Structure-Property Relationships in Fluorine-Free Ionic Liquids and Salts Utilising the Acesulfame Anion.Other primary literatureUnknownActiveChemSusChem2026
Mah WH, Forsyth CM, O'Dell LA, et al.
Mogroside-Rich Monk Fruit Extract Improves Glycemic Control Without Promoting Additional Weight Gain Compared With Sucralose and Sucrose in High-Fat Diet-Induced Obese Mice.Other primary literatureUnknownActiveFood science & nutrition2026
Man JWK, Huang YC, Hsieh RH, et al.
Coordination-driven high sucralose loading, releasing and purifying performance of edible β-cyclodextrin metal-organic frameworks.Other primary literatureUnknownActiveJournal of the science of food and agriculture2026
Jie H, Zeng W, Lv Z, et al.
Chronic Aspartame Exposure Leading to Hypertension in Mice may be Related to the Activation of the Wnt/β-Catenin Signaling Pathway in the Hypothalamus.Other primary literatureAnimalActiveMolecular nutrition & food research2026
Yang W, Li Q, Tong T, et al.
Aspartame Peptide-Based Piezoelectric Supramolecular Material Toward Energy Harvesting.Other primary literatureUnknownActiveSmall (Weinheim an der Bergstrasse, Germany)2026
Yang B, Zhang Y, Liu S, et al.
A sucralose-based sweetener promotes biofilm formation and plasmid-mediated antibiotic resistance transfer in opportunistic gut bacteria.Other primary literatureUnknownActiveArchives of microbiology2026
Biswas A, Rahman MH, Chichger H, et al.
Integrated network toxicology and experimental validation to investigate potential mechanisms associated with aspartame-induced malignant phenotypic changes in colorectal cancer.Other primary literatureUnknownActiveNaunyn-Schmiedeberg's archives of pharmacology2026
Liu Q, Yu D, Qiao L, et al.
Environmentally-relevant concentrations of dissolved sucralose affect gas exchange, chlorophyll content, and flowering hue of three North American prairie species.Other primary literatureUnknownActiveEcotoxicology (London, England)2026
Costello M, Budny ML, Lemoine NP
Molecular mechanism of aspartame recognition by the human sweet taste receptor T1R2-T1R3 revealed by homology modeling and molecular dynamics simulations.Other primary literatureHumanActiveJournal of computer-aided molecular design2026
Tong M, Duan S, Wang L, et al.
Aspartame drives the continuous progression from MASLD to HCC.Other primary literatureUnknownActiveDiscover oncology2026
Zhang X, Tan R, Ma Y, et al.
Exposing Zn(002) Texture with Sucralose Additive for Stable and Dendrite-Free Aqueous Zinc-Ion Batteries.Other primary literatureUnknownActiveNano-micro letters2026
Tao F, Ren Y, Mo L, et al.
Aspartame decreases fat deposits in mice at a cost of mild cardiac hypertrophy and reduced cognitive performance.Other primary literatureAnimalActiveBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2026
Aiestaran-Zelaia I, Sánchez-Guisado MJ, Beraza M, et al.
Investigation of the healing effects of phenylboronic acid and exosome on the TGF-β-Smad/REDD1 pathway in aspartame-induced liver damage in BALB/c type mice.Other primary literatureUnknownActiveBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2026
Sahin B, Acar TY, Kurt A, et al.
From sweetener to risk factor: Network toxicology, molecular docking and molecular dynamics reveal the mechanism of aspartame in promoting coronary heart disease.Other primary literatureHumanActiveChemico-biological interactions2026
Xia M, Liu X, Wang K, et al.
A comprehensive analysis reveals the potential risks and molecular connections between aspartame and polycystic ovary syndrome.Other primary literatureUnknownActiveComputational biology and chemistry2026
Huang Z, Xie L, Zheng X, et al.
Computational network toxicology of non-nutritive sweeteners in ulcerative colitis: From Aspartame-MMP9 interaction to mechanism-guided intervention.Other primary literatureHumanActiveComputers in biology and medicine2026
Feng Y, Huang S, Huang Z, et al.
Aspartame exacerbates cerebral ischemia-reperfusion injury via mitochondrial dysfunction and ERK/CREB1 pathway suppression.Other primary literatureAnimalActiveEcotoxicology and environmental safety2026
Bai Y, Feng J, Wu XY, et al.
Aspartame exposure promotes endometriosis progression through PTGS2-mediated oxidative stress and mitochondrial dysfunction.Other primary literatureHuman & animalActiveEcotoxicology and environmental safety2026
Li J, Hu X, Guo C, et al.
Bitter truth about artificial sweeteners: A critical review on the ecotoxicity of sucralose, acesulfame, saccharin and cyclamate.ReviewAnimalActiveEnvironmental pollution (Barking, Essex : 1987)2026
Loll A, Eilebrecht E, Schäfers C, et al.
Artificial sweetener acesulfame induces oxidative stress, neurotoxicity, and glycolipid metabolic disruption in zebrafish (Daniorerio).Other primary literatureAnimalActiveEnvironmental pollution (Barking, Essex : 1987)2026
Liu X, Wang Q, Lv H, et al.
Aspartame promotes ovarian cancer progression: A multi-omics study integrating mendelian randomization, network toxicology, and in vitro validation.Other primary literatureHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2026
Gong Q, Liang D, Luo Y, et al.
Co-exposure to benzoic acid and acesulfame K synergistically induces nephrotoxicity through the CTNNB1/STAT3 axis.Other primary literatureHuman & animalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2026
Ma Y, Mai X, Fan W, et al.
Maternal rebaudioside A and acesulfame-K exposure reprograms offspring submandibular gland development in a sex-dependent manner.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2026
Saiz-Gonzalo G, Drouin G, Rao Y, et al.
Beyond sweetness: A review of the health and safety of acesulfame-K.ReviewHuman & animalActiveFood chemistry2026
Chowdhury CR, Havlik J
Smartphone-based digital imaging for rapid and green quantification of aspartame in lemon-flavored soft drinks.Other primary literatureUnknownActiveFood chemistry2026
de Souza Gomes BR, Dos Santos IR, Santos JM
Aspartame enhances innate immunity and extends lifespan in Caenorhabditis elegans via autophagy pathway.Other primary literatureAnimalActiveFood research international (Ottawa, Ont.)2026
Han C, Luo J, Ding L, et al.
Retro-nasal perception of sucralose aerosols in model wine systems.Other primary literatureHumanActiveFood research international (Ottawa, Ont.)2026
Chen L, Liu G, Su W, et al.
Sucralose promotes cardiac redox-metabolic remodeling through MRPL12-associated mitoribosomal stress.Other primary literatureUnknownActiveFree radical biology & medicine2026
Sun Y, Zhai H, Wang J, et al.
High sucralose exposure in early pregnancy increases the susceptibility of heart defects in mice offspring.Other primary literatureUnknownActiveiScience2026
Zhang Z, Yu Z, Shi H, et al.
Aerobic biodegradation of acesulfame by sediment-enriched microbial consortia: Kinetics, pathway, and microbial mechanism.Other primary literatureUnknownActiveJournal of environmental management2026
Zhang X, Chen J, Li Y, et al.
Aspartame promotes intestinal tumor progression via Akkermansia muciniphila -mediated 5-hydroxytryptophan production.Other primary literatureAnimalActiveJournal of hazardous materials2026
Zhu Y, Zhu J, Hu Z, et al.
Iron ores with contrasting redox properties drive iron biogeochemical cycling to enhance acesulfame and nutrients removal in constructed wetlands.Other primary literatureUnknownActiveJournal of hazardous materials2026
Li M, Lin Z, Yan P, et al.
Erythritol, sucrose, and sucralose elicit similar reward responses after flavor preference learning in healthy humans.Randomized controlled trialHumanActivePhysiology & behavior2026
Flad E, Teysseire F, Budzinska A, et al.
Nanoencapsulation modulates aspartame metabolite exposure: Toxicokinetic, mechanistic, and pharmacological evaluation in a glucocorticoid dysfunction model.Other primary literatureAnimalActiveToxicology and applied pharmacology2026
Fawzy SF, Newairy AA, Ghareeb DA, et al.
Association between Aspartame Consumption and Cancer Risk: Evidence from a Large Prospective Cohort.Other primary literatureHumanActiveThe Journal of nutrition2026
Zhu X, Welsh JA, McCullough ML, et al.
Aspartame and Obesity: A Comprehensive Review of Mechanisms of Action, Transgenerational Effects, and Health Implications.ReviewUnknownActiveThe Journal of nutrition2026
Liu L, Yan R
Crosstalk with Chlorella sp. reshapes the environmental fates of aspartame: From stress responses to contaminant destabilization.Other primary literatureUnknownActiveWater research2026
Zhang L, Ruan R, Liu Y, et al.
Microbial cleavage and mineralization of acesulfame by Shinella sp. strain KJ01.Other primary literatureUnknownActiveWater research2026
Yang P, Liu H, Xu J, et al.
Sucralose and PMMA Microplastics Synergistically Induce Obesity with Altered Locomotion and Metabolism in <i>Caenorhabditis elegans</i>.Other primary literatureAnimalActiveEnvironmental science & technology2026
Liang Y, Liu Y, Cao X, et al.
Human Gut Microbiome Can Degrade the Sweetener Acesulfame K with Potential Damaging Effects in the Intestinal Barrier Function.Other primary literatureHumanActiveJournal of agricultural and food chemistry2026
Bellanco A, Yépez-Notario C, Lozano M, et al.
No indication of histological changes in embryonic somatosensory cortex development upon maternal aspartame consumption in mice.Other primary literatureUnknownActiveNPJ science of food2026
Andriichuk L, Namba T
Long-term sucralose exposure accelerates ovarian aging via gut microbiota dysbiosis.Other primary literatureUnknownActiveNPJ science of food2026
Chen J, Zhang D, Gao J, et al.
In silico exploration of potential associations between aspartame and cardiometabolic disease networks: a network toxicology study.Other primary literatureUnknownActiveScientific reports2026
Lin C, Lin X, Wang C, et al.
Transcriptomic evidence of hypothalamic neuroinflammation in mice due to aspartame exposure through the TLR4/NF-κB/NLRP3 pathway.Other primary literatureAnimalActiveFood & function2026
Yang W, Tong T, Li Q, et al.
Sucralose is accumulated in adipose tissue and plasma but minimally impacts inflammation in lean and obese mice.Other primary literatureUnknownActiveFood & function2026
Pallot F, Lachaise I, Astier J, et al.
Neurotoxic and metabolic effects of chronic aspartame consumption in rodent models: a systematic review and meta-analysis.ReviewUnknownActiveToxicology mechanisms and methods2026
Choudhary AK, Singh N
Aspartame and Its Potential Neurocognitive Effects in Humans.ReviewHuman & animalActiveNutrition reviews2026
Fogel MN, Khalil A, Khaled SF, et al.
Uncovering the potential mechanisms of aspartame-induced oral leukoplakia via integrated network toxicology and molecular dynamics simulations.Other primary literatureUnknownActiveInternational journal of surgery (London, England)2026
Shen Y, You Z, Xie S, et al.
Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame.Other primary literatureHumanActiveAllergy2026
Pat Y, Yazici D, Zeyneloglu C, et al.
Sucralose Exposure During Pregnancy Elevates Gestational Diabetes Risk via Gut Microbiota-Metabolic Axis in Mice.Other primary literatureAnimalActiveJournal of diabetes research2026
Song J, He J, Liang Z
The Safety Profile of Aspartame: A Review of Regulatory Standards and Emerging Health Concerns.ReviewUnknownActiveJournal of nutrition and metabolism2026
Öncel HU, Sökmen Z
High-Dose Sucralose Is Associated With Lacrimal Circadian Remodeling, Reduced Immunometabolic Signatures, and Reduced Tear Secretion.Other primary literatureAnimalActiveInvestigative ophthalmology & visual science2026
Qi D, Yang T, Pei X, et al.
The Effects of Aspartame, Sucrose, and Water on Short-Term Cognitive Performance.Other primary literatureUnknownActivePerceptual and motor skills2026
Jacobson MM, Passey JK, Allen SP, et al.
Long-term aspartame consumption affects global levels of DNA methylation in different types of rat tissues.Other primary literatureUnknownActiveNutrition and health2026
Sadic AK, Susgun S, Alkhalidi D, et al.
Effect of Sucralose on Cardiometabolic Health: A Review on Possible Mechanisms.ReviewHuman & animalActiveMetabolic syndrome and related disorders2026
Ni D, Parihar A, Sen S
Sucralose as a Way to Enhance Regulatory T Cells, the SWEET Trial: Clinical Research Protocol.Other primary literatureUnknownActiveCanadian journal of kidney health and disease2026
Bourguignon L, Benazzouk Y, Bokou-Gianneli E, et al.
Aspartame and asthma: immunomodulatory effects on airway inflammation.Other primary literatureUnknownActiveRespiratory research2026
Utami FA, Huang SY, Liu YH, et al.
Sucralose inhibited cell survival through the activation of ER stress in human endothelial progenitor cells.Other primary literatureHumanActivePloS one2026
Li CY, Lin HY, Chiang EI, et al.
Aspartame and Neurotoxicity: Quantitative Insights from Biomarker and Dose-response Analysis.Meta-analysisHuman & animalActiveCurrent neurovascular research2026
Choudhary AK, Singh N
Effects of Allulose vs Aspartame Consumption on Postprandial Glucagon-Like Peptide-1 Profiles and Metabolic Health: Protocol for a Randomized, Crossover, Double-Blind, Placebo-Controlled Trial.Other primary literatureHumanActiveJMIR research protocols2026
Busch S, Ferrario PG, Henk AK, et al.
Artificial sweeteners and their implications for patients with diabetes: a systematic review and meta-analysis.Meta-analysisHumanActiveJournal of medicine and life2026
Lück A, Standl F, Stich H
Re-evaluation of sucralose (E 955) as a food additive and evaluation of a new application on extension of use of sucralose (E 955) in fine bakery wares.Other primary literatureUnknownActiveEFSA journal. European Food Safety Authority2026
Castle L, Andreassen M, Aquilina G, et al.
Aspartame may promote erectile dysfunction via DPP4-mediated endothelial dysfunction and apoptosis: evidence from network toxicology, molecular dynamics simulation, and experimental validation.Other primary literatureUnknownActiveFrontiers in nutrition2026
Dai Z, Wang S, Chen Z, et al.
Sucralose and the Gut-Immune Axis: Emerging Evidence Linking Dysbiosis, Barrier Alterations, and Implications for Colitis and Colorectal Cancer Immunotherapy.ReviewUnknownActiveBiomedicines2026
Mejía-Muñoz A, Cedillo Monter J, Saldívar-Cerón HI, et al.
Structural and Energetic Determinants of Sweet Protein Recognition: Mechanistic Insights into Thaumatin Binding to the Human T1R2/T1R3 Receptor.Other primary literatureHumanActiveInternational journal of molecular sciences2026
Kiewhuo K, Basharat G, Rungrotmongkol T, et al.
Mutual Influence of Sucralose and Bisphenol A on Biological and Neurobehavioral Action in <i>Drosophila melanogaster</i>.Other primary literatureAnimalActiveInternational journal of molecular sciences2026
Miranda N, Tkach V, Ferreira J, et al.
Integrative Network Toxicology, Machine Learning, Single-Cell Analysis, scTenifoldKnk-Based Virtual Knockout, and Molecular Docking Suggest a Potential Molecular Link Between Aspartame and Rheumatoid Arthritis Involving <i>HLA-DRB1</i>.Other primary literatureHumanActiveInternational journal of molecular sciences2026
Yan T, He Q, Shi X
Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend.Other primary literatureHuman & animalCorrectedInternational journal of molecular medicine2026
Lin PY, Xie JR, Qian TC, et al.
Health Effects of Sugar-Sweetened and Artificially Sweetened Beverages: Umbrella Review and Evidence-Based Consensus Statement of the Korean Diabetes Association and the Korean Nutrition Society.Systematic reviewHumanActiveDiabetes & metabolism journal2026
Choi JH, Song S, Kim SK, et al.
Retro-nasal perception of sucralose aerosols in model wine systemsOther primary literatureUnknownUnknownFood Research International.2026
Chen L, Liu G, Su W, et al.
Extraction of acesulfame potassium from sweetened foods using a K₃PO₄-PEG aqueous two-phase systemOther primary literatureUnknownUnknownJournal of food composition and analysis : an official publication of the United Nations University, International Network of Food Data Systems2026
Zhang X, Cai Z, Zong W
Aspartame enhances innate immunity and extends lifespan in Caenorhabditis elegans via autophagy pathwayOther primary literatureUnknownUnknownFood Research International.2026
Han C, Luo J, Ding L, et al.
Menthol-like cooling compounds, including (R)-(-)-carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K.Other primary literatureHumanActiveFEBS open bio2025
Saito M, Misaka T
Developing Sugar-Free Chewing Gum With Stevia as an Aspartame Alternative.Other primary literatureUnknownActiveFood science & nutrition2025
Aykut A, Kirkin C
Investigating the Impact of Aspartame on Ulcerative Colitis Through Network Toxicology and Molecular Docking.Other primary literatureUnknownActiveFood science & nutrition2025
Ge L, Ma L, Jin Z
Assessing the temporal profile and liking of sugar-free spicy dark chocolates with different concentrations of Capsicum baccatum pepper and rebaudioside A.Other primary literatureHumanActiveJournal of the science of food and agriculture2025
Martins GAR, Augusto PPC, Luccas V, et al.
Stick-Core-Shell Magnetic Dummy Molecularly Imprinted Polymers for the Determination of Aspartame in Food Sample.Other primary literatureUnknownActiveJournal of separation science2025
Yao B, Huang L, Li C, et al.
Sesame oil ameliorates aspartame-induced immunotoxicity in mice: a hematological, antioxidative, and histopathological evaluation.Other primary literatureAnimalActiveJournal of molecular histology2025
Basalat K, Fahad AUM, Zahid A, et al.
The Antioxidative, Anti-inflammatory and Anti-apoptotic Effects of Tetrapleura Tetraptera (Aidan) Ethanol Leaf Extract in the Brain of Wistar Rats Exposed to Aspartame.Other primary literatureAnimalActiveMolecular neurobiology2025
Lawal AO, Agboola OO, Akinjiyan MO, et al.
Sweet or sour? A review of the Aspartame market landscape, carcinogenicity, and its socioeconomic impact.ReviewUnknownActiveJournal of food science and technology2025
Sharma H, Hilal A, Aseri GK, et al.
Aspartame Endowed ZnO-Based Self-Healing Solid Electrolyte Interface Film for Long-Cycling and Wide-Temperature Aqueous Zn-Ion Batteries.Other primary literatureUnknownActiveNano-micro letters2025
Shi Y, Liu Y, Chang R, et al.
The Effects of Aspartame on Glucose, Insulin, and Appetite-Regulating Hormone Responses in Humans: Systematic Review and Meta-Analyses.Meta-analysisHumanActiveAdvances in nutrition (Bethesda, Md.)2025
Boxall LR, Eskandari F, Wallis J, et al.
Toxicology of aspartame to largemouth bass (Micropterus salmoides) on the basis of antioxidant capacity, liver histology and the intestinal microbiotaOther primary literatureUnknownUnknownAnimal feed science and technology2025
Su Q, Yang J, Yang Z, et al.
Effect of Replacing Added Sugars with Sucralose on Gut Microbiome Composition Among Asian Indian Adults in Two 12-week Randomized Controlled Trials.Other primary literatureUnknownActiveCurrent developments in nutrition2025
Haslam DE, Abirami K, Starr JR, et al.
Comprehensive analysis of complicated chlorination products in sucralose production: Separation, purification, structural identification, quantification and source tracing.Other primary literatureUnknownActiveJournal of chromatography. A2025
Chen X, Lin H, Lin X, et al.
Sucralose consumption modifies glucose homeostasis, gut microbiota, Curli protein, and related metabolites in healthy individuals: A randomized placebo-controlled, triple-blind trial.Randomized controlled trialHumanActiveClinical nutrition ESPEN2025
Romo-Romo A, Sánchez-Tapia M, López-Carrasco MG, et al.
Sweetener aspartame aggravates atherosclerosis through insulin-triggered inflammation.Other primary literatureHuman & animalActiveCell metabolism2025
Wu W, Sui W, Chen S, et al.
Does sweet turn sour? How aspartame aggravates atherosclerosis in a preclinical model.Other primary literatureHuman & animalActiveCell metabolism2025
Pepino MY, Amengual J
Association of sucralose consumption with insulin response and sensitivity.ReviewHumanActiveDiabetes & metabolic syndrome2025
Kodumayil S, Gebril A, Nair S, et al.
Aspartame increases the risk of liver cancer through CASP1 protein: A comprehensive network analysis insights.Other primary literatureHumanActiveEcotoxicology and environmental safety2025
Li NR, Zeng YX, Gu YF, et al.
Influence of artificial sweeteners sodium saccharin and acesulfame potassium on the hydration properties, taste behavior and solubility of caffeine.Other primary literatureHumanActiveFood chemistry2025
Vukov A, Borović TT, Vraneš M
Research on the effects of different sugar substitutes-Mogroside V, Stevioside, Sucralose, and Erythritol-On glucose, lipid, and protein metabolism in type 2 diabetic mice.Other primary literatureAnimalActiveFood research international (Ottawa, Ont.)2025
Huang H, Wang B, Peng Z, et al.
Rapid detection of aspartame in beverages using a molecularly imprinted polymer-based fluorescence sensor.Other primary literatureUnknownActiveFood research international (Ottawa, Ont.)2025
Jia H, Xiong S, Yu X, et al.
Evaluation of the effect of sodium alginate, hydroxyethyl cellulose, aspartame, and poly(ethylene oxide)-b-poly(propylene oxide) copolymer on the in-vitro corrosion of AZ31 Mg alloy in simulated body fluid.Other primary literatureUnknownActiveInternational journal of biological macromolecules2025
Aleid AA, Solomon MM, Umoren PS, et al.
Maternal aspartame exposure alters lung Th1/Th2 cytokine balance in offspring through nuclear factor-κB activation.Other primary literatureAnimalActiveInternational immunopharmacology2025
Chuang HC, Yang YSH, Chou HC, et al.
The non-cariogenic effects of aspartame: A systematic review and meta-analysis.Meta-analysisHuman & animalActiveJournal of dentistry2025
Fleming SA, Fleming RAF, Peregoy J
The effect of allulose, sucralose, and xylitol on <i>Streptococcus mutans</i> acid production.Other primary literatureUnknownActiveJADA foundational science2025
Ruby JD, Momeni SS, Wu H
Aspartame affects methane yield and enhances transmission of antibiotic resistance genes during anaerobic digestion of sludge.Other primary literatureUnknownActiveJournal of hazardous materials2025
Xu J, Xiang Y, Yang Z, et al.
Comparative study on the degradation of sucralose by UV/persulfate and UV/periodate processes: Performance, dechlorination, and technical feasibility.Other primary literatureUnknownActiveJournal of hazardous materials2025
Yue J, Guo W, Liang S, et al.
Acesulfame degradation within a methane-fed biofilm: a novel and efficient biodegradation route.Other primary literatureUnknownActiveJournal of hazardous materials2025
Lu W, Sun S, Wang Q, et al.
Aspartame consumption linked to delayed puberty and mitochondrial Dysfunction: Evidence from human and animal studies.Other primary literatureHuman & animalActiveThe Journal of nutritional biochemistry2025
Chen YC, Wang ZL, Lin YF, et al.
Sucralose uses reward pathways to promote acute caloric intake.Other primary literatureAnimalActiveNeuropeptides2025
Wang QP, Li AQ, Wang B, et al.
Network toxicology and mechanistic insights reveal the oxytocin receptor (OXTR) as a key mediator of aspartame-associated atrial remodeling.Other primary literatureHuman & animalActiveToxicology and applied pharmacology2025
Kong Y, Li S, Wang C, et al.
Aspartame subacute exposure does not affect immune system of BALB/c mice following a tiered approach.Other primary literatureAnimalActiveTissue & cell2025
Farahi SMM, Forouzanfar F, Memar B, et al.
Evaluating the role of glutathione reductase in aspartame-induced liver hepatocellular carcinoma: A molecular network and prognostic approach.Other primary literatureHumanActiveToxicology letters2025
Sun W, Huo S, Li S, et al.
Simultaneous Elucidation of the Chemodiversity of Dissolved Organic Matter and Quantitation of Trace Organic Contaminant Sucralose by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.Other primary literatureUnknownActiveAnalytical chemistry2025
You Q, Cheng Y, Fu QL, et al.
Molecular Crosstalk between Artificial Sweetener Aspartame and Diabetes-Linked Insulin Hormone Unveils Possible Amyloidosis Risks.Other primary literatureHumanActiveBiomacromolecules2025
Ansari M, Prajapati KP, Mittal S, et al.
Effect of Sucrose and Sucralose on the Gelation of Gelatin.Other primary literatureUnknownActiveBiomacromolecules2025
Maki Y, Matsuo K, Annaka M
First Crystal Structure of an Aspartame Cocrystal.Other primary literatureUnknownActiveCrystal growth & design2025
Fereidouni N, Aljohani M, Erxleben A
Acesulfame Potassium Alleviates Food Allergy via Mast Cell Stabilization and MAPK-Mediated Immune Regulation.Other primary literatureHuman & animalActiveJournal of agricultural and food chemistry2025
Xu Z, Yan L, Yang Z, et al.
Maternal Aspartame Exposure Induces Neonatal Pulmonary Metabolic Dysregulation and Redox Imbalance: A Multiomics Investigation of Gut Microbiota-Host Interactions.Other primary literatureHuman & animalActiveJournal of agricultural and food chemistry2025
Ho SY, Lee CY, Chou HC, et al.
Dietary Sucralose Exacerbates Ovalbumin-Induced Food Allergy via Dendritic Cells Modulation: In Vitro and In Vivo Studies.Other primary literatureHuman & animalActiveJournal of agricultural and food chemistry2025
Yan L, Xu Z, Madjirebaye P, et al.
Decreased Crystal Plasticity by Solvation - the Case of Levofloxacin Acesulfame.Other primary literatureUnknownActiveMolecular pharmaceutics2025
Huang PS, Sun CC
The Non-Negligible Effect of Activating Zn on a Bimetallic Carbon for the Degradation of Acesulfame.Other primary literatureUnknownActiveACS applied materials & interfaces2025
Yang X, Shen H, Chen H, et al.
Aspartame exposures in the US population: Demonstration of a novel approach for exposure estimates to food additives using NHANES data.Other primary literatureHumanActiveJournal of exposure science & environmental epidemiology2025
Riess LE, Huynh BQ, Nachman KE
Genome-wide association study of the taste and hedonic ratings of the low-calorie sweetener acesulfame potassium.Observational studyHumanActiveScientific reports2025
Kan M, Saraiva LR, Hwang LD, et al.
Aspartame and ischemic stroke: unraveling the molecular link through network toxicology and molecular docking analysis.Other primary literatureHumanActiveScientific reports2025
Zhang T, Wang T, Yu K, et al.
Analysis of toxicity and mechanisms of aspartame in kidney stones with network toxicology and molecular docking strategy.Other primary literatureHumanActiveScientific reports2025
Xu K, Zhang Q, Shen Z, et al.
Receptor mechanism producing a sweet taste from plant aroma compounds.Other primary literatureHuman & animalActiveScientific reports2025
Horie F, Sanematsu K, Yasumatsu K, et al.
Comparative effects of different sugar substitutes: Mogroside V, stevioside, sucralose, and erythritol on intestinal health in a type 2 diabetes mellitus mouse.Other primary literatureAnimalActiveFood & function2025
Huang H, Liu S, Peng Z, et al.
Viscoelastic behavior of wormlike micellar solutions formed by an aspartame-based bicephalous anionic surfactant.Other primary literatureUnknownActiveSoft matter2025
Qiu B, Chen Z, Pei X, et al.
Human brain responses to the artificial sweetener sucralose and sucrose in the presence of flavour modifier.Other primary literatureHumanActiveNutritional neuroscience2025
Ko HK, Shi J, Eidenberger T, et al.
Consumption of aspartame and risk of breast cancer in the Nurses' Health Studies.Other primary literatureHumanActiveJournal of the National Cancer Institute2025
Romanos-Nanclares A, Schernhammer E, Willett WC, et al.
ANPEP as a potential mediator linking aspartame exposure to MAFLD: insights from network toxicology and multi-omics analyses.Other primary literatureUnknownActiveInternational journal of surgery (London, England)2025
Xu L, Zhang C, Xin S, et al.
Investigation of the toxic mechanism of aspartame on female infertility using network toxicology and molecular docking approaches.Other primary literatureHumanActiveMedicine2025
Yang T, Gao X, Pang X, et al.
Aspartame and cardiovascular disease: Unraveling potential molecular mechanisms through integrative network toxicology, molecular docking, and dynamics simulation.Other primary literatureHumanActiveMedicine2025
Yang T, Luo J, Zhang L, et al.
No Evidence of Metabolomic Disruptions From Real-World Intakes of Aspartame or Saccharin: The Coronary Artery Risk Development in Young Adults Study.Other primary literatureHumanActiveJournal of diabetes2025
Steffen BT, Lusczek ER, Jacobs DR Jr, et al.
Sucralose Consumption Ablates Cancer Immunotherapy Response through Microbiome Disruption.Other primary literatureHuman & animalActiveCancer discovery2025
Morder KM, Nguyen M, Wilfahrt DN, et al.
A large language model-based tool for identifying relationships to industry in research on the carcinogenicity of benzene, cobalt, and aspartame.Other primary literatureHuman & animalActiveEnvironmental health : a global access science source2025
DeBono NL, Amar V, Hardy H, et al.
Exposure to Sucralose and Its Effects on Testicular Damage and Male Infertility: Insights into Oxidative Stress and Autophagy.Other primary literatureUnknownActiveEnvironmental health perspectives2025
Chiang YF, Chen YC, Huang KC, et al.
Short-Term Effects of Nonnutritive Sweetener (Sucralose and Saccharin) Consumption on Glycemic Control and Gut Microbiota in Patients With Type 2 Diabetes: Protocol for a Double-Blind, Randomized, Placebo-Controlled, Crossover Trial.Other primary literatureHumanActiveJMIR research protocols2025
Tan HS, Gilcharan Singh HK, Mariappan V, et al.
Re-evaluation of acesulfame K (E 950) as food additive.Other primary literatureUnknownActiveEFSA journal. European Food Safety Authority2025
Castle L, Andreassen M, Aquilina G, et al.
Investigating the impact of aspartame on Alzheimer's disease through network toxicology and molecular docking.Other primary literatureUnknownActiveFrontiers in nutrition2025
Ge L, Sun H, Zhang J, et al.
Improving the communication of uncertainty in food safety on social media: a content analysis of aspartame risk messages.Other primary literatureHumanActiveFrontiers in public health2025
Chen Y, Luo S, Xu L, et al.
Sucralose Promotes Benzo(a)Pyrene-Induced Renal Toxicity in Mice by Regulating P-glycoprotein.Other primary literatureUnknownActiveAntioxidants (Basel, Switzerland)2025
Hu J, Feng J, Bai Y, et al.
Advancements and Challenges in Sucralose Determination: A Comparative Review of Chromatographic, Electrochemical, and Spectrophotometric Methods.ReviewUnknownActiveFoods (Basel, Switzerland)2025
Tkach VV, Morozova TV, de Mascarenhas Gaivão IO, et al.
Effect of Emerging Contaminants (Sucralose) at Relevant Concentrations on Functional Properties in Fish Muscle of Common Carp (<i>Cyprinus carpio</i>).Other primary literatureUnknownActiveFoods (Basel, Switzerland)2025
Saucedo-Vence K, Dublán-García O, Morachis-Valdez AG, et al.
Biological and Behavioral Responses of <i>Drosophila melanogaster</i> to Dietary Sugar and Sucralose.Other primary literatureAnimalActiveInternational journal of molecular sciences2025
Miranda N, Tkach VV, Barros AN, et al.
Molecular Mechanisms of Aspartame-Induced Kidney Renal Papillary Cell Carcinoma Revealed by Network Toxicology and Molecular Docking Techniques.Other primary literatureHumanActiveInternational journal of molecular sciences2025
Huang C, Wei L, Yuan W, et al.
Aspartame and Human Health: A Mini-Review of Carcinogenic and Systemic Effects.ReviewUnknownActiveJournal of xenobiotics2025
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Effects of sucralose supplementation on rumen bacterial community, kynuronine pathway and feeding behavior in small-tailed Han sheepOther primary literatureUnknownUnknownAnimal feed science and technology2025
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Cellular mechanisms underlying the effects of sucralose on keratinocyte proliferation and its contributing roles in epidermal regenerationOther primary literatureUnknownUnknownJournal of functional foods2025
Chatkul P, Satianrapapong W, Wachiradejkul W, et al.
One-pot derivatization spectrofluorimetric method for detection of aspartame in sweetener commercial tablets and soft drinks: Greenness assessments of the methodology.Other primary literatureUnknownActiveLuminescence : the journal of biological and chemical luminescence2024
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Long-term exposure of sucralose induces neuroinflammation and ferroptosis in human microglia cells via SIRT1/NLRP3/IL-1β/GPx4 signaling pathways.Other primary literatureUnknownActiveFood science & nutrition2024
Hacioglu C
Sucralose regulates postprandial blood glucose in mice through intestinal sweet taste receptors Tas1r2/Tas1r3.Other primary literatureAnimalActiveJournal of the science of food and agriculture2024
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Aspartame Intake Delayed Puberty Onset in Female Offspring Rats and Girls.Other primary literatureHuman & animalActiveMolecular nutrition & food research2024
Lin CY, Nguyen NN, Tsai WL, et al.
Amperometric bienzymatic biosensor in flow injection analysis system for determination of aspartame in foods.Other primary literatureUnknownActiveFood science and biotechnology2024
Tangtawewipat T, Thanachasai S
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Sucralose and caffeine as chemical indicators of domestic wastewater contamination in the Laurentian Great Lakes Basin.Other primary literatureHumanActiveEnvironmental monitoring and assessment2024
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The effect of aspartame on accelerating caspase-dependent apoptosis of pancreatic islet via ZIPK/STAT3/caspase 3 signaling pathway.Other primary literatureAnimalActiveJournal of physiology and biochemistry2024
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Neural responses to oral administration of erythritol vs. sucrose and sucralose explain differences in subjective liking ratings.Other primary literatureHumanActiveAppetite2024
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Acesulfame potassium upregulates PD-L1 in HCC cells by attenuating autophagic degradation.Other primary literatureHumanActiveBiochemical and biophysical research communications2024
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The sweet taste receptors in Lemuriformes respond to aspartame, a non-nutritive sweetener and critical residues mediating their taste.Other primary literatureHuman & animalActiveBiochimie2024
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Isolation and characterization of the aspartame-degrading strain Pseudarthrobacter sp. AS-1.Other primary literatureUnknownActiveEnvironmental pollution (Barking, Essex : 1987)2024
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Pathologists' perspective on the study design, analysis, and interpretation of proliferative lesions in a lifetime rodent carcinogenicity bioassay of sucralose.ReviewHuman & animalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2024
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Evaluation of aspartame as a co-former in the preparation of co-amorphous formulations of dipyridamole using spray drying.Other primary literatureUnknownActiveInternational journal of pharmaceutics2024
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Consumption of the nonnutritive sweetener acesulfame potassium increases central precocious puberty risk.Other primary literatureHuman & animalActiveJournal of hazardous materials2024
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Insight into the evolution of microbial communities and resistance genes induced by sucralose in partial nitrification system with triclosan pre-exposure.Other primary literatureUnknownActiveJournal of hazardous materials2024
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Acesulfame potassium triggers inflammatory bowel disease via the inhibition of focal adhesion pathway.Other primary literatureAnimalActiveJournal of hazardous materials2024
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Daytime aspartame intake results in larger influences on body weight, serum corticosterone level, serum/cerebral cytokines levels and depressive-like behaviors in mice than nighttime intake.Other primary literatureAnimalActiveNeurotoxicology2024
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Sucralose and stevia consumption leads to intergenerational alterations in body weight and intestinal expression of histone deacetylase 3.Other primary literatureAnimalActiveNutrition (Burbank, Los Angeles County, Calif.)2024
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Effects of early-life stress followed by access to stevia or sucralose during adolescence on weight gain, glycemia, and anxiety-related behaviors in male and female rats.Other primary literatureAnimalActivePhysiology & behavior2024
Rico JL, Aya-Ramos L, Dueñas Z
Aspartame intake during pregnancy induces placental dysfunction through impaired mitochondrial function and biogenesis modulation.Other primary literatureHuman & animalActivePlacenta2024
Chen YC, Yeh YC, Lin YF, et al.
Sucralose triggers insulin resistance leading to follicular dysplasia in mice.Other primary literatureAnimalActiveReproductive toxicology (Elmsford, N.Y.)2024
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Effects of artificial sweetener acesulfame on soil-dwelling earthworms (Eisenia fetida) and its gut microbiota.Other primary literatureAnimalActiveThe Science of the total environment2024
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Wastewater surveillance of high risk substances in Southern Nevada: Sucralose normalization to translate data for potential public health action.Other primary literatureHumanActiveThe Science of the total environment2024
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Chronic sucralose consumption inhibits farnesoid X receptor signaling and perturbs lipid and cholesterol homeostasis in the mouse livers, potentially by altering gut microbiota functions.Other primary literatureAnimalActiveThe Science of the total environment2024
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Active and passive sampling techniques in headwater streams to characterize acesulfame-K, pharmaceutical and phosphorus contamination from on-site wastewater disposal systems in Canadian rural hamlets.Other primary literatureUnknownActiveThe Science of the total environment2024
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A Novel Sulfatase for Acesulfame Degradation in Wastewater Treatment Plants as Evidenced from Shinella Strains.Other primary literatureUnknownActiveEnvironmental science & technology2024
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Non-nutritive Sweetener Aspartame Disrupts Circadian Behavior and Causes Memory Impairment in Mice.Other primary literatureHuman & animalActiveJournal of agricultural and food chemistry2024
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Formation of Chlorinated Carbohydrate Degradation Products and Amino Acids during Heating of Sucralose in Model Systems and Food.Other primary literatureUnknownActiveJournal of agricultural and food chemistry2024
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Aspartame and Its Microhydrated Aggregates Revealed by Laser Spectroscopy: Water-Sweetener Interactions in the Gas Phase.Other primary literatureUnknownActiveThe journal of physical chemistry. A2024
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Protein Preferential Solvation in (Sucralose + Water) Mixtures.Other primary literatureUnknownActiveThe journal of physical chemistry. B2024
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Induction of the Interdigitated Gel Phase of Hydrated Dipalmitoylphosphatidylcholine Bilayers by the Artificial Sweetener Sucralose.Other primary literatureUnknownActiveThe journal of physical chemistry. B2024
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Assessment of human abuse potential of an unflavored, sucralose-sweetened electronic cigarette in combustible cigarette smokers.Other primary literatureHumanActiveExperimental and clinical psychopharmacology2024
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Aspartame carcinogenic potential revealed through network toxicology and molecular docking insights.Other primary literatureHumanActiveScientific reports2024
Chen D, Hou X
Aspartame use and Parkinson's disease: review of associated effects on neurotransmitters, oxidative stress, and cognition.ReviewHuman & animalActiveNutritional neuroscience2024
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Understanding the link between aspartame and cancer.ReviewHuman & animalActiveExpert review of anticancer therapy2024
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Oral toxicity of an artificial sweetener sucralose on the German cockroach (Blattodea: Ectobiidae) and its impact on water balance and gut microbiome.Other primary literatureAnimalActiveJournal of economic entomology2024
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Aspartame enhances the scavenging activity of mice to low-dose Escherichia coli infection via strengthening macrophage phagocytosis caused by sweet taste receptor activation.Other primary literatureAnimalActiveFASEB journal : official publication of the Federation of American Societies for Experimental Biology2024
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Acceptable daily intake of aspartame aggravates enteritis pathology and systemic inflammation in colitis mouse model.Other primary literatureAnimalActiveJournal of food science2024
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Consumption of sucralose- and acesulfame-potassium-containing diet soda alters the relative abundance of microbial taxa at the species level: findings of two pilot studies.Other primary literatureHumanActiveApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2024
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The non-nutritive sweetener sucralose increases β-arrestin signaling at the constitutively active orphan G protein-coupled receptor GPR52.Other primary literatureUnknownActiveCanadian journal of physiology and pharmacology2024
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Ice cream with sucralose, stevioside, and erythritol as sugar substitutes: Sensory profile and customer preference.Other primary literatureUnknownActiveFood science and technology international = Ciencia y tecnologia de los alimentos internacional2024
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Aspartame, as an artificial sweetener, does not affect renal function and antioxidative states in mice.Other primary literatureAnimalActiveBMC research notes2024
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The impact of sucralose and neotame on the safety of metal precipitation in electronic cigarettes.Other primary literatureUnknownActiveFrontiers in physiology2024
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Sucralose Influences the Productive Performance, Carcass Traits, Blood Components, and Gut Microflora Using 16S rRNA Sequencing of Growing APRI-Line Rabbits.Other primary literatureUnknownActiveAnimals : an open access journal from MDPI2024
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Aspartame Causes Developmental Defects and Teratogenicity in Zebra Fish Embryo: Role of Impaired SIRT1/FOXO3a Axis in Neuron Cells.Other primary literatureUnknownActiveBiomedicines2024
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Sucralose-Enhanced Adipogenesis on Preadipocyte Human Cell Line During Differentiation Process.Other primary literatureHumanActiveInternational journal of molecular sciences2024
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Stochastic dynamic ultraviolet photofragmentation and high collision energy dissociation mass spectrometric kinetics of triadimenol and sucralose.Other primary literatureHumanActiveEnvironmental science and pollution research international2023
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Cardiotoxic and neurobehavioral effects of sucralose and acesulfame in Daphnia: Toward understanding ecological impacts of artificial sweeteners.Other primary literatureAnimalActiveComparative biochemistry and physiology. Toxicology & pharmacology : CBP2023
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Influence of sucralose, acesulfame-k, and their mixture on brain's fish: A study of behavior, oxidative damage, and acetylcholinesterase activity in Daniorerio.Other primary literatureAnimalActiveChemosphere2023
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Oral exposure to an acceptable daily intake dose of aspartame induced a delayed proinflammatory cytokine response in the cerebrospinal fluid of rats.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2023
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The role of study quality in aspartame and cancer epidemiology study reviews.Other primary literatureUnknownActiveGlobal epidemiology2023
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Perspectives on recent reviews of aspartame cancer epidemiology.Other primary literatureUnknownActiveGlobal epidemiology2023
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The neuroprotective potential of turmeric rhizome and bitter melon on aspartame-induced spatial memory impairment in rats.Other primary literatureUnknownActiveHeliyon2023
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Aspartame consumption during pregnancy impairs placenta growth in mice through sweet taste receptor-reactive oxygen species-dependent pathway.Other primary literatureAnimalActiveThe Journal of nutritional biochemistry2023
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In the quest for the ideal sweetener: Aspartame exacerbates selected biomarkers in the fruit fly (Drosophila melanogaster) model of Alzheimer's disease more than sucrose.Other primary literatureUnknownActiveAging brain2023
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Different acesulfame potassium fate and antibiotic resistance propagation pattern in nitrifying and denitrifying sludge systems.Other primary literatureUnknownActiveThe Science of the total environment2023
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Domesticating aquatic plants in hydroponic systems to demonstrate and advance phytoremediation of the artificial sweetener acesulfame.Other primary literatureUnknownActiveThe Science of the total environment2023
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Protein fractionation and shotgun proteomics analysis of enriched bacterial cultures shed new light on the enzymatically catalyzed degradation of acesulfame.Other primary literatureUnknownActiveWater research2023
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Seasonal biodegradation of the artificial sweetener acesulfame enhances its use as a transient wastewater tracer.Other primary literatureUnknownActiveWater research2023
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Carcinogenicity of aspartame, methyleugenol, and isoeugenol.Design not determinedHumanActiveThe Lancet. Oncology2023
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Aspartame-Sweetened Tap Water: Transformation Products and 2,6-Dichloro-1,4-Benzoquinone Formation.Other primary literatureUnknownActiveEnvironmental science & technology2023
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Aspect Ratio Modulation of Sucralose through {002}/{011} Preferred Orientation in Antisolvent Crystallization.Other primary literatureUnknownActiveACS omega2023
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Long-term aspartame and saccharin intakes are related to greater volumes of visceral, intermuscular, and subcutaneous adipose tissue: the CARDIA study.Other primary literatureHumanActiveInternational journal of obesity (2005)2023
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Artificial sweetener sucralose: a possible modulator of autoimmune diseases.Other primary literatureHumanActiveSignal transduction and targeted therapy2023
Kränkel N, Rauch-Kroehnert U
Sucralose: not sweet enough for T cells.Other primary literatureHumanActiveNature reviews. Immunology2023
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Effective inhibition of T95 steel corrosion in 15 wt% HCl solution by aspartame, potassium iodide, and sodium dodecyl sulphate mixture.Other primary literatureUnknownActiveScientific reports2023
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Learning and memory deficits produced by aspartame are heritable via the paternal lineage.Other primary literatureHuman & animalActiveScientific reports2023
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Ambient mass spectrometry and near-infrared spectroscopy - a direct comparison of methods for the quantification of sucralose in e-liquids.Other primary literatureUnknownActiveAnalytical methods : advancing methods and applications2023
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Sucralose and Erythritol - Not Too Sweet.Other primary literatureHumanActiveThe New England journal of medicine2023
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Study on the taste-masking effect and mechanism of Acesulfame K on berberine hydrochloride.Other primary literatureHumanActiveDrug development and industrial pharmacy2023
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Evaluation of DNA damage induced by acesulfame potassium: spectroscopic, molecular modeling simulations and toxicity studies.Other primary literatureHumanActiveJournal of biomolecular structure & dynamics2023
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Toxicological and pharmacokinetic properties of sucralose-6-acetate and its parent sucralose: in vitro screening assays.ReviewHumanActiveJournal of toxicology and environmental health. Part B, Critical reviews2023
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Physiological Impact of the Non-Nutritive Artificial Sweetener, Aspartame, and the Therapeutic Potential of Aqueous Extract of Phyllanthus niruri.Other primary literatureAnimalActiveJournal of medicinal food2023
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Repeated co-exposure to aflatoxin B1 and aspartame disrupts the central nervous system homeostasis: Behavioral, biochemical, and molecular insights.Other primary literatureAnimalActiveJournal of food science2023
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Aspartame and Phenylketonuria: an analysis of the daily phenylalanine intake of aspartame-containing drugs marketed in France.Other primary literatureHumanActiveOrphanet journal of rare diseases2023
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Saccharin and aspartame excite rat retinal neurons.Other primary literatureUnknownActiveFrontiers in ophthalmology2023
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Relationship between Aspartame-Induced Cerebral Cortex Injury and Oxidative Stress, Inflammation, Mitochondrial Dysfunction, and Apoptosis in Sprague Dawley Rats.Other primary literatureUnknownActiveAntioxidants (Basel, Switzerland)2023
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Newborns from Mothers Who Intensely Consumed Sucralose during Pregnancy Are Heavier and Exhibit Markers of Metabolic Alteration and Low-Grade Systemic Inflammation: A Cross-Sectional, Prospective Study.Other primary literatureUnknownActiveBiomedicines2023
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Sucralose Targets the Insulin Signaling Pathway in the SH-SY5Y Neuroblastoma Cell Line.Other primary literatureUnknownActiveMetabolites2023
Čović M, Zjalić M, Mihajlović L, et al.
Biological Assessment of Stevioside and Sucralose as Sucrose Substitutes for Diabetics on STZ-Induced Diabetes in Rats.Other primary literatureHuman & animalActiveMolecules (Basel, Switzerland)2023
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Aspartame and Its Metabolites Cause Oxidative Stress and Mitochondrial and Lipid Alterations in SH-SY5Y Cells.Other primary literatureHumanActiveNutrients2023
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Maternal Intake of Either Fructose or the Artificial Sweetener Acesulfame-K Results in Differential and Sex-Specific Alterations in Markers of Skin Inflammation and Wound Healing Responsiveness in Mouse Offspring: A Pilot Study.Other primary literatureHuman & animalActiveNutrients2023
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The neuroprotective potential of turmeric rhizome and bitter melon on aspartame-induced spatial memory impairment in ratsOther primary literatureUnknownUnknownHeliyon2023
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Consumption of Artificial Sweetener Acesulfame Potassium Increases Preterm Risk and Uterine Contraction with Calcium Influx Increased via Myosin Light Chain Kinase-Myosin Light Chain 20 Related Signaling Pathway.Other primary literatureHuman & animalActiveMolecular nutrition & food research2022
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Sucralose hydrogels: Peering into the reactivity of sucralose versus sucrose under lipase catalyzed trans-esterification.Other primary literatureUnknownActiveCarbohydrate research2022
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Effect of aspartame on survival, morphological and molecular levels of Polyrhachis vicina Roger (Hymenoptera, Formicidae).Other primary literatureAnimalActiveComparative biochemistry and physiology. Toxicology & pharmacology : CBP2022
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Deciphering the adsorption potential of a functionalized green hydrogel nanocomposite for aspartame from aqueous phase.Other primary literatureUnknownActiveChemosphere2022
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Investigating the gut microbiome and metabolome following treatment with artificial sweeteners acesulfame potassium and saccharin in young adult Wistar rats.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2022
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The use of alternative sweeteners (sucralose and stevia) in healthy soft-drink beverages, enhances the bioavailability of polyphenols relative to the classical caloric sucrose.Other primary literatureUnknownActiveFood chemistry2022
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Enhancement of antibiotic resistance dissemination by artificial sweetener acesulfame potassium: Insights from cell membrane, enzyme, energy supply and transcriptomics.Other primary literatureAnimalActiveJournal of hazardous materials2022
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Persulfate-based strategy for promoted acesulfame removal during sludge anaerobic fermentation: Combined chemical and biological effects.Other primary literatureUnknownActiveJournal of hazardous materials2022
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The effects of aspartame on the HTR8/SVneo extravillous trophoblast cell line.Other primary literatureHumanActiveReproductive biology2022
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Acute exposure to environmentally relevant concentrations of sucralose disrupts embryonic development and leads to an oxidative stress response in Danio rerio.Other primary literatureAnimalActiveThe Science of the total environment2022
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The effect of aspartame and sucralose intake on body weight measures and blood metabolites: role of their form (solid and/or liquid) of ingestion.Other primary literatureAnimalActiveThe British journal of nutrition2022
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Acesulfame Anoxic Biodegradation Coupled to Nitrate Reduction by Enriched Consortia and Isolated Shinella spp.Other primary literatureUnknownActiveEnvironmental science & technology2022
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Sucralose as an oxidative-attenuation tracer for characterizing the application of in situ chemical oxidation for the treatment of 1,4-dioxane.Other primary literatureUnknownActiveEnvironmental science. Processes & impacts2022
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Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala.Other primary literatureHuman & animalActiveProceedings of the National Academy of Sciences of the United States of America2022
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The possible protective role of pimpinella anisum oil versus selenium on aspartame induced changes in rat cerebellar cortex: histological, immunohistochemical and electron microscopic study.Other primary literatureAnimalActiveUltrastructural pathology2022
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The Combined Effects of Aspartame and Acesulfame-K Blends on Appetite: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.Meta-analysisHuman & animalActiveAdvances in nutrition (Bethesda, Md.)2022
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Long-term intake of aspartame-induced cardiovascular toxicity is reflected in altered histochemical parameters, evokes oxidative stress, and trigger P53-dependent apoptosis in a mouse model.Other primary literatureAnimalActiveInternational journal of experimental pathology2022
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Phenolic compounds, amino acid profiles, and antibacterial properties of kefir prepared using freeze‐dried Arbutus unedo L. and Tamarindus indica L. fruits and sweetened with stevia, monk fruit sweetener, and aspartameOther primary literatureUnknownUnknownJournal of food processing and preservation.2022
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Novel cannabidiol aspartame combination treatment (JW-100) significantly reduces ISGA score in atopic dermatitis: Results from a randomized double-blinded placebo-controlled interventional study.Randomized controlled trialHumanActiveJournal of cosmetic dermatology2022
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Sucralose, a Non-nutritive Artificial Sweetener Exacerbates High Fat Diet-Induced Hepatic Steatosis Through Taste Receptor Type 1 Member 3.Other primary literatureUnknownActiveFrontiers in nutrition2022
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Low Dose of Sucralose Alter Gut Microbiome in Mice.Other primary literatureUnknownActiveFrontiers in nutrition2022
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Sucralose consumption ameliorates high-fat diet-induced glucose intolerance and liver weight gain in mice.Other primary literatureUnknownActiveFrontiers in nutrition2022
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Influence of Sweeteners (Sucrose, Sucralose, and Stevia) on Bioactive Compounds in a Model System Study for Citrus-Maqui Beverages.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2022
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Trigeminal Stimulus Menthol Masks Bitter Off-Flavor of Artificial Sweetener Acesulfame-K.Other primary literatureUnknownActiveFoods (Basel, Switzerland)2022
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Electrospun Core (HPMC-Acetaminophen)-Shell (PVP-Sucralose) Nanohybrids for Rapid Drug Delivery.Other primary literatureUnknownActiveGels (Basel, Switzerland)2022
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Aspartame Consumption, Mitochondrial Disorder-Induced Impaired Ovarian Function, and Infertility Risk.Other primary literatureHuman & animalActiveInternational journal of molecular sciences2022
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Simultaneous determination of lactulose, sucrose, sucralose, and mannitol using high-performance liquid chromatography-refractive index to estimate intestinal permeability in patients with active ulcerative colitis.Other primary literatureHumanActiveIndian journal of pharmacology2022
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Obesity and Sex-Related Associations With Differential Effects of Sucralose vs Sucrose on Appetite and Reward Processing: A Randomized Crossover Trial.Randomized controlled trialHumanActiveJAMA network open2021
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Could aspartame exacerbate caffeine effects on renal maturation in rat's offspring? A biochemical and histological study.Randomized controlled trialHuman & animalActiveBirth defects research2021
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Insight into the mechanism of aspartame-induced toxicity in male reproductive system following long-term consumption in mice model.Other primary literatureAnimalActiveEnvironmental toxicology2021
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Sucralose Affects Thyroid Hormone Signaling in American Bullfrog [Rana (Lithobates) catesbeiana] Tadpoles.Other primary literatureAnimalActiveArchives of environmental contamination and toxicology2021
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Sucralose can improve glucose tolerance and upregulate expression of sweet taste receptors and glucose transporters in an obese rat model.Other primary literatureAnimalActiveEuropean journal of nutrition2021
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NMR based real-time enzyme kinetics on estimating the inhibitory effect of sucralose in the enzymatic conversion of sucrose.Other primary literatureUnknownActiveBiophysical chemistry2021
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Further Evidence that Habitual Consumption of Sucralose with, but Not without, Carbohydrate Alters Glucose Metabolism.Other primary literatureHuman & animalActiveCell metabolism2021
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Charge-transfer interaction of aspartame and neotame with several π-acceptors: Stoichiometric data.Other primary literatureUnknownActiveData in brief2021
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Aspartame induces cancer stem cell enrichment through p21, NICD and GLI1 in human PANC-1 pancreas adenocarcinoma cells.Other primary literatureHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2021
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Supramolecular nanoassemblies of salmon calcitonin and aspartame for fibrillation inhibition and osteogenesis improvement.Other primary literatureHumanActiveInternational journal of pharmaceutics2021
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Degradation of acesulfame in UV/monochloramine process: Kinetics, transformation pathways and toxicity assessment.Other primary literatureUnknownActiveJournal of hazardous materials2021
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Stevia, sucralose and sucrose added to a maqui-Citrus beverage and their effects on glycemic response in overweight subjects: A randomized clinical trialOther primary literatureUnknownUnknownLWT.2021
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Mechanistic differences in the effects of sucrose and sucralose on the phase stability of lysozyme solutions.Other primary literatureUnknownActiveJournal of molecular liquids2021
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Acesulfame as a suitable sewer tracer on groundwater pollution: A case study before and after the 2016 Mw 7.0 Kumamoto earthquakes.Other primary literatureUnknownActiveThe Science of the total environment2021
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Quantification and cytotoxicity of degradation products (chloropropanols) in sucralose containing e-liquids with propylene glycol and glycerol as base.Other primary literatureHumanActiveToxicology and applied pharmacology2021
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Acesulfame aerobic biodegradation by enriched consortia and Chelatococcus spp.: Kinetics, transformation products, and genomic characterization.Other primary literatureUnknownActiveWater research2021
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Tracking domestic wastewater and road de-icing salt in a municipal drinking water reservoir: Acesulfame and chloride as co-tracers.Other primary literatureUnknownActiveWater research2021
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Gut Microbiota and Its Metabolite Deoxycholic Acid Contribute to Sucralose Consumption-Induced Nonalcoholic Fatty Liver Disease.Other primary literatureAnimalActiveJournal of agricultural and food chemistry2021
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Zebrafish Behavioral Phenomics Links Artificial Sweetener Aspartame to Behavioral Toxicity and Neurotransmitter Homeostasis.Other primary literatureHuman & animalActiveJournal of agricultural and food chemistry2021
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Synthesis and solvent-controlled self-assembly of diketopiperazine-based polyamides from aspartame.Other primary literatureUnknownActiveRSC advances2021
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Specific adsorption and determination of aspartame in soft drinks with a zein magnetic molecularly imprinted modified MGCE sensor.Other primary literatureUnknownActiveRSC advances2021
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Self-assembly of artificial sweetener aspartame adversely affects phospholipid membranes: plausible reason for its deleterious effects.Other primary literatureUnknownActiveChemical communications (Cambridge, England)2021
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Sucralose enhances the susceptibility to dextran sulfate sodium (DSS) induced colitis in mice with changes in gut microbiota.Other primary literatureAnimalActiveFood & function2021
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Aspartame and sucralose extend the lifespan and improve the health status of C. elegans.Other primary literatureHuman & animalActiveFood & function2021
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Chronic administration of caffeine alters acesulfame-K intake and features of fungiform taste buds in mice.Other primary literatureAnimalActiveInternational journal of food sciences and nutrition2021
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Spectroscopic studies on the interaction of aspartame with human serum albumin.Other primary literatureHumanActiveNucleosides, nucleotides & nucleic acids2021
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Sweet Taste Receptor Expression and Its Activation by Sucralose to Regulate Glucose Absorption in Mouse Duodenum.Other primary literatureAnimalActiveJournal of food science2021
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Synbiotic açaí juice (Euterpe oleracea) containing sucralose as noncaloric sweetener: Processing optimization, bioactive compounds, and acceptance during storage.Other primary literatureUnknownActiveJournal of food science2021
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Acesulfame potassium induces dysbiosis and intestinal injury with enhanced lymphocyte migration to intestinal mucosa.Other primary literatureAnimalActiveJournal of gastroenterology and hepatology2021
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Impact of Maternal Intake of Artificial Sweetener, Acesulfame-K, on Metabolic and Reproductive Health Outcomes in Male and Female Mouse Offspring.Other primary literatureUnknownActiveFrontiers in nutrition2021
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Low Doses of Sucralose Alter Fecal Microbiota in High-Fat Diet-Induced Obese Rats.Other primary literatureUnknownActiveFrontiers in nutrition2021
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Long-Term Aspartame Administration Leads to Fibrosis, Inflammasome Activation, and Gluconeogenesis Impairment in the Liver of Mice.Other primary literatureUnknownActiveBiology2021
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Accidental Consumption of Aspartame in Phenylketonuria: Patient Experiences.Other primary literatureHumanActiveNutrients2021
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Saccharin and Sucralose Protect the Glomerular Microvasculature In Vitro against VEGF-Induced Permeability.Other primary literatureHumanActiveNutrients2021
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Consumption of Non-Nutritive Sweetener, Acesulfame Potassium Exacerbates Atherosclerosis through Dysregulation of Lipid Metabolism in ApoE-/- Mice.Other primary literatureHuman & animalActiveNutrients2021
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Erythritol combined with non-nutritive sucralose increases feeding by Drosophila suzukii, quickens mortality and reduces ovipositionOther primary literatureUnknownUnknownCrop Protection2021
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A Review of the Environmental Fate and Effects of Acesulfame-Potassium.ReviewHuman & animalActiveIntegrated environmental assessment and management2020
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Consumption of Diet Soda Sweetened with Sucralose and Acesulfame-Potassium Alters Inflammatory Transcriptome Pathways in Females with Overweight and Obesity.Other primary literatureHumanActiveMolecular nutrition & food research2020
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Assessment of Sucralose, Caffeine and Acetaminophen as Anthropogenic Tracers in Aquatic Systems Across Florida.Other primary literatureHumanActiveBulletin of environmental contamination and toxicology2020
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Identification of aspartame-induced haematopoietic and lymphoid tumours in rats after lifetime treatment.Other primary literatureHuman & animalActiveActa histochemica2020
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Hypothermia induced by central injection of sucralose potentially occurs via monoaminergic pathways in the hypothalamus of chicks.Other primary literatureAnimalActiveComparative biochemistry and physiology. Part A, Molecular & integrative physiology2020
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Zebrafish neuro-behavioral profiles altered by acesulfame (ACE) within the range of "no observed effect concentrations (NOECs)".Other primary literatureAnimalActiveChemosphere2020
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Preparation of an aspartame and N-isopropyl acrylamide copolymer functionalized stationary phase with multi-mode and chiral separation abilities.Other primary literatureUnknownActiveJournal of chromatography. A2020
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Short-Term Consumption of Sucralose with, but Not without, Carbohydrate Impairs Neural and Metabolic Sensitivity to Sugar in Humans.Other primary literatureHumanActiveCell metabolism2020
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Sucralose and acesulfame as an indicator of domestic wastewater contamination in Wuhan surface water.Other primary literatureUnknownActiveEcotoxicology and environmental safety2020
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Sucralose Consumption over 2 Weeks in Healthy Subjects Does Not Modify Fasting Plasma Concentrations of Appetite-Regulating Hormones: A Randomized Clinical Trial.Randomized controlled trialHumanActiveJournal of the Academy of Nutrition and Dietetics2020
Romo-Romo A, Aguilar-Salinas CA, López-Carrasco MG, et al.
Antihyperglycemic and hepatoprotective properties of miracle fruit (Synsepalum dulcificum) compared to aspartame in alloxan-induced diabetic mice.Other primary literatureAnimalActiveJournal of integrative medicine2020
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The hidden hazardous effects of stevia and sucralose consumption in male and female albino mice in comparison to sucrose.Other primary literatureUnknownActiveSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2020
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Aspartame, acesulfame K and sucralose- influence on the metabolism of Escherichia coli.Other primary literatureUnknownActiveMetabolism open2020
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Comprehensive investigations about the binding interaction of acesulfame with human serum albumin.Other primary literatureHumanActiveSpectrochimica acta. Part A, Molecular and biomolecular spectroscopy2020
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"A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII.Other primary literatureHumanActiveJournal of medicinal chemistry2020
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Metabolic effects of sucralose.Other primary literatureHumanActiveNature reviews. Endocrinology2020
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Maternal sucralose intake alters gut microbiota of offspring and exacerbates hepatic steatosis in adulthood.Other primary literatureAnimalActiveGut microbes2020
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A Systematic Review and Activation Likelihood Estimation Meta-Analysis of fMRI Studies on Sweet Taste in Humans.Meta-analysisHumanActiveThe Journal of nutrition2020
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Consumption of the Artificial Sweetener Acesulfame Potassium throughout Pregnancy Induces Glucose Intolerance and Adipose Tissue Dysfunction in Mice.Other primary literatureAnimalActiveThe Journal of nutrition2020
Plows JF, Morton-Jones J, Bridge-Comer PE, et al.
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Anandamide and sucralose change ΔFosB expression in the reward system.Other primary literatureAnimalActiveNeuroreport2020
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Sucralose causes non-selective CD4 and CD8 lymphotoxicity via probable regulation of the MAPK8/APTX/EID1 genes: An in vitro/in silico study.Other primary literatureHumanActiveClinical and experimental pharmacology & physiology2020
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Maternal low-dose aspartame and stevia consumption with an obesogenic diet alters metabolism, gut microbiota and mesolimbic reward system in rat dams and their offspring.Other primary literatureAnimalActiveGut2020
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Chronic sucralose consumption induces elevation of serum insulin in young healthy adults: a randomized, double blind, controlled trial.Randomized controlled trialHumanActiveNutrition journal2020
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PCN-222 metal-organic framework: a selective and highly efficient sorbent for the extraction of aspartame from gum, juice, and diet soft drink before its spectrophotometric determination.Other primary literatureUnknownActiveBMC chemistry2020
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Sucralose promotes accumulation of reactive oxygen species (ROS) and adipogenesis in mesenchymal stromal cells.Other primary literatureHumanActiveStem cell research & therapy2020
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[Kinetics and Mechanism of Sucralose Degradation in Water Using UV-activated Persulfate Process].Other primary literatureUnknownActiveHuan jing ke xue= Huanjing kexue2020
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Long-Term Effect of Aspartame on Male Reproductive System: Evidence for Testicular Histomorphometrics, Hsp70-2 Protein Expression and Biochemical Status.Other primary literatureUnknownActiveInternational journal of fertility & sterility2020
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Sucralose Stimulates Mitochondrial Bioenergetics in Caco-2 Cells.Other primary literatureUnknownActiveFrontiers in nutrition2020
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Sucralose Promotes Colitis-Associated Colorectal Cancer Risk in a Murine Model Along With Changes in Microbiota.Other primary literatureUnknownActiveFrontiers in oncology2020
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Consumption of a Beverage Containing Aspartame and Acesulfame K for Two Weeks Does Not Adversely Influence Glucose Metabolism in Adult Males and Females: A Randomized Crossover Study.Randomized controlled trialHumanActiveInternational journal of environmental research and public health2020
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Differential Cerebral Gustatory Responses to Sucrose, Aspartame, and Stevia Using Gustatory Evoked Potentials in Humans.Other primary literatureHumanActiveNutrients2020
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The Effects of Non-Nutritive Artificial Sweeteners, Aspartame and Sucralose, on the Gut Microbiome in Healthy Adults: Secondary Outcomes of a Randomized Double-Blinded Crossover Clinical Trial.Randomized controlled trialHumanActiveNutrients2020
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High Concentrations of Aspartame Induce Pro-Angiogenic Effects in Ovo and Cytotoxic Effects in HT-29 Human Colorectal Carcinoma Cells.Other primary literatureHumanActiveNutrients2020
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A Quantitative Method for Acesulfame K Using the Taste Sensor.Other primary literatureUnknownActiveSensors (Basel, Switzerland)2020
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[Separation and determination of acesulfame-K in soy sauce by capillary electrophoresis with contactless conductivity detection using liquid-liquid extraction and field-amplified sample injection].Other primary literatureUnknownActiveSe pu = Chinese journal of chromatography2020
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The in vitro cytotoxic, genotoxic, and oxidative damage potentials of the oral artificial sweetener aspartame on cultured human blood cellsOther primary literatureHumanActiveTurkish journal of medical sciences2020
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Effect of in situ aspartame mouthwash to prevent intrinsic and extrinsic erosive tooth wear.Other primary literatureUnknownActiveJournal of clinical and experimental dentistry2020
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Effects of sweetener sucralose on diet preference, growth performance and hematological and biochemical parameters of weaned piglets.Other primary literatureUnknownActiveAsian-Australasian Journal of Animal Sciences2020
Zhang W, He H, Gong L, et al.
An Erythritol-Sweetened Beverage Induces Satiety and Suppresses Ghrelin Compared to Aspartame in Healthy Non-Obese Subjects: A Pilot Study.Other primary literatureUnknownActiveCureus2020
Sorrentino ZA, Smith G, Palm L, et al.
Activation of the sweet taste receptor T1R3 by sucralose attenuates VEGF-induced vasculogenesis in a cell model of the retinal microvascular endothelium.Other primary literatureHumanActiveGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2019
Lizunkova P, Enuwosa E, Chichger H
Behavioral and electrophysiological brain effects of aspartame on well-nourished and malnourished rats.Other primary literatureAnimalActiveMetabolic brain disease2019
Magalhães PCG, Abadie-Guedes R, da Costa Mendonça MAB, et al.
Effect of aspartame on the placenta of adult albino rat. A histological and immunohistochemical study.Other primary literatureAnimalActiveAnnals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft2019
Shalaby AM, Ibrahim MAAH, Aboregela AM
Redox mediators and irradiation improve fenton degradation of acesulfame.Other primary literatureUnknownActiveChemosphere2019
Law JC, Leung KS
Removing acesulfame with the peroxone process: Transformation products, pathways and toxicity.Other primary literatureHumanActiveChemosphere2019
Chow CH, Leung KS
Rapid removal of acesulfame potassium by acid-activated ferrate(VI) under mild alkaline conditions.Other primary literatureUnknownActiveChemosphere2019
Ghosh M, Manoli K, Renaud JB, et al.
Combined effects of artificial sweetener acesulfame on the uptake of Cd in rice (Oryza sativa L.).Other primary literatureUnknownActiveEnvironmental pollution (Barking, Essex : 1987)2019
Xu Y, Li K, Liu Y, et al.
Response to the Letter to the Editor by S. Schiffman and H. Nagle: Revisiting the data and information that has collectively established the safety of low/no-calorie sweeteners, including sucralose.Other primary literatureUnknownActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2019
Roberts A, Lobach AR
Quantitative proteomics reveals systematic dysregulations of liver protein metabolism in sucralose-treated mice.Other primary literatureAnimalActiveJournal of proteomics2019
Liu CW, Chi L, Tu P, et al.
Production and stability of probiotic cocoa juice with sucralose as sugar substitute during refrigerated storageOther primary literatureUnknownUnknownLWT.2019
Santos Filho ALd, Freitas HV, Rodrigues S, et al.
Evaluation of the artificial sweetener sucralose as a sanitary wastewater tracer in Narragansett Bay, Rhode Island, USA.Other primary literatureUnknownActiveMarine pollution bulletin2019
Cantwell MG, Katz DR, Sullivan J, et al.
Suppression of sweet sensing with glucose, but not aspartame, delays gastric emptying and glycemic response.Randomized controlled trialHumanActiveNutrition research (New York, N.Y.)2019
Kashima H, Taniyama K, Sugimura K, et al.
Acesulfame potassium: Its ecotoxicity measured through oxidative stress biomarkers in common carp (Cyprinus carpio).Other primary literatureAnimalActiveThe Science of the total environment2019
Cruz-Rojas C, SanJuan-Reyes N, Fuentes-Benites MPAG, et al.
Alterations to DNA, apoptosis and oxidative damage induced by sucralose in blood cells of Cyprinus carpio.Other primary literatureAnimalActiveThe Science of the total environment2019
Heredia-García G, Gómez-Oliván LM, Orozco-Hernández JM, et al.
Approach for analytical characterization and toxicological assessment of ozonation products in drinking water on the example of acesulfame.Other primary literatureUnknownActiveWater research2019
Buchner EM, Happel O, Schmidt CK, et al.
Use of acetaminophen and sucralose as co-analytes to differentiate sources of human excreta in surface waters.Other primary literatureHumanActiveWater research2019
Currens BJ, Hall AM, Brion GM, et al.
Estimating cumulative wastewater treatment plant discharge influences on acesulfame and Escherichia coli in a highly impacted watershed with a fully-integrated modelling approach.Other primary literatureHumanActiveWater research2019
Hwang HT, Frey SK, Park YJ, et al.
Systematic review and evaluation of aspartame carcinogenicity bioassays using quality criteria.Systematic reviewAnimalActiveRegulatory toxicology and pharmacology : RTP2019
Haighton L, Roberts A, Walters B, et al.
Mutagenicity and genotoxicity studies of aspartame.ReviewHuman & animalActiveRegulatory toxicology and pharmacology : RTP2019
Otabe A, Ohta F, Takumi A, et al.
Histological analyses of the Ishii (1981) rat carcinogenicity study of aspartame and comparison with the Ramazzini Institute studies.Other primary literatureAnimalActiveRegulatory toxicology and pharmacology : RTP2019
Shibui Y, Fujitani S, Iwata H, et al.
Evaluation of aspartame cancer epidemiology studies based on quality appraisal criteria.ReviewHumanActiveRegulatory toxicology and pharmacology : RTP2019
Haighton L, Roberts A, Jonaitis T, et al.
Short-term impact of sucralose consumption on the metabolic response and gut microbiome of healthy adults.Randomized controlled trialHumanActiveThe British journal of nutrition2019
Thomson P, Santibañez R, Aguirre C, et al.
Sucralose-Enhanced Degradation of Electronic Cigarette Liquids during Vaping.Other primary literatureUnknownActiveChemical research in toxicology2019
Duell AK, McWhirter KJ, Korzun T, et al.
Reduced Punch Sticking Propensity of Acesulfame by Salt Formation: Role of Crystal Mechanical Property and Surface Chemistry.Other primary literatureUnknownActiveMolecular pharmaceutics2019
Paul S, Wang C, Wang K, et al.
Self-Assembly of Artificial Sweetener Aspartame Yields Amyloid-like Cytotoxic Nanostructures.Other primary literatureHumanActiveACS nano2019
Anand BG, Prajapati KP, Dubey K, et al.
Role of Water in Sucrose, Lactose, and Sucralose Taste: The Sweeter, The Wetter?Other primary literatureUnknownActiveACS omega2019
Imberti S, McLain SE, Rhys NH, et al.
Toxic emissions resulting from sucralose added to electronic cigarette liquids.Other primary literatureUnknownActiveAerosol science and technology : the journal of the American Association for Aerosol Research2019
El-Hage R, El-Hellani A, Haddad C, et al.
The acute effects of the non-nutritive sweeteners aspartame and acesulfame-K in UK diet cola on glycaemic response.Other primary literatureHumanActiveInternational journal of food sciences and nutrition2019
Solomi L, Rees GA, Redfern KM
Sucralose Increased Susceptibility to Colitis in Rats.Other primary literatureAnimalActiveInflammatory bowel diseases2019
Wang X, Guo J, Liu Y, et al.
May Dysbiosis Caused by Dietary Chemicals Such as Sucralose and Saccharin Be More Detrimental to the Gut and Health Than Antibiotics? How?Other primary literatureHumanActiveInflammatory bowel diseases2019
Qin X
Is Splenda, or Sucralose, Causally Linked to Inflammatory Bowel Disease?Other primary literatureHumanActiveInflammatory bowel diseases2019
Lynch B, Roberts A, Lee Grotz V
Crohn's Disease-Like Ileitis and the Inhibitory Effect of Sucralose on Streptococci.Other primary literatureHumanActiveInflammatory bowel diseases2019
Rodriguez-Palacios A, Cominelli F
Impaired Inactivation of Digestive Proteases in Lower Gut Due to Inhibition of Gut Bacteria by Food Additives Such as Saccharin and Sucralose as Main Cause of Inflammatory Bowel Disease: A Two-Decades-Long Hypothesis Warrants Testing.Other primary literatureHumanActiveInflammatory bowel diseases2019
Qin X
Consumption of Aspartame Associated with Tardive Dyskinesia: New Observation.Other primary literatureHumanActiveJournal of clinical psychopharmacology2019
Schultz J, Furnish K, El-Mallakh RS
Aspartame supplementation in starter accelerates small intestinal epithelial cell cycle and stimulates secretion of glucagon-like peptide-2 in pre-weaned lambs.Other primary literatureAnimalActiveJournal of animal physiology and animal nutrition2019
Sun D, Liu L, Mao S, et al.
A Single 48 mg Sucralose Sip Unbalances Monocyte Subpopulations and Stimulates Insulin Secretion in Healthy Young Adults.Randomized controlled trialHumanActiveJournal of immunology research2019
Gómez-Arauz AY, Bueno-Hernández N, Palomera LF, et al.
EFSA's toxicological assessment of aspartame: was it even-handedly trying to identify possible unreliable positives and unreliable negatives?Other primary literatureUnknownActiveArchives of public health = Archives belges de sante publique2019
Millstone EP, Dawson E
Stability of individual differences in sucralose taste preference.Other primary literatureAnimalActivePloS one2019
Bacharach SZ, Calu DJ
Effect of l-carnitine on aspartame-induced oxidative stress, histopathological changes, and genotoxicity in liver of male rats.Other primary literatureAnimalActiveJournal of basic and clinical physiology and pharmacology2019
Hamza RZ, Al-Eisa RA, Mehana AE, et al.
Aspartame and Sucralose-induced Fatty Changes in Rat Liver.Other primary literatureAnimalActiveJournal of the College of Physicians and Surgeons--Pakistan : JCPSP2019
Haq N, Tafweez R, Saqib S, et al.
Moderate intake of aspartame and sucralose with meals, but not fructose, does not exacerbate energy and glucose metabolism in estrogen-deficient rats.Other primary literatureUnknownActiveJournal of clinical biochemistry and nutrition2019
Ryuk JA, Kang S, Daily JW, et al.
[Determination of Aspartame, Acesulfame Potassium, and Sucralose in Chewing Gum by Dialysis Extraction].Other primary literatureUnknownActiveShokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan2019
Sasaki T, Tahara S, Sakamaki N, et al.
Sated by a Zero-Calorie Sweetener: Wastewater Bacteria Can Feed on Acesulfame.Other primary literatureUnknownActiveFrontiers in microbiology2019
Kleinsteuber S, Rohwerder T, Lohse U, et al.
Synergistic Effects of The Enhancements to Mitochondrial ROS, p53 Activation and Apoptosis Generated by Aspartame and Potassium Sorbate in HepG2 Cells.Other primary literatureHumanActiveMolecules (Basel, Switzerland)2019
Qu D, Jiang M, Huang D, et al.
Efficient Degradation of Acesulfame by Ozone/Peroxymonosulfate Advanced Oxidation Process.Other primary literatureUnknownActiveMolecules (Basel, Switzerland)2019
Shao Y, Pang Z, Wang L, et al.
Sweet Taste as a Predictor of Dietary Intake: A Systematic Review.Systematic reviewHumanActiveNutrients2019
Tan SY, Tucker RM
Energy Expenditure, Carbohydrate Oxidation and Appetitive Responses to Sucrose or Sucralose in Humans: A Pilot Study.Randomized controlled trialHumanActiveNutrients2019
Chern C, Tan SY
Low Calorie Sweeteners Differ in Their Physiological Effects in Humans.ReviewHumanActiveNutrients2019
Hunter SR, Reister EJ, Cheon E, et al.
Effects of Sucralose Ingestion versus Sucralose Taste on Metabolic Responses to an Oral Glucose Tolerance Test in Participants with Normal Weight and Obesity: A Randomized Crossover Trial.Randomized controlled trialHumanActiveNutrients2019
Nichol AD, Salame C, Rother KI, et al.
Environmentally Evaluated New HPLC/UV Method for the Simultaneous Determination of Acesulfame-K, Butylated Hydroxytoluene, and Aspartame and Its Degradant in Chewing Gum.Other primary literatureUnknownActiveJournal of AOAC International2019
Zamzam NS, Abdel Rahman MH, Abdel Ghani MF
Impact of Food Ingredients (Aspartame, Stevia, Prebiotic Oligofructose) on Fertility and Reproductive Outcomes in Obese Rats.Other primary literatureAnimalActiveObesity (Silver Spring, Md.)2018
Cho NA, Klancic T, Nettleton JE, et al.
Astrogliosis and decreased neural viability as consequences of early consumption of aspartame and acesulfame potassium in male Wistar rats.Other primary literatureAnimalActiveMetabolic brain disease2018
Solis-Medina A, Martínez-Magaña JJ, Quintanar-Jurado V, et al.
Hydrophobic interactions of sucralose with protein structures.Other primary literatureAnimalActiveArchives of biochemistry and biophysics2018
Shukla N, Pomarico E, Hecht CJS, et al.
Vitamin E can improve behavioral tests impairment, cell loss, and dendrite changes in rats' medial prefrontal cortex induced by acceptable daily dose of aspartame.Other primary literatureAnimalActiveActa histochemica2018
Rafati A, Noorafshan A, Jahangir M, et al.
Non-isothermal dehydration kinetic study of aspartame hemihydrate using DSC, TGA and DSC-FTIR microspectroscopy.Other primary literatureUnknownActiveAsian journal of pharmaceutical sciences2018
Hsieh WH, Cheng WT, Chen LC, et al.
Effect of sucralose on the enzyme kinetics of invertase using real-time NMR spectroscopy and progress curve analysis.Other primary literatureUnknownActiveCarbohydrate research2018
Her C, Singh J, Krishnan VV
Investigation of the photocatalytic transformation of acesulfame K in the presence of different TiO2-based materials.Other primary literatureUnknownActiveChemosphere2018
López-Muňoz MJ, Daniele A, Zorzi M, et al.
Enhancement of Z-aspartame synthesis by rational engineering of metalloprotease.Other primary literatureUnknownActiveFood chemistry2018
Zhu F, Jiang T, Wu B, et al.
Aspartame as a co-former in co-amorphous systems.Other primary literatureUnknownActiveInternational journal of pharmaceutics2018
Wu W, Löbmann K, Schnitzkewitz J, et al.
Assessment of the origin and transport of four selected emerging micropollutants sucralose, Acesulfame-K, gemfibrozil, and iohexol in a karst spring during a multi-event spring response.Other primary literatureUnknownActiveJournal of contaminant hydrology2018
Doummar J, Aoun M
Oxidative stress evoked damages leading to attenuated memory and inhibition of NMDAR-CaMKII-ERK/CREB signalling on consumption of aspartame in rat model.Other primary literatureAnimalActiveJournal of food and drug analysis2018
Iyaswamy A, Kammella AK, Thavasimuthu C, et al.
The debate over neurotransmitter interaction in aspartame usage.ReviewHuman & animalActiveJournal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia2018
Choudhary AK, Lee YY
A histological assessment of effects of sucralose on liver of albino rats.Other primary literatureHuman & animalActiveMorphologie : bulletin de l'Association des anatomistes2018
Dhurandhar D, Bharihoke V, Kalra S
Effects of sucralose on insulin and glucagon-like peptide-1 secretion in healthy subjects: a randomized, double-blind, placebo-controlled trial.Randomized controlled trialHumanActiveNutrition (Burbank, Los Angeles County, Calif.)2018
Lertrit A, Srimachai S, Saetung S, et al.
No detriment in taste response or expression in offspring of mice fed representative levels of sucrose or non-caloric sucralose while pregnant.Other primary literatureAnimalActivePhysiology & behavior2018
Choo E, Dando R
Effect of AceK (acesulfame potassium) on brain function under dietary restriction in mice.Other primary literatureAnimalActivePhysiology & behavior2018
Ibi D, Suzuki F, Hiramatsu M
Emerging Biodegradation of the Previously Persistent Artificial Sweetener Acesulfame in Biological Wastewater Treatment.Other primary literatureUnknownActiveEnvironmental science & technology2018
Kahl S, Kleinsteuber S, Nivala J, et al.
Human Sweet Receptor T1R3 is Functional in Human Gastric Parietal Tumor Cells (HGT-1) and Modulates Cyclamate and Acesulfame K-Induced Mechanisms of Gastric Acid Secretion.Other primary literatureHumanActiveJournal of agricultural and food chemistry2018
Zopun M, Liszt KI, Stoeger V, et al.
"Seriously Sweet": Acesulfame K Exhibits Selective Inhibition Using Alternative Binding Modes in Carbonic Anhydrase Isoforms.Other primary literatureUnknownActiveJournal of medicinal chemistry2018
Murray AB, Lomelino CL, Supuran CT, et al.
Sweet Binders: Carbonic Anhydrase IX in Complex with Sucralose.Other primary literatureUnknownActiveACS medicinal chemistry letters2018
Lomelino CL, Murray AB, Supuran CT, et al.
Alternative sugars: Sucralose.Design not determinedHumanActiveBritish dental journal2018
Low intake of digestible carbohydrates ameliorates the duodenal absorption of carbohydrates in mice with glucose metabolic disorders induced by sucralose.Other primary literatureHuman & animalActiveFood & function2018
Shi Q
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, et al.
The possible protective effect of N-acetyl-L-cysteine and folic acid in combination against aspartame-induced cerebral cortex neurotoxicity in adult male rats: a light and transmission electron microscopic study.Other primary literatureAnimalActiveUltrastructural pathology2018
Abd-Ellah HF, Abou-Zeid NRA, Nasr NM
Neurophysiological symptoms and aspartame: What is the connection?ReviewHuman & animalActiveNutritional neuroscience2018
Choudhary AK, Lee YY
Metabolic effects of aspartame in adulthood: A systematic review and meta-analysis of randomized clinical trials.Meta-analysisHumanActiveCritical reviews in food science and nutrition2018
Santos NC, de Araujo LM, De Luca Canto G, et al.
Effects of chronic aspartame consumption on MPTP-induced Parkinsonism in male and female mice.Other primary literatureAnimalActiveArchives of physiology and biochemistry2018
Amin SN, Hassan SS, Rashed LA
Intestinal Metabolism and Bioaccumulation of Sucralose In Adipose Tissue In The Rat.Other primary literatureAnimalActiveJournal of toxicology and environmental health. Part A2018
Bornemann V, Werness SC, Buslinger L, et al.
Effects of intraduodenal administration of the artificial sweetener sucralose on blood pressure and superior mesenteric artery blood flow in healthy older subjects.Randomized controlled trialHumanActiveThe American journal of clinical nutrition2018
Pham HT, Stevens JE, Rigda RS, et al.
Sucralose decreases insulin sensitivity in healthy subjects: a randomized controlled trial.Randomized controlled trialHumanActiveThe American journal of clinical nutrition2018
Romo-Romo A, Aguilar-Salinas CA, Brito-Córdova GX, et al.
The not-so-sweet effects of sucralose on blood sugar control.Other primary literatureHumanActiveThe American journal of clinical nutrition2018
Pepino MY
Aspartame Consumption for 12 Weeks Does Not Affect Glycemia, Appetite, or Body Weight of Healthy, Lean Adults in a Randomized Controlled Trial.Randomized controlled trialHumanActiveThe Journal of nutrition2018
Higgins KA, Considine RV, Mattes RD
Author's reply to comments from the International Sweeteners Association (ISA) in response to "Revisiting the safety of aspartame" by Arbind Kumar Choudhary and Etheresia Pretorius Nutrition Reviews 2017;75:718-730.Other primary literatureHumanActiveNutrition reviews2018
Kumar Choudhary A, Pretorius E
Comments from the International Sweeteners Association (ISA) in response to "Revisiting the safety of aspartame" by Arbind Kumar Choudhary and Etheresia Pretorius Nutrition Reviews 2017;75:718-730.Other primary literatureHumanActiveNutrition reviews2018
Pyrogianni V
Pharmacokinetics of Sucralose and Acesulfame-Potassium in Breast Milk Following Ingestion of Diet Soda.Other primary literatureHumanActiveJournal of pediatric gastroenterology and nutrition2018
Rother KI, Sylvetsky AC, Walter PJ, et al.
Comparative stability of aspartame and neotame in yoghurtOther primary literatureUnknownUnknownInternational Journal of Dairy Technology2018
Kumari A, Arora S, Choudhary S, et al.
Activation of the sweet taste receptor, T1R3, by the artificial sweetener sucralose regulates the pulmonary endothelium.Other primary literatureAnimalActiveAmerican journal of physiology. Lung cellular and molecular physiology2018
Harrington EO, Vang A, Braza J, et al.
Effect of developmental NMDAR antagonism with CGP 39551 on aspartame-induced hypothalamic and adrenal gene expression.Other primary literatureAnimalActivePloS one2018
Collison KS, Inglis A, Shibin S, et al.
Role of L-carnitine in protection against the cardiac oxidative stress induced by aspartame in Wistar albino rats.Other primary literatureAnimalActivePloS one2018
Al-Eisa RA, Al-Salmi FA, Hamza RZ, et al.
Aspartame: Should Individuals with Type II Diabetes be Taking it?ReviewHuman & animalActiveCurrent diabetes reviews2018
Choudhary AK
Health Implications Associated with Aspartame Consumption: A Substantial Review.ReviewHuman & animalActivePakistan journal of biological sciences : PJBS2018
Naik AQ, Zafar T, Shrivastava VK
The effect of aspartame and pH changes on the erosive potential of cola drinks in bovine enamel: An in vitro study.Other primary literatureUnknownActiveJournal of clinical and experimental dentistry2018
Rios D, Ionta FQ, Rebelato R, et al.
Sucralose activates an ERK1/2-ribosomal protein S6 signaling axis.Other primary literatureUnknownActiveFEBS open bio2017
Guerra ML, Kalwat MA, McGlynn K, et al.
Neuroprotective and Ameliorating Impacts of Omega-3 Against Aspartame-induced Neuronal and Astrocytic Degeneration.Other primary literatureAnimalActiveAnatomical record (Hoboken, N.J. : 2007)2017
Ali EMT, Sonpol HMA
Renal-protective and ameliorating impacts of omega-3 fatty acids against aspartame damaged MDCK cells.Other primary literatureAnimalActiveBioFactors (Oxford, England)2017
Pandurangan M, Enkhtaivan G, Veerappan M, et al.
Supplementation of oligofructose, but not sucralose, decreases high-fat diet induced body weight gain in mice independent of gustducin-mediated gut hormone release.Other primary literatureAnimalActiveMolecular nutrition & food research2017
Steensels S, Cools L, Avau B, et al.
Sucralose Increases Antimicrobial Resistance and Stimulates Recovery of Escherichia coli Mutants.Other primary literatureUnknownActiveCurrent microbiology2017
Qu Y, Li R, Jiang M, et al.
A theoretical and experimental study of calcium, iron, zinc, cadmium, and sodium ions absorption by aspartame.Other primary literatureUnknownActiveJournal of biological physics2017
Mahnam K, Raisi F
Aspartame and Soft Drink-Mediated Neurotoxicity in Rats: Implication of Oxidative Stress, Apoptotic Signaling Pathways, Electrolytes and Hormonal Levels.Other primary literatureAnimalActiveMetabolic brain disease2017
Lebda MA, Sadek KM, El-Sayed YS
Improvement in Thermal Stability of Sucralose by γ-Cyclodextrin Metal-Organic Frameworks.Other primary literatureUnknownActivePharmaceutical research2017
Lv N, Guo T, Liu B, et al.
Ecotoxicological assessments show sucralose and fluoxetine affect the aquatic plant, Lemna minor.Other primary literatureUnknownActiveAquatic toxicology (Amsterdam, Netherlands)2017
Amy-Sagers C, Reinhardt K, Larson DM
Removal of artificial sweetener aspartame from aqueous media by electrochemical advanced oxidation processes.Other primary literatureUnknownActiveChemosphere2017
Lin H, Oturan N, Wu J, et al.
Oxidative degradation of emerging micropollutant acesulfame in aqueous matrices by UVA-induced H2O2/Fe2+ and S2O82-/Fe2+ processes.Other primary literatureUnknownActiveChemosphere2017
Kattel E, Trapido M, Dulova N
Phototransformation of Acesulfame K in surface waters: Comparison of two techniques for the measurement of the second-order rate constants of indirect photodegradation, and modelling of photoreaction kinetics.Other primary literatureUnknownActiveChemosphere2017
Minella M, Giannakis S, Mazzavillani A, et al.
Sucralose Suppresses Food Intake.Other primary literatureHumanActiveCell metabolism2017
Park JH, Carvalho GB, Murphy KR, et al.
Chronic Sucralose or L-Glucose Ingestion Does Not Suppress Food Intake.Other primary literatureHuman & animalActiveCell metabolism2017
Wang QP, Simpson SJ, Herzog H, et al.
Disruption of gel phase lipid packing efficiency by sucralose studied with merocyanine 540.Other primary literatureUnknownActiveColloids and surfaces. B, Biointerfaces2017
Barker M, Kennedy A
Critical review of the current literature on the safety of sucralose.ReviewHuman & animalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2017
Magnuson BA, Roberts A, Nestmann ER
Simultaneous determination of aspartame, cyclamate, saccharin and acesulfame-K in powder tabletop sweeteners by FT-Raman spectroscopy associated with the multivariate calibration: PLS, iPLS and siPLS models were compared.Other primary literatureUnknownActiveFood research international (Ottawa, Ont.)2017
Duarte LM, Paschoal D, Izumi CMS, et al.
Expedited development of a high dose orally disintegrating metformin tablet enabled by sweet salt formation with acesulfame.Other primary literatureUnknownActiveInternational journal of pharmaceutics2017
Wang C, Hu S, Sun CC
Acetylation and deacetylation for sucralose preparation by a newly isolated Bacillus amyloliquefaciens WZS01.Other primary literatureUnknownActiveJournal of bioscience and bioengineering2017
Sun J, Chen L, Lou B, et al.
Oxidative transformation of artificial sweetener acesulfame by permanganate: Reaction kinetics, transformation products and pathways, and ecotoxicity.Other primary literatureUnknownActiveJournal of hazardous materials2017
Yin K, Li F, Wang Y, et al.
Aspartame and the hippocampus: Revealing a bi-directional, dose/time-dependent behavioural and morphological shift in mice.Other primary literatureAnimalActiveNeurobiology of learning and memory2017
Onaolapo AY, Onaolapo OJ, Nwoha PU
Long-term soft drink and aspartame intake induces hepatic damage via dysregulation of adipocytokines and alteration of the lipid profile and antioxidant status.Other primary literatureAnimalActiveNutrition research (New York, N.Y.)2017
Lebda MA, Tohamy HG, El-Sayed YS
Silymarin attenuates aspartame-induced variation in mouse behaviour, cerebrocortical morphology and oxidative stress markers.Other primary literatureUnknownActivePathophysiology : the official journal of the International Society for Pathophysiology2017
Onaolapo AY, Abdusalam SZ, Onaolapo OJ
Chronic aspartame intake causes changes in the trans-sulphuration pathway, glutathione depletion and liver damage in mice.Other primary literatureHuman & animalActiveRedox biology2017
Finamor I, Pérez S, Bressan CA, et al.
Interaction of sucralose with whey protein: Experimental and molecular modeling studies.Other primary literatureUnknownActiveSpectrochimica acta. Part A, Molecular and biomolecular spectroscopy2017
Zhang H, Sun S, Wang Y, et al.
Facile and large-scale synthesis of green-emitting carbon nanodots from aspartame and the applications for ferric ions sensing and cell imaging.Other primary literatureUnknownActiveScience bulletin2017
Zhang X, Chen Y, Ding SN
Toxicological hazard induced by sucralose to environmentally relevant concentrations in common carp (Cyprinus carpio).Other primary literatureAnimalActiveThe Science of the total environment2017
Saucedo-Vence K, Elizalde-Velázquez A, Dublán-García O, et al.
Investigation of ozonation kinetics and transformation products of sucralose.Other primary literatureUnknownActiveThe Science of the total environment2017
Hu R, Zhang L, Hu J
Biodegradation of the artificial sweetener acesulfame in biological wastewater treatment and sandfilters.Other primary literatureUnknownActiveWater research2017
Castronovo S, Wick A, Scheurer M, et al.
Transformation of acesulfame in chlorination: Kinetics study, identification of byproducts, and toxicity assessment.Other primary literatureHumanActiveWater research2017
Li AJ, Wu P, Law JC, et al.
A 12-week randomized clinical trial investigating the potential for sucralose to affect glucose homeostasis.Randomized controlled trialHumanActiveRegulatory toxicology and pharmacology : RTP2017
Grotz VL, Pi-Sunyer X, Porte D Jr, et al.
Oxidative stress evoked damages on rat sperm and attenuated antioxidant status on consumption of aspartame.Other primary literatureAnimalActiveInternational journal of impotence research2017
Ashok I, Poornima PS, Wankhar D, et al.
Effects of aspartame-, monk fruit-, stevia- and sucrose-sweetened beverages on postprandial glucose, insulin and energy intake.Randomized controlled trialHumanActiveInternational journal of obesity (2005)2017
Tey SL, Salleh NB, Henry J, et al.
Early maternal separation induces preference for sucrose and aspartame associated with increased blood glucose and hyperactivity.Other primary literatureHuman & animalActiveFood & function2017
Aya-Ramos L, Contreras-Vargas C, Rico JL, et al.
Boronic acid recognition of non-interacting carbohydrates for biomedical applications: increasing fluorescence signals of minimally interacting aldoses and sucralose.Other primary literatureUnknownActiveOrganic & biomolecular chemistry2017
Resendez A, Halim MA, Singh J, et al.
Dose and time dependent ototoxicity of aspartame in rats.Other primary literatureAnimalActiveActa oto-laryngologica2017
Ozturan O, Dogan R, Tugrul S, et al.
Plasma concentrations of sucralose in children and adults.Other primary literatureUnknownActiveToxicological and environmental chemistry2017
Sylvetsky AC, Bauman V, Blau JE, et al.
Simultaneous determination of sodium saccharin, aspartame, acesulfame-K and sucralose in food consumed in Korea using high-performance liquid chromatography and evaporative light-scattering detection.Other primary literatureHumanActiveFood additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment2017
Lee Y, Do B, Lee G, et al.
Longitudinal modelling of the exposure of young UK patients with PKU to acesulfame K and sucralose.Other primary literatureHumanActiveFood additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment2017
O'Sullivan AJ, Pigat S, O'Mahony C, et al.
Aspartame, a bittersweet pill.Other primary literatureHuman & animalActiveCarcinogenesis2017
Paolini M, Vivarelli F, Sapone A, et al.
Sweetener Intake by Rats Selectively Bred for Differential Saccharin Intake: Sucralose, Stevia, and Acesulfame Potassium.Other primary literatureAnimalActiveChemical senses2017
Dess NK, Dobson K, Roberts BT, et al.
Revisiting the safety of aspartame.ReviewHuman & animalCorrectedNutrition reviews2017
Choudhary AK, Pretorius E
Aspartame Intake Relates to Coronary Plaque Burden and Inflammatory Indices in Human Immunodeficiency Virus.Other primary literatureUnknownActiveOpen Forum Infectious Diseases2017
Hall LN, Sanchez LR, Hubbard J, et al.
Aspartame inhibits migration of human intestinal epithelial cellsOther primary literatureUnknownUnknownJournal of food biochemistry.2017
Sawadsopanon T, Meksawan K, Chanvorachote P
Inhibition of the gut enzyme intestinal alkaline phosphatase may explain how aspartame promotes glucose intolerance and obesity in mice.Other primary literatureAnimalActiveApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2017
Gul SS, Hamilton AR, Munoz AR, et al.
Antiglycating potential of acesulfame potassium: an artificial sweetener.Other primary literatureUnknownActiveApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme2017
Ali A, More TA, Hoonjan AK, et al.
The artificial sweetener acesulfame potassium affects the gut microbiome and body weight gain in CD-1 mice.Other primary literatureAnimalActivePloS one2017
Bian X, Chi L, Gao B, et al.
The effect of sucralose on flavor sweetness in electronic cigarettes varies between delivery devices.Other primary literatureHumanActivePloS one2017
Rosbrook K, Erythropel HC, DeWinter TM, et al.
Statement on the validity of the conclusions of a mouse carcinogenicity study on sucralose (E 955) performed by the Ramazzini Institute.Other primary literatureUnknownActiveEFSA journal. European Food Safety Authority2017
Aguilar F, Crebelli R, Di Domenico A, et al.
Rheological and sensory performance of a protein-based sweetener (MNEI), sucrose, and aspartame in yogurt.Other primary literatureHuman & animalActiveJournal of dairy science2017
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Gut Microbiome Response to Sucralose and Its Potential Role in Inducing Liver Inflammation in Mice.Other primary literatureUnknownActiveFrontiers in physiology2017
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Nephrotoxic Effect of Aspartame as an Artificial Sweetener: a Brief Review.ReviewHuman & animalActiveIranian journal of kidney diseases2017
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The non-metabolizable sucrose analog sucralose is a potent inhibitor of hormogonium differentiation in the filamentous cyanobacterium Nostoc punctiforme.Other primary literatureUnknownActiveArchives of microbiology2016
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Cross-over studies underestimate energy compensation: The example of sucrose-versus sucralose-containing drinks.Randomized controlled trialHumanActiveAppetite2016
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A novel library of saccharin and acesulfame derivatives as potent and selective inhibitors of carbonic anhydrase IX and XII isoforms.Other primary literatureHumanActiveBioorganic & medicinal chemistry2016
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Sucralose Promotes Food Intake through NPY and a Neuronal Fasting Response.Other primary literatureAnimalActiveCell metabolism2016
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The effect of modifying the distribution of sucralose and quinine on bitterness suppression in model gelsOther primary literatureUnknownUnknownFood Quality and Preference.2016
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Alterations in behaviour, cerebral cortical morphology and cerebral oxidative stress markers following aspartame ingestion.Other primary literatureAnimalActiveJournal of chemical neuroanatomy2016
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Effect of long term-administration of aspartame on the ultrastructure of sciatic nerve.Other primary literatureUnknownActiveJournal of microscopy and ultrastructure2016
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Differential effects of early-life NMDA receptor antagonism on aspartame-impaired insulin tolerance and behavior.Other primary literatureAnimalActivePhysiology & behavior2016
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Use of two artificial sweeteners, cyclamate and acesulfame, to identify and quantify wastewater contributions in a karst spring.Other primary literatureUnknownActiveThe Science of the total environment2016
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The oxidative stress in the liver of Carassius auratus exposed to acesulfame and its UV irradiance products.Other primary literatureAnimalActiveThe Science of the total environment2016
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Investigation of role of aspartame on apoptosis process in HeLa cells -->.Other primary literatureUnknownActiveSaudi journal of biological sciences2016
Pandurangan M, Enkhtaivan G, Mistry B, et al.
Degradation of sucralose in groundwater and implications for age dating contaminated groundwater.Other primary literatureUnknownActiveWater research2016
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Photocatalytic transformation of acesulfame: Transformation products identification and embryotoxicity study.Other primary literatureAnimalActiveWater research2016
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Efficient Extracellular Expression of Metalloprotease for Z-Aspartame Synthesis.Other primary literatureUnknownActiveJournal of agricultural and food chemistry2016
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Variation in the TAS2R31 bitter taste receptor gene relates to liking for the nonnutritive sweetener Acesulfame-K among children and adults.Other primary literatureHumanActiveScientific reports2016
Bobowski N, Reed DR, Mennella JA
Cytotoxic effects of aspartame on human cervical carcinoma cells.Other primary literatureUnknownActiveToxicology research2016
Pandurangan M, Enkhtaivan G, Kim DH
Sucralose Non-Carcinogenicity: A Review of the Scientific and Regulatory Rationale.ReviewHuman & animalActiveNutrition and cancer2016
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Sucralose administered in feed, beginning prenatally through lifespan, induces hematopoietic neoplasias in male swiss mice.Other primary literatureAnimalActiveInternational journal of occupational and environmental health2016
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Increased Digestive Proteases and Decreased β-Glucuronidase in Feces of Rats Treated with Sucralose and Saccharin-Another Critical Evidence That These Dietary Chemicals May Be Important Causative Factors for Inflammatory Bowel Disease.Other primary literatureAnimalActiveInflammatory bowel diseases2016
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Development of an HPLC Method with an ODS Column to Determine Low Levels of Aspartame Diastereomers in Aspartame.Other primary literatureUnknownActivePloS one2016
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Sucralose, an activator of the glucose-sensing receptor, increases ATP by calcium-dependent and -independent mechanisms.Other primary literatureAnimalActiveEndocrine journal2016
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Sucralose as co-crystal co-former for hydrochlorothiazide: development of oral disintegrating tablets.Other primary literatureUnknownActiveDrug development and industrial pharmacy2016
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Exploring the biological consequences of conformational changes in aspartame models containing constrained analogues of phenylalanine.Other primary literatureUnknownActiveJournal of enzyme inhibition and medicinal chemistry2016
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Fructose acute effects on glucose, insulin, and triglyceride after a solid meal compared with sucralose and sucrose in a randomized crossover study.Randomized controlled trialHumanActiveThe American journal of clinical nutrition2016
Gallagher C, Keogh JB, Pedersen E, et al.
Effects of aspartame on hsp70, bcl-2 and bax expression in immune organs of Wistar albino rats.Other primary literatureUnknownActiveJournal of biomedical research2016
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Fabrication of a novel electrospun molecularly imprinted nanomembrane coupled with high-performance liquid chromatography for the selective separation and determination of acesulfame.Other primary literatureUnknownActiveJournal of separation science2015
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Rapid ultra-trace analysis of sucralose in multiple-origin aqueous samples by online solid-phase extraction coupled to high-resolution mass spectrometry.Other primary literatureUnknownActiveAnalytical and bioanalytical chemistry2015
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Modified high-density lipoproteins by artificial sweetener, aspartame, and saccharin, showed loss of anti-atherosclerotic activity and toxicity in zebrafish.Other primary literatureHuman & animalActiveCardiovascular toxicology2015
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Aspartame: safety and stability in kalakand.Other primary literatureUnknownActiveJournal of food science and technology2015
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Fortification with iron chelate and substitution of sucrose by sucralose in light uvaia sherbet (Eugenia pyriformis Cambess): physical, chemical and sensory characteristics.Other primary literatureUnknownActiveJournal of food science and technology2015
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Sub-minute method for simultaneous determination of aspartame, cyclamate, acesulfame-K and saccharin in food and pharmaceutical samples by capillary zone electrophoresis.Other primary literatureUnknownActiveJournal of chromatography. A2015
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Choudhary AK, Sheela Devi R
"Aspartame: A review of genotoxicity data".ReviewHuman & animalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2015
Kirkland D, Gatehouse D
Oxidant stress evoked damage in rat hepatocyte leading to triggered nitric oxide synthase (NOS) levels on long term consumption of aspartame.Other primary literatureUnknownActiveJournal of food and drug analysis2015
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Probiotic clarified apple juice with oligofructose or sucralose as sugar substitutes: Sensory profile and acceptabilityOther primary literatureUnknownUnknownLWT.2015
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Examination of the perception of sweet- and bitter-like taste qualities in sucralose preferring and avoiding rats.Other primary literatureAnimalActivePhysiology & behavior2015
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Quantification of acesulfame potassium in processed foods by quantitative 1H NMR.Other primary literatureUnknownActiveTalanta2015
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Molecularly imprinted sol-gel nanofibers based solid phase microextraction coupled on-line with high performance liquid chromatography for selective determination of acesulfame.Other primary literatureUnknownActiveTalanta2015
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Sucralose Destabilization of Protein Structure.Other primary literatureUnknownActiveThe journal of physical chemistry letters2015
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Sucralose enhances GLP-1 release and lowers blood glucose in the presence of carbohydrate in healthy subjects but not in patients with type 2 diabetes.Other primary literatureHumanActiveEuropean journal of clinical nutrition2015
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Aspartame Attenuates 2, 4-Dinitrofluorobenzene-Induced Atopic Dermatitis-Like Clinical Symptoms in NC/Nga Mice.Other primary literatureHuman & animalActiveThe Journal of investigative dermatology2015
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Oral health and nutrition: Aspartame and other materials.Other primary literatureHumanActiveBritish dental journal2015
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de Oliveira DN, de Menezes M, Catharino RR
Aspartame and Risk of Cancer: A Meta-analytic Review.Meta-analysisHumanActiveArchives of environmental & occupational health2015
Mallikarjun S, Sieburth RM
Dietary exposure to benzoates (E210-E213), parabens (E214-E219), nitrites (E249-E250), nitrates (E251-E252), BHA (E320), BHT (E321) and aspartame (E951) in children less than 3 years old in France.Other primary literatureHumanActiveFood additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment2015
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Increase of methanol in exhaled breath quantified by SIFT-MS following aspartame ingestion.Other primary literatureHumanActiveJournal of breath research2015
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Sugars as hydroxyl radical scavengers: proof-of-concept by studying the fate of sucralose in Arabidopsis.Other primary literatureUnknownActiveThe Plant journal : for cell and molecular biology2015
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Reduced sweet and fatty fluid intake after Roux-en-Y gastric bypass in rats is dependent on experience without change in stimulus motivational potency.Other primary literatureAnimalActiveAmerican journal of physiology. Regulatory, integrative and comparative physiology2015
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Impact of aspartame and saccharin on the rat liver: Biochemical, molecular, and histological approach.Other primary literatureAnimalActiveInternational journal of immunopathology and pharmacology2015
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Aspartame induces angiogenesis in vitro and in vivo models.Other primary literatureAnimalActiveHuman & experimental toxicology2015
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Green synthesis of gold nanoparticles using aspartame and their catalytic activity for p-nitrophenol reduction.Other primary literatureUnknownActiveNanoscale research letters2015
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[Development of a New Method for Determination of Sodium Saccharin and Acesulfame Potassium with the Aid of Coagulant].Other primary literatureUnknownActiveShokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan2015
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Acute effect of aspartame-induced oxidative stress in Wistar albino rat brain.Other primary literatureUnknownActiveJournal of biomedical research2015
Ashok I, Sheeladevi R, Wankhar D
The carcinogenic effects of aspartame: The urgent need for regulatory re-evaluation.ReviewHuman & animalActiveAmerican journal of industrial medicine2014
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Simultaneous determination of aspartame, acesulfame-K, saccharin, citric acid and sodium benzoate in various food products using HPLC–CAD–UV/DADOther primary literatureUnknownUnknownEuropean food research & technology.2014
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Monosodium glutamate and aspartame in perceived pain in fibromyalgia.Randomized controlled trialHumanActiveRheumatology international2014
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A review of the genotoxic and carcinogenic effects of aspartame: does it safe or not?Other primary literatureUnknownActiveCytotechnology2014
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Study on the interaction of a copper(II) complex containing the artificial sweetener aspartame with human serum albumin.Other primary literatureHumanActiveMolecular biology reports2014
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The protective effect of N-acetylcysteine on oxidative stress in the brain caused by the long-term intake of aspartame by rats.Other primary literatureAnimalActiveNeurochemical research2014
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Aspartame downregulates 3T3-L1 differentiation.Other primary literatureAnimalActiveIn vitro cellular & developmental biology. Animal2014
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Prooxidative effects of aspartame on antioxidant defense status in erythrocytes of rats.Other primary literatureAnimalActiveJournal of biosciences2014
Prokic MD, Paunovic MG, Matic MM, et al.
Direct large volume injection ultra-high performance liquid chromatography-tandem mass spectrometry determination of artificial sweeteners sucralose and acesulfame in well water.Other primary literatureUnknownActiveJournal of chromatography. A2014
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Cyclic tertiary sulfamates: selective inhibition of the tumor-associated carbonic anhydrases IX and XII by N- and O-substituted acesulfame derivatives.Other primary literatureHumanActiveEuropean journal of medicinal chemistry2014
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Aspartame-induced apoptosis in PC12 cells.Other primary literatureAnimalActiveEnvironmental toxicology and pharmacology2014
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Influence of carboxymethyl cellulose and sodium alginate on sweetness intensity of Aspartame.Other primary literatureHumanActiveFood chemistry2014
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N-acetylcysteine protects the rat kidney against aspartame-induced oxidative stress.Other primary literatureUnknownActiveFree radical biology & medicine2014
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Demonstrating sucralose as a monitor of full-scale UV/AOP treatment of trace organic compounds.Other primary literatureUnknownActiveJournal of hazardous materials2014
Lester Y, Ferrer I, Thurman EM, et al.
Cognitive and biochemical effects of monosodium glutamate and aspartame, administered individually and in combination in male albino mice.Other primary literatureAnimalActiveNeurotoxicology and teratology2014
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Biochemical responses and mitochondrial mediated activation of apoptosis on long-term effect of aspartame in rat brain.Other primary literatureAnimalActiveRedox biology2014
Ashok I, Sheeladevi R
Interaction of a copper (II) complex containing an artificial sweetener (aspartame) with calf thymus DNA.Other primary literatureAnimalActiveSpectrochimica acta. Part A, Molecular and biomolecular spectroscopy2014
Shahabadi N, Khodaei MM, Kashanian S, et al.
Quantification of long-term wastewater fluxes at the surface water/groundwater-interface: an integrative model perspective using stable isotopes and acesulfame.Other primary literatureUnknownActiveThe Science of the total environment2014
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Transformation of the artificial sweetener acesulfame by UV light.Other primary literatureUnknownActiveThe Science of the total environment2014
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Aspartame-stabilized gold-silver bimetallic biocompatible nanostructures with plasmonic photothermal properties, antibacterial activity, and long-term stability.Other primary literatureHumanActiveJournal of the American Chemical Society2014
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Efficient hydrolysis of cellulose over a novel sucralose-derived solid acid with cellulose-binding and catalytic sites.Other primary literatureUnknownCorrectedJournal of agricultural and food chemistry2014
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Synthesis of Aspartame by Thermolysin: An X-ray Structural Study.Other primary literatureUnknownActiveACS medicinal chemistry letters2014
Birrane G, Bhyravbhatla B, Navia MA
Acesulfame-K and pharmaceuticals as co-tracers of municipal wastewater in a receiving river.Other primary literatureUnknownActiveEnvironmental science. Processes & impacts2014
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Allergic reaction caused by acesulfame potassium in foods.Other primary literatureHumanActiveContact dermatitis2014
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Chronic Effect of Aspartame on Ionic Homeostasis and Monoamine Neurotransmitters in the Rat Brain.Other primary literatureAnimalActiveInternational journal of toxicology2014
Abhilash M, Alex M, Mathews VV, et al.
Aspartame Administration and Insulin Treatment Altered Brain Levels of CYP2E1 and CYP3A2 in Streptozotocin-Induced Diabetic Rats.Other primary literatureAnimalActiveInternational journal of toxicology2014
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Very low calorie diet without aspartame in obese subjects: improved metabolic control after 4 weeks treatment.Observational studyHumanActiveNutrition journal2014
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Sucralose induces biochemical responses in Daphnia magna.Other primary literatureAnimalActivePloS one2014
Eriksson Wiklund AK, Adolfsson-Erici M, Liewenborg B, et al.
Low-dose aspartame consumption differentially affects gut microbiota-host metabolic interactions in the diet-induced obese rat.Other primary literatureAnimalActivePloS one2014
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Pepino MY, Klein S
Ameliorative effect of Pimpinella anisum oil on immunohistochemical and ultrastuctural changes of cerebellum of albino rats induced by aspartame.Other primary literatureAnimalActiveUltrastructural pathology2014
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Bienzymatic biosensor for rapid detection of aspartame by flow injection analysis.Other primary literatureHuman & animalActiveSensors (Basel, Switzerland)2014
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Development of a sweetness sensor for aspartame, a positively charged high-potency sweetener.Other primary literatureUnknownActiveSensors (Basel, Switzerland)2014
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[Aspartame: Europe finally declares this sweetening agent not guilty].Other primary literatureHumanActiveRevue medicale suisse2014
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Effect of fructose and sucralose on flow-mediated vasodilatation in healthy, white European males.Randomized controlled trialHumanActiveJPMA. The Journal of the Pakistan Medical Association2014
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[Determination of sucralose in foods and beverages by ultraviolet derivatization-high performance liquid chromatography].Other primary literatureUnknownActiveSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition2014
Chen LY, Liu YP, Ran XQ, et al.
Water-compatible 'aspartame'-imprinted polymer grafted on silica surface for selective recognition in aqueous solution.Other primary literatureUnknownActiveAnalytical and bioanalytical chemistry2013
Singh M, Singh M, Kumar A, et al.
Effect of the artificial sweetener, acesulfame potassium, a sweet taste receptor agonist, on glucose uptake in small intestinal cell lines.Other primary literatureHuman & animalActiveJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2013
Zheng Y, Sarr MG
Rebaudioside A and Rebaudioside D bitterness do not covary with Acesulfame K bitterness or polymorphisms in TAS2R9 and TAS2R31.Other primary literatureUnknownActiveChemosensory perception2013
Allen AL, McGeary JE, Hayes JE
Assessment of stability of binary sweetener blend (aspartame x acesulfame-K) during storage in whey lemon beverage.Other primary literatureUnknownActiveJournal of food science and technology2013
Arora S, Shendurse AM, Sharma V, et al.
Sucralose.ReviewHuman & animalActiveProfiles of drug substances, excipients, and related methodology2013
AlDeeb OA, Mahgoub H, Foda NH
Saccharin and aspartame, compared with sucrose, induce greater weight gain in adult Wistar rats, at similar total caloric intake levels.Other primary literatureAnimalActiveAppetite2013
Feijó FM, Ballard CR, Foletto KC, et al.
Aspartame, low-calorie sweeteners and disease: regulatory safety and epidemiological issues.ReviewHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2013
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Effect of aspartame and other additives on the growth and thermal inactivation of Zygosaccharomyces bailii in acidified aqueous systemsOther primary literatureUnknownUnknownFood research international (Ottawa, Ont.)2013
Gliemmo MF, Schelegueda LI, Gerschenson LN, et al.
A hydro/organo/hybrid gelator: a peptide lipid with turning aspartame head groups.Other primary literatureUnknownActiveJournal of colloid and interface science2013
Mukai M, Minamikawa H, Aoyagi M, et al.
Effect of substitution of stevioside and sucralose on rheological, spectral, color and microstructural characteristics of mango jamOther primary literatureUnknownUnknownJournal of Food Engineering.2013
Basu S, Shivhare US, Singh TV
Double emulsion stage prior to complex coacervation process for microencapsulation of sweetener sucraloseOther primary literatureUnknownUnknownJournal of Food Engineering.2013
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In vitro DNA binding studies of Aspartame, an artificial sweetener.Other primary literatureAnimalActiveJournal of photochemistry and photobiology. B, Biology2013
Kashanian S, Khodaei MM, Kheirdoosh F
Occurrence and fate of the angiotensin II receptor antagonist transformation product valsartan acid in the water cycle--a comparative study with selected β-blockers and the persistent anthropogenic wastewater indicators carbamazepine and acesulfame.Other primary literatureHumanActiveWater research2013
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Analytical methodologies for the detection of sucralose in water.Other primary literatureUnknownActiveAnalytical chemistry2013
Ferrer I, Zweigenbaum JA, Thurman EM
Re-engineering an artificial sweetener: transforming sucralose residuals in water via advanced oxidation.Other primary literatureUnknownActiveEnvironmental science & technology2013
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Polychlorinated dibenzo-p-dioxins and dibenzofurans formed from sucralose at high temperatures.Other primary literatureUnknownActiveScientific reports2013
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Sucralose, a synthetic organochlorine sweetener: overview of biological issues.ReviewHuman & animalActiveJournal of toxicology and environmental health. Part B, Critical reviews2013
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Storage Stability of Aspartame in Orange Flavored Soft DrinksOther primary literatureUnknownUnknownInternational journal of food properties2013
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Assessment of Korean consumer exposure to sodium saccharin, aspartame and stevioside.Other primary literatureHumanActiveFood additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment2013
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Effects of early intraoral acesulfame-K stimulation to mice on the adult's sweet preference and the expression of α-gustducin in fungiform papilla.Other primary literatureAnimalActiveChemical senses2013
Chen ML, Liu SS, Zhang GH, et al.
Bitterness of the non-nutritive sweetener acesulfame potassium varies with polymorphisms in TAS2R9 and TAS2R31.Other primary literatureHumanActiveChemical senses2013
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Effects of pre-exercise sucralose ingestion on carbohydrate oxidation during exercise.Randomized controlled trialHumanActiveInternational journal of sport nutrition and exercise metabolism2013
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Metabolic effects of sucralose on environmental bacteria.Other primary literatureUnknownActiveJournal of toxicology2013
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Prediabetic changes in gene expression induced by aspartame and monosodium glutamate in Trans fat-fed C57Bl/6 J mice.Other primary literatureUnknownActiveNutrition & metabolism2013
Collison KS, Makhoul NJ, Zaidi MZ, et al.
Online solid phase extraction liquid chromatography tandem mass spectrometry (SPE-LC-MS/MS) method for the determination of sucralose in reclaimed and drinking waters and its photo degradation in natural waters from South Florida.Other primary literatureUnknownActiveChemistry Central journal2013
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Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J mice.Other primary literatureHuman & animalActivePloS one2013
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Dessert formulation using sucralose and dextrin affects favorably postprandial response to glucose, insulin, and C-peptide in type 2 diabetic patients.Other primary literatureHumanActiveThe review of diabetic studies : RDS2013
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Sucralose affects glycemic and hormonal responses to an oral glucose load.Randomized controlled trialHumanActiveDiabetes care2013
Pepino MY, Tiemann CD, Patterson BW, et al.
Is sucralose ingestion acceptable before 18F-FDG PET/CT imaging?Other primary literatureHumanActiveJournal of nuclear medicine technology2013
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Long-term consumption of aspartame and brain antioxidant defense status.Other primary literatureAnimalActiveDrug and chemical toxicology2013
Abhilash M, Sauganth Paul MV, Varghese MV, et al.
Assessment of exposure of Korean consumers to acesulfame K and sucralose using a stepwise approach.Other primary literatureHumanActiveInternational journal of food sciences and nutrition2013
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Examination of the potential for adaptive chirality of the nitrogen chiral center in aza-aspartame.Other primary literatureUnknownActiveMolecules (Basel, Switzerland)2013
Bouayad-Gervais SH, Lubell WD
Effects of aspartame metabolites on astrocytes and neurons.ReviewHuman & animalActiveFolia neuropathologica2013
Rycerz K, Jaworska-Adamu JE
Carbon-deuterium rotational-echo double-resonance NMR spectroscopy of lyophilized aspartame formulations.Other primary literatureUnknownActiveJournal of pharmaceutical sciences2012
Luthra SA, Utz M, Gorman EM, et al.
Addition of sucralose enhances the release of satiety hormones in combination with pea protein.Other primary literatureHuman & animalActiveMolecular nutrition & food research2012
Geraedts MC, Troost FJ, Saris WH
Structural elucidation of main ozonation products of the artificial sweeteners cyclamate and acesulfame.Other primary literatureUnknownActiveEnvironmental science and pollution research international2012
Scheurer M, Godejohann M, Wick A, et al.
Effect of chronic exposure to aspartame on oxidative stress in the brain of albino rats.Other primary literatureAnimalActiveJournal of biosciences2012
Iyyaswamy A, Rathinasamy S
Effect of aspartame on oxidative stress and monoamine neurotransmitter levels in lipopolysaccharide-treated mice.Other primary literatureAnimalActiveNeurotoxicity research2012
Abdel-Salam OM, Salem NA, Hussein JS
Sucralose - an ecotoxicological challenger?Other primary literatureAnimalActiveChemosphere2012
Wiklund AK, Breitholtz M, Bengtsson BE, et al.
Kinetics of the oxidation of sucralose and related carbohydrates by ferrate(VI).Other primary literatureUnknownActiveChemosphere2012
Sharma VK, Sohn M, Anquandah GA, et al.
Stability considerations of aspartame in the direct analysis of artificial sweeteners in water samples using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).Other primary literatureUnknownActiveChemosphere2012
Berset JD, Ochsenbein N
Synthesis of galactosyl sucralose by β-galactosidase from Lactobacillus bulgaricus L3Other primary literatureUnknownUnknownFood chemistry2012
Lü L, Xu S, Jin L, et al.
Rheological, textural and sensorial properties of low-sucrose muffins reformulated with sucralose/polydextroseOther primary literatureUnknownUnknownLWT.2012
Martínez-Cervera S, Sanz T, Salvador A, et al.
Presence, fate and effects of the intense sweetener sucralose in the aquatic environment.ReviewAnimalActiveThe Science of the total environment2012
Tollefsen KE, Nizzetto L, Huggett DB
Differentiating sources of anthropogenic loading to impaired water bodies utilizing ratios of sucralose and other microconstituents.Other primary literatureUnknownActiveWater research2012
Oppenheimer JA, Badruzzaman M, Jacangelo JG
Sucralose revisited: rebuttal of two papers about Splenda safety.Other primary literatureHuman & animalActiveRegulatory toxicology and pharmacology : RTP2012
Schiffman SS, Abou-Donia MB
Evaluation and comparison of antinociceptive activity of aspartame with sucrose.Other primary literatureAnimalActivePharmacological reports : PR2012
Rani S, Gupta MC
GUT bacteria and aspartame: why are we surprised?Other primary literatureHumanActiveEuropean journal of clinical nutrition2012
Pretorius E
Preference for sucralose predicts behavioral responses to sweet and bittersweet tastants.Other primary literatureAnimalActiveChemical senses2012
Loney GC, Torregrossa AM, Carballo C, et al.
Formulation optimisation of a whey lemon beverage using a blend of the sweeteners aspartame and saccharinOther primary literatureUnknownUnknownInternational Journal of Dairy Technology2012
MEENA MK, ARORA S, SHENDURSE AM, et al.
Systemic allergic dermatitis presumably caused by formaldehyde derived from aspartame.Other primary literatureHumanActiveContact dermatitis2012
Veien NK, Lomholt HB
Aspartame in conjunction with carbohydrate reduces insulin levels during endurance exercise.Other primary literatureUnknownActiveJournal of the International Society of Sports Nutrition2012
Siegler J, Howell K, Vince R, et al.
Interactive effects of neonatal exposure to monosodium glutamate and aspartame on glucose homeostasis.Other primary literatureUnknownActiveNutrition & metabolism2012
Collison KS, Makhoul NJ, Zaidi MZ, et al.
Gender dimorphism in aspartame-induced impairment of spatial cognition and insulin sensitivity.Other primary literatureAnimalActivePloS one2012
Collison KS, Makhoul NJ, Zaidi MZ, et al.
Cytotoxic effect of aspartame (diet sweet) on the histological and genetic structures of female albino rats and their offspring.Other primary literatureAnimalActivePakistan journal of biological sciences : PJBS2012
Abd Elfatah AA, Ghaly IS, Hanafy SM
Soft drinks, aspartame, and the risk of cancer and cardiovascular disease.Other primary literatureHumanActiveThe American journal of clinical nutrition2012
Aune D
[Simultaneous determination of aspartame and alitame in jellies and preserved fruits by HPLC].Other primary literatureUnknownActiveWei sheng yan jiu = Journal of hygiene research2012
Jiang D, Fang C, Yang D
Studies on the effects of aspartame on memory and oxidative stress in brain of mice.Other primary literatureAnimalActiveEuropean review for medical and pharmacological sciences2012
Abdel-Salam OM, Salem NA, El-Shamarka ME, et al.
Kinetic spectrophotometric methods for the determination of artificial sweetener (sucralose) in tablets.Other primary literatureUnknownActiveDrug testing and analysis2011
Youssef RM, Korany MA, Khamis EF, et al.
Bioconcentration of the intense sweetener sucralose in a multitrophic battery of aquatic organisms.Other primary literatureAnimalActiveEnvironmental toxicology and chemistry2011
Lillicrap A, Langford K, Tollefsen KE
What caused the recent worldwide increase of inflammatory bowel disease: should sucralose be added as a suspect?Other primary literatureHumanActiveInflammatory bowel diseases2011
Qin X
Sucralose sweetener in vivo effects on blood constituents radiolabeling, red blood cell morphology and radiopharmaceutical biodistribution in rats.Other primary literatureAnimalActiveApplied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine2011
Rocha GS, Pereira MO, Benarroz MO, et al.
Development of a quantitative high-performance thin-layer chromatographic method for sucralose in sewage effluent, surface water, and drinking water.Other primary literatureUnknownActiveJournal of chromatography. A2011
Morlock GE, Schuele L, Grashorn S
Simultaneous analysis of aspartame and its hydrolysis products of Coca-Cola Zero by on-line postcolumn derivation fluorescence detection and ultraviolet detection coupled two-dimensional high-performance liquid chromatography.Other primary literatureUnknownActiveJournal of chromatography. A2011
Cheng C, Wu SC
Identification of perfluoroalkyl acid sources in Swiss surface waters with the help of the artificial sweetener acesulfame.Other primary literatureUnknownActiveEnvironmental pollution (Barking, Essex : 1987)2011
Müller CE, Gerecke AC, Alder AC, et al.
Cob(I)alamin reacts with sucralose to afford an alkylcobalamin: relevance to in vivo cobalamin and sucralose interaction.Other primary literatureHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2011
Motwani HV, Qiu S, Golding BT, et al.
Effect of long term intake of aspartame on antioxidant defense status in liver.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2011
Abhilash M, Paul MV, Varghese MV, et al.
Effects of the artificial sweetener sucralose on Daphnia magna and Americamysis bahia survival, growth and reproduction.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2011
Huggett DB, Stoddard KI
Aspartame-fed zebrafish exhibit acute deaths with swimming defects and saccharin-fed zebrafish have elevation of cholesteryl ester transfer protein activity in hypercholesterolemia.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2011
Kim JY, Seo J, Cho KH
Simultaneous determination of aspartame, cyclamate, saccharin and acesulfame-K in soft drinks and tabletop sweetener formulations by capillary electrophoresis with capacitively coupled contactless conductivity detectionOther primary literatureUnknownUnknownFood chemistry2011
Bergamo AB, Fracassi da Silva JA, de Jesus DP
Quantification of aspartame in commercial sweeteners by FT-Raman spectroscopyOther primary literatureUnknownUnknownFood chemistry2011
Mazurek S, Szostak R
Sweetness intensity perception and pleasantness ratings of sucrose, aspartame solutions and cola among multi-ethnic Malaysian subjectsOther primary literatureUnknownUnknownFood Quality and Preference.2011
Thai PK, Tan EC, Tan WL, et al.
Neonatal exposure to sucralose does not alter biochemical markers of neuronal development or adult behavior.Other primary literatureAnimalActiveNutrition (Burbank, Los Angeles County, Calif.)2011
Viberg H, Fredriksson A
Short-term consumption of sucralose, a nonnutritive sweetener, is similar to water with regard to select markers of hunger signaling and short-term glucose homeostasis in women.Other primary literatureHumanActiveNutrition research (New York, N.Y.)2011
Brown AW, Bohan Brown MM, Onken KL, et al.
In vitro effect of aspartame in angiogenesis induction.Other primary literatureHumanActiveToxicology in vitro : an international journal published in association with BIBRA2011
Alleva R, Borghi B, Santarelli L, et al.
Oxalate and sucralose absorption in idiopathic calcium oxalate stone formers.Other primary literatureHumanActiveUrology2011
Knight J, Jiang J, Wood KD, et al.
Occurrence and suitability of sucralose as an indicator compound of wastewater loading to surface waters in urbanized regions.Other primary literatureUnknownActiveWater research2011
Oppenheimer J, Eaton A, Badruzzaman M, et al.
Fate of sucralose through environmental and water treatment processes and impact on plant indicator species.Other primary literatureUnknownActiveEnvironmental science & technology2011
Soh L, Connors KA, Brooks BW, et al.
Artificial sweetener sucralose in U.S. drinking water systems.Other primary literatureUnknownActiveEnvironmental science & technology2011
Mawhinney DB, Young RB, Vanderford BJ, et al.
Effects of oral ingestion of sucralose on gut hormone response and appetite in healthy normal-weight subjects.Randomized controlled trialHumanActiveEuropean journal of clinical nutrition2011
Ford HE, Peters V, Martin NM, et al.
Sweet taste receptor gene variation and aspartame taste in primates and other species.Other primary literatureHuman & animalActiveChemical senses2011
Li X, Bachmanov AA, Maehashi K, et al.
Rats display a robust bimodal preference profile for sucralose.Other primary literatureAnimalActiveChemical senses2011
Loney GC, Torregrossa AM, Smith JC, et al.
Effects of mother's dietary exposure to acesulfame-K in Pregnancy or lactation on the adult offspring's sweet preference.Other primary literatureAnimalActiveChemical senses2011
Zhang GH, Chen ML, Liu SS, et al.
Pilot study: alleviation of pain in burning mouth syndrome with topical sucralose.Other primary literatureHumanActiveHeadache2011
Hirsch AR, Ziad A, Kim AY, et al.
What made Canada become a country with the highest incidence of inflammatory bowel disease: could sucralose be the culprit?Other primary literatureHumanActiveCanadian journal of gastroenterology = Journal canadien de gastroenterologie2011
Qin X
[When will be the prohibition of sugar and aspartame?].Other primary literatureHumanActiveRevue medicale suisse2011
Nau JY
Aspartame administered in feed, beginning prenatally through life span, induces cancers of the liver and lung in male Swiss mice.Other primary literatureAnimalActiveAmerican journal of industrial medicine2010
Soffritti M, Belpoggi F, Manservigi M, et al.
Facilitation of the development of fungiform taste buds by early intraoral acesulfame-K stimulation to mice.Other primary literatureAnimalActiveJournal of neural transmission (Vienna, Austria : 1996)2010
Zhang GH, Chen ML, Liu SS, et al.
Effects of stevia, aspartame, and sucrose on food intake, satiety, and postprandial glucose and insulin levels.Other primary literatureHumanActiveAppetite2010
Anton SD, Martin CK, Han H, et al.
Analysis of sucralose and other sweeteners in water and beverage samples by liquid chromatography/time-of-flight mass spectrometry.Other primary literatureUnknownActiveJournal of chromatography. A2010
Ferrer I, Thurman EM
The absence of genotoxicity of sucralose.Other primary literatureHuman & animalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2010
Brusick D, Grotz VL, Slesinski R, et al.
Thermal degradation of sucralose and its potential in generating chloropropanols in the presence of glycerolOther primary literatureUnknownUnknownFood chemistry2010
Rahn A, Yaylayan VA
Pt(II) and Ag(I) complexes with acesulfame: crystal structure and a study of their antitumoral, antimicrobial and antiviral activities.Other primary literatureHumanActiveJournal of inorganic biochemistry2010
Cavicchioli M, Massabni AC, Heinrich TA, et al.
Understanding consumption-related sucralose emissions - A conceptual approach combining substance-flow analysis with sampling analysis.Other primary literatureUnknownActiveThe Science of the total environment2010
Neset TS, Singer H, Longrée P, et al.
Effect of the artificial sweetener, sucralose, on small intestinal glucose absorption in healthy human subjects.Other primary literatureHumanActiveThe British journal of nutrition2010
Ma J, Chang J, Checklin HL, et al.
Polymorphism in acesulfame sweetener: structure-property and stability relationships of bending and brittle crystals.Other primary literatureUnknownActiveChemical communications (Cambridge, England)2010
Velaga SP, Vangala VR, Basavoju S, et al.
Enhancement of the aspartame precursor synthetic activity of an organic solvent-stable protease.Other primary literatureUnknownActiveProtein engineering, design & selection : PEDS2010
Ogino H, Tsuchiyama S, Yasuda M, et al.
Use of aspartame-based sweetener tablets in emergency dosimetry using EPR.Other primary literatureUnknownActiveRadiation protection dosimetry2010
Maghraby A, Salama E
The development of burfi sweetened with aspartameOther primary literatureUnknownUnknownInternational Journal of Dairy Technology2010
ARORA S, GAWANDE H, BALBIR KAUR WADHWA VS, et al.
Application of agonist-receptor modeling to the sweetness synergy between high fructose corn syrup and sucralose, and between high-potency sweeteners.Other primary literatureHumanActiveJournal of food science2010
Wolf PA, Bridges JR, Wicklund R
Gastric bypass surgery alters behavioral and neural taste functions for sweet taste in obese rats.Other primary literatureAnimalActiveAmerican journal of physiology. Gastrointestinal and liver physiology2010
Hajnal A, Kovacs P, Ahmed T, et al.
In vivo cytogenetic studies on aspartame.Other primary literatureUnknownActiveComparative and functional genomics2010
Alsuhaibani ES
Inadequate toxicity tests of food additive acesulfame.Other primary literatureHuman & animalCorrectedInternational journal of occupational and environmental health2010
Karstadt M
Aspartame-acesulfame k-containing low-energy erythritol sweetener markedly suppresses postprandial hyperglycemia in mild and borderline diabeticsOther primary literatureUnknownUnknownFood science and technology research2010
Fukuda M, Terata T, Tsuda K, et al.
Aspartame--facts and fiction.Other primary literatureHuman & animalActiveThe New Zealand medical journal2010
Magnuson B
Aspartame-induced fibromyalgia, an unusual but curable cause of chronic pain.Other primary literatureHumanActiveClinical and experimental rheumatology2010
Ciappuccini R, Ansemant T, Maillefert JF, et al.
Hunger and negative alliesthesia to aspartame and sucrose in patients treated with antipsychotic drugs and controls.Randomized controlled trialHumanActiveEating and weight disorders : EWD2009
Khazaal Y, Chatton A, Claeys F, et al.
Comparison of thermochemistry of aspartame (artificial sweetener) and glucose.Other primary literatureUnknownActiveCarbohydrate research2009
Rashidian M, Fattahi A
Sucralose screening in European surface waters using a solid-phase extraction-liquid chromatography-triple quadrupole mass spectrometry method.Other primary literatureHumanActiveJournal of chromatography. A2009
Loos R, Gawlik BM, Boettcher K, et al.
Simultaneous determination of aspartame and acesulfame-K by molecular absorption spectrophotometry using multivariate calibration and validation by high performance liquid chromatographyOther primary literatureUnknownUnknownFood chemistry2009
Cantarelli MA, Pellerano RG, Marchevsky EJ, et al.
'Lone' atrial fibrillation precipitated by monosodium glutamate and aspartame.Other primary literatureHumanActiveInternational journal of cardiology2009
Burkhart CG
Characterization of aspartame-cyclodextrin complexation.Other primary literatureUnknownActiveJournal of pharmaceutical and biomedical analysis2009
Sohajda T, Béni S, Varga E, et al.
An overview of the safety of sucralose.ReviewHuman & animalActiveRegulatory toxicology and pharmacology : RTP2009
Grotz VL, Munro IC
Ubiquitous occurrence of the artificial sweetener acesulfame in the aquatic environment: an ideal chemical marker of domestic wastewater in groundwater.Other primary literatureUnknownActiveEnvironmental science & technology2009
Buerge IJ, Buser HR, Kahle M, et al.
Aspartame effects on the brain.Other primary literatureHuman & animalActiveEuropean journal of clinical nutrition2009
Fernstrom JD
Consumption of SC45647 and sucralose by rats selectively bred for high and low saccharin intake.Other primary literatureAnimalActiveChemical senses2009
Dess NK, Chapman CD, Monroe D
Determination of sucralose in soft drinks by high-performance thin-layer chromatography: interlaboratory study.Other primary literatureUnknownActiveJournal of AOAC International2009
Stroka J, Doncheva I, Spangenberg B
Perspective on aspartame-induced pseudotumor cerebri.Other primary literatureHumanActiveSouthern medical journal2009
Roberts HJ
Kinetics of an acid-base catalyzed reaction (aspartame degradation) as affected by polyol-induced changes in buffer pH and pK values.Other primary literatureUnknownActiveJournal of food science2009
Chuy S, Bell LN
Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects.Randomized controlled trialHumanActiveAmerican journal of physiology. Gastrointestinal and liver physiology2009
Ma J, Bellon M, Wishart JM, et al.
Formaldehyde, aspartame, migraines: a possible connection.Other primary literatureHumanActiveDermatitis : contact, atopic, occupational, drug2009
Abegaz EG, Bursey RG
Vestibulocochlear toxicity in a pair of siblings 15 years apart secondary to aspartame: two case reports.Other primary literatureUnknownActiveCases journal2009
Pisarik P, Kai D
[Effect of aspartame on the liver cirrhosis model induced by the complex factors].Other primary literatureAnimalActiveZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2009
Ding XC, Ma LN, Chen XX
Sweetening ruthenium and osmium: organometallic arene complexes containing aspartame.Other primary literatureHumanActiveJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2008
Gray JC, Habtemariam A, Winnig M, et al.
Formaldehyde adduct to human serum albumin with reference to aspartame intake.Other primary literatureUnknownActiveEnvironmental toxicology and pharmacology2008
Gilli G, Schilirò T, Traversi D, et al.
Re: The effect of aspartame metabolites on the suckling rat frontal cortex acetylcholinesterase. An in vitro study.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2008
Renwick AG
l-Cysteine and glutathione restore the modulation of rat frontal cortex Na+, K+ -ATPase activity induced by aspartame metabolites.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2008
Simintzi I, Schulpis KH, Angelogianni P, et al.
The hydration/dehydration behavior of aspartame revisited.Other primary literatureUnknownActiveJournal of pharmaceutical and biomedical analysis2008
Guguta C, Meekes H, de Gelder R
Response to "the effect of aspartame on the acetylcholinesterase activity in hippocampal homogenates of suckling rats" by Simintzi et al.Other primary literatureAnimalActivePharmacological research2008
Abegaz EG, Bursey RG
Simultaneous square-wave voltammetric determination of aspartame and cyclamate using a boron-doped diamond electrode.Other primary literatureUnknownActiveTalanta2008
Medeiros RA, de Carvalho AE, Rocha-Filho RC, et al.
Application of multibounce attenuated total reflectance fourier transform infrared spectroscopy and chemometrics for determination of aspartame in soft drinks.Other primary literatureUnknownActiveJournal of agricultural and food chemistry2008
Khurana HK, Cho IK, Shim JY, et al.
Simultaneous determination of saccharin and aspartame in commercial noncaloric sweeteners using the PLS-2 multivariate calibration method and validation by capillary electrophoresis.Other primary literatureUnknownActiveJournal of agricultural and food chemistry2008
Cantarelli MA, Pellerano RG, Marchevsky EJ, et al.
Direct and indirect cellular effects of aspartame on the brain.ReviewHumanActiveEuropean journal of clinical nutrition2008
Humphries P, Pretorius E, Naudé H
Genotoxicity testing of low-calorie sweeteners: aspartame, acesulfame-K, and saccharin.Other primary literatureAnimalActiveDrug and chemical toxicology2008
Bandyopadhyay A, Ghoshal S, Mukherjee A
Estimated intake of the sweeteners, acesulfame-K and aspartame, from soft drinks, soft drinks based on mineral waters and nectars for a group of Portuguese teenage students.Other primary literatureHumanActiveFood additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment2008
Lino CM, Costa IM, Pena A, et al.
Overlooked aspartame-induced hypertension.Other primary literatureHumanActiveSouthern medical journal2008
Roberts HJ
Sucralose and migraine.Other primary literatureHumanActiveHeadache2008
Grotz VL
Attenuated total reflectance-Fourier transform infrared spectroscopy coupled with multivariate analysis for measurement of acesulfame-K in diet foods.Other primary literatureHumanActiveJournal of food science2008
Shim JY, Cho IK, Khurana HK, et al.
Aspartame and incidence of brain malignancies.Other primary literatureHumanActiveCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2008
Davis DL, Ganter L, Weinkle J
Carcinogenicity of aspartame in rats not proven.Other primary literatureAnimalActiveEnvironmental health perspectives2008
Magnuson B, Williams GM
[Simultaneous determination of neotame, alitame and aspartame in foods by HPLC].Other primary literatureUnknownActiveShokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan2008
Matsumoto H, Hirata K, Sakamaki N, et al.
Formaldehyde, aspartame, and migraines: a possible connection.Other primary literatureHumanActiveDermatitis : contact, atopic, occupational, drug2008
Jacob SE, Stechschulte S
Synthesis, characterization and antimycobacterial activity of Ag(I)-aspartame, Ag(I)-saccharin and Ag(I)-cyclamate complexes.Other primary literatureHumanActiveArchiv der Pharmazie2007
Cavicchioli M, Leite CQ, Sato DN, et al.
A facile HPLC method for optical purity and quantitative measurements of phenylalanine from the hydrolyzed aspartame under different pH and temperature after its derivatization with a fluorescent reagent.Other primary literatureUnknownActiveAmino acids2007
Hsien TJ, Chen S
Safety and efficacy of aspartame-based liquid versus sucrose-based liquids used for dilution in oral sodium phosphate solutions for colonoscopy preparations.Randomized controlled trialHumanActiveDigestive diseases and sciences2007
Chamberlain SM, Balart JC, Sideridis K, et al.
Aspartame demand in rhesus monkeys: effects of volume and concentration manipulations.Other primary literatureAnimalActiveBehavioural processes2007
Wade-Galuska T, Galuska CM, Winger G, et al.
First European conference on aspartame: putting safety and benefits into perspective. Synopsis of presentations and conclusions.Design not determinedHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2007
Renwick AG, Nordmann H
The effect of aspartame metabolites on the suckling rat frontal cortex acetylcholinesterase. An in vitro study.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2007
Simintzi I, Schulpis KH, Angelogianni P, et al.
Aspartame decreases evoked extracellular dopamine levels in the rat brain: an in vivo voltammetry study.Other primary literatureAnimalActiveNeuropharmacology2007
Bergstrom BP, Cummings DR, Skaggs TA
The effect of aspartame on acetylcholinesterase activity in hippocampal homogenates of suckling rats.Other primary literatureAnimalActivePharmacological research2007
Simintzi I, Schulpis KH, Angelogianni P, et al.
L-Cysteine and glutathione restore the reduction of rat hippocampal Na+, K+-ATPase activity induced by aspartame metabolites.Other primary literatureAnimalActiveToxicology2007
Simintzi I, Schulpis KH, Angelogianni P, et al.
Peptide synthesis of aspartame precursor using organic-solvent-stable PST-01 protease in monophasic aqueous-organic solvent systems.Other primary literatureUnknownActiveBiotechnology progress2007
Tsuchiyama S, Doukyu N, Yasuda M, et al.
Analysis and stability of sucralose in a milk-based confection by a simple planar chromatographic method.Other primary literatureAnimalActiveJournal of agricultural and food chemistry2007
Morlock GE, Prabha S
Ultrastructural changes to rabbit fibrin and platelets due to aspartame.Other primary literatureAnimalActiveUltrastructural pathology2007
Pretorius E, Humphries P
Aspartame: a safety evaluation based on current use levels, regulations, and toxicological and epidemiological studies.ReviewHuman & animalActiveCritical reviews in toxicology2007
Magnuson BA, Burdock GA, Doull J, et al.
Aspartame-induced thrombocytopenia.Other primary literatureHumanActiveSouthern medical journal2007
Roberts HJ
Migraine triggered by sucralose--a case report.Other primary literatureHumanActiveHeadache2007
Hirsch AR
Oxytocin knockout mice demonstrate enhanced intake of sweet and nonsweet carbohydrate solutions.Other primary literatureAnimalActiveAmerican journal of physiology. Regulatory, integrative and comparative physiology2007
Sclafani A, Rinaman L, Vollmer RR, et al.
Aspartame consumption and incidence of hematopoietic and brain cancers.Other primary literatureHumanActiveCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2007
Samuels A
Aspartame bioassay findings portend human cancer hazards.Other primary literatureHuman & animalActiveInternational journal of occupational and environmental health2007
Huff J, LaDou J
Letter to U.S. FDA commissioner. Questions about the safety of the artificial sweetener aspartame.Other primary literatureHuman & animalActiveInternational journal of occupational and environmental health2007
Abdo KM, Camargo CA Jr, Davis D, et al.
Life-span exposure to low doses of aspartame beginning during prenatal life increases cancer effects in rats.Other primary literatureAnimalActiveEnvironmental health perspectives2007
Soffritti M, Belpoggi F, Tibaldi E, et al.
Aspartame not linked to cancer.Other primary literatureAnimalActiveEnvironmental health perspectives2007
Abegaz EG
Is aspartame really safer in reducing the risk of hypoglycemia during exercise in patients with type 2 diabetes?Other primary literatureHumanActiveDiabetes care2007
Ferland A, Brassard P, Poirier P
The effect of aspartame administration on oncogene and suppressor gene expressions.Other primary literatureAnimalCorrectedIn vivo (Athens, Greece)2007
Gombos K, Varjas T, Orsós Z, et al.
Conformation analysis of aspartame-based sweeteners by NMR spectroscopy, molecular dynamics simulations, and X-ray diffraction studies.Other primary literatureUnknownActiveChembiochem : a European journal of chemical biology2006
De Capua A, Goodman M, Amino Y, et al.
Resolution of an intense sweetener mixture by use of a flow injection sensor with on-line solid-phase extraction. Application to saccharin and aspartame in sweets and drinks.Other primary literatureUnknownActiveAnalytical and bioanalytical chemistry2006
Capitán-Vallvey LF, Valencia MC, Arana Nicolás E, et al.
Renewable stationary phase liquid magnetochromatography: determining aspartame and its hydrolysis products in diet soft drinks.Other primary literatureUnknownActiveAnalytical and bioanalytical chemistry2006
Barrado E, Rodríguez JA, Castrillejo Y
Viability of human-derived probiotic lactobacilli in ice cream produced with sucrose and aspartame.Other primary literatureHumanActiveJournal of industrial microbiology & biotechnology2006
Başyiğit G, Kuleaşan H, Karahan AG
A biosensor based on graphite epoxy composite electrode for aspartame and ethanol detection.Other primary literatureUnknownActiveAnalytica chimica acta2006
Kirgöz UA, Odaci D, Timur S, et al.
A material-sparing method for simultaneous determination of true density and powder compaction properties--aspartame as an example.Other primary literatureUnknownActiveInternational journal of pharmaceutics2006
Sun CC
The effect of aspartame metabolites on human erythrocyte membrane acetylcholinesterase activity.Other primary literatureHumanActivePharmacological research2006
Tsakiris S, Giannoulia-Karantana A, Simintzi I, et al.
The effect of L-cysteine and glutathione on inhibition of Na+, K+-ATPase activity by aspartame metabolites in human erythrocyte membrane.Other primary literatureHumanActiveEuropean journal of clinical nutrition2006
Schulpis KH, Papassotiriou I, Parthimos T, et al.
Aspartame-induced Sjögren syndrome.Other primary literatureHumanActiveSouthern medical journal2006
Robert HJ
Effect of addition of sucrose and aspartame on the compression resistance of hydrocolloids gelsOther primary literatureUnknownUnknownInternational journal of food science & technology2006
Bayarri S, Izquierdo L, Durán L, et al.
Sugarcane ShSUT1: analysis of sucrose transport activity and inhibition by sucralose.Other primary literatureAnimalActivePlant, cell & environment2006
Reinders A, Sivitz AB, Hsi A, et al.
Migraine triggered by sucralose--a case report.Other primary literatureHumanActiveHeadache2006
Bigal ME, Krymchantowski AV
Popular sweetner sucralose as a migraine trigger.Other primary literatureHumanActiveHeadache2006
Patel RM, Sarma R, Grimsley E
Consumption of aspartame-containing beverages and incidence of hematopoietic and brain malignancies.Other primary literatureHumanActiveCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2006
Lim U, Subar AF, Mouw T, et al.
The effect of aspartame on rat brain xenobiotic-metabolizing enzymes.Other primary literatureAnimalActiveHuman & experimental toxicology2006
Vences-Mejía A, Labra-Ruíz N, Hernández-Martínez N, et al.
Results of long-term carcinogenicity bioassay on Sprague-Dawley rats exposed to aspartame administered in feed.Other primary literatureAnimalActiveAnnals of the New York Academy of Sciences2006
Belpoggi F, Soffritti M, Padovani M, et al.
Testing needed for acesulfame potassium, an artificial sweetener.Other primary literatureHuman & animalActiveEnvironmental health perspectives2006
Karstadt ML
First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley rats.Other primary literatureAnimalActiveEnvironmental health perspectives2006
Soffritti M, Belpoggi F, Degli Esposti D, et al.
A review of the effectiveness of aspartame in helping with weight controlOther primary literatureUnknownUnknownNutrition Bulletin.2006
de la Hunty A, Gibson S, Ashwell M
[Sweetening agent aspartame as carcinogen?].Other primary literatureAnimalActiveKinderkrankenschwester : Organ der Sektion Kinderkrankenpflege2006
Experimental design-based development and single laboratory validation of a capillary zone electrophoresis method for the determination of the artificial sweetener sucralose in food matrices.Other primary literatureUnknownActiveAnalytical and bioanalytical chemistry2005
McCourt J, Stroka J, Anklam E
Male rats show an indifference-avoidance response for increasing concentrations of the artificial sweetener sucralose.Other primary literatureUnknownActiveNutrition research (New York, N.Y.)2005
Bello NT, Hajnal A
Daily intake assessment of saccharin, stevioside, D-sorbitol and aspartame from various processed foods in Korea.Other primary literatureHumanActiveFood additives and contaminants2005
Chung MS, Suh HJ, Yoo W, et al.
Qualities of chiffon cake prepared with indigestible dextrin and sucralose as replacement for sucroseOther primary literatureUnknownUnknownCereal chemistry2005
Lin SD, Lee CC
Aspartame and its effects on health: independently funded studies have found potential for adverse effects.Other primary literatureHumanActiveBMJ (Clinical research ed.)2005
Briffa J
Aspartame and its effects on health: readers may prefer balanced and impartial editorials.Other primary literatureHumanActiveBMJ (Clinical research ed.)2005
Gordon IJ
Aspartame and its effects on health: approach seems simplistic in electronic responses to editorial.Other primary literatureHumanActiveBMJ (Clinical research ed.)2005
Finer N
A simple method for the analysis of urinary sucralose for use in tests of intestinal permeability.Other primary literatureHumanActiveAnnals of clinical biochemistry2005
Anderson AD, Poon P, Greenway GM, et al.
Possible analgesic and anti-inflammatory interactions of aspartame with opioids and NSAIDs.Other primary literatureAnimalActiveIndian journal of experimental biology2005
Sharma S, Jain NK, Kulkarni SK
NTP report on the toxicology studies of aspartame (CAS No. 22839-47-0) in genetically modified (FVB Tg.AC hemizygous) and B6.129-Cdkn2atm1Rdp (N2) deficient mice and carcinogenicity studies of aspartame in genetically modified [B6.129-Trp53tm1Brd (N5) haploinsufficient] mice (feed studies).Other primary literatureAnimalActiveNational Toxicology Program genetically modified model report2005
NTP toxicology studies of acesulfame potassium (CAS No. 55589-62-3) in genetically modified (FVB Tg.AC Hemizygous) mice and carcinogenicity studies of acesulfame potassium in genetically modified [B6.129-Trp53(tm1Brd) (N5) Haploinsufficient] mice (feed studies)mice.Other primary literatureAnimalActiveNational Toxicology Program genetically modified model report2005
Aspartame and aspartame derivatives effect human thrombin catalytic activity.Other primary literatureHumanActiveBiophysical chemistry2004
Scheffler JE, Berliner LJ
Aspartame has no effect on the polymerization of sickle hemoglobin.Other primary literatureUnknownActiveClinical pharmacology and therapeutics2004
Rotter MA, Aprelev A, Dragos D, et al.
Chronic aspartame affects T-maze performance, brain cholinergic receptors and Na+,K+-ATPase in rats.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior2004
Christian B, McConnaughey K, Bethea E, et al.
FTIR determination of Aspartame and Acesulfame-K in tabletop sweeteners.Other primary literatureUnknownActiveJournal of agricultural and food chemistry2004
Armenta S, Garrigues S, de la Guardia M
Determination of sucralose in Splenda and a sugar-free beverage using high-performance anion-exchange chromatography with pulsed amperometric detection.Other primary literatureUnknownActiveJournal of agricultural and food chemistry2004
Hanko VP, Rohrer JS
Genotoxicity of aspartame.Other primary literatureAnimalActiveDrug and chemical toxicology2004
Rencüzoğullari E, Tüylü BA, Topaktaş M, et al.
Synthesis and characteristics of an aspartame analogue, L-asparaginyl L-3-phenyllactic acid methyl ester.Other primary literatureUnknownActiveActa biochimica et biophysica Sinica2004
Tao H, Cui DF, Zhang YS
Female rats show a bimodal preference response to the artificial sweetener sucralose.Other primary literatureAnimalActiveChemical senses2004
Sclafani A, Clare RA
A novel strategy for selection of allosteric ribozymes yields RiboReporter sensors for caffeine and aspartame.Other primary literatureUnknownActiveNucleic acids research2004
Ferguson A, Boomer RM, Kurz M, et al.
Aspartame and its effects on health.Other primary literatureHumanActiveBMJ (Clinical research ed.)2004
Lean ME, Hankey CR
Bitter taste receptors for saccharin and acesulfame K.Other primary literatureHumanActiveThe Journal of neuroscience : the official journal of the Society for Neuroscience2004
Kuhn C, Bufe B, Winnig M, et al.
Flow-through spectrophotometric sensor for the determination of aspartame in low-calorie and dietary products.Other primary literatureUnknownActiveAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2004
Capitán-Vallvey LF, Valencia MC, Nicolás EA
Evaluation of a possible proximity effect of aspartame and vitamin C on muscular strength.Other primary literatureHumanActivePerceptual and motor skills2004
Keating TM, Kendler BS, Merriman W
Synthesis and Characteristics of an Aspartame Analogue, L-Asparaginyl L-3-Phenyllactic Acid Methyl EsterDesign not determinedUnknownUnknownSheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica2004
Tao Hu, Cui Dafu, Zhang Youshang
Aspartame disease: a possible cause for concomitant Graves' disease and pulmonary hypertension.Other primary literatureHumanActiveTexas Heart Institute journal2004
Roberts HJ
[Adverse effect of aspartame--does it exist?].Other primary literatureHumanActiveLakartidningen2004
Svederberg S
Effect of aspartame on circadian oscillations of calcium and inorganic phosphorus in rats.Other primary literatureAnimalActiveIndian journal of biochemistry & biophysics2004
Rajasekar P, Manivasagam T, Subramanian P
Lack of effect of sucralose on glucose homeostasis in subjects with type 2 diabetes.Randomized controlled trialHumanActiveJournal of the American Dietetic Association2003
Grotz VL, Henry RR, McGill JB, et al.
Electrochemical study of the complexes of aspartame with Cu(II), Ni(II) and Zn(II) ions in the aqueous medium.Other primary literatureUnknownActiveCarbohydrate research2003
Cakir S, Coskun E, Biçer E, et al.
Physiological mechanisms mediating aspartame-induced satiety.Other primary literatureHumanActivePhysiology & behavior2003
Hall WL, Millward DJ, Rogers PJ, et al.
Application of an effective diffusion model to the adsorption of Aspartame on functionalised divinylbenzene-styrene macroporous resinsOther primary literatureUnknownUnknownJournal of Food Engineering.2003
Bautista LF, Plata MM, Aracil J, et al.
A comparison of aspartame and sucrose with respect to carryover effects in yogurtOther primary literatureUnknownUnknownFood Quality and Preference.2003
King BM, Arents P, Duineveld CAA
Gas chromatographic method for detection of urinary sucralose: application to the assessment of intestinal permeability.Other primary literatureHumanActiveJournal of chromatography. B, Analytical technologies in the biomedical and life sciences2003
Farhadi A, Keshavarzian A, Holmes EW, et al.
Construction of hybrid peptide synthetases for the production of alpha-l-aspartyl-l-phenylalanine, a precursor for the high-intensity sweetener aspartame.Other primary literatureUnknownActiveEuropean journal of biochemistry2003
Duerfahrt T, Doekel S, Sonke T, et al.
Estimated intake of the artificial sweeteners acesulfame-K, aspartame, cyclamate and saccharin in a group of Swedish diabetics.Other primary literatureHumanActiveFood additives and contaminants2003
Ilbäck NG, Alzin M, Jahrl S, et al.
Headspace solid-phase micro-extraction gas chromatography method for the determination of methanol in aspartame sweeteners.Other primary literatureHumanActiveFood additives and contaminants2003
Sales JA, de Lourdes Cardeal Z
Determination of the artificial sweetener Sucralose by capillary electrophoresis.Other primary literatureHumanActiveFood additives and contaminants2003
Stroka J, Dossi N, Anklam E
Determination of acesulfame and sucralose in oral electrolyte maintenance solution by liquid chromatography.Other primary literatureUnknownActiveJournal of AOAC International2003
Johns P, Dowlati L
Systemic contact dermatitis of the eyelids caused by formaldehyde derived from aspartame?Other primary literatureHumanActiveContact dermatitis2003
Hill AM, Belsito DV
Wants to clear up Internet misinformation regarding aspartame.Other primary literatureAnimalActiveJournal of the American Veterinary Medical Association2003
Carakostas M
[Controversies with aspartame].Other primary literatureHuman & animalActiveMedicinski pregled2003
Janković SM
Aspartame: review of safety.ReviewHuman & animalActiveRegulatory toxicology and pharmacology : RTP2002
Butchko HH, Stargel WW, Comer CP, et al.
Effects of long-term ingestion of aspartame on hypothalamic neuropeptide Y, plasma leptin and body weight gain and composition.Other primary literatureAnimalActivePhysiology & behavior2002
Beck B, Burlet A, Max JP, et al.
Aspartame optical biosensor with bienzyme-immobilized eggshell membrane and oxygen-sensitive optode membrane.Other primary literatureAnimalActiveAnalytical chemistry2002
Xiao D, Choi MM
Cytotoxic effects of methanol, formaldehyde, and formate on dissociated rat thymocytes: a possibility of aspartame toxicity.Other primary literatureAnimalActiveCell biology and toxicology2002
Oyama Y, Sakai H, Arata T, et al.
Bitter taste of saccharin and acesulfame-K.Other primary literatureHumanActiveChemical senses2002
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Modified DNA aptamers against sweet agent aspartame.Other primary literatureUnknownActiveNucleic acids research. Supplement (2001)2002
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[Determination of sucralose in foods by liquid chromatography/tandem mass spectrometry].Other primary literatureUnknownActiveShokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan2002
Hatano K, Nakao A
[Determination of sucralose in foods by HPLC using pre-column derivatization].Other primary literatureUnknownActiveShokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan2002
Nojiri S, Nakazato M, Kasuya Y, et al.
Dental considerations in sucralose use.Meta-analysisHuman & animalActiveThe Journal of clinical dentistry2002
Mandel ID, Grotz VL
Kinetics of enzymatic solid-to-solid peptide synthesis: synthesis of Z-aspartame and control of acid-base conditions by using inorganic salts.Other primary literatureUnknownActiveBiotechnology and bioengineering2001
Erbeldinger M, Ni X, Halling PJ
Aspartame: scientific evaluation in the postmarketing period.Other primary literatureHuman & animalActiveRegulatory toxicology and pharmacology : RTP2001
Butchko HH, Stargel WW
Aspartame prevents the karyomegaly induced by ochratoxin A in rat kidney.Other primary literatureAnimalActiveArchives of toxicology2001
Baudrimont I, Sostaric B, Yenot C, et al.
A comparison of chronic aspartame exposure to aspirin on inflammation, hyperalgesia and open field activity following carrageenan-induced monoarthritis.Other primary literatureAnimalActiveLife sciences2001
LaBuda CJ, Fuchs PN
Racemization of amino acids during classical and microwave oven hydrolysis--application to aspartame and a Maillard reaction systemOther primary literatureUnknownUnknownFood chemistry2001
Stenberg M, Marko-Varga G, Oste R
Selective continuous monitoring and analysis of mixtures of acesulfame-K, cyclamate, and saccharin in artificial sweetener tablets, diet soft drinks, yogurts, and wines using filter-supported bilayer lipid membranes.Other primary literatureUnknownActiveAnalytical chemistry2001
Nikolelis DP, Pantoulias S
Structure, dynamics, and stability of beta-cyclodextrin inclusion complexes of aspartame and neotame.Other primary literatureUnknownActiveJournal of agricultural and food chemistry2001
Garbow JR, Likos JJ, Schroeder SA
Investigation of solid-state reactions using variable temperature X-ray powder diffractrometry. I. Aspartame hemihydrate.Other primary literatureUnknownActivePharmaceutical research2001
Rastogi S, Zakrzewski M, Suryanarayanan R
Potentiation by nitric oxide synthase inhibitor and calcium channel blocker of aspartame-induced antinociception in the mouse formalin test.Other primary literatureAnimalActiveFundamental & clinical pharmacology2001
Abdollahi M, Nikfar S, Abdoli N
Migraine MLT-down: an unusual presentation of migraine in patients with aspartame-triggered headaches.Other primary literatureHumanActiveHeadache2001
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Aspartame effect in sickle cell anemia.Randomized controlled trialHumanActiveClinical pharmacology and therapeutics2001
Manion CV, Howard J, Ogle B, et al.
Aspartame degradation in solutions at various pH conditionsOther primary literatureUnknownUnknownJournal of food science2001
Pattanaargson S, Chuapradit C, Srisukphonraruk S
Interaction between potassium sorbate and aspartame in aqueous model sugar systemsOther primary literatureUnknownUnknownJournal of food science2001
Gliemmo MF, Campos CA, Gerschenson LN
Enhancement of sweetness ratings of aspartame by a vanilla odor presented either by orthonasal or retronasal routes.Other primary literatureHumanActivePerceptual and motor skills2001
Sakai N, Kobayakawa T, Gotow N, et al.
[Determination of sucralose in foods by anion-exchange chromatography and reverse-phase chromatography].Other primary literatureUnknownActiveShokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan2001
Kishi H, Kawana K
[Determination of sucralose in foods by HPLC].Other primary literatureUnknownActiveShokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan2001
Kobayashi C, Nakazato M, Yamajima Y, et al.
Partial substitution of sugars by the low-calorie sweetener sucralose in peach compoteOther primary literatureUnknownUnknownJournal of food science2001
Mendonca CR, Zambiazi R, Granada GG
What's the truth about the health risks of sugar substitutes such as saccharin and aspartame?Other primary literatureHuman & animalActiveHealth news (Waltham, Mass.)2001
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[NutraSweet--aspartame].Other primary literatureHumanActiveUgeskrift for laeger2001
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The effect of oral aspartame administration on the balance of magnesium in the rat.Other primary literatureAnimalActiveMagnesium research2001
Kovatsi L, Tsouggas M
Aspartame degradation study using electrospray ionization mass spectrometry.Other primary literatureUnknownActiveRapid communications in mass spectrometry : RCM2000
Pattanaargson S, Sanchavanakit C
Sweet taste of aspartame and sucrose: effects on diet-induced thermogenesis.Randomized controlled trialHumanActiveAppetite2000
Prat-Larquemin L, Oppert JM, Bellisle F, et al.
Acute effects of aspartame on aggression and neurochemistry of rats.Other primary literatureAnimalActiveLife sciences2000
Goerss AL, Wagner GC, Hill WL
Sucralose--an overview of the toxicity data.ReviewHuman & animalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2000
Grice HC, Goldsmith LA
Neurotoxicity studies on sucralose and its hydrolysis products with special reference to histopathologic and ultrastructural changes.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2000
Finn JP, Lord GH
Sucralose: lack of effects on sperm glycolysis and reproduction in the rat.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2000
Kille JW, Ford WC, McAnulty P, et al.
Sucralose metabolism and pharmacokinetics in man.Other primary literatureHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2000
Roberts A, Renwick AG, Sims J, et al.
Sucralose: assessment of teratogenic potential in the rat and the rabbit.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2000
Kille JW, Tesh JM, McAnulty PA, et al.
Acute and subchronic toxicity of sucralose.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2000
Goldsmith LA
A combined chronic toxicity/carcinogenicity study of sucralose in Sprague-Dawley rats.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2000
Mann SW, Yuschak MM, Amyes SJ, et al.
A carcinogenicity study of sucralose in the CD-1 mouse.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2000
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The pharmacokinetics and metabolism of sucralose in the dog.Other primary literatureHuman & animalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2000
Wood SG, John BA, Hawkins DR
The pharmacokinetics and metabolism of sucralose in the mouse.Other primary literatureHuman & animalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2000
John BA, Wood SG, Hawkins DR
The pharmacokinetics and metabolism of sucralose in the rabbit.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2000
John BA, Wood SG, Hawkins DR
The metabolic fate of sucralose in rats.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2000
Sims J, Roberts A, Daniel JW, et al.
Repeated dose study of sucralose tolerance in human subjects.Randomized controlled trialHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2000
Baird IM, Shephard NW, Merritt RJ, et al.
In vivo cytogenetic studies on blends of aspartame and acesulfame-K.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2000
Mukhopadhyay M, Mukherjee A, Chakrabarti J
Anxiety in mice following acute aspartame and ethanol exposure.Other primary literatureAnimalActiveAlcohol (Fayetteville, N.Y.)2000
LaBuda CJ, Hale RL
A minisensor for the rapid screening of sucralose based on surface-stabilized bilayer lipid membranes.Other primary literatureUnknownActiveBiosensors & bioelectronics2000
Nikolelis DP, Pantoulias S
Enzymatic catalysis of formation of Z-aspartame in ionic liquid - An alternative to enzymatic catalysis in organic solvents.Other primary literatureUnknownActiveBiotechnology progress2000
Erbeldinger M, Mesiano AJ, Russell AJ
Isothermal Fourier transform infrared microspectrosopic studies on the stability kinetics of solid-state intramolecular cyclization of aspartame sweetener.Other primary literatureHumanActiveJournal of agricultural and food chemistry2000
Cheng YD, Lin SY
Effects of beta-carotene and aspartame on clustogenic activity of cyclophosphamide and dioxidine in mice.Other primary literatureAnimalActiveBulletin of experimental biology and medicine2000
Belogolovskaya EG, Oreshchenko AV, Durnev AD, et al.
Aspartame loading test in PKU heterozygous individuals bearing severe and moderate mutations.Other primary literatureHumanActiveClinical genetics2000
da Silva LC, Carvalho TS, da Silva FB, et al.
Crystal structure of the low-humidity form of aspartame sweetener.Other primary literatureUnknownActiveThe journal of peptide research : official journal of the American Peptide Society2000
Meguro T, Kashiwagi T, Satow Y
Simultaneous formation and detection of the reaction product of solid-state aspartame sweetener by FT-IR/DSC microscopic system.Other primary literatureUnknownActiveFood additives and contaminants2000
Lin SY, Cheng YD
Effect of aspartame and fat on sweetness perception in yogurtOther primary literatureUnknownUnknownJournal of food science2000
King SC, Lawler PJ, Adams JK
Intermediate state during the crystal transition in aspartame, studied with thermal analysis, solid-state NMR, and molecular dynamics simulation.Other primary literatureUnknownActiveChemical & pharmaceutical bulletin2000
Ebisawa K, Nagashima N, Fukuhara K, et al.
On the sweetness of N-(trifluoroacetyl)aspartame.Other primary literatureHumanActiveBioscience, biotechnology, and biochemistry2000
Frank M, Aitken DJ
Induction of membrane chloride currents in Xenopus laevis oocytes by the sulfonyl amide sweeteners acesulfame K and saccharin.Other primary literatureAnimalActiveJournal of receptor and signal transduction research2000
Bufe B, Schmale H, Meyerhof W
Interference of rheumatoid factor activity by aspartame, a dipeptide methyl ester.Other primary literatureHumanActiveJournal of molecular recognition : JMR1999
Ramsland PA, Movafagh BF, Reichlin M, et al.
Interference of rheumatoid factor activity by aspartame, a dipeptide methyl ester.Other primary literatureHumanActiveJournal of molecular recognition : JMR1999
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Determination of aspartame by ion chromatography with electrochemical integrated amperometric detection.Other primary literatureUnknownActiveJournal of chromatography. A1999
Qu F, Qi ZH, Liu KN, et al.
Comments on the purported generation of formaldehyde and adduct formation from the sweetener aspartame.Other primary literatureAnimalActiveLife sciences1999
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Aspartame and the internet.Other primary literatureHumanActiveLancet (London, England)1999
Zehetner A, McLean M
Blood glucose and meal patterns in time-blinded males, after aspartame, carbohydrate, and fat consumption, in relation to sweetness perception.Randomized controlled trialHumanActiveThe British journal of nutrition1999
Melanson KJ, Westerterp-Plantenga MS, Campfield LA, et al.
Measurement of the relative sweetness of stevia extract, aspartame and cyclamate/saccharin blend as compared to sucrose at different concentrations.Other primary literatureHumanActivePlant foods for human nutrition (Dordrecht, Netherlands)1999
Cardello HM, Da Silva MA, Damasio MH
Urinary monitoring of saccharin and acesulfame-K as biomarkers of exposure to these additives.Other primary literatureHumanActiveFood additives and contaminants1999
Wilson LA, Wilkinson K, Crews HM, et al.
Intake of saccharin, aspartame, acesulfame K and cyclamate in Italian teenagers: present levels and projections.Other primary literatureHumanActiveFood additives and contaminants1999
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Aspartame and symptoms of carpal tunnel syndrome.Other primary literatureHumanActiveJournal of occupational and environmental medicine1999
Robbins PI, Raymond L
Comment on effect of large doses of aspartame on urinary calcium excretion.Other primary literatureHumanActiveThe Journal of clinical endocrinology and metabolism1999
Leon AS
[The antimutagenic activity of aspartame].Other primary literatureAnimalActiveEksperimental'naia i klinicheskaia farmakologiia1999
Kulakova AV, Belogolovskaia EG, Oreshchenko AV, et al.
Aspartame and breast and other cancers.Other primary literatureHumanCorrectedThe Western journal of medicine1999
Schwartz GR
Measurement of molecular interaction of aspartame and its metabolites with DNA.Other primary literatureUnknownActiveClinical biochemistry1998
Karikas GA, Schulpis KH, Reclos G, et al.
Treatment of osteoarthritis with aspartame.ReviewHuman & animalActiveClinical pharmacology and therapeutics1998
Edmundson AB, Manion CV
Formaldehyde derived from dietary aspartame binds to tissue components in vivo.Other primary literatureAnimalActiveLife sciences1998
Trocho C, Pardo R, Rafecas I, et al.
Aspartame consumption in rats selectively bred for high versus low saccharin intake.Other primary literatureAnimalActivePhysiology & behavior1998
De Francisco JC, Dess NK
Chemical stability of encapsulated aspartame in cakes without added sugarOther primary literatureUnknownUnknownFood chemistry1998
Wetzel CR, Bell LN
Molecular mechanisms of sweet taste 8*: saccharin, acesulfame-K, cyclamate and their derivativesOther primary literatureUnknownUnknownFood chemistry1998
Suami T, Hough L, Machinami T, et al.
Determination of aspartame and its degradation and epimerization products by capillary electrophoresis.Other primary literatureUnknownActiveJournal of pharmaceutical and biomedical analysis1998
Sabah S, Scriba GK
Solid-state characterization of two polymorphs of aspartame hemihydrate.Other primary literatureUnknownActiveJournal of pharmaceutical sciences1998
Leung SS, Padden BE, Munson EJ, et al.
Hydration and dehydration behavior of aspartame hemihydrate.Other primary literatureUnknownActiveJournal of pharmaceutical sciences1998
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Aspartame: neuropsychologic and neurophysiologic evaluation of acute and chronic effects.Randomized controlled trialHumanActiveThe American journal of clinical nutrition1998
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Sensory evaluation of mixtures of maltitol or aspartame, sucrose and an orange aroma.Other primary literatureHumanActiveChemical senses1998
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The effects of blind substitution of aspartame-sweetened for sugar-sweetened soft drinks on appetite and moodOther primary literatureUnknownUnknownBritish food journal (Croydon, England)1998
Reid M, Hammersley R
Standing up for aspartame.Other primary literatureHuman & animalActiveAWHONN lifelines1998
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Subchronic effects of ochratoxin A on young adult rat brain and partial prevention by aspartame, a sweetener.Other primary literatureAnimalActiveHuman & experimental toxicology1998
Belmadani A, Tramu G, Betbeder AM, et al.
Aspartame ingestion increases urinary calcium, but not oxalate excretion, in healthy subjects.Other primary literatureHumanActiveThe Journal of clinical endocrinology and metabolism1998
Nguyen UN, Dumoulin G, Henriet MT, et al.
How aspartame prevents the toxicity of ochratoxin A.Other primary literatureHuman & animalActiveThe Journal of toxicological sciences1998
Creppy EE, Baudrimont I, Anne-Marie
Regional tongue sensitivity for sweetness and pungency of ethanol-aspartame mixtures.Other primary literatureHumanActivePerceptual and motor skills1998
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[Simultaneous determination of aspartame and amino acids in fermented milk beverages by HPLC].Other primary literatureAnimalActiveSe pu = Chinese journal of chromatography1998
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Sucralose--a new artificial sweetener.Other primary literatureHuman & animalActiveThe Medical letter on drugs and therapeutics1998
Reduction of the ochratoxin A-induced cytotoxicity in Vero cells by aspartame.Other primary literatureAnimalActiveArchives of toxicology1997
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Aspartame and brain cancer.Other primary literatureHumanActiveLancet (London, England)1997
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In vivo cytogenetic studies on mice exposed to acesulfame-K--a non-nutritive sweetener.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association1997
Mukherjee A, Chakrabarti J
Photodecomposition of aspartame in aqueous solutionsOther primary literatureUnknownUnknownFood chemistry1997
Kim SK, Jung MY, Kim SY
Solid state stability studies of model dipeptides: aspartame and aspartylphenylalanine.Other primary literatureUnknownActiveJournal of pharmaceutical sciences1997
Leung SS, Grant DJ
The effect of sucrose- and aspartame-sweetened drinks on energy intake, hunger and food choice of female, moderately restrained eaters.Other primary literatureHumanActiveInternational journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity1997
Lavin JH, French SJ, Read NW
Amperometric bienzymic sensor for aspartame.Other primary literatureUnknownActiveThe Analyst1997
Compagnone D, O'Sullivan D, Guilbault GG
The effect of aspartame as part of a multidisciplinary weight-control program on short- and long-term control of body weight.Randomized controlled trialHumanActiveThe American journal of clinical nutrition1997
Blackburn GL, Kanders BS, Lavin PT, et al.
Aspartame consumption in relation to childhood brain tumor risk: results from a case-control study.Other primary literatureHumanCorrectedJournal of the National Cancer Institute1997
Gurney JG, Pogoda JM, Holly EA, et al.
Evaluation of an aspartame loading test for the detection of heterozygotes for classical phenylketonuria.Other primary literatureHumanActiveClinical genetics1997
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Cariostatic effect of aspartame in rats.Other primary literatureAnimalActiveCaries research1997
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[Rapid determination of aspartame in compound sweetening by reversed-phase high performance liquid chromatography].Other primary literatureUnknownActiveSe pu = Chinese journal of chromatography1997
Zhang R, Jiang M
"Increasing brain tumor rates: is there a link to aspartame?".Other primary literatureHuman & animalActiveJournal of neuropathology and experimental neurology1997
Flamm WG
"Increasing brain tumor rates: is there a link to aspartame?".Other primary literatureAnimalActiveJournal of neuropathology and experimental neurology1997
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Aspartame as a cause of allergic reactions, including anaphylaxis.Other primary literatureHumanActiveArchives of internal medicine1996
Roberts HJ
Simple and rapid high-performance liquid chromatographic method for the determination of aspartame and its metabolites in foods.Other primary literatureUnknownActiveJournal of chromatography. A1996
Gibbs BF, Alli I, Mulligan CN
Benzaldehyde formation from aspartame in the presence of ascorbic acid and transition metal catalyst.Other primary literatureUnknownUnknownJournal of agricultural and food chemistry1996
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Aspartame pharmacokinetics - the effect of ageing.Other primary literatureHumanActiveAge and ageing1996
Puthrasingam S, Heybroek WM, Johnston A, et al.
Aspartame pharmacokinetics: the effect of ageing.Other primary literatureHumanActiveAge and ageing1996
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An Equiratio Mixture Model for non-additive components: a case study for aspartame/acesulfame-K mixtures.Other primary literatureHumanActiveChemical senses1996
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Increasing brain tumor rates: is there a link to aspartame?Other primary literatureHuman & animalActiveJournal of neuropathology and experimental neurology1996
Olney JW, Farber NB, Spitznagel E, et al.
Optimizing acceptability of a high fruit-low sugar peach nectar using aspartame and guar gumOther primary literatureUnknownUnknownJournal of food science1996
Pastor MV, Costell E, Izquierdo L, et al.
Effect of sucralose in coffee on plaque pH in human subjects.Other primary literatureHumanActiveCaries research1996
Steinberg LM, Odusola F, Mandel ID
Effect of sucralose--alone or bulked with maltodextrin and/or dextrose--on plaque pH in humans.Other primary literatureHumanActiveCaries research1996
Meyerowitz C, Syrrakou EP, Raubertas RF
Glycemic effect of a single high oral dose of the novel sweetener sucralose in patients with diabetes.Randomized controlled trialHumanActiveDiabetes care1996
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The loss of aspartame during the storage of chewing gumOther primary literatureUnknownUnknownFlavor-food interactions1996
Schirle-Keller JP, Reineccius GA, Hatchwell LC
Aspartame as a preventive agent of chronic toxic effects of ochratoxin A in experimental animals.ReviewHuman & animalActiveFood additives and contaminants1996
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Synthesis of aspartame precursor with an immobilized thermolysin in mixed organic solvents.Other primary literatureUnknownActiveBiotechnology and bioengineering1995
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[The psychophysics of sweet taste. 7. New determination of sweet taste parameters of acesulfame, aspartame, cyclamate, saccharin, glucose and sorbitol].Other primary literatureHumanActiveDie Nahrung1995
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Sweet and bitter taste: structure and conformations of two aspartame dipeptide analogues.Other primary literatureHumanActiveJournal of peptide science : an official publication of the European Peptide Society1995
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Postingestive inhibition of food intake by aspartame: importance of interval between aspartame administration and subsequent eating.Other primary literatureHumanActivePhysiology & behavior1995
Rogers PJ, Burley VJ, Alikhanizadeh LA, et al.
Ethanol, nicotine, amphetamine, and aspartame consumption and preferences in C57BL/6 and DBA/2 mice.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior1995
Meliska CJ, Bartke A, McGlacken G, et al.
Glutamatergic receptor kinetics are not altered by perinatal exposure to aspartame.Other primary literatureAnimalActiveNeurochemistry international1995
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Aspartame-induced hives.Other primary literatureHumanActiveThe Journal of allergy and clinical immunology1995
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Aspartame degradation in solution as impacted by buffer type and concentration.Other primary literatureUnknownUnknownJournal of agricultural and food chemistry1995
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Erythrocyte L-aspartyl-L-phenylalanine hydrolase activity and plasma phenylalanine and aspartate concentrations in children consuming diets high in aspartame.Other primary literatureHumanActiveThe American journal of clinical nutrition1995
Stegink LD, Lindgren SD, Brummel MC, et al.
Prediction of sweetness intensity for equiratio aspartame/sucrose mixtures.Other primary literatureHumanActiveChemical senses1995
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Evolution of the sweetness receptor in primates. I. Why does alitame taste sweet in all prosimians and simians, and aspartame only in Old World simians?Other primary literatureHuman & animalActiveChemical senses1995
Glaser D, Tinti JM, Nofre C
Effects of aspartame on 45Ca influx and LDH leakage from nerve cells in culture.Other primary literatureAnimalActiveNeuroreport1995
Sonnewald U, Müller T, Unsgård G, et al.
Aspartame and seizure susceptibility: results of a clinical study in reportedly sensitive individuals.Randomized controlled trialHumanActiveEpilepsia1995
Rowan AJ, Shaywitz BA, Tuchman L, et al.
Aspartame does not affect aminergic and glutamatergic receptor kinetics in rat brain.Other primary literatureAnimalActiveAnnals of the New York Academy of Sciences1995
Reilly MA, Lajtha A
Aspartame and headache.Other primary literatureHumanActiveNeurology1995
Roberts HJ
Aspartame and headache.Other primary literatureHumanActiveNeurology1995
Levy PS, Hedeker D, Sanders PG
Aspartame and headache.Other primary literatureHumanActiveNeurology1995
Schiffman S
Effect of aqueous solutions of sucralose on plaque pH.Randomized controlled trialHumanActiveAmerican journal of dentistry1995
Steinberg LM, Odusola F, Yip J, et al.
[Use of HPLC technique for determination of aspartame and acesulfam-K in processed fruit products].Other primary literatureUnknownActiveRoczniki Panstwowego Zakladu Higieny1995
Szymczyk K, Czerwiecki L
Aspartame and memory loss.Other primary literatureHumanActiveJAMA1994
Moser RH
Aspartame has no effect on seizures or epileptiform discharges in epileptic children.Randomized controlled trialHumanActiveAnnals of neurology1994
Shaywitz BA, Anderson GM, Novotny EJ, et al.
Separation of alpha-hydroxy acid enantiomers by high performance capillary electrophoresis using copper(II)-L-amino acid and copper(II)-aspartame complexes as chiral selectors in the background electrolyte.Other primary literatureUnknownActiveElectrophoresis1994
Desiderio C, Aturki Z, Fanali S
Solvent effects on chemical processes. 8. Demethylation kinetics of aspartame in binary aqueous-organic solvents.Other primary literatureUnknownActiveJournal of pharmaceutical sciences1994
Skwierczynski RD, Connors KA
Microbial cometabolism of sucralose, a chlorinated disaccharide, in environmental samples.Other primary literatureUnknownCorrectedApplied microbiology and biotechnology1994
Labare MP, Alexander M
Neuropsychological and biochemical investigations in heterozygotes for phenylketonuria during ingestion of high dose aspartame (a sweetener containing phenylalanine).Randomized controlled trialHumanActiveHuman genetics1994
Trefz F, de Sonneville L, Matthis P, et al.
"Adverse reactions to aspartame: double-blind challenge in patients from a vulnerable population" by Walton et al.Randomized controlled trialHumanActiveBiological psychiatry1994
Butchko HH
Effect of high-protein meal plus aspartame ingestion on plasma phenylalanine concentrations in obligate heterozygotes for phenylketonuria.Other primary literatureHumanActiveMetabolism: clinical and experimental1994
Curtius HC, Endres W, Blau N
Reanalysis of the effects of phenylalanine, alanine, and aspartame on food intake in human subjects.Randomized controlled trialHumanActivePhysiology & behavior1994
Rogers PJ, Blundell JE
Enzymatic method for the spectrophotometric determination of aspartameOther primary literatureUnknownUnknownFood chemistry1994
Dinckaya E, Cagin M, Telefoncu A
Stability of N-derivatized and alpha-methyl analogues of aspartame to hydrolysis by mammalian cell-surface peptidases.Other primary literatureUnknownUnknownJournal of agricultural and food chemistry1994
Hooper NM, Hesp RJ, Tieku S, et al.
Differentiating between the effects of water activity and glass transition dependent mobility on a solid state chemical reaction: aspartame degradation.Other primary literatureUnknownUnknownJournal of agricultural and food chemistry1994
Bell LN, Hageman MJ
Flow injection spectrophotometric determination of aspartame in dietary products.Other primary literatureUnknownActiveThe Analyst1994
Nóbrega Jde A, Fatibello-Filho O, Vieira Ida C
Metabolism of aspartame by human and pig intestinal microvillar peptidases.Other primary literatureHuman & animalActiveThe Biochemical journal1994
Hooper NM, Hesp RJ, Tieku S
Effects of diets high in sucrose or aspartame on the behavior and cognitive performance of children.Randomized controlled trialHumanActiveThe New England journal of medicine1994
Wolraich ML, Lindgren SD, Stumbo PJ, et al.
Molecular mechanisms of sweet taste. V. Sucralose and its derivativesOther primary literatureUnknownUnknownJournal of carbohydrate chemistry1994
Suami T, Hough L, Tsuboi M, et al.
Comparing the effects of aspartame and sucrose on motivational ratings, taste preferences, and energy intakes in humans.Other primary literatureHumanActiveThe American journal of clinical nutrition1994
Drewnowski A, Massien C, Louis-Sylvestre J, et al.
The effect of age on the recognition thresholds of three sweeteners: sucrose, saccharin and aspartame.Other primary literatureHumanActiveGerodontology1994
Easterby-Smith V, Besford J, Heath MR
Does sucrose or aspartame cause hyperactivity in children?ReviewHumanActiveNutrition reviews1994
Kanarek RB
The development and applications of sucralose, a new high-intensity sweetener.ReviewHuman & animalActiveCanadian journal of physiology and pharmacology1994
Knight I
Aspartame ingestion and headaches: a randomized crossover trial.Randomized controlled trialHumanActiveNeurology1994
Van den Eeden SK, Koepsell TD, Longstreth WT Jr, et al.
Aspartame, behavior, and cognitive function in children with attention deficit disorder.Randomized controlled trialHumanActivePediatrics1994
Shaywitz BA, Sullivan CM, Anderson GM, et al.
Aspartame stability in commercially sterilized flavored dairy beverages.Other primary literatureAnimalActiveJournal of dairy science1994
Bell LN, Labuza TP
Aspartame and attention deficit disorder (ADD)Other primary literatureHumanActivePediatrics1994
Krohn JA
The effects of aspartame versus sucrose on motivational ratings, taste preferences, and energy intakes in obese and lean women.Other primary literatureHumanActiveInternational journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity1994
Drewnowski A, Massien C, Louis-Sylvestre J, et al.
Effects of alcohol and chronic aspartame ingestion upon performance in aviation relevant cognitive tasks.Randomized controlled trialHumanActiveAviation, space, and environmental medicine1994
Stokes AF, Belger A, Banich MT, et al.
Stabilization of aspartame by polyethylene glycol 400.Other primary literatureUnknownActiveJournal of pharmaceutical sciences1993
Yalkowsky SH, Davis E, Clark T
Aspartame and seizures.Other primary literatureUnknownActiveAmino acids1993
Jobe PC, Dailey JW
An improved FIA biosensor for the determination of aspartame in dietary food products.Other primary literatureUnknownActiveApplied biochemistry and biotechnology1993
Male KB, Luong JH, Gibbs B, et al.
Adverse reactions to aspartame: double-blind challenge in patients from a vulnerable population.Other primary literatureHumanActiveBiological psychiatry1993
Walton RG, Hudak R, Green-Waite RJ
Consuming aspartame with and without taste: differential effects on appetite and food intake of young adult males.Randomized controlled trialHumanActivePhysiology & behavior1993
Black RM, Leiter LA, Anderson GH
Aspartame is no more likely than placebo to cause urticaria/angioedema: results of a multicenter, randomized, double-blind, placebo-controlled, crossover study.Randomized controlled trialHumanActiveThe Journal of allergy and clinical immunology1993
Geha R, Buckley CE, Greenberger P, et al.
Mutagenic activity of peptides and the artificial sweetener aspartame after nitrosation.ReviewHuman & animalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association1993
Shephard SE, Wakabayashi K, Nagao M
Molecular mechanisms of sweet taste. 3. Aspartame and its non-sweet isomersOther primary literatureUnknownUnknownFood chemistry1993
Suami T, Hough L
Demethylation kinetics of aspartame and L-phenylalanine methyl ester in aqueous solution.Other primary literatureUnknownActivePharmaceutical research1993
Skwierczynski RD, Connors KA
Determination of aspartame and its major decomposition products in foods.Other primary literatureAnimalActiveJournal of AOAC International1993
Prodolliet J, Bruelhart M
Fat concentration affects sweetness and sensory profiles of sucrose, sucralose, and aspartameOther primary literatureUnknownUnknownJournal of food science1993
Wiet SG, Ketelsen SM, Davis TR, et al.
Aspartame as a source of essential phenylalanine for the growth of oral anaerobes.Other primary literatureHumanActiveFEMS microbiology letters1993
Wyss C
Aspartame and seizures.Other primary literatureHumanActiveNeurology1993
Eshel Y, Sarova-Pinhas I
Aspartame use in Parkinson's disease.Other primary literatureHumanActiveNeurology1993
Karstaedt PJ, Pincus JH
Aspartame and seizures.Other primary literatureHumanActiveNeurology1993
Shaywitz BA, Novotny EJ Jr
Biochemical and clinical effects of aspartame in patients with chronic, stable alcoholic liver disease.Randomized controlled trialHuman & animalActiveThe American journal of gastroenterology1993
Hertelendy ZI, Mendenhall CL, Rouster SD, et al.
Biocatalytic synthesis of disaccharide high-intensity sweeterner sucralose via a tetrachlororaffinose intermediate.Other primary literatureUnknownActiveBiotechnology and bioengineering1992
Bennett C, Dordick JS, Hacking AJ, et al.
Absence of an effect of aspartame on seizures induced by electroshock in epileptic and non-epileptic rats.Other primary literatureUnknownActiveAmino acids1992
Jobe PC, Lasley SM, Burger RL, et al.
Analysis of acesulfame-K, saccharin and preservatives in beverages and jams by HPLC.Other primary literatureUnknownActiveZeitschrift fur Lebensmittel-Untersuchung und -Forschung1992
Hannisdal A
Baking stability of acesulfame K.Other primary literatureUnknownActiveZeitschrift fur Lebensmittel-Untersuchung und -Forschung1992
Klug C, von Rymon Lipinski GW, Böttger D
An analysis of FDA passive surveillance reports of seizures associated with consumption of aspartame.Other primary literatureHumanActiveJournal of the American Dietetic Association1992
Tollefson L, Barnard RJ
Aspartame-induced lobular panniculitis.Other primary literatureHumanActiveJournal of the American Academy of Dermatology1992
Geha RS
Influence of dairy proteins on aspartame stability in the pH 6-7 rangeOther primary literatureUnknownUnknownJournal of food science1992
Tsoubeli MN, Labuza TP
Sensory characteristics of sucralose and other high intensity sweetenersOther primary literatureUnknownUnknownJournal of food science1992
Wiet SG, Beyts PK
Plasma concentrations and pharmacokinetics of phenylalanine in rats and mice administered aspartame.Other primary literatureHuman & animalActivePharmacology1992
Hjelle JJ, Dudley RE, Marietta MP, et al.
Effect of dietary aspartame on plasma concentrations of phenylalanine and tyrosine in normal and homozygous phenylketonuric patients.Other primary literatureHumanActiveClinical pediatrics1992
Mackey SA, Berlin CM Jr
The effects of sucralose, xylitol, and sorbitol on remineralization of caries lesions in rats.Other primary literatureAnimalActiveJournal of dental research1992
Bowen WH, Pearson SK
Aspartame exacerbates EEG spike-wave discharge in children with generalized absence epilepsy: a double-blind controlled study.Other primary literatureHumanActiveNeurology1992
Camfield PR, Camfield CS, Dooley JM, et al.
Aspartame and dizziness: preliminary results of a prospective, nonblinded, prevalence and attempted cross-over study.Other primary literatureHumanActiveThe American journal of otology1992
Gulya AJ, Sessions RB, Troost TR
Stability of aspartame in water: organic solvent mixtures with different dielectric constants.Other primary literatureUnknownActiveJournal of pharmaceutical sciences1991
Sanyude S, Locock RA, Pagliaro LA
Aspartame degradation as a function of "water activity".ReviewUnknownActiveAdvances in experimental medicine and biology1991
Bell LN, Labuza TP
Intestinal absorption of aspartame decomposition products in adult rats.Other primary literatureAnimalActiveMetabolism: clinical and experimental1991
Lipton WE, Li YN, Younoszai MK, et al.
Metabolism of aspartame and its L-phenylalanine methyl ester decomposition product by the porcine gut.Other primary literatureAnimalActiveMetabolism: clinical and experimental1991
Burgert SL, Andersen DW, Stegink LD, et al.
Further analysis of the short-term inhibition of food intake in humans by the dipeptide L-aspartyl-L-phenylalanine methyl ester (aspartame).Other primary literatureHumanActivePhysiology & behavior1991
Rogers PJ, Keedwell P, Blundell JE
Soft drinks with aspartame: effect on subjective hunger, food selection, and food intake of young adult males.Other primary literatureHumanActivePhysiology & behavior1991
Black RM, Tanaka P, Leiter LA, et al.
Immunoreactive beta-endorphin increases after an aspartame chocolate drink in healthy human subjects.Randomized controlled trialHumanActivePhysiology & behavior1991
Melchior JC, Rigaud D, Colas-Linhart N, et al.
A combined single-blind, double-blind, placebo-controlled study to determine the reproducibility of hypersensitivity reactions to aspartame.Randomized controlled trialHumanActiveThe Journal of allergy and clinical immunology1991
Garriga MM, Berkebile C, Metcalfe DD
No change in spontaneous behavior of rats after acute oral doses of aspartame, phenylalanine, and tyrosine.Other primary literatureAnimalActiveFundamental and applied toxicology : official journal of the Society of Toxicology1991
Mullenix PJ, Tassinari MS, Schunior A, et al.
Effect of tyrosine on the potentiation by aspartame and phenylalanine of metrazol-induced convulsions in rats.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association1991
Guiso G, Diomede L, Romano M, et al.
Interspecies and interstrain studies on the increased susceptibility to metrazol-induced convulsions in animals given aspartame.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association1991
Diomede L, Romano M, Guiso G, et al.
High doses of aspartame have no effects on sensorimotor function or learning and memory in rats.Other primary literatureAnimalActiveNeurotoxicology and teratology1991
Tilson HA, Hong JS, Sobotka TJ
Amino acids, monoamines and audiogenic seizures in genetically epilepsy-prone rats: effects of aspartame.Other primary literatureAnimalActiveEpilepsy research1991
Dailey JW, Lasley SM, Burger RL, et al.
Aspartame-induced lobular panniculitis.Other primary literatureHumanActiveJournal of the American Academy of Dermatology1991
McCauliffe DP, Poitras K
N-formylcarbamoylaspartame, a new aspartame-like sweetener. Synthesis and studies on stability and biological properties.Other primary literatureUnknownUnknownJournal of agricultural and food chemistry1991
Boesten WHJ, Dassen BHN, Kleinjans JCS, et al.
Acceptable daily intake vs actual intake: the aspartame example.ReviewHuman & animalActiveJournal of the American College of Nutrition1991
Butchko HH, Kotsonis FN
In vivo tyrosine hydroxylation in rat retina: effect of aspartame ingestion in rats pretreated with p-chlorophenylalanine.Other primary literatureAnimalActiveThe American journal of clinical nutrition1991
Fernstrom JD, Fernstrom MH, Massoudi MS
Aspartame.Other primary literatureHumanActiveSouthern medical journal1991
Moser RH
Stability of aspartame in fruit preparations used in yogurtOther primary literatureUnknownUnknownJournal of food science1991
Fellows JW, Chang SW, Shazer WH
Comparison of temporal perception of fruitiness in model systems sweetened with aspartame, an aspartame + acesulfame K blend, or sucroseOther primary literatureUnknownUnknownJournal of food science1991
Matysiak NL, Noble AC
Destructive effect of aspartame on ascorbic acid in Cu-catalyzed solutionsOther primary literatureUnknownUnknownJournal of food science1991
Hsieh YP, Harris ND
Aspartame degradation kinetics as affected by pH in intermediate and low moisture food systemsOther primary literatureUnknownUnknownJournal of food science1991
Bell LN, Labuza TP
Degradation of aspartame in yogurt related to microbial growthOther primary literatureUnknownUnknownJournal of food science1991
Keller SE, Newberg SS, Krieger TM, et al.
Modification of fruit flavors by aspartame and sucroseOther primary literatureUnknownUnknownJournal of food science1991
Wiseman JJ, McDaniel MR
Accelerated kinetic study of aspartame degradation in the neutral pH rangeOther primary literatureUnknownUnknownJournal of food science1991
Tsoubeli MN, Labuza TP
Conformation and hydration of aspartame.Other primary literatureUnknownActiveInternational journal of peptide and protein research1991
Kang YK
Effect of aspartame-derived phenylalanine on neutral amino acid uptake in human brain: a positron emission tomography study.Other primary literatureHumanActiveJournal of neurochemistry1991
Koeppe RA, Shulkin BL, Rosenspire KC, et al.
Aspartame, headaches and beta blockers.Other primary literatureHumanActiveHeadache1991
Watts RS
Effect of aspartame and protein, administered in phenylalanine-equivalent doses, on plasma neutral amino acids, aspartate, insulin and glucose in man.Other primary literatureHumanActivePharmacology & toxicology1991
Møller SE
Aspartame and sucrose produce a similar increase in the plasma phenylalanine to large neutral amino acid ratio in healthy subjects.Randomized controlled trialHumanActivePharmacology1991
Burns TS, Stargel WW, Tschanz C, et al.
Sucralose: how to make sugar sweeterOther primary literatureUnknownUnknownACS Symposium series - American Chemical Society1991
Jenner MR
Molecular mechanics of cyclopropane peptide analogs of aspartame: implications for three-dimensional requirements of the sweet taste receptorOther primary literatureUnknownUnknownACS Symposium series - American Chemical Society1991
Taylor EW, Wilson S, Stammer CH
Aspartame and dental caries in the rat.Other primary literatureAnimalActivePediatric dentistry1991
Das S, Das AK, Murphy RA, et al.
Effects of acute aspartame and acute alcohol ingestion upon the cognitive performance of pilots.Randomized controlled trialHumanActiveAviation, space, and environmental medicine1991
Stokes AF, Belger A, Banich MT, et al.
The stereochemical resolution of the enantiomers of aspartame on an immobilized alpha-chymotrypsin HPLC chiral stationary phase: the effect of mobile-phase composition and enzyme activity.Other primary literatureUnknownActiveChirality1990
Jadaud P, Wainer IW
The neuropsychiatric effects of aspartame in normal volunteers.Randomized controlled trialHumanActiveJournal of clinical pharmacology1990
Lapierre KA, Greenblatt DJ, Goddard JE, et al.
Long-term continuous synthesis of aspartame precursor in a column reactor with an immobilized thermolysin.Other primary literatureUnknownActiveApplied microbiology and biotechnology1990
Nakanishi K, Takeuchi A, Matsuno R
Effect of aspartame on N-methyl-D-aspartate-sensitive L-[3H]glutamate binding sites in rat brain synaptic membranes.Other primary literatureAnimalActiveBrain research1990
Pan-Hou H, Suda Y, Ohe Y, et al.
Bioavailability of phenylalanine and aspartate from aspartame (20 mg/kg) in capsules and solution.Randomized controlled trialHumanActiveMetabolism: clinical and experimental1990
Burns TS, Stargel WW, Hurwitz A
Repeated ingestion of aspartame-sweetened beverages: further observations in individuals heterozygous for phenylketonuria.Randomized controlled trialHumanActiveMetabolism: clinical and experimental1990
Stegink LD, Filer LJ Jr, Bell EF, et al.
Aspartame ingestion with and without carbohydrate in phenylketonuric and normal subjects: effect on plasma concentrations of amino acids, glucose, and insulin.Other primary literatureHumanActiveMetabolism: clinical and experimental1990
Wolf-Novak LC, Stegink LD, Brummel MC, et al.
Oral stimulation with aspartame increases hunger.Other primary literatureHumanActivePhysiology & behavior1990
Tordoff MG, Alleva AM
Effects of drinks sweetened with sucrose or aspartame on hunger, thirst and food intake in men.Other primary literatureHumanActivePhysiology & behavior1990
Rolls BJ, Kim S, Fedoroff IC
Effects of aspartame and sucrose on hunger and energy intake in humans.Other primary literatureHumanActivePhysiology & behavior1990
Mattes R
Aspartame ingested without tasting inhibits hunger and food intake.Other primary literatureHumanActivePhysiology & behavior1990
Rogers PJ, Pleming HC, Blundell JE
Nitrosation of aspartic acid, aspartame, and glycine ethylester. Alkylation of 4-(p-nitrobenzyl)pyridine (NBP) in vitro and binding to DNA in the rat.Other primary literatureAnimalActiveMutation research1990
Meier I, Shephard SE, Lutz WK
Plasma and brain kinetics of large neutral amino acids and of striatum monoamines in rats given aspartame.Other primary literatureAnimalActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association1990
Romano M, Diomede L, Guiso G, et al.
Aspartame- or sugar-sweetened beverages: effects on mood in young women.Other primary literatureHumanActiveJournal of the American Dietetic Association1990
Pivonka EE, Grunewald KK
Direct stereochemical resolution of aspartame stereoisomers and their degradation products by high-performance liquid chromatography on a chiral crown ether based stationary phase.Other primary literatureUnknownActiveJournal of chromatography1990
Motellier S, Wainer IW
The effect of aspartame on the activity of rat liver xenobiotic-metabolizing enzymes.Other primary literatureAnimalActiveDrug metabolism and disposition: the biological fate of chemicals1990
Tutelyan VA, Kravchenko LV, Kuzmina EE
Conformation-activity relationship of sweet molecules. Comparison of aspartame and naphthimidazolesulfonic acids.Other primary literatureUnknownActiveJournal of medicinal chemistry1990
Castiglione-Morelli MA, Lelj F, Naider F, et al.
Enzymic method for the spectrophotometric determination of aspartame in beverages.Other primary literatureUnknownActiveThe Analyst1990
Hamano T, Mitsuhashi Y, Aoki N, et al.
Dynamic response characteristics of the potentiometric carbon dioxide sensor for the determination of aspartame.Other primary literatureUnknownActiveThe Analyst1990
Nikolelis DP, Krull UJ
Similarity assessment and attribute scaling of sucrose and aspartame in grape drink.Randomized controlled trialHumanActiveJournal of the American College of Nutrition1990
Christensen L, Archer S
Comparative effects of fructose, aspartame, glucose, and water preloads on calorie and macronutrient intake.Randomized controlled trialHumanActiveThe American journal of clinical nutrition1990
Rodin J
Effect of drinking soda sweetened with aspartame or high-fructose corn syrup on food intake and body weight.Other primary literatureHumanActiveThe American journal of clinical nutrition1990
Tordoff MG, Alleva AM
Effect of sucrose on the metabolic disposition of aspartame.Other primary literatureHumanActiveThe American journal of clinical nutrition1990
Stegink LD, Brummel MC, Persoon TJ, et al.
Aspartame, tryptophan, and other amino acids as potentially hazardous experiments.Other primary literatureHumanActiveSouthern medical journal1990
Roberts HJ
The influence of sucralose on bacterial metabolism.Other primary literatureHumanActiveJournal of dental research1990
Young DA, Bowen WH
The effects of sucralose on coronal and root-surface caries.Other primary literatureAnimalActiveJournal of dental research1990
Bowen WH, Young DA, Pearson SK
Aspartame: effects on learning, behavior, and mood.Other primary literatureHumanActivePediatrics1990
Saravis S, Schachar R, Zlotkin S, et al.
Acute effects of aspartame on concentrations of brain amines and their metabolites in selected brain regions of Fischer 344 and Sprague-Dawley rats.Other primary literatureAnimalActiveDrug and chemical toxicology1990
Freeman G, Sobotka T, Hattan D
Safe ingestion of aspartame during pregnancyOther primary literatureUnknownUnknownTopics in clinical nutrition1990
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Safe ingestion of aspartame during pregnancy.Other primary literatureUnknownUnknownTopics in clinical nutrition1990
Carroll P
Aspartame: clinical update.Other primary literatureHumanActiveConnecticut medicine1990
Butchko HH
Aspartame: ensuring safe intake levels in children.Other primary literatureHumanActiveJournal of the American Dietetic Association1990
Safety of long-term large doses of aspartame.Randomized controlled trialHumanActiveArchives of internal medicine1989
Leon AS, Hunninghake DB, Bell C, et al.
Oral aspartame and plasma phenylalanine: pharmacokinetic difference between rodents and man, and relevance to CNS effects of phenylalanine. Short note.Other primary literatureHuman & animalActiveJournal of neural transmission1989
Fernstrom JD
Lack of effect of chronic aspartame ingestion on aminergic receptors in rat brain.Other primary literatureAnimalActiveBiochemical pharmacology1989
Reilly MA, Debler EA, Fleischer A, et al.
Effect of repeated ingestion of aspartame-sweetened beverage on plasma amino acid, blood methanol, and blood formate concentrations in normal adults.Other primary literatureHumanActiveMetabolism: clinical and experimental1989
Stegink LD, Filer LJ Jr, Bell EF, et al.
Repeated ingestion of aspartame-sweetened beverage: effect on plasma amino acid concentrations in individuals heterozygous for phenylketonuria.Randomized controlled trialHumanActiveMetabolism: clinical and experimental1989
Stegink LD, Filer LJ Jr, Baker GL, et al.
Failure of aspartame to affect seizure susceptibility in kindled rats.Other primary literatureAnimalActiveNeuropharmacology1989
Cain DP, Boon F, Bevan M
Children's food intake following drinks sweetened with sucrose or aspartame: time course effects.Other primary literatureHumanActivePhysiology & behavior1989
Birch LL, McPhee L, Sullivan S
Aspartame fails to facilitate pentylenetetrazol-induced convulsions in CD-1 mice.Other primary literatureAnimalActiveToxicology and applied pharmacology1989
Dailey JW, Lasley SM, Mishra PK, et al.
Behavioral assessment of the toxicity of aspartame.Other primary literatureAnimalActivePharmacology, biochemistry, and behavior1989
Holder MD, Yirmiya R
Aspartame: effect on lunch-time food intake, appetite and hedonic response in children.Other primary literatureHumanActiveAppetite1989
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Absence of developmental effects in CF-1 mice exposed to aspartame in utero.Other primary literatureAnimalActiveFundamental and applied toxicology : official journal of the Society of Toxicology1989
McAnulty PA, Collier MJ, Enticott J, et al.
Impaired performance on odor-aversion testing following prenatal aspartame exposure in the guinea pig.Other primary literatureHuman & animalActiveNeurotoxicology and teratology1989
Dow-Edwards DL, Scribani LA, Riley EP
Effects of perinatal exposure to aspartame on rat pups.Other primary literatureAnimalActiveNeurotoxicology and teratology1989
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Lack of effect of aspartame or of L-phenylalanine on photically induced myoclonus in the baboon, Papio papio.Other primary literatureAnimalActiveEpilepsy research1989
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The genetics of tasting in mice. VI. Saccharin, acesulfame, dulcin and sucrose.Other primary literatureAnimalActiveGenetical research1989
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Aspartame and its constituent amino acids: effects on prolactin, cortisol, growth hormone, insulin, and glucose in normal humans.Other primary literatureHumanActiveThe American journal of clinical nutrition1989
Carlson HE, Shah JH
Effect of aspartame on plasma amino acid profiles of diabetic patients with chronic renal failure.Randomized controlled trialHumanActiveThe American journal of clinical nutrition1989
Gupta V, Cochran C, Parker TF, et al.
Metabolic effects of adding sucrose and aspartame to the diet of subjects with noninsulin-dependent diabetes mellitus.Other primary literatureHumanActiveThe American journal of clinical nutrition1989
Colagiuri S, Miller JJ, Edwards RA
Determination of aspartame in beverages using an alcohol oxidase enzyme electrode.Other primary literatureUnknownActiveJournal - Association of Official Analytical Chemists1989
Smith VJ, Green RA, Hopkins TR
Effects of aspartame and carbohydrate administration on human and rat plasma large neutral amino acid levels and rat brain amino acid and monoamine levels.Other primary literatureHuman & animalActiveThe Journal of nutrition1989
Romano M, Casacci F, De Marchi F, et al.
Physicochemical properties of the sweetener sucraloseOther primary literatureUnknownUnknownJournal of food science1989
Jenner MR, Smithson A
An ion-pair high performance liquid chromatographic method for the determination of aspartame and its decomposition productsOther primary literatureUnknownUnknownJournal of food science1989
Stamp JA, Labuza TP
Aspartame as a dietary trigger of headache.Other primary literatureHumanActiveHeadache1989
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Aspartame metabolism in normal adults, phenylketonuric heterozygotes, and diabetic subjects.Other primary literatureHumanActiveDiabetes care1989
Filer LJ Jr, Stegink LD
Oral administration of aspartame is not proconvulsant in rats.Other primary literatureAnimalActiveNeurotoxicology1989
Tilson HA, Thai L, Zhao D, et al.
Aspartame and phenylalanine do not enhance theophylline-induced seizures in rats.Other primary literatureAnimalActiveResearch communications in chemical pathology and pharmacology1989
Zhi JQ, Levy G
Clinical safety of aspartame.ReviewHumanActiveAmerican family physician1989
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Aspartame: clinical update.ReviewHumanActiveConnecticut medicine1989
Potenza DP, el-Mallakh RS
[New data on the metabolism and physiologic mechanisms of aspartame action].Other primary literatureHuman & animalActiveVoprosy pitaniia1989
Tutel'ian VA, Gapparov MM, Virovets OA, et al.
Calculation of aspartame intake in children.Other primary literatureHumanActiveJournal of the American Dietetic Association1989
Thomas-Dobersen D
Repeated ingestion of aspartame-sweetened beverage: effect on plasma amino acid concentrations in normal adults.Randomized controlled trialHumanActiveMetabolism: clinical and experimental1988
Stegink LD, Filer LJ Jr, Baker GL
Administration of aspartame potentiates pentylenetetrazole- and fluorothyl-induced seizures in mice.Other primary literatureAnimalActiveNeuropharmacology1988
Pinto JM, Maher TJ
Effect of aspartame on seizures in various models of experimental epilepsy.Other primary literatureAnimalActiveToxicology and applied pharmacology1988
Guiso G, Caccia S, Vezzani A, et al.
Aspartame exposure and in vitro hippocampal slice excitability and plasticity.Other primary literatureAnimalActiveFundamental and applied toxicology : official journal of the Society of Toxicology1988
Fountain SB, Hennes SK, Teyler TJ
Aspartame--a bit of a headache?Other primary literatureHumanActiveFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association1988
Copestake P
Aspartame: review of recent experimental and observational data.ReviewHuman & animalActiveToxicology1988
Janssen PJ, van der Heijden CA
Aspartame and the rat brain monoaminergic system.Other primary literatureAnimalActiveToxicology letters1988
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Carbohydrate ingestion and brain serotonin synthesis: relevance to a putative control loop for regulating carbohydrate ingestion, and effects of aspartame consumption.ReviewAnimalActiveAppetite1988
Fernstrom JD
Effects of aspartame and phenylalanine on meal-time food intake of humans.ReviewHumanActiveAppetite1988
Anderson GH, Leiter LA
Comparison of the effects of aspartame and sucrose on appetite and food intake.Other primary literatureHumanActiveAppetite1988
Rolls BJ, Hetherington M, Laster LJ
Use of aspartame to test the "body weight set point" hypothesis.Other primary literatureHumanActiveAppetite1988
Van Itallie TB, Yang MU, Porikos KP
An evaluation of the effect of aspartame on weight loss.Randomized controlled trialHumanActiveAppetite1988
Kanders BS, Lavin PT, Kowalchuk MB, et al.
Bienzymatic electrode for the determination of aspartame in dietary products.Other primary literatureUnknownCorrectedAnalytical chemistry1988
Fatibello-Filho O, Suleiman AA, Guilbault GG, et al.
Spectrophotometric determination of aspartame in soft drinks with ninhydrin as reagent.Other primary literatureUnknownActiveThe Analyst1988
Lau OW, Luk SF, Chan WM
Aspartame and headache.Other primary literatureHumanActiveThe New England journal of medicine1988
The effect of aspartame on migraine headache.Other primary literatureHumanActiveHeadache1988
Koehler SM, Glaros A
Synthesis, taste properties, and conformational analysis of four stereoisomeric cyclopropane analogs of aspartame.Other primary literatureHumanActiveInternational journal of peptide and protein research1988
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Aspartame and headache.Other primary literatureHumanActiveHeadache1988
Edmeads J
Aspartame and headache.Other primary literatureHumanActiveHeadache1988
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Apparent synergism between the interaction of saccharin, acesulfame K, and fluoride with hexitol metabolism by Streptococcus mutans.Other primary literatureUnknownActiveCaries research1988
Brown AT, Best GM
Cariogenicity of frequent aspartame and sorbitol rinsing in laboratory rats.Other primary literatureAnimalActiveCaries research1988
Lout RK, Messer LB, Soberay A, et al.
Response to single dose of aspartame or saccharin by NIDDM patients.Randomized controlled trialHumanActiveDiabetes care1988
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More evidence on the safety of aspartameOther primary literatureUnknownUnknownTufts University diet & nutrition letter1988
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New aspartame-sweetened products to appear on supermarket shelves.Other primary literatureUnknownUnknownEnvironmental nutrition1988
Aspartame intolerance.ReviewHumanActiveAnnals of allergy1988
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A metabolite of aspartame inhibits angiotensin converting enzyme.Other primary literatureUnknownActiveBiochemical and biophysical research communications1985
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The effects of Acesulfame Potassium injection in the prenatal period on adult spermatogenesisDesign not determinedUnknownUnknown
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Sucralose or rebaudioside A at recommended doses did not alter the gut microbiota composition in rats under two dietary conditionsDesign not determinedUnknownUnknown
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Dietary sucrose, sucralose and probiotic sweetener isomaltooligosaccharide divergently affect exercise induced weight loss and its associated skeletal muscle metabolismDesign not determinedUnknownUnknown
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Low-doses of Sucralose Alters Fecal Microbiota in High-fat Diet Induced Obese RatsDesign not determinedUnknownUnknown
Zhang M, Chen J, Yang M, et al.
Synthesis and characterization of PSF-g-Sucralose-g-PANI/Fe2O3 nanocomposite membrane: Water filtration and nano dispersion studyDesign not determinedUnknownUnknown
Anbarasan R, Thamizhlarasan A, Meenarathi B, et al.
Aspartame Drives the Continuous Progression from MASLD to HCC: An Integrated AnalysisDesign not determinedUnknownUnknown
Zhang X, Tan R, Ma Y, et al.
NMR Based Real-Time Enzyme Kinetics on Estimating the Inhibitory Effect of Sucralose in the Enzymatic Conversion of SucroseDesign not determinedUnknownUnknown
Vang J, Her C, Krishnan K
METHOD OF IMPROVING THE PROFILE OF THE RELEASE OF THE SWEETNESS DELIVERY OF SUCRALOSEDesign not determinedUnknownUnknown
MERKEL CAROLYN, LINDLEY MICHAEL
COMPOSITIONS CONTAINING SUCRALOSEDesign not determinedUnknownUnknown
SZYMCZAK CHRISTOPHER E
EDIBLE FILMS INCLUDING ASPARTAME AND METHODS OF MAKING SAMEDesign not determinedUnknownUnknown
LEVAKOV VUKASIN, BARABOLAK ROMAN M, GREY RONALD T, et al.
IMPROVED CRYSTALLINE FORM OF SUCRALOSE, AND METHOD FOR PRODUCING ITDesign not determinedUnknownUnknown
VERNON NICHOLAS M, MERKEL CAROLYN M, CATANI STEVEN J
GRANULATED SUCRALOSE PRODUCTDesign not determinedUnknownUnknown
LIAO SHYHYUAN, CATANI STEVEN J, MERKEL CAROLYN M
CONVERSION OF SUCRALOSE-6-ESTER TO SUCRALOSEDesign not determinedUnknownUnknown
FRY JOHN CHARLES
AN IMPROVED PROCESS FOR THE PREPARATION OF SUCRALOSE OF HIGHPURITYDesign not determinedUnknownUnknown
DESHPANDE PANDURANG BALWANT, LUTHRA PARVEN KUMAR, WADEKAR KASHYAP RAVINDRABHAI, et al.
PROCESS FOR THE PREPARATION OF SUCRALOSE BY THE CHLORINATIONOF SUGAR WITH TRIPHOSGENE (BTC)Design not determinedUnknownUnknown
HO DAVID LOSAN, WAN ZHENGHAO
IMPROVED SUCRALOSE PRODUCTION METHODDesign not determinedUnknownUnknown
KERR JOHN, LEINHOS DUANE, JANSEN BOB, et al.
LE SUCRALOSE SOLUTION STERILE SANS CONSERVATEURSDesign not determinedUnknownUnknown
BOUJBEL LASSARD
Concentrating method and device in acesulfame potassium productionDesign not determinedUnknownUnknown
YINGCHUN YANG
Triethylamine recovery processing method and device for production of acesulfame potassium
Design not determinedUnknownUnknown
YINGCHUN YANG
Conversion of sucralose-6-ester to sucraloseDesign not determinedUnknownUnknown
CHARLES FRY JOHN
Method for separating sucralose-6-esterDesign not determinedUnknownUnknown
JINSHAN WU, ZHENGYOU DING, GUOTING ZHU, et al.
Method for preparing sucraloseDesign not determinedUnknownUnknown
HONG LIN, CHUNLIAN YE, PEILONG LIU
Calorie reduced beverages employing a blend of neotame and acesulfame-kDesign not determinedUnknownUnknown
THOMAS LEE, HYUNG CHANG, MARINELA HONOVICH
Method for separating and washing aspartameDesign not determinedUnknownUnknown
HONGHUI DING, CHUNLONG LI, MINGJIE ZHANG
Sucralose microcapsule and preparation method thereofDesign not determinedUnknownUnknown
XIAN BI, QIAN WEI, MINMIN YE, et al.
Improved sucralose production methodDesign not determinedUnknownUnknown
DUANE LEINHOS, JOHN KERR, BOB JANSEN, et al.
Preparation method of sucraloseDesign not determinedUnknownUnknown
GUANGLI WU, JUNJING WU, QINGHAI CAI, et al.
Chlorination method for industrial production of sucralose-6-acetic esterDesign not determinedUnknownUnknown
JINSHAN WU, GUOTING ZHU, LIJUN AN, et al.
Process for the preparation of sucralose by the chlorination of sugar with triphosgene (BTC)Design not determinedUnknownUnknown
LOSAN HO DAVID, ZHENGHAO WANG
Method for synthesizing sucraloseDesign not determinedUnknownUnknown
XIAN BI, MINMIN YE, DONGLIANG JIANG, et al.
Acidic beverage containing aspartameDesign not determinedUnknownUnknown
YUJI NONAKA, SUSUMU TAKEMOTO
Process for preparing aspartameDesign not determinedUnknownUnknown
WANG FANGDA, CAI YA, WANG LICHENG
Aspartame solutionDesign not determinedUnknownUnknown
HARALD MEYER
Process for biologically synthesizing aspartameDesign not determinedUnknownUnknown
LIANG ZHIQUN WU
Compacted, preferably pressed composition, useful for sweetening food substances, comprises a sweetener including sucralose, and a lubricant e.g. alpha-amino acid, preferably leucineDesign not determinedUnknownUnknown
KRUEGER WILLIBERT
Rapid disintegrating powder, useful to provide additional flavor in e.g. hot drinks, comprises aroma or aroma extract, food fat and/or -oil and/or saturated and/or unsaturated fatty acid, sweeteners such as saccharin and/or aspartameDesign not determinedUnknownUnknown
Acesulfame-containing compositions having improved tasteDesign not determinedUnknownUnknown
RYMON LIPINSKI GERT-WOLFHARD V
Aspartame-sweetened chewing gum and method of producing sameDesign not determinedUnknownUnknown
Glass Michael, Cea Theresa
Process for producing aspartameDesign not determinedUnknownUnknown
Bahl Chander Prakash, Rose Janine Estelle, White Thomas James
Process for the preparation of aspartame.Design not determinedUnknownUnknown
GOURBAULT MAURICE JEAN, CHARDIN ARLETTE, DRESSAIRE GILLES
Stabilized aspartame composition, a process for its production and an aqueous foodDesign not determinedUnknownUnknown
Ojima Takashi, Nagashima Nobuya, Ozawa Toshiyuki
Stabilized aspartame compositionsDesign not determinedUnknownUnknown
Ozawa Toshiyuki, Hattori Hideki
Agglomerating aspartame sweetened products with dextrinsDesign not determinedUnknownUnknown
Ponzoni Ronald William, Kirkpatrick Paul Anthony, Bertalan Charles William
DIETETIC FROZEN DESSERTS CONTAINING ASPARTAMEDesign not determinedUnknownUnknown
WOLKSTEIN Melvin
Aspartame-sweetened gelatin dessert and sweetening composition thereforDesign not determinedUnknownUnknown
Steensen Wayne L., Weaver Ronald C.
A novel tetrachlororaffinose and its use in the preparation of sucraloseDesign not determinedUnknownUnknown
Rathbone Elner Brean, Mufti Khizar Sultan, Khan Riaz Ahmed, et al.
INCORPORATION OF ASPARTAME IN SUGAR-CONTAINING FOODDesign not determinedUnknownUnknown
LERAILLER Eric, THIRIET Bernard, WACQUEZ Jean
Agglomerated bits containing aspartameDesign not determinedUnknownUnknown
Karwowski Jan, Magliacano Anna Maria
A method and product for increased aspartame stability in chewing gumDesign not determinedUnknownUnknown
Glass Michael, Hoholick Joseph, Malinowski Eva (Kielczewski), et al.
Sucralose compositionsDesign not determinedUnknownUnknown
Beyts Pamela Kay
Stabilized sucralose complexDesign not determinedUnknownUnknown
Cherukuri Subraman Rao, Wong Lucy Lee
Sweetening compostions comprising sucralose and isomaltuloseDesign not determinedUnknownUnknown
Beyts Pamela Kay
Process for the preparation of a sweetener based on aspartame, which is in a dry form similar to that of a lump of sugarDesign not determinedUnknownUnknown
Cailler Christiane La Fontaine aux Merles - A1, Luong Albert, Maroteaux Isabelle
Sucralose sweetened chewing gumDesign not determinedUnknownUnknown
Cherukuri Subraman Rao, Wong Lucy Lee, Faust Steven Michael
METHOD OF MAKING A FAST RELEASE STABILIZED ASPARTAME INGREDIENT FOR CHEWING GUMDesign not determinedUnknownUnknown
ZIBELL Steven E., PATEL Mansukh M., DAVE Jayant C., et al.
Enhanced sweetness of acesulfame-K in edible compositionsDesign not determinedUnknownUnknown
Wong Lucy Lee, Faust Steven Michael, Cherukuri Subraman Rao
POLYVINYL ACETATE ENCAPSULATION OF SUCRALOSE FROM SOLUTIONS FOR USE IN CHEWING GUMDesign not determinedUnknownUnknown
YATKA Robert J., BRODERICK Kevin B., SONG Joo H., et al.
POLYVINYL ACETATE ENCAPSULATION OF CODRIED SUCRALOSE FOR USE IN CHEWING GUMDesign not determinedUnknownUnknown
YATKA Robert J., BRODERICK Kevin B., SONG Joo H., et al.
POLYVINYL ACETATE ENCAPSULATION OF CRYSTALLINE SUCRALOSE FOR USE IN CHEWING GUMDesign not determinedUnknownUnknown
YATKA Robert J., BRODERICK Kevin B., SONG Joo H., et al.
Method and device for enzymatic determination of aspartame and cell extract useful thereforDesign not determinedUnknownUnknown
Hummel Werner Dr.
Method of crystallizing aspartameDesign not determinedUnknownUnknown
Ebisawa Kazuyoshi c/o Central Research Lab., Kawaoka Rie c/o Central Research Lab., Nagashima Nobuya c/o Central Research Lab., et al.
Process for the drying and granulation of aspartameDesign not determinedUnknownUnknown
Slangen Hubertus Jozef Maria, Mertens Mathieu Hubertus Marie
Process for the treatment of aspartameDesign not determinedUnknownUnknown
Slangen Hubertus Jozef Maria
Process for the crystallisation of aspartameDesign not determinedUnknownUnknown
Vrinzen Alexander Peter Marie, Rijkers Marinus Petrus Wilhelmus Maria
Method and means for the enzymatic determination of aspartameDesign not determinedUnknownUnknown
Gromes Reiner Dr.
Process and apparatus for recovery of raw materials in the aspartame preparation processDesign not determinedUnknownUnknown
Meindersma Geert Wytze, Vergossen Franciscus Hendrik Paul
Aspartame-containing composition for directly tablettingDesign not determinedUnknownUnknown
Vetsch Werner, Friedl Thomas Dr., Ettmüller Johann
Production of sucralose without intermediate isolation of crystalline sucralose-6-esterDesign not determinedUnknownUnknown
Navia Juan L., Walkup Robert E., Neiditch David S., et al.
CONTROLLING RELEASE OF SUCRALOSE IN CHEWING GUM USING CELLULOSE DERIVATIVES AND GUMDesign not determinedUnknownUnknown
SONG Joo H., RECORD David W., BRODERICK Kevin B., et al.
MEDICINAL ACTIVITY OF ASPARTAMEDesign not determinedUnknownUnknown
GHARBI Abderrahmane
IMPROVED METHOD FOR THE PREPARATION OF AN ASPARTAME-DERIVED COMPOUND USEFUL AS A SWEETENERDesign not determinedUnknownUnknown
NOFRE Claude
CHEWING GUM PRODUCTS CONTAINING A LIQUID ASPARTAME DISPERSIONDesign not determinedUnknownUnknown
TYRPIN Henry T., BRODERICK Kevin B.
Aspartame on a supportDesign not determinedUnknownUnknown
Vleugels Leopold Franciscus Wijnandus
SOLID SUCRALOSEDesign not determinedUnknownUnknown
SANKEY George Henry
ASPARTAME POWDERS FOR POWDER MIXTURESDesign not determinedUnknownUnknown
KEMPER Astrid Elisabeth, SLANGEN Hubertus Jozef Maria
THE USE OF OLIGOSACCHARIDES TO INCREASE THE SWEETNESS AND IMPROVE THE TASTE OF AN ACESULFAME-K/ASPARTAME MIXTUREDesign not determinedUnknownUnknown
DÖRR Margit, JAGER Martin
METHOD FOR PREPARING AND PURIFYING AN N-ALKYLATED ASPARTAME DERIVATIVEDesign not determinedUnknownUnknown
PRAKASH Indra
Synthesis and recovery of aspartame involving enzymatic deformylation stepDesign not determinedUnknownUnknown
Quaedflieg Peter Jan Leonard Mario, Sonke Theodorus, Wagner Adolf Fritz Volker
SWEETENING COMPOSITION COMPRISING ASPARTAME AND 2,4-DIHYDROXYBENZOIC ACIDDesign not determinedUnknownUnknown
BRITTON Sarah Jane, FRY John Charles, LINDLEY Michael George, et al.
NOVEL ASPARTAME CRYSTALS AND PROCESS FOR THE PREPARATION THEREOFDesign not determinedUnknownUnknown
GARTI Nissim, KAMISHNY Alexey, MILHOFER Helga F.
IMPROVED CHEWING GUM FORMULATIONS INCLUDING ASPARTAME AND SODIUM BICARBONATEDesign not determinedUnknownUnknown
YATKA Robert, ZYCK Daniel J.
SWEETENER COMPOSITIONS CONTAINING ASPARTAME AND ASPARTAME DERIVATIVEDesign not determinedUnknownUnknown
KISHISHITA Akihiro, NAGASHIMA Kazutaka
METHOD FOR SEPARATING AND PURIFYING ASPARTAME AND ASPARTAME DERIVATIVEDesign not determinedUnknownUnknown
Nagashima Kazutaka, Kishishita Akihiro
MIXED CRYSTALS COMPRISING ASPARTAME AND ASPARTAME DERIVATIVE AND PROCESS FOR PRODUCING THE SAMEDesign not determinedUnknownUnknown
KISHISHITA Akihirai Ajinomoto Co. Inc., NAGASHIMA Kazutaka Ajinomoto Co. Inc.
PROCESS FOR THE PURIFICATION OF ASPARTAME DERIVATIVEDesign not determinedUnknownUnknown
Amino Yusuke, Takemoto Tadashi
METHOD OF CONTROLLING RELEASE OF N-SUBSTITUTED DERIVATIVES OF ASPARTAME IN CHEWING GUM AND GUM PRODUCED THEREBYDesign not determinedUnknownUnknown
GREENBERG Michael J., JOHNSON Sonya S., SITLER Daniel J., et al.
PREPARATION OF AN ORGANIC SALT OF ASPARTAME WITH ACESULFAM HDesign not determinedUnknownUnknown
GROENEVELD Christiaan
PREPARATION AND PURIFICATION OF A SALT OF ASPARTAME WITH ACESULFAM KDesign not determinedUnknownUnknown
GROENEVELD Christiaan, SNIJDER Carina Sascha, WAGEMANS Gerardus Mathias Cornelus
METHOD OF IMPROVING SWEETNESS DELIVERY OF SUCRALOSEDesign not determinedUnknownUnknown
LINDLEY Michael G., MERKEL Carolyn M.
SYNTHESIS AND RECOVERY OF ASPARTAME INVOLVING ENZYMATIC DEFORMYLATION STEPDesign not determinedUnknownUnknown
QUAEDFLIEG Peter Jan Leonard Mario, SONKE Theodorus, WAGNER Adolf Fritz Volker
SUCRALOSE-CONTAINING COMPOSITION AND EATABLE PRODUCT COMPRISING THE SAMEDesign not determinedUnknownUnknown
OJIMA Naoto San-ei Gen F.F.I. Inc., MADONO Masami San-ei Gen F.F.I. Inc., HIRAO Kazutaka San-ei Gen F.F.I. Inc., et al.
COMPOSITIONS CONTAINING SUCRALOSE AND APPLICATION THEREOFDesign not determinedUnknownUnknown
INOUE Maki, IWAI Kazumi, OJIMA Naoto, et al.
PROCESS FOR PRODUCING ASPARTAME DERIVATIVE, CRYSTALS THEREOF, NOVEL PRODUCTION INTERMEDIATES THEREFOR AND PROCESS FOR PRODUCING THE INTERMEDIATEDesign not determinedUnknownUnknown
KAWAHARAShigeru Amino Scien.Lab.Ajinomoto Co.Inc, NAGASHIMAKazutaka Amino Scie.Lab.Ajinomoto Co.Inc, MORIKenichi Amino Sci.Lab.Ajinomoto Co.Inc., et al.
PROCESSES FOR PRODUCING AND PURIFYING ASPARTAME DERIVATIVES AND PROCESS FOR PRODUCING PRODUCTION INTERMEDIATESDesign not determinedUnknownUnknown
NAGASHIMA KAZUTAKA, FUJITA SHINJI, AOKI YUUICHI, et al.
Non-caking aspartame fine gradeDesign not determinedUnknownUnknown
Kuehn Frank Thomas, Damen Vera Henrica Johanna Thomas
Antimicrobial acesulfame complexes, their preparation and their useDesign not determinedUnknownUnknown
Burgard Andreas Dr.
Film forming composition comprising sucralose and carrageenanDesign not determinedUnknownUnknown
Szymczak Christopher E
Use of acesulfame as a fragranceDesign not determinedUnknownUnknown
Boden Richard M., Beck Charles E.J.
Process for producing a stable aspartame slurry and testing method for determining its stabilityDesign not determinedUnknownUnknown
Tomiyama Yasuyuki c/o Ajinomoto Co. Inc., Kawauchi Masato c/o Ajinomoto Co. Inc.
CHEWING GUM FORMULATIONS INCLUDING ENCAPSULATED ASPARTAME AND SODIUM PYROPHOSPHATEDesign not determinedUnknownUnknown
AUMANN Rebecca A., ROBERT J. Yatka, SAVAGE William D., et al.
IMPROVED SUCRALOSE COMPOSITION AND PROCESS FOR THE CRYSTALLIZATION THEREOFDesign not determinedUnknownUnknown
BROHMI Amal, CATANI Steven J., EL KABBANI Fiesal, et al.
MELTABLE FORM OF SUCRALOSEDesign not determinedUnknownUnknown
LEE Jean, MERKEL Caroloyn M., WANG Ning
NOVEL ASPARTAME POWDERSDesign not determinedUnknownUnknown
SEIGLER Rickey E., KENNY Kerry R., BRYANT Barbara, et al.
SUCRALOSE FORMULATIONS TO MASK UNPLEASANT TASTESDesign not determinedUnknownUnknown
JAEGER David, DICKERSON Jay, MOGAVERO Annabelle
Compositions containing sucraloseDesign not determinedUnknownUnknown
Szymczak Christopher E
EXTRACTIVE METHODS FOR PURIFYING SUCRALOSEDesign not determinedUnknownUnknown
CATANI Steven J., VERNON Nicholas M., NEIDITCH David Saul, et al.
PROCESS FOR IMPROVING SUCRALOSE PURITY AND YIELDDesign not determinedUnknownUnknown
CATANI Steven J., WILEY James Edwin, VERNON Nicholas M., et al.
CARTILAGE ENHANCING FOOD SUPPLEMENTS WITH SUCRALOSE AND METHODS OF PREPARING THE SAMEDesign not determinedUnknownUnknown
STONE Kevin R.
IMPROVED CRYSTALLINE FORM OF SUCRALOSE, AND METHOD FOR PRODUCING ITDesign not determinedUnknownUnknown
CATANI Steven J., MERKEL Carolyn M., VERNON Nicholas M.
Method of producing edible films including aspartameDesign not determinedUnknownUnknown
BARABOLAK ROMAN M, CHAPDELAINE ALBERT H, HOOK JEFFREY S, et al.
GRANULATED SUCRALOSE PRODUCTDesign not determinedUnknownUnknown
LIAO Shyhyuan, MERKEL Carolyn M., CATANI Steven J.
METHOD FOR THE PRODUCTION OF A SWEETENER SALT BASED ON ASPARTAME AND ACESULFAMEDesign not determinedUnknownUnknown
GROER Peter, MERKT Gerhard
MIXTURES WITH A SWEETNESS AND TASTE PROFILE OF HIGH FRUCTOSE CORN SYRUP HFCS 55 COMPRISING HFCS 42 AND ACESULFAME KDesign not determinedUnknownUnknown
RIHA William E., MOLINA-CORTINA Eduardo-Ignacio
Process for improving sucralose purity and yieldDesign not determinedUnknownUnknown
Catani Steven J., Vernon Nicholas M., Merkel Carolyn M., et al.
ASPARTAME SOLUTIONDesign not determinedUnknownUnknown
MEYER Harald
Film forming composition comprising sucralose and carrageenanDesign not determinedUnknownUnknown
SZYMCZAK CHRISTOPHER E
Improving aspartame stability in edible compositionsDesign not determinedUnknownUnknown
Rathjen Susanne Dr., Sälzer Katrin, Schwarz Susanne
Extractive methods for purifying sucraloseDesign not determinedUnknownUnknown
CATANI STEVEN J, VERNON NICHOLAS M, NEIDITCH DAVID SAUL, et al.
Pharmaceutical formulations containing ferrous bisglycinate chelate in combination with sweeteners (acesulfam K, sucralose, sorbitol) for improved palatabilityDesign not determinedUnknownUnknown
BALDACCI MASSIMO
ACIDIC BEVERAGE CONTAINING ASPARTAMEDesign not determinedUnknownUnknown
NONAKA YUJI, TAKEMOTO SUSUMU
PROCESS FOR SYNTHESIZING AND PURIFYING SUCRALOSEDesign not determinedUnknownUnknown
CHEN XINMIN, BAI YANBING, PENG JIANXIN
Sucralose-containing compositionDesign not determinedUnknownUnknown
OJIMA NAOTO, MADONO MASAMI, HIRAO KAZUTAKA, et al.
Calorie reduced beverages employing a blend of neotame and acesulfame-KDesign not determinedUnknownUnknown
LEE THOMAS, CHANG HYUNG, HONOVICH MARINELA
LOW-CALORIE BEVERAGE COMPOSITION CONTAINING LUO HAN GUO EXTRACT AND SUCRALOSEDesign not determinedUnknownUnknown
TAKAICHI AKIHISA
Use of acesulfame K as a flavour modulatorDesign not determinedUnknownUnknown
RATHJEN SUSANNE
Granular sucralose, and method of making itDesign not determinedUnknownUnknown
NEHMER WARREN L, SKELDING WILLIAM R, BAILEY ALEXANDRIA L, et al.
Drink based on natural mineral water - has added ginseng extract together with citric and ascorbic acids, with saccharose or aspartame added for sweetness if desiredDesign not determinedUnknownUnknown
LEOPOLD PR COMOE, REGIS MACIA DR
Sweetening compositions containing a mixture of erythritol and sucraloseDesign not determinedUnknownUnknown
DOULLE BERNARD
Aspartame concentrates for carbonated beveragesDesign not determinedUnknownUnknown
SHARMA SHRI C
Aspartame concentrates stabilised by caramelDesign not determinedUnknownUnknown
SHARMA SHRI C
Chewing gum with sucralose rolling compoundDesign not determinedUnknownUnknown
MCGREW GORDON N, SCHNELL PHILIP G, RECORD DAVID W, et al.
Process for the removal of dimethylamine in the manufacture of sucraloseDesign not determinedUnknownUnknown
KERR JOHN, JANSEN ROBERT, BAIADA ANTHONY, et al.
COOLANT COATING COMPOSITION FOR SUBSTRATES CONTAINING COATING AGENT, HEAT-STABLE HIGH-INTENSITY SWEETENER SUCH AS SUCRALOSE AND NON-VOLATILE COOLING AGENT HAVING EFFECTS OF PROVIDING COOLING SENSATION WITHOUT SUBSTANTIALLY ANY OLFACTORY STIMULATION AND DOSAGE FORMULATION IN EASY-TO-SWALLOW FORMDesign not determinedUnknownUnknown
SZYMCZAK CHRISTOPHER E
PRODUCTION OF CHOCOLATE-COATED SEASONED CUTTLEFISH BY SPRAYING CHOCOLATE LIQUID CONTAINING CORN OIL, STEVIA OR ASPARTAME ON DRESSED CUTTLEFISHDesign not determinedUnknownUnknown
LEE HYU JAE
IMPROVED CRYSTALLINE FORM OF SUCRALOSE, AND METHOD FOR PRODUCING ITDesign not determinedUnknownUnknown
CATANI STEVEN J, MERKEL CAROLYN M, VERNON NICHOLAS M
GRANULATED SUCRALOSE PRODUCTDesign not determinedUnknownUnknown
LIAO SHYHYUAN, MERKEL CAROLYN M, CATANI STEVEN J
GRANULAR SUCRALOSE, AND METHOD OF MAKING ITDesign not determinedUnknownUnknown
NEHMER WARREN L, ELMORE ROY O, SKELDING WILLIAM R, et al.
CONVERSION OF SUCRALOSE-6-ESTER TO SUCRALOSEDesign not determinedUnknownUnknown
FRY JOHN CHARLES
PREPARATION METHOD OF SUCRALOSEDesign not determinedUnknownUnknown
SUNG NAM KYOUNG, YANG KI CHUL, CHOI YEA HOON, et al.
PROCESS FOR THE PREPARATION OF SUCRALOSE BY THE CHLORINATION OF SUGAR WITH TRIPHOSGENE (BTC)Design not determinedUnknownUnknown
HO DAVID LOSAN, WAN ZHENGHAO
GRANULAR SUCRALOSE, AND METHOD OF MAKING IT.Design not determinedUnknownUnknown
BAILEY ALEXANDRIA L, NEHMER WARREN L, ELMORE ROY O, et al.
GRANULATED SWEETENER OR POWDER OF REFINED SUGAR, STANDARD SUGAR AND/OR SUGAR BEET OR SUGARCANE MUSCOVADO, ISOMALTOSE AND FREE-CALORIE SWEETENERS SUCH AS ACESULFAME K, SUCRALOSE, THAUMATIN, VITAMINS, MINERALS, PROTEIN, INSULIN AND COLOUR CHIPS AND THEDesign not determinedUnknownUnknown
SILLAS HECTOR ALEJANDRO ALVAREZ DE LA CADENA, ROJAS OCTAVIO RAMIREZ
CALORIE REDUCED BEVERAGES EMPLOYING A BLEND OF NEOTAME AND ACESULFAME-K.Design not determinedUnknownUnknown
LEE THOMAS, CHANG HYUNG, HONOVICH MARINELA
PROCESS FOR THE PREPARATION OF SUCRALOSE BY THE CHLORINATION OF SUGAR WITH TRIPHOSGENE (BTC).Design not determinedUnknownUnknown
HO DAVID LOSAN, WAN ZHENGHAO
IMPROVED SUCRALOSE PRODUCTION METHOD.Design not determinedUnknownUnknown
BAIADA ANTHONY, LEINHOS DUANE, KERR JOHN, et al.
FILM FORMING COMPOSITIONS CONTAINING SUCRALOSE.Design not determinedUnknownUnknown
SZYMCZAK CHRISTOPHER E
MELTABLE FORM OF SUCRALOSE.Design not determinedUnknownUnknown
WANG NING
SUCRALOSE FORMULATIONS TO MASK UNPLEASANT TASTES.Design not determinedUnknownUnknown
ANNABELLE MOGAVERO
COMPOSITIONS CONTAINING SUCRALOSE.Design not determinedUnknownUnknown
CHRISTOPHER E SZYMCZAK
EDIBLE FILMS INCLUDING ASPARTAME AND METHODS OF MAKING SAME.Design not determinedUnknownUnknown
LEVAKOV VUKASIN
EXTRACTIVE METHODS FOR PURIFYING SUCRALOSE.Design not determinedUnknownUnknown
DAVID SAUL NEIDITCH
PROCESS FOR IMPROVING SUCRALOSE PURITY AND YIELD.Design not determinedUnknownUnknown
EDWARD MICINSKI
IMPROVED CRYSTALLINE FORM OF SUCRALOSE, AND METHOD FOR PRODUCING IT.Design not determinedUnknownUnknown
VERNON NICHOLAS M
GRANULATED SUCRALOSE PRODUCT.Design not determinedUnknownUnknown
LIAO SHYHYUAN
MIXTURES WITH A SWEETNESS AND TASTE PROFILE OF HIGH FRUCTOSE CORN SYRUP HFCS 55 COMPRISING HFCS 42 AND ACESULFAME K.Design not determinedUnknownUnknown
RIHA WILLIAM E
Film forming compositions containing carrageenan and sucraloseDesign not determinedUnknownUnknown
SZYMCZAK CHRISTOPHER E
Use of sucralose as a sweetening agent combined with pH modulation of chemical formulations generates enhanced taste-masking effectsDesign not determinedUnknownUnknown
JAEGER DAVID, DICKERSON JAY, MOGAVERO ANNABELLE
An improved process for producing chlorinated sucrose (sucralose)Design not determinedUnknownUnknown
RATNAM RAKESH, KULKARNI SHRIKANT, AURORA SUNEET
Improved sucralose production methodDesign not determinedUnknownUnknown
LEINHOS DUANE, KERR JOHN, JANSEN BOB, et al.
METHOD FOR PRODUCING OF CHEWING GUM COMPRISING N-SUBSTITUTED ASPARTAME DERIVATIVE (VERSIONS) AND CHEWING GUM PRODUCED BY METHOD (VERSIONS)Design not determinedUnknownUnknown
JATKA ROBERT DZH, TAUNSEND DONAL D DZH, DZHONSON SONJA S, et al.
MELTING SUCRALOSE-CONTAINING SWEETENERDesign not determinedUnknownUnknown
MERKEL KAROLIN M, VANG NING, LI ZHAN
IMPROVED SUCRALOSE-CONTAINING COMPOSITION AND METHOD FOR ITS PREPARINGDesign not determinedUnknownUnknown
EHL KABBANI FISAL, KATANI STIVEN DZH, KHAJSS KRISTIAN, et al.
METHOD OF IMPROVING SWEETNESS DELIVERY OF SUCRALOSEDesign not determinedUnknownUnknown
MERKEL CAROLYN M, LINDLEY MICHAEL G
Method of improving sweetness delivery of sucraloseDesign not determinedUnknownUnknown
MERKEL CAROLYN M, LINDLEY MICHAEL G
Chewable tablets containing mannitol and AspartameDesign not determinedUnknownUnknown
VALENTINE WILLIAM, VALENTINE WILLIAM K
Acesulfame-metal complexes, process for their preparation and their useDesign not determinedUnknownUnknown
BURGARD ANDREAS
Synthesis and recovery of aspartame involving enzymatic deformylation stepDesign not determinedUnknownUnknown
QUAEDFLIEG PETER J L M, SONKE THEODORUS, WAGNER ADOLF F V
Method of controlling release of N-substituted derivatives of aspartame in chewing gum and gum produced therebyDesign not determinedUnknownUnknown
YATKA ROBERT J, TOWNSEND DONALD J, JOHNSON SONYA S, et al.
Sucralose composition and process for its preparationDesign not determinedUnknownUnknown
EL KABBANI FIESAL, BROHMI AMAL, HEISS CHRISTIAN, et al.
Process for producing aspartame derivatives, process for purifying aspartame derivatives, production intermediates, and process for producing production intermediatesDesign not determinedUnknownUnknown
NAGASHIMA KAZUTAKA, FUJITA SHINJI, AOKI YUUICHI, et al.
Chewing gum formulations including encapsulated aspartame and sodium pyrophosphateDesign not determinedUnknownUnknown
SAVAGE WILLIAM D, SCHNELL PHILIP G, AUMANN REBECCA A, et al.
Method for producing aspartame derivative, method for purifying the same, crystals thereof and uses of the sameDesign not determinedUnknownUnknown
AMINO YUSUKE, YUZAWA KAZUKO, TAKEMOTO TADASHI
Acesulfame salt, process for its preparation and its useDesign not determinedUnknownUnknown
BURGARD ANDREAS
Xanthine-and phenazone-acesulfame-H complexes having improved taste, process for their preparation and their useDesign not determinedUnknownUnknown
BURGARD ANDREAS
Novel aspartame powdersDesign not determinedUnknownUnknown
SEIGLER RICKEY E, KENNY KERRY R, BRYANT BARBARA, et al.
Antimicrobially active acesulfame complexes, process for their preparation and their useDesign not determinedUnknownUnknown
BURGARD ANDREAS
USE OF METAL SALTS TO IMPROVE THE TASTE OF LOW-CALORIE BEVERAGES SWEETENED WITH SUCRALOSEDesign not determinedUnknownUnknown
MUTILANGI WILLIAM, AMENEDO PATRICIA, CURTISS HELEN GRAHAM
Method of improving sweetness delivery of sucraloseDesign not determinedUnknownUnknown
MERKEL CAROLYN M, LINDLEY MICHAEL G
Meltable form of sucraloseDesign not determinedUnknownUnknown
MERKEL CAROLYN M, WANG NING, LEE JEAN
Processes for preparing an aspartame slurryDesign not determinedUnknownUnknown
TOMIYAMA YASUYUKI, KAWAUCHI MASATO
Cartilage enhancing food supplements with sucralose and methods of preparing the sameDesign not determinedUnknownUnknown
STONE KEVIN R
Extractive methods for purifying sucraloseDesign not determinedUnknownUnknown
CATANI STEVEN J, VERNON NICHOLAS M, NEIDITCH DAVID SAUL, et al.
Process for improving sucralose purity and yieldDesign not determinedUnknownUnknown
CATANI STEVEN J, WILEY JAMES E, VERNON NICHOLAS M, et al.
Sucralose composition and process for its preparationDesign not determinedUnknownUnknown
EL KABBANI FIESAL, BROHMI AMAL, HEISS CHRISTIAN, et al.
Method for producing Aspartame derivative, method for purifying the same, crystals thereof and uses of the sameDesign not determinedUnknownUnknown
AMINO YUSUKE, YUZAWA KAZUKO, TAKEMOTO TADASHI
Method of controlling release of N-substituted derivatives of aspartame in chewing gum and gum produced therebyDesign not determinedUnknownUnknown
YATKA ROBERT J, TOWNSEND DONALD J, JOHNSON SONYA S, et al.
Crystalline form of sucralose, and method for producing itDesign not determinedUnknownUnknown
CATANI STEVEN J, MERKEL CAROLYN M, VERNON NICHOLAS M
Synthesis and recovery of aspartame involving enzymatic deformylation stepDesign not determinedUnknownUnknown
QUAEDFLIEG PETER J.L.M, SONKE THEODORUS, WAGNER ADOLF F.V
Edible films including aspartame and methods of making sameDesign not determinedUnknownUnknown
BARABOLAK ROMAN M, CHAPDELAINE ALBERT H, HOOK JEFFREY S, et al.
Chilsonated sucralose productDesign not determinedUnknownUnknown
LIAO SHYHYUAN, MERKEL CAROLYN M, CATANI STEVEN J
Mixtures with a sweetness and taste profile of high fructose corn syrup (HFCS) 55 comprising HFCS 42 and acesulfame KDesign not determinedUnknownUnknown
RIHA WILLIAM E, MOLINA-CORTINA EDUARDO-IGNACIO
Sucralose compositionDesign not determinedUnknownUnknown
EL KABBANI FIESAL, BROHMI AMAL, HEISS CHRISTIAN, et al.
Sucralose-containing composition and edible products containing the compositionDesign not determinedUnknownUnknown
OJIMA NAOTO, MADONO MASAMI, HIRAO KAZUTAKA, et al.
Crystalline form of sucralose, and method for producing itDesign not determinedUnknownUnknown
CATANI STEVEN J, MERKEL CAROLYN M, VERNON NICHOLAS M
Aspartame and citrate flavored phosphate salt laxativeDesign not determinedUnknownUnknown
AYALA NELSON, CASWELL MICHAEL L, POST SARAH S, et al.
Aspartame blendDesign not determinedUnknownUnknown
MONFRE JOHN G
Method of improving sweetness delivery of sucraloseDesign not determinedUnknownUnknown
MERKEL CAROLYN M, LINDLEY MICHAEL G
Sucralose formulations to mask unpleasant tastesDesign not determinedUnknownUnknown
JAEGER DAVID, DICKERSON JAY, TRIMMER ANNABELLE
Method for the purification of sucraloseDesign not determinedUnknownUnknown
LIESEN GREG, SRIVASTAVA SUNIL
Granular sucraloseDesign not determinedUnknownUnknown
NEHMER WARREN L, ELMORE ROY O, SKELDING WILLIAM R, et al.
Method of controlling release of N-substituted derivatives of aspartame in chewing gum and gum produced therebyDesign not determinedUnknownUnknown
YATKA ROBERT J, TOWNSEND DONALD J, JOHNSON SONYA S, et al.
Sucralose sweetening compositionDesign not determinedUnknownUnknown
SILVER BARNARD S
Conversion of sucralose-6-ester to sucraloseDesign not determinedUnknownUnknown
FRY JOHN C
Sucralose compositionDesign not determinedUnknownUnknown
KABBANI FIESAL E, BROHMI AMAL, HEISS CHRISTIAN, et al.
Method for the production of a sweetener salt based on aspartame and acesulfameDesign not determinedUnknownUnknown
GROER PETER, MERKT GERHARD
Aspartame stability in edible compositionsDesign not determinedUnknownUnknown
RATHJEN SUSANNE, SAELZER KATRIN, SCHWARZ SUSANNE
Process for purification of sucraloseDesign not determinedUnknownUnknown
DESHPANDE PANDURANG B, LUTHRA PARVEN K, TOMER SANJIV O, et al.
Method of Sucralose Synthesis YieldDesign not determinedUnknownUnknown
WANG FEI, HE HAIBING, YANG XIN, et al.
COMPOSITIONS CONTAINING SUCRALOSE AND APPLICATION THEREOFDesign not determinedUnknownUnknown
INOUE MAKI, IWAI KAZUMI, OJIMA NAOTO, et al.
Process for the preparation of sucraloseDesign not determinedUnknownUnknown
LI SHAOXIONG, CHEN ZIANG, DENG PATRICK
Methods For Determining The Origin Of Sucralose ProductsDesign not determinedUnknownUnknown
FRY JOHN C
Calorie reduced beverages employing a blend of neotame and acesulfame-KDesign not determinedUnknownUnknown
LEE THOMAS, CHANG HYUNG, HONOVICH MARINELA
PROCESS FOR THE PREPARATION OF SUCRALOSE BY THE CHLORINATION OF SUGAR WITH TRIPHOSGENE (BTC)Design not determinedUnknownUnknown
HO DAVID LOSAN, ZHENGHAO WAN
Aspartame and Citrate Flavored Phosphate Salt LaxativeDesign not determinedUnknownUnknown
AYALA NELSON, CASWELL MICHAEL L, POST SARAH S, et al.
METHOD FOR CRYSTALLIZING SUCRALOSEDesign not determinedUnknownUnknown
WANG FEI, HE HAIBING, YU YONGZHU, et al.
METHOD FOR CRYSTALLIZING SUCRALOSEDesign not determinedUnknownUnknown
WANG FEI, HE HAIBING, WU JINSHAN, et al.
PROCESS FOR THE PREPARATION OF SUCRALOSE BY THE DEACYLATION OF TRICHLOROSUCROSE-6-ETHYL ESTERDesign not determinedUnknownUnknown
WANG FEI, HE HAIBING, WU JINSHAN, et al.
Deacylation of sucralose-6-acylatesDesign not determinedUnknownUnknown
LEINHOS DUANE A, DENTEL DAVID A, WILEY JAMES EDWIN
Sucralose production methodDesign not determinedUnknownUnknown
LEINHOS DUANE, KERR JOHN, JANSEN BOB, et al.
Novel chlorination process for preparing sucraloseDesign not determinedUnknownUnknown
XU SHAOJUN
Granular Sucralose, and Method of Making ItDesign not determinedUnknownUnknown
NEHMER WARREN L, ELMORE ROY O, SKELDING WILLIAM R, et al.
Multifunctional and combinational application of aspartame and or futhanDesign not determinedUnknownUnknown
HUGLI TONY E, ADAMS JOHN E
FREEZE DRIED SUCRALOSEDesign not determinedUnknownUnknown
NEHMER WARREN L, KING CHRISTOPHER ROBERT
PARTIAL SUGAR REPLACEMENT WITH SINGLE HIGH INTENSITY SWEETENER ACESULFAME KDesign not determinedUnknownUnknown
SALZER KATRIN
Agglomerates of Sucralose and Polyols, and their Use in Chewing GumsDesign not determinedUnknownUnknown
LOPEZ MICHEL, NEHMER WARREN L
SUCRALOSE PURIFICATION PROCESSDesign not determinedUnknownUnknown
JANSEN ROBERT, WALKER GORDON, KERR JOHN, et al.
PROCESS FOR THE PREPARATION OF SUCRALOSE OF HIGH PURITYDesign not determinedUnknownUnknown
DESHPANDE PANDURANG BALWANT, LUTHRA PARVEN KUMAR, TOMER SANJIV ONKARSINGH, et al.
METHODS AND SYSTEMS FOR PREPARING MATERIALS FOR SUCRALOSE PRODUCTIONDesign not determinedUnknownUnknown
HO DAVID LOSAN, WAN ZHENGHAO
METHODS FOR EXTRACTING AND PURIFYING SUCRALOSE INTERMEDIATEDesign not determinedUnknownUnknown
HO DAVID LOSAN, WAN ZHENGHAO
Use of Sucralose as a Granulating AgentDesign not determinedUnknownUnknown
SZYMCZAK CHRISTOPHER E, SNYDER RYAN, COSTELLO KRISTIN
STERILE SUCRALOSE SOLUTION WITHOUT PRESERVATIVESDesign not determinedUnknownUnknown
BOUJBEL LASSAAD
EFFECT OF CARBOHYDRATE CONCENTRATION ON SUCRALOSE EXTRACTION EFFICIENCYDesign not determinedUnknownUnknown
MICINSKI EDWARD, WILEY JR JAMES EDWIN
Process to Prepare SucraloseDesign not determinedUnknownUnknown
RAJADHYAKSHA MANGESH, SHIRWAIKER AJIT
PROCESS FOR SYNTHESIZING AND PURIFYING SUCRALOSEDesign not determinedUnknownUnknown
CHEN XINMIN, BAI YANBING, PENG JIANXIN
ASPARTAME-CONTAINING ACIDIC BEVERAGESDesign not determinedUnknownUnknown
NONAKA YUJI, TAKEMOTO SUSUMU
Sucralose Formulations To Mask Unpleasant TastesDesign not determinedUnknownUnknown
JAEGER DAVID, DICKERSON JAY, TRIMMER ANNABELLE
METHODS AND SYSTEMS FOR PREPARING MATERIALS FOR SUCRALOSE PRODUCTIONDesign not determinedUnknownUnknown
HO DAVID LOSAN, WAN ZHENGHAO
COMPOSITIONS CONTAINING SUCRALOSE AND APPLICATION THEREOFDesign not determinedUnknownUnknown
INOUE MAKI, IWAI KAZUMI, OJIMA NAOTO, et al.
LOW-CALORIE BEVERAGE COMPOSITION CONTAINING LUO HAN GUO EXTRACT AND SUCRALOSEDesign not determinedUnknownUnknown
TAKAICHI AKIHISA
Preventing tooth demineralization using aspartameDesign not determinedUnknownUnknown
REUSSNER GEORGE H, THIESSEN JR REINHARDT
Aspartame sweetened chewing gum of improved sweetness stabilityDesign not determinedUnknownUnknown
GLASS MICHAEL, CEA THERESA
Cereal presweetened with aspartame and method of preparationDesign not determinedUnknownUnknown
GAJEWSKI ROBERT J
Cereal presweetened with aspartame and cold water soluble gum coating and method of preparationDesign not determinedUnknownUnknown
GAJEWSKI ROBERT J
Cereal presweetened with aspartame and cold water soluble gum coating and method of preparationDesign not determinedUnknownUnknown
GAJEWSKI ROBERT J
Method for agglomerating aspartame and acid-containing mixesDesign not determinedUnknownUnknown
SORGE RICHARD M, PONZONI RONALD W, SHOAF MYRON D
Aspartame-sweetened gelatin dessert and sweetening composition thereforDesign not determinedUnknownUnknown
STEENSEN WAYNE L, WEAVER RONALD C
Dietetic frozen desserts containing aspartameDesign not determinedUnknownUnknown
WOLKSTEIN MELVIN
Process of stabilizing aspartame sweetness in water-containing foodsDesign not determinedUnknownUnknown
OZAWA TOSHIYUKI, HATTORI HIDEKI
Method for making agglomerated bits containing aspartameDesign not determinedUnknownUnknown
KARWOWSKI JAN, MAGLIACANO ANNA M
Aspartame stabilization with cyclodextrinDesign not determinedUnknownUnknown
KARL CURTIS L, SCHYNOLL WOLFRAM G
Sucralose co-crystallized with a nitrogenous baseDesign not determinedUnknownUnknown
JACKSON GRAHAM
Method for solubilization of aspartame in effervescent aqueous systems; and compositionDesign not determinedUnknownUnknown
ALEXANDER THOMAS A, DAHER LAWRENCE J
Method of enhancing the taste perception of sweetness of aspartame and derivatives thereofDesign not determinedUnknownUnknown
SCHIFFMAN SUSAN
Sucralose sweetening compositionDesign not determinedUnknownUnknown
JENNER MICHAEL R, JACKSON GRAHAM
Aseptically-packaged, aspartame-containing puddingsDesign not determinedUnknownUnknown
LESHIK RICHARD R, DEAN JILL P, KRIMM DAGMAR
Deblocking N-formyl aspartame compoundsDesign not determinedUnknownUnknown
QUIRK JENNIFER M
Low moisture sucralose sweetened chewing gumDesign not determinedUnknownUnknown
CHERUKURI SUBRAMAN R
Process for preparing aspartame coated organic acidDesign not determinedUnknownUnknown
TSAU JOSEF H, SEAGLE DENNIS, LAURENZ STEVEN
Polyvinyl acetate encapsulation of codried sucralose for use in chewing gumDesign not determinedUnknownUnknown
YATKA ROBERT J, BRODERICK KEVIN B, SONG JOO H, et al.
Polyvinyl acetate encapsulation of sucralose from solutions for use in chewing gumDesign not determinedUnknownUnknown
YATKA ROBERT J, BRODERICK KEVIN B, SONG JOO H, et al.
Polyvinyl acetate encapsulation of crystalline sucralose for use in chewing gumDesign not determinedUnknownUnknown
YATKA ROBERT J, BRODERICK KEVIN B, SONG JOO H, et al.
Aspartame stability in chewing gum using an acid gelatin systemDesign not determinedUnknownUnknown
BUNCZEK MICHAEL T, URNEZIS PHILIP W
METHOD OF MAKING A FAST RELEASE STABILIZED ASPARTAME INGREDIENT FOR CHEWING GUMDesign not determinedUnknownUnknown
ZIBELL STEVEN F, PATEL MANSUKH M, DAVE JAYANT C, et al.
Method of controlling release of sucralose in chewing gum using cellulose derivatives and gum produced therebyDesign not determinedUnknownUnknown
SONG JOO H, RECORD DAVID W, BRODERICK KEVIN B, et al.
Reduced calorie sucralose sweetened chewing gumDesign not determinedUnknownUnknown
CHERUKURI SUBRAMAN R
Process for the preparation of a sweetener based on aspartame, which is in a dry form similar to that of a lump of sugarDesign not determinedUnknownUnknown
CAILLER CHRISTIANE, LUONG ALBERT T T, MAROTEAUX ISABELLE
Method for the enzymatic determination of aspartameDesign not determinedUnknownUnknown
HUMMEL WERNER
Chewing gum containing aspartame and palatinose oligosaccharideDesign not determinedUnknownUnknown
YATKA ROBERT J
Sucralose compositionsDesign not determinedUnknownUnknown
BEYTS PAMELA K, LILLARD DONALD W, BATTERMAN CYNTHIA K
Chewing gum containing aspartame and maltodextrin or purified maltodextrinDesign not determinedUnknownUnknown
YATKA ROBERT J
Aspartame for its application as a therapeutically active substanceDesign not determinedUnknownUnknown
CREPPY EDMOND
Chewing gum products containing a liquid aspartame dispersionDesign not determinedUnknownUnknown
TYRPIN HENRY T, BRODERICK KEVIN B
Convenient to use aspartame and method of makingDesign not determinedUnknownUnknown
TSAU JOSEF
Process for the treatment of aspartameDesign not determinedUnknownUnknown
SLANGEN HUBERTUS J M
Method and composition for the enzymic determination of aspartameDesign not determinedUnknownUnknown
GROMES REINER
Method and composition for inhibiting decomposition of aspartameDesign not determinedUnknownUnknown
MITCHELL DAVID C
Process for the treatment of aspartameDesign not determinedUnknownUnknown
SLANGEN HUBERTUS J M
Solid sucraloseDesign not determinedUnknownUnknown
SANKEY GEORGE HENRY
Aspartame-sweetened, acidic, powered beverage mixDesign not determinedUnknownUnknown
CHUANG LOCUS Y, BRANDER RITA W, JACKSON RANDALL R
Ready-to-drink, aspartame-sweetened beveragesDesign not determinedUnknownUnknown
LEE THOMAS D, WOOD ROBERT W
Reduction of lingering sweet aftertaste of sucraloseDesign not determinedUnknownUnknown
SHAMIL SYED H
Chewable tablets containing mannitol and aspartameDesign not determinedUnknownUnknown
VALENTINE WILLIAM, VALENTINE WILLIAM K
Dental bleaching compositions containing sucraloseDesign not determinedUnknownUnknown
JENSEN STEVEN D, FISCHER DAN E
Dental bleaching compositions containing sucraloseDesign not determinedUnknownUnknown
JENSEN STEVEN D, FISCHER DAN E
Method of improving sweetness delivery of sucraloseDesign not determinedUnknownUnknown
MERKEL CAROLYN M, LINDLEY MICHAEL G
Acesulfame-metal complexes, process for their preparation and their useDesign not determinedUnknownUnknown
BURGARD ANDREAS
Synthesis and recovery of aspartame involving enzymatic deformylation stepDesign not determinedUnknownUnknown
QUAEDFLIEG PETER J.L.M, SONKE THEODORUS, WAGNER ADOLF F.V, et al.
Hemostatic and acid etch compositions containing sucraloseDesign not determinedUnknownUnknown
ALLRED PETER M, JENSEN STEVEN D
Method of controlling release of N-substituted derivatives of aspartame in chewing gumDesign not determinedUnknownUnknown
YATKA ROBERT J, TOWNSEND DONALD J, JOHNSON SONYA S, et al.
Chewing gum formulations including encapsulated aspartame and sodium pyrophosphateDesign not determinedUnknownUnknown
SAVAGE WILLIAM D, SCHNELL PHILIP G, AUMANN REBECCA A, et al.
Antimicrobially active acesulfame complexes, process for their preparation and their useDesign not determinedUnknownUnknown
BURGARD ANDREAS
USE OF METAL SALTS TO IMPROVE THE TASTE OF LOW-CALORIE BEVERAGES SWEETENED WITH SUCRALOSEDesign not determinedUnknownUnknown
MUTILANGI WILLIAM, AMENEDO PATRICIA, CURTISS HELEN GRAHAM
Sucralose composition and process for its preparationDesign not determinedUnknownUnknown
EL KABBANI FIESAL, BROHMI AMAL, HEISS CHRISTIAN, et al.
Process for producing aspartame derivatives, process for purifying aspartame derivatives, production intermediates, and process for producing production intermediatesDesign not determinedUnknownUnknown
NAGASHIMA KAZUTAKA, FUJITA SHINJI, AOKI YUUICHI, et al.
Xanthine and phenazone-acesulfame-H complexes having improved taste, process for their preparation and their useDesign not determinedUnknownUnknown
BURGARD ANDREAS
Method for producing aspartame derivative, method for purifying the same, crystals thereof and uses of the sameDesign not determinedUnknownUnknown
AMINO YUSUKE, YUZAWA KAZUKO, TAKEMOTO TADASHI
Method for producing Aspartame derivative, method for purifying the same, crystals thereof and uses of the sameDesign not determinedUnknownUnknown
AMINO YUSUKE, YUZAWA KAZUKO, TAKEMOTO TADASHI
Crystalline form of sucralose, and method for producing itDesign not determinedUnknownUnknown
CATANI STEVEN J, MERKEL CAROLYN M, VERNON NICHOLAS M
Method of improving sweetness delivery of sucraloseDesign not determinedUnknownUnknown
MERKEL CAROLYN M, LINDLEY MICHAEL G
Process for improving sucralose purity and yieldDesign not determinedUnknownUnknown
CATANI STEVEN J, WILEY JAMES E, VERNON NICHOLAS M, et al.
Meltable form of sucraloseDesign not determinedUnknownUnknown
MERKEL CAROLYN M, WANG NING, LEE JEAN
Processes for preparing an aspartame slurryDesign not determinedUnknownUnknown
TOMIYAMA YASUYUKI, KAWAUCHI MASATO
Sucralose-containing composition and edible products containing the compositionDesign not determinedUnknownUnknown
OJIMA NAOTO, MADONO MASAMI, HIRAO KAZUTAKA, et al.
Extractive methods for purifying sucraloseDesign not determinedUnknownUnknown
CATANI STEVEN J, VERNON NICHOLAS M, NEIDITCH DAVID SAUL, et al.
Compositions containing sucralose and application thereofDesign not determinedUnknownUnknown
INOUE MAKI, IWAI KAZUMI, OJIMA NAOTO, et al.
Chewing gum product including encapsulated aspartame and sodium bicarbonate and process of preparingDesign not determinedUnknownUnknown
ZYCK DANIEL J, YATKA ROBERT
Method of controlling release of N-substituted derivatives of aspartame in chewing gum and gum produced therebyDesign not determinedUnknownUnknown
YATKA ROBERT J, TOWNSEND DONALD J, JOHNSON SONYA S, et al.
METHOD OF IMPROVING SWEETNESS DELIVERY OF SUCRALOSEDesign not determinedUnknownUnknown
MERKEL Carolyn M., LINDLEY Michael G.
COMPOSITIONS CONTAINING SUCRALOSE AND APPLICATION THEREOFDesign not determinedUnknownUnknown
INOUE Maki, IWAI Kazumi, OJIMA Naoto, et al.
SYNTHESIS AND RECOVERY OF ASPARTAME INVOLVING ENZYMATIC DEFORMYLATION STEPDesign not determinedUnknownUnknown
QUAEDFLIEG PETER JAN LEONARD MARIO, SONKE THEODORUS, WAGNER ADOLF FRITZ VOLKER
SUCRALOSE-CONTAINING COMPOSITION AND EATABLE PRODUCT COMPRISING THE SAMEDesign not determinedUnknownUnknown
OJIMA Naoto, MADONO Masami, HIRAO Kazutaka, et al.
PROCESS FOR PRODUCING ASPARTAME DERIVATIVE, METHOD OF PURIFYING THE SAME, CRYSTALS THEREOF AND USE OF THE SAMEDesign not determinedUnknownUnknown
AMINO Yusuke, YUZAWA Kazuko, TAKEMOTO Tadashi
PROCESSES FOR PRODUCING AND PURIFYING ASPARTAME DERIVATIVES AND PROCESS FOR PRODUCING PRODUCTION INTERMEDIATESDesign not determinedUnknownUnknown
NAGASHIMA KAZUTAKA, FUJITA SHINJI, AOKI YUUICHI, et al.
PROCESS FOR PRODUCING ASPARTAME DERIVATIVE, CRYSTALS THEREOF, NOVEL PRODUCTION INTERMEDIATES THEREFOR AND PROCESS FOR PRODUCING THE INTERMEDIATEDesign not determinedUnknownUnknown
KAWAHARA SHIGERU, NAGASHIMA KAZUTAKA, MORI KENICHI, et al.
NOVEL ASPARTAME POWDERSDesign not determinedUnknownUnknown
SEIGLER Rickey E., KENNY Kerry R., BRYANT Barbara, et al.
NON-CAKING ASPARTAME FINE GRADEDesign not determinedUnknownUnknown
KUEHN Frank Thomas, DAMEN Vera Henrica Johanna Thomas
CHEWING GUM FORMULATIONS INCLUDING ENCAPSULATED ASPARTAME AND SODIUM PYROPHOSPHATEDesign not determinedUnknownUnknown
SAVAGE William D., SCHNELL Phillip G., AUMANN Rebecca A., et al.
IMPROVED SUCRALOSE COMPOSITION AND PROCESS FOR ITS PREPARATIONDesign not determinedUnknownUnknown
EL KABBANI FIESAL, CATANI STEVEN J, HEISS CHRISTIAN, et al.
MELTABLE FORM OF SUCRALOSEDesign not determinedUnknownUnknown
MERKEL Caroloyn M., WANG Ning, LEE Jean
SUCRALOSE FORMULATIONS TO MASK UNPLEASANT TASTESDesign not determinedUnknownUnknown
JAEGER David, DICKERSON Jay, MOGAVERO Annabelle
EXTRACTIVE METHODS FOR PURIFYING SUCRALOSEDesign not determinedUnknownUnknown
CATANI STEVEN J, VERNON NICHOLAS M, NEIDITCH DAVID SAUL, et al.
PROCESS FOR IMPROVING SUCRALOSE PURITY AND YIELDDesign not determinedUnknownUnknown
CATANI Steven J., WILEY James Edwin, VERNON Nicholas M., et al.
CARTILAGE ENHANCING FOOD SUPPLEMENTS WITH SUCRALOSE AND METHODS OF PREPARING THE SAMEDesign not determinedUnknownUnknown
STONE Kevin R.
HEMOSTATIC AND ACID ETCH COMPOSITIONS CONTAINING SUCRALOSEDesign not determinedUnknownUnknown
ALLRED Peter M., JENSEN Steven D.
IMPROVED CRYSTALLINE FORM OF SUCRALOSE, AND METHOD FOR PRODUCING ITDesign not determinedUnknownUnknown
CATANI Steven J., MERKEL Carolyn M., VERNON Nicholas M.
GRANULATED SUCRALOSE PRODUCTDesign not determinedUnknownUnknown
LIAO Shyhyuan, MERKEL Carolyn M., CATANI Steven J.
EDIBLE FILMS INCLUDING ASPARTAME AND METHODS OF MAKING SAMEDesign not determinedUnknownUnknown
BARABOLAK Roman, CHAPDELAINE Albert H., HOOK Jeffrey S., et al.
METHOD FOR THE PRODUCTION OF A SWEETENER SALT BASED ON ASPARTAME AND ACESULFAMEDesign not determinedUnknownUnknown
GROER Peter, MERKT Gerhard
MIXTURES WITH A SWEETNESS AND TASTE PROFILE OF HIGH FRUCTOSE CORN SYRUP HFCS 55 COMPRISING HFCS 42 AND ACESULFAME KDesign not determinedUnknownUnknown
RIHA William E., MOLINA-CORTINA Eduardo-Ignacio
ASPARTAME SOLUTIONDesign not determinedUnknownUnknown
MEYER Harald
METHODS FOR DETERMINING THE ORIGIN OF SUCRALOSE PRODUCTSDesign not determinedUnknownUnknown
FRY John Charles
ASPARTAME AND CITRATE FLAVORED PHOSPHATE SALT LAXATIVEDesign not determinedUnknownUnknown
AYALA Nelson, CASWELL Michael L., POST Sarah S., et al.
GRANULAR SUCRALOSE, AND METHOD OF MAKING ITDesign not determinedUnknownUnknown
NEHMER Warren L., ELMORE Roy O., SKELDING William R., et al.
ACESULFAME-K INULIN SWEETENERDesign not determinedUnknownUnknown
LUDAN Arturo C.
CONVERSION OF SUCRALOSE-6-ESTER TO SUCRALOSEDesign not determinedUnknownUnknown
FRY John Charles
AN IMPROVED PROCESS FOR THE PREPARATION OF SUCRALOSE OF HIGH PURITYDesign not determinedUnknownUnknown
DESHPANDE PANDURANG BALWANT, LUTHRA PARVEN KUMAR, TOMER SANJIV ONKARSINGH, et al.
PREPARATION OF 6-O-BENZOYL SUCRALOSE TETRA-ACETATEDesign not determinedUnknownUnknown
CHEN XIN, CHENG YUE
CALORIE REDUCED BEVERAGES EMPLOYING A BLEND OF NEOTAME AND ACESULFAME-KDesign not determinedUnknownUnknown
LEE THOMAS, CHANG HYUNG, HONOVICH MARINELA
PROCESS FOR THE PREPARATION OF SUCRALOSE BY THE CHLORINATION OF SUGAR WITH TRIPHOSGENE (BTC)Design not determinedUnknownUnknown
HO DAVID LOSAN, WANG ZHENGHAO
IMPROVED SUCRALOSE PRODUCTION METHODDesign not determinedUnknownUnknown
LEINHOS DUANE, KERR JOHN, JANSEN BOB, et al.
DEACYLATION OF SUCRALOSE-6-ACYLATESDesign not determinedUnknownUnknown
LEINHOS DUANE A, DENTEL DAVID A, WILEY JR. JAMES EDWIN
METHOD OF PRODUCING SUCRALOSEDesign not determinedUnknownUnknown
SUNG NAM-KYOUNG, YANG KI-CHUL, CHOI YEA-HOON, et al.
STERILE SUCRALOSE SOLUTION WITHOUT PRESERVATIVESDesign not determinedUnknownUnknown
BOUJBEL LASSAAD
FREEZE DRIED SUCRALOSEDesign not determinedUnknownUnknown
NEHMER WARREN LEE, KING CHRISTOPHER R
NOVEL CHLORINATION PROCESS FOR PREPARING SUCRALOSEDesign not determinedUnknownUnknown
XU SHAOJUN
MULTIFUNCTIONAL AND COMBINATIONAL APPLICATION OF ASPARTAME AND OR FUTHANDesign not determinedUnknownUnknown
HUGLI TONY E, ADAMS JOHN E
ACIDIC BEVERAGE CONTAINING ASPARTAMEDesign not determinedUnknownUnknown
NONAKA YUJI, TAKEMOTO SUSUMU
PROCESS FOR SYNTHESIZING AND PURIFYING SUCRALOSEDesign not determinedUnknownUnknown
CHEN XINMIN, BAI YANBING, PENG JIANXIN
AGGLOMERATES OF SUCRALOSE AND POLYOLS, AND THEIR USE IN CHEWING GUMSDesign not determinedUnknownUnknown
LOPEZ MICHEL, NEHMER WARREN L
METHOD FOR THE PRODUCTION OF SUCRALOSEDesign not determinedUnknownUnknown
KERR JOHN, DENTEL DAVID A, LEINHOS DUANE A, et al.
EXTRACTION OF LESS POLAR IMPURITIES FROM SUCRALOSE CONTAINING AQUEOUS FEED STREAMSDesign not determinedUnknownUnknown
WILEY JAMES EDWIN JR
IMPROVED SUCRALOSE PURIFICATION PROCESSDesign not determinedUnknownUnknown
JANSEN ROBERT, WALKER GORDON, KERR JOHN, et al.
PURIFICATION OF SUCRALOSE CONTAINING FEED STREAMS FOR SUCRALOSE CRYSTALLIZATIONDesign not determinedUnknownUnknown
WILEY JAMES EDWIN JR, KERR JOHN, JANSEN ROBERT, et al.
EFFECT OF CARBOHYDRATE CONCENTRATION ON SUCRALOSE EXTRACTION EFFICIENCYDesign not determinedUnknownUnknown
MICINSKI EDWARD, WILEY JAMES EDWIN
BUFFER RINSED SUCRALOSE CRYSTALSDesign not determinedUnknownUnknown
NEHMER WARREN L, BAILEY ALEXANDRIA L
CRYSTALLIZATION OF SUCRALOSE FROM SUCRALOSE-CONTAINING FEED STREAMSDesign not determinedUnknownUnknown
MICINSKI EDWARD, WILEY JAMES EDWIN, LEINHOS DUANE A, et al.
METHODS FOR EXTRACTING AND PURIFYING SUCRALOSE INTERMEDIATEDesign not determinedUnknownUnknown
HO DAVID LOSAN, WAN ZHENGHAO
USE OF SUCRALOSE AS A GRANULATING AGENTDesign not determinedUnknownUnknown
SZYMCZAK CHRISTOPHER E, SNYDER RYAN, COSTELLO KRISTIN
LOW-CALORIE BEVERAGE COMPOSITION CONTAINING LUO HAN GUO EXTRACT AND SUCRALOSEDesign not determinedUnknownUnknown
TAKAICHI AKIHISA
SUCRALOSE-CONTAINING ARTIFICIAL SWEETENER COMPOSITIONSDesign not determinedUnknownUnknown
KRUEGER WILLIBERT
LIQUID SUCRALOSE SWEETENER COMPOSITIONDesign not determinedUnknownUnknown
SHASTRI PRATIMA N, VASUDEVARAO P
SUCRALOSE SOLUTION AND PREPARATION METHOD THEREOFDesign not determinedUnknownUnknown
BAI YANBING, LIN GUANYU, GUO XINFU, et al.
USE OF ACESULFAME K AS A FLAVOUR MODULATORDesign not determinedUnknownUnknown
RATHJEN SUSANNE
DIETETIC FROZEN DESSERTS CONTAINING ASPARTAMEDesign not determinedUnknownUnknown
WOLKSTEIN Melvin
INCORPORATION OF ASPARTAME IN SUGAR-CONTAINING FOODDesign not determinedUnknownUnknown
LERAILLER Eric, THIRIET Bernard, WACQUEZ Jean
METHOD OF CONTROLLING RELEASE OF ACESULFAME K IN CHEWING GUM AND GUM PRODUCED THEREBYDesign not determinedUnknownUnknown
YATKA ROBERT J
SUCRALOSE COMPOSITIONSDesign not determinedUnknownUnknown
BEYTS Pamela Kay
METHOD OF CONTROLLING RELEASE OF SUCRALOSE IN CHEWING GUM AND GUM PRODUCED THEREBYDesign not determinedUnknownUnknown
YATKA ROBERT J
METHOD OF MAKING A FAST RELEASE STABILIZED ASPARTAME INGREDIENT FOR CHEWING GUMDesign not determinedUnknownUnknown
ZIBELL Steven E., PATEL Mansukh M., DAVE Jayant C., et al.
POLYVINYL ACETATE ENCAPSULATION OF CODRIED SUCRALOSE FOR USE IN CHEWING GUMDesign not determinedUnknownUnknown
YATKA Robert J., BRODERICK Kevin B., SONG Joo H., et al.
POLYVINYL ACETATE ENCAPSULATION OF CRYSTALLINE SUCRALOSE FOR USE IN CHEWING GUMDesign not determinedUnknownUnknown
YATKA Robert J., BRODERICK Kevin B., SONG Joo H., et al.
POLYVINYL ACETATE ENCAPSULATION OF SUCRALOSE FROM SOLUTIONS FOR USE IN CHEWING GUMDesign not determinedUnknownUnknown
YATKA Robert J., BRODERICK Kevin B., SONG Joo H., et al.
LOW MOISTURE SUCRALOSE SWEETENED CHEWING GUMDesign not determinedUnknownUnknown
CHERUKURI Subraman Rao, RAMAN Krishna P., FAUST Steven M.
REDUCED CALORIE SUCRALOSE SWEETENED CHEWING GUMDesign not determinedUnknownUnknown
CHERUKURI Rao Subraman, RAMAN Krishna P., FAUST Steven M.
METHOD OF MAKING CHEWING GUM WITH NATURAL WAX-COATED DELAYED RELEASE SUCRALOSEDesign not determinedUnknownUnknown
RECORD David W., SCHNELL Philip G., ZIBELL Steven E., et al.
CONTROLLING RELEASE OF SUCRALOSE IN CHEWING GUM USING CELLULOSE DERIVATIVES AND GUMDesign not determinedUnknownUnknown
SONG Joo H., RECORD David W., BRODERICK Kevin B., et al.
MEDICINAL ACTIVITY OF ASPARTAMEDesign not determinedUnknownUnknown
GHARBI Abderrahmane
ASPARTAME FOR USE AS A THERAPEUTICALLY ACTIVE SUBSTANCEDesign not determinedUnknownUnknown
CREPPY EDMOND
CHEWING GUM CONTAINING BETA GLUCAN-STABILIZED ASPARTAMEDesign not determinedUnknownUnknown
YATKA Robert J.
A POLYMORPH OF ASPARTAME AND PROCESS FOR THE PREPARATION THEREOFDesign not determinedUnknownUnknown
GARTI NISSIM, MILHOFER HELGA
IMPROVED METHOD FOR THE PREPARATION OF AN ASPARTAME-DERIVED COMPOUND USEFUL AS A SWEETENERDesign not determinedUnknownUnknown
NOFRE CLAUDE, TINTI JEAN-MARIE
CHEWING GUM CONTAINING ASPARTAME AND MALTODEXTRIN OR PURIFIED MALTODEXTRINDesign not determinedUnknownUnknown
YATKA Robert J.
CHEWING GUM CONTAINING ENCAPSULATED COMBINATIONS OF ASPARTAME AND ACESULFAME KDesign not determinedUnknownUnknown
MUHAMMAD Jacara, YATKA Robert J., MCGREW Gordon N., et al.
CHEWING GUM PRODUCTS CONTAINING A LIQUID ASPARTAME DISPERSIONDesign not determinedUnknownUnknown
TYRPIN Henry T., BRODERICK Kevin B.
SOLID SUCRALOSEDesign not determinedUnknownUnknown
SANKEY GEORGE HENRY
CONVENIENT TO USE ASPARTAMEDesign not determinedUnknownUnknown
TSAU Josef
ASPARTAME POWDERS FOR POWDER MIXTURESDesign not determinedUnknownUnknown
SLANGEN Hubertus Jozef Maria, KEMPER Astrid Elisabeth
METHOD AND COMPOSITION FOR INHIBITING DECOMPOSITION OF ASPARTAMEDesign not determinedUnknownUnknown
MITCHELL David C.
REDUCTION OF LINGERING SWEET AFTERTASTE OF SUCRALOSEDesign not determinedUnknownUnknown
SHAMIL Syed H.
THE USE OF OLIGOSACCHARIDES TO INCREASE THE SWEETNESS AND IMPROVE THE TASTE OF AN ACESULFAME-K/ASPARTAME MIXTUREDesign not determinedUnknownUnknown
JAGER Martin, WIEDMANN Margit
METHOD FOR PREPARING AND PURIFYING AN N-ALKYLATED ASPARTAME DERIVATIVEDesign not determinedUnknownUnknown
PRAKASH INDRA
SWEETENING COMPOSITION COMPRISING ASPARTAME AND 2,4-DIHYDROXYBENZOIC ACIDDesign not determinedUnknownUnknown
BRITTON Sarah Jane, FRY John Charles, LINDLEY Michael George, et al.
PROCESS FOR THE PURIFICATION OF ASPARTAME DERIVATIVEDesign not determinedUnknownUnknown
AMINO YUSUKE, TAKEMOTO TADASHI
NOVEL ASPARTAME CRYSTALS AND PROCESS FOR THE PREPARATION THEREOFDesign not determinedUnknownUnknown
MILHOFER Helga F., GARTI Nissim, KAMISHNY Alexey
IMPROVED CHEWING GUM FORMULATIONS INCLUDING ASPARTAME AND SODIUM BICARBONATEDesign not determinedUnknownUnknown
ZYCK Daniel J., YATKA Robert
METHOD FOR SEPARATING AND PURIFYING ASPARTAME AND ASPARTAME DERIVATIVEDesign not determinedUnknownUnknown
NAGASHIMA Kazutaka, KISHISHITA Akihiro
MIXED CRYSTALS COMPRISING ASPARTAME AND ASPARTAME DERIVATIVE AND PROCESS FOR PRODUCING THE SAMEDesign not determinedUnknownUnknown
KISHISHITA AKIHIRO, NAGASHIMA KAZUTAKA
SWEETENER COMPOSITIONS CONTAINING ASPARTAME AND ASPARTAME DERIVATIVEDesign not determinedUnknownUnknown
KISHISHITA AKIHIRO, NAGASHIMA KAZUTAKA
METHOD OF CONTROLLING RELEASE OF N-SUBSTITUTED DERIVATIVES OF ASPARTAME IN CHEWING GUM AND GUM PRODUCED THEREBYDesign not determinedUnknownUnknown
YATKA Robert J., TOWNSEND Donald J., JOHNSON Sonya S., et al.
PREPARATION OF AN ORGANIC SALT OF ASPARTAME WITH ACESULFAM HDesign not determinedUnknownUnknown
GROENEVELD Christiaan
PREPARATION AND PURIFICATION OF A SALT OF ASPARTAME WITH ACESULFAM KDesign not determinedUnknownUnknown
SNIJDER CARINA SASCHA, WAGEMANS GERARDUS MATHIAS CORNELUS, GROENEVELD CHRISTIAAN
AspartameReviewUnknownActive
SucraloseReviewUnknownActive
AcesulfameReviewUnknownActive
Aspartame, Methyleugenol, and IsoeugenolReviewUnknownActive