Shatos MA, Tarko RS, et al.
Effect of bradykinin on nitric oxide production, urea synthesis and viability of rat hepatocyte cultures.Other primary literatureAnimalActiveBMC physiology2005
Sesti S, Martino G, Mazzulla S, et al.
Mechanisms of action of leptin in preventing gastric ulcer.Other primary literatureAnimalActiveWorld journal of gastroenterology2005
Adeyemi EO, Bastaki SA, Chandranath IS, et al.
Temporal expression of hepatic inducible nitric oxide synthase in liver cirrhosis.Other primary literatureAnimalActiveWorld journal of gastroenterology2005
Wei CL, Hon WM, Lee KH, et al.
The dual role of endothelial differentiation-related factor-1 in the cytosol and nucleus: modulation by protein kinase A.Other primary literatureHumanActiveCellular and molecular life sciences : CMLS2004
Ballabio E, Mariotti M, De Benedictis L, et al.
Nitric oxide-an endogenous inhibitor of gastric acid secretion in isolated human gastric glands.Other primary literatureHumanActiveBMC gastroenterology2004
Berg A, Redeen S, Ericson AC, et al.
Vascular endothelial cells promote acute plasticity in ependymoglial cells of the neuroendocrine brain.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2004
De Seranno S, Estrella C, Loyens A, et al.
Effects of nitric oxide on gastric ulceration induced by nicotine and cold-restraint stress.Other primary literatureAnimalActiveWorld journal of gastroenterology2004
Qui BS, Mei QB, Liu L, et al.
Arginase 1 overexpression in psoriasis: limitation of inducible nitric oxide synthase activity as a molecular mechanism for keratinocyte hyperproliferation.Other primary literatureHumanActiveThe American journal of pathology2003
Bruch-Gerharz D, Schnorr O, Suschek C, et al.
Hepatocyte growth factor activates endothelial nitric oxide synthase by Ca(2+)- and phosphoinositide 3-kinase/Akt-dependent phosphorylation in aortic endothelial cells.Other primary literatureHuman & animalActiveThe Biochemical journal2003
Makondo K, Kimura K, Kitamura N, et al.
Beta irradiation decreases collagen type II synthesis and increases nitric oxide production and cell death in articular chondrocytes.Other primary literatureAnimalActiveAnnals of the rheumatic diseases2003
Ailland J, Kampen WU, Schünke M, et al.
Arsenic-induced dysfunction in relaxation of blood vessels.Other primary literatureAnimalActiveEnvironmental health perspectives2003
Lee MY, Jung BI, Chung SM, et al.
Dual effect of nitric oxide in articular inflammatory pain in zymosan-induced arthritis in rats.Other primary literatureAnimalActiveBritish journal of pharmacology2002
da S Rocha JC, Peixoto ME, Jancar S, et al.
Nitric oxide inhibits the shedding of the glycosylphosphatidylinositol-anchored dipeptidase from porcine renal proximal tubules.Other primary literatureAnimalActiveThe Biochemical journal2002
Park SW, Yoon HJ, Lee HB, et al.
A new role for an old enzyme: nitrate reductase-mediated nitric oxide generation is required for abscisic acid-induced stomatal closure in Arabidopsis thaliana.Other primary literatureUnknownActiveProceedings of the National Academy of Sciences of the United States of America2002
Desikan R, Griffiths R, Hancock J, et al.
H(1)-Receptor activation triggers the endogenous nitric oxide signalling system in the rat submandibular gland.Other primary literatureAnimalActiveMediators of inflammation2002
Borda E, Stranieri G, Sterin-Borda L
Central role for interleukin-4 in regulating nitric oxide-mediated inhibition of T-cell proliferation and gamma interferon production in schistosomiasis.Other primary literatureAnimalActiveInfection and immunity2002
Patton EA, La Flamme AC, Pedras-Vasoncelos JA, et al.
High-Yield Method for Isolation and Culture of Endothelial Cells from Rat Coronary Blood Vessels Suitable for Analysis of Intracellular Calcium and Nitric Oxide Biosynthetic Pathways.Other primary literatureUnknownActiveBiological procedures online2002
Nistri S, Mazzetti L, Failli P, et al.
Critical time-window for NO-cGMP-dependent long-term memory formation after one-trial appetitive conditioning.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2002
Kemenes I, Kemenes G, Andrew RJ, et al.
Synaptic localization of nitric oxide synthase and soluble guanylyl cyclase in the hippocampus.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2002
Burette A, Zabel U, Weinberg RJ, et al.
Nitric oxide is necessary for multiple memory processes after learning that a food is inedible in aplysia.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2002
Katzoff A, Ben-Gedalya T, Susswein AJ
Mechanisms of beta-cell death in response to double-stranded (ds) RNA and interferon-gamma: dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosis.Other primary literatureAnimalActiveThe American journal of pathology2001
Scarim AL, Arnush M, Blair LA, et al.
Ginsenosides Rb1 and Re decrease cardiac contraction in adult rat ventricular myocytes: role of nitric oxide.Other primary literatureAnimalActiveBritish journal of pharmacology2001
Scott GI, Colligan PB, Ren BH, et al.
NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension.Other primary literatureAnimalExpression of concernProceedings of the National Academy of Sciences of the United States of America2001
Fiorucci S, Antonelli E, Morelli O, et al.
NMDA receptor and nitric oxide synthase activation regulate polysialylated neural cell adhesion molecule expression in adult brainstem synapses.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2001
Bouzioukh F, Tell F, Jean A, et al.
Early effects of exogenous arginine after the implantation of prosthetic material into the rat abdominal wall.Other primary literatureAnimalActiveLife sciences2000
Arbśs MA, Ferrando JM, Vidal J, et al.
NO contributes to proliferative suppression in a murine model of filariasis.Other primary literatureAnimalActiveInfection and immunity2000
O'Connor RA, Jenson JS, Devaney E
Interleukin-12 (IL-12) enhancement of the cellular immune response against human immunodeficiency virus type 1 env antigen in a DNA prime/vaccinia virus boost vaccine regimen is time and dose dependent: suppressive effects of IL-12 boost are mediated by nitric oxide.Other primary literatureHuman & animalActiveJournal of virology2000
Gherardi MM, Ramírez JC, Esteban M
Basal nitric oxide production is enhanced by hydraulic pressure in cultured human trabecular cells.Other primary literatureHumanActiveThe British journal of ophthalmology2000
Matsuo T
Exogenous nitric oxide inhibits apoptosis in guinea pig gastric mucous cells.Other primary literatureAnimalActiveGut2000
Potter CL, Hanson PJ
Feeding a protective hydrolysed casein diet to young diabetic-prone BB rats affects oxidation of L[U-14C]glutamine in islets and Peyer's patches, reduces abnormally high mitotic activity in mesenteric lymph nodes, enhances islet insulin and tends to normalize NO production.Other primary literatureAnimalActiveInternational journal of experimental diabetes research2000
Malaisse WJ, Olivares E, Laghmich A, et al.
Nitric oxide synthase inhibition by dimaprit and dimaprit analogues.Other primary literatureAnimalActiveBritish journal of pharmacology1999
Paquay JB, Hoen PA, Voss HP, et al.
beta-Endorphin blocks luteinizing hormone-releasing hormone release by inhibiting the nitricoxidergic pathway controlling its release.Other primary literatureAnimalActiveProceedings of the National Academy of Sciences of the United States of America1999
Faletti AG, Mastronardi CA, Lomniczi A, et al.
Mechanism of the intracellular killing and modulation of antibiotic susceptibility of Listeria monocytogenes in THP-1 macrophages activated by gamma interferon.Other primary literatureHumanActiveAntimicrobial agents and chemotherapy1999
Ouadrhiri Y, Scorneaux B, Sibille Y, et al.
Attenuated host resistance against Mycobacterium bovis BCG infection in mice lacking osteopontin.Other primary literatureAnimalActiveInfection and immunity1999
Nau GJ, Liaw L, Chupp GL, et al.
Leptin increases serotonin turnover by inhibition of brain nitric oxide synthesis.Other primary literatureAnimalActiveThe Journal of clinical investigation1999
Calapai G, Corica F, Corsonello A, et al.
Neuronal nitric oxide synthase mRNA upregulation in rat sensory neurons after spinal nerve ligation: lack of a role in allodynia development.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience1999
Luo ZD, Chaplan SR, Scott BP, et al.
Induction of nitric oxide synthase and microglial responses precede selective cell death induced by chronic impairment of oxidative metabolism.Other primary literatureAnimalActiveThe American journal of pathology1998
Calingasan NY, Park LC, Calo LL, et al.
Collagen deposition in a non-fibrotic lung granuloma model after nitric oxide inhibition.Other primary literatureAnimalActiveThe American journal of pathology1998
Hogaboam CM, Gallinat CS, Bone-Larson C, et al.
Vascular endothelial growth factor and nitric oxide synthase expression in human lung cancer and the relation to p53.Other primary literatureHumanActiveBritish journal of cancer1998
Ambs S, Bennett WP, Merriam WG, et al.
Role of nitric oxide in regulation of gastric acid secretion in rats: effects of NO donors and NO synthase inhibitor.Other primary literatureAnimalActiveBritish journal of pharmacology1998
Kato S, Kitamura M, Korolkiewicz RP, et al.
Inhibition of nitric oxide generation unmasks vascular dysfunction in insulin-resistant, obese JCR:LA-cp rats.Other primary literatureAnimalActiveBritish journal of pharmacology1998
McKendrick JD, Salas E, Dubé GP, et al.
Role of reactive oxygen species in the signalling cascade of cyclosporine A-mediated up-regulation of eNOS in vascular endothelial cells.Other primary literatureAnimalActiveBritish journal of pharmacology1998
López-Ongil S, Hernández-Perera O, Navarro-Antolín J, et al.
Nerve growth factor rapidly suppresses basal, NMDA-evoked, and AMPA-evoked nitric oxide synthase activity in rat hippocampus in vivo.Other primary literatureAnimalActiveProceedings of the National Academy of Sciences of the United States of America1998
Lam HH, Bhardwaj A, O'Connell MT, et al.
Effect of cytokines on growth of Toxoplasma gondii in murine astrocytes.Other primary literatureAnimalActiveInfection and immunity1998
Halonen SK, Chiu F, Weiss LM
Inducible nitric oxide synthase does not affect resolution of murine chlamydial genital tract infections or eradication of chlamydiae in primary murine cell culture.Other primary literatureAnimalActiveInfection and immunity1998
Ramsey KH, Miranpuri GS, Poulsen CE, et al.
Protective role of nitric oxide in Staphylococcus aureus infection in mice.Other primary literatureAnimalActiveInfection and immunity1998
Sasaki S, Miura T, Nishikawa S, et al.
On the protective mechanisms of nitric oxide in acute pancreatitis.Other primary literatureAnimalActiveGut1998
Werner J, Fernández-del Castillo C, Rivera JA, et al.
Pertussis toxin-sensitive G proteins influence nitric oxide synthase III activity and protein levels in rat heart.Other primary literatureAnimalActiveThe Journal of clinical investigation1998
Hare JM, Kim B, Flavahan NA, et al.
Effects of the 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors, atorvastatin and simvastatin, on the expression of endothelin-1 and endothelial nitric oxide synthase in vascular endothelial cells.Other primary literatureAnimalActiveThe Journal of clinical investigation1998
Hernández-Perera O, Pérez-Sala D, Navarro-Antolín J, et al.
Verotoxin and ricin have novel effects on preproendothelin-1 expression but fail to modify nitric oxide synthase (ecNOS) expression and NO production in vascular endothelium.Other primary literatureAnimalActiveThe Journal of clinical investigation1998
Bitzan MM, Wang Y, Lin J, et al.
Establishment of patterned thalamocortical connections does not require nitric oxide synthase.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience1998
Finney EM, Shatz CJ
Nitric oxide-producing islet cells modulate the release of sensory neuropeptides in the rat substantia gelatinosa.Other primary literatureAnimalActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience1998
Aimar P, Pasti L, Carmignoto G, et al.
Modulation of glutamine synthesis in cultured astrocytes by nitric oxide.Other primary literatureAnimalActiveCellular and molecular neurobiology1997
Miñana MD, Kosenko E, Marcaida G, et al.
Differential regulation of nitric oxide synthase mRNA expression by lipopolysaccharide and pro-inflammatory cytokines in fetal hepatocytes treated with cycloheximide.Other primary literatureAnimalActiveThe Biochemical journal1997
Casado M, Díaz-Guerra MJ, Boscá L, et al.
Effects of in vivo adventitial expression of recombinant endothelial nitric oxide synthase gene in cerebral arteries.Other primary literatureAnimalActiveProceedings of the National Academy of Sciences of the United States of America1997
Chen AF, Jiang SW, Crotty TB, et al.
Vascular estrogen receptors and endothelium-derived nitric oxide production in the mouse aorta. Gender difference and effect of estrogen receptor gene disruption.Other primary literatureAnimalActiveThe Journal of clinical investigation1997
Rubanyi GM, Freay AD, Kauser K, et al.
Kinetic modelling of the nitric oxide gradient generated in vitro by adherent cells expressing inducible nitric oxide synthase.Other primary literatureUnknownActiveThe Biochemical journal1996
Laurent M, Lepoivre M, Tenu JP
Iron chelates bind nitric oxide and decrease mortality in an experimental model of septic shock.Other primary literatureAnimalActiveProceedings of the National Academy of Sciences of the United States of America1996
Kazmierski WM, Wolberg G, Wilson JG, et al.
No .NO from NO synthase.Other primary literatureUnknownActiveProceedings of the National Academy of Sciences of the United States of America1996
Schmidt HH, Hofmann H, Schindler U, et al.
Characterization of nitric oxide synthase activity in sheep urinary tract: functional implications.Other primary literatureAnimalActiveBritish journal of pharmacology1996
García-Pascual A, Costa G, Labadia A, et al.
Rapid nitric oxide- and prostaglandin-dependent release of calcitonin gene-related peptide (CGRP) triggered by endotoxin in rat mesenteric arterial bed.Other primary literatureAnimalActiveBritish journal of pharmacology1996
Wang X, Wu Z, Tang Y, et al.
The effects of calcitonin gene-related peptide on tracheal smooth muscle of guinea-pigs in vitro.Other primary literatureAnimalActiveBritish journal of pharmacology1996
Ninomiya H, Uchida Y, Endo T, et al.
Nitric oxide induction by pertussis toxin in mouse spleen cells via gamma interferon.Other primary literatureAnimalActiveInfection and immunity1996
Sakurai S, Kamachi K, Konda T, et al.
Bile acid induced colonic irritation stimulates intracolonic nitric oxide release in humans.Other primary literatureHumanActiveGut1996
Casellas F, Mourelle M, Papo M, et al.
Nitric oxide inhibits viral replication in murine myocarditis.Other primary literatureAnimalActiveThe Journal of clinical investigation1996
Lowenstein CJ, Hill SL, Lafond-Walker A, et al.
In vivo targeting of inducible NO synthase with oligodeoxynucleotides protects rat kidney against ischemia.Other primary literatureAnimalActiveThe Journal of clinical investigation1996
Noiri E, Peresleni T, Miller F, et al.
Early embryo loss is associated with local production of nitric oxide by decidual mononuclear cells.Other primary literatureAnimalActiveThe Journal of experimental medicine1995
Haddad EK, Duclos AJ, Baines MG
The role of nitric oxide in cardiac depression induced by interleukin-1 beta and tumour necrosis factor-alpha.Other primary literatureAnimalActiveBritish journal of pharmacology1995
Schulz R, Panas DL, Catena R, et al.
Endogenous nitric oxide signalling system and the cardiac muscarinic acetylcholine receptor-inotropic response.Other primary literatureAnimalActiveBritish journal of pharmacology1995
Sterin-Borda L, Echagüe AV, Leiros CP, et al.
Purification and characterization of nitric oxide synthase (NOSNoc) from a Nocardia species.Other primary literatureUnknownActiveJournal of bacteriology1995
Chen Y, Rosazza JP
Enhanced colonic nitric oxide generation and nitric oxide synthase activity in ulcerative colitis and Crohn's disease.Other primary literatureHumanActiveGut1995
Rachmilewitz D, Stamler JS, Bachwich D, et al.
Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity.Other primary literatureAnimalActiveGut1995
Rachmilewitz D, Karmeli F, Okon E, et al.
The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor beta.Other primary literatureAnimalActiveThe Journal of clinical investigation1995
Pinsky DJ, Cai B, Yang X, et al.
Nitric oxide regulates the calcium current in isolated human atrial myocytes.Other primary literatureHuman & animalActiveThe Journal of clinical investigation1995
Kirstein M, Rivet-Bastide M, Hatem S, et al.
Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels.Other primary literatureAnimalActiveThe Journal of clinical investigation1995
Genaro AM, Hortelano S, Alvarez A, et al.
Autocrine inhibition of Na+/K(+)-ATPase by nitric oxide in mouse proximal tubule epithelial cells.Other primary literatureAnimalActiveThe Journal of clinical investigation1995
Guzman NJ, Fang MZ, Tang SS, et al.
Thaliporphine selectively inhibits expression of the inducible, but not the constitutive, nitric oxide synthase.Other primary literatureAnimalActiveThe Biochemical journal1994
Yu SM
Pteridine biosynthesis and nitric oxide synthase in Physarum polycephalum.Other primary literatureAnimalActiveThe Biochemical journal1994
Werner-Felmayer G, Golderer G, Werner ER, et al.
Formation of free nitric oxide from l-arginine by nitric oxide synthase: direct enhancement of generation by superoxide dismutase.Other primary literatureUnknownActiveProceedings of the National Academy of Sciences of the United States of America1994
Hobbs AJ, Fukuto JM, Ignarro LJ
Nitric oxide: a mediator in rat tubular hypoxia/reoxygenation injury.Other primary literatureAnimalActiveProceedings of the National Academy of Sciences of the United States of America1994
Yu L, Gengaro PE, Niederberger M, et al.
Induction of nitric oxide synthase protects against malaria in mice exposed to irradiated Plasmodium berghei infected mosquitoes: involvement of interferon gamma and CD8+ T cells.Other primary literatureAnimalActiveThe Journal of experimental medicine1994
Seguin MC, Klotz FW, Schneider I, et al.
The protective role of endogenously synthesized nitric oxide in staphylococcal enterotoxin B-induced shock in mice.Other primary literatureAnimalActiveThe Journal of experimental medicine1994
Florquin S, Amraoui Z, Dubois C, et al.
Isolation of a nitric oxide inhibitor from mammary tumor cells and its characterization as phosphatidyl serine.Other primary literatureAnimalActiveThe Journal of experimental medicine1994
Calderón C, Huang ZH, Gage DA, et al.
Nitric oxide opens ATP-sensitive K+ channels through suppression of phosphofructokinase activity and inhibits glucose-induced insulin release in pancreatic beta cells.Other primary literatureAnimalActiveThe Journal of general physiology1994
Tsuura Y, Ishida H, Hayashi S, et al.
Induction of nitric oxide synthase in cultured vascular smooth muscle cells: the role of cyclic AMP.Other primary literatureAnimalActiveBritish journal of pharmacology1994
Hirokawa K, O'Shaughnessy K, Moore K, et al.
Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice.Other primary literatureAnimalActiveThe Journal of clinical investigation1994
Cross AH, Misko TP, Lin RF, et al.
Induction of myocardial nitric oxide synthase by cardiac allograft rejection.Other primary literatureAnimalActiveThe Journal of clinical investigation1994
Yang X, Chowdhury N, Cai B, et al.
Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine.Other primary literatureHuman & animalActiveProceedings of the National Academy of Sciences of the United States of America1993
Ignarro LJ, Fukuto JM, Griscavage JM, et al.
Porcine ventricular endocardial cells in culture express the inducible form of nitric oxide synthase.Other primary literatureAnimalActiveBritish journal of pharmacology1993
Smith JA, Radomski MW, Schulz R, et al.
Oxygen tension regulates the nitric oxide pathway. Physiological role in penile erection.Other primary literatureHuman & animalActiveThe Journal of clinical investigation1993
Kim N, Vardi Y, Padma-Nathan H, et al.
Cytokine-induced expression of a nitric oxide synthase in rat renal tubule cells.Other primary literatureHuman & animalActiveThe Journal of clinical investigation1993
Markewitz BA, Michael JR, Kohan DE
NO accounts completely for the oxygenated nitrogen species generated by enzymic L-arginine oxygenation.Other primary literatureAnimalActiveThe Biochemical journal1992
Mülsch A, Vanin A, Mordvintcev P, et al.
Induction and potential biological relevance of a Ca(2+)-independent nitric oxide synthase in the myocardium.Other primary literatureAnimalActiveBritish journal of pharmacology1992
Schulz R, Nava E, Moncada S
Activation of macrophages for destruction of Francisella tularensis: identification of cytokines, effector cells, and effector molecules.Other primary literatureAnimalActiveInfection and immunity1992
Fortier AH, Polsinelli T, Green SJ, et al.
Effects of interferon-gamma on nitric oxide synthase activity and endothelin-1 production by vascular endothelial cells.Other primary literatureAnimalActiveThe Journal of clinical investigation1992
Lamas S, Michel T, Collins T, et al.
Tetrahydrobiopterin, a cofactor for rat cerebellar nitric oxide synthase, does not function as a reactant in the oxygenation of arginine.Other primary literatureAnimalActiveProceedings of the National Academy of Sciences of the United States of America1991
Giovanelli J, Campos KL, Kaufman S
Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide.Other primary literatureAnimalActiveThe Journal of experimental medicine1991
Kwon NS, Stuehr DJ, Nathan CF
Nitric oxide synthase in cultured endocardial cells of the pig.Other primary literatureAnimalActiveBritish journal of pharmacology1991
Schulz R, Smith JA, Lewis MJ, et al.
Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.Other primary literatureAnimalActiveProceedings of the National Academy of Sciences of the United States of America1989
Knowles RG, Palacios M, Palmer RM, et al.